Aldosterone antagonist moa

    • [DOC File]PRINCIPLES OF CELLULAR FUNCTION - EmergencyPedia

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      Diuretics; which is the correct drug-MOA pairing. thiazides – proximal DCT - true. triamterene – ascending loop of Henle – no, DCT and collecting duct (aldosterone antagonist) spironolactone – loop of Henle – no, DCT and collecting duct. frusemide – collecting duct - no, loop of henle. acetazolamide – DCT - PCT.

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    • [DOC File]Cardiovascular Drugs for Pharmacology Final

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      angiotensin II (AT1) receptor antagonist; inhibits vasoconstriction, aldosterone release and hypertrophic growth. 1st line treatment of . CHF. and . HTN. Fewer side effects than ACE inhibitors. Diuretics not required. Lovastatin HMG-CoA reductase inhibitor See atorvastatin Metoprolol Selective . β. 1 blocker

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    • [DOCX File]Calcium, Phosphate and Vitamin D Disorders

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      Presumed Moa of by-pass Sx, deliver more food to distal intestine to trigger incretin effect ... Tolvaptan: selective V2 antagonist higher receptor affinity compared to ADH, TGA approved for CCF induced hypoNa AND SIADH. ... Renin assay: if suppressed/low renin or high aldosterone-renin ratio then proceed to aldosterone suppression test OR 24hr ...

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    • [DOC File]PHARMACOLOGY BASIC PRINCIPLES

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      Presence of antagonist increases conc of agonist required for given effect ( agonist conc-effect curve will shift to R. Ratio of conc required from certain effect in presence of antagonist v. conc required in absence of antagonist is called dose ratio and is related to Kd (named Kl) of antagonist using Schild equation.

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    • [DOCX File]Academy for FCPS, MD/Ms, PMDC Step | Academy | …

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      MOA of H2 inhibitor/cimetidine ---->Decrease acidity and volume of acid secretion. MOA: Competitive antagonist at the H2 receptor. Blocks H2 receptors in parietal cells which suppresses basal and meal-stimulated acid secretion in a dose-dependent manner.

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    • [DOC File]NAPLEX Review - DrofRx

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      Aldosterone antagonist reduce the risk of death & hospitalization . Diuretics- symptomatic relief . Inotropes: Dobutamine (Dobutrex): MOA: stimulates â-1 receptors causing increased contractility & heart rate, with little effect on â-2 or alpha receptors . â-1 > â-2 > á . Increases CO & vasodilates

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    • [DOC File]Latest Seminar Topics for Engineering CS|IT|ME|EE|EC|AE|CA

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      Anti-hypertensive – Angiotensin II receptor Antagonist. MOA: Inhibits vasoconstrictive and aldosterone – secreting action of angiotensin II receptor on the surface of vascular smooth muscle and other tissue cells. IND: Hypertension. Nephropathy in type 2 DM. Reduce risk of stroke in patients with hypertension and left ventricular hypertrophy

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    • [DOC File]Cholinergic antagonists:

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      MOA: α1 antagonists: Act primarily on the CV system. Vasoconstriction is inhibited, bringing about a net decrease in bp. Decreases smooth muscle contraction and increases ease of urine flow. Overall clinical effect depends on status and specificity of blockage.

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    • [DOC File]PHARMACOLOGY

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      MOA. Increase the excretion of Na+ and water while potassium is retained. It blocks the action of aldosterone on the renal tubules leading to loss of Na+ and water hence retention of K+.Therefore inhibit exchange of Na+ ions for potassium in the distal kidney tubules. Indications. Congestive cardiac failure, nephrotic syndrome and hepatic ...

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