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  • autoimmune disorders definition

    • A concept on the role of Helicobacter pylori infection in ...

      physiology of the above mentioned autoimmune disorders [27-31,33], we propose that this organism might trigger AIP through induction of autoimmu-nity and apoptosis [47]. Definition and terminology of AIP AIP can be defined as an inflammatory process of the pancreas due to an autoimmune mechanism establishing etiology of chronic pancreatitis [48].

    • Genomics and the Multifactorial Nature of Human Autoimmune ...

      have been shown to be associated with one or more autoimmune disorders.2-26 In many cases, the precise causal alleles or genes that drive these associations have not been identified. Nevertheless ...

    • Hashimoto's Disease

      Hashimoto's Disease National Endocrine and Metabolic Diseases Information Service What is Hashimoto's disease? Hashimoto's disease, also called chronic . lymphocytic thyroiditis or autoimmune thyroiditis, is an autoimmune disease. An autoimmune disease is a disorder in which the body's immune system attacks the body's own cells and ...

    • PDF :: Type 1 autoimmune polyendocrinopathy - Orphanet

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      Definition: Type 1 autoimmune polyendocrinopathy is an autosomal recessive genetic autoimmune disease of juvenile onset, combining chronic mucocutaneous candidiasis and various autoimmune endocrinopathies, the most common of which are hypoparathyroidism and adrenal insufficiency. Other autoimmune disorders are


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      The autoimmune diseases can be divided into systemic, localized and haemolytic disorders, depending on tissue/cells affected and the clinico-pathologic features 64.3.1 Systemic autoimmune diseases These diseases are associated with auto antibodies to antigens which are not tissue specific. One example can be polymyositis, here the tissue ...

    • PDF An official European Respiratory Society/American Thoracic ...

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      The CTDs are a spectrum of systemic autoimmune disorders and include rheumatoid arthritis, systemic lupus erythematosus, inflammatory idiopathic myopathies, Sjögren's syndrome, systemic sclerosis and mixed connective tissue disease. Though these diseases have unique and distinguishing features, they share

    • PDF Autoimmune Bullous Dermatoses: A Review

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      A selection of autoimmune blistering diseases, including pemphigus vulgaris, paraneoplastic pemphigus, bullous pemphigoid, cicatricial pemphigoid, der- matitis herpetiformis and linear IgA ...

    • PDF Autoimmune Disease: Mechanisms Article Contents - Roitt

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      example, patients with the autoimmune thyroid diseases, Graves' disease or Hashimoto's thyroiditis, have a family history of developing one or the other of these diseases. Patients with autoimmune thyroid disease are also more likely to develop other autoimmune diseases like systemic lupus erythematosus (lupus), pernicious anaemia, type I

    • PDF Autoimmune Disorder and Autism - InTech

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      autoimmune disorders in some families with autism, suggesting immune dysfunction plays a role in autism pathogenesis [26]. Consistent with this result, Sweeten et al investigated the frequency of autoimmune disorders in families that have probands with pervasive developmental disorders and autism, compared with control groups. Autoimmunity was

    • PDF Autoimmune Disorders: an Overview of Molecular and Cellular ...

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      Although the definition appears relatively simple in concept, the complexity of this spectrum of disorders is enormous, and has greatly ... Autoimmune Disorders: an Overview of Molecular and Cellular Basis in Today's Perspective ...

    • PDF Autoimmune Hepatitis

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      Autoimmune Hepatitis Maricruz Crespo, M.D. ... Definition • Progressive inflammatory disease characterized by increased serum IgG, presence of auto-antibodies and histological liver ... • Genetic disorders -like Progressive Familial Intrahepatic Cholestasis • Metabolic disorders.

    • PDF Autoimmunity

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      Autoimmune diseases Autoimmune disorders are a broad spectrum of disease that can affect any part of the body. More than 80 have been identified, a considerable number with similar symptoms. Inflammation is the classic sign of autoimmunity although how this impacts on

    • PDF Body System Project

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      Body System Project ... A description of at least 2 disorders/diseases that can affect this system. ... At least one immune system disease given should be an autoimmune disorder (include definition of autoimmune disorder).

    • PDF By Lauren Gerstmann, MPH - IG Living

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      By definition, an immune deficiency is a decreased abilityof the immune system to fight infection, whereas autoimmunity is an increased (and abnormal) response of the immune ... autoimmune conditions, including rheumatoid arthritis, systemic lupus erythematosus, pernicious anemia and ITP.

    • PDF Chiropractic and Autoimmune Diseases - Living Well Chiropractic

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      Chiropractic and Autoimmune Diseases Issue 3, November 2010 And the cost to treat autoimmune disorders is almost double the costs associated with cancer. Much more attention should be given to this collection of disorders to find a cure. What Causes Autoimmune Disease? The cause of most autoimmune diseases remains a mystery. However,

    • PDF Epilepsy Associated with Systemic Autoimmune Disorders

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      autoimmune disorders (Table 1), and the first clinical challenge is to determine not only the cause but also the significance of seizures. In some cases, they are clues to metabolic or infectious disorders or medication toxicity; in other cases, seizures herald a life-threatening progression of the underlying illness. Table 1.

    • PDF Hematopoietic Stem-Cell Transplantation for Autoimmune ...

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      Hematopoietic Stem-Cell Transplantation for Autoimmune Diseases 2 The evidence for HSCT in individuals who have systemic sclerosis/scleroderma includes RCTs and observational studies. Relevant outcomes are overall survival, symptoms, health status measures, quality of life, treatment-related mortality, and treatment-related morbidity.

    • PDF Immune diseases and children

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      Hypersensitivity disorders are the most prominent forms of immunotoxicity recognized in humans. Hypersensitivity is an exaggerated response to an antigenic stimulus, commonly distinguished by a reduced threshold to antigen response. Regardless of their type, all

    • PDF Intractable Hypoglycemia in the Setting of Autoimmune Overlap ...

      autoimmune disorders. The presence of multiple autoimmune disorders places her in the category of autoimmune overlap syndrome (Table 1). Autoimmune overlap syndrome is defined as the presence of ≥2 autoimmune diseases in a patient, and this classification helps in defining management and understanding the prognosis of

    • PDF Mechanisms of Autoimmunity

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      in autoimmune testitis. Therefore, autoimmune diseases are distinguished from mere auto-immune response not by the presence /absence of autoimmune response, but by the different quality and quantity of the autoimmune response. Autoimmune diseases are divided into two groups: the organ-specific autoimmune diseases,

    • PDF NIEHS Autoimmune Diseases fact sheet

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      Autoimmune diseases are becoming increasingly prevalent, for reasons unknown. Some autoimmune diseases are life-threatening, and most are . Human Immune System debilitating and require a lifetime of treatment. There are treatments available to reduce the symptoms and effects from many autoimmune diseases, but cures have yet to be discovered.

    • PDF Psychological Profiles in Autoimmune Disease: Relationship to ...

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      psychological profiles in autoimmune disease: relationship to demographic, diagnostic, disease activity and social support measures by rebecca jump a dissertation presented to the graduate school of the university of florida in partial fulfillment of the requirements for the degree of doctor of philosophy university of florida 2005

    • PDF Rituximab: An Autoimmune Disease Therapy - IG Living

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      autoimmune disorders with varying degrees of success. This use of rituximab is considered by the FDA as off-label, but it may be considered when other traditional first - line therapies have failed for autoimmune diseases such as pemphigus, Guilla in-Barré syndrome, polymyositis/ der matomyositis and myasthenia gravis.

    • PDF Shingles and Auto Immune Disorders

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      Non-organ-specific autoimmune disorders. • rheumatoid arthritis, multiple sclerosis, lupus and myasthenia gravis Autoimmune process has varied consequences. •slow destruction of a particular type of cell or tissue •stimulation of an organ into excessive growth or interference in its functions. Organs and tissues frequently

    • PDF Systemic autoimmune disease

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      Sjogrens syndrome (SS) is a relatively common autoimmune disorder characterised by exocrinopathy resulting in the cardinal manifestations of keratoconjunctivitis sicca (90%) and xerostomia (80%). When these manifestations occur in the absence of another clearly defined connective tissue disease, the diagnosis is primary Sjogren's syndrome.

    • PDF Tests for Autoimmune Diseases

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      at greater risk of developing autoimmune disease than men. Autoimmune disease commonly occurs in multiple members of a family, indicating a genetic predisposition. Family members are affected by various autoimmune disorders rather than one specific disorder. 4. Q: What is the first test to be considered for a patient suspected of having an ...

    • PDF Topic Page: Autoimmune diseases

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      Topic Page: Autoimmune diseases Definition: autoimmune diseases from The Penguin Dictionary of Science Disorders of the immune system that result in the inability to differentiate between 'self' and 'non-self' antigens, leading to the production of an auto-antibody (an antibody against oneself). Such diseases

    • PDF Unit 12- Auto Immune Disease

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      4 Definition Autoimmune disorder may result in: Destruction of one or more types of body tissue Abnormal growth of an organ Changes in organ function There are more than 80 different types of autoimmune disorders Who Gets Autoimmune Diseases? Affects 23.5 million Americans Women often start seeing symptoms in their

    • PDF Vaccination and autoimmune disease: what is the evidence?

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      Autoimmune diseases affect about 5% of individuals in developed countries.1 Although the prevalence of most autoimmune diseases is quite low, their individual incidence has greatly increased over the past few years, as documented for type 1 diabetes2,3 and multiple sclerosis.4 Several autoimmune disorders arise in individuals in age-