Calculating statistical significance

    • [PDF File]Statistics: An introduction to sample size calculations

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      Statistics: An introduction to sample size calculations Rosie Cornish. 2006. 1 Introduction One crucial aspect of study design is deciding how big your sample should be. If you increase your sample size you increase the precision of your estimates, which means that, for any given

    • [PDF File]When is statistical significance not significant? - SciELO

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      The statistical difficulties arise more generally with findings that are sug-gestive but not statistically significant. (A. Gelman and D. Weakliem) The research methodology literature in recent years has included a full frontal assault on statistical significance testing. (J. E. McLean and J. M. Ernest)

    • [PDF File]How To Run Statistical Tests in Excel

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      How To Run Statistical Tests in Excel Microsoft Excel is your best tool for storing and manipulating data, calculating basic descriptive statistics such as means and standard deviations, and conducting simple mathematical operations on your numbers. It can also run the five basic Statistical Tests.

    • [PDF File]Is it statistically significant? The chi-square test

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      Steps to follow • State the hypothesis • Calculate the expected values • Use the observed and expected values to calculate the chi-square test statistic • Establish the significance level you need (usually 95% p = 0.05) and the number of degrees of freedom • Compare the chi-square statistic with the critical value from the table • Make a decision about your hypothesis 4 February 2014

    • [PDF File]Calculating Statistical Significance of Trend Slopes

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      Calculating Statistical Significance of Trend Slopes Calculation Method The measure used is the coefficient of the slope of the regression line for the time period. This coefficient is derived using the least squares method from rates for each year and then compared to zero using the student's T test. If the t value is less than a T table value ...

    • [PDF File]P Values, Statistical Significance & Clinical Significance

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      P Values, Statistical Significance & Clinical Significance When looking at the results of a research study, a practitioner has to answer two big questions: 1. Were the results due to chance? 2. Are the results big enough to matter to a patient? P values and Statistical Significance

    • [PDF File]Overlapping Confidence Interval and Statistical Significance

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      Overlapping Confidence Intervals and Statistical Significance . October 2008 . In this issue of StatNews, we address the question: can we judge whether two statistics are significantly different depending on whether or not their confidence intervals overlap? The answer is: not always. If two statistics have

    • Statistical versus Practical Significance - The Atrium

      Calculating power consists of 3 steps: 1) State H0, Ha and the significance level α. 2) Find the mean value (x) that will direct us to reject H0. 3) Calculate the likelihood of observing these values of x when the alternative is true. Calculations of power are beyond the scope of this particular tutorial. It is essential to understand though, that power is an important consideration when planning a study. Power …

    • [PDF File]Effect size, confidence interval and statistical significance: a ...

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      changing statistical practice for the better in the biological sciences. Key words: Bonferroni correction, confidence interval, effect size, effect statistic, meta-analysis, null hypothesis significance testing, p value, power analysis, statistical significance. CONTENTS

    • Calculating the statistical significance of rare variants causal for ...

      Calculating the statistical significance of rare variants causal for Mendelian and complex disorders Aliz R. Rao1* and Stanley F. Nelson1,2,3 Abstract Background: With the expanding use of next-gen sequencing (NGS) to diagnose the thousands of rare Mendelian genetic diseases, it is critical to be able to interpret individual DNA variation. To ...

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