D2 receptor antagonism
[DOC File]Psychotic Disorders - Brown University
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Neuroleptic malignant syndrome comes about, most likely, as a result of dopamine D2 receptor antagonism. Dopamine is a chemical substance (neurotransmitter) found in the brain and elsewhere in the central nervous system that acts to convey messages from one cell to another. In some way, a drug may block the receptor in the brain cell for ...
[DOC File]CHANA K. AKINS - Psychology
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The fact that many drugs used for psychosis are 5-HT 2A [as well as dopamine D2] receptor antagonists, coupled with the fact that agonists at the 5-HT 2A. receptor [e.g. LSD] are psychotomimetic has led many to wonder if antagonism of this receptor could in itself be therapeutic in psychosis. Trials with relatively pure 5-HT 2A. antagonists [e.g.
[DOC File]ECT and NMS - Ce4less
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Dopamine D2/D3 receptor antagonism attenuates copulatory responses in male Japanese quail. Presented at Midwestern Psychological Association meeting in Chicago, IL. Akins, C.K. (1997). The nature of sexually conditioned behavior: CS relevance and CS-US interval determinants. Presented at the Psychonomic Society meeting in Philidelphia, PA.
Mechanism of new antipsychotic medications: occupancy is not jus…
Current pharmacological treatments for schizophrenia all possess dopamine D2 receptor antagonism. Initially, dopamine antagonists increase firing rates of dopamine neurons in the substantia nigra and ventral tegmental area, presumably acting via presynaptic D2 autoreceptors.
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