Epa chronic toxicity testing

    • [DOC File]1 - United States Environmental Protection Agency

      https://info.5y1.org/epa-chronic-toxicity-testing_1_85bba5.html

      Therefore, EPA has suggested that traditional chronic toxicity test endpoints specified in the Guidelines may not be sufficiently comprehensive, and Guidelines requirements for taxonomic coverage in toxicity testing may not be appropriate to derive aquatic life criteria for these chemicals.

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    • [DOCX File]Protecting our way of life | EPA

      https://info.5y1.org/epa-chronic-toxicity-testing_1_f1762d.html

      To address animal welfare concerns, the OECD Guidance Document on Considerations for Waiving or Bridging of Mammalian Acute Toxicity Tests (Series on Testing & Assessment No. 237) should be taken into account when considering testing for acute toxicity, skin …

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    • NPDES Fact Sheet Template, Revision November 2020

      The measured effect may be fertilization, growth, reproduction, or survival. EPA’s methodology includes both an acute test and a chronic test. An acute WET test is considered to show toxicity if adverse affects occur at effluent concentrations less than what is found at …

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    • [DOCX File]1.Introduction - United States Environmental Protection Agency

      https://info.5y1.org/epa-chronic-toxicity-testing_1_d47ca9.html

      LCx toxicity endpoints range from LC 0.1 to LC 90. with values ranging from 570 to 46000 µg/L. Twenty-four other studies report lethal values (coded as NR-leth in ECOTOX) with toxicity values ranging from 26 to 60,000 µg/L.

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    • [DOCX File]EPA Reviewer:

      https://info.5y1.org/epa-chronic-toxicity-testing_1_a33664.html

      toxicity and pathogenicity study for estuarine and marine animal testing (OCSPP 885.4280; PMRA: M9.6 and OECD: IIM 8.2, IIIM 10.2) in the [species] DEFICIENCIES

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    • [DOCX File]Regression Analysis of Exposure Response Data from Chronic ...

      https://info.5y1.org/epa-chronic-toxicity-testing_1_bffb39.html

      The data used in this report were extracted from the AquaChronTox (ACT) database; this database is a compilation of chronic toxicity data for aquatic animals obtained from studies that would meet the definition of an acceptable chronic test under the 1985 Ambient Water Quality Criteria (AWQC) Guidelines (US EPA, 1985) and/or under the effects assessment framework applied for evaluating the ...

      animal toxicity testing


    • [DOC File]OECD.org - OECD

      https://info.5y1.org/epa-chronic-toxicity-testing_1_092df8.html

      - OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)- OECD Guideline 235 (Chironomus sp., Acute Immobilisation Test)- EU Method C.2 (Acute Toxicity for Daphnia)- EPA OPP 72-2 (Aquatic Invertebrate Acute Toxicity Test)- EPA OPP 72-3 (Estuarine/Marine Fish, Mollusk, or Shrimp Acute Toxicity Test)- EPA OPPTS 850.1010 (Aquatic Invertebrate ...

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    • [DOC File]EPA Reviewer:

      https://info.5y1.org/epa-chronic-toxicity-testing_1_2c0c0a.html

      OECD 202 In an acute toxicity study designed for chemical toxicity testing, daphnids are exposed to the test substance for 48 hours. Immobility is the endpoint of interest. OECD 211 In a chronic toxicity study designed for chemical toxicity testing, daphnids are exposed to the test substance for 21 days.

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    • [DOCX File]United States Environmental Protection Agency | US EPA

      https://info.5y1.org/epa-chronic-toxicity-testing_1_4e509e.html

      EPA recommends that the highest test concentration is either the solubility limit of the test compound, 100 mg/L, or demonstrates adequate evidence of toxicity (e.g., 1/3 the 96-hour LC 50

      acute toxicity and chronic toxicity


    • [DOC File]United States

      https://info.5y1.org/epa-chronic-toxicity-testing_1_751401.html

      (7101) EPA 712-C-16-005. October 2016 Ecological Effects. Test Guidelines. OCSPP 850.1300: Daphnid Chronic Toxicity Test NOTICE. This guideline is one of a series of test guidelines established by the United States Environmental Protection Agency’s Office of Chemical Safety and Pollution Prevention (OCSPP) for use in testing pesticides and chemical substances to develop data for submission ...

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