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Appears to increase serotonin turnover, inhibit reuptake of norepinephrine, augment dopaminergic activity, and increase folate5 . Half-life of iv form is 80-100 minutes2 . Not eliminated, but metabolized in many sites. Must use enteric oral form, as stomach digests it2 . Proper use of this medication:
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[DOCX File]Vasopressors and Inotropes in Shock 2019
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First, norepinephrine can be titrated much more easily. Second, vasopressin can have significant effects on cardiac output and splanchnic perfusion. Third, the half-life of norepinephrine is 4-10 times longer than vasopressin which may help avoid rebound hypotension upon drug discontinuation (41,42).
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[DOC File]Nursing CEUs Online - No Test Required | NurseCe4Less.com
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At this time, serial (multiple) blood level determinations should show a decline with time. The amount of time required to eliminate half of the drug from the body is called the half-life. Generally, it takes six half-lives to rid the body of 98% of a drug and 10 half-lives to completely eliminate the drug from the body.
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[DOCX File]medwiki.students.jh.edu
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Depending on the half-life of the drug, it might take a long or short amount of time to reach the desired [drug] If there is exactly one half-life in the dosing interval, then R …
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[DOC File]Routes of Drug Administration
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IV>TD>IM=SC>Rectal>Oral=Inhal Volume of Distribution. Rate of Elimination Vd=Amt of drug in the mody/[drug] ... Increase norepinephrine and serotonin by preventing neuronal reuptake, strong interaction with alcohol. ... extends half-life of dopamine, Indirect dopamine agonists, Treats Parkinsons, also antidepressant ...
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[DOCX File]Noradrenaline (Norepinephrine)
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Half-life: 3 minutes.2. Indications. To increase blood pressure in acute, severe, hypotensive states when low systemic vascular resistance persists despite adequate fluid resuscitation.2 . Noradrenaline is the vasopressor of choice for managing septic shock.3. Precautions
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Half life of norepinephrine iv