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[DOC File]Medical Opinion – Penny D Hardy
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Within one week of switching to atorvastatin 40mg he developed myopathy, rhabdomyolysis and renal failure and later died; an interaction between the two drugs was considered the cause [4]. Administration of fluconazole (400mg on day 1 followed by 200mg for three days) to 12 healthy subjects taking fluvastatin 40mg resulted in an 84% increase in ...
symptoms of rhabdomyolysis from exercise

[DOC File]rosuvastatin - CBG/MEB
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Symptoms arose in every age group, though more often in patients over the age of 50. Examples are: Memory loss. Forgetfulness. Confusion “Fuzzy” or unfocused thinking. Treatment and Complications. Treatment includes rapid rehydration, as most cases of rhabdomyolysis are caused by …
early symptoms of rhabdomyolysis

[DOC File]Shared Care Policy and Prescribing Information for General ...
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Effects on skeletal muscle e.g. myalgia, myopathy and, rarely, rhabdomyolysis have been reported in Crestor-treated patients with all doses and in particular with doses > 20 mg. Very rare cases of rhabdomyolysis have been reported with the use of ezetimibe in combination with …
rhabdomyolysis symptoms statins

[DOCX File]How is acute hypophosphataemia treated in adults?
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The dose of simvastatin should not exceed 20mg daily in patients receiving concomitant medication with amiodarone, due to the increased risk of myopathy and rhabdomyolysis. Amiodarone sensitises the skin to sunlight, patients can burn very easily. Exposure to direct sunlight also produces pigmentation of the skin, which can be permanent.
rhabdomyolysis vs myositis

[DOC File]STATIN-FIBRATE REPORT: Focus on Safety
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However, myopathy and rhabdomyolysis are known adverse reactions to statins and other lipid-lowering drugs. In clinical trials, the incidence of CPK > 10 X ULN was 4 of 1674 (0.2%) patients administered EZETROL alone vs. 1 of 786 (0.1%) patients administered placebo, and for 1 of 917 (0.1%) patients co-administered EZETROL and a statin vs. 4 of ...
early signs of rhabdomyolysis

[DOC File]www.pbm.va.gov
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Clinical features of anti-SRP positive and paraneoplastic associated necrotizing myopathies are similar to statin-induced autoimmune myositis, and include significantly elevated serum CK levels (usually >3000 IU), rapid onset of symptoms with weakness and dysphagia due to a severe myopathy (9-11).
rhabdomyolysis and autoimmune myopathy

[DOCX File]hnfolz.weebly.com
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Confirmed myopathy (defined as creatine kinase >10 x ULN + unexplained muscle sx): 53 (1%) simva 80 mg vs. 2 (0.03%) simva 20 mg. Rhabdomyolysis (defined as CK >40 x ULN with symptoms of end organ damage, doubling of SCr.): 7 (0.1%) simva 80 vs. 0 simva 20 mg. The A to Z Trial: de Lemos JA, Blazing MA, Wiviott SD, et al.
lipitor rhabdomyolysis symptoms

[DOC File]Product Information for Ezetrol (ezetimibe)
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Symptoms may include (1-4): myopathy, rhabdomyolysis, weakness. respiratory failure. arrhythmias, cardiomyopathy. irritability, confusion, hallucinations, somnolence, convulsions, coma. Answer. At LTHT phosphate replacement is prescribed for patients with severe hypophosphataemia (serum phosphate concentration < 0.3mmol/L). For patients with ...
myopathy or rhabdomyolysis

Rhabdomyolysis: Causes, Symptoms, and Diagnosis
Niacin – simvastatin: increase risk of rhabdomyolysis with niacin doses > 1 g/day . What risk factors does he have for developing a myopathy? Multiple drug-drug interactions . Multiple drugs that can cause myopathy. Alcoholic – acute on chronic (Monday after the weekend) Simvastatin 80 mg. Possible hepatic damage from chronic ETOH
symptoms of rhabdomyolysis from exercise

[DOCX File]Title: Statin Induced Autoimmune Myopathy
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Myopathy: General term referring to any disease of the muscle (acquired or inherited). Rhabdomyolysis: Muscle symptoms with significant CK elevation (typically more than 10 times the upper limit of normal). Also with creatinine elevation, brown urine and myoglobin present in the urine. Appendix 2. Cost of Selected Lipid-Lowering Agents
early symptoms of rhabdomyolysis

Myopathy and rhabdomyolysis symptoms