Periventricular white matter disease
Progressive impairment in white matter function with ...
Periventricular rims with high signal on T1-weighted image (A) and low signal on T2-weighted image (B) are shown (white arrows). These findings have been reported in the patients with infantile- and juvenile-onset Alexander disease.2
Ohio University
When white matter disease is encountered on an imaging study, it is useful to first characterize the white matter involvement as multifocal, confluent / diffuse, or selective (geographic). This approach, combined with the clinical information regarding patient demographics, clinical history and physical findings, helps the imager limit the ...
Definition of Periventricular White Matter Disease | Healthfully
Primary hypotheses: patients who have a high burden of periventricular white matter hyperintensities (pvWMH) will have a higher likelihood of positive amyloid scans; the volume of pvWMH will correlate with standardized measures of florbetapir uptake; patients with a high burden of pvWMH volumes will show greater increases in amyloid deposition.
[DOC File]Organism - University of Kentucky
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Average T 2 * values were 3.4 ± 0.2 ms and 23.5 ± 1.8 ms in white matter (WM), for the short and long components respectively, as well as 3.9 ± 0.5 ms and 26.3 ± 2.6 ms for the short and long components respectively in grey matter (GM) using the bi-exponential model. Continuous distribution fits yielded results of 3.1 ± 0.3 ms and 18.8 ± 3.2 ms in WM, for the short and long components ...
[DOCX File]Lippincott Williams & Wilkins
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However, more sensitive imaging is finding that MS at least sometimes includes more than the “hit and skip” areas where plaques are seen; that is, there may be more widespread or diffuse damage to white matter (and gray matter)—that in past imaging—appeared normal or unaffected; this affected but sometimes normal appearing tissue is called “normal-appearing white matter” (NAWM) and ...
[DOCX File]Consensus statement for diagnosis of subcortical small ...
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Generally, including in this review, CSVD is used to describe a series of imaging changes in white matter and subcortical grey matter, including recent small subcortical infarct, lacunes, white matter hyperintensities (WMH), prominent perivascular spaces (PVS), …
[DOCX File]Welcome | NINDS Common Data Elements
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Assessing white matter ischemic damage in dementia patients by measurement of myelin proteins. J Cereb Blood Flow Metab 33:1050–7. Barker R, Ashby EL, Wellington D, Barrow VM, Palmer JC, Kehoe PG, Esiri MM, Love S. 2014. Pathophysiology of white matter perfusion in Alzheimer's disease and vascular dementia. Brain. 137(Pt 5):1524-32.
[DOCX File]Update on small vessel diseases
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Periventricular Germinal Matrix Preterm. Periventricular Germinal Matrix Most common neonatal intracranial hemorrhage. PV Germinal Matrix is fragile, fibrinolytic & persists until 34 weeks. Variable: May be focal & asymptomatic, may spread into ventricles Periventricular Leukomalacia (PVL) Infarction of Periventricular White Matter
[DOC File]Rajiv Gandhi University of Health Sciences
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Consensus statement for diagnosis of subcortical small vessel disease. 1Gary A. Rosenberg, 2Anders Wallin, 3Joanna Wardlaw, 4Hugh S. Markus, 5Joan Montaner, 6Leslie ...
[DOCX File]Alzheimer's Association
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These two terms should not be applied to any white matter signal abnormality: they should be reserved for pervasive patterns of white matter disease (i.e. symmetric, homogeneous). White matter tracts : Macroscopic nerve fascicles of sufficient size to be visible on standard (T1,T2) or advanced (diffusion tensor) MR imaging, at least when abnormal.
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