Hypertrophic obstructive cardiomyopathy (HOCM) is thickening of the lower chambers of the heart. The septal muscle, which divides the right and left chambers, is especially affected. The condition can impede blood flow from the heart to the aorta. Cleveland Clinic physicians use a comprehensive approach to diagnose and treat patients with HOCM.
Cases in Hypertrophic Cardiomyopathy
Genetically determined heart muscle disease 60-70% caused by mutation in one of several sarcomere genes Sarcomere genes encode the contractile aparatus of the heart 11 genes with over 1500 mutations
www.escardio.org/guidelines European Heart Journal (2014):doi:10.1093/eurheartj/ehu284 Sudden Cardiac Death in HCM Annual incidence for cardiovascular death of 1–2% ...
Sex-dependent pathophysiological mechanisms in ...
HOCM ¼ hypertrophic obstructive cardiomyopathy; IVS ¼ ... disease and heart failure is markedly lower in women than in men, especially at a younger age.1 Sex differences in cardiac rhythm disorders are also seen, with some forms being more prevalent in men (eg, atrial ﬁbrillation [AF]2) and others in
tract obstruction and to slow the heart rate so that diastolic filling is enhanced 2,3,6,7 (Table 2). Al-though no data from long-term randomized, con-trolled trials are available, beta-blockers are gener-ally the initial choice for patients with symptomatic hypertrophic obstructive cardiomyopathy and are
Heart@Heart- version 29/11/2012 This information is a guide and does not replace the advice of your doctor Hypertrophic Cardiomyopathy (HCM) Hypertrophic cardiomyopathy (HCM) is an inherited condition that leads to abnormal thickening of the heart muscle, most often of the left ventricle (the main pumping chamber of the heart).
This disease is characterized by an abnormal thickening (hypertrophy) of one or several areas of the walls of the heart, usually of the left ventricle. Hypertrophic cardiomyopathy is also present in humans and is caused by a variety of genetic anomalies of the cardiac muscle proteins. In cats, this disease is more prevalent in Ragdolls, Maine
and challenging issues in the fields of heart failure, valvular heart disease, ischemic heart disease, cardiac electrophysiology, and hypertrophic cardiomyopathy. The hypertrophic cardiomyopathy session will be open to patients and interested members of the community, in addition to physicians and health care professionals,
Diagnosis and Treatment of Hypertrophic Cardiomyopathy (J Am Coll Cardiol 2011;XX:XX–XX). This pocket guideline is available on the World Wide Web sites of the American College of Cardiology (www.cardiosource. org) and the American Heart Association (my.americanheart.org).
Data Synthesis Hypertrophic cardiomyopathy is a relatively common genetic car- diac disease (1 :500 in the general population) that is heterogeneous with respect to disease- causing mutations, presentation, prognosis, and treatment strategies. Visibility at- tached to HCM relates largely to its recognition as the most common cause of sudden
Director, Division of Cardiology and Azrieli Heart Center Jewish General Hospital, McGill University President, Canadian Society of Echocardiography Disclosure: Small holding of GE Stock outside managed portfolio Utility of Echocardiography •Diagnosis –What is the disease •Severity & Prognostication –Is it relevant
Current Effectiveness and Risks of Isolated Septal ...
(HOCM). However, it is being challenged by a less-invasive alternative: alcohol septal ablation. This study examined the clinical effectiveness and risks of isolated septal myectomy for HOCM. Methods. From January 1994 to January 2005, 323 pa-tients underwent isolated septal myectomy (mean age 50 14 years, 53% male). Preoperative septal ...
2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy The Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC) ... Group on Grown-up Congenital Heart Disease, Working Group on Myocardial and Pericardial Diseases.
Fabry disease An X-linked disorder, caused by mutations of the alpha-galactosidase A gene.10 Fabry disease is a rare disease, affecting approximately 1 in 20,000–40,000 individuals.11,12 Cardiac involvement is common in Fabry disease and
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