ࡱ> C !! !!!!!!!!! ! ! ! !_ fbjbj 5t r=\r=\aF.)(--;NP<lNlNlN`Q`Q`QUlB`QB&r  &&&Do>>>>>>>$=GI> lNa2x;( aa>4=4=&&wAC5C5C5a4= &XHb&>C5a>C5C5 ">EL&p@&n>A0BT)K%Z+KKlN$|zC5J|||>>( |||BaaaaK|||||||||-> 9:  [COUNTRY] Ministry of Health Guidelines or Manual Community-based Management of (Severe) Acute Malnutrition FANTA-2, [DATE], Generic Version 1.00  About This Version The current version (v1.00) of these generic guidelines was compiled in May 2010.Please note that some recommendations on the management of severe acute malnutrition in children 659 months have been updated by WHO since 2010 and are not reflected in these files. FANTA recommends consulting the latest WHO guidelines and adapting these materials to take into account the WHO guidelines as well as national guidelines and local considerations. Contents [to be created after adaptation] LIST OF TABLES  TOC \h \z \t "Tableheader" \c HYPERLINK \l "_Toc259700173"Table 1. Independent Indicators and Clinical Signs of Acute Malnutrition with Cutoff for SAM and MAM for Children 6-59 Months  PAGEREF _Toc259700173 \h 4 HYPERLINK \l "_Toc259700174"Table 2. Admission and Discharge Criteria for CMAM for Children Under 5  PAGEREF _Toc259700174 \h 10 HYPERLINK \l "_Toc259700175"Table 3. Admission Criteria to CMAM for Children Under 5  PAGEREF _Toc259700175 \h 24 HYPERLINK \l "_Toc259700176"Table 4. Case Definitions of Medical Complications with SAM  PAGEREF _Toc259700176 \h 24 HYPERLINK \l "_Toc259700177"Table 5. First-Line Antibiotic Treatment: Amoxicillin, Three Times a Day for Seven Days (50-100 mg/kg Bodyweight/Day)  PAGEREF _Toc259700177 \h 31 HYPERLINK \l "_Toc259700178"Table 6. Malaria Treatment Based on Artesunate [AS 50 mg Tablet] and Amodiaquine [AQ 153 mg Tablet]  PAGEREF _Toc259700178 \h 31 HYPERLINK \l "_Toc259700179"Table 7. Antihelminthic Drug Dosage, Single Dose Albendazole [400 mg Tablet] or Mebendazole [500 mg Tablet]  PAGEREF _Toc259700179 \h 32 HYPERLINK \l "_Toc259700180"Table 8. Look-Up Table for Amounts of RUTF to Give to a Child per Day or Week Based on a Dose of 200 kcal/kg Bodyweight/Day Using 92 g Packets Containing 500 kcal  PAGEREF _Toc259700180 \h 33 HYPERLINK \l "_Toc259700181"Table 9. Criteria for Defining Failure to Respond to Treatment in Outpatient Care  PAGEREF _Toc259700181 \h 36 HYPERLINK \l "_Toc259700182"Table 10. Stabilisation Phase Volume of F75 for Persons with Severe Wasting  PAGEREF _Toc259700182 \h 44 HYPERLINK \l "_Toc259700183"Table 11. Stabilisation Phase Volume of F75 for Persons with Severe (+++) Bilateral Pitting Oedema  PAGEREF _Toc259700183 \h 45 HYPERLINK \l "_Toc259700184"Table 12. Transition Phase Look-Up Table for Amounts of RUTF to Give to a Child per Day Based on a Dose of 150 kcal/kg Bodyweight/Day Using 92 g Packets Containing 500 kcal  PAGEREF _Toc259700184 \h 47 HYPERLINK \l "_Toc259700185"Table 13. Transition Phase Look-Up Table for Volume of F100 per Feed if No RUTF is Taken, Based on 150 kcal/kg Bodyweight/Day  PAGEREF _Toc259700185 \h 48 HYPERLINK \l "_Toc259700186"Table 14. Rehabilitation Phase Look-Up Table for Amounts of RUTF to Give to a Child per Day Based on a Dose of +- 200 kcal/kg Bodyweight/Day Using 92 g Packets Containing 500 kcal  PAGEREF _Toc259700186 \h 53 HYPERLINK \l "_Toc259700187"Table 15. Rehabilitation Phase Look-Up Table for Volume of F100 per Feed if no RUTF is Taken Based on +- 200 kcal/kg Bodyweight/Day  PAGEREF _Toc259700187 \h 53 HYPERLINK \l "_Toc259700188"Table 16. Criteria for Defining Failure to Respond to Treatment in Inpatient Care  PAGEREF _Toc259700188 \h 55 HYPERLINK \l "_Toc259700189"Table 17. Look-Up Table for Maintenance Amounts of F100-Diluted (Severe Wasting) or F75 (Bilateral Pitting Oedema Until the Oedema is Resolved) for Breastfed Infants  PAGEREF _Toc259700189 \h 62 HYPERLINK \l "_Toc259700190"Table 18. Possible Difficulties Encountered by Mothers of Infants with SAM  PAGEREF _Toc259700190 \h 65 HYPERLINK \l "_Toc259700191"Table 19. Stabilisation Phase Look-Up Table for Volume of F100-Diluted (Severe Wasting) or F75 (Bilateral Pitting Oedema) for Non-Breastfed Infants Under 6 Months  PAGEREF _Toc259700191 \h 67 HYPERLINK \l "_Toc259700192"Table 20. Transition Phase Look-Up Table for Volume of F100-Diluted for Non-Breastfed Infants  PAGEREF _Toc259700192 \h 69 HYPERLINK \l "_Toc259700193"Table 21. Rehabilitation Phase Look-Up Table for Volume of F100-Diluted for Non-Breastfed Infants  PAGEREF _Toc259700193 \h 70 HYPERLINK \l "_Toc259700194"Table 22. Dietary Requirements of Adolescents and Adults in the Stabilisation Phase  PAGEREF _Toc259700194 \h 74 HYPERLINK \l "_Toc259700195"Table 23. Summary Entry and Exit Categories for Individual and Service Monitoring for Children 6-59 Months  PAGEREF _Toc259700195 \h 81 HYPERLINK \l "_Toc259700196"Table 24. Cutoffs for CMAM Outcome Indicators as per Sphere Minimum Standards  PAGEREF _Toc259700196 \h 88  LIST OF FIGURES  TOC \h \z \t "Figureheader" \c HYPERLINK \l "_Toc259110411"Figure 1: Components of Community-based Management of Acute Malnutrition (CMAM)  PAGEREF _Toc259110411 \h 11 HYPERLINK \l "_Toc259110412"Figure 2. Stages in Community Outreach  PAGEREF _Toc259110412 \h 21 HYPERLINK \l "_Toc259110413"Figure 3. Admission and Treatment Flow Chart, Children 6-59 Months with SAM  PAGEREF _Toc259110413 \h 29 HYPERLINK \l "_Toc259110414"Figure 4. Overview Treatment of Children with SAM: WHO 10-Step According to the WHO 1999 Treatment Protocol  PAGEREF _Toc259110414 \h 42 HYPERLINK \l "_Toc259110415"Figure 5. Supplementary Suckling Technique  PAGEREF _Toc259110415 \h 64  LIST OF BOXES  TOC \h \z \t "Text Box Title" \c HYPERLINK \l "_Toc259656939"Box 1. Summary of Steps in Community Outreach  PAGEREF _Toc259656939 \h 14 HYPERLINK \l "_Toc259656940"Box 2. Summary of Community Assessment Tools  PAGEREF _Toc259656940 \h 15 HYPERLINK "file:///C:\\Documents%20and%20Settings\\aed%20user\\Desktop\\GOSS_IMSAM_Guidelines_April20.docx" \l "_Toc259656941"Box 3. Community Screening and Referral for Treatment  PAGEREF _Toc259656941 \h 19 HYPERLINK "file:///C:\\Documents%20and%20Settings\\aed%20user\\Desktop\\GOSS_IMSAM_Guidelines_April20.docx" \l "_Toc259656942"Box 4. Admission and Initial Treatment Procedures  PAGEREF _Toc259656942 \h 27 HYPERLINK \l "_Toc259656943"Box 5. Appetite Test  PAGEREF _Toc259656943 \h 28 HYPERLINK \l "_Toc259656944"Box 6. Examples of Frequent Causes of Failure to Respond to Treatment in Outpatient Care  PAGEREF _Toc259656944 \h 37 HYPERLINK \l "_Toc259656945"Box 7. Admission Criteria for Inpatient Care  PAGEREF _Toc259656945 \h 40 HYPERLINK \l "_Toc259656946"Box 8. Summary of Reasons for Using a NGT to Feed the Child During Stabilisation  PAGEREF _Toc259656946 \h 43 HYPERLINK \l "_Toc259656947"Box 9. Discharge Criteria from Inpatient Care Rehabilitation Phase  PAGEREF _Toc259656947 \h 54 HYPERLINK "file:///C:\\Documents%20and%20Settings\\aed%20user\\Desktop\\GOSS_IMSAM_Guidelines_April20.docx" \l "_Toc259656948"Box 10. Frequent Causes of Failure to Respond to Treatment in Inpatient Care  PAGEREF _Toc259656948 \h 57 HYPERLINK \l "_Toc259656949"Box 11. Admission Criteria for Inpatient Care for the Management of SAM in Older Age Groups  PAGEREF _Toc259656949 \h 72  Acknowledgements These guidelines were developed in partnership with the United States Agency for International Developments Food and Nutrition Technical Assistance II Project (FANTA-2). We acknowledge the United Nations Childrens Fund (UNICEF) for ________. We acknowledge the World Health Organization (WHO) for _______. We also recognise with special gratitude the significant contribution of ________ , which provided financial support for the coordination of meetings and technical reviews during the development of the guidelines. The guidelines were largely constructed from World Health Organisation (WHO) scientific recommendations and globally recognized best practices. The guidelines were validated with the recommendations of both local and international health and nutrition organisations that participate in the [____________ Technical Working Group]. Their expert presence in the field within [COUNTRY] has greatly informed the final product. [Add other acknowledgments as appropriate] Materials from the following sources are also gratefully acknowledged: WHO. 1999. Management of severe malnutrition: a manual for physicians and other senior health workers. Geneva: WHO. WHO. 2002. Training course on the management of severe malnutrition. Geneva: WHO. Golden, M.H., and Y. Grellety. 2006. Guidelines for the management of the severely malnourished. (Draft) Valid International. 2006. Community-based Therapeutic Care. A Field Manual. 1st edition. Oxford, UK: Valid International. Concern Worldwide, FANTA, UNICEF and Valid International. 2008. Training Guide for Community-Based Management of Acute Malnutrition (CMAM). Washington, DC: FANTA FHI360. Prof. M. Golden and Dr. Y. Grellety kindly permitted to copy their original material on the clinical management of severe acute malnutrition with medical complications in inpatient care. This material is reproduced with the understanding that it can be taken and used by national governments of developing countries and their teaching institutions without payment of any fees or the need to obtain further permission, provided that the material is not edited, abstracted or altered. Those from developed countries and those who wish to abstract or edit the material should seek permission from the copyright holders. [Add other acknowledgments as appropriate] Acronyms and Abbreviations [Add or remove acronyms and abbreviations as appropriate] < Less than d" Less than or equal to > Greater than e" Greater than or equal to g Microgram(s) ACT Artemisinin-based combination therapy AIDS Acquired immune deficiency syndrome AQ Amodiaquine ART Antiretroviral therapy AS Artesunate AWG Average weight gain BMI Body mass index BPHNS Basic Package of Health and Nutrition Services CBO Community-based organisation CD4 Cluster of differentiation 4 CHW Community health worker cm Centimetre(s) CMAM Community-Based Management of (Severe) Acute Malnutrition CMV Combined mineral and vitamin complex CSB Corn-soy blend CSF Cerebro-spinal fluid dl Decilitre(s) ENA Essential Nutrition Actions EPI Expanded programme of immunisation F100 Formula 100 therapeutic milk F75 Formula 75 therapeutic milk g Gram(s) Guidelines [Interim National Guidelines on the Community-based Management of Severe Acute Malnutrition] Hb Haemoglobin HFA Height-for-age HIV Human immunodeficiency virus HMIS Health management information system IECHC Integrated essential child health care policy IM Intramuscular IMCI Integrated Management of Childhood Illnesses IQ Intelligence quotient IU International unit(s) IV Intravenous IYCF Infant and young child feeding KAP Knowledge, Attitudes and Practice kcal Kilocalorie(s) kg Kilogram(s) L Litre(s) LOS Length of stay M&R Monitoring and reporting MAM Moderate acute malnutrition MDG Millennium Development Goal mg Milligram(s) mgmt Management ml Millilitre(s) mm Millimetre(s) mmol Millimole(s) MOH Ministry of Health mOsmol Milliosmol(s) MUAC Mid-upper arm circumference NCHS National Centre for Health Statistics NGO Nongovernmental organisation NGT Nasogastric tube OPD Outpatient department ORS Oral rehydration solution ORT Oral rehydration therapy PCV Packed cell volume [HC] [Health Centre] [HP] [Health Post] PLHIV People living with HIV PMTCT Prevention of mother-to-child transmission of HIV RDA Recommended Daily Allowance ReSoMal Rehydration solution for malnutrition RUTF Ready-to-use therapeutic food SAM Severe acute malnutrition SD Standard deviation(s) SFP Supplementary feeding programme Sphere Standards The Sphere Project 2010 Humanitarian Charter and Minimum Standards in Disaster Response SWOT Strengths, weaknesses, opportunities and threats TB Tuberculosis TOR Terms of reference TWG Technical working group UN/SCN United Nations Standing Committee on Nutrition UNFPA United Nations Population Fund UNICEF United Nations Childrens Fund US United States WFA Weight-for-age WFH Weight-for-height WFP World Food Programme WHO standards World Health Organisation 2006 Child Growth Standards WHO World Health Organisation 1. Introduction These interim national guidelines for [COUNTRY] address the community-based management of (severe) acute malnutrition (CMAM) in children under 5, and include community outreach, outpatient care and inpatient care for the management of severe acute malnutrition (SAM). Community outreach is an essential part of the CMAM approach since the success of the service relies on early detection and referral of cases with SAM through community participation, with an aim to reach children early in the development of the acute malnutrition condition. The Interim National Guidelines for the Community-based Management of Acute Malnutrition (the Guidelines) provide practical and easy-to-follow guidance based on current evidence and best practices in the community-based management of SAM. Job aids will accompany the guidelines. The Guidelines seek to improve the community-based management of SAM in children 6-59 months with medical complications in inpatient care and without medical complications in outpatient care, as these children do not require hospitalisation but can be treated at the community level. Infants under 6 months with SAM follow a specific treatment protocol in inpatient care only. A separate paragraph addresses the management of SAM in inpatient care in older age groups (i.e., older children ages 5-9 years, adolescents ages 10-18 years, adults over 18 years). SAM occurs as a primary disorder in these age groups in extreme conditions of privation and famine, or in association with other illnesses. In the latter case, both the primary illness and the acute malnutrition must be treated. Adherence to the Guidelines will contribute significantly towards improving the quality of the management of SAM as measured by increases in recovery rates, reductions in case fatality and defaulter and non-recovery rates, and increases in service access and utilisation (coverage). They will contribute to improved standardised treatment and standardised monitoring and reporting (M&R). They can also be used as a mobilising force for addressing SAM and strengthening capacities. They should facilitate the integration of the management of SAM into the primary health care system, while compliance will contribute in the overall reduction of child mortality in [COUNTRY]. The Guidelines for CMAM are intended to be used by health and nutrition managers and health care providers working at different levels of health and nutrition service provision in [COUNTRY]. 1.1 Acute Malnutrition as a Form of Undernutrition 1.1.1 What Is Undernutrition Undernutrition is a composite form of a deficiency in nutrient intake and/or absorption in the body. There are four forms of undernutrition: acute malnutrition, stunting, underweight and micronutrient deficiencies. The four forms can appear isolated or in combination but most often they overlap in one child or in a population. Undernutrition is identified through anthropometric indicators and clinical signs. Nutrition indicators are an interpretation of nutrition indices based on cutoff points. They measure the clinical phenomena of undernutrition and are used for making a judgment or assessment. There are four common anthropometric nutrition indicators: mid-upper arm circumference (MUAC) and weight-for-height (WFH), which are used to assess wasting; height-for-age (HFA), which is used to assess stunting; and weight-for-age (WFA), which is used to assess underweight. The presence of bilateral pitting oedema is a clinical sign indicating SAM. 1.1.2 What is Acute Malnutrition Acute malnutrition is caused by a decrease in food consumption and/or illness resulting in bilateral pitting oedema or sudden weight loss. It is defined by the presence of bilateral pitting oedema or wasting. Anorexia, or poor appetite, and medical complications are clinical signs indicating or aggravating the severity of acute malnutrition. There are two forms of acute malnutrition: SAM, or severe acute malnutrition, is defined by the presence of bilateral pitting oedema or severe wasting, and other clinical signs such as poor appetite. A child with SAM is highly vulnerable and has a high risk of death. MAM, or moderate acute malnutrition, is defined by moderate wasting. The following terms are used to describe the clinical manifestations of SAM: Marasmus, characterised by severe wasting of fat and muscle, which the body breaks down for energy, leaving skin and bones Kwashiorkor, characterised essentially by bilateral pitting oedema (usually starting in the feet and legs), accompanied by a skin rash and/or changes in hair colour (greyish or reddish) Marasmic kwashiorkor, characterized by a combination of severe wasting and bilateral pitting oedema 1.1.3 Assessing Acute Malnutrition Bilateral pitting oedema is a clinical manifestation of acute malnutrition caused by an abnormal infiltration and excess accumulation of serous fluid in connective tissue or in a serous cavity. Bilateral pitting oedema is verified when thumb pressure applied on top of both feet for three seconds leaves a pit (indentation) in the foot after the thumb is lifted. Wasting in children 6-59 months is assessed by a low MUAC measurement and/or a low WFH using the WHO 2006 child growth standards (WHO standards). MUAC involves measuring the circumference of a childs left mid-upper arm. MUAC < 115 millimetres (mm) for children ages 6-59 months indicates SAM. MUAC e" 115 mm and < 125 mm for children ages 6-59 months indicates MAM. MUAC is a better indicator of mortality risk associated with acute malnutrition than WFH z-score. MUAC is used for children 6 months and older. A child s date of birth or age is assessed based on the mother or caregivers proof or recall, and no proxy of height to assess age is used for infants and young children. The WFH index shows how a childs weight compares to the weight of a child of the same height and sex using the WHO standards. A WFH standard deviation (SD) below -2 z-score of the median (WFH < -2 z-score) of the WHO standards indicates wasting. Severe wasting is indicated by a WFH < -3 z-score. Moderate wasting is indicated by a WFH e" -3 and < -2 z-score. (Refer to anthropometry look-up tables in Annex ) Acute malnutrition in infants under 6 months is identified by the presence of bilateral pitting oedema and/or visible wasting. Also WFH can be used, as explained above for children 6-59 months as the anthropometry look-up tables start from 45 cm length. Research is ongoing to identify cutoffs for MUAC for infants 2-5 months. In addition, infants at high risk of wasting will receive community-based care to support infant and young child feeding (IYCF) and maternal care practices to address the related inadequate feeding or care of the infant or lactating mother. Table 1. Independent Indicators and Clinical Signs of Acute Malnutrition with Cutoff for SAM and MAM for Children 6-59 Months  Bilateral pitting oedemaMUACWFH z-scoreSAM:Present< 115 mm< -3MAM:Not presente" 115 mm and < 125 mme" -3 and < -2 In most cases, anthropometric measurements alone can confirm the clinical diagnosis of SAM and MAM (see Table 1). Clinical signs are essential to assess because they will indicate the severity of illness. In the presence of anthropometric confirmation of SAM, it is essential to assess the following clinical signs: Anorexia, poor appetite Intractable vomiting Convulsions Lethargy, not alert Unconsciousness Hypoglycaemia High feverHypothermia Severe dehydration Persistent diarrhoea Lower respiratory tract infection Severe anaemia Eye signs of vitamin A deficiency Skin lesion  Other clinical signs of wasting may be present without the anthropometric confirmation, e.g., skin on the buttocks has a baggy pants look. 1.1.4 Pathophysiology of SAM There are approximately 40 known essential nutrients which, when not available in the right balance, result in undernutrition and increase the risk of severe illness and likelihood of death in young children. The nature and consequences of deficiencies of these essential nutrients is determined by the bodys physiological response to their deprivation. The essential nutrients have been classified into Type 1 (functional) nutrients and Type 2 (growth) nutrients. Examples of Type 1 nutrients are iron, iodine, vitamin C and vitamin A. In response to Type 1 nutrient deficiency, childrens bodies continue to grow using up the stored nutrient, eventually leading to tissue depletion, metabolic dysfunction, and consequent ill health. Examples of Type 1 nutrient deficiency include iron deficiency anaemia and scurvy. Even though the illness resulting from Type 1 nutrient deficiency has characteristic signs and symptoms, the deficiency is not identified through anthropometric measurements. Examples of Type 2 nutrients are potassium, magnesium, zinc, selenium and amino acids. In response to a Type 2 nutrient deficiency, the body stops growing and repairing tissue to conserve nutrients, and the body breaks down its own tissue to make the nutrients available. While Type 2 nutrient deficiency can be identified through anthropometric measurements (wasting and stunting), identifying the deficit nutrients is complex because deficiency in one Type 2 nutrient is often accompanied by deficiency in other Type 2 nutrients. Undernutrition accompanied by infection can operate in a self-reinforcing downward cycle of tissue depletion and lowered resistance to disease. The pathophysiological responses to nutrient depletion place children with SAM at increased risk of life-threatening complications that lead to increased risk of death. Therefore, successful management of SAM in children requires systematic medical treatment of underlying infections and a dietary treatment or rehabilitation with specially formulated therapeutic foods, such as F75 and F100 milk, or a ready-to-use therapeutic food (RUTF). Therapeutic foods have the correct balance of Type 1 and Type 2 nutrients and a high nutrient density and bioavailability. The treatment aims to restore the metabolism through correction of electrolyte balance, reversal of metabolic abnormalities, restoring the organ functions and provision of nutrients for catch-up of growth. Because of the pathophysiological changes that accompany SAM, these children often do not present typical clinical signs of infection that sick children without SAM have when they are ill, such as fever. Consequently, children with SAM need to be provided with systematic medical treatment for underlying infections. Treatment protocols for children with SAM for some medical complications, such as dehydration or shock, differ from the classical treatment protocols for ill children without SAM. Misdiagnosis of medical complications, inappropriate treatment and feeding of children with SAM contributes to slow convalescence and increased risk of death, thus adherence to these Guidelines in their entirety is critical. 1.2 The Burden of Acute Malnutrition 1.2.1 Burden of Acute Malnutrition at the Global Level Childhood undernutrition is an underlying cause of 35 percent of deaths among children under 5 in the developing world. According to the 2008 Lancet Series on Maternal and Child Undernutrition, SAM is one of the most important contributing causes of childhood mortality. An estimated 19 million children under 5 suffer from SAM, with half a million dying directly because of SAM each year. These numbers do not include children suffering from bilateral pitting oedema, which is the most lethal form of acute malnutrition. Undernutrition also has a lasting effect on its survivors, reducing their income potential by leaving them less able to learn or perform physical labour and trapping them in a generational cycle of poverty. Undernutrition is responsible for 11 percent of disability adjusted life years among young children worldwide. Severe wasting during the first 24 months of life leads to a loss of up to 18 points ofan individual's expected intelligence quotient score. The negative impact of undernutritionon the physical and mental potential of the population diminishes national productivity, costing countries as much as 3 percent of their gross domestic product. The international aid community has traditionally considered high rates of acute malnutrition the result of crises such as drought and conflict rather than a chronic problem with developmental causes. As a public health concern, acute malnutrition has therefore mainly been the target of stand-alone, emergency nutrition interventions. While humanitarian emergencies do cause widespread undernutrition, in reality, the majority of acutely malnourished children live in stable countries not currently experiencing a crisis. They are undernourished because of complex behavioural and environmental factors rather than a temporary loss of access to food due to an emergency. Addressing the majority of the global burden of undernutrition requires that nutrition programmes be integrated into health systems in sustainable ways. In 2000, United Nations member states adopted the Millennium Declaration, committing themselves to reducing poverty and improving the lives of the world's poorest citizens by 2015.A series of eight goals, known as the Millennium Development Goals (MDGs), lays out an action plan to reduce poverty, disease and hunger worldwide. MDG One is to eradicate extreme poverty and hunger by 2015. MDG Four is to reduce child mortality by two-thirds by 2015. As this deadline fast approaches, achieving these goals is further threatened by global food price increases, inadequate mother and child feeding and care practices, and civil strife and environmental disasters. Investments by the international community and national governments in evidence-based, high-impact nutrition interventions to prevent and treat acute malnutrition are therefore critical. 1.2.2 Burden of Acute Malnutrition in [COUNTRY] This section gives an overview of the current nutrition situation in your country. You can also give some background to give readers a better understanding of the events or aspects contributing to the countrys nutrition situation. Some of the aspects to consider writing about include: Health conditions Maternal and child feeding and care practices Breastfeeding practices and quality of complementary foods Food insecurity Dietary diversity Food prescriptions/taboos Water, hygiene and sanitation Poverty Illiteracy Civil strife Environmental shocks (e.g., floods and droughts) Percent prevalence of wasting Percent prevalence of stunting Vitamin or mineral deficiencies Percent of children under 5 currently receiving Vitamin A supplementation Percent of children fully immunized Rates of communicable diseases most associated with undernutrition (e.g., fever, acute respiratory infection, and diarrhoea Current health care system and infrastructure Be sure to cite your sources of information. An example is shown in Box 1 on the following page.  1.3 Principles of the Community-based Management of Acute Malnutrition (CMAM) For a number of years, the main intervention for the treatment of SAM globally has been inpatient care provided either in paediatric wards or specialised therapeutic feeding centres, and next following the WHO 1999 treatment protocol for SAM. A new approach was developed following the invention and use of RUTF, whereby children 6-59 months with SAM with good appetite and without medical complications can start treatment for SAM in outpatient care (rather than inpatient care) and continue drug and dietary treatment in the home. Meanwhile, children with SAM with medical complications are admitted to inpatient care but are referred to outpatient care as soon as their medical complication is resolving, and continue treatment until full recovery in outpatient care and their home. Table 1 shows the classification of SAM that is used in the community-based management of SAM (CMAM) approach. The use of MUAC as an independent criterion for SAM for children is also approved and makes detection of SAM in the community and at the health facility simple and treatment more effective. Evidence accumulated from early studies and field practice in Malawi, Ethiopia and Sudan, followed by more evidence from other countries, has led to the decentralised community-based approach that makes a distinction in severity of the condition of the child with SAM. The majority of children with SAM over 6 months who have appetite and no medical complications can be treated in outpatient care without the need to have residential treatment. Small numbers of children with SAM who have poor appetite or developed medical complications need inpatient care. The approach is built upon a strong community outreach element for community mobilisation and early case-finding and referral, which in turn increases service access and utilisation (coverage) and decreases the risk of children developing medical complications. As evidence shows, the impact of this intervention contributes considerably to reducing mortality associated with SAM. The following is a brief overview of the CMAM approach based on a few key principles. 1.3.1 Community Outreach Good community outreach is essential to make sure that undernourished children are detected early and referred for treatment. The aim is to detect and start the treatment of SAM before the onset of life-threatening complications. Community outreach also mobilises communities; it raises awareness of the burden of malnutrition and aims of services, and builds support for them. Moreover, it strengthens the communitys awareness of causes, signs and treatment of acute malnutrition, and promotes health and nutrition behaviour change and improved hygiene. Through community outreach, health care providers can better understand the needs of the local community and the factors that may act as barriers to accessing care, while promoting and supporting infant and child nutrition and care practices in the communities to prevent malnutrition. It is important to link community outreach for acute malnutrition with existing community health and nutrition outreach systems or initiatives, and further strengthen the outreach system. 1.3.2 Outpatient Care for Children 6-59 Months A nutrition and medical assessment carried out by a qualified health care provider will determine if a child 6-59 months with SAM has good appetite (passed the appetite test) and no medical complications, and can thus be treated in outpatient care (see Table 2 for criteria). The child will receive systematic medication according to the treatment protocol, as well as a home ration of RUTF equivalent to about 200 kilocalories per kilogram of bodyweight per day (kcal/kg bodyweight/day) to last until the next health visit (usually weekly). Monitoring of the clinical condition is managed at the health facility, mobile clinic or decentralised health outreach points, and treatment is continued at home. The child returns weekly to the health facility or outreach point for follow-up of the health and nutrition progress and replenishing RUTF supplies until full recovery. Outpatient care is provided to the majority of children with SAM, who have appetite and are without medical complications. Outpatient care is also provided to children with SAM and medical complications after their treatment in inpatient care to continue their rehabilitation in the home. 1.3.3 Inpatient Care Anorexia or poor appetite, severity of illness and presence of medical complications are the main determinants for providing inpatient care to children 6-59 months with SAM (see Table 2 for criteria). A small proportion of children with SAM have poor appetite or will develop medical complications that require intensive medical and nutrition care until their medical condition has stabilised, the medical complication is resolving and their appetite has returned. Children requiring inpatient care for stabilisation will be treated in paediatric wards or health facilities that provide 24-hour inpatient care for SAM with medical complications by skilled health care providers. CMAM inpatient care treatment protocols are adapted from the WHO 1999, 2007 and 2009 protocols for the management of SAM and refer the child 6-59 months with SAM to outpatient care as soon as the childs severe bilateral pitting oedema begins reducing, the medical condition is resolving and/or appetite has returned. The child will then continue treatment in his/her home and receive monitoring and RUTF in outpatient care on a weekly basis until full recovery. In rare situations, children 6-59 months remain in inpatient care until full recovery. All infants under 6 months with SAM as well as other age groups with SAM are treated in inpatient care until full recovery. 1.3.4 The management of MAM in Children 6-59 Months and Pregnant and Lactating Women The management of MAM in children 6-59 months and other vulnerable groups consists of providing a fortified food supplement, antihelminthic drug, and vitamin and mineral supplementation, and the monitoring of health and nutritional status. A commonly known approach in food-insecure environments or emergencies is targeted supplementary feeding for children 6-59 months and vulnerable individuals identified with MAM. Vulnerable groups with MAM might include pregnant women and lactating women with infants under 6 months, individuals with special needs such as people living with HIV (PLHIV), people with tuberculosis (TB) and the elderly. Specific anthropometric criteria for entry and discharge are used. Also, children with SAM should benefit after recovery from a dietary supplement and regular monitoring. The dietary requirements and programmatic evidence for the management of MAM are under revision at the global level and improved guidance is expected shortly. (Note: In a next step, these Guidelines will include the community-based management of MAM reflecting the use of the WHO standards, new evidence and improved best practices). Table 2. Admission and Discharge Criteria for CMAM for Children Under 5 Inpatient Care  Outpatient Care ADMISSION CRITERIA CHILDREN 6-59 MONTHS  FORMCHECKBOX  Bilateral pitting oedema +++  CHILDREN 6-59 MONTHS  FORMCHECKBOX  Bilateral pitting oedema + and ++ OR  FORMCHECKBOX  Any grade of bilateral pitting oedema with severe wasting OR  FORMCHECKBOX  Severe wasting (MUAC < 115 mm or WFH < -3 z-score) AND Appetite test passed No medical complication Child clinically well and alert OR  FORMCHECKBOX  SAM with any of the following medical complications:Anorexia, poor appetite Intractable vomiting Convulsions Lethargy, not alert Unconsciousness Hypoglycaemia High fever Hypothermia Severe dehydration Persistent diarrhoea Lower respiratory tract infection Severe anaemia Eye signs of vitamin A deficiency Skin lesion OR  FORMCHECKBOX  Referred from outpatient care according to action protocol INFANTS < 6 MONTHS  FORMCHECKBOX  Bilateral pitting oedema OR  FORMCHECKBOX  Visible wasting - Includes infants with SAM e" 6 months and < 4 kg REFERRAL/DISCHARGE CRITERIA CHILDREN 6-59 MONTHS  FORMCHECKBOX  Referred to outpatient care: Appetite returned (passed appetite test) Medical complication resolving Severe bilateral pitting oedema decreasing Child clinically well and alert (If admitted due to bilateral pitting oedema and severe wasting: criterion for referral is bilateral pitting oedema resolved)  FORMCHECKBOX  Discharged cured (special cases): 15 percent weight gain maintained for two consecutive days Oedema free for two consecutive weeks Child clinically well and alert INFANTS < 6 MONTHS  FORMCHECKBOX  Discharged cured: If successful re-lactation and appropriate weight gain maintained (minimum 20 g per day on breastfeeding alone for five days) and infant clinically well and alert (if infant has no access to breastfeeding, see other guidance for non-breastfed children on replacement feeding)  CHILDREN 6-59 MONTHS  FORMCHECKBOX  Discharged cured: 15 percent weight gain maintained for two consecutive visits (of admission weight or weight free of oedema) Oedema free for two consecutive visits Child clinically well and alert Children are referred to receive supplementary feeding if available Figure 1: Components of Community-based Management of Acute Malnutrition (CMAM)        1.4 CMAM in the Context of [COUNTRY] 1.4.1 Operational Practices of CMAM to Date Geographic mapping of services and programmes focusing on the management of SAM in [COUNTRY] [exists or not]. Overall, to date, the capacity to manage acute malnutrition across countries can be characterised as [INSERT, e.g., strong, weak, fragmented, non-existent]. Ministry of Health (MOH) and a number of nongovernmental organizations (NGOs) currently support acute malnutrition intervention programmes following a facility- or community-based approach with differing treatment protocols operating integrated or in parallel to national health systems. [INSERT number of counties where CMAM has been implemented and expanded, as well as talk about coverage]. (Country-specific lessons from implementing CMAM will be reviewed and may lead to recommending adaptations to these interim Guidelines). [INSERT information about other nutrition programmes, such as the Essential Nutrition Actions (ENA), accelerated child survival initiatives, growth monitoring and micronutrient supplementation, as part of the basic package of health, and where they are implemented.] 1.4.2. Policy Framework for CMAM  1.4.3 National Strategy and Implementation for CMAM  For example: the overall objective of integrating and scaling up CMAM in [COUNTRY] is to reduce under-5 morbidity and mortality rates related to acute malnutrition through increased access to quality services for the management of acute malnutrition. 2. Community Outreach Community outreach is a critical component in CMAM and can be undertaken on its own or integrated into community health outreach activities, further strengthening and supporting existing health outreach systems. The main aims of community outreach for CMAM include: Empowering the community through increasing knowledge of causes, types, identification and treatment of SAM; promoting health and nutrition behaviour change; and involving the community in planning and implementing the services Increasing service access and uptake (coverage) for the management of SAM Conducting and strengthening early case-finding and referral of new SAM cases and follow-up of problem cases Strengthening the responsibility of the community health committee to encourage sustainability and ownership Community outreach increases knowledge and acceptance of CMAM services and enables behaviour change in care practices for children with SAM. It also provides a feedback loop that enables nutrition workers and health care providers to understand the constraints that might hinder effective provision of care in outpatient and inpatient care settings. Community outreach should form one of the important initial steps towards development of a successful programme for the management of SAM. Community outreach is a continuous process that contributes toward strengthening case-finding, referral and follow-up of children with SAM in the community. It should aid in effective monitoring of screening activities to increase programme coverage and ensure that the majority of children with SAM receive the appropriate care they require. Ultimately, communities are empowered and are better able to fulfil their roles and obligations related to the care of malnourished children. Box 1. Summary of Steps in Community Outreach Planning for Community Outreach Step 1: Conducting a Community Assessment Step 2: Formulating a Community Outreach Strategy Step 3: Developing Messages and Materials Step 4: Conducting Training on Community Outreach Implementation of Community Outreach Step 5: Conducting Community Mobilisation Step 6: Conducting Case-Finding and Referral of New Cases with SAM Step 7: Conducting Home Visits of Problem Cases Step 8: Linking with Other Community Services, Programmes and Initiatives  Step 1: Conducting a Community Assessment An assessment of the community is the first step in the planning of community outreach for CMAM. The assessment is key to determining the factors that are likely to impact both service delivery and demand. The CMAM outreach coordinator (i.e., one focal point or a team consisting of the health outreach coordinator, community health nurse, members of the district health department) should conduct the assessment with the objective of answering two main questions: What aspects of the community are likely to affect the demand for the CMAM services? How can community outreach be organised to meet the demand for the CMAM services most effectively? The community assessment comprises the following activities: Engage the community in a participatory discussion on its understanding of acute malnutrition and its causes, the magnitude of the problem, and possible solutions. This may be done through local social structures or meetings or during child survival outreach services. Groups to engage with include key community leaders, elders and other influential people, mothers, fathers, caregivers, and traditional health professionals. Identify local terms for malnutrition, perceived causes and common local solutions. Gather information on ethnic, social or religious groups, and the most vulnerable groups (e.g., single mothers, orphans and vulnerable children, PLHIV). Identify existing community systems and structures, and community-based organisations (CBOs) or informal groups (e.g., faith-based groups, youth groups, womens groups). Identify formal and informal channels of communication that are known to be effective. Identify health attitudes and health-seeking behaviours. Identify available services and resources for mother and child care. Review Knowledge, Attitudes and Practices (KAP) and coverage surveys or other sociological studies conducted on health-seeking, care and feeding practices and behaviours. Map (and/or list) the information that is gathered. Prior to the community visits, key questions will be identified to guide the community discussions (see example in Annex 22. Community Assessment Questionnaire and Tools). Information that is gathered during the community assessment is consolidated to facilitate ease of understanding and utilisation. A variety of tools will be used to simplify this process (see Box 2). This information will be later used in methods to evaluate the service access and utilisation (coverage). Box 2. Summary of Community Assessment Tools 1. Geographic community map Plot the presence of NGOs, CBOs, community health committees and community volunteer networks on a geographic representation of the catchment area. Add geographic and demographic information and community structures (e.g., road, river, canyon, marketplace, mosque, health facility, water source). Represent the information on a hand drawn map on, e.g., a flip chart. 2. Matrix of community actors and their initiatives, target population and coverage List NGOs, CBOs, community committees and community volunteer networks by community and/or assessment area in a matrix. List the various community actors with their initiatives and/or activities, target population and coverage. 3. SWOT analysis for community participation and outreach for CMAM Conduct a strengths, weaknesses, opportunities and threats (SWOT) analysis consisting of the identified strengths and weaknesses of the current situation and the identified opportunities and threats for future community participation and outreach strategies and activities for CMAM. Plot the analysis on a matrix. 4. Matrix of key perceptions and practices on health and nutrition List key perceptions and practices impacting health and nutritional status and implications for community outreach strategies and activities for CMAM. Identify potential ways to appropriately address the identified key issues. 5. Matrix of potential community outreach workers for CMAM List community outreach workers, including various extension workers and volunteers with potential for involvement in community outreach for CMAM. Identify the strengths and weaknesses of involving these actors for community outreach for CMAM. 6. Matrix of community actors selected for community participation and outreach for CMAM List the various community actors that are identified to be used for community outreach activities and coordination/supervision, outlining respective responsibilities at start up and during the implementation phase.  Step 2: Formulating a Community Outreach Strategy Outreach for CMAM will be tailored to the context in which it is being implemented and is designed and planned in participation with the communities. The Government of [COUNTRY], state/region MOH or district health department will take the lead role and decide how to strategise and roll out CMAM activities. The CMAM outreach coordinator will: Negotiate for the adoption of CMAM to manage acute malnutrition in the community Identify (and agree upon) the best mechanisms for community outreach: Outreach workers (e.g., community health workers (CHWs), extension workers of various programmes, volunteers who are respected in the community) Sites and/or the type of screening that will be conducted (e.g., house-to-house, home visits, regular gatherings in the community) Discuss and develop clear definitions of roles and responsibilities for the outreach worker to ensure that children with acute malnutrition are identified and referred for treatment and subsequently followed up in their homes as needed; outreach workers will also provide feedback to the health facilities on problems related to the childrens home environment Strategies to identify and refer children with acute malnutrition could include: House-to-house visits Screening during national campaigns, at any contact with the primary health service, at health facilities and any other health outreach points Screening at community activities and services (e.g., community meetings, markets, activities of CBOs, other available opportunities) Self referrals from the community Step 3: Developing Messages and Materials The use of standardised messages adapted to different audiences will facilitate uniform and accurate information sharing on malnutrition, its causes and treatment, and places where treatment services are available. Pamphlets, local radio and television messages, and meetings with community and religious leaders provide essential information about the service/programme aims, methods and actors. In particular, communities should understand what the service/programme will mean to them in practice: what it will do, who is eligible, where it will operate, who will implement it, how to access it and what the overall benefit of the service/programme is to the community. Activities at this stage could include: Developing messages for different audiences and messaging tools (e.g., pamphlet, radio message, letter) that will provide information about CMAM services in the community (see Annex 1. Community Outreach Messages) Developing an orientation and dissemination plan on community mobilisation for key members of the health system (e.g., health care providers, health extension workers or other support staff, managers and supervisors) and outreach workers Developing a training plan for outreach workers on active screening for referral and home visits in the communities Step 4: Conducting Training on Community Outreach Training for coordinators, planners and supervisors of community outreach could include: Outreach strategies Basic information on the causes, types, identification and treatment of malnutrition Objectives and target population for the management of SAM Practice in the identification of bilateral pitting oedema and the use of MUAC and WFH measurements Case referral and follow-up strategies and issues Health and nutrition education and strategy Community mobilisation and how to engage with the communities and share information Training and supervising community outreach workers Roles and responsibilities of community outreach coordinators and workers Training for community outreach workers could include: Basic information on the causes and types of malnutrition, and its identification and treatment Objectives and target population for the management of SAM Practice in the identification of bilateral pitting oedema and the use of MUAC and WFH measurements CMAM services, sites and referral for treatment Follow-up strategies and issues Health and nutrition education Community mobilisation and how to engage with the communities and share information Roles and responsibilities of community outreach workers Step 5: Conducting Community Mobilisation Community mobilisation aims to raise awareness of the service/programme. It promotes understanding and service access and use and lays the foundations for community ownership. Community mobilisation is an ongoing activity, not a one-time-only event. Much of the community interaction takes place early in the programme, but should be continually reinforced throughout the implementation phase to be effective. Community mobilisation should be seen as a process of constant dialogue in which communities can periodically voice their views and suggest alternative courses of action. The aim is to continue a dialogue with community members, address concerns, encourage positive behaviour changes and share success stories. When the community outreach strategy for CMAM includes volunteers, the community mobilisation activity should engage community leaders and community health committees to identify volunteers for CMAM from their community. Step 6: Conducting Case-Finding and Referral of New Cases with SAM Active case-finding involves identification of children with SAM in the communities and is important to ensure that children with SAM are identified before they develop severe medical complications, which make their condition harder to treat. Identified children are referred to the appropriate care services. It is recommended that all children under 5 are routinely screened for SAM since it is one of the most important contributing causes of childhood mortality. Widespread identification of children with SAM at the community level is achieved through timely screening using MUAC measurement and assessment for the presence of bilateral pitting oedema. Community outreach workers can perform the bilateral pitting oedema check and MUAC measurement after having received training to ensure they can accurately screen. Case-finding and referral is carried out by community outreach workers (e.g., CHWs, volunteers) who are trained to identify children with SAM at all points of contact with the community, according to the developed strategy. The community screening and its training is standardised (see Annex 3. Anthropometric Measurements). Therefore, the quality of the community screening whether performed by community volunteers or extension workers is the same as the screening performed at the health facility by a health care provider. In this way, children who are correctly screened at the community level will also be admitted to the treatment service. Thus, there is no discrepancy between the two systems. The screening procedure is as follows: Bilateral pitting oedema is checked by pressing the thumbs for three seconds on both dorsal sides of the feet. If the indentation remains after removal of the thumb pressure, the child is diagnosed with having bilateral pitting oedema or kwashiorkor, a sign of SAM (see Annex 3. Anthropometric Measurements). Measurement of MUAC for children 6-59 months is made possible through use of simple plastic tapes designed to measure the arm circumference. In the absence of a road to health card or birth certificate, determination of an infants age is based on recall of the caregiver. Infants under 6 months with bilateral pitting oedema and/or visible wasting are not measured but referred to the health facility where they are further investigated. A referral slip is used to refer children identified with SAM to the nearest health facility with CMAM services. (See Annex 23. Referral Slip Community Screening.)  SHAPE \* MERGEFORMAT  Step 7: Conducting Home Visits for High-Risk Cases The role of the community outreach worker is to identify children with acute malnutrition and refer them for treatment. Thus, they know most of the children in their community who are in treatment. They will be asked to follow the children more closely in the case of a problem or concern, if they are at increased risk of death or developing other serious illness. Children in treatment for SAM are monitored at the health facility to ensure sustained improvement in their condition. If the child is not thriving, the health care provider will discuss this with the mother/caregiver and request that the outreach worker pay a home visit to provide support and/or investigate the home environment (see Annex 17. Action Protocol in Outpatient Care) The outreach worker will provide feedback to the health care provider on problems related to the childs home environment. Cases where home visits are critical include (high-risk or problem cases): Child is absent from the weekly session, or is a defaulter (absent for three consecutive visits) Child is not gaining weight or is losing weight on a follow-up visit (non response to treatment) Childs oedema is not reducing (non response to treatment) Child has returned from inpatient care or caregiver has refused inpatient care Child has a deteriorating medical condition Absentees from outpatient care should be followed up with by outreach workers. It is important to gain an understanding of the reason for the absence and to encourage a return to treatment. The absentee should not be reprimanded as this can discourage return. If possible, a home visit record is filled and shared with the health care provider at the outpatient care site (see Annex 24. Home Visit Record Form). A checklist for home visits is made available to guide the outreach worker with the investigation in the home (see Annex 25. Checklist for Home Visits). The health care provider liaises with the community outreach worker by direct contact or through exploiting available communication channels in the community to convey the message to arrange a home visit to high-risk children. Step 8: Linking with Other Community Services, Programmes and Initiatives Children with acute malnutrition are often from very poor families and/or live in a very vulnerable environment exposed to food insecurity, poor mother and child feeding and care practices, and a poor public health environment. It is recommended that families with children with acute malnutrition are targeted by community initiatives that improve their home environment and promote access to an improved quality diet. Through the mapping exercise (see Step 1), community health, nutrition or livelihoods services or initiatives are identified that exist in the area and may be complementary to CMAM. It is recommended that health care providers, health managers and community outreach coordinators discuss ways to link mothers, caregivers or households with children with acute malnutrition to these initiatives. Figure 2. Stages in Community Outreach     3. Outpatient Care for the Management of SAM Without Medical Complications in Children 6-59 Months Outpatient care is aimed at providing treatment for children 6-59 months with severe acute malnutrition (SAM) who have an appetite and are without medical complications in the community. It achieves this objective through timely detection, referral and early treatment before the health condition is severe or before the onset of a complication. Effective community mobilisation, active case finding, referral and follow-up form the cornerstone of successful outpatient care. The treatment protocol of SAM for children 6-59 months in outpatient care is similar to that for inpatient care. If the condition of a child in outpatient care deteriorates, or if a complication develops, then the child is referred to inpatient care for stabilisation, and returns to outpatient care as soon as the medical complication is resolving. Outpatient care services should be carried out on a weekly basis; however, sessions can be conducted every two weeks under certain circumstances: Poor access or long distance to the health facility increases the opportunity cost for the caregivers and may prevent weekly participation Weekly sessions and high case loads overburden health facility schedules or staff at smaller health facilities; in this case, biweekly sessions could allow for splitting the group of children in two and alternating by week or allow a selected group of children only (those who are responding well to treatment) Seasonal factors or events that involve caregivers, such as harvest or planting season, may prevent caregivers from participating weekly Decision on a case by case basis as determined by nutrition or health staff 3.1 Screening of Children for SAM Successful management of SAM in the community requires that an efficient, active case-finding and referral system is established to ensure that children receive appropriate care in a timely manner. The planning phase of the community outreach component for CMAM identifies strategies for comprehensive community screening and referral that will be achieved in a number of ways: Referral by a trained community outreach worker Self referral (i.e., child brought for treatment by caregiver) Ripple effect of caregiver-to-caregiver referral within the community Referral by health or nutrition programmes or initiatives, such as growth monitoring and health extension campaigns, or through any contact with the primary or secondary health care system Children are screened for SAM at the health facility. For some of these children, this could be a second-level screening. It is essential that the strategy for community screening is compatible with the screening upon admission to CMAM services at the health facility. The quality of the community screening should be high so as to avoid referrals being refused by the facility, as this could be damaging for the appreciation and the uptake of the service. If referred children are inaccurately assessed on a regular basis, action should be taken to retrain the outreach worker. 3.2 Admission Criteria for Outpatient Care Usually, the first point of contact with the health care system for a child under 5 with SAM will be the health facility providing outpatient care. The trained health care provider will conduct a medical and nutrition assessment to guide the decision of whether to admit the child 6-59 months to outpatient care or refer the child to inpatient care based on certain admission criteria (see Table 3). The outpatient care site is usually the entry point for admission to CMAM. Criteria for admission are based on anthropometric assessment of severe wasting and clinical presence of bilateral pitting oedema. In addition, clinical signs in children 6-59 months with SAM are essential to assess because they indicate the severity of illness and will determine whether the child is treated in inpatient care or outpatient care. Table 4 provides the case definitions for medical complications of importance in the presence of SAM. Moreover, other clinical signs of wasting may be present without anthropometric confirmation, e.g., skin on the buttocks has a baggy pants look. In exceptional cases, a child 6-59 months with SAM with medical complications but who has appetite and is refusing inpatient care can be admitted to outpatient care for social reasons. And vice versa, a child 6-59 months with SAM eligible for outpatient care can be admitted to inpatient care for social reasons. Table 3. Admission Criteria to CMAM for Children Under 5 Inpatient Care  Outpatient Care  CHILDREN 6-59 MONTHS  FORMCHECKBOX  Bilateral pitting oedema +++  CHILDREN 6-59 MONTHS  FORMCHECKBOX  Bilateral pitting oedema + and ++ OR  FORMCHECKBOX  Any grade of bilateral pitting oedema with severe wasting OR  FORMCHECKBOX  Severe wasting (MUAC < 115 mm or WFH < -3 z-score) AND Appetite test passed No medical complication Child clinically well and alert OR  FORMCHECKBOX  SAM with any of the following medical complications:Anorexia, poor appetite Intractable vomiting Convulsions Lethargy, not alert Unconsciousness Hypoglycaemia High fever Hypothermia Severe dehydration Persistent diarrhoea Lower respiratory tract infection Severe anaemia Eye signs of vitamin A deficiency Skin lesion OR  FORMCHECKBOX  Referred from outpatient care according to action protocol INFANTS < 6 MONTHS  FORMCHECKBOX  Bilateral pitting oedema OR  FORMCHECKBOX  Visible wasting - Includes infants with SAM e" 6 months and < 4 kg  Table 4. Case Definitions of Medical Complications with SAM Medical ComplicationCase DefinitionAnorexia, poor appetite*Child is unable to drink or breastfeed. Child failed RUTF appetite test.Intractable vomiting*Child is vomiting after every oral intakeConvulsions*During a convulsion, the child has uncontrollable movements of limbs and/or face, and/or rolling eyes and/or loss of consciousness. Ask the mother if the child had convulsions during this current illness.Lethargy, not alert*Child is difficult to wake. Ask the mother if the child is drowsy, shows no interest in what is happening around him/her, does not look at the mother or watch her face when talking, or is unusually sleepy.Unconsciousness*Child does not respond to painful stimuli (e.g., injection).HypoglycaemiaThere are often no clinical signs for hypoglycaemia. One sign that does occur in a child with SAM is eye-lid retraction: child sleeps with eyes slightly open.High feverChild has a high body temperature axillary temperature e" 38.5 C or rectal temperature e" 39 C  taking into consideration the ambient temperature.Hypothermia Child has a low body temperature  axillary temperature < 35 C or rectal temperature < 35.5 C  taking into consideration the ambient temperature.Severe dehydrationFor children with SAM, diagnosis of severe dehydration is based on recent history of diarrhoea, vomiting, high fever or sweating, and on recent appearance of clinical signs of dehydration as reported by the caregiver.Persistent diarrhoeaAn episode of diarrhoea which starts acutely but which lasts at least 14 daysLower respiratory tract infection Child has a cough with difficult breathing, fast breathing (if child is 2-12 months: 50 breaths per minute or more; if child is 12 months - 5 years: 40 breaths per minute or more) or chest indrawing.Severe anaemiaChild has palmer pallor or unusual paleness of the skin (compare the colour of the childs palm with the palms of other children); Haemoglobin (Hb) < 40 grams per litre (g/l), or if there is respiratory distress and Hb is between 40 and 60 g.Eye signs of vitamin A deficiencyStages of xerophthalmia are: conjunctival xerosis or dry, opaque and dull conjunctiva with or without Bitots spots (foamy material on conjunctiva); corneal xerosis or dry and dull cornea; keratomalacia or ulceration, necrosis, perforation of cornea, leading to total blindness.Skin lesionChild has broken skin, fissures or flaking of skin.* denotes Integrated Management of Childhood Illness (IMCI) danger signs 3.3 Admission Procedure at the Health Facility Upon arrival at the health facility with CMAM services, the child and caregiver are welcomed and informed about the admission procedure. Critically ill children are triaged and receive priority treatment. Sugar water is made available to prevent hypoglycaemia (see Box 4 and Annex 9. Sugar Water Protocol). First, the childs nutritional status is defined based on standardised measurements and checks (see Annex 3. Anthropometric Measurements). The nutrition assessment involves: Clinical check for the presence of bilateral pitting oedema MUAC anthropometric measurement for children 6-59 months Weight measurement The target weight for discharge at 15 percent weight gain (of admission weight or weight free of oedema) is identified and indicated on the treatment card (see Annex 5. Guidance Table to Identify Target Weight for Discharge) Not compulsory, and only done if equipment and skills are available: Length or height is measured. The WFH category is identified and indicated on the treatment card (see Annex 4. Anthropometry Look-Up Tables). Children who meet the admission criteria for CMAM receive a medical assessment consisting of a medical history and physical examination, including an appetite test (see Box 5). The medical history includes: Diet before current episode of illness Breastfeeding history Food and fluids taken in the past few days Recent sinking of eyes Duration and frequency of vomiting, appearance of vomit Duration and frequency of diarrhoea, appearance of diarrhoeal stools Time when urine was last passed Contact with people with measles or TB Any deaths of siblings Birth weight Motor development milestones reached (e.g., sitting up, standing) Immunisation status Place of origin The physical examination includes: MUAC, weight and length or height Bilateral pitting oedema Appetite test Enlargement or tenderness of the liver, jaundice Abdominal distension, bowel sounds, abdominal splash (a splashing sound in the abdomen) Severe pallor Signs of circulatory collapse: cold hands and feet, weak radial pulse, diminished consciousness Body temperature: hypothermia or fever Thirst Eyes: signs indicative of vitamin A deficiency Ears, mouth, throat: evidence of infection Skin: evidence of lesion, infection or purpura Respiratory rate and type of respiration: signs of pneumonia or heart failure Appearance of stool The outcome of both the medical and nutrition assessment determines if the child will be admitted and receive treatment in outpatient care or is to be referred to inpatient care. This process is called triage. All infants under 6 months with bilateral pitting oedema or visible wasting and children over 5 years with SAM are referred to inpatient care immediately. The choice of the caregiver to enrol the child in inpatient or outpatient care will be considered and options and consequences will be discussed with the caregiver. The caregiver receives advice on the treatment, progress and duration of the illness; the intake of antibiotics and RUTF; and care practices and is asked to return to the health facility for follow-up monitoring sessions or whenever a problem arises until the child has recovered (see Annex 18. Key Messages Upon Admission to Outpatient Care). The caregiver will be linked to the community outreach worker that covers his/her community. The caregiver will also be linked with other services or initiatives as appropriate. Additional points to consider during the admission procedure: Explain to the caregiver the outcome of the assessment and the proposed treatment, and discuss with the caregiver whether the child will be treated in outpatient or inpatient care. The social condition of the caregiver must be taken into consideration. Children who fail the appetite test should always be referred to inpatient care. If the appetite test is inconclusive, the child should always be referred to inpatient care until the appetite has been restored. Note: Children in the community and at all points of contact with the primary health care system are checked for signs of acute malnutrition by the use of the MUAC and presence of oedema. Children with SAM who are referred by a community outreach worker during community screening are reassessed at the health facility to cross check on the accuracy of the referral decision. The referral criteria at community screenings and admission criteria have to be compatible. If the referred child fails to fulfil the admission criteria, he/she should not be admitted, but the caregiver can be linked with other primary health services or initiatives as appropriate (e.g., supplementary feeding, expanded programme of immunisation [EPI]). As such, the outreach workers skills are indirectly verified (e.g., how many were referred that did not fulfil the admission criteria?) and the need for improved supervision or retraining are identified.  SHAPE \* MERGEFORMAT  Box 5. Appetite Test For children meeting the anthropometric criteria for admission for treatment of SAM, the appetite test forms the most important criteria for deciding whether to treat a child with SAM in outpatient care or inpatient care, in addition to the presence or absence of severe medical complications. The pathophysiological responses to nutrient depletion in children with SAM are such that liver and metabolic functions are disturbed and dysfunctional, leading to poor appetite. In addition, children with a significant infection can lose appetite in the acute phase. This puts children with SAM with poor appetite at higher risk of death. The appetite is tested upon admission and is repeated at each follow-up visit to the health facility. Points to consider when conducting an appetite test: Conduct the appetite test in a quiet separate area. Provide an explanation regarding the purpose of the test to the caregiver and describe the procedure. Observe the child eating the RUTF during 30 minutes, and decide if the child passes or fails the test. Advise the caregiver to: Wash hands before giving the RUTF Sit with the child in lap and gently offer the RUTF Encourage the child to eat the RUTF without force-feeding Offer plenty of clean water to drink from a cup when child is eating the RUTF Appetite Test: Pass Appetite Test Fail Appetite Test The child eats at least one third of a packet of RUTF (92 g) or three teaspoons from a pot. The child does NOT eat one third of a packet of RUTF (92 g) or three teaspoons from a pot. Note: If necessary, arrange a quiet corner where the child and caregiver can take their time to get accustomed to eat the RUTF. Usually the child eats the RUTF in 30 minutes. A child who fails the appetite test should be admitted to inpatient care.  3.3.1 Admission Categories New Cases Children 6-59 months with SAM meet the criteria for outpatient care and are directly admitted for treatment in outpatient care. Note: Relapsed cases are considered new cases, as the children were successfully treated before and now have a new episode of acute malnutrition. Children Referred from Inpatient Care (Old Cases) Children with SAM are referred from inpatient care after stabilisation to continue treatment as outpatients. Children with SAM under treatment in another outpatient site could move to the new outpatient care site. Returned Defaulters (Old Cases) Children who defaulted from treatment before recovery return to continue treatment. Figure 3. Admission and Treatment Flow Chart, Children 6-59 Months with SAM  3.3.2 Key Messages for the Individual Counselling of the Caregiver upon Admission The key messages upon admission are brief and simple (see Annex 18. Key Messages Upon Admission to Outpatient Care). Upon the next visits to the health facility, the health and nutrition messages are expanded (see Annex 19. Health and Nutrition Education Messages). The key messages are: RUTF is a food and medicine for very thin and swollen children only. Do not share it. Sick children often dont like to eat. Give small regular meals of RUTF and encourage the child to eat often (if possible, eight meals per day). Your child should have __ packets per day. For young children, continue to breastfeed. Offer breast milk first before every RUTF feed. RUTF is the only food sick and thin/swollen children need to recover during their time in outpatient care. Always give RUTF before other foods, such as porridge local name. Always offer plenty of clean water to drink while eating RUTF. Children will need to drink more water than normal. Use soap for the childs hands and face before feeding. Keep food clean and covered. Sick children get cold quickly. Always keep the child covered and warm. For children with diarrhoea, continue feeding. Give them extra food and water. Return to the health facility whenever the childs condition deteriorates or if the child is not eating sufficiently. Note: Ask the caregiver to repeat back the information to check that the messages have been correctly understood. Upon the next visits to the health facility, the health and nutrition messages are expanded (see Annex 19. Health and Nutrition Education Messages). 3.4 Routine Medication 3.4.1 Children Admitted Directly into Outpatient Care Children admitted directly into outpatient care receive routine medication. Children with SAM do not show the usual signs of infection, such as fever, and infections are hidden. Therefore, routine medication is provided upon admission. The health care provider will decide if additional medication is needed for apparent medical conditions. (See Annex 6. Routine Medicines Protocols, Annex 7. Supplemental Medicines Protocols and Annex 8. Drug Doses.) Antibiotic Treatment with Amoxicillin Give oral antibiotic treatment for a period of five days to be taken at home (give 10 days if needed), based on a dose 50-100 mg/kg bodyweight/day. The first dose should be taken during the admission process under the supervision of the health care provider. An explanation should be given to the caregiver on how to complete the treatment at home. If there is a need for a second-line antibiotic drug, the child will be referred to inpatient care (see Annex 8. Drug Doses). Table 5. First-Line Antibiotic Treatment: Amoxicillin, Three Times a Day for Five Days (50-100 mg/kg Bodyweight/Day) Age (or weight) of the childSyrup 125 mg/5 ml 5 daysSyrup 250 mg/5 ml 5 daysTablets 250 mg 5 days< 12 months (or <10 kg)125 mg or 5 ml 3x a day125 mg or 2.5 ml 3x a day125 mg or tablet 3x a day1- < 10 years (or 10-30 kg)250 mg or 10 ml 3x a day250 mg or 5 ml 3x a day250 mg or 1 tablet 3x a day10 years+ (or >30 kg)Give tabletsGive tablets500 mg or 2 tablets, 3x a day Malaria Treatment Systematically screen all children for malaria in endemic areas on admission regardless of their body temperature, if diagnostic tests are available. If in clinical doubt or symptoms, repeat the malaria test in the weeks following the initial test. If no diagnostic test is available but malaria symptoms are diagnosed, treat the child. Treat malaria according to the national treatment protocol with first-line artemisinin-based combination therapy (ACT) in compliance with Integrated Management of Childhood Illnesses (IMCI) treatment. Note: A child with SAM cannot auto-regulate his/her body temperature well and tends to adopt the temperature of the environment; thus the child will feel hot on a hot day and cool on a cool day. In malaria-endemic areas, children with SAM should be provided with insecticide-treated bednets to prevent malaria. First-Line Antimalarial ACT: Artesunate (AS) and Amodiaquine (AQ) Table 6. Malaria Treatment Based on Artesunate [AS 50 mg Tablet] and Amodiaquine [AQ 153 mg Tablet] Age (or weight)Day 1 InitiallyDay 2Day 3TOTAL Number of Tablets< 4 kgNot recommended<1 year (or 4-8 kg) AS and AQ AS and AQ AS and AQ31-5 years (or 9-15 kg)1 AS and 1 AQ1 AS and 1 AQ1 AS and 1 AQ65-15 years (or 16-35 kg)2 AS and 2 AQ2 AS and 2 AQ2 AS and 2 AQ12Adult (or > 35 kg)4 AS and 4 AQ4 AS and 4 AQ4 AS and 4 AQ24 Second-Line Antimalarials: Coartem or Quinine In the case of severe malaria, the child is referred to inpatient care and treatment with a second-line antimalarial drug is provided (see Annex 8. Drug Doses). Measles Vaccination Give a single vaccine on week four (or upon discharge) if there is no record of a previous vaccination. Infants under 12 months who receive a measles vaccination will need one routine measles vaccination when they have reached 12 months. In the case of a measles epidemic in the area, provide measles vaccination upon admission to outpatient care and repeat the vaccination on week four (or upon discharge). Deworming Treatment Give a single dose of Albendazole or Mebendazole at the second week in treatment, in compliance with the IMCI treatment protocol and/or adapt according to the national protocol. Do not give Albendazole or Mebendazole to children under 1 year. Table 7. Antihelminthic Drug Dosage, Single Dose Albendazole [400 mg Tablet] or Mebendazole [500 mg Tablet] Age (Weight) of the childAlbendazoleMebendazole< 1 yearNONO1-2 years (or < 10 kg)200 mg or Tablet250 mg or Tablete" 2 years (or e"10 kg)400 mg or 1 Tablet500 mg or 1 Tablet Vitamin A Give a single dose on the fourth week or upon discharge: 100,000 international units (IU) for infants 6-11 months and 200,000 IU for children 12 months and older. Cases with bilateral pitting oedema should receive vitamin A when the oedema has resolved or upon discharge. Refer any child with signs of vitamin A deficiency to inpatient care for immediate start of, as the condition of the eyes can deteriorate very rapidly and the risk of blindness is high. Iron and Folic Acid Iron and folic acid are NOT to be given. Small amounts are available in RUTF. Where anaemia is identified according to IMCI protocols, children are referred to inpatient care and receive treatment in compliance with the IMCI treatment protocol. In inpatient care, if the child is on a therapeutic milk diet, folic acid 5 mg on day one and 1 mg per day starting on day two is given, and iron 3 mg/kg bodyweight/day is given after two days on F100 when the child is gaining weight. In inpatient care, if the child is on a RUTF diet, neither folic acid nor iron is supplemented. Iron and folic acid should never be provided together with a malaria treatment. Vaccination Schedule Update Good collaboration is required between the Expanded Programme on Immunization (EPI) and outpatient care for updating the vaccination status of the child. It is important to know the schedule of the child health initiatives and national immunisation campaigns, and if the child participated, to avoid double administration of vitamin A. During regular vaccination sessions or campaigns the team of vaccinators should have one trained person to identify and refer children with acute malnutrition. Note: Children identified with SAM commonly have diarrhoea but should not be referred for oral rehydration therapy (ORT) to receive oral rehydration salt (ORS). Children with SAM and severe dehydration (diagnosis based on recent history of profuse watery diarrhoea and recent change in childs appearance) are referred to inpatient care and will receive treatment for rehydration based on a rehydration solution for malnutrition (ReSoMal), which contains less sodium and more potassium then ORS. ReSoMal for instance is always provided in controlled amounts and never given freely for use to the child and/or caregiver. ORS provided to a child with SAM could enhance bilateral pitting oedema and invoke sodium overload and heart failure. 3.4.2 Children Referred from Inpatient Care Children who have been referred from inpatient care or another outpatient care site should not be given routine medicines for a second time as they have already been administered to them. The childs records and documentation should be checked for details of medications already given and, where applicable, the remaining schedule of medications and supplements should be continued according to protocol. 3.5 Dietary Treatment Children receive RUTF based on a dose of +- 200 kcal/kg bodyweight/day given as a take-home ration. A weekly supply of RUTF is provided depending on the childs bodyweight (see Table 8). The dietary treatment is managed at home, with the children attending outpatient care sessions on a weekly basis for monitoring health and nutritional status and replenishing stocks of RUTF. 3.5.1 Quantities of RUTF to Provide Provide 200 kcal per kg bodyweight per day of RUTF. Use the RUTF look-up tables for the amounts of RUTF to give on each weekly visit, based on the childs weight. One sachet RUTF of 92 g provides 500 kcal. Explain the daily amount the child will need to consume to the caregiver. Give the required RUTF ration to the caregiver. Table 8. Look-Up Table for Amounts of RUTF to Give to a Child per Day or Week Based on a Dose of 200 kcal/kg Bodyweight/Day Using 92 g Packets Containing 500 kcal Childs Weight (kg)Packets per DayPackets per Week4.0* 4.92145.0 6.92.5187.0 8.43218.5 9.43.5259.5 10.442810.5 11.94.532( 12535* Infants < 4 kg are referred to inpatient care 3.5.2 Feeding Procedure The caregiver is advised to feed the child with small amounts of RUTF, encourage the child to finish the allocated daily ration before giving any other foods (except for breast milk) and encourage the child to eat as often as possible (every three-to-four hours). The RUTF ration is a full food ration for the child; the child should not eat anything else except breast milk during the first week. The breastfed child should be offered breast milk on demand and before being fed RUTF. Safe drinking water should be given after feeding the child RUTF to keep the child hydrated. Caregivers should be advised not to mix RUTF with liquids as this may foster bacteria growth. Key messages are provided upon admission and are also repeated upon every visit and follow the sequence of: wash hands before feeding, breastfeed first, offer small amounts of RUTF spread over the day and offer safe drinking water during the feeding (see Annex 18. Key Messages Upon Admission to Outpatient Care). Caregivers could be asked to return empty RUTF packets (or pots) at each follow-up visit. 3.6 Individual Monitoring During Follow-up Visits Individual monitoring of the childs progress should be carried out by the health care provider upon weekly (or as circumstances dictate, biweekly) return visits to the health facility or outreach point. The following parameters are monitored and recorded on the treatment card during the follow-up visit: Anthropometry MUAC Weight Physical examination Degree of bilateral pitting oedema Weight gain: The weight is marked and compared to the weight of the previous weeks and with the target weight for discharge (see Annex 5. Guidance Table to Identify Target Weight for Discharge) Children who lose weight or have no weight gain or have their weight fluctuating receive special attention during the medical examination (see Annex 17. Action Protocol in Outpatient Care) and according to the evaluation a decision is taken to continue treatment in outpatient care, or refer (see 3.8 below). Body temperature Standard clinical signs: stool, vomiting, dehydration, cough, respiration, liver size, eyes, ears, skin condition and peri-anal lesions are assessed Appetite test Any illness suffered by the child since the last visit Any action taken or medication given in response to a health condition At each follow-up visit, the caregiver should be informed of the childs progress and individual and/or group counselling is provided on standardised health and education messages. After the initial weeks of treatment, special attention should be paid to the gradual introduction of quality complementary foods to prepare the child for gradual weaning off the RUTF (see Annex 19. Health and Nutrition Education Messages). Follow-up action is based on the action protocol (see Annex 17. Action Protocol in Outpatient Care). The action protocol describes when to decide for home visit, referral to inpatient care or referral for medical investigation. Children who were absent for one or more visits are tracked in the community (including those who were discharged because they became defaulters after three absent visits). 3.7 Home Visits The outreach worker covering the geographical area of a childs place of origin should be assigned to make home visits for children requiring special attention during the treatment process. Home visits should include assessing the nutrition and health condition of the child, compliance with feeding practices for RUTF and home caring practices. The outreach worker provides individual counselling to the caregiver and feeds back the information to the health care provider. Home visits for children with SAM are essential in the following high-risk or problem cases (see Annex 17. Action Protocol in Outpatient Care): Child is absent from the weekly session, or is a defaulter (absent for three consecutive visits) Child is not gaining weight or is losing weight on a follow-up visit (non response to treatment) Childs oedema is not reducing (non response to treatment) Child has returned from inpatient care or caregiver has refused inpatient care Child has a deteriorating medical condition A system to monitor home visits should be kept at the outpatient care site (see Annex 24. Home Visit Record Form and Annex 25. Checklist for Home Visits). 3.8 Criteria to Refer the Child from Outpatient Care to Inpatient Care or for Medical Investigation Children with SAM in outpatient care who develop medical complications or who are not responding well to treatment are referred to inpatient care, according to the action protocol (see Annex 17. Action Protocol in Outpatient Care). The following medical complications and deterioration of nutritional status require referral to inpatient care or for medical investigation: Poor appetite: failed appetite test Other IMCI danger signs: intractable vomiting, convulsions, lethargy/not alert, unconsciousness Deteriorating general condition Increase in or newly developed bilateral pitting oedema Less than admission weight on third week Weight loss for two consecutive visits Static weight (no weight gain) for three consecutive visits Hypoglycaemia, dehydration, high fever, hypothermia, persistent diarrhoea, high respiratory rate, anaemia, eye signs of vitamin A deficiency, skin lesion, infection in need of second-line or intramuscular (IM) antibiotic treatment, no response to treatment In addition, the absence or death of the caregiver can lead the new caregiver to request inpatient care. Also, referral to inpatient care must be granted upon request from the caregiver at any time. If a child is referred to inpatient care, it is essential that a referral form or road to health card is used to provide basic health and nutrition information, including a description of the treatment, reasons for referral, and vaccination status (see Annex 30. Referral Form for Inpatient Care/Outpatient Care). If a referral system already exists in the health facility, then this should be used. What is of importance is that the nutrition and medical information is recorded and shared with the health care provider at the next level. 3.9 Failure to Respond to Treatment in Outpatient Care Some children in outpatient care will fail to respond to treatment or their condition can deteriorate despite the treatment. A child in outpatient care who meets any of the criteria as described in Table 9 are diagnosed as failing to respond to treatment. Based on the action protocol (see Annex 17. Action Protocol in Outpatient Care), the child receives a home visit or is referred to a health facility with expertise in inpatient care for SAM with medical complications for medical investigation and specialised treatment. Table 9. Criteria for Defining Failure to Respond to Treatment in Outpatient Care Primary failure* to respond to treatmentTime since admissionFailure to gain weight (non-oedematous child)21 daysOedema still present21 daysFailure to start to lose oedema14 daysOedema still present21 daysSecondary failure* to respond to treatmentTime or durationFailure of appetite testAt any visitWeight loss For 14 daysStatic weight For 21 daysBelow admission weight After 21 days in treatment* Primary failure to respond means when the criteria has been noticed since admission. Secondary failure to respond means when the child has shown improvement and then later deteriorates as described by the criteria. Actions to be considered: Community health worker or volunteer conducts home visit to check whether a child should be referred back to the health facility between follow-up visits. Health care provider discusses with caregiver aspects of the home environment that may affect the childs progress. If these actions are not immediately successful, an external evaluation could be requested to verify the organisation of the services and the compliance to treatment protocols. Common causes of failure to respond to treatment (see Box 6) should be systematically examined to determine and rectify the problem. Box 6. Examples of Frequent Causes of Failure to Respond to Treatment in Outpatient Care Problems Related to the Quality of the Treatment Inappropriate evaluation of childs health condition or missed medical complication Inappropriate evaluation of appetite test Non-adherence to RUTF protocol Non-adherence to routine medication protocol Inadequate guidance for home care provided Problems Related to Home Environment Inappropriate frequency of visits and reception of RUTF Inadequate intake or sharing of RUTF and/or medicines 3.10 Discharge Criteria The child is fully recovered if the following discharge criteria are met: 15 percent weight gain maintained for two consecutive visits (of admission weight or weight free of oedema) (see Annex 5. Guidance Table to Identify Target Weight for Discharge) No bilateral pitting oedema for two consecutive visits Clinically well and alert Other children that are discharged but did not meet the discharged cured criteria (thus did not recover) are children who: Died while in treatment Defaulted or were absent for the third consecutive week or outpatient care session Did not recover or did not meet the discharge criteria after four months in treatment; during the treatment, these children would have shown signs of non-response to treatment and been referred to inpatient care or for medical investigation based on the action protocol It is recommended that the following elements are considered at discharge: Health and nutrition education scheme is completed Appropriate weaning of RUTF is reached Immunisation schedule is updated Adequate arrangements for linking the caregiver and child with appropriate community initiatives and services (e.g., supplementary feeding) and for follow-up are made 3.11 Discharge Procedures The following elements should be addressed before the child is discharged: Provide feedback to the caregiver on the final outcome of treatment Counsel caregiver on good feeding and care practices, including on providing and preparing appropriate complementary food Ensure caregiver understands importance of follow-up care to prevent relapse (e.g., enrolment in supplementary feeding and other child health and nutrition programmes) Note discharge outcome in register and treatment card Advise the caregiver to immediately return if the child refuses to eat or has any of the following signs: High fever Frequent watery stools or stools with blood, diarrhoea lasting more than four days Difficult or fast breathing Vomiting Not alert, very weak, unconscious, convulsions Bilateral pitting oedema Give final ration of RUTF (one week supply) Ideally, children discharged from outpatient care should be referred to supplementary feeding where available for a minimum of two months, regardless of their nutritional status. 3.12 Infant and Young Child Feeding Support Annex 19. Health and Nutrition Education Messages summarizes health and nutrition education messages that can be used for individual and group counselling for improving and supporting IYCF practices. It provides a list of key behaviours to promote, summarizes the importance of breastfeeding for the infant and young child, and recommends IYCF practices on breastfeeding and complementary feeding. It also provides an example of a country-adapted tool for recommended foods for infants and young children. 4. Inpatient Care for the Management of SAM with Medical Complications for Children 6-59 Months Inpatient care for the management of SAM with medical complications can be provided in a special section of the paediatric ward or health facility with 24-hour care. Staff at these health facilities should have been specifically trained in the management of SAM with medical complications. Children 6-59 months with SAM with poor appetite or with medical complications and children being referred from outpatient care because their medical condition is deteriorating (see Annex 17. Action Protocol in Outpatient Care) are admitted to inpatient care. Children with SAM with appetite or without medical complications may exceptionally be admitted to inpatient care for social reasons (e.g., no caregiver, security problem), to be decided by the supervisor of the health facility. Children 6-59 months admitted into inpatient care for stabilisation will be referred to outpatient care as soon as the medical complication is resolving, the appetite has returned and/or the oedema is reducing. Exceptionally, children will complete the full treatment in inpatient care, because, e.g., child cannot eat RUTF, RUTF is not available, social reason. All infants under 6 months with SAM are admitted in inpatient care until full recovery (see Section 5). Older children, adolescents and adults with SAM will be admitted in inpatient care until full recovery (see Section 6). 4.1 Admission Criteria Box 7. Admission Criteria for Inpatient Care Children 6-59 months Bilateral pitting oedema +++ Any grade of bilateral pitting oedema with severe wasting SAM (bilateral pitting oedema + or ++ or severe wasting) with any of the following medical complications: Anorexia, poor appetite Intractable vomiting Convulsions Lethargy, not alert Unconsciousness Hypoglycaemia High fever Hypothermia Severe dehydration Persistent diarrhoea Lower respiratory tract infection Severe anaemia Eye signs of vitamin A deficiency Skin lesion Referred from outpatient care according to action protocol Other: e.g., infants e" 6 months and < 4 kg with SAM follow the SAM treatment protocol as infants < 6 months  4.2 Admission Procedure Upon arrival at the health facility, the child and caregiver are welcomed and informed about the admission procedure. The childs weight, height or length, and MUAC is measured and recorded. Critically ill children are triaged and receive priority treatment. Sugar water is made available to prevent hypoglycaemia (see Box 4 and Annex 9. Sugar Water Protocol). Children, upon admission, should directly be assigned to the specific ward for inpatient care. They are not treated or kept in an emergency ward unless the clinical staff in the emergency ward has specific training in the management of SAM with medical complications. Critical care of children with SAM differs from the standard protocols and trained medical staff need to be involved to provide quality care for SAM to reduce the risk of death. The childs medical condition is assessed and life-saving treatment is started as soon as possible, followed by routine WHO treatment protocols for SAM. The WHO 10-step treatment summarises the different life saving steps that need to be considered in the treatment of SAM (see Figure 4). The medical and nutrition assessment information is recorded on the inpatient care treatment card (see Annex 27. Inpatient Care Treatment Card): child information, medical history and the results of the physical examination. Admission registration is completed using the existing registration system. The caregiver should receive counselling on the medical and dietary treatment the child will receive, and on breastfeeding and good hygiene practices. The caregiver should be given soap for handwashing and general hygiene, and food during his/her stay in inpatient care. Ideally, children and their caregivers in the stabilisation phase should be physically separated from those children in the transition and rehabilitation phases, and from children with other diseases. A child 6-59 months in inpatient care who is alert should undergo the appetite test with RUTF (see Box 5). If he/she passes the appetite test but needs admission to inpatient care for medical complications, he/she should take RUTF. A child who fails the appetite test will be put on the milk diet and tested again as soon as the appetite has returned. As soon as the appetite returns, the child graduates to the transition phase and is offered RUTF. The transition from a milk diet to RUTF is gradual, but happens for most children within one day. RUTF is always offered first and complemented with F100 in case of need. A child 6-59 months with SAM without medical complications and appetite will be admitted to inpatient care only if there is an exceptional social or medical reason. This is decided by the supervisor of the health facility in discussion with the caregiver. 4.3 Stabilisation Phase Medical treatment and nutritional rehabilitation of children with SAM and medical complications in inpatient care follow the adapted WHO SAM treatment protocol. As soon as the medical condition is stabilised, the oedema is reducing and/or the medical complication is resolving, the child is referred to outpatient care to continue the nutritional rehabilitation. It is expected that the child is in stabilisation for one to seven days. The general principles of the WHO SAM treatment protocol are: Treat and prevent hypoglycaemia Treat and prevent hypothermia Treat and prevent dehydration Correct electrolyte imbalance Treat and prevent infection Provide micronutrient supplementation Start cautious feeding Achieve transition to catch-up diet Provide sensory stimulation and emotional support Prepare for follow-up after stabilisation and transition Also consider: Treat incipient or developed septic shock, if present Identify and treat any other problems, including vitamin deficiency, severe anaemia and heart failure Figure 4. Overview Treatment of Children with SAM: WHO 10-Step (WHO 1999) Stabilisation PhaseRehabilitation PhaseDays 1 2Days 3 7Weeks 2 61. Hypoglycaemia2. Hypothermia3. Dehydration4. Electrolytes5. Infection6. Micronutrients7. Cautious feeding8. Catch-up growth9. Sensory stimulation10. Prepare for follow-up 4.3.1 Medical Treatment Routine medicines and supplements should follow the schedule as described in outpatient care, (see Section 3.4 Routine Medication). (See also Annex 6. Routine Medicines Protocols, Annex 7. Supplemental Medicines Protocols and Annex 8. Drug Doses.) Also, because children with SAM in inpatient care have a severe form of illness with medical complications, they will need high-level care by very skilled clinicians. The Appendix provides detailed guidance on the management of medical complications in the presence of SAM. Note: The use of intravenous (IV) lines is strictly avoided except in case of shock or circulatory collapse. Special care with intramuscular (IM) injections is taken as children with SAM have reduced muscle mass and the risk of nerve damage is high. 4.3.2 Dietary Treatment Quantities of F75 in the Stabilisation Phase Give 130 ml of F75 (100 kcal) per kg bodyweight per day Give six or eight feeds per day (every three or four hours) Use the look-up tables for the volume of F75 to give to individual child per feed according to the childs bodyweight (see Tables 10 and 11) Notes: Breastfed children should be offered breast milk on demand before being fed F75. Where night feeds are problematic, give five-to-six feeds during the daytime. Hypoglycaemia becomes a risk if the daytime intake is low. The larger volume of F75 that is required with a reduced number of feeds can on rare occasions provoke osmotic diarrhoea. That is why ideally eight or more feeds should be given daily. Feed Preparation For a large number of children: Add one packet of F75 to 2 litres (L) of water. The water needs to be boiled and cooled prior to mixing. For few children: Smaller volumes can be prepared by measuring small amounts of F75 using the red scoop. Add 20 millilitres (ml) boiled and cooled water per one red scoop of F75 powder. If pre-packaged F75 is not available, use one of the recipes to prepare F75 using locally available ingredients and (imported) combined mineral and vitamin mix (CMV) (see Annex 14. Alternative Recipes for F75, F100 and ReSoMal Using CMV). Feeding Procedure Feed by cup and saucer. Only feed with a nasogastric tube (NGT) when the child is unable to take sufficient F75 by mouth. A sufficient amount is defined as intake of 80 percent of the milk. The use of a NGT should not exceed three days and should only be used in the stabilisation phase. Box 8. Summary of Reasons for Using a NASOGASTRIC TUBE (NGT) to Feed the Child During Stabilisation A NGT should be used if the child: Takes less than 80 percent of the prescribed diet per 24-hours during stabilisation Has pneumonia (rapid respiration rate) and has difficulties swallowing Has painful lesions of the mouth Has cleft palate or other physical deformity Shows disturbed level of consciousness Feeding Technique Aspiration pneumonia is very common in severely malnourished children due to muscle weakness and slow swallowing. Therefore, applying the correct feeding technique is important to ensure the child has an adequate milk intake. The child should be on the caregivers lap against her chest, with one arm behind the caregivers back. The caregivers arm encircles the child and holds the cup and saucer under the childs chin. The child should be sitting straight (vertical). The F75 is given by cup and any dribbles that fall into the saucer are returned to the cup. The child should never be force fed, have his/her nose pinched, or lie back and have the milk poured into the mouth. Meal times should be sociable. The caregivers should sit together in a semi-circle around an assistant who talks to the caregivers, encourages them, corrects any faulty feeding technique and observes how the child takes the milk. The meals for the caregivers should be organised by the health facility. The caregivers meals should never be taken beside the child. Sharing of the meal with the child can be dangerous given their delicate pathophysiology. If the caregivers meal has added salt or condiment, it can be sufficient to provoke heart failure in children with SAM. Tables 10 and 11 provide volumes of F75 to give to children with severe wasting and severe bilateral pitting oedema in the stabilisation phase. See also Annex 12. Therapeutic Feeds Look-Up Tables, which provides F75 look-up tables for daily use in the ward. Table 10. Stabilisation Phase Volume of F75 for Persons with Severe Wasting Weight (kg)F75 (ml per feed if 12 feeds per day)F75 (ml per feed if 8 feeds per day)F75 (ml per feed if 6 feeds per day)F75 (ml per feed if 5 feeds per day)2.0 2.1204050652.2 2.4254560702.5 2.7305065752.8 2.9305570803.0 3.4356075853.5 3.9406580954.0 4.44570851104.5 4.95080951205.0 5.455901101305.5 5.9601001201506.0 6.9701101401757.0 7.9801251602008.0 8.9901401802259.0 9.910015519025010 10.911017020027511 11.911519023027512 12.912520525030013 13.913523027535014 14.914525029037515 19.915026030040020 24.916029032045025 29.917530035045030 39.918532037050040 60200350400500 Table 11. Stabilisation Phase Volume of F75 for Persons with Severe Bilateral Pitting Oedema (+++) Weight (kg)F75 (ml per feed if 12 feeds per day)F75 (ml per feed if 8 feeds per day)F75 (ml per feed if 6 feeds per day)F75 (ml per feed if 5 feeds per day)3.0 3.430 35 50 6060 7570 853.5 3.930 4050 6565 8075 954.0 4.435 4055 7070 8590 1104.5 4.935 4565 8070 9595 1205.0 5.445 5570 9090 110105 1305.5 5.950 6080 10095 120120 1506 6.955 7090 110110 140140 1757 7.965 80100 125130 160160 2008 8.970 90110 140145 180180 2259 9.975 95125 155150 190200 25010 10.980 100135 170160 200220 27511 11.995 115150 190185 230220 27512 12.9100 125165 205200 250240 30013 13.9110 135185 230220 275280 35014 14.9115 145200 250230 290300 37515 19.9120 150210 260240 300320 40020 24.9125 170230 290255 320360 45025 29.9140 175240 300280 350360 45030 39.9150 185255 320295 370400 50040 60160 200280 350320 400400 500 4.3.3 Individual Monitoring Individual monitoring of children with SAM in the stabilisation phase should be done continuously. Based on improvement in the childs condition, a decision can be made on progression to the transition phase of the treatment. The following parameters should be monitored daily: Degree of bilateral pitting oedema (0 to +++) is assessed Weight is measured at the same time (before or after feeds), entered and plotted on the individual treatment card Body temperature is measured (twice per day) Standard clinical signs: stool, vomiting, dehydration, cough, respiration, liver size, eyes, ears, skin condition, peri-anal lesions MUAC is taken upon admission and thereafter on each subsequent seventh day Length or height is taken upon admission and after 21 days A record is taken (on the intake part of the treatment card) if the child is absent, vomits or refuses a feed, and whether the child is fed by NGT or is given an IV infusion or transfusion; there are appropriate places for these to be recorded each day Target weight for discharge at 15 percent weight gain (of admission weight or weight free of oedema) is recorded (see Annex 5. Guidance Table to Identify Target Weight for Discharge) 4.3.4 Progression from the Stabilisation to the Transition Phase The criteria to progress from the stabilisation phase to the transition phase are: Return of appetite, and Resolving medical complication, or Reduction of bilateral pitting oedema (checked by appropriate and proportionate weight loss as the oedema starts to subside) Children with severe bilateral pitting oedema (+++) should remain in the stabilisation phase on a F75 diet at least until their oedema has reduced to moderate (++) oedema; these children are particularly vulnerable and at high risk of death. 4.4 Transition Phase When children with SAM complete the stabilisation phase, they start treatment in the transition phase. In the transition phase, medical treatment is continued and there are dietary treatment changes for children 6-59 months: RUTF is progressively introduced and F100 therapeutic milk is used to complement the RUTF feed if the child did not successfully complete the RUTF amount per feed. The quantities of the milk diet provided remain the same as in the stabilisation phase, but the calorie intake changes. The duration of treatment in the transition phase is two-to-three days on average. Children 6-59 months are gradually prepared for referral to outpatient care. As soon as the child passes the appetite test and eats 80 percent of his/her daily RUTF ration, the child will be referred to outpatient care to continue treatment. Older children, adolescents and adults remain on the F100 therapeutic milk diet. 4.4.1 Medical Treatment Routine medicines and supplements should follow the schedule as described in outpatient care. The child can be referred to outpatient care and continue the drug regimen at home if the medical complication is resolving. If a child has to complete his/her antibiotic schedule while in outpatient care, then this should be noted on the childs referral card (see Annex 30. Referral Form for Inpatient Care/Outpatient Care). The information can also be provided on outpatient care treatment cards if they are made available at inpatient care sites or on the road to health card. 4.4.2 Dietary Treatment Because of the return of appetite during the transition phase, the RUTF appetite test is done (see Box 5. Appetite Test). RUTF is offered at every feed and complemented by F100 if needed. Few children might initially refuse the RUTF but should be encouraged to eat RUTF at every meal. If the child takes RUTF voluntarily, stop providing F100. If both F100 and RUTF are being given, they can be substituted on the basis that about 100 ml of F100 equals 20 g of RUTF. The diet should provide an average increase in energy intake of about one third daily over the amount given during the stabilisation phase (e.g.,150 kcal/kg bodyweight/day). Average expected daily weight gain is 5 g/kg bodyweight. Excess weight gain is not a good sign in the transition phase. For children over 6 months but weighing less than 4 kg, only F100-Diluted should be given. Full-strength F100 should not be used. These children are treated as infants under 6 months (see Section 5). Number of Feeds Eight feeds per day should be provided in 24-hour care if sufficient staff is present to prepare and distribute the feeds at night. Five-to-six feeds per day should be provided if there are no night feeds possible, ensuring that the feeds are completed during the day. Breastfed children should be offered breast milk on demand before being fed RUTF or F100. Quantities of RUTF Use the RUTF look-up table and provide quantities of RUTF based on the 150 kcal/kg bodyweight/day (Table 12). A full days amount of RUTF is given to the caregiver, and the amount taken should be checked five times during the day. Children that are not taking sufficient RUTF as inpatients are given F100 to make up any deficit in intake. When the child has passed the appetite test and is taking 80 percent of the daily prescribed amount of RUTF, the child is ready for referral to outpatient care to continue the treatment at home. Tables 12 and 13 provide volumes of RUTF and F100 to give to children in the transition phase. See Annex 12. Therapeutic Feeds Look-Up Tables, which provides F100 and RUTF look-up tables for daily use in the ward. Table 12. Transition Phase Look-Up Table for Amounts of RUTF to Give to a Child per Day Based on a Dose of 150 kcal/kg Bodyweight/Day Using 92 g Packets Containing 500 kcal Childs Weight (kg)Packets per Day3.5 3.91.24.0 4.91.55.0 6.92.17.0 8.42.58.5 9.42.89.5 10.43.110.5 11.93.6( 124Quantities of F100 for Children Who do not Take RUTF The volume of feeds remains the same as in the stabilisation phase. Give 130 ml of F100 or 150 kcal/kg bodyweight/day. Use the transition phase look-up table for the volume of F100 to give per feed according to the childs bodyweight (Table 13). Table 13. Transition Phase Look-Up Table for Volume of F100 per Feed if No RUTF is Taken, Based on 150 kcal/kg Bodyweight/Day Weight (kg)F100 (ml per feed if 8 feeds per day)F100 (ml per feed if 6 feeds per day)F100 (ml per feed if 5 feeds per day)3.0 - 3.46075853.5 3.96580954.0 4.470851104.5 4.980951205.0 5.4901101305.5 5.91001201506.0 6.91101401757.0 7.91251602008.0 8.91401802259.0 9.915519025010 10.917020027511 11.919023027512 - 12.920525030013 - 13.923027535014 - 14.925029037515 - 19.926030040020 - 24.929032045025 - 29.930035045030 - 39.932037050040 - 60350400500 Feed Preparation of F100 For a large number of children: Add one packet of F100 to 2 litres (L) of water (the water needs to be boiled and cooled prior to mixing). For few children: Smaller volumes can be prepared by measuring small amounts of F100 using the red scoop (add 18 millilitres (ml) water per one red scoop of F100 powder). If pre-packaged F100 is not available, use one of the recipes given (see Annex 14. Alternative Recipes for F75, F100 and ReSoMal Using CMV) to prepare F100 using locally-available ingredients and CMV. Feeding Procedure RUTF Provide the RUTF to the caregiver to feed the child. The caregiver should be encouraged to provide RUTF feeds at the same time as feeds were provided during the stabilisation phase (five-to-eight feeds per day). Breastfed children should be offered breast milk on demand before being fed RUTF. Children should be offered as much water to drink as they will take during and after they have taken some of the RUTF. Some children initially refuse the RUTF. If this is the case they should be given the F100 diet for one or two days and then be reintroduced to RUTF when their appetite is fully established. F100 Feeding and timing of F100 feeds in the transition phase is the same as in the stabilisation phase. Breastfed children should be offered breast milk on demand before being fed F100. Never force-feed the child. Feeding Technique RUTF should be given to the caregiver to feed the child. Children should be offered as much clean water to drink as they demand during and after RUTF intake. The feeding technique for F100 is the same as for F75 in the stabilisation phase. 4.3.3 Individual Monitoring Individual monitoring of a severely malnourished child in the transition phase is done daily. Average expected daily weight gain is 5 g/kg bodyweight. Excess weight gain is not a good sign in the transition phase and needs further investigation. Patients with bilateral pitting oedema (kwashiorkor) should remain in the transition phase until there is a definite and steady reduction in oedema to the + level. The following parameters should be monitored daily and entered on the individual treatment card: Weight Degree of bilateral pitting oedema (0 to +++) Body temperature Standard clinical signs: stool, vomiting, dehydration, cough, respiration, liver size, eyes, ears, skin condition and peri-anal lesions are assessed MUAC is taken each week Length or height is taken every three weeks Other records: e.g., absent, vomits or refuses a feed 4.4.4 Progression from the Transition Phase to Outpatient Care Based on improvements in the childs condition, a decision should be made on progression to the next phase: For children 6-59 months: referral to outpatient care to continue treatment until full recovery For older age groups: transition to rehabilitation phase and remain in inpatient care until full recovery Recovering children 6-59 months should progress to outpatient care as soon as they are eating RUTF well. Very few children who cannot take RUTF (or for other reasons) remain in inpatient care. Older age groups will remain in inpatient care on a therapeutic milk diet until full recovery. Criteria to Progress to Outpatient Care for Children 6-59 Months A good appetite: if the child passes the appetite test and takes 80 percent of the daily ration of RUTF Bilateral pitting oedema reducing to moderate (+ +) or mild (+) Resolving medical complication Clinically well and alert Criteria to Progress to the Rehabilitation Phase in Inpatient Care The following criteria for progression from the transition phase to the rehabilitation phase in inpatient care are for the few exceptions of those who do not progress to outpatient care (i.e., children who will not be able to return to their community, children who cannot eat the RUTF): A good appetite: taking at least 90 percent of the F100 prescribed for the transition phase Bilateral pitting oedema reducing to moderate (+ +) or mild (+) Resolving medical complication Clinically well and alert Criteria to Move Back from the Transition Phase to the Stabilisation Phase The child should be moved back to the stabilisation phase if there is: Weight gain of more than 10 g/kg bodyweight/day in association with an increase in respiratory rate (indicative of excess fluid retention) Increasing or developing bilateral pitting oedema Rapid increase in liver size Any signs of fluid overload Tense abdominal distension Significant refeeding diarrhoea so that there is weight loss Note: It is common for the children to get some change in stool frequency when they change diet. This does not need to be treated unless the children lose weight. Several loose stools without weight loss is not a criterion to move back to the stabilisation phase. A complication that necessitates an IV infusion A need for feeding by NGT 4.5 Rehabilitation Phase Few children 6-59 months progressing from the transition phase will require remaining in inpatient care and will move to the rehabilitation phase. This phase is associated with full recovery and rapid catch-up of weight. Children progressing to the rehabilitation phase and who are on an RUTF diet can be referred to the outpatient department (OPD) of the health facility and monitored weekly or bi-weekly if there is no outpatient care site close to his/her community to return to. They should not occupy a bed and be exposed to cross-infections or nosocomial infections. Accommodations for the child and caregiver should be organised outside of the ward in case this is needed. Older children, adolescents and adults remain on the F100 therapeutic milk diet until full recovery. 4.5.1 Medical Treatment The medical part of the treatment for SAM is likely to be completed at this stage. There should be no serious medical complications and the child should have a good appetite. The child is expected to be taking large and/or free amounts of their diet and gaining weight rapidly. Routine medicines that are added in this phase are (see Section 3.4 and Annex 6. Routine Medicines Protocols): Deworming medicine as a single dose Vitamin A supplementation and measles vaccination on week four (or upon discharge) If the child is on F100: Iron sulphate is added to F100 (one crushed tablet 200 mg of iron sulphate is added to 2-2.4 litres (L) of F100), and malaria symptoms are closely monitored and treated If the child is on RUTF: no additional iron is given as it already contains the necessary iron 4.5.2 Dietary Treatment This is the phase when the childs body function is restoring and the child will recuperate weight. The diet based on 200 kcal/bodyweight/day will be RUTF. For those that cannot take sufficient RUTF, F100 is given to make up any deficit of RUTF intake, or F100 is given exclusively for special cases. The mother/caregiver should be encouraged and informed on appropriate care and feeding practices and on how to prevent malnutrition in the child (e.g., separate feeds, good hygiene, return to the health facility if the childs condition deteriorates). (See also Annex 19. Health and Nutrition Education Messages.) If both F100 and RUTF are being given, they can be substituted on the basis that about 100 ml of F100 equals 20 g of RUTF. Number of Feeds Offer RUTF. Those that are not taking sufficient RUTF as inpatients are given F100 to make up any deficit in intake. If both F100 and RUTF are being given, they can be substituted on the basis that about 100 ml of F100 = 20 g of RUTF. Provide RUTF and/or F100 according to childs bodyweight. Give five or six feeds of RUTF and/or F100 per day. Breastfed children should be offered breast milk on demand before being fed RUTF and/or F100. Porridge can be added once a day as an extra feed to prepare the child for weaning off the therapeutic food. Note: Children weighing less than 4 kg must be given F100-Diluted. They should never be given full-strength F100. (See regimen in Section 5.) Quantities of Feeds Quantities of RUTF Use Table 14 to calculate the amount of RUTF to provide. RUTF is provided on the basis 200 kcal/kg bodyweight/day, just as in outpatient care. Quantities of F100 for Children Not Taking RUTF Give 200 ml of F100 which provides 200 kcal/kg bodyweight/day. Use the look-up tables (Table 15) for the volume of F100 in the inpatient rehabilitation phase and give per feed according to childs bodyweight. Tables 14 and 15 provide volumes of RUTF and F100 to give to children in the rehabilitation phase. See also Annex 12. Therapeutic Feeds Look-Up Tables, which provides F100 and RUTF look-up tables for daily use in the ward. Feed Preparation for F100 For large number of children: Add one packet of F100 to 2 litres (L) of water (the water needs to be boiled and cooled prior to mixing). For few children: Smaller volumes can be prepared by measuring small amounts of F100 using the red scoop (add 18 millilitres (ml) water per one red scoop of F100 powder). Feeding Procedure RUTF Provide the RUTF to the caregiver to feed the child. Breastfed children should be offered breast milk on demand before being fed RUTF. Children should be offered as much water to drink as they will take during and after they have taken some of the RUTF. F100 Feed by cup and saucer. Breastfed children should be offered breast milk on demand before being fed F100. After the feed, always offer an additional quantity to the child if he/she takes all the feed quickly and easily. The child should be able to take as much F100 as they want. Gradually replace one feed a day with a porridge. Table 14. Rehabilitation Phase Look-Up Table for Amounts of RUTF to Give to a Child per Day Based on a Dose of +- 200 kcal/kg Bodyweight/Day Using 92 g Packets Containing 500 kcal Childs Weight (kg)Packets per Day3.5 3.91.54.0 4.925.0 6.92.57.0 8.438.5 9.43.59.5 10.4410.5 11.94.5( 125 Table 15. Rehabilitation Phase Look-Up Table for Volume of F100 per Feed if no RUTF is Taken Based on +- 200 kcal/kg Bodyweight/Day Childs Weight (kg)F100 (ml per feed if 6 feeds per day)F100 (ml per feed if 5 feeds per day)3.0 3.41101303.5 3.91201504.0 4.91501805.0 5.91802006.0 6.92102507.0 7.92403008.0 8.92703309.0 9.930036010.0 11.935042012.0 14.945052015.0 19.955065020.0 24.965078025.0 29.975090030.0 39.98501,00040 601,0001,200 4.5.3 Individual Monitoring Individual monitoring of the recovering child in the inpatient care rehabilitation phase is done daily. The following parameters should be monitored daily and recorded on the treatment card: Degree of bilateral pitting oedema Weight Body temperature Standard clinical signs: stool, vomiting, dehydration, cough, respiration and liver size, eyes, ears, skin condition and peri-anal lesions are assessed MUAC each week Length or height is taken after 21 days Other records: e.g., absent, vomits or refuses a feed A full medical examination is done every two days 4.5.4 Progression from Rehabilitation Phase to Discharge Based on the child fulfilling the discharge criteria, a decision can be made to discharge the child to his/her home or for referral to supplementary feeding or other health, nutrition and livelihood services that seek to address some of the underlying causes of malnutrition at the household level. Box 9. Discharge Criteria from Inpatient Care Rehabilitation Phase 15 percent weight gain maintained for two consecutive days (of admission weight or weight free of oedema) (see Annex 5. Guidance Table to Identify Target Weight for Discharge) No bilateral pitting oedema for two weeks Clinically well and alert Additional concerns: Nutrition and health education scheme completed Immunisation schedule updated Adequate arrangements for linking caregiver and child with appropriate community initiatives (e.g., supplementary feeding) and for follow-up made  Criteria to Move Back from the Rehabilitation Phase to the Stabilisation Phase in Inpatient care If a child develops any signs of a medical complication, he/she should be referred back to the stabilisation phase. Routine drugs are individually prescribed depending upon what has already been given and the cause of the referral (see Annex 17. Action Protocol in Outpatient Care). 4.6 Failure to Respond to Treatment in Inpatient Care Some children undergoing inpatient care may show failure to respond to treatment or exhibit deterioration in condition at different stages of the treatment. Criteria for defining failure to respond to treatment are listed in Table 16. Failure to achieve initial improvement at the expected rate is termed primary failure to respond to treatment. This can be attributed to unrecognised infection or drug-resistant infections such as bacterial (TB), viral (measles, hepatitis B, HIV) or parasitic (malaria) infections. Deterioration in a childs condition after a satisfactory response has been established is termed secondary failure to respond to treatment. This secondary failure may be due to acute infection contracted during inpatient care, reactivation of infection as immune and inflammatory responses recover, or insufficiency in essential nutrients in the diet provided to the child. Table 16. Criteria for Defining Failure to Respond to Treatment in Inpatient Care Primary failure* to respond to treatmentTime after admissionFailure to regain appetite4 - 7 daysOedema is not reducing4 - 7 daysOedema is still present10 daysFailure to enter rehabilitation phase or outpatient care10 daysSecondary failure* to respond to treatmentDuring rehabilitation phaseFailure to gain more than 5g/kg bodyweight/day for 2 successive daysStatic weight for 3 successive days* Primary failure to respond means when the criterion has been noticed since admission. Secondary failure to respond means when the child has shown improvement and then later deteriorates as described by the criterion. A child who is undergoing treatment for SAM meeting any of the above criteria should be diagnosed as failing to respond to treatment. When such a diagnosis is made, an extensive medical evaluation of the child must be carried out (i.e., medical history, physical examination, laboratory investigations of urine and stool samples). The overall management of these cases should be reviewed (e.g., evaluation of adherence to treatment protocol, availability of trained staff). Failure to respond to treatment should be recorded on the individual treatment chart and the child should be scheduled to be seen by more senior and experienced staff. Furthermore, corrective measures should be taken to strengthen specific areas that need improvement in the practice of managing SAM while ensuring that treatment protocols are adhered to and that staff receives adequate supervision. 4.6.1 Care for Children Failing to Respond to Treatment in Inpatient Care When a child shows signs of failure to respond to treatment, the causal factors contributing to this situation should be thoroughly investigated and the child should be treated appropriately according to the recommendations in these guidelines. The most frequent causes of failure to respond to inpatient treatment are listed in Box 10. The child that fails to respond should receive a thorough medical examination. The following laboratory investigations are recommended: Urine analysis for pus cells and culture Blood screening and culture Screening for TB Stool test for trophozoites and cysts of Giardia HIV test according to the national guidance Malaria screening Hepatitis screening Primary Failure to Respond to Treatment Every child with unexplained primary failure to respond should have a detailed medical history and examination performed. In particular, the child should be assessed carefully for infection as follows: Examine the child carefully. Measure the temperature, pulse rate and respiration rate. Where appropriate, examine urine for pus cells and culture blood. Examine and culture sputum or tracheal aspirate for TB, examine the fundi for retinal TB and do a chest x-ray. Examine stool for blood and look for trophozoites or cysts of Giardia. Culture stool for bacterial pathogens. Test for HIV, hepatitis and malaria. Culture and examine the cerebrospinal fluid. Secondary Failure to Respond to Treatment Secondary failure to respond to treatment is a deterioration/regression in condition after having progressed satisfactorily to the rehabilitation phase with a good appetite and weight gain. It is usually due to: Inhalation of diet into the lungs: Children with SAM often have poor neuromuscular coordination between the muscles of the throat and the oesophagus. It is quite common for children to inhale food into their lungs during recovery if they are: 1) force-fed, particularly with a spoon or pinching of the nose; 2) laid down on their back to eat; and/or 3) given liquid diets. Inhalation of part of the diet is a common cause of pneumonia in all malnourished patients. Patients should be closely observed while being fed by the caregiver to ensure that the correct feeding technique is being used. One of the advantages of RUTF is that it is much less likely to be force-fed and inhaled. An acute infection that has been contracted in the health facility (called a nosocomial infection) from another patient or at home from a visitor/sibling/household member. At times, as the immune and inflammatory system recovers, there appears to be a reactivation of infection during recovery. Acute onset of malaria and TB (for example sudden enlargement of a cervical abscess or development of a sinus infection) may arise several days or weeks after starting a therapeutic diet. A limiting nutrient in the body that has been consumed by the rapid growth and is not being supplied in adequate amounts by the diet: This is very uncommon with modern diets (F100 and RUTF), but could occur with home-made diets or with the introduction of other foods. Frequently, introduction of the family diet slows the recovery rate of a severely malnourished child. The same can occur at home when the child is given family food or traditional complementary foods that are inadequate in Type 1 and Type 2 nutrients. 4.6.2 Action Required When a Child Fails To Respond to Treatment in Inpatient Care Keep accurate records of all children who fail to respond to the treatment and of those who died. These records should include, at a minimum, detail of the childs age, sex, date of admission, MUAC, WFH, weight on admission, principal diagnosis, treatment and, where appropriate, date and time of death, and apparent cause of death. Always systematically examine the common causes of failure to respond and death and identify areas where case management practices should be improved in order to rectify the problems. If these actions are not immediately successful, an external evaluation by someone experienced with the inpatient care of SAM should be conducted. An investigation into the organisation and application of the protocol for treatment should be carried out as part of the evaluation. Review the supervision of staff with refresher training, if necessary. Recalibrate scales (and length-boards).  SHAPE \* MERGEFORMAT  4.7 Criteria for Discharge from Inpatient Care After Full Recovery The child is fully recovered if the following discharge criteria are met: 15 percent weight gain maintained for two consecutive days (of admission weight or weight free of oedema) (see Annex 5. Guidance Table to Identify Target Weight for Discharge) No bilateral pitting oedema for two consecutive weeks Clinically well and alert It is recommended that the following elements are considered at discharge: Health and nutrition education scheme is completed Appropriate weaning of RUTF is reached Immunisation schedule is updated Adequate arrangements for linking caregiver and child with appropriate community initiatives (e.g., supplementary feeding) and for follow-up are made Other children that are discharged but did not meet the discharge cured criteria (thus did not recover) are children who: Died while in treatment Defaulted, or were absent for two days Did not recover or did not meet the discharge criteria after two months in treatment 4.8 Discharge Procedures The following elements should be addressed before the child is discharged: Provide feedback to the caregiver on the final outcome of treatment Counsel caregiver on good feeding and care practices, including on providing and preparing appropriate complementary food Ensure caregiver understands importance of follow-up care to prevent relapse (e.g., enrolment in supplementary feeding and other child health and nutrition programmes) Note discharge outcome in register and treatment card Advise the caregiver to immediately go to the nearest health facility if child refuses to eat or has any of the following signs: High fever Frequent watery stools or stools with blood, diarrhoea lasting more than four days Difficult or fast breathing Vomiting Not alert, very weak, unconscious, convulsions Bilateral pitting oedema Ideally, children discharged from CMAM should be referred to supplementary feeding, where available, for a minimum of three-to-four months, regardless of their nutritional status. 4.9. Infant and Young Child Feeding Support Annex 19. Health and Nutrition Education Messages summarizes health and nutrition education messages that can be used for individual and group counselling for improving and supporting IYCF practices. It provides a list of key behaviours to promote, summarizes the importance of breastfeeding for the infant and young child, and recommends IYCF practices on breastfeeding and complementary feeding. It also provides an example of a countryadapted tool for recommended foods for infants and young children. 5. Inpatient Care for the Management of SAM for Infants Under 6 Months Infants under 6 months with SAM should be treated within the context of IYCF recommendations. Breastfeeding support is an integral component of therapeutic care for severely malnourished infants. This support includes protection and support for early, exclusive and continued breastfeeding. Hence support to the mother on maternal feeding and care practices is crucial in the management of acute malnutrition in infants. Infants under 6 months with SAM are always admitted to inpatient care. They need special care and ideally should be separated from the other older infants and children with SAM. The main objective of treatment of these infants is to improve or re-establish breastfeeding; provide temporary or longer-term appropriate medical and dietary treatment; and provide nutrition, psychological and medical care for their caregivers. They are not offered RUTF as it is not suitable for infants under 6 months because the reflex of swallowing semi-solid foods is not yet present. Infants under 6 months with SAM who are not breastfed are particularly at risk and will need protection and support to reduce the risks of artificial feeding. For these infants and their caregivers, the potential for restoring or establishing breastfeeding should always be explored to the maximum. Problems related to feeding that lead to SAM in infants that will need to be addressed include: Lack of breastfeeding; partial breastfeeding Inadequate unsafe artificial feeds Mother dead or absent Mother malnourished or traumatised, ill or unable to respond normally to her infants needs Disability that affects the infants ability to suckle or swallow, and/or a developmental problem affecting infant feeding This section provides guidance on treatment of the two categories of children under 6 months: Breastfed infants or infants under 6 months with SAM with lactating female caregiver Non-breastfed infants: infants under 6 months with SAM without the prospect of being breastfed Infants with SAM over 6 months with a bodyweight below 4 kg will follow the same treatment protocol. Infants with SAM of HIV-positive mothers are treated for SAM according to the international guidance on the prevention of mother-to-child transmission of HIV (PMTCT). 5.1 Breastfed Infants Under 6 Months WITH a (Potential) Lactating Mother (or Caregiver for Wet Nursing) 5.1.1 Admission Criteria Infants under 6 months being breastfed, if the infant: Has a presence of bilateral pitting oedema Has visible wasting Is at high risk of SAM because of inadequate feeding of infant or lactating mother Note: Infants under 6 months with SAM and their lactating mothers (or wet nurses) are both treated and taken care of. In food insecure environments or an emergency situation, they are at high risk of SAM, so it is important to include the following criteria: Infant unable to suckle effectively (e.g., too weak) Infant not satisfactory gaining weight at home despite breastfeeding counselling Lactating mother (or wet nurse) with insufficient breast milk Malnourished lactating mother (or wet nurse) Absent lactating mother 5.1.2 Routine Medicines and Supplements Antibiotics No antibiotic treatment is provided unless there are signs of infection. If there is any sign of infection, give Amoxicillin (for infants weighing a minimum of 2 kg) 30 mg/kg bodyweight, two times a day (60 mg/kg bodyweight/day) in association with Gentamycin 7.5 mg/kg bodyweight/day IM or IV for seven days. Note: Do not use Chloramphenicol in young infants under 2 months, and use with caution in infants 2-5 months. The Appendix provides detailed guidance on the management of medical complications in the presence of SAM. Folic Acid Give 2.5 mg (tablet crushed) in a single dose. Ferrous Sulphate Give F100-Diluted, as F100 has already been enriched with ferrous sulphate and it is easier and safer than to calculate and add ferrous sulphate to very small amounts of feeds. F100 with one-third water makes the F100-Diluted (see Feed Preparation in Section 5.1.3). 5.1.3 Dietary Treatment The main objective is to restore exclusive breastfeeding. Therefore, stimulate and support breastfeeding and supplement the childs breastfeeding with therapeutic milk while stimulating production of breast milk. Breastfeed on demand or offer breastfeeding every three hours for at least 20 minutes (more if the child cries or demands more). The infant should be breastfed as frequently as possible. Between one half and one hour after a normal breastfeeding session, give maintenance amounts of therapeutic milk. Provide F100-Diluted for infants with severe wasting. F100-Diluted has a lower osmolarity than F75 and thus is better adapted to immature organ functions. Also, the dilution allows for providing more water for the same energy with a better carbohydrate to lipid ratio. (See Annex 11. Dietary Treatment.) Provide F75 for infants with bilateral pitting oedema and change to F100-Diluted when the oedema is resolved. Note: To prevent hypernatraemia in hot climates, sips of water or 10 percent sugar-water solution are given in addition to the milk diet until the thirst of the child is satisfied (see Hypernatraemic Dehydration in the Appendix). Quantities of F100-Diluted F100-Diluted is given at 130 ml/kg bodyweight/day, distributed across eight feeds per day. Use the look-up tables (Table 17) for maintenance amounts of F100-Diluted to give to infants using the supplementary suckling technique. The quantity of F100-Diluted is not increased as the child starts to gain weight. F100-Diluted provides 130 kcal/kg bodyweight/day. Regulation of Amount of F100-Diluted Given The progress of the infant is monitored by the daily weight. If the infant loses weight or has a static weight over three consecutive days but continues to be hungry and is taking all the F100-Diluted, add 5 ml extra to each feed. Maintenance amounts of F100-Diluted are given using the supplementary suckling technique. If the volume of F100-Diluted being taken results in weight loss, either the maintenance requirement is higher than calculated or there is significant malabsorption. In general, supplementation is not increased during the stay in the health facility. If the infant grows regularly with the same quantity of milk, it means the quantity of breast milk is increasing. If, after some days, the child does not finish all the supplemental feed, but continues to gain weight, it means the intake from breast milk is increasing and the infant is taking adequate quantities to meet his/her requirements. The infant should be weighed daily with a scale graduated to within 10 g (or 20 g). Table 17. Look-Up Table for Maintenance Amounts of F100-Diluted (Severe Wasting) or F75 (Bilateral Pitting Oedema Until the Oedema is Resolved) for Breastfed Infants Childs Weight (kg) F100-Diluted or F75 in case of oedema (ml per feed if 12 feeds per day)F100-Diluted or F75 in case of oedema (ml per feed if 8 feeds per day)e" 1.220251.3  1.525301.6  1.730351.8  2.130402.2  2.435452.5  2.740502.8  2.940553.0  3.445603.5  3.950654.0  4.45070 Once Infant is Gaining Weight at 20 g per Day (Absolute Weight Gain) Gradually decrease the quantity of F100-Diluted by one-third of the maintenance intake so that the infant gets more breast milk. If the weight gain of 10 g per day is maintained for two-to-three days (after gradual decrease of F100-Diluted), stop F100-Diluted completely. If the weight gain is not maintained, increase the amount of F100-Diluted given to 75 percent of the maintenance amount for two-to-three days, then reduce it again if weight gain is maintained. Once the infant is gaining weight at 20 g per day on breastfeeding, the child is ready for discharge. If the caregiver is agreeable, it is advisable to keep the infant in the health facility for an additional three-to-five days on breast milk alone to make sure that he/she continues to gain weight. If the caregiver wishes to go home as soon as the infant is taking the breast milk with increased demand, they should be discharged. When it is certain that the child is gaining weight on breast milk alone, he/she should be discharged, no matter what his/her current weight or weight-for-length. Feed Preparation For a large number of children: Add one packet of F100 to 2.7 L of water instead of 2 L. This is referred to as F100-Diluted. For a small number of children Add 35 ml of water to 100 ml of F100 already prepared, which will yield 135 ml of F100-Diluted. Discard any excess milk after use. Do not make smaller quantities. If you need more than 135 ml, use 200 ml of F100 and add 70 ml of water to make 270 ml of F100-Diluted and discard any excess milk after use. If F100 is not readily available, these infants can be fed with the same quantities of commercial infant formula diluted according to the instructions on the tin. If there is a range of milk formulas to chose from, use a formula designed for premature infants. However, infant formula is not designed to promote rapid catch-up growth. Unmodified powdered whole milk should not be used. Feeding Procedure Ensure good breastfeeding through good attachment and effective suckling. Avoid distractions and let the infant suckle the breast at his/her own speed. Build the mothers confidence to help milk flow. Encourage more frequent and longer breastfeeding sessions to increase milk production and remove any interference that might disrupt breastfeeding. Use the supplementary suckling technique to provide maintenance amounts of F100-Diluted. OR, feed by cup and saucer or NGT by drip (using gravity not pumping). Only feed with a NGT when the infant is not taking sufficient milk by mouth. The use of NGT should not exceed three days and should be used in the stabilisation phase only. Feeding Technique Use the supplementary suckling technique to re-establish or commence breastfeeding and also to provide maintenance amounts of F100-Diluted to severely malnourished infants. This technique entails the infant sucking at the breast while also taking supplementary F100-Diluted from a cup through a fine tube that runs alongside the nipple. The infant is nourished by the supplementary F100-Diluted while suckling stimulates the breast to produce more milk. The steps required in using the supplementary suckling technique are simple. The caregiver holds a cup with the F100-Diluted. The end of a NGT (size n8) is put in the cup and the tip of the tube is placed on the breast, at the nipple. The infant is offered the breast with the right attachment. The cup is placed 5-10 centimetres (cm) below the level of the nipple for easy suckling. When the child suckles more strongly, the cup can be lowered to up to 30 cm. After feeding is completed, the tube is flushed through with clean water using a syringe. It is then spun (twirled) rapidly to remove the water in the lumen of the tube by centrifugal force. If convenient, the tube is then left exposed to direct sunlight. Figure 5. Supplementary Suckling Technique  5.1.4 Individual Monitoring The following parameters should be monitored daily and entered on the individual treatment card: Weight Degree of bilateral pitting oedema (0 to +++) Body temperature (twice per day) Standard clinical signs: stool, vomiting, dehydration, cough, respiration, liver size, eyes, ears and skin condition Length or height (taken after 21 days when a new treatment card is used) Any other record: e.g., absent, vomits or refuses a feed, whether the child is fed by NGT or given IV infusion or transfusion As soon as the infant is 6 months of age and greater than 4 kg, the infant falls into the management criteria for the age group 6-59 months. If the infant still has SAM (fulfilling the admission criteria), introduce RUTF and refer to outpatient care. 5.1.5 Supportive Care for Mothers Supportive Care for Breastfeeding Mothers Supportive care for breastfeeding mothers should be provided, especially in very stressful situations. Focus needs to be directed at creating conditions that will facilitate and increase breastfeeding, such as establishing safe breastfeeding corners for mothers and infants, one-to-one counselling and mother-to-mother support. Traumatised and depressed women may have difficulty responding to their infants and require mental and emotional support which should also support an increase in breastfeeding. It is important to assess nutritional status of the mother (MUAC and bilateral pitting oedema). Explain to the mother the different steps of treatment that their child will go through. Efforts should be made to strengthen the mothers confidence and discourage self-criticism for perceived inability to provide adequate breast milk. Always alert the mother about the risk of pregnancy during breastfeeding amenorrhea. Adequate Nutrition and Supplementation for Breastfeeding Mothers Breastfeeding women need about 450 kcal per day of extra energy. Essential micronutrients in breast milk are derived from the mothers food or micronutrient supplement. Therefore it is important that the mothers nutrient and energy needs are met. The mother should consume at least 2,500 kcal per day. It is suggested that the health facility should provide nutritious food for the mother. The mother should also receive vitamin A (200,000 IU, unless there is a risk of pregnancy) if the infant is under 2 months. Dehydration may interfere with breast milk production. It is therefore important to ensure that the mother drinks at least 2 L of water per day. Psychosocial Care of the Mother Psychosocial care is a very essential component of the care for the mother and for the infant with SAM as the mother may have many problems of physical or psychological origin. These problems could affect her care of her infant or lead to defaulting. Table 18 demonstrates some of the mothers difficulties. The mother should receive a thorough explanation of her childs problem and how to manage it. She should be guided through a breastfeeding session and the supplementary suckling technique. The mother should also be counselled on social problems and receive a medical check if necessary. Advice on hygiene and the correct way to breastfeed should be provided to the mother in a supportive, participatory way through individual counselling or group discussions to relieve her stress and fears. Table 18. Possible Difficulties Encountered by Mothers of Infants with SAM Mother DifficultiesAction PointsNutrition and fluid intakeProvide enough fluid and balanced food; Screen the mother for malnutritionPhysical and mental healthProvide medical advice whenever requestedPhysical difficulties related to breastfeedingTreat sore nipples, cracked nipples and mastitis with breastfeeding counsellingMisinformation and misconceptionsEstablish good communication with the mother 5.1.6 Discharge Criteria Infants under 6 months or less than 4 kg being breastfed: Successful re-lactation with effective suckling results in minimum 20 g weight gain per day on breast milk alone for five days No bilateral pitting oedema for two weeks Clinically well and alert, and has no other medical problem Note: Upon discharge, confirm that the mother has been adequately counselled and has received the required amounts of micronutrient supplements during the stay at the health facility and for use at home. 5.1.7 Follow-Up After Discharge Follow-up for these children is very important. In areas where services are available, the mother should be included in a supplementary feeding programme (SFP) and receive high-quality food with the right balance of nutrients to improve the quantity and quality of breast milk. It is also important to monitor the infants progress and support breastfeeding and the introduction of complementary food at the appropriate age of 6 months. 5.2 Infants Under 6 Months Without the Prospect of Breastfeeding While the aim of the treatment of infants under 6 months with SAM with a caregiver with a potential of breastfeeding is to decrease F100-Diluted gradually until they are gaining sufficient weight on breast milk alone, the aim of the treatment of infants under 6 months with SAM without the prospect of being breastfed in [COUNTRY] is to receive F100-Diluted or infant formula until they are old enough to take semisolid complementary food in addition to adapted cow milk. (See Annex 15. Use of Home-Modified Cow Milk for Replacement Feeding in Case of No Access to Infant Formula.) If infants under treatment still have signs of SAM at the age of 6 months and have a weight greater than 4 kg, these infants will move to the 6-59 months age group and continue the treatment accordingly (see Admission Criteria for Children 6-59 Months in Annex 2. Admission and Discharge Criteria to CMAM for Children Under 5). 5.2.1 Admission Criteria Infants under 6 months not being breastfed (neither lactating mother nor wet nurse), if the infant has: Presence of bilateral pitting oedema Visible wasting 5.2.2 Stabilisation Phase Antibiotics No antibiotic treatment is provided unless there are signs of infection. If there is any sign of infection, give Amoxicillin (for infants weighing a minimum of 2 kg) 30 mg/kg bodyweight two times per day (60 mg/kg bodyweight/day) in association with Gentamycin 7.5 mg/kg bodyweight/day IM or IV for seven days. Note: Do not use Chloramphenicol in young infants under 2 months, and use with caution in infants 2-6 months. The Appendix provides detailed guidance on the management of medical complications in the presence of SAM. Folic Acid Give 2.5 mg (tablet crushed) in a single dose. Ferrous Sulphate Give F100-Diluted, as F100 has already been enriched with ferrous sulphate, and it is easier and safer to use F100-Diluted than to calculate and add ferrous sulphate to very small amounts of feeds. F100 with one-third addition water added makes the F100-Diluted (see Feed Preparation in Section 5.1.3). Dietary Treatment Infants under 6 months with wasting (marasmus) should be given F100-Diluted in the stabilisation phase with cup and saucer. Never provide F100 full-strength or RUTF. Infants under 6 months with bilateral pitting oedema (kwashiorkor) should always be given F75 until the oedema has resolved and then switch to F100-Diluted. Note: Supplement the milk diet with sips of water or 10 percent sugar-water solution until the thirst of the child is satisfied to prevent hypernatraemia. Quantities of F100-Diluted or F75 to Give Use the look-up table (Table 19) for amounts of F100-Diluted or F75 to give for non-breastfed infants under 6 months in the stabilisation phase. Amount given should be calculated based on 130 kcal/kg bodyweight/day. Table 19. Stabilisation Phase Look-Up Table for Volume of F100-Diluted (Severe Wasting) or F75 (Bilateral Pitting Oedema) for Non-Breastfed Infants Under 6 Months Childs Weight (kg) F100-Diluted or F75 in case of oedema (ml per feed if 12 feeds per day)F100-Diluted or F75 in case of oedema (ml per feed if 8 feeds per day)d" 1.525301.6  1.830351.9  2.130402.2  2.435452.5  2.740502.8  2.940553.0  3.445603.5  3.950654.0 4.45070 Feed Preparation For a large number of children: Add one packet of F100 to 2.7 L of water instead of 2 L for F100-Diluted. For a small number of children Add 35 ml of water to 100 ml of F100 already prepared to yield 135 ml of F100-Diluted. Discard any excess milk after use. Do not make smaller quantities. If you need more than 135 ml, use 200 ml of F100 and add 70 ml of water to make 270 ml of F100-Diluted and discard any excess milk after use. Feeding Procedure Feed by cup and saucer or NGT by drip (using gravity not pumping). Only feed with NGT when the infant is not taking sufficient milk by mouth. The use of NGT should not exceed three days and should be used in the stabilisation phase only. Feeding Technique Apply the correct feeding technique (see Feeding Technique in Section 4.3.2). It is important to ensure the infant has adequate intake. Individual Monitoring The following parameters should be monitored daily and entered on the individual treatment card: Weight Degree of bilateral pitting oedema (0 to +++) Body temperature (twice per day) Standard clinical signs: stool, vomiting, dehydration, cough, respiration, liver size, eyes, ears and skin condition Length or height after 21 days Any other record: e.g., absent, vomits or refuses a feed, whether the child is fed by NGT or is given IV infusion or transfusion Criteria to Progress from the Stabilisation Phase to the Transition Phase The criteria to progress from the stabilisation phase to the transition phase are both: Return of appetite Beginning of loss of oedema, which is normally judged by an appropriate and proportionate weight loss as the oedema starts to subside; children with severe bilateral pitting oedema (+++) should remain in the stabilisation phase until their oedema has reduced to moderate (++), as they are particularly vulnerable 5.2.3 Transition Phase Routine Medicines and Supplements See Section 5.1.2. Dietary Treatment Use the standard protocol for older children in transition phase with the following modifications: Only F100-Diluted should be used. The volume of the F100-Diluted feeds is increased by one-third in comparison to the stabilisation phase. F100-Diluted provides 130 kcal/kg bodyweight/day. Use the look-up table (Table 20) for the amounts of F100-Diluted to give to non-breastfed infants in the transition phase. Individual Monitoring Continue surveillance as outlined in the stabilisation phase (see Section 5.2.2). Criteria to Progress from the Transition Phase to the Rehabilitation Phase A good appetite: taking at least 90 percent of the F100-Diluted prescribed for the transition phase, and Complete loss of bilateral pitting oedema, or Minimum stay of two days in the transition phase for wasted children, and No other medical problem Table 20. Transition Phase Look-Up Table for Volume of F100-Diluted for Non-Breastfed Infants Childs Weight (kg)F100-Diluted (ml per feed if 8 feeds per day)d" 1.5451.6  1.8531.9  2.1602.2  2.4682.5  2.7752.8  2.9833.0  3.4903.5  3.9964.0  4.4105 5.2.4 Rehabilitation Phase Dietary Treatment Use the standard protocol for older children in the rehabilitation phase with the following modifications: Only F100-Diluted should be used. During the rehabilitation phase, infants receive twice the volume per feed of F100-Diluted than was given during the stabilisation phase. F100 provides 130 kcal/kg bodyweight/day. Use the look-up table (Table 21) for amounts of F100-Diluted to give to non-breastfed infants in the rehabilitation phase. Table 21. Rehabilitation Phase Look-Up Table for Volume of F100-Diluted for Non-Breastfed Infants Childs Weight (kg)F100-Diluted (ml per feed if 6-8 feeds per day)d" 1.5601.6  1.8701.9  2.1802.2  2.4902.5  2.71002.8  2.91103.0  3.41203.5  3.91304.0  4.4140 Individual Monitoring Continue with rehabilitation phase surveillance as outlined in the treatment of older children in Section 6. 5.2.5 DISCHARGE CRITERIA Infants under 6 months or less than 4 kg not being breastfed: 15 percent weight gain maintained (of admission weight or weight free of oedema) No bilateral pitting oedema for two weeks Clinically well and alert Other Considerations: At discharge infant can be switched to infant formula Caregiver has been adequately counselled 5.2.6 FOLLOW UP Continuity of care after discharge is important. Follow-up with these infants is needed to supervise the quality of recovery and progress, and to educate the caregivers. It is also important to support introduction of complementary food at the appropriate age of 6 months. 5.3 Infant and Young Child Feeding Support Annex 19. Health and Nutrition Education Messages summarizes health and nutrition education messages that can be used for individual and group counselling for improving and supporting IYCF practices. It provides a list of key behaviours to promote, summarizes the importance of breastfeeding for the infant and young child, and recommends IYCF practices on breastfeeding and complementary feeding. It also provides an example of a countryadapted tool for recommended foods for infants and young children. 6. Inpatient Care for the Management of SAM in Older Age Groups In exceptional cases, older children, adolescents and adults with SAM will also be admitted in inpatient care until full recovery. The physiological changes and principles of the management of SAM for children over 5 years, adolescents and adults are similar to those in children 6-59 months. However, there are differences in indicator use and index cutoffs. Moreover, for adolescents and adults there are differences in the diagnosis of bilateral pitting oedema and of acute weight. The amount of therapeutic food and drug dosages, and discharge of treatment is also adapted. In adolescents and adults, SAM occurs as a primary disorder in extreme conditions of privation and famine, or in association with other illnesses. In the latter case, both the primary illness and the acute malnutrition must be treated. Also, it is important to assess if the person has been losing weight in the past four weeks to determine if the wasted condition is a result of an acute weight loss or catabolic state, as this condition is more associated with increased risk of death. Adolescents and adults do not always associate wasting or bilateral pitting oedema with their diet. As a consequence, they do not necessarily understand that altering their diet will help them. Even in famine conditions, they are often very reluctant to eat anything except traditional foods, which they view as perfectly satisfactory. Moreover, pregnant and lactating women often have food restrictions based on cultural and religious beliefs. 6.1 Admission Criteria in Older Age Groups Box 11. Admission Criteria for Inpatient Care for the Management of Sam in Older Age Groups Older Children 5-9 Years Bilateral pitting oedema or severe wasting Adolescents 10-18 Years Bilateral pitting oedema or severe wasting (acute weight loss) depending on history and thorough examination to exclude secondary malnutrition Adults Bilateral pitting oedema or severe wasting (acute weight loss) depending on history and thorough examination to exclude secondary malnutrition 6.1.1 Older Children 5-9 Years Bilateral Pitting Oedema In children 5-9 years, examine the ankles and lower legs for presence of bilateral pitting oedema. Severe Wasting The preferred indicator for severe wasting is MUAC < 135 mm. Also, body mass index (BMI)-for-age < -3 z-score could be used to indicate severe wasting (see Annex 3. Anthropometric Measurements and Annex 4. Anthropometry Look-Up Tables). Note: Children 5-9 years with SAM will follow the same SAM treatment protocol and discharge criteria from treatment based on 15 percent weight gain (of admission weight or weight free of oedema) as children 6-59 months with SAM treated in inpatient care until full recovery (see Section 4). 6.1.2 Adolescents 10-18 Years Bilateral Pitting Oedema Examine adolescents ankles and lower legs for presence of bilateral pitting oedema. Non-nutritional causes of oedema can readily be identified by the history, physical examination and urinalysis. Severe Wasting (Acute Weight Loss) The preferred indicator for severe wasting in adolescents with acute weight loss is MUAC < 160 mm.29 Also, BMI-for-age < -3 z-score could be used to indicate severe wasting in adolescents (see Annex 3. Anthropometric Measurements and Annex 4. Anthropometry Look-Up Tables). 6.1.3 Adults Bilateral Pitting Oedema Examine adults ankles and lower legs for bilateral pitting oedema. If symmetrical oedema is present, its cause must be determined. In addition to malnutrition, causes in adults include pre-eclampsia in pregnant women, severe proteinuria (nephritic syndrome), nephritis, acute filariasis (the limb is hot and painful), heart failure, and wet beriberi. Non-nutritional causes of oedema can readily be identified by the history, physical examination and urinalysis. Severe Wasting (Acute Weight Loss) The preferred indicator for severe wasting in adults with acute weight loss is MUAC < 185 mm.29 Also, BMI < 16.0 kg/m2 could be used to indicate severe wasting in adults, (excluding or adjusted for) pregnant women and postpartum mothers (see Annex 3. Anthropometric Measurements and Annex 4. Anthropometry Look-Up Tables). 6.2 The Management of SAM in Adolescents and Adults 6.2.1 Stabilisation Phase A thorough examination should be conducted to exclude conditions that give rise to secondary malnutrition. A careful dietary history should be taken. Blood sugar should be tested to exclude diabetes mellitus. Give routine antibiotics and, except for pregnant women, a single dose of 200 000 IU of vitamin A orally after week four in treatment or upon discharge. Give the same dietary treatment as children 6-59 months with F75 and F100, but with adapted amounts. The initial goal of treatment is to prevent further loss of tissue. The amount of feed given per kg of bodyweight is much less than for children and decreases with increasing age, reflecting the lower energy requirements of adults. Recommended amounts for different ages are given in Table 22. These amounts will meet all nutrient requirements of adolescents and adults. As most severely malnourished adults are anorexic, the formula is usually given by NGT during the first few days. Treat hypothermia and hypoglycaemia, as adults and adolescents are susceptible to them. The latter condition is managed as described for children (see Appendix). Table 22. Dietary Requirements of Adolescents and Adults in the Stabilisation Phase AgeDaily energy requirement*Volume of diet requiredIn yearsIn kcal/kg bodyweightF75 (ml/kg bodyweight/hour)F75 (ml/kg bodyweight if 8 feeds a day)F100 (ml/kg bodyweight /hour)F100 (ml/kg bodyweight if 8 feeds a day)7-10754.233.63.02411-14603.528,02.52015-18502.822.42.01619-75402.217.61.713.6> 75352.0161.512* Individual needs may vary by up to 30 percent from these figures. 6.2.2 Rehabilitation Phase An improving appetite indicates the beginning of rehabilitation. During rehabilitation, adolescents and adults usually become very hungry, often refusing the formula feed and demanding enormous amounts of solid food. When this happens, a diet should be given that is based on traditional foods, but with added combined mineral and vitamin complex (CMV). Also, a wide variety of foods is provided and the patients are allowed to eat as much as they want. If possible, continue to give the formula feed with the vitamin and mineral mixes between meals and at night. If necessary, present the formula feed as a medicine. 6.2.3 Failure to Respond to Treatment Failure to respond to treatment in adults and adolescents is usually due to an unrecognised underlying illness, a nutrient deficiency, or refusal to follow the treatment regimen. 6.2.4 Discharge Criteria Adolescents and adults can be discharged from the SAM treatment if they are eating well, have sustained weight gain and have a reliable source of nutritious food outside the health facility. They should be referred for treatment of any other health problem that has been diagnosed prior to discharge. 7. Monitoring and Reporting A well-designed monitoring and reporting (M&R) system is an essential component in CMAM. M&R focuses on children under 5 as they are the primary target group for treatment. With well-informed monitoring data, aspects of the management of SAM that need improvement can be identified in a timely manner. Appropriate action then can be taken to improve on individual care, organisation of care and overall quality of care. The CMAM M&R system encompasses individual monitoring of admission, treatment process and outcome. Service M&R of community outreach, inpatient and outpatient care sites individually, and of CMAM services combined involves timely collection of relevant information, aggregating and disaggregating at various levels of the system, and subsequent analysis and reporting. Monitoring is used to measure the monthly performance and report on effectiveness. Performance indicators of interest are recovery (cure rate), case fatality (death rate), defaulting (default rate), and non-recovery. Barriers to access for care and the degree of service uptake (coverage rate) are indicating how well the service or programme is reaching the target population and meeting the service needs. The objective of monitoring is to compare service performance against a set of objectives, and to make adjustments to the service based on an analysis of routine data that is collected on a monthly basis. It is also important to interpret the findings in the broader health and nutrition information context obtained from secondary sources. This section on the CMAM M&R system presents the specific M&R tools, describes the key indicators and provides guidance on support and supervision and minimal reporting. 7.1 Monitoring Tools Standardised M&R forms and tools are used to collect and aggregate community outreach, outpatient care and inpatient care monitoring data. This will facilitate comparability of data across different sites as well as aggregate data at the various administrative levels. 7.1.1 Registration Unique SAM Number All new admissions receive a unique SAM number that is maintained, even if a child is referred to another health facility or site. It helps in tracking a child across different services and for sharing of information. The unique SAM number should be used on all monitoring and referral forms pertaining to the child. It is indicated on the road to health card that could be provided to all children in treatment for SAM. The standard numbering system for unique SAM numbers is organised per state/region and uses the following format: XXX/9999/MMYY/ZZ XXX = Two- or three-letter code for health facility or site 9999 = Childs individual number MMYY = Month and year of admission ZZ = Two-letter code for start of treatment, OC is for outpatient care, IC is for inpatient care E.g.: ATH/0001/0109/IC is the first child admitted directly to inpatient care in Atlantis Teaching Hospital in January 2009. A system of coding all health facilities per state/region should exist or put into place. Registration Book The heath facility will record admissions in their regular registration book. The registration book is not used for monitoring the condition of the child, but only for recording admission and discharge. The following basic information is recorded: Registration number Unique SAM number Date of admission Name, age, sex, place of residence Date of discharge Outcome of treatment 7.1.2 Individual Monitoring Individual monitoring information of the childs health and nutrition condition is recorded on treatment cards. Individual monitoring of the childs health and nutrition condition is important in determining the progress of the treatment, and, in case of a sudden deterioration, responding with a life-saving intervention. Intensive daily monitoring is needed for the child with SAM in inpatient care. In outpatient care, the child with SAM is in a better condition, does not need the same level of health monitoring and is therefore monitored weekly. Analysis of the individual treatment cards helps to identify and highlight problems which might contribute to failure to respond to treatment. Also, it is important to systematically review the individual treatment cards during supervision visits to ensure that proper treatment is given and that protocols are being adhered to. Inpatient Care Treatment Card (See Annex 27) The childs information should be entered on the inpatient care treatment card. Medical history, physical assessment at admission and daily surveillance information should be recorded. This helps monitor the childs progress and inform decision-making during treatment. The outcome of the treatment is also marked on the card. Outpatient Care Treatment Card (See Annex 29) The childs information should be entered on the outpatient care treatment card upon admission and is updated during the weekly monitoring sessions. The outcome of the treatment is also marked on the card. Referral Form (See Annex 30) If the child is referred from inpatient care to outpatient care or vice versa, the caregiver is given a referral form together with instructions on how and when to go where. The best form to use is the IMCI referral form. If outpatient care treatment cards are made available at the inpatient care site, these can be filled at the inpatient care site and used as a referral form when the child moves from inpatient care to outpatient care. Filing System A filing system for treatment cards is kept at the health facility or site. A first file is for treatment cards of all those currently in treatment, including in a separate section the cards of the children referred for investigation. A second file is for treatment cards of those children who have been discharged, with separate sections for the cards of children who were cured, died, defaulted or non-recovered. 7.1.3 Service Monitoring Site Tally Sheet (See Annex 31) The site tally sheet indicates the name of the health facility and type of CMAM service; one sheet is used per service. Site tally sheets provide information on weekly new admissions, old cases admitted, discharges, internal movements and total cases under treatment. All children admitted to and discharged from CMAM or referred are tallied; gender is tallied for all new admissions only. The same site tally sheet is used in inpatient care or outpatient care. One site tally sheet covers a calendar month (indicating four or five weeks), is completed by the responsible health care provider at the end of each weekly session in outpatient care or weekly at inpatient care sites, and provides a monthly summary at the end of the month. Monthly summaries are used to fill the monthly site reporting sheet. Each health facility with an CMAM site should send the site tally sheet and/or site report to the state/regional MOH monthly. Site tally sheets are regularly checked by a supervisor for accuracy. The tally information can help identify differences in affected gender, age groups, type of SAM and trends. Admissions New Cases New admissions are categorised as: New admission 6-59 months New admission other age group: infant under 6 months, child over 5 years, adolescent or adult Admissions Old Cases Old cases that are admitted are: Referral from inpatient/outpatient care or from other site: Incoming referrals are children leaving the health facilitys site of treatment. They are not counted as a new admission as they were already in treatment elsewhere in the state. Returned defaulter: Returning defaulters are children who left the service before ending the treatment and return to continue their treatment (same episode). Discharges Discharges children 6-59 months are categorised as: Cured: Children who meet the discharge criteria Died: Children who died during treatment Defaulted: Children who defaulted during treatment: were absent for two days in inpatient care or for the third consecutive visit in outpatient care Non-recovered: Children who could not reach the discharge criteria as cured after two months in treatment in inpatient care or after four months in treatment in outpatient care; during the period in treatment they were referred for further investigation based on the action protocol Referrals to Another Site (Inpatient Care or Outpatient Care) Outgoing referrals are children leaving the site of treatment. They are not counted as discharged from the service as they are still under treatment since they have not yet reached the discharge criteria. They temporarily exit the current health facility to be referred to another health facility for continued treatment because their condition deteriorated or they did not respond to treatment. Upon return, they re-enter the site as a referral. Total Discharges Total discharges are all children 6-59 months that leave the site as cured, died, defaulted or non-recovered. The number of total discharges is used as a denominator to calculate performance indicators for the cured, death, defaulter and non-recovery rates. Total Exits Total exits is a number that indicates all children that exit the site that week and includes all children who are discharged (as cured, died, defaulted or non-recovered) and who are leaving the site as referrals. The number of total exits provides the total number in treatment at the respective site and is used for site planning. Total Number in Treatment Total number in treatment at the respective site is calculated and used for site planning. It also provides the start number for the next weeks tally column. Gender Gender is tallied for all children 6-59 months with SAM who enter as new admissions. Monthly Site Report (See Annex 32) The monthly site report is completed monthly with inputs from the site tally sheet. The disaggregated report provides a summary of quantitative information to assess performance, monitor trends and identify areas that require investigation at the health facility level: Total number in treatment at the beginning of the month Admissions as new cases Admissions as old cases (incoming referrals and returned defaulters) Total admissions of the month The number and proportion of children that are discharged cured, died, defaulted or non-recovered Total discharges (denominator for discharge rates) Total referrals Total exits Total number in treatment at the end of the month Gender distribution for all new admissions children 6-59 months Monthly site reporting sheets are regularly checked by a supervisor for accuracy. Note: Reporting is based on calendar months. Therefore one month will usually cover four weeks and occasionally five weeks. This has to be taken into consideration when interpreting changes in trends. MONTHLY District and State/Region Reports (See Annex 33) The district and state/region reports are completed monthly with inputs from all the site reports combining inpatient care and outpatient care. Information on referrals is not captured in this report, as referrals have remained in treatment within the district/state. The aggregated report does provide a summary of quantitative information to assess performance and monitor trends at the district or state/regional level: Total number in treatment at the beginning of the month Admissions as new cases Total admissions of the month The number and proportion of children that are discharged cured, died, defaulted or non-recovered Total discharges Total number in treatment at the end of the month Gender distribution for all new admissions only Note: Reporting is based on calendar months. Therefore one month will usually cover four weeks and occasionally five weeks. This has to be taken into consideration when interpreting changes in trends. Information on referrals is not captured in the aggregated monthly district or state/region report, as referrals have remained in treatment within the district or state. Community Outreach Report (See Annex 26) The community outreach reports summarize activities from community outreach activities based on routine monitoring or from point activities at the community level. The information collected informs the narrative report and provides a summary of the following information: Scale of the service Key indicators: Human resources: number of community outreach workers MOH staff; number of community outreach volunteers Training: number of community outreach workers including volunteers trained and active; number of community representatives oriented Community mobilisation: number of communities targeted and involved; number of communities meetings Community outreach activities: number of community screening sessions conducted; number of children with SAM identified and referred for treatment; number of community home visits for problem cases; number of community health and nutrition education sessions held CMAM service coverage Discuss the following: Barriers to access Reasons why areas are not covered Reasons for absentees and defaulting Reasons for non-response to treatment Causes of death Success stories Identified problems Planned activities Table 23 provides an overview of summary information on entry and exit categories for individual and service monitoring of children 6-59 months treated in CMAM. Table 23. Summary Entry and Exit Categories for Individual and Service Monitoring for Children 6-59 Months Inpatient Care Outpatient CareENTRY CATEGORIES 1. New admission: New case of child 6-59 months who meets the admission criteria -- including relapse after cure 2. Other new admissions: New case: infants, child, adolescent, adult (< 6 months or e" 5 years) who needs treatment of SAM in inpatient care 3. Referral from outpatient care: Condition of child deteriorated in outpatient care (according to action protocol) and child needs inpatient care Or Returned after defaulting (or Moved from other inpatient care site)*  1. New admission: New case of child 6-59 months who meets the admission criteria -- including relapse after cure 2. Other new admissions: New case who does not meet pre-set admission criteria but needs treatment of SAM in outpatient care (special case, based on decision of supervisor) 3. Referral from inpatient care: Case of child 6-59 months referred from inpatient care after stabilisation and continues treatment in outpatient care Or Returned after defaulting (or Moved from other outpatient care site)*EXIT CATEGORIES 1. Discharged cured: Child 6-59 months who meets discharge criteria, i.e., special cases that were not referred to outpatient care earlier 2. Discharged died: Child 6-59 months who dies while in inpatient care 3. Discharged defaulted: Child 6-59 months who is absent for two days 4. Discharged non-recovered: Child 6-59 months who remained in inpatient care does not reach discharge criteria after two months in treatment 5. Referred to outpatient care: Condition of child has stabilised, childs appetite has returned, the medical complication is resolving and the child is referred to outpatient care to continue treatment  1. Discharged cured: Child 6-59 months who meets discharge criteria 2. Discharged died: Child 6-59 months who dies while in outpatient care 3. Discharged defaulted: Child 6-59 months who is absent for three consecutive visits 4. Discharged non-recovered: Child 6-59 months who does not reach discharge criteria after four months in treatment 5. Referred to inpatient care: Condition of child has deteriorated or child is not responding to treatment (per the action protocol), and child is referred to inpatient care *Movement between sites is possible in mobile populations or during emergencies. Narrative Report (See Annex 34) The narrative report provides a summary of key information on: Scale of the service Key performance indicators Discussion on performance, including: Analysis of high and/or low performing sites Barriers to access Reasons for absentees, default, non-response to treatment and relapse Common causes of death Contextual information as appropriate, including context changes in relevant sectors such as food security, water and sanitation, health, and insecurity that may have an influence on service operation or performance Success stories Action plan for next month and support needed/planned to be given Quantitative information can be presented in figures if the capacity exists Some information may be collected monthly or periodically from sites if considered useful, calculated on all or a sample of treatment cards from discharged cured beneficiaries in a particular month: Average length of stay (LOS) (expressed in days) Average daily weight gain (AWG) (expressed in g/kg bodyweight/day) Referral rate Categories of admission, e.g., bilateral pitting oedema, severe wasting based on MUAC or WFH z-score 7.2 Performance Indicators There are three basic sets of indicators for measuring the performance of CMAM services for children 6-59 months, as described in the following sections: Output indicators measure whether an CMAM service has completed the planned activities needed to achieve the established objectives. They are measured as numbers. Process indicators directly measure the performance of key processes, which in this case relates to the CMAM treatment process. Outcome indicators measure whether an CMAM service has achieved its objectives and planned outcomes. They are measured as percentages. 7.2.1 Indicators Measuring Output Monthly output indicators: Number of functioning inpatient care and outpatient care sites (or number of health facilities with inpatient care and outpatient care sites) Number of health care providers trained in outpatient care and referral based on action protocol (plus gender distribution) Number of community outreach workers trained in community outreach (plus gender distribution) Number of communities mobilised (number of meetings) Report on use of F75, F100, RUTF, ReSoMal and CMV Total number of new admissions Total number of children under treatment 7.2.2 Indicators Measuring Process The following are process indicators that are measured monthly and/or periodically depending on capacity. Barriers to Access and Utilization Assessing this information can help identify problems with knowledge, attitudes and practice (KAP) on malnutrition and health service utilisation, and determine where strengthened support, training and mobilisation might be needed. It can also refine key messages on social and behaviour change and communication. Cause of Death Assessing and compiling this information can help identify problems with treatment and use of action protocols, and determine where strengthened support, training and supervision might be needed. Reasons for Absentees, Defaulting and Non-Response to Treatment Compilation of this information can help identify common reasons for default or non-response to treatment. Reasons for non-response might include a high prevalence of TB and/or HIV, the sharing of food in the household or poor access to water and sanitation. This information might indicate a need for stronger service linkages with other sectors. It is also important to understand the reasons for defaulting, barriers to accessing services and/or unrecorded death. Readmission after Discharge (or Relapse)  This can help service planners understand situations outside of the service. Interventions might be needed at the household level to avoid high readmission rates. High readmission rates might also indicate children are discharged too soon. Relapse is recorded on the childs treatment card and can be tallied monthly or periodically from the treatment cards. Average Length of stay (LOS) of Discharged Cured Length of stay (LOS) is the period in number of days that a child spends in treatment for SAM from admission to discharge. LOS in outpatient care is normally long and can take up to 60 days, but is expected to be shorter in inpatient care. Also, one child can cover both services. Average LOS reflects effectiveness of the CMAM services and is best disaggregated per use of service (i.e., outpatient care only, inpatient care only, both outpatient care and inpatient care). A long average LOS might be the result of, e.g., a high proportion of children who do not respond to treatment (non-responders or non-recovered), frequent absence, default, sharing of RUTF and/or unresolved illness. A short average LOS might indicate that children are discharged too soon. If there is a high relapse rate, this might be a possible cause. Average LOS is calculated on a sample of cured discharges for kwashiorkor and marasmus separately, as the sum of LOS divided by number of cards in the sample. Calculation: Average LOS = sum of LOS divided by number of cards in sample Average weight gain (AWG) of Discharged Cured Average weight gain (AWG) in outpatient care is expected to be greater than 4 g/kg bodyweight/day, while in inpatient care this could be better (as feedings are monitored and there is decreased chance of sharing or eating other foods that may interfere with the dietary treatment). A low AWG may indicate, e.g., high absence, default, ineffective treatment, sharing of RUTF and/or non-compliance to the treatment protocol. AWG is calculated on a sample of cured discharges for kwashiorkor and marasmus separately, as the sum of weight gains divided by number of cards in the sample. Calculation: Daily weight gain (g/kg bodyweight/day) = [discharge weight in g minus minimum weight in g] divided by [minimum weight in kg multiplied by the number of days between minimum weight and discharge day] Average daily weight gain = sum of weight gains (g/kg bodyweight/day) divided by number of cards in sample Referral Rate Children are referred from outpatient care to inpatient care per the action protocol in outpatient care (see Annex 17 Action Protocol in Outpatient Care) or from inpatient care to a higher level of care when their condition deteriorates or when the child is not responding to treatment. After treatment for the medical complication, the child returns to inpatient care and/or outpatient care to continue treatment for SAM. The child was not discharged from the SAM treatment, but had temporarily exited the respective SAM treatment site. The referral rate provides information on severity of cases that are admitted and/or non-response to treatment and hence highlights weaknesses in the care system (e.g., late presentation of cases, quality of care, endemic patterns). Calculation: Referral rate = Number of children referred per number of children in treatment during the time period of reporting 7.2.3 Indicators Measuring Outcome Monthly Outcome Indicators % discharged cured (cure rate) = proportion of children discharged cured of total discharged* % discharged died (death rate) = proportion of children who died when under treatment of total discharged* % discharged defaulted (default rate) = proportion of children recorded as absent for third consecutive week or outpatient care session of total discharged* % discharged non-recovered (non-recovery rate) = proportion of children who do not meet the discharge criteria after four months under treatment of total discharged* * Total number of discharged = cured + died + defaulted + non-recovered Note: Monthly outcome indicators are calculated for CMAM for children 6-59 months only. Inpatient care site reports only calculate these indicators if children 6-59 months remain in the CMAM inpatient care service until full recovery (large number of special cases or no outpatient care available) and if the numbers discharged are greater than 10. Otherwise, the results of the outcome indicators are maintained in proportions and not in percentages. Periodic Outcome Indicator Coverage Coverage is an indicator expressing service availability, access and uptake. It indicates how well a service is accessed and utilised. Currently, different methods exist to measure coverage for CMAM. The methods are being refined and adapted for routine implementation for measuring coverage of CMAM as an integrated service into national health systems. If coverage information is available, it is important to specify the methods used for estimating the service coverage. 7.3 Supportive Supervision As part of the M&R system, it is important to have focused attention on having a continuous quality improvement system in place. Supportive supervision of state/region or district health managers and health care providers in data collection, analysis and reporting helps to ensure accurate information at prescribed periods of time, and to ascertain both the quality of information and its usage to strengthen the quality of community outreach, inpatient care and outpatient care. Health care providers have job aids available at the health facility to guide them in implementing quality CMAM services (see Annex 41. List of Job Aids). Some of the job aids will be laminated or printed as wall charts, some will be in individual possession, and others will form part of the equipment at the health facility. Supervisors should perform regular supportive supervision visits and use a standardized checklist to systematically cover specific job functions to assess and address service performance (see Annex 35. Checklists for Supportive Supervision). At the same time, the supervisor is a mentor and he/she should use the opportunity to provide support to health care providers and community outreach workers based on their identified needs and observed needs, and strengthen capacities for improving quality. Supervision for improving quality of protocol implementation entails monitoring admission and discharge trends and adherence to protocols. Accurate recording and compilation of information regarding admissions, re-admissions and referrals, and discharges from outpatient care or inpatient care sites is important. Analysis of the outpatient care and inpatient care site data is essential for both supervisor and implementer as it provides important information about the performance of individual sites and can be used to ensure actions be taken to improve service quality. 7.3.1 Supervision of Services Supervisors should review the quality of services for the following (see Annex 35. Checklists for Supportive Supervision): Community mobilisation Community screening and follow-up of problem cases Completion of the treatment cards and other health documents Adherence to medical and dietary treatment protocols Progress of individual children, checking for consistent weight gain Referral between services Health and nutrition counselling M&R system: use and completion of tally sheets, monthly site reports and narrative reports Management of supplies Regularly reviewing treatment cards, particularly of those children under treatment and of those who have defaulted, died, who did not respond to treatment or did not recover, can identify weaknesses in community outreach, the management of individual cases, or service delivery. Treatment cards and site reports reveal if admissions and discharges are carried out according to the national guidelines, routine medicine and dietary treatments are administered correctly, and bilateral pitting oedema is properly assessed. They highlight if deterioration in the condition of the child is identified and acted upon according to the action protocol and whether these children who are not thriving are referred for medical investigation before they are discharged as non-recovered. Review findings should be discussed with implementing health care providers so that necessary improvements can be made. 7.3.2 Supervision of Operational Management of Sites Supervisors should review the following (see Annex 35. Checklists for Supportive Supervision): Organisational structure of service delivery Crowd management Supply flow and stock management for medicines and therapeutic foods Organisation of human resources Quality of health and nutrition group sessions at the health facility and in the communities Links with community outreach Links with other community services 7.3.3 Feedback of Information Health care providers and supervisors at outpatient care and inpatient care sites and those involved in community outreach should hold regular meetings to discuss performance using the monitoring data. Aggregated monitoring data should also be analysed and discussed at the district, state/region and national levels. Experiences should be shared, feedback given and action plans for improving performance developed and discussed. In outpatient care settings, feedback can be provided to the community through focus group discussions and community mobilisation activities. It is also recommended that feedback be provided to the community on a regular basis to gain trust and confidence in the new treatment and empower them to participate in the treatment of children with SAM. This may be done through regular focus group discussions. Focus groups should be carefully selected to ensure that specific issues are discussed with appropriate community representatives. These may be, e.g., community leaders, teachers, or beneficiaries and non-beneficiaries. Discussions should be a two-way process to allow for explanation of service protocols or specific issues and for the community to provide input into the services. Discussion topics could cover topics such as: perceptions of medical and dietary treatment, and why caregivers do not bring children to the outpatient sites or health facilities, and how this can be improved. 7.4 CMAM Information System The tally and/or site reports are sent to the district MOH on a monthly basis. The site reports from individual sites are compiled monthly into a monthly district and state/region report combining inpatient care and outpatient care, and reporting overall performance on the management of SAM. At the national level, reports from the district and state/region are compiled into a national SAM data repository. Analysis of site, district and state/region reports provides information about service performance for the management of SAM for individual health facilities and the district and state/region as a whole. The results are compared to international standards (see Table 24 from the Sphere Standards). Table 24. Cutoffs for CMAM Outcome Indicators as per Sphere Standards CMAMOutpatient care siteInpatient care siteCure rate> 75 %> 75 %> 75 %*Default rate< 15 %< 15 %< 15 %*Death rate< 10 %--Coverage> 50% in rural areas, >70 % in urban areas and >90% in camp situations*Only if treatment until full recovery The information will help service planners determine if: Services are reaching the target population Sites are performing well Overall district and state/region services are performing well Changes in strategy are needed or are having an effect Supply and human resources need adaptation In the initial phase of CMAM implementation, it is recommended to maintain a standardised and comprehensive M&R system. The disaggregated monthly site reports and aggregated monthly state/region and national reports provide the key outcome indicators for M&R effectiveness of CMAM services (see Section 7.2 for indicators). Additional information can be added depending on available capacity. More substantive reporting is indicated during periodical reviews. The narrative report developed based on the minimum reporting guidance will enhance standardised reporting. The quantitative information from the monthly reports will be interpreted together with qualitative information derived from various sources, such as from stakeholder group discussions, interviews, supervisory checklists and observations. Then this information is triangulated and will strengthen the interpretation of the findings. The comprehensive information enables health managers, health care providers and outreach workers, in collaboration with supervisors and the communities, to strengthen the quality of services for CMAM. (See Annex 34. Minimal Reporting Guidance for CMAM.) Roles and responsibilities for the management of CMAM M&R should be defined among staff at the community outreach, inpatient care or outpatient care sites and also at the district and state/region MOH levels. These roles should be integrated in the job descriptions (see Annex 40. Staff Needs, and Roles and Job Descriptions). Examples of the roles and responsibilities of CMAM information focal persons include: Fill tally sheets Complete monthly statistical and community outreach reports Assess secondary contextual information Complete monthly or periodic narrative reports Analyse and discuss report results and provide feedback Forward reports to higher level Control quality of information Train on CMAM M&R system Provide support and supervision for quality improvement Advocate for and ensure actions based on findings Update and maintain database and repository Indicators collected from inpatient and outpatient care need to be continuously and systematically reviewed to ensure quality information is collected. Quality checks should be conducted to identify whether indicator levels have fallen below the established standards. A level of action should be determined based on the context, the specific indicator that is faltering and whether aggravating factors were present. Minimum standards should not be taken as absolute, but as flexible levels for warning that vary depending on the aforementioned factors, and must be established as such (see Table 24). List of Annexes Community Outreach JOB AIDS 1. Community Outreach Messages Outpatient and Inpatient Care JOB AIDS 2. Admission and Discharge Criteria to CMAM for Children Under 5 3. HYPERLINK \l "_Toc206819306"Anthropometric Measurements 4. Anthropometry Look-Up Tables 5. Guidance Table to Identify Target Weight for Discharge 6. Routine Medicines Protocols 7. Supplementary Medicines Protocols 8. Drug Doses 9. Sugar Water Protocol 10. Appetite Test 11. Dietary Treatment 12. Therapeutic Feeds Look-Up Tables 13. Danger Signs for Inpatient Care 14. HYPERLINK \l "_Toc206819336"Alternative Recipes for F75, F100 and ReSoMal Using CMV 15. Use of Home-Modified Cow Milk for Replacement Feeding in Case of No Access to Infant Formula 16. RUTF Specifications 17. Action Protocol in Outpatient Care 18. Key Messages Upon Admission to Outpatient Care 19. Health and Nutrition Education Messages 20. Emotional and Physical Stimulation 21. Failure to Respond to Treatment in Inpatient Care Monitoring and Reporting Tools 22. Community Assessment Questionnaire and Tools 23. Referral Slip Community Screening 24. Home Visit Record Form 25. Checklist for Home Visits 26. Community Outreach Reporting Sheet 27. HYPERLINK \l "_Toc206819323"Inpatient Care Treatment Card  28. Daily Feeds Chart 29. HYPERLINK \l "_Toc206819323"Outpatient Care Treatment Card  30. RHYPERLINK \l "_Toc206819331"eferral Form for Inpatient Care/Outpatient Care 31. HYPERLINK \l "_Toc206819339"Site Tally Sheet 32. HYPERLINK \l "_Toc206819340"Site Reporting Sheet 33. Monthly District and HYPERLINK \l "_Toc206819341"State/Region Reporting Sheet 34. Minimal Reporting Guidance for CMAM 35. HYPERLINK \l "_Toc206819305"Checklists for Supportive Supervision Management Tools 36. Set-up of Inpatient Care and Outpatient Care 37. HYPERLINK \l "_Toc206819305"Checklist of Materials for Inpatient Care 38. HYPERLINK \l "_Toc206819305"Checklist of Materials for Outpatient Care 39. HYPERLINK \l "_Toc206819338"Forecasting Nutrition Product Needs 40. Staff Needs, and Roles and Responsibilities 41. List of Job Aids Appendix Clinical Management of SAM with Medical Complications in Inpatient Care  REFERENCES can be found following the Appendix. Annex 1. Community Outreach Messages (Examples from Ghana) To community-based organisations Dear Sir/Madam: Re: New treatment for children with severe acute malnutrition A new treatment is now available at Swedru hospital, Kwanyako, Abodom, Duakwa and Nsaba health centres under Agona Locality Health Directorate for children who are very thin or swollen (signs of severe acute malnutrition, or SAM). These children need referral to the health centre where they will receive an assessment. If a child with SAM has a good appetite and no medical complication, the child does not have to go to the hospital. S/he is given medicines and a weekly supply of the nutritional food called Plumpynut and followed up through weekly health centre visits. If a child with SAM has poor appetite or has a medical complication, then s/he will be admitted to the hospital for a short time until the complication is resolving and then will receive further treatment at the health centre and at home. Children under 6 months who are very thin or swollen will need specialised care in Swedru hospital. To determine whether a child is eligible for this treatment, his/her arm is measured in the community to see if s/he is too thin and both feet are checked for swelling. The arm measurement is taken with a tape similar to the cloth tape tailors use in the marketplace and can be taken by many types of persons. Community health workers or volunteers are being trained in communities around the above-mentioned health facilities to take the measurement so that it can be taken by a person the child or his/her family knows. If you know a child who is very thin or whose feet are swollen, tell the parents or guardians about this new treatment. They can ask around their neighbourhood for a community health worker or volunteer or someone else trained to take the arm measurement, or they can go directly to these health facilities. We are confident that this new treatment will significantly improve the Localitys ability to support the recovery of malnourished children, and we look forward to your cooperation. Please do not hesitate to contact me for more information or clarification. Yours faithfully, Director of Health To health facilities Dear Sir/Madam: Re: Community-Based Management of Acute Malnutrition As part of its mandate to improve the quality and accessibility of health services in Agona Locality, the Ghana Health Services (GHS) has introduced a new treatment for children under 5 years who have a severe form of acute malnutrition (bilateral pitting oedema or severe wasting). The service is called Community-Based Management of Acute Malnutrition (CMAM). It brings the treatment of children with severe acute malnutrition (SAM) much closer to the family, making it possible for children and their mothers/caregivers to avoid the long stays at the Pediatric Ward or the Nutrition Rehabilitation Centre that customarily have been necessary for treating undernutrition. Children in the communities and the health facilities are checked for bilateral pitting oedema and screened for severe wasting based on a mid-upper arm circumference (MUAC) measurement with a specially marked tape (MUAC tape) for referral and admission to the CMAM service at the health centre. At the health facility the child with SAM receives a medical evaluation. If a child with SAM has a good appetite and no medical complications, s/he can be treated at home and followed up through weekly health centre visits. If a child with SAM has poor appetite or has a medical complication, then s/he will be admitted to inpatient care at Swedru Hospital for a short time until the medical complication is resolving and then receive further treatment at the health centre and at home. Children under 6 months who are very thin or have swelling will need specialised care in inpatient care at Swedru hospital. Early detection of cases and referral for treatment is essential to avoid medical complications. The treatment, which is free of charge, provides antibiotic, antihelminthic and malaria drug treatment; vitamin A supplementation; and a ready-to-use therapeutic food (RUTF) called Plumpynut that the families of eligible children can take home from the health facility. We would like to involve a variety of health practitioners and service providers, including private clinics, to help us identify children with SAM so they can be treated at an early stage. Currently the services are provided in five sites (Swedru Hospital and Kwanyako, Abodom, Duakwa and Nsaba Health Centres) under Agona Locality Health Directorate, but it is hoped that the services will be extended to other health centres in Agona Locality. Therefore, we kindly request that your health facility brief all staff members, especially those in the outpatient department, and have them refer children with bilateral pitting oedema and severe wasting to any of the above-mentioned health centres for treatment. The GHS SAM team would be pleased to provide your clinic with MUAC tapes and train your staff in identifying and treating children with bilateral pitting oedema and severe wasting. We are confident that the CMAM services will significantly improve the Localitys ability to support the recovery of malnourished children, and we look forward to your cooperation. Please do not hesitate to contact us for more information or clarification. Yours faithfully, Director of Health To mothers/caregivers with children 6-59 months A new treatment is now available for children under 5 years with severe acute malnutrition (SAM). These children are very thin or are swollen and need a specific treatment with medicines and a nutritional food that will be provided at the health centre after a medical check. If a child with SAM has a good appetite and no medical complications, s/he can be treated at home and followed up through weekly health centre visits. These children do not have to go to the hospital but can stay at home with their families. If the child with SAM has poor appetite or has developed a medical complication, then s/he will be admitted to the hospital for a short time until the complication is resolving. The child will continue treatment at the health facility and at home. Children under 6 months who are very thin or are swollen will need specialised care in inpatient care in Swedru Hospital. How to know whether your child needs this treatment Some people within your communities have been trained to take an arm measurement of children with a small tape and check whether both feet are swollen. The treatment All children found to be thin or swollen are referred to the health centre, where the arm measurement and swelling are checked again. If the children have an appetite and are clinically well, they are given medicines and a weekly supply of the nutritional food called Plumpynut. Only the children who are very small or very ill will need referral to inpatient care. If you know a child who appears to be very thin or whose feet are swollen, tell his/her parents or guardians about this new treatment. They can ask around their neighbourhood for a community health worker, volunteer, or someone else trained to take the arm measurement. Or, they can go directly to the health centres to have their child measured any day. Follow-up service days in the health centres are: Swedru Hospital on Monday Kwanyako Health Centre on Wednesday Abodom Health Centre on Wednesday Nsaba Health Centre on Friday Duakwa Health Centre on Friday Annex 2. Admission and Discharge Criteria to CMAM for Children Under 5 Inpatient Care  Outpatient Care ADMISSION CRITERIA CHILDREN 6-59 MONTHS  FORMCHECKBOX  Bilateral pitting oedema +++  CHILDREN 6-59 MONTHS  FORMCHECKBOX  Bilateral pitting oedema + and ++ OR  FORMCHECKBOX  Any grade of bilateral pitting oedema with severe wasting OR  FORMCHECKBOX  Severe wasting (MUAC < 115 mm or WFH < -3 z-score) AND Appetite test passed No medical complication Child clinically well and alert OR  FORMCHECKBOX  SAM with any of the following medical complications:Anorexia, poor appetite Intractable vomiting Convulsions Lethargy, not alert Unconsciousness Hypoglycaemia High fever Hypothermia Severe dehydration Persistent diarrhoea Lower respiratory tract infection Severe anaemia Eye signs of vitamin A deficiency Skin lesion OR  FORMCHECKBOX  Referred from outpatient care according to action protocol INFANTS < 6 MONTHS  FORMCHECKBOX  Bilateral pitting oedema OR  FORMCHECKBOX  Visible wasting - Includes infants with SAM e" 6 months and < 4 kg REFERRAL/DISCHARGE CRITERIA CHILDREN 6-59 MONTHS  FORMCHECKBOX  Referred to outpatient care: Appetite returned (passed appetite test) Medical complication resolving Severe bilateral pitting oedema decreasing Child clinically well and alert (If admitted due to bilateral pitting oedema and severe wasting: criterion for referral is bilateral pitting oedema resolved)  FORMCHECKBOX  Discharged cured (special cases): 15 percent weight gain maintained for two consecutive days Oedema free for two consecutive weeks Child clinically well and alert INFANTS < 6 MONTHS  FORMCHECKBOX  Discharged cured: If successful re-lactation and appropriate weight gain maintained (minimum 20 g per day on breastfeeding alone for five days) and infant clinically well and alert (if infant has no access to breastfeeding, see other guidance for non-breastfed children on replacement feeding)  CHILDREN 6-59 MONTHS  FORMCHECKBOX  Discharged cured: 15 percent weight gain maintained for two consecutive visits (of admission weight or weight free of oedema) Oedema free for two consecutive visits Child clinically well and alert Children are referred to receive supplementary feeding if available Annex 3. Anthropometric Measurements BILATERAL PITTING OEDEMA Bilateral pitting oedema, or kwashiorkor, can be verified when thumb pressure applied on top of both feet for three seconds leaves a pit (indentation) in the foot after the thumb is lifted. The pit will remain in both feet for several seconds. Bilateral pitting oedema usually starts in the feet and ankles. It is important to test both feet; if the pitting is not bilateral, the oedema is not of nutritional origin. A second person repeats the test to confirm the presence of bilateral pitting oedema. There are three grades of bilateral pitting oedema. When there is no bilateral pitting oedema, the grade is absent. Grades of bilateral pitting oedema are classified by plus signs. Grades of Bilateral Pitting Oedema Grade DefinitionAbsent or 0No bilateral pitting oedemaGrade +Mild: Both feet/anklesGrade ++Moderate: Both feet, plus lower legs, hands or lower armsGrade +++Severe: Generalised bilateral pitting oedema, including both feet, legs, arms and face Pictures of Bilateral Pitting Oedema Grade + In this child, there is bilateral pitting oedema in both feet. This is grade + oedema (mild), however the child might have grade ++ or +++, so legs and face will also need to be checked. Grade ++ In this child, both feet plus the lower legs, hands and lower arms are swollen. This is grade + + bilateral pitting oedema (moderate). Grade +++ This child has +++ bilateral pitting oedema (severe). It is generalised, including both feet, legs, arms, hands and face. MID-UPPER ARM CIRCUMFERENCE OR MUAC MUAC is used for children 6-59 months. It is essential to use the age cutoff of 6 months for MUAC. It is not recommended to use a height cutoff as proxy for 6 months of age; in a stunted population many infants 6 months or older will have a height less than 65 centimetres (cm). If the birth date is unconfirmed, use the recall of the mother/caregiver to estimate the infants age. How to measure MUAC: MUAC is always taken on the left arm. Measure the length of the childs upper arm, between the bone at the top of the shoulder and the tip of the elbow (the childs arm should be bent). Find the midpoint of the upper arm and mark it with a pen. It is recommended to use a string instead of the MUAC tape to find the midpoint. The childs arm should then be relaxed, falling alongside his/her body. Wrap the MUAC tape around the childs arm, such that all of it is in contact with the childs skin. It should be neither too tight nor too loose. For the numbered tapes, feed the end of the tape down through the first opening and up through the third opening. The measurement is read from the middle window where the arrows point inward. MUAC can be recorded with a precision of 1 millimetre (mm). For the simple three-color tape (red, yellow, green), slide the end through the first opening and then through the second opening. Read the colour that shows through the window at the point the two arrows indicate.  WEIGHT To increase accuracy and precision, two people are always needed to measure weight. Weight can be measured using a Salter-type hanging spring scale (as is commonly found in the field) or an electronic scale such as the United Nations Childrens Fund (UNICEF) UNISCALE, which is more precise and allows a child to be measured in the mother/caregivers arms. Hanging Spring (Salter) Scale A 25 kilogram (kg) hanging spring scale, graduated by 0.100 kg, is most commonly used. In the field setting, the scale is hooked to a tree, a tripod or a stick held by two people.In a clinic, it is attached to the ceiling or a stand. Weighing pants (or a weighing hammock for smaller infants) are attached to the scale. Culturally adapted solutions, such as a mothers wrap, basin or grass basket, might be preferable to use to weigh the child. The weighing pants or hammock is suspended from the lower hook of the scale, and the scale is readjusted to zero. The child's clothes are removed and the child is placed in the weighing pants/hammock. The scale should be read at eye level. How to use the Salter Scale: Before weighing the child, take all his/her clothes off. Zero the weighing scales (i.e., make sure the arrow is on 0). Place the child in the weighing pants/hammock, making sure the child is touching nothing. Read the childs weight. The arrow must be steady and the weight/scale should be read at eye level. Record the weight in kg and to the nearest 100 grams (g) (e.g., 6.4 kg). Considerations: Make sure the child is safely in the weighing pants or hammock with one arm in front and one arm behind the straps to help maintain balance. In cold climates or in certain cultures, it might be impossible or impractical to undress a child completely. The average weight of the clothes should be estimated and deducted from the measure. It is helpful to retain similar clothing for girls and boys during weighing to help to standardise weight deductions. When the child is steady and settled, the weight is recorded in kg to the nearest 100 g.If the child is moving and the needle does not stabilise, the weight should be estimated by recording the value at the midpoint of the range of oscillations. The measurer reads the value on the scale aloud, and the assistant repeats it for verification and records it on the treatment card.The child is then dressed. The scale should be checked daily against a known weight. To do this, set the scale to zero and weigh objects of known weight (e.g., 5.0 kg, 10.0 kg, 15.0 kg). If the measure does not match the weight to within 10 grams, the springs must be changed or the scale should be replaced. Weighing an Infant Using a Hanging Spring (Salter) Scale:  SHAPE \* MERGEFORMAT  Weighing an Infant Using an Electronic Scale for Tared Weighing Tared weighing means that the scale can be re-set to zero (tared) with the person just weighed still on it. Explain the tared weighing procedure to the mother as follows. Stress that the mother must stay on the scale until her child has been weighed in her arms. Be sure that the scale is placed on a flat, hard, even surface. Since the scale is solar powered, there must be enough light to operate the scale.   Mother's weight alone. Taring the scale . Baby's weight appears on display.  To turn on the scale, cover the solar panel for a second. When the number 0.0 appears, the scale is ready. Check to see that the mother has removed her shoes. You or someone else should hold the naked baby wrapped in a blanket. Ask the mother to stand in the middle of the scale, feet slightly apart (on the footprints, if marked), and remain still. The mothers clothing must not cover the display or solar panel. Remind the mother to stay on the scale even after her weight appears, until the baby has been weighed in her arms. With the mother still on the scale and her weight displayed, tare the scale by covering the solar panel for a second. The scale is tared when it displays a figure of a mother and baby and the number 0.0. Gently hand the naked baby to the mother and ask her to remain still. The babys weight will appear on the display. Record the weight. Be careful to read the numbers in the correct order (as though you were viewing while standing on the scale rather than standing in front of the scale). If the child is 2 years or older, you will weigh the child alone if the child will stand still. HEIGHT To increase accuracy and precision, two people are always needed to measure length and height. Children aged 2 years or older are measured standing up, while those under 2 are measured lying down. If the age is difficult to assess, children at least 87 cm tall (World Health Organisation [WHO] standards) are measured standing, and those less than 87 cm are measured lying down.If children age 2 or older or at least 87 cm tall are measured lying down, 0.7 cm is subtracted from the measurement. For Children 2 Years or Older or with a Height of 87 cm or Greater The child's shoes are removed. The child is placed on the height board, standing upright in the middle of the board with arms at his/her sides. The assistant firmly presses the child's ankles and knees against the board while the measurer holds the childs head straight. The child's head, shoulders, buttocks and heels should be touching the board, and his/her feet should be close together. The measurer positions the sliding board and takes the measurement to the nearest 0.1 cm. The measurer announces the measurement, and the assistant repeats it for verification and records it on the anthropometric form or health card.  For Children under 2 Years or under 87 cm Tall The height board is placed on the ground. The childs shoes are removed. The child is gently placed on his/her back on the middle of the board, facing straight up with arms at his/her sides and feet at right angles. The assistant holds the sides of the child's head and positions it on the board. While holding down the child's ankles or knees, the measurer moves the sliding board up against the bottom of the child's feet and takes the measurement to the nearest 0.1 cm. The measurer announces the measurement, and the assistant repeats it for verification and records it on the anthropometric form or health card.  BODY MASS INDEX (BMI) BMI or Quetelets index is based on a weight-to-height ratio that is considered a good index of body fat and protein stores. Body stores are of interest because they reflect the stores needed to cope with physiological stress due to reduced intake and increased demands due to increased activity, pregnancy and diseases. Adults who have a healthy nutritional status would be expected to have body stores or BMI within a certain range. The formula for BMI is the weight (in kg) divided by the height (in meters [m]) squared: BMI = weight / (height) 2 Example: A man who weighs 55.5 kg with a height of 162.5 cm would have a BMI of (55.5/(1.625x1.625)) = 20.9. When an adult is too ill to stand or has a spinal deformity, the half-arm span should be measured to estimate the height. This is the distance from the middle of the sternal notch to the tip of the middle finger with the arm held out horizontally to the side. Both sides should be measured. If there is a discrepancy, the measurements should be repeated and the longest one taken. The BMI is then computed from the calculated height and measured weight. The height (in m) can then be calculated as follows: Height = [0.73 x (2 x half arm span))] ++0.43 The WHO classification of malnutrition in adults by BMI is as follows: Nutritional Status BMI (kg/m2) Normal e" 18.5 Mild malnutrition 17.0  18.49 Moderate malnutrition 16.0  16.99 Severe malnutrition < 16.0 While these categories are suggested, there is difficulty in using them to compare across populations due to 1) a lack of understanding of the functional significance of these categories and 2) the influence of body shape to interpreting BMI. The BMI look-up table is found in Annex 4. Anthropometry Look-Up Tables.  BMI-for-Age The release of the WHO 2006 child growth standards (WHO Standards) prompted the development of the WHO 2007 growth reference for school-aged children and adolescents 5-19 years (WHO Reference). The new reference indicator for wasting for school-aged children and adolescents 5-19 years is BMI-for-age (WHO Reference) and replaces the WHO previously recommended weight-for-height (WFH; National Centre for Health Statistics [NCHS] Reference) as indicator for wasting for children over 5 years. (The BMI-for-age [NCHS Reference] tables started at 9 years only).   The BMI-for-age indicator for severe wasting is expressed in a z-score below 3 standard deviations (SD) of the median and for moderate wasting below 2 SD of the median (WHO Reference). The BMI and BMI-for-age look-up tables for boys and girls are found in Annex 4. Anthropometry Look-Up Tables. Annex 4. Anthropometry Look-Up Tables Weight-for-Length Look-Up Table, Children 6-23 Months, WHO 2006 Child Growth Standards Boys' Weight (kg)Length aGirls' Weight (kg)-3 SD-2 SD-1 SDMedian(cm)Median-1 SD-2 SD-3 SD1.92.02.22.4452.52.32.11.92.02.22.42.6462.62.42.22.02.12.32.52.8472.82.62.42.22.32.52.72.9483.02.72.52.32.42.62.93.1493.22.92.62.42.62.83.03.3503.43.12.82.62.73.03.23.5513.63.33.02.82.93.23.53.8523.83.53.22.93.13.43.74.0534.03.73.43.13.33.63.94.3544.33.93.63.33.63.84.24.5554.54.23.83.53.84.14.44.8564.84.44.03.74.04.34.75.1575.14.64.33.94.34.65.05.4585.44.94.54.14.54.85.35.7595.65.14.74.34.75.15.56.0605.95.44.94.54.95.35.86.3616.15.65.14.75.15.66.06.5626.45.85.34.95.35.86.26.8636.66.05.55.15.56.06.57.0646.96.35.75.35.76.26.77.3657.16.55.95.55.96.46.97.5667.36.76.15.66.16.67.17.7677.56.96.35.86.36.87.38.0687.77.16.56.06.57.07.68.2698.07.36.76.16.67.27.88.4708.27.56.96.36.87.48.08.6718.47.77.06.57.07.68.28.9728.67.87.26.67.27.78.49.1738.88.07.46.87.37.98.69.3749.08.27.56.97.58.18.89.5759.18.47.77.17.68.38.99.7769.38.57.87.27.88.49.19.9779.58.78.07.47.98.69.310.1789.78.98.27.58.18.79.510.3799.99.18.37.78.28.99.610.48010.19.28.57.88.49.19.810.68110.39.48.78.08.59.210.010.88210.59.68.88.18.79.410.211.08310.79.89.08.38.99.610.411.38411.010.19.28.59.19.810.611.58511.210.39.48.79.310.010.811.78611.510.59.78.99.510.211.112.08711.710.79.99.19.710.511.312.28812.011.010.19.39.910.711.512.58912.211.210.39.510.110.911.812.79012.511.410.59.710.311.112.013.09112.711.710.79.910.511.312.213.29213.011.910.910.110.711.512.413.49313.212.111.110.210.811.712.613.79413.512.311.310.411.011.912.813.99513.712.611.510.611.212.113.114.19614.012.811.710.811.412.313.314.49714.213.012.011.011.612.513.514.69814.513.312.211.211.812.713.714.99914.813.512.411.412.012.914.015.210015.013.712.611.6a Length is measured for children under 2 years or less than 87 cm height. For children 2 years or older or 87 cm height or greater, height is measured. Recumbent length is, on average, 0.7 cm greater than standing height; although the difference is of no importance to individual children, a correction may be made by subtracting 0.7 cm from all lengths above 86.9 cm if standing height cannot be measured. Weight-for-Height Look-Up Table, Children 24-59 Months, WHO 2006 Child Growth Standards Boys' Weight (kg)Height aGirls' Weight (kg)-3 SD-2 SD-1 SDMedian(cm)Median-1 SD-2 SD-3 SD5.96.36.97.4657.26.66.15.66.16.57.17.7667.56.86.35.86.26.77.37.9677.77.06.45.96.46.97.58.1687.97.26.66.16.67.17.78.4698.17.46.86.36.87.37.98.6708.37.67.06.46.97.58.18.8718.57.87.16.67.17.78.39.0728.78.07.36.77.37.98.59.2738.98.17.56.97.48.08.79.4749.18.37.67.07.68.28.99.6759.38.57.87.27.78.49.19.8769.58.78.07.37.98.59.210.0779.68.88.17.58.08.79.410.2789.89.08.37.68.28.89.610.47910.09.28.47.88.39.09.710.68010.29.48.67.98.59.29.910.88110.49.68.88.18.79.310.111.08210.79.89.08.38.89.510.311.28310.910.09.28.59.09.710.511.48411.110.29.48.69.210.010.811.78511.410.49.68.89.410.211.011.98611.610.79.89.09.610.411.212.28711.910.910.09.29.810.611.512.48812.111.110.29.410.010.811.712.68912.411.410.49.610.211.011.912.99012.611.610.69.810.411.212.113.19112.911.810.910.010.611.412.313.49213.112.011.110.210.811.612.613.69313.412.311.310.411.011.812.813.89413.612.511.510.611.112.013.014.19513.912.711.710.811.312.213.214.39614.112.911.910.911.512.413.414.69714.413.212.111.111.712.613.714.89814.713.412.311.311.912.913.915.19914.913.712.511.512.113.114.215.410015.213.912.811.712.313.314.415.610115.514.213.012.012.513.614.715.910215.814.513.312.212.813.814.916.210316.114.713.512.413.014.015.216.510416.415.013.812.613.214.315.516.810516.815.314.012.913.414.515.817.210617.115.614.313.113.714.816.117.510717.515.914.613.413.915.116.417.810817.816.314.913.714.115.316.718.210918.216.615.213.914.415.617.018.511018.617.015.514.214.615.917.318.911119.017.315.814.514.916.217.619.211219.417.716.214.815.216.518.019.611319.818.016.515.115.416.818.320.011420.218.416.815.415.717.118.620.411520.718.817.215.716.017.419.020.811621.119.217.516.016.217.719.321.211721.519.617.816.316.518.019.721.611822.019.918.216.616.818.320.022.011922.420.318.516.917.118.620.422.412022.820.718.917.3a Length is measured for children under 2 years or less than 87 cm height. For children 2 years or older or 87 cm height or more, height is measured. Recumbent length is, on average, 0.7 cm greater than standing height; although the difference is of no importance to individual children, a correction may be made by subtracting 0.7 cm from all lengths greater than 86.9 cm if standing height cannot be measured. BMI Look-Up Tables 1011121314151617181920212223242526272829303132333435363738959.09.910.811.712.613.514.415.316.217.118.119.019.920.821.722.623.524.425.326.227.128.028.929.830.731.632.533.434.395969.210.111.112.012.913.814.715.716.617.518.419.420.321.222.123.024.024.925.826.727.628.629.530.431.332.333.234.135.096979.410.311.312.213.214.115.116.016.917.918.819.820.721.622.623.524.525.426.327.328.229.230.131.032.032.933.934.835.897989.610.611.512.513.414.415.416.317.318.219.220.221.122.123.024.025.025.926.927.928.829.830.731.732.733.634.635.536.598999.810.811.812.713.714.715.716.717.618.619.620.621.622.523.524.525.526.527.428.429.430.431.432.333.334.335.336.337.29910010.011.012.013.014.015.016.017.018.019.020.021.022.023.024.025.026.027.028.029.030.031.032.033.034.035.036.037.038.010010110.211.212.213.314.315.316.317.318.419.420.421.422.423.524.525.526.527.528.629.630.631.632.633.734.735.736.737.738.810110210.411.412.513.514.615.616.617.718.719.820.821.822.923.925.026.027.128.129.130.231.232.333.334.335.436.437.538.539.510210310.611.712.713.814.915.917.018.019.120.221.222.323.324.425.526.527.628.629.730.831.832.933.935.036.137.138.239.340.310310410.811.913.014.115.116.217.318.419.520.621.622.723.824.926.027.028.129.230.331.432.433.534.635.736.837.938.940.041.110410511.012.113.214.315.416.517.618.719.820.922.123.224.325.426.527.628.729.830.932.033.134.235.336.437.538.639.740.841.910510611.212.413.514.615.716.918.019.120.221.322.523.624.725.827.028.129.230.331.532.633.734.836.037.138.239.340.441.642.710610711.412.613.714.916.017.218.319.520.621.822.924.025.226.327.528.629.830.932.133.234.335.536.637.838.940.141.242.443.510710811.712.814.015.216.317.518.719.821.022.223.324.525.726.828.029.230.331.532.733.835.036.237.338.539.740.842.043.244.310810911.913.114.315.416.617.819.020.221.422.623.825.026.127.328.529.730.932.133.334.535.636.838.039.240.441.642.844.045.110911012.113.314.515.716.918.219.420.621.823.024.225.426.627.829.030.331.532.733.935.136.337.538.739.941.142.443.644.846.011011112.313.614.816.017.218.519.720.922.223.424.625.927.128.329.630.832.033.334.535.737.038.239.440.741.943.144.445.646.811111212.513.815.116.317.618.820.121.322.623.825.126.327.628.930.131.432.633.935.136.437.638.940.141.442.643.945.246.447.711211312.814.015.316.617.919.220.421.723.024.325.526.828.129.430.631.933.234.535.837.038.339.640.942.143.444.746.047.248.511311413.014.315.616.918.219.520.822.123.424.726.027.328.629.931.232.533.835.136.437.739.040.341.642.944.245.546.848.149.411411513.214.515.917.218.519.821.222.523.825.126.427.829.130.431.733.134.435.737.038.439.741.042.343.645.046.347.648.950.311511613.514.816.117.518.820.221.522.924.225.626.928.329.630.932.333.635.036.337.739.040.441.743.144.445.847.148.449.851.111611713.715.116.417.819.220.521.923.324.626.027.428.730.131.532.934.235.637.038.339.741.142.443.845.246.547.949.350.652.011711813.915.316.718.119.520.922.323.725.126.527.829.230.632.033.434.836.237.639.040.441.843.244.645.947.348.750.151.552.911811914.215.617.018.419.821.222.724.125.526.928.329.731.232.634.035.436.838.239.741.142.543.945.346.748.149.651.052.453.811912014.415.817.318.720.221.623.024.525.927.428.830.231.733.134.636.037.438.940.341.843.244.646.147.549.050.451.853.354.712012114.616.117.619.020.522.023.424.926.427.829.330.732.233.735.136.638.139.541.042.543.945.446.948.349.851.252.754.255.612112214.916.417.919.320.822.323.825.326.828.329.831.332.734.235.737.238.740.241.743.244.746.147.649.150.652.153.655.156.612212315.116.618.219.721.222.724.225.727.228.730.331.833.334.836.337.839.340.842.443.945.446.948.449.951.453.054.556.057.512312415.416.918.520.021.523.124.626.127.729.230.832.333.835.436.938.440.041.543.144.646.147.749.250.752.353.855.456.958.412412515.617.218.820.321.923.425.026.628.129.731.332.834.435.937.539.140.642.243.845.346.948.450.051.653.154.756.357.859.412512615.917.519.120.622.223.825.427.028.630.231.833.334.936.538.139.741.342.944.546.047.649.250.852.454.055.657.258.760.312612716.117.719.421.022.624.225.827.429.030.632.333.935.537.138.740.341.943.545.246.848.450.051.653.254.856.558.159.761.312712816.418.019.721.322.924.626.227.929.531.132.834.436.037.739.341.042.644.245.947.549.250.852.454.155.757.359.060.662.312812916.618.320.021.623.325.026.628.330.031.633.334.936.638.339.941.643.344.946.648.349.951.653.354.956.658.259.961.663.212913016.918.620.322.023.725.427.028.730.432.133.835.537.238.940.642.343.945.647.349.050.752.454.155.857.559.260.862.564.213013117.218.920.622.324.025.727.529.230.932.634.336.037.839.541.242.944.646.348.149.851.553.254.956.658.360.161.863.565.213113217.419.220.922.724.426.127.929.631.433.134.836.638.340.141.843.645.347.048.850.552.354.055.857.559.261.062.764.566.213213317.719.521.223.024.826.528.330.131.833.635.437.138.940.742.544.246.047.849.551.353.154.856.658.460.161.963.765.467.213313418.019.821.523.325.126.928.730.532.334.135.937.739.541.343.144.946.748.550.352.153.955.757.559.361.162.864.666.468.213413518.220.021.923.725.527.329.231.032.834.636.538.340.141.943.745.647.449.251.052.954.756.558.360.162.063.865.667.469.313513618.520.322.224.025.927.729.631.433.335.137.038.840.742.544.446.248.149.951.853.655.557.359.261.062.964.766.668.470.313613718.820.622.524.426.328.230.031.933.835.737.539.441.343.245.046.948.850.752.654.456.358.260.161.963.865.767.669.471.313713819.020.922.924.826.728.630.532.434.336.238.140.041.943.845.747.649.551.453.355.257.159.060.962.864.766.768.670.572.413813919.321.323.225.127.029.030.932.834.836.738.640.642.544.446.448.350.252.254.156.058.059.961.863.865.767.669.671.573.413914019.621.623.525.527.429.431.433.335.337.239.241.243.145.147.049.051.052.954.956.858.860.862.764.766.668.670.672.574.514014119.921.923.925.827.829.831.833.835.837.839.841.843.745.747.749.751.753.755.757.759.661.663.665.667.669.671.673.675.514114220.222.224.226.228.230.232.334.336.338.340.342.344.446.448.450.452.454.456.558.560.562.564.566.568.670.672.674.676.614214320.422.524.526.628.630.732.734.836.838.940.942.945.047.049.151.153.255.257.359.361.363.465.467.569.571.673.675.777.714314420.722.824.927.029.031.133.235.337.339.441.543.545.647.749.851.853.956.058.160.162.264.366.468.470.572.674.676.778.814414521.023.125.227.329.431.533.635.737.839.942.144.246.348.450.552.654.756.858.961.063.165.267.369.471.573.675.777.879.914514621.323.425.627.729.832.034.136.238.440.542.644.846.949.051.253.355.457.659.761.863.966.168.270.372.574.676.778.981.014614721.623.825.928.130.332.434.636.738.941.143.245.447.549.751.954.056.258.360.562.764.867.069.171.373.575.677.880.082.11471011121314151617181920212223242526272829303132333435363738 BMI Look-Up Tables (continued) 101112131415161718192021222324252627282930313233343536373814821.924.126.328.530.732.935.037.239.441.643.846.048.250.452.654.857.059.161.363.565.767.970.172.374.576.778.981.083.214814922.224.426.628.931.133.335.537.740.042.244.446.648.851.153.355.557.759.962.264.466.668.871.073.375.577.779.982.184.414915022.524.827.029.331.533.836.038.340.542.845.047.349.551.854.056.358.560.863.065.367.569.872.074.376.578.881.083.385.515015122.825.127.429.631.934.236.538.841.043.345.647.950.252.454.757.059.361.663.866.168.470.773.075.277.579.882.184.486.615115223.125.427.730.032.334.737.039.341.643.946.248.550.853.155.457.860.162.464.767.069.371.673.976.278.680.983.285.587.815215323.425.728.130.432.835.137.539.842.144.546.849.251.553.856.258.560.963.265.567.970.272.674.977.279.681.984.386.689.015315423.726.128.530.833.235.637.940.342.745.147.449.852.254.556.959.361.764.066.468.871.173.575.978.380.683.085.487.790.115415524.026.428.831.233.636.038.440.843.245.648.150.552.956.357.760.162.564.967.369.772.174.576.979.381.784.186.588.991.315515624.326.829.231.634.136.538.941.443.846.248.751.153.556.058.460.863.365.768.170.673.075.477.980.382.785.287.690.092.515615724.627.129.632.034.537.039.441.944.446.849.351.854.256.759.261.664.166.669.071.573.976.478.981.383.886.388.791.293.715715825.027.530.032.534.937.439.942.444.947.449.952.454.957.459.962.464.967.469.972.474.977.479.982.484.987.489.992.494.915815925.327.830.332.935.437.940.443.045.548.050.653.155.658.160.763.265.768.370.873.375.878.480.983.486.088.591.093.596.115916025.628.230.733.335.838.441.043.546.148.651.253.856.358.961.464.066.669.171.774.276.879.481.984.587.089.692.294.797.316016125.928.531.133.736.338.941.544.146.749.251.854.457.059.662.264.867.470.072.675.277.880.482.985.588.190.793.395.998.516116226.228.931.534.136.739.442.044.647.249.952.555.157.760.463.065.668.270.973.576.178.781.484.086.689.291.994.597.199.716216326.629.231.934.537.239.942.545.247.850.553.155.858.561.163.866.469.171.774.477.179.782.485.087.790.393.095.698.310116316426.929.632.335.037.740.343.045.748.451.153.856.559.261.964.667.269.972.675.378.080.783.486.188.891.494.196.899.510216416527.229.932.735.438.140.843.646.349.051.754.557.259.962.665.368.170.873.576.279.081.784.487.189.892.695.398.010110416516627.630.333.135.838.641.344.146.849.652.455.157.960.663.466.168.971.674.477.279.982.785.488.290.993.796.499.210210516616727.930.733.536.339.041.844.647.450.253.055.858.661.464.166.969.772.575.378.180.983.786.589.292.094.897.610010310616716828.231.033.936.739.542.345.248.050.853.656.459.362.164.967.770.673.476.279.081.884.787.590.393.196.098.810210410716816928.631.434.337.140.042.845.748.651.454.357.160.062.865.768.571.474.377.180.082.885.788.591.494.397.110010310610916917028.931.834.737.640.543.346.249.152.054.957.860.763.666.569.472.275.178.080.983.886.789.692.595.498.310110410711017017129.232.235.138.040.943.946.849.752.655.658.561.464.367.370.273.176.079.081.984.887.790.693.696.599.410210510811117117229.632.535.538.541.444.447.350.353.356.259.262.165.168.071.074.076.979.982.885.888.891.794.797.610110410711011217217329.932.935.938.941.944.947.950.953.956.959.962.965.868.871.874.877.880.883.886.889.892.895.898.810210510811111417317430.333.336.339.442.445.448.451.554.557.560.663.666.669.672.775.778.781.784.887.890.893.996.999.910310610911211517417530.633.736.839.842.945.949.052.155.158.261.364.367.470.473.576.679.682.785.888.891.994.998.010110410711011311617517631.034.137.240.343.446.549.652.755.858.962.065.068.171.274.377.480.583.686.789.892.996.099.110210510811211511817617731.334.537.640.743.947.050.153.356.459.562.765.868.972.175.278.381.584.687.790.994.097.110010310711011311611917717831.734.938.041.244.447.550.753.957.060.263.466.569.772.976.079.282.485.588.791.995.198.210110510811111411712017817932.035.238.441.744.948.151.354.557.760.964.167.370.573.776.980.183.386.589.792.996.199.310310610911211511912217918032.435.638.942.145.448.651.855.158.361.664.868.071.374.577.881.084.287.590.794.097.210010410711011311712012318018132.836.039.342.645.949.152.455.759.062.265.568.872.175.478.681.985.288.591.795.098.310210510811111511812112518118233.136.439.743.146.449.753.056.359.662.966.269.672.976.279.582.886.189.492.796.199.410310610911311611912312618218333.536.840.243.546.950.253.656.960.363.667.070.373.777.080.483.787.190.493.897.110110410711111411712112412718318433.937.240.644.047.450.854.257.660.964.367.771.174.577.981.384.688.091.494.898.210210510811211511912212512918418534.237.641.144.547.951.354.858.261.665.068.571.975.378.782.185.689.092.495.899.310310611011311612012312713018518634.638.141.545.048.451.955.458.862.365.769.272.776.179.683.086.589.993.496.910010410711111411812112512813218618735.038.542.045.549.052.556.059.462.966.469.973.476.980.483.987.490.994.497.910110510811211511912212612913318718835.338.942.445.949.553.056.660.163.667.270.774.277.881.384.888.491.995.499.010310611011311712012412713113418818935.739.342.946.450.053.657.260.764.367.971.475.078.682.285.789.392.996.410010410711111411812212512913213618919036.139.743.346.950.554.257.861.465.068.672.275.879.483.086.690.393.997.510110510811211611912312613013413719019136.540.143.847.451.154.758.462.065.769.373.076.680.383.987.691.294.998.510210610911311712012412813113513919119236.940.644.247.951.655.359.062.766.470.073.777.481.184.888.592.295.899.510310711111411812212512913313614019219337.241.044.748.452.155.959.663.367.070.874.578.281.985.789.493.196.810110410811211611912312713013413814219319437.641.445.248.952.756.560.264.067.771.575.379.082.886.690.394.197.910210510911311712012412813213613914319419538.041.845.649.453.257.060.864.668.472.276.179.983.787.591.395.198.910310711011411812212612913313714114519519638.442.346.149.953.857.661.565.369.173.076.880.784.588.492.296.099.910410811111511912312713113513814214619619738.842.746.650.554.358.262.166.069.973.777.681.585.489.393.197.010110510911311612012412813213614014414819719839.243.147.051.054.958.862.766.670.674.578.482.386.290.294.198.010210611011411812212612913313714114514919819939.643.647.551.555.459.463.467.371.375.279.283.287.191.195.099.010310711111511912312713113513914314715119920040.044.048.052.056.060.064.068.072.076.080.084.088.092.096.01001041081121161201241281321361401441481522001011121314151617181920212223242526272829303132333435363738 BMI-for-Age Look-Up Table School-Aged Children and Adolescents 5-19 Years - WHO 2007 Growth Reference Boys' BMI-for-ageYear: MonthGirls' BMI-for-age-3 SD-2 SD-1 SDMedianMedian-1 SD-2 SD-3 SD12.113.014.115.35:115.213.912.711.812.113.014.115.35:615.213.912.711.712.113.014.115.36:015.313.912.711.712.213.114.115.46:615.313.912.711.712.313.114.215.57:015.413.912.711.812.313.214.315.67:615.514.012.811.812.413.314.415.78:015.714.112.911.912.513.414.515.98:615.914.313.012.012.613.514.616.09:016.114.413.112.112.713.614.816.29:616.314.613.312.212.813.714.916.410:016.614.813.512.412.913.915.116.710:616.915.113.712.513.114.115.316.911:017.215.313.912.713.214.215.517.211:617.615.614.112.913.414.515.817.512:018.016.014.413.213.614.716.117.912:618.416.314.713.413.814.916.418.213:018.816.614.913.614.015.216.718.613:619.216.915.213.814.315.517.019.014:019.617.215.414.014.515.717.319.414:619.917.515.714.214.716.017.619.815:020.217.815.914.414.916.318.020.115:620.518.016.014.515.116.518.220.516:020.718.216.214.615.316.718.520.816:620.918.316.314.715.416.918.821.117:021.018.416.414.715.617.119.021.417:621.218.516.414.715.717.319.221.718:021.318.616.414.715.817.419.422.018:621.318.616.514.715.917.619.622.219:021.418.716.514.7 Annex 5. Guidance Table to Identify Target Weight for Discharge Guidance Table to Identify the Target Weight for Children 6-59 Months Weight on admissiona,bTarget weight: 15% weight gain Weight on admissiona,bTarget weight: 15% weight gain4.14.711.112.84.34.911.313.04.55.211.513.24.75.411.713.54.95.611.913.75.15.912.113.95.36.112.314.15.56.312.514.45.76.612.714.65.96.812.914.86.17.013.115.16.37.213.315.36.57.513.515.56.77.713.715.86.97.913.916.07.18.214.116.27.38.414.316.47.58.614.516.77.78.914.716.97.99.114.917.18.19.315.117.48.39.515.317.68.59.815.517.88.710.015.718.18.910.215.918.39.110.516.118.59.310.716.318.79.510.916.519.09.711.216.719.29.911.416.919.410.111.617.119.710.311.810.512.110.712.310.912.5a Or weight free of oedema b If weight on admission is pair, round the weight up with 0.1 kg. Example: weight on admission is 9.2 kg, use 9.3 kg as weight on admission. Annex 6. Routine Medicines Protocols Medicine/SupplementWhen to GiveAge / WeightPrescriptionDoseANTIBIOTICOn admissionAll beneficiariesAmoxicillin 50-100 mg/kg bodyweight/day3 times a day for 5 daysANTIMALARIAL (artemisinin-based combination therapy [ACT])Test on admission; Repeat test later if initial test negative and malaria suspected. If no test, rely on symptoms.All beneficiariesArtesunate (AS) 50 mg and Amodiaquine (AQ) 153 mg: AS and AQ 1 AS and 1 AQOnce a day for 3 daysANTIHELMINTHIC DRUG*After 1 week< 12 monthsDO NOT GIVENONE<10 kg e"10 kgAlbendazole 200 mg or Mebendazole 250 mg Albendazole 400 mg or Mebendazole 500 mgSingle doseMEASLES VACCINATION**Inpatient care: On admission and discharge Outpatient care: On week 4 (or upon discharge)From 6 monthsStandardSingle dose, or repeated dose**VITAMIN A*** SUPPLEMENTATIONOn week 4 (or upon discharge) 6 months e"12 months100,000 IU 200,000 IUSingle dose * An antihelminthic drug can be given again after three months if signs of re-infection appear. ** In case of measles epidemic, a measles vaccination is given on admission and repeated on week four (or upon discharge). If the child receives a measles vaccination before the age of 12 months, a repeat vaccination is given at the age of 12 months. ***Children with bilateral pitting oedema should not be given vitamin A until discharged. In case there are signs of vitamin A deficiency, children are treated in inpatient care (see Appendix). Note: Iron and folic acid should never be provided together with a malaria treatment. Malaria is treated first. Iron and folic acid should not be given in outpatient care. In case severe anaemia is identified according to the national Integrated Management of Childhood Illness (IMCI) guidelines, the child is treated in inpatient care (see Appendix). In inpatient care, if the child is on a therapeutic milk diet, he/she is given folic acid 5 mg on day one and 1 mg per day from day two onwards until discharge and iron 3 mg/kg bodyweight/day after two days on F100, when gaining weight. If the child is on a RUTF diet, neither folic acid nor iron is given. Annex 7. Supplementary Medicines Protocols Medicine/SupplementPurposePrescriptionSpecial InstructionsCHLORAMPHENICOL GENTAMYCINGiven as second-line antibiotic for children not responding to amoxicillin for continued fever that is not due to malaria Child with SAM who needs second-line antibiotic is referred to inpatient careSee Annex 8. Drug DosesContinue for 7 daysTETRACYCLINE EYE OINTMENTTreatment of eye infectionApply 3 times a day: morning, afternoon and at night before sleepWash hands before and after use. Wash eyes before application. Continue for 2 days after infection is goneNYSTATINTreatment of candida100,000 units (1 ml) 4 times a day after food (use dropper; show caregiver how to use it)Continue for 7 daysPARACETAMOL For children with fever over 38.5CSee Annex 8. Drug Doses Single dose onlyDO NOT give to take home BENZYL BENZOATE Treatment of scabiesApply over whole body. Repeat without bathing on following day. Wash off 24 hours later. Avoid contact with eyes. Do not use on broken or skin with secondary infection. WHITFIELDS Treatment of ringworm or fungal infections of the skinApply twice a day.Continue treatment until condition has completely resolved. GENTIAN VIOLET Treatment of minor abrasions or fungal infections of the skinApply on lesion.Can be repeated at next visit and continued until condition resolved QUININESecond-line antimalarial for children who have not responded to artemisinin-based combination therapy (ACT)See Annex 8. Drug Doses FERROUS SULPHATE/FOLATE Treatment of anaemia identified according to national Integrated Management of Childhood Illness (IMCI) guidelinesSee Annex 8. Drug DosesGiven ONLY after 14 days in the programme METRONIDAZOLEFor treatment of giardiasis and amoebiasis See Annex 8. Drug Doses Continue for 5 days Annex 8. Drug Doses SYSTEMATIC ANTIBIOTICS Antibiotics should be given to every severely malnourished child even if he/she does not show clinical signs of systemic infection. Small bowel bacterial overgrowth is frequently the source of systemic infection. Moreover in some of the severely malnourished children bacteria, such as Staphylococcus epidermidis can cause systemic infection or septicaemia. First-line antibiotics are always provided in outpatient and inpatient care. If a second-line antibiotic is needed, the child with severe acute malnutrition (SAM) is referred to inpatient care. Box 1. Antibiotic Regimen First-Line Oral Amoxicillin (if not available, use Ampicillin) Second-Line Add Chloramphenicol (do not stop Amoxicillin) OR Add Gentamycin (do not stop Amoxicillin) OR Change to Amoxicillin/Clavulinic acid (Augmentin) Third-Line Individual medical decision Note: Frequently a systemic anti-fungal (Fluconazole) is added if there are signs of severe sepsis or systemic candidiasis. The first line antibiotics will be given with the prophylactic Cotrimoxazole as a preventative therapy for HIV-positive children .Cotrimoxazole is not active against small bowel bacterial overgrowth in SAM.  Box 2. Duration of Antibiotic Treatment Inpatient Care Daily in stabilisation phase plus more days as appropriate Outpatient Care (if the child has not been in inpatient care) Five days Note: Paediatric antibiotic formulation is preferred.  Box 3. Administering Antibiotics Whenever possible, antibiotics should be given orally or, in special circumstances by nasogastric tube (NGT). Infusions containing antibiotics should not be used because of the risk of inducing heart failure. Indwelling cannulae should rarely be used. They can introduce antibiotic-resistant bacteria in immuno-compromised patients as the dressings get dirty easily. The cannulae often become colonised with candida, which can lead to fungal septicaemia. They also require fluid or anti-coagulants to keep the vein open, which could be harmful because children with SAM have impaired liver function that makes them sensitive to fluid overload. Misplacement of the cannula in the tissue or artery can cause necrosis.  Table 1. First-Line Antibiotic Treatment: Amoxicillin  Dose: 3 times a day for 5 days (50-100mg/kg bodyweight/day)Childs Age (or Weight)Syrup 125 mg/5mlSyrup 250 mg/5mlTablets 250 mg< 12 months (or < 10 kg)125 mg or 5 ml125 mg or 2.5 ml125 mg or tablet1- < 10 years (or 10-30 kg)250 mg or 10 ml250 mg or 5 ml250 mg or 1 tablet10 years+ (or > 30 kg)Give tabletsGive tablets500 mg or 2 tablets Table 2. Second-Line Antibiotic Treatment for Children With SAM Childs Weight (kg) Gentamycin IM* 5 mg/kg bodyweight/day Dose: Once a day for 7-10 daysChloramphenicol Oral** 50 mg/kg bodyweight/day Dose: 3 times a day for 7-10 days20 mg ampoule (10 mg/ml)Syrup 125 mgTablets or capsules 250 mg< 525 mg62.5 mg capsule5-1025- 50 mg125 mg capsule10-2050-100 mg250 mg1 capsule20-35100- 175 mg500 mg2 capsules> 35175 mg1,000 mg4 capsules* For Gentamycin, the 20 mg ampoule (10 mg/ml) should be used. It is difficult to measure small volumes with the stronger Gentamycin solution. **Chloramphenicol should never be used in infants under 2 months and should be used with caution in infants 2-6 months. VITAMIN A There is sufficient vitamin A in F75, F100 and ready-to-use therapeutic food (RUTF) to manage mild vitamin A deficiency and replace depleted liver stores during treatment. Because of vitamin As toxicity and the considerable amounts available in the therapeutic milk and RUTF, vitamin A is provided on week four (or on the day of discharge if before 4 weeks). For example, a 10 kilogram (kg) child taking maintenance amounts of F75 (1,000 kilocalories [kcal]) will receive about 7,300 international units (IU) (2.2 milligrams [mg]) of vitamin A per day. The United States (US) Recommended Daily Allowance (RDA) for such a child is 1,700 IU (0.5 mg) of vitamin A per day. Children with bilateral pitting oedema should not receive vitamin A while oedema is present. Vitamin A should never be give to a child who has received a dose in the last four months before admission, except in case of recent measles. Vitamin A is never given to infants under 6 months. Table 3. Vitamin A Systematic Treatment Age Vitamin A oral dose (IU)6-11 months100, 000 IU (one blue capsule)> 12 months (or e" 8 kg)200, 000 IU (one red capsule) Children with SAM are at high risk of developing blindness due to vitamin A deficiency, especially in areas with high baseline prevalence. If eye signs of vitamin A deficiency are identified, special care is required (See also in Appendix). Table 4. Vitamin A Treatment if Eye Signs of Vitamin A Deficiency or Recent Measles PRIVATE Child's Age Vitamin A Oral Dose Day 1 Day 2 Day 15< 6 months50,000 IU1 dose1 dose1 dose6-12 months100,000 IU1 dose1 dose1 dose>12 months200,000 IU1 dose1 dose1 dose MALARIA TREATMENT All severely malnourished children should be systematically screened for malaria. If the results are in clinical doubt, the test should be repeated in the week following the initial test. A persistently negative test excludes p. falciparum malaria. In the absence of screening methods, all children under five with SAM with clinical signs of malaria are treated with artemisinin-based combination therapy (ACT). Notes: The malaria load in children with bilateral pitting oedema might be low at testing. The usual clinical signs and symptoms of malaria might be absent in a severely malnourished child as they might be unable to mount an acute phase inflammatory response because of pathophysiological changes in their bodies. Children with SAM should not be given IV infusions of quinine within two weeks of treatment. Children with SAM should be given insecticide-treated bed nets, especially in malaria-endemic areas. In case of malaria with pneumonia or dysentery, ACT can be combined with amoxicillin and nalidixic acid but not with cotrimoxazole. Table 5. First-Line Antimalarial ACT: Artesunate (AS) and Amodiaquine (AQ)* Childs Age (or Weight ) Day 1 InitiallyDay 2Day 3 Total number of tablets< 4 kgNot recommended< 1 year (or 4-8 kg) AS and AQ AS and AQ AS and AQ31-5 years (or 9-15 kg)1 AS and 1 AQ1 AS and 1 AQ1 AS and 1 AQ65-15 years (or 16-35 kg)2 AS and 2 AQ2 AS and 2 AQ2 AS and 2 AQ12Adult (or >35 kg)4 AS and 4 AQ4 AS and 4 AQ4 AS and 4 AQ24*Artesunate (AS) 50 mg tablet; Amodiaquine (AQ) 153 mg tablet Table 6. Second-Line Antimalarial ACT: Coartem* [Combination of Artemether (20 mg) and Lumefantrine (120 mg)] Childs Age (or Weight ) Day 1 Initially Day 1 8 hours Day 2 morning Day 2 evening Day 3 morning Day 3 evening Total number of tablets< 2 months (or < 5 kg)Coartem is not recommended. Oral quinine (300 mg salt) is given instead: tablet 3 times a day for 7 days.2-24 months (or 5-14 kg)11111162-8 years (or 15-24 kg)222222128-12 years (or 25-34 kg)33333318> 12 (or > 35 kg)44444424* Coartem should be given with fatty meals to enhance absorption Table 7. Second-Line Antimalarial: Intramuscular (IM) Quinine Childs Age (or Weight) 300 mg/ml (quinine salt in 2 ml ampoules) at 10 mg/kg bodyweight /8 hours until child can take oral quinine to complete 7 daysAmount of undiluted quinineTotal diluted solution to administer (60 mg/ml)< 4 months (or 5-6 kg)0.2 ml1.0 ml-11 months (or 7-10 kg)0.3 ml1.5 ml1-2 years (or 11-14 kg)0.4 ml2.0 ml3-4 years (or 15-18 kg)0.6 ml3.0 ml5-7 years (or 19-24 kg)0.8 ml4.0 ml8-10 years (or 25-35 kg)1.1 ml5.5 ml11-13 years (or 36-50 kg)1.5 ml7.5 mlAdults (or > 50 kg)2.0 ml10 ml Table 8. Second-Line Antimalarial: Oral Quinine Childs Age (or Weight) 300 mg/ml tablets [quinine salt in 2 ml ampoules] for 7 daysQuinineFrequency3-12 months (or 5-10 kg) tablet3 times daily1-5 years (or 10-18 kg) tablet3 times daily5-7 years (or 18-24 kg) tablet3 times daily7-12 years (or 24-35 kg)1 tablet3 times daily10-15 years (or 35-50 kg)1.5 tablets3 times dailyAdults (or > 50 kg)2 tablets3 times daily Note: IM injections must be done with caution to reduce risk of abscess. In addition, quinine given when hypovolaemia is present can lead to shock and renal failure. Vital signs and urine flow must be monitored carefully before and during quinine treatment. DEWORMING TREATMENT In inpatient care, Albendazole or Mebendazole should be given at the start of the rehabilitation phase. Children admitted directly to outpatient care receive the antihelminthic drug after one week in treatment (i.e., at the second visit to outpatient care). Table 9. Antihelminthic Dose for Children With SAM  Child s Age Less than 1 year Child s Weight < 10 kg Child s Weight e" 10 kgAlbendazole 400 mg tabletNot given200 mg ( tablet) given once400 mg (1 tablet) given onceMebendazole 100 mg or 500 mg tabletNot given250 mg (2 tablets or tablet) given once500 mg (5 tablets or 1 tablet) given once MEASLES VACCINATION All children 6 months and older should be vaccinated if they cannot provide evidence of previous vaccination (e.g., vaccination card). In inpatient care, measles vaccinations are given at admission and upon discharge. In outpatient care, measles vaccinations are given on week four of the treatment (or upon discharge if discharge before four weeks). Children referred from inpatient care should also be vaccinated on week four if they did not receive the second vaccination in inpatient care. Children under 12 months receiving a measles vaccine, receive a repeat vaccination when reaching 12 months of age. Note: The measles vaccination given at admission in inpatient care often does not prompt a protective antibody response in a severely malnourished child. It ameliorates the severity of incubating measles and partially protects from nosocomial measles. The second dose provokes protective antibodies. In outpatient care, two vaccinations as is recommended in inpatient care, one at admission and one upon discharge, are usually unnecessary because there is limited risk of crowding and thus of transmission, except during a measles epidemic. PARACETAMOL Paracetamol is given as a single dose to children with fever, and antibiotic and/or malaria treatment are started immediately. Children with SAM with a fever over 38.5C are referred to inpatient care. Table 10. Paracetamol (Single Dose) Childs Weight (kg) Syrup (125 mg/5ml) Tablets (100 mg)< 4.025 mg (1 ml)25 mg ( tablet)4.0-7.960 mg (2.5 ml)50 mg ( tablet)8.0-14.9120 mg (5 ml)100 mg (1 tablet)> 15.0240 mg (10 ml)200 mg (2 tablets) RESOMAL ReSoMal is a rehydration solution for children with SAM provided in inpatient care only, after careful diagnosis of dehydration based on the childs medical history and clinical signs. The child is closely monitored while ReSoMal is administered. If the childs respiratory rate rises, bilateral pitting oedema (e.g., of eyelids) increases or neck veins become distended, ReSoMal is stopped. The child is reassessed after one hour. ReSoMal is always provided in controlled amounts and never given freely for use to the child and/or caregiver. Table 11. ReSoMal for Children With Marasmus and Dehydration Childs Weight (kg) First 30 minutes(ml) Second 30 minutes (ml) Second hour (ml)2.0-2.91010203.0-3.91515304.0-4.92020405.0-5.92525506.0-6.93030607.0-7.93535708.0-8.94040809.0-9.945459010.0-10.9505010011.0-11.9555511012.0-12.9606012013.0-13.9656513014.0-14.9707014015.0-15.97575150 If a child with bilateral pitting oedema has definite watery diarrhoea and the child is deteriorating clinically, then the fluid lost can be replaced on the basis of 30 ml of ReSoMal per watery stool. Do not use ReSoMal in case of cholera or profuse watery diarrhoea; use ORS instead. For ReSoMal recipes, see Annex 14. Alternative Recipes for F75, F100 and ReSoMal Using CMV. METRONIDAZOLE Metronidazole is used to treat giardiasis and amaebiasis. Table 12. Metronidazole* Childs Weight (kg) Metronidazole suspension 200 mg/5ml Metronidazole tablet 200 mg3-5.91 ml50 mg ( tablet)6-7.91.25 ml100 mg ( tablet)8-101.5 ml100 mg ( tablet)* 10 mg/kg bodyweight/day in 3 doses for 5 days IRON OR FOLIC ACID F75, F100 and RUTF contain sufficient iron and folic acid to treat mild anaemia and folate deficiency in a child with SAM. A 10 kg child taking maintenance amounts of the therapeutic diet will receive 400 micrograms (g) of folic acid per day. The Recommended Daily Allowance (RDA) for such a child is 80 g per day. Children diagnosed with anaemia according to Integrated Management of Childhood Illness (IMCI) are referred to inpatient care. Cotrimoxazole Prophylaxis for children with confirmed or suspected HIV infection Cotrimoxazole should be given to children starting at 4-6 weeks of age to: All infants born of mothers who are HIV-infected until HIV is definitively ruled out All infants <12 months with confirmed HIV infection or those with stage 2, 3 or 4 disease, or Asymptomatic infants or children with confirmed HIV infection (stage 1) if CD4 < 25% Table 13. Cotrimoxazole Dosage Single Dose Per Day Childs Age5 ml syrup 40 mg/200 mg Single strength adult tablet 80 mg/400 mgSingle strength paediatric tablet 20 mg/100 mg0-6 months2.5 ml tablet1 tablet6-59 months5 ml tablet2 tablets5-14 years10 ml1 tablet4 tablets>15 yearsNot given 2 tablets- OTHER NUTRIENTS F75, F100 and RUTF contain all the essential Type 1 and Type 2 nutrients required to treat and correct pathophysiological changes in a child with SAM. Additional potassium, magnesium or zinc should not be given to these children because a double dose could be toxic. Annex 9. Sugar Water Protocol SUGAR WATER 10 PERCENT DILUTION WaterSugar100 ml 10 g2 heaped teaspoons200 ml (average cup) 20 g4 heaped teaspoons500 ml (small bottle) 50 g10 heaped teaspoons1 litre 100 g20 heaped teaspoons Take clean drinking water (slightly warm if possible to help dilution) Add the required amount of sugar to clean drinking water and shake or stir vigorously. All children who have travelled for long distances or have waited a long time for attention should be given sugar water as soon as they arrive. Children with SAM can develop hypoglycaemia, though it is a very uncommon medical complication. A child who has taken the diet during the day will not develop hypoglycaemia overnight and does not need to be woken for night-time feeding. If the diet has not been taken during the day, the mother should give at least one feed during the night. Children that are at risk of hypothermia or septic shock should be given sugar water whether or not they have a low blood glucose level. (See Appendix.) Give sugar water immediately to all children refusing ready-to-use therapeutic food (RUTF) or being referred to inpatient care. If possible, especially when it is very hot, give to all children awaiting treatment in outpatient care. Annex 10. Appetite Test For children meeting the anthropometric criteria for admission for treatment for severe acute malnutrition (SAM), the appetite test, in addition to the presence or absence of severe medical complications, forms the most important criteria for deciding whether to treat a child with SAM in outpatient care or in inpatient care. The pathophysiological responses to nutrient depletion in children with SAM are such that liver and metabolic functions are disturbed and dysfunctional, leading to poor appetite. In addition children with a significant infection also lose appetite, especially in the acute phase. As a result, children with SAM with poor appetite face a higher risk of death. The appetite is tested upon admission and at each follow-up visit to the health facility in outpatient care. Points to consider: The appetite test is conducted in a quiet separate area to give the caregiver and child time to get accustomed to the ready-to-use therapeutic food (RUTF). The tests purpose and procedure are explained to the caregiver. The caregiver is advised to: Wash hands before giving the RUTF. Sit with the child in his/her lap and gently offer the RUTF. Encourage the child to eat the RUTF without force-feeding. Offer the child plenty of clean water, to drink from a cup, while the child eats the RUTF. If necessary, arrange a quiet corner where the child and caregiver can take their time to get accustomed to eat the RUTF. Usually the child eats the RUTF in 30 minutes. The child is observed for 30 minutes and then the health care provider determines whether the child passes or fails the test: Pass Fail Child eats at least one third of a 92g packet of RUTF or three teaspoons from a pot.Child does NOT eat one third of a 92g packet of RUTF or three teaspoons from a pot. A child who fails the appetite test has inappropriate appetite for taking the full therapeutic diet on RUTF and should be referred to inpatient care. Annex 11. Dietary Treatment OVERVIEW F75 75 kcal/100 ml Use: Inpatient care during stabilisation phase Diet: 100 kcal/kg bodyweight/day F100 100 kcal/100 ml Use: Inpatient care during transition and rehabilitation phases Diet: 150 and 200 kcal/kg bodyweight/day F100-Diluted 100 kcal/135 ml or 66 kcal/100 ml (add 35 ml water per 100 ml of F100) Use: Infants under 6 months (no oedema) in inpatient care during stabilisation phase, to complement breastfeeding Diet: 130 kcal/kg bodyweight/day Note: Infants with oedema in stabilisation phase start with F75 and change to F100 Diluted when the oedema is resolved. RUTF 500 kcal/92g Use: Outpatient care; Inpatient care during transition and rehabilitation phases Diet: 200 kcal/kg bodyweight/day  Table 1. Overview of Use of Therapeutic Foods in Inpatient Care for Children Under 5 DietUseF75Stabilisation phaseF100 (no iron added)Transition phaseF100 (iron added)Rehabilitation phaseF100-DilutedAll phases children under 6 months or under 4 kg without bilateral pitting oedemaRUTFTransition phase, before referral to outpatient care (if child upon admission to inpatient care has appetite, RUTF is offered from the start) Table 2. Overview of Dietary Treatment in Inpatient Care for Children 6-59 Months Stabilisation PhaseTransition PhaseRehabilitation PhaseObjectiveStabilising medical complication(s) and electrolyte and micronutrient deficienciesRecovering metabolism and organ functions Restoring body functionConditionChild has poor appetite or is clinically unwell.Child has appetite and is alert and clinically well.Child catches up weight.Duration of stay2-7 days2-3 days Referred to outpatient care as soon as appetite test is passed(1-4 weeks) Referred to outpatient care as soon as appetite test is passed; some rare cases remain in inpatient care until full recovery Therapeutic foodF75RUTF and/or F100RUTF or F100Amount130 ml/kg bodyweight/day of F75 in 8-6 meals130 ml/kg bodyweight/day of F100 or RUTF in 8-6 meals200 ml/kg bodyweight/day of F100 or RUTF in 6-5 mealsEnergy 100 kcal/kg bodyweight/day150 kcal/kg bodyweight/day200 kcal/kg bodyweight/dayExpected Weight gain NoneAverage 5 g/kg bodyweight/daySubstantial e"10 g/kg bodyweight/day THERAPEUTIC MILK F75 and F100 are therapeutic products that are available commercially as powder formulations. They can also be prepared using basic ingredients of milk, sugar, cereal flour, vegetable oil and combined mineral and vitamin mix (CMV) for SAM (see Annex 14. Alternative Recipes for F75, F100 and ReSoMal Using CMV). F75 F75 provides 75 kilocalories (kcal) per 100 millilitres (ml) and has the correct balance of Type 1 and Type 2 nutrients, a greater nutrient density and bioavailability, and lower osmolarity and renal solute load. It is designed to restore hydration and electrolyte and metabolic balance, and provide the necessary calories and nutrients for maintenance needs and for starting the restoration of adequate immune function. The amount of F75 given in the stabilisation phase is 100 kcal/130 ml/kg bodyweight/day. F75 is provided in inpatient care during the stabilisation phase ONLY. F100 F100 provides 100 kcal/100 ml and has the correct balance of Type 1 and Type 2 nutrients and a greater nutrient density and bioavailability. It is designed to provide adequate calories and nutrients to promote catch-up growth in children recovering from SAM. The amount of F100 given in the transition phase is 130 kcal/130 ml/kg bodyweight/day. The amount given in the rehabilitation phase is 200 kcal/200 ml/kg bodyweight/day, F100 is provided in inpatient care during the transition and rehabilitation phases. It should NEVER be given in outpatient care or for use at home. F100-Diluted F100-Diluted has 74 kcal/100 ml, as one-third more water is added to the F100 mixture. It provides adequate calories and nutrients with lower osmolarity and renal solute load then F75 and F100 which is better adapted for immature organs. The amount of F100-Diluted given in the initial phase is 100 kcal/130 ml/kg bodyweight/day and gradually increases in the weight gain phase to 150 kcal/200ml/kg bodyweight/day. F100-Diluted is provided in inpatient care in all phases for infants under 6 months or less than 4 kg if no bilateral pitting oedema, as it provides adequate calories and nutrients to restore electrolyte and metabolic balance, and promotes catch-up growth in infants recovering from SAM when given in higher quantities. Table 3. Therapeutic Milk Specifications Constituent F75 Amount in 100 mlF100 Amount in 100 mlF100 Amount in 100 ml (approximation)Energy75 kcal100 kcal74 kcalProteins0.9 g2.9 g2.1 gLactose1.3 g4.2 g3.1 gPotassium3.6 mmol5.9 mmol4.1 mmolSodium0.6 mmol1.9 mmol1.4 mmolMagnesium0.43 mmol0.73 mmol0.54 mmolZinc2.0 mg2.3 mg1.7 mgCopper 0.25 mg0.25 mg0.1 mg% of energy from protein5 %12 %12 %% of energy from fat32 %53 %53 %Osmolarity333 mOsmol/L419 mOsmol/L310 mOsmol/L READY-TO-USE THERAPEUTIC FOOD (RUTF) RUTF are soft foods or pastes specifically developed with the right mix of Type 1 and Type 2 nutrients and caloric composition to treat a child over 6 months with SAM. It is easy for children to eat, and it requires no preparation and no mixing with water or other foods. It has a similar nutrient and caloric composition to F100 but has very low water activity, which means bacteria cannot grow in it. This allows it to be given as a take-home ration in outpatient care. It can also be provided in inpatient care during the transition and rehabilitation phases. Plumpynut is a commercial RUTF manufactured by Nutriset. It comes in 500 kcal packets weighing 92 g. RUTF can also be produced locally with dried skim milk, sugar, oil, CMV and peanut paste. Table 4. RUTF Protocol, Based on 200 Kcal/kg Bodyweight/Day Childs Weight (kg)Packets per Week (500 kcal/92 g packet)Packets per Day4.0* 4.91425.0 6.9182.57.0 8.42138.5 9.4253.59.5 10.428410.5 11.9324.5( 12355* Infants < 4 kg are referred to inpatient care RUTF Specifications See Annex 16. RUTF Specifications. COMBINED MINERAL VITAMIN MIX (CMV) CMV or vitamin and mineral mix complies with the recommendations for vitamin and mineral enrichment in the dietetic treatment of SAM. It is used to prepare F100, F75 and ReSoMal (from the current ORS [WHO formula] + sugar + water). It comes in an airtight metallic tin with a red measuring scoop that holds 6.35 g of mix, enough to prepare 2 L of F75, F100 or ReSoMal. CMV has a shelf life of 24 months from manufacturing date. The mineral mix should have a moderate positive non-metabolisable base sufficient to eliminate the risk of metabolic acidosis. The non-metabolisable base can be approximated by the formula: estimated absorbed millimoles (mmol) (sodium +potassium + calcium + magnesium) - (phosphorus + chloride). The mineral mix reproduced below has a suitable positive non-metabolisable base. Its shelf life is 24 months from the manufacturing date. CMV Specifications Table 5. Nutritional Value of Commercial CMV (per 6.35 g or 1 levelled scoop) VitaminsMineralsBiotin: 0.2 mg Folic acid: 700 g Niacin: 20 mg Pantothenic acid: 6 mg Vitamin A: 3,000 g Vitamin B1: 1.4 mg Vitamin B12: 2 g Vitamin B2: 4 mg Vitamin B6: 1.4 mg Vitamin C: 200 mgVitamin D: 60 g Vitamin E: 44 mg Vitamin K: 80 g Copper: 5.7 mg Iodine: 154 g Iron: 0 mg Magnesium: 146 mg Potassium: 2,340 mg Selenium: 94 g Zinc: 40 mg Annex 12. Therapeutic Feeds Look-Up Tables F-75 LOOK-UP TABLES Volume of F-75 for Children with Severe Wasting Weight of Child (kg)Volume of F-75 per feed (ml)aDaily total (130 ml/kg)80% of daily total a (minimum)Every 2 hoursb (12 feeds)Every 3 hoursc (8 feeds)Every 4 hours (6 feeds)2.02030452602102.22535502862302.42540553122502.63045553382652.83045603642903.03550653903103.23555704163353.43555754423553.64060804683753.84060854943954.04565905204154.24570905464354.45070955724604.650751005984804.855801056245005.055801106505205.255851156765405.460901207025605.660901257285805.865951307546056.0651001307806256.2701001358066456.4701051408326656.6751101458586856.8751101508847057.0751151559107307.2801201609367507.4801201609627707.6851251659887907.88513017010148108.09013017510408308.29013518010668558.49014018510928758.69514019011188958.89514519511449159.010014520011709359.210015020011969609.410515520512229809.6105155210124810009.81101602151274102010.011016022013001040a Volumes in these columns are rounded to the nearest 5 ml. b Feed two-hourly for at least the first day. Then, when the child has little or no vomiting, modest diarrhoea (< 5 watery stools per day), and is finishing most feeds, change to three-hourly feeds. c After a day on three-hourly feeds: If no vomiting, less diarrhoea, and finishing most feeds, change to four-hourly feeds. Volume of F-75 for Children with Severe Bilateral Pitting Oedema (+++) Weight with +++ oedema (kg)Volume of F-75 per feed (ml)aDaily total (100 ml/kg)80% of daily totala (minimum)Every 2 hoursb (12 feeds)Every 3 hoursc (8 feeds)Every 4 hours (6 feeds)3.02540503002403.22540553202553.43045603402703.63045603602903.83050653803054.03550654003204.23555704203354.43555754403504.64060754603704.84060804803855.04065855004005.24565855204155.44570905404305.64570955604505.85075955804656.050751006004806.250801056204956.455801056405106.655851106605306.855851156805457.060901157005607.260901207205757.460951257405907.665951257606107.8651001307806258.0651001358006408.2701051358206558.4701051408406708.6701101458606908.8751101458807059.0751151509007209.2751151559207359.4801201559407509.6801201609607709.88012516598078510.085125165100080010.285130170102081510.485130175104083010.690135175106085010.890135180108086511.090140185110088011.295140185112089511.495145190114091011.695145195116093011.8100150195118094512.01001502001200960a Volumes in these columns are rounded to the nearest 5 ml. b Feed two-hourly for at least the first day. Then, when the child has little or no vomiting, modest diarrhoea (< 5 watery stools per day), and is finishing most feeds, change to three-hourly feeds. c After a day on three-hourly feeds: If no vomiting, less diarrhoea, and finishing most feeds, change to four-hourly feeds. F-100 LOOK-UP TABLE Range of Volumes for Free-Feeding With F-100 Weight of Child (kg)Range of volumes per four-hourly feed of F-100 (6 feeds daily)Range of daily volumes of F-100Minimum (ml)Maximum (ml) aMinimum (150 ml/kg/day)Maximum (220 ml/kg/day)2.050753004402.255803304842.460903605282.665953905722.8701054206163.0751104506603.2801154807043.4851255107483.6901305407923.8951405708364.01001456008804.21051556309244.41101606609684.611517069010124.812017572010565.012518575011005.213019078011445.413520081011885.614020584012325.814521587012766.015022090013206.215523093013646.416023596014086.616524099014526.8170250102014967.0175255105015407.2180265108015887.4185270111016287.6190280114016727.8195285117017168.0200295120017608.2205300123018048.4210310126018488.6215315129018928.8220325132019369.0225330135019809.2230335138020249.4235345141020689.6240350144021129.82453601470215610.025036515002200a Volumes per feed are rounded to the nearest 5 ml. RUTF LOOK-UP TABLES: AMOUNTS OF RUTF TO GIVE TO A CHILD PER DAY RUTF Dose of 150 kcal/kg Bodyweight/Day Using 92 g Packets Containing 500 kcal Childs Weight (kg)Packets per Day3.5 3.91.24.0 4.91.55.0 6.92.17.0 8.42.58.5 9.42.89.5 10.43.110.5 11.93.6( 124 RUTF Dose of 200 kcal/kg Bodyweight/Day Using 92 g Packets Containing 500 kcal Childs Weight (kg)Packets per Day3.5 3.91.54.0 4.925.0 6.92.57.0 8.438.5 9.43.59.5 10.4410.5 11.94.5( 125 Annex 13. Danger Signs for Inpatient Care Danger Signs Related to Pulse, Respirations and Temperature Alert a physician if these occur. Danger sign:Suggests:Pulse and RespirationsConfirmed increase in pulse rate of 25 or more beats per minute along with Confirmed increase in respiratory rate of 5 or more breaths per minuteInfection or Heart failure (possibly from overhydration due to feeding or rehydrating too fast)Respirations Only Fast breathing: 50 breaths/minute or more in child 2 months up to 12 months old* 40 breaths/ minute or more in child 12 months up to 5 yearsPneumoniaTemperatureAny sudden increase or decrease Rectal temperature below 35.5(C (95.9(F)Infection Hypothermia (possibly due to infection, a missed feed, or child being uncovered) In addition to watching for increasing pulse or respirations and changes in temperature, watch for other danger signs such as: Anorexia (loss of appetite) Change in mental state (e.g., becomes lethargic) Jaundice (yellowish skin or eyes) Cyanosis (tongue/lips turning blue from lack of oxygen) Difficult breathing Difficulty feeding or waking (drowsy) Abdominal distention New oedema Large weight changes Increased vomiting Petechiae (bruising) Normal Ranges of Pulse and Respiratory Rates AgeNormal ranges (per minute):PulseRespirations2 months up to 12 months80 up to 16020 up to 60*12 months up to 60 months (5 years)80 up to 14020 up to 40*Some children 2-12 months of age will normally breathe fast (i.e., 50-60 breaths per minute) without having pneumonia. However, unless the childs normal respiratory rate is known to be high, he/she should be assumed to have either overhydration or pneumonia. Careful evaluation, taking into account prior fluid administration, will help differentiate the two conditions and plan appropriate treatment. Annex 14. Alternative Recipes for F75, F100 and ReSoMal Using CMV F75 FORMULA Type of milkMilk (g)Sugar (g)Oil (g)Cereal powder* (g)CMV red scoop (6.35 g)Water (ml)Dry skim milk5014054701Add cooled boiled water up to 2,000 mlDry whole milk7014040701Fresh cow milk56013040701Fresh goat milk56013040801*Cereal powder is cooked for about 10 minutes before the other ingredients are added. To prepare F75, add the milk, sugar, pre-boiled cereal powder and oil to one litre (L) water and mix. Boil for 5-to-7 minutes. Allow to cool, add the combined mineral and vitamin mix (CMV) and mix again. Make up the volume to 2,000 millilitres (ml) with cooled boiled water. F100 FORMULA Type of milkMilk (g)Sugar (g)Oil (g)CMV red scoop (6.35 g)Water (ml)Dry skim milk1601001201Add cooled boiled water up to 2,000 mlDry whole milk220100601Fresh cow milk1,800100501Fresh goat milk1,800100601 To prepare F100, add the milk, sugar, and oil to one litre water and mix. Boil for 5-to-7 minutes. Allow to cool, add the CMV and mix again. Make up the volume to 2,000 ml with cooled boiled water. RESOMAL IngredientAmountStandard WHO ORS1 L packageCMV1 red scoop (6.35 g)Sugar50 gWaterUp to 2,000 ml IngredientAmountLow Osmolarity WHO ORS1 L packageCMV1 red scoop (6.35 g)Sugar40 gWater1,700 ml IngredientAmountLow Osmolarity WHO ORS1/2 L packageCMV1/2 red scoop (3.18 g)Sugar20 gWater850 ml To prepare ReSoMal from oral rehydration solution (ORS), add CMV and sugar to one package of ORS, and add cooled boiled water following the above recipes. To prepare ReSoMal from commercial sachets, add one sachet of 84g to 2 L water and mix. ReSoMal Specifications Per 1 L constituentReSoMal AmountSodium45 mmolChloride70 mmolPotassium40 mmolCitrate7 mmolGlucose55 mmolSaccharose73 mmolMagnesium3 mmolZinc300 molCopper Osmolarity4 mol 294 mmol/L Standard and Reduced Osmolarity ORS Specifications Per 1 L constituentStandard ORS Amount Per 1 L constituentReduced ORS AmountSodium90 mmolSodium75 mmolChloride80 mmolChloride65 mmolPotassium20 mmolPotassium20 mmolCitrate10 mmolCitrate10 mmolGlucose 111 mmolGlucose 75 mmolOsmolarity 251 mmol/LOsmolarity 245 mmol/L Annex 15. Use of Home-Modified Cow Milk for Replacement Feeding in Case of No Access to Infant Formula Modifying animal milk for feeding infants under 6 months raises difficult technical challenges. First, the currently recommended recipe would need an increased essential fatty acid content. This involves adding daily small amounts of seven vegetable oils in quantities that would need to be adjusted to their essential fatty acid composition and to the childs weight. The feasibility of this approach has never been tested in the field. Second, the present recommendation of adding a mineral and vitamin mix to the recipe has not proved feasible to implement in practice, even on a pilot scale. Giving a mineral and vitamin supplement once a day to the child as a drug or mixed with a feed might be possible, although the safety of this approach would be a concern if the supplement contains iron. In view of both the technical difficulties of formulating and preparing a nutritionally adequate recipe for home-modified animal milk and the lack of data on the safety of this milk for replacement feeding of infants under 6 months, home-modified animal milk should not be recommended as a feasible and safe long-term replacement feeding option. Only in situations where access to commercial infant formula has been temporarily interrupted should home-modified animal milk be considered for short-term feeding of non-breastfed infants under 6 months. Recipes for Home-Prepared Infant Formula with Fresh Cow Milk, for Short Term Emergency Feeding of Infants under 6 months Quantity of fresh cow milk (ml)Added water (ml)Added sugar (g)Amount of prepared formula (ml)40204606030690804081201005010150 Annex 16. RUTF Specifications Children with severe acute malnutrition (SAM) require specialised therapeutic food to recover, such as F100 and F75 therapeutic milk. Ready-to-use therapeutic food (RUTF) is an integral part of outpatient care as it allows children to be treated at home rather than at inpatient treatment centres. RUTF is an energy-dense mineral/vitamin enriched food that is equivalent to F100. There are currently two commercial types of RUTF: Plumpynut and BP 100. Several countries are producing their own RUTF using recipes that are adapted to locally available ingredients. Their products have similar nutritional quality as F100 and have been shown to be physiologically similar to commercial forms of F100 and RUTF. PLUMPYNUT PlumpyNut is a ready-to-eat therapeutic spread presented in individual sachets. It is a groundnut paste composed of vegetable fat, peanut butter, skimmed milk powder, lactoserum, maltodextrin, sugar, and mineral and vitamin complex. Instructions for Use Clean drinking water must be made available to children while they consume ready-to-eat therapeutic spread. The product should be given only to children who can express their thirst. Recommendations for Use It is recommended to use the product in the rehabilitation phase in the dietetic management of SAM. In the stabilisation phase, a milk-based diet is used (F75). However, Plumpynut is contraindicated for children who are allergic to cow milk, proteins or peanut and for people with asthma due to risk of allergic response. Storage and Packaging Plumpynut has a shelf life of 24 months from manufacturing date and should be stored in a cool and dry place. It comes in a 92g packet that contains 500 kcal. A carton (around 15.1 kg) contains 150 packets. Table 1. Mean Nutritional Value of PlumpyNut NutrientsAmount For 100 gPer sachet of 92 gNutrientsAmount For 100 gPer sachet of 92 gEnergy545 kcal500 kcalVitamin A910 g840 gProteins13.6 g12.5 gVitamin D16 g15 gLipids35.7 g32.86 gVitamin E20 mg18.4 mgCalcium300 mg276 mgVitamin C53 mg49 mgPhosphorus300 mg276 mgVitamin B10.6 mg0.55 mgPotassium1,111 mg1,022 mgVitamin B21.8 mg1.66 mgMagnesium92 mg84.6 mgVitamin B60.6 mg0.55 mgZinc14 mg12.9 mgVitamin B121.8 g1.7 gCopper1.8 mg1.6 mgVitamin K21 g19.3 gIron11.5 mg10.6 mgBiotin65 g60 gIodine100 g92 gFolic acid210 g193 gSelenium30 g27.6 gPantothenic acid3.1 mg2.85 mgSodium< 290 mg< 267 mgNiacin5.3 mg4.88 mg PRODUCTION OF RUTF The required ingredients for producing RUTF are sugar, dried skim milk, oil and a vitamin and mineral supplement. Up to 25 percent of the weight of the product can come from vegetable sources such as oil seeds, groundnuts or cereals such as oats. In addition to good nutritional quality (protein, energy and micronutrients), RUTF should have the following attributes: Taste and texture suitable for young children No need for additional processing such as cooking before consumption Resistant to contamination by microorganisms and a long shelf life without sophisticated packaging Ingredients that are low cost and readily available in developing countries RUTF Specifications Nutrient AmountMoisture content2.5% maximumEnergy520-550 kcal/100 gProteins*10 to 12% total energyLipids45 to 60% total energySodium290 mg/100 g maximumPotassium1100 to 1400 mg/100 gCalcium300 to 600 mg/100 gPhosphorus (excluding phytate)300 to 600 mg/100 gMagnesium80 to 140 mg/100 g Iron**10 to 14 mg/100 gZinc11 to 14 mg/100 gCopper 1.4 to 1.8 mg/100 gSelenium20 to 40 gIodine70 to 140 g/100 gVitamin A0.8 to 1.1 mg/100 gVitamin D15 to 20 g/100 gVitamin E20 mg/100 g minimumVitamin K15 to 30 g/100 gVitamin B10.5 mg/100 g minimumVitamin B21.6 mg/100 g minimumVitamin C50 mg/100 g minimumVitamin B60.6 mg/100 g minimumVitamin B121.6 g/100 g minimumFolic acid200 g/100 g minimumNiacin5 mg/100 g minimumPantothenic acid3 mg/100 g minimumBiotin60 g/100 g minimumn-6 fatty acids3% to 10% of total energyn-3 fatty acids0.3 to 2.5% of total energy*At least half of the proteins contained in the product should come from milk products. ** Iron is already added to RUTF, in contrast to F100. Safety The food must be kept free from objectionable matter. It must not contain any substance originating from microorganisms or any other poisonous or deleterious substances like anti-nutritional factors, heavy metals or pesticides in amounts that might represent a hazard to health of severely malnourished patients. Table 2. RUTF Safety Specifications Aflatoxin level 5 ppb maximum Microorganism content10,000/g maximumColiform test negative in 1 gClostridium perfringens negative in 1 gYeast maximum 10 in 1 gMoulds maximum 50 in 1 gPathogenic staphylococcinegative in 1 gSalmonella negative in 125 gListeria negative in 25 g  The product should comply with the International Code of Hygienic Practice for Foods for Infants and Children of the Codex Alimentarius Standard CAC/RCP 21-1979. All added mineral and vitamins should be on the Advisory List of Mineral Salts and Vitamin compounds for Use in Foods for Infants and Children of the Codex Alimentarius Standard CAC/GL 10-1979. The added minerals should be water soluble and should not form insoluble components when mixed together. More information on how to produce RUTF is available at: HYPERLINK "http://www.who.int/child-adolescent%20health/New_Publications/NUTRITION/CBSM/tbp_4.pdf"http://www.who.int/child-adolescent health/New_Publications/NUTRITION/CBSM/tbp_4.pdf. Annex 17. Action Protocol in Outpatient Care SignReferraltoInpatient CareHomeVisit GENERAL CONDITIONDeteriorating Child is absent or defaulting Child is not gaining weight or losing weight on follow-up visit Child is not losing oedema Child has returnedfrom inpatientcare or refuses referraltoinpatient careBILATERAL PITTING OEDEMAGrade+++Any grade of bilateral pitting oedema with severe wasting (marasmic kwashiorkor)Increasein bilateral pitting oedemaBilateral pitting oedemanot reducing by week 3ANOREXIA *Poorappetiteorunabletoeat Failed appetite testVOMITING *Intractable vomitingCONVULSIONS *Ask mother if the child had convulsions during the since the previous visitLETHARGY, NOT ALERT *Child is difficult to awakeUNCONSCIOUSNESS *Child does not respond to painful stimuliHYPOGLYCAEMIAA clinical sign in a child with SAM is eye-lid retraction: child sleeps with eyes slightly open. Low level of HYPERLINK "http://en.wikipedia.org/wiki/Blood_glucose" \o "Blood glucose"blood glucose < 3 mmol/l, < 54 mg/dlDEHYDRATIONSevere dehydration based primarily on recent history of diarrhoea, vomiting, fever or sweating and on recent appearance of clinical signs of dehydration as reported bythemother/caregiverHIGH FEVERAxillary temperature e" 38.5 C, rectal temperature e" 39 C taking into consideration the ambient temperatureHYPOTHERMIAAxillary temperature < 35 C, rectal temperature < 35.5 C taking into consideration the ambient temperatureRESPIRATIONRATEe"60respirations/minuteforchildren under2months e"50respirations/minutefrom2-12months e"40respirations/minutefrom1-5 years e"30respirations/minuteforchildren over5 years Anychestin-drawingANAEMIA Palmerpallor or unusual paleness of skinSKIN LESIONBroken skin, fissures, flaking of skinSUPERFICIAL INFECTION Any infectionrequiringintramuscular antibiotic treatment WEIGHTCHANGESBelowadmissionweightonweek3 WeightlossforthreeconsecutivevisitsStaticweightforthreeconsecutivevisitsREQUESTMother/caregiverrequeststreatment of child in inpatientcare for social reasons (decided by supervisor)NOTRESPONDINGChild that is not responding to treatment is referred to inpatient care or hospital for further medical investigation.* Integrated Management of Childhood Illness (IMCI) danger signs Annex 18. Key Messages Upon Admission to Outpatient Care RUTF is a food and medicine for very thin and swollen children only. Do not share it. Sick children often dont like to eat. Give small regular meals of RUTF and encourage the child to eat often (if possible, 8 meals a day). Your child should have _______ packets a day. For young children, continue to breastfeed. Offer breast milk first before every RUTF feed. RUTF is the only food sick and thin/swollen children need to recover during their time in Outpatient Care. Always give RUTF before other foods, such as porridge (use local name). Always offer the child plenty of clean water to drink while eating RUTF. Children will need more water than normal. Wash the childs hands and face with soap before feeding. Keep food clean and covered. Sick children get cold quickly. Always keep the child covered and warm. For children with diarrhoea, continue feeding. Give them extra food and water. Return to the health facility whenever the childs condition deteriorates or if the child is not eating sufficiently. Note: Ask the caregiver to repeat the messages to be sure they have been correctly understood. Upon the next visits to the health facility, the health and nutrition messages are expanded (see Annex 19. Health and Nutrition Education Messages). Annex 19. Health and Nutrition Education Messages KEY BEHAVIORS TO PROMOTE Essential Nutrition Actions Optimal breastfeeding during the first 6 months of life Optimal complementary feeding starting at 6 months with continued breastfeeding to 2 years of age and beyond Continued feeding when the child is ill Optimal nutrition care of malnourished children Prevention of vitamin A deficiency for women and children Adequate iron and folic acid intake, and the prevention and control of anaemia for women and children Adequate iodine intake by all members of the household Optimal nutrition for women Household Hygiene Actions Treatment and safe storage of drinking water Handwashing with soap or ash at critical times: after defecation, after handling childrens faeces, before preparing food, before feeding children, before eating Safe disposal of faeces Proper storage and handling of food to prevent contamination Other Care Practices Antenatal care attendance, including: at least four visits, tetanus toxod vaccine, iron/folic acid supplementation Full course of immunisations for all children before their first birthday Children and women sleeping under insecticide-treated bednets Recognition when a sick child needs treatment outside of the home and seeking care from appropriate providers Recognition of pregnancy danger signs 2. IMPORTANCE OF BREASTFEEDING Importance of Breastfeeding for the Infant/Young Child Breast Milk: Saves infants lives Is a whole food for the infant, and contains balanced proportions and sufficient quantity of all the needed nutrients for the first 6 months Promotes adequate growth and development, thus preventing stunting Is always clean Contains antibodies that protect against diseases, especially against diarrhoea and respiratory infections Is always ready and at the right temperature Is easy to digest; nutrients are well absorbed Protects against allergies; breast milk antibodies protect the babys gut preventing harmful substances to pass into the blood Contains enough water for the babys needs (87% of water and minerals) Helps jaw and teeth development; suckling develops facial muscles Provides frequent skin-to-skin contact between mother and infant, which leads to better psychomotor, affective and social development of the infant Provides the infant with benefits from the colostrum, which protects him/her from diseases; the amount is perfect for newborn stomach size Promotes brain development; increased Intelligence Quotient (IQ) scores Importance of Breastfeeding for the Mother Putting the baby to the breast immediately after birth facilitates the expulsion of placenta because the babys suckling stimulates uterine contractions Reduces risks of bleeding after delivery When the baby is immediately breastfed after birth, breast milk production is stimulated Breastfeeding is more than 98% effective as a contraceptive method during the first 6 months provided that breastfeeding is exclusive and amenorrhea persists Immediate and frequent suckling prevents engorgement Reduces the mothers workload (no time is involved in boiling water, gathering fuel, preparing milk) Breastmilk is available at anytime and anywhere, is always clean, nutritious and at the right temperature It is economical Stimulates bond between mother and baby Reduces risks of breast and ovarian cancer Importance of Breastfeeding for the Family The child receives the best possible quality of food, no matter what the familys economic situation No expenses in buying formula, firewood or other fuel to boil water, milk or utensils; the money saved can be used to meet the familys other needs No medical expenses due to sickness that formula could cause; the mothers and their children are healthier As illness episodes are reduced in number, the family encounters few emotional problems associated with the babys illness Births are spaced thanks to the contraceptive effect Time is saved Feeding the baby reduces work because the milk is always available and ready Importance of Breastfeeding for the Community Not importing formula and utensils necessary for its preparation saves hard currencies that could be used for something else Healthy babies make a healthy nation Savings are made in the health area; a decrease in the number of child illnesses leads to decreased national medical expenses Improves child survival; reduces child morbidity and mortality Protects the environment (trees are not used for firewood to boil water, milk and utensils, thus protecting the environment); breast milk is a natural renewable resource 3. RECOMMENDED IYCF PRACTICES Recommended Breastfeeding Practices and Possible Points of Discussion for Counselling Recommended Breastfeeding PracticePossible Points of Discussion for Counselling (Choose most relevant to mothers situation)Put infant skin-to-skin with mother immediately after birth. Skin-to-skin with mother keeps newborn warm. Skin-to-skin with mother helps stimulate brain development. Initiate breastfeeding within the first hour of birth. This first milk local word is called colostrum. It is yellow and full of antibodies which help protect your baby. Colostrum provides the first immunization against many diseases. Breastfeeding from birth helps the milk come in and ensures plenty of breast milk.Exclusively breastfeed (no other food or drink) for 6 months.Breast milk is all the infant needs for the first 6 months. Do not give anything else to the infant before 6 months, not even water Giving water will fill the infant and cause less suckling; less breast milk will be produced.Breastfeed frequently, day and night. Breastfeed the baby often, at least 8-12 times for a newborn and 8 or more times after breastfeeding is well-established, day and night, to produce lots of breast milk. More suckling (with good attachment) makes more breast milk.Breastfeed on demand (or cue) every time the baby asks to breastfeed.Crying is a late sign of hunger. Early signs that baby wants to breastfeed: Restlessness Opening mouth and turning head from side to side Putting tongue in and out Sucking on fingers or fistsLet infant finish one breast and come off by him/herself before switching to the other breast.Switching back and forth from one breast to the other prevents the infant from getting the nutritious hind milk. The fore milk has more water content and quenches infants thirst; the hind milk has more fat content and satisfies the infants hunger.Continue breastfeeding until 2 years of age or longer.Breast milk contributes a significant proportion of energy and nutrients during the complementary feeding period and helps protect babies from illness. In the first year, breastfeed before giving foods to maintain breast milk supply.Mother needs to eat and drink to satisfy hunger and thirst.No one special food or diet is required to provide adequate quantity or quality of breast milk. Breast milk production is not affected by maternal diet. No foods are forbidden. Mothers should be encouraged to eat supplemental foods where they are accessible.Avoid feeding bottles.Foods or liquids should be given by a spoon or cup to reduce nipple confusion and the possible introduction of contaminants. Recommended Complementary Feeding Practices AgeFrequency (per day)Amount of food an average child will usually eat at each serving* (in addition to breast milk)Texture (thickness/ consistency)Variety6-8 months 2-3 times food 2-3 tablespoons Tastes up to cup (250 ml) Thick porridge/pap Mashed/ pureed family foods** Breastfeeding + staples (porridge, other local examples) Legumes (local examples) Vegetables/fruits (local examples) Animal foods (local examples) 9-11 months 4 times foods and snacks  cup/bowl (250 ml) Finely chopped family foods Finger foods Sliced foods 12-23 months 5 times foods and snacks  -1 cup/bowl (250 ml) Family foods Sliced foods Note: If baby is not breastfed Add 1-2 extra times food and snacks Add 1-2 cups of milk per day Responsive/active feeding Be patient and actively encourage your baby to eat. Hygiene Feed your baby using a clean cup and spoon, never a bottle, as this is difficult to clean and may cause your baby to get diarrhoea. Wash your hands with soap and water before preparing food, eating and feeding young children. *Adapt the chart to use a suitable cup/bowl to show the amount. The amounts assume an energy density of 0.8 1 kcal/g. ** Use iodized salt in preparing family foods. Recommended Complementary Feeding Practices and Possible Points of Discussion for Counselling Recommended Complementary Feeding Practice Possible Points of Discussion for Counselling (choose most relevant to mothers situation) At 6 months of age, add complementary foods (e.g., thick porridge 2-3 times a day) to breastfeeds.Give local examples of first types of complementary foods.As baby grows older, increase feeding frequency, amount, texture and variety.FATV: Gradually increase the frequency (F), amount (A), texture (T) (thickness/consistency) and variety (V) of foods.From 6-8 months of age, breastfeed plus give 2-3 servings of foods.Start with 2-3 tablespoonfuls of cooked porridge or mashed foods (give examples of cereals and family foods). At 6 months, these foods are more like tastes than actual servings. Increase gradually to cup (250 ml cup). Show amount in cup brought by mother.From 9-11 months of age, breastfeed plus give 4 servings of food or snacks per day. Give finely chopped, mashed foods and finger foods. Increase gradually to cup (250 ml cup). Show amount in cup brought by mother. From 12-23 months of age, give 5 servings of food or snacks per day, plus breastfeed.Give family foods. Give to one cup (250 ml cup/bowl). Show amount in cup brought by mother. Other solid foods (snacks) can be given as many times as possible each day and can include [give examples]. Foods given to the child must be stored in hygienic conditions to avoid diarrhoea and illness. Give baby 2-3 different family foods: staple, legumes, vegetables/fruits, and animal foods at each serving. Try to feed different foods at each serving. Continue breastfeeding until 2 years of age or longer.During the first and second years, breast milk is an important source of nutrients for your baby. During the first year, breastfeed first to maintain breast milk supply.Be patient and actively encourage baby to eat all his/her food. At first, baby may need time to get used to eating foods other than breast milk. Use a separate plate to feed the child to make sure he/she eats all the food given.Wash hands with soap and water before preparing food, eating and feeding young children.Foods given to the child must be stored in hygienic conditions to avoid diarrhoea and illness.Feed baby using a clean cup and spoon. Cups are easy to keep clean.  4. RECOMMENDED FOODS FOR INFANTS AND CHILDREN 6 MONTHS TO 5 YEARS (Example from Ghana) Key Points At 6 months, babies need more nutrients than breast milk alone can provide. They are also physically ready to eat foods. They can sit, hold their heads up and steady. They can swallow food more easily without spitting. Their stomachs have matured enough to digest foods properly. Babies sometimes reject food because the new taste and texture are different from the breast milk they are used to. Mothers need to take time to teach babies to eat new food by continuing to offer it to them. You will have to be patient and keep trying until the baby likes the food. It sometimes takes more than five times before the baby likes a food. Forcing your baby to eat might cause feeding problems such as the baby constantly rejecting food. Keeping your hands clean when preparing food or feeding your baby is essential. Wash your hands with soap and water to prevent diarrhoea-causing germs to get to your baby. Babies at this age often put their hands in their mouths. Washing their hands with soap and water helps them stay healthy. Babies should be fed from their own bowls. Dont give leftovers to the baby. Cooked foods should not be saved from one day to the next unless they are refrigerated. Foods should always be reheated to boiling and cooled before serving. Cooked food should not be given to the baby after two days in the refrigerator. Meeting Your Babys Food Needs Starting at 6 Months At 6 months, breast milk alone is not enough for the health and growth of your baby. Babies like a variety of foods, just like adults. There are many foods that babies like, such as Koko, rice, corn-soy blend (CSB), beans, yams and sweet potatoes. A small spoon makes it easier for a child to learn how to swallow food. As a baby gets older, the thickness of foods should increase. Thicker foods mean the baby will get more nutrients in each spoonful and feeding will take less time for you. Your baby has a small stomach. When food is thin and watery, they are getting water but less of the nutrients they need. Frequent breastfeeding continues to provide protection from disease and nourishment to your baby. Helping Your Baby to Grow Strong From 6 months on, babies need more than one type of food at each feeding to maintain their health and grow well. Fats/oil should be added to each meal. Any fat you have at home is OK for the baby. A small amount such as 1 teaspoonful of fat/oil is packed with energy. Babies accept fats easily at 6 months. Beans, fish, eggs, fish powder and meats help babies grow. Babies who eat those one-to-two times per day have good blood and are protected from illness. All mothers and/or caregivers are concerned about the cost of feeding their family, but luckily babies only need a small amount of animal protein. As part of a feeding, include a matchbox-size amount (or at least one tablespoonful) of mashed or chopped meat, egg or fish every other day to help your baby grow. The same amount of mashed beans, ground nuts or fish powder is needed on the days you dont give animal protein. Remember that frequent breastfeeding is still very important for your baby Vegetables and Fruits: Protecting Your Baby From Illness From 6 months on, babies need more than one type of food at each feeding to maintain their health and grow well. Many families think that fruits are not good for babies because they cause diarrhoea. This is not true. Babies need small quantities of fruits at a time, and the fruits should be washed very well. Many fruits contain nutrients that are essential for good health. In fact they protect babies from getting sick. Fruits that are orange like mangoes or pawpaw are especially high in needed vitamins. They are also plentiful and inexpensive. Babies love the sweet taste of fruits. Vegetables also add variety, vitamins and minerals to your babys meals. Cooked greens, pumpkins, squash or orange sweet potato will give important vitamins. Babies need fruits one-to-two times each day and also need vegetables one-to-two times per day. Frequent breastfeeding is still very important for your baby. How Much and How Often? 6 Months of Age One soup ladle of porridge at a meal Baby should be fed two times each day Frequent breastfeeding day and night 7-8 Months of Age Babies at this stage have learned about eating and can start to eat more at each meal and eat more frequently. Baby should eat three times per day. Each meal should contain the following: 1 soup ladle of a thick porridge with 1 teaspoon of oil/groundnut paste and fish powder/egg/soya bean powder or soup ladle of staple (e.g., yam, rice) and 1 stew ladle of stew/thick soup containing 1 tablespoon of mashed fish, meat or beans, And 2 tablespoon of mashed fruits or vegetables Frequent breastfeeding day and night. 9 Months to 1 Year of Age Most babies have some teeth and like to start chewing. Baby still needs to be fed three times a day but now also needs a snack. At least one snack each day is important for babies at this age. Snacks should be chosen wisely so they are not too sweet. Fruits, buttered bread, doughnuts are good choices of snacks. Babies eat better if a variety of foods are fed to them each day. The amount increases to: 2 soup ladles of a thick porridge with 1 teaspoon of oil/groundnut paste and fish powder/egg/soya bean powder or 1 soup ladle of staple (e.g., yam, rice) and 1 stew ladle of stew/thick soup containing 1 tablespoon of mashed fish, meat or beans, And 2 tablespoon of mashed fruits or vegetables Frequent breastfeeding is still very important for your baby. Annex 20. Emotional and Physical Stimulation Children with severe acute malnutrition (SAM) have delayed mental and behavioural development, which, if not treated, can become the most serious long-term consequences of malnutrition. Emotional and physical stimulation through play activities that start during rehabilitation and continue after discharge can substantially reduce the risk of permanent mental retardation and emotional impairment. Care must be taken to avoid sensory deprivation. It is essential that the caregiver be encouraged to feed, hold and play with the child as much as possible. STIMULATING ENVIRONMENT Inpatient and outpatient care activities should be carried out in a stimulating environment. For inpatient care, treatment should be carried out in brightly coloured rooms with decorations that interest children. The atmosphere should be relaxed, cheerful and welcoming. Toys should always be available for the recovering child to play with. The toys should be safe, washable and appropriate for the childs age and level of development. Inexpensive toys made out of simple materials such as cardboard boxes, plastic bottles and similar materials are best because caregivers can copy them. PLAY ACTIVITIES Malnourished children need interaction with other children during rehabilitation. For inpatient treatment after the initial phase of treatment, the child should spend prolonged periods playing with other children. These activities do not increase the risk of cross-infection appreciably and the benefit for the child is substantial. Community outreach workers (e.g., community health workers, volunteers) can also develop play activities in the community that can keep children in the outpatient care active. Activities should be selected to develop both motor and language skills, and new activities and materials should be introduced regularly. PHYSICAL ACTIVITIES Physical activities promote the development of essential motor skills and can also enhance growth during rehabilitation. For children who cannot move, passive limb movements and splashing in a warm bath are helpful. For other children, play should include such activities as rolling on a mattress, walking, and tossing and chasing a ball. The duration and intensity of physical activities should increase as the childs nutritional and general health improves. TOYS  Annex 21. Failure to Respond to Treatment in Inpatient Care Some children undergoing inpatient care might fail to respond to treatment or exhibit deterioration in condition at different stages of the treatment. Criteria for defining failure to respond to treatment are listed in Table 1. Failure to achieve initial improvement at the expected rate is termed primary failure to respond to treatment. This can be attributed to unrecognised infection or drug-resistant infections such as bacterial (tuberculosis [TB]), viral (measles, hepatitis B, HIV) or parasitic (malaria) infections. Deterioration in a childs condition after a satisfactory response has been established is termed secondary failure to respond to treatment. This may be due to acute infection contracted during inpatient care, reactivation of infection as immune and inflammatory responses recover, or insufficiency in essential nutrients in the diet provided to the child. Table 1. Criteria for Failure to Respond to Treatment in Inpatient Care* CriteriaTime after AdmissionPrimary failure to respondFailure to regain appetite4 - 7 daysOedema is not reducing4 - 7 daysOedema still present10 daysFailure to gain at least 5 g/kg bodyweight10 daysSecondary failure to respondFailure to gain at least 5 g/kg bodyweight Static weightDuring inpatient rehabilitation phase: for 2 successive days for 3 successive days* Primary failure to respond means when the criteria has been noticed since admission and secondary failure to respond means when the child has shown improvement and then later deteriorates as described by the criteria. A child who is undergoing treatment for severe acute malnutrition (SAM) and meeting any of the above criteria should be diagnosed as failing to respond to treatment. When such a diagnosis is made, an extensive medical evaluation of the child must be carried out (medical history, physical examination and/or laboratory investigations of urine and stool samples). The overall management of these cases should be reviewed, e.g., evaluation of adherence to treatment protocol and availability of trained staff. Failure to respond to treatment should be recorded on the individual treatment chart, and the child should be scheduled to be seen by more senior and experienced staff. Furthermore, corrective measures should be taken to strengthen specific areas that need improvement in the practice of management of SAM while ensuring that treatment protocols are followed and that staff receives adequate supervision. CARE FOR CHILDREN WHO FAIL TO RESPOND TO TREATMENT When a child shows signs of failure to respond to treatment, the causal factors contributing to this situation should be thoroughly investigated, and the child should be treated according to the recommendations in these guidelines. The child that fails to respond should receive a thorough medical examination. The following laboratory investigations are recommended: Urine analysis for pus cells and culture Blood screening and culture Screening for TB Stool test for trophozoites and cysts of Giardia HIV test according to the national guidance Malaria screening Hepatitis screening Primary Failure to Respond Every child with unexplained primary failure to respond should have a detailed medical history and examination performed. In particular, the child should be assessed carefully for infection as follows: Examine the child carefully. Measure the temperature, pulse rate and respiration rate. Where appropriate, examine urine for pus cells and culture blood. Examine and culture sputum or tracheal aspirate for TB; examine the fundi for retinal tuberculosis; do a chest x-ray. Examine stool for blood; look for trophozoites or cysts of giardia; culture stool for bacterial pathogens. Test for HIV, hepatitis and malaria. Culture and examine the cerebrospinal fluid (CSF). Secondary Failure to Respond Secondary failure to respond to treatment is a deterioration/regression in condition after having progressed satisfactorily to the rehabilitation phase with a good appetite and weight gain. It is usually due to: Inhalation of diet into the lungs. Children with SAM often have poor neuromuscular coordination between the muscles of the throat and the oesophagus. It is quite common for children to inhale food into their lungs during recovery if they are: 1) force-fed, particularly with a spoon or pinching of the nose; 2) laid down on their back to eat, and 3) given liquid diets. Inhalation of part of the diet is a common cause of pneumonia in all malnourished patients. Patients should be closely observed whilst they are being fed by the caregiver to ensure that the correct feeding technique is used. One of the advantages of ready-to-use therapeutic food (RUTF) is that it is much less likely to be force-fed and inhaled. An acute infection that has been contracted in the health facility from another patient (called a nosocomial infection) or at home from a visitor or household member. At times, as the immune and inflammatory system recovers, there appears to be a reactivation of infection during recovery; acute onset of malaria and TB (e.g., sudden enlargement of a cervical abscess or development of a sinus) could occur several days or weeks after starting a therapeutic diet. A limiting nutrient in the body that has been consumed by the rapid growth and is not being supplied in adequate amounts by the diet. This is very uncommon with modern diets (F100 and RUTF) but could occur with home-made diets or with the introduction of other foods. Frequently, introduction of the family diet slows a severely malnourished childs rate of recovery. The same can occur at home when the child is given family food or traditional complementary foods that are inadequate in Type 1 and Type 2 nutrients. ACTION REQUIRED WHEN A CHILD FAILS TO RESPOND TO TREATMENT Keep accurate records of all children who fail to respond to the treatment and of those who died. These records should include, at a minimum, the childs age, sex, date of admission, mid-upper arm circumference (MUAC), weight-for-height (WFH; or length) on admission, principal diagnosis, treatment and, where applicable, date, time and apparent cause of death. Always systematically examine the common causes of failure to respond and death, and identify areas where case management practices should be improved to rectify the problems. If these actions are not immediately successful, then an external evaluation by someone experienced with inpatient care of SAM should be conducted. An investigation into the organisation and application of the protocol for treatment should be carried out as part of the evaluation. Review the supervision of staff with refresher training if necessary. Re-calibrate scales (and height/length boards). BOX 1. EXAMPLES OF FREQUENT CAUSES OF FAILURE TO RESPOND TO TREATMENT IN INPATIENT CARE Problems related to the health facility: Poor environment for malnourished children Lack of adherence to treatment protocols for SAM Failure to treat malnourished children in a separate area Failure to complete the individual treatment card correctly resulting in gaps in data for monitoring the childs progress Insufficient staff Inadequately trained staff Inadequate supervision and constant rotation of staff in treatment facility Inaccurate weighing machines Food prepared or given incorrectly Problems related to the caregiver: Inappropriate care and feeding practices Uncooperative caregiver Caregiver overwhelmed with other work and responsibilities Problems related to the individual child: Insufficient feeds taken Sharing within family Vitamin and mineral deficiencies Malabsorption of food Psychological trauma (particularly in refugee situations and families living with HIV/AIDS) Rumination Infection, especially diarrhoea (amaebiasis, giardiasis, dysentery), pneumonia, TB, urinary infection/otitis media, malaria, HIV/AIDS, schistosomiasis, Kalazar/Leishmaniasis, hepatitis/cirrhosis Other serious underlying disease: congenital abnormalities (e.g., Downs syndrome), neurological damage (e.g., cerebral palsy), errors of metabolism  Annex 22. Community Assessment Questionnaire and Tools (EXAMPLES) COMMUNITY ASSESSMENT QUESTIONNAIRE The following topics and questions should be reviewed and adapted and next explored in a community assessment for CMAM: Topic One: Understanding Community Knowledge, Beliefs and Practices in Relation to Childhood Acute Malnutrition and Ill Health 1. Defining acute malnutrition What are the different terms used to describe acute malnutrition locally? Is there a perceived difference between acute malnutrition and general illness? 2. Signs of acute malnutrition What signs are locally associated with acute malnutrition? 3. Causes of acute malnutrition What are the locally-perceived causes of acute malnutrition? Note: There may be many perceived causes of malnutrition. Probe for awareness about the different causes of malnutrition including food, health and care, and cultural beliefs and practices in the community. 4. Treatment of acute malnutrition Note: In some areas treatment for acute malnutrition will be available through the national health system. Where this is the case, indicate which services are available and how far away these services are (distance and/or time required to travel there). How has the community traditionally dealt with acute malnutrition? Are home remedies with herbs used? If so, which herbs are used? Are traditional healers used? If so, which traditional healing practices are carried out? Has the use of home remedies or traditional healers changed in recent years? Was there an increase or decrease in their use? Why? Where conventional treatment is available through the health facilities, how does the community perceive these services? Is it happy to use the services? Do caregivers continue to use traditional healers while attending conventional treatment? 5. Treatment of sick children How does the community generally deal with a child who is sick? Are home remedies used? If so, which home remedies? Which services do caregivers take the children to for treatment: Ministry of Health, NGO or private clinic, or traditional healers? Are traditional treatments sought and administered before children are taken to a health facility? What are the key factors that influence the decision on where to take a child for treatment? 6. Infant and young child feeding (IYCF) Do most mothers breastfeed their babies under 6 months of age? At what age do mothers start to give additional liquids to infants (in addition to breastmilk)? At what age do mothers start to give complementary soft foods? What do they give? How many times per day would a mother feed a 12 month old infant? What is it fed? Topic Two: Understanding Community Systems, Structures and Organisation 1. Community organisation Explore the existence and level of activity of the various community groups in the district, and particularly those which focus on health and women. This includes groups created by communities themselves and groups with external support from a nongovernmental organization (NGO) and/or the government. Investigate if and how these various groups link together/coordinate activities. 2. Community outreach workers Explore the various health and nutrition community outreach workers and volunteer networks currently active in the area - the respective roles and responsibilities - which facilities these outreach workers and volunteers are attached to and the geographical coverage of the various cadres/networks within the area. (Includes nutrition educators, primary health acre cadres, vaccinators, community midwives, health extension workers, volunteers supported by any other agencies). Investigate commitment from unpaid volunteers in terms of hours worked per week / month 3. Formal and informal communication in the district Explore the usual methods of disseminating information to the community in the district, including the official methods (e.g., community meetings, through local leaders, local radio) and more informal methods (e.g., groups getting together on market day). Explore the perceived relative effectiveness of the various channels. 4. Options for supporting community participation and outreach activity for CMAM Explore perceptions of the key individuals and groups to involve in community participation and outreach activities. Gather suggestions on the most appropriate groups and networks to carry out outreach activity for CMAM. COMMUNITY ASSESSMENT TOOLS 1. Geographic community map Plot the presence of NGOs, community-based organizations (CBOs), community health committees and community volunteer networks on a geographic representation of the catchment area. Add geographic and demographic information and community structures (e.g., road, river, canyon, marketplace, mosque, health facility, water source). Represent the information on a hand drawn map on, for example, a flip chart. 2. Matrix of community actors and their initiatives, target population and coverage List NGOs, CBOs, community committees and community volunteer networks by community and/or assessment area. List the various community actors with their initiatives and/or activities, target population and coverage. 3. Strengths, weaknesses, opportunities and threats (SWOT) analysis for community participation and outreach for CMAM Conduct a SWOT analysis. Plot into a matrix the identified strengths and weaknesses of the current situation and the identified opportunities and threats for future community participation and outreach strategies and activities for CMAM. 4. Matrix of key perceptions and practices on health and nutrition List key perceptions and practices impacting health and nutritional status and implications for community participation and outreach strategies and activities for CMAM. Identify potential ways to appropriately address the identified key issues. 5. Matrix of potential community outreach workers for CMAM List community outreach workers, including various extension workers and volunteers, with potential for involvement in community outreach for CMAM. Identify strengths and weaknesses of involving these actors in community outreach for CMAM. 6. Matrix of community actors selected for community participation and outreach for CMAM List the various community actors that are identified to be used for community participation and outreach activities and coordination/supervision. Outline their respective responsibilities and specific functions at start up and during the implementation phase. Annex 23. Referral Slip Community Screening Child nameFamily nameName of mother/caregiverPlace of originReferral health facilityDate of community outreachBilateral pitting oedemaYes NoMUACmmOther findingsName of community outreach workerSignature Annex 24. Home Visit Record Form Reason for Home Visit: AbsentY / NDefaultY / NDeadY / NOtherRegistration No.DateSiteCommunityDistrictChilds nameAgeSexFamily nameName of caregiverAddressDate of visitFindingsOutreach Workers NameSignature Annex 25. Checklist for Home Visits (Example) DistrictName of Community Outreach WorkerDate of VisitName of Child  Note: If problems are identified, please list any health education or advice given in the space below or on the other side of the page. Return this information to the health facility. FeedingIs the ration of RUTF present in the home? YesNo If not, where is the ration? Is the available RUTF enough to last until the next Outpatient Care session?YesNoIs the RUTF being shared or eaten only by the sick child?SharedSick child onlyYesterday, did the sick child eat food other than RUTF?YesNo If yes, what type of food?Yesterday, how often did the child receive breast milk? (for children < 2 years)Yesterday, how many times did the sick child receive RUTF to eat?Did someone help or encourage the sick child to eat?YesNoWhat does the caregiver do if the sick child does not want to eat?Is clean water available? YesNoIs water given to the child when eating RUTF?YesNoCaringAre both parents alive and healthy?Who cares for the sick child during the day?Is the sick child clean?YesNoHealth and HygieneWhat is the households main source of water?Is there soap for washing in the house?YesNoDo the caregiver and child wash hands and face before the child is fed?YesNoIs food/RUTF covered and free from flies?YesNoWhat action does the caregiver take when the child has diarrhoea?Food SecurityDoes the household currently have food available?YesNoWhat is the most important source of income for the household?COMMENTS:  Annex 26. Community Outreach Reporting Sheet District NameState/Region NameReporting PeriodDateSupervisor/coordinator (name and position)Catchment AreaNumber of Children Under 5Expected Number or Children Under 5 with SAMNumber of CMAM Outpatient Sites Number of CMAM Inpatient Sites Number of communities in catchment area Key Indicators: Human resources: Number of community outreach workers MOH staff Number of community outreach volunteers Training: Number of community outreach workers including volunteers trained and active Number of community representatives oriented Community mobilization: Number of communities targeted and involved Number of communities meetings Community outreach: Number of community screening sessions conducted Number of children with SAM identified and referred for treatment Number of community home visits for problem cases Number of community health and nutrition education sessions held Coverage of CMAMReasons for absentees and defaultingReasons for non-response to treatmentCauses of deathBarriers to accessReasons Why Areas Are Not CoveredSuccess StoriesIdentified ProblemsPlanned Activities Annex 27. Inpatient Care Treatment Card  Name: ______________________ Male/Female Date of Birth/Age:__________ Date of Admission:________ Time of Admission:_________ ID Nr:_________ INITIAL MANAGEMENT Comments on pre-referral and/or emergency treatment already given: SIGNS OF MALNUTRITION SIGNS OF SHOCK None Lethargic/unconscious Cold hand Slow capillary refill (> 3 seconds) Weak/fast pulseSevere wasting? Yes No Bilateral Pitting Oedema? 0 + ++ +++If lethargic or unconscious, plus cold hand, plus either slow capillary refill or weak/fast pulse, give oxygen. Give IV glucose as described under Blood Glucose (left). Then give IV fluids: Amount IV fluids per hour: 15 ml x ____ kg (childs weight) = __________mlDermatosis? 0 + ++ +++ (raw skin, fissures)Weight (kg): Height/length (cm):WFH z-score: MUAC (mm): Start:Monitor every 10 minutes*2nd hrMonitor every 10 minutesTEMPERATURE: oC rectal axillary If rectal < 35.5o C, or axillary <35o C, actively warm child. Check temperatures every 30 minutes.Time*Resp. rate*BLOOD GLUCOSE (mmol/l): If no test, treat as if hypoglycaemia If <3mmol/l and alert, give 50 ml bolus of 10% glucose or sucrose (oral or NG). If <3 mmol/l and lethargic, unconscious, or convulsing, give sterile 10% glucose IV: 5 ml x ___kg (childs wt) = ___ml Then give 50 ml bolus NG. Time glucose given: Oral NG IVPulse rate**If respiratory and pulse rates are slower after 1 hour, repeat same amount IV fluids for 2nd hour; then alternate ReSoMal and F-75 for up to 10 hours as in right part of chart below. If no improvement on IV fluids, transfuse whole fresh blood. (See left, Haemoglobin.) HAEMOGLOBIN (Hb) (g/l): or Packed Cell Vol (PCV): Blood Type: If Hb <40 g/l or PCV<12%, transfuse 10 ml/kg whole fresh blood (or 5-7 ml/kg packed cells) slowly over 3 hours. Amount: Time started: Ended: DIARRHOEAWatery diarrhoea? Yes No Blood in stool? Yes No Vomiting? Yes No Number of days of diarrhoea: ___If diarrhoea, circle signs present: Skin pinch goes back slowly Lethargic Thirsty Restless/irritable Dry mouth/tongue No tears Sunken eyesEYE SIGNS: None Left Right MEASLES: Yes No Vaccination on admission:________ Bitots spots Pus/Inflammation Corneal clouding Corneal ulceration If ulceration, give vitamin A & Atropine immediately. Record on Daily Care page. If no ulceration, give Vitamin A on week four in treatment or upon discharge. Record on Comments/Outcome page.If diarrhoea and/or vomiting: For first 2 hours, give ReSoMal. Every 30 minutes, monitor and give:* ** 5 ml x ____ kg (childs wt) = ____ ml ReSoMal  For up to 10 hours, give ReSoMal and F-75 in alternate hours. Monitor every hour. Amount of ReSoMal to offer:* ** 5 to 10 ml x ____ kg (childs wt) = _____ to _____ ml ReSoMal Oral doses Vitamin A < 6 months*50 000 IUTimeStart*If eye signs/recent measles: on Day 1, 2, 15 6 12 months* **100 000 IUResp. rate**Single dose on week 4 or upon discharge >12 months* **200 000 IUPulse rateHIV test Yes No Date: Outcome: (If + give Cotrimoxazole)Passed urine? Y NFEEDING Begin feeding with F-75 as soon as possible. (If child is rehydrated, reweigh before determining amount to feed. New weight: ______ kg) Amount for 2-hourly feedings: ____ ml F-75* Time first fed: ______ * If hypoglycaemic, feed of this amount every half hour for first 2 hours; continue until blood glucose reaches 3 mmol/l. Record all feeds on 24-hour Food Intake ChartNumber stoolsNumber vomitsHydration signsAmount taken (ml)F-75F-75F-75F-75F-75* Stop ReSoMal if: Increase in pulse and resp. rates Jugular veins engorged Increase in oedema, e.g., puffy eyelids ** If bilateral pitting oedema, give ReSoMal 30 ml only after each watery stoolANTIBIOTICS (All received) Drug/RouteDose/Frequency/DurationTime of 1st DoseMALARIA TEST Type/Date/OutcomeAntimalarial: Dose/Frequency/DurationTime of 1st Dose  Name: ________________________________________________________ Page ____ of _____ DAILY CARE Week 1 Week 2 Week 3DAYS 123456789101112131415161718192021DateDaily weight (kg)Weight gain (g/kg bodyweight)Calculate if on RUTF/F100 Bilateral pitting oedema O + ++ +++Diarrhoea (D)/Vomit (V) O D VFEED PLAN: Type feed# daily feedsVolume to give per feedTotal volume taken (ml)NGT Y NBreastfeeding Y NAppetite test with RUTF F failed P passed ANTIBIOTICSList prescribed antibiotics in left column. Allow one row for each daily dose. Draw a box around days/times that each drug should be given. Initial when given.ANTIMALARIAL (note drug)FOLIC ACID (if not on RUTF) daily5mg1mg VITAMIN AGive day 1, 2 and 15 if child admitted with eye sign or recent measles. Else, give routinely single dose on week four or upon discharge unless evidence of dose in past monthNever give Vitamin A when child has bilateral pitting oedemaANTIHELMINTHIC (note drug)Give on week two, single doseIRON (if not on RUTF) 2 x daily Begin iron after 2 days on F100. Do not give when on RUTF.EYE INFECTIONS Tetracycline/ Chloramphenicol 1 drop 4 x daily After 7-10 days, when eye drops are no longer needed, shade boxes for eye dropsAtropine 1 drop 3 x daily Dermatosis 0 + ++ +++Ear problemsMouth or Throat problemsBathing, 1% permanganateOTHER Name: ________________________________________________________ Page ____ of _____ MONITORING RECORD Monitor respiratory rate, pulse rate, and temperature 4-hourly until after transition to RUTF or F-100 and patient is stable. Then monitoring may be less frequent (e.g., twice daily). RESPIRATORY RATEBreaths/ minutePULSE RATEBeats/ minuteTEMPERATURE39.539.038.538.037.537.036.536.035.535.034.5Date/time: Danger Signs: Watch for increasing pulse and respirations, fast or difficult breathing, sudden increase or decrease in temperature, rectal temperature below 35.5C, and other changes in condition (see Job Aid Danger Signs in Inpatient Care) Name: ________________________________________________________ Page ____ of _____ 24-HOUR FOOD INTAKE CHART Complete one chart for every 24-hour period. Admission weight (kg): ____________ Todays weight (kg): ________ Oedema: 0 + ++ +++ DATE:TYPE OF FEED: GIVE: _______ feeds of __________ml Timea. Amount offered (ml)b. Amount left in cup (ml)c. Amount taken orally (a b)d. Amount taken by NG, if needed (ml)e. Estimated amount vomited (ml)f. Watery diarrhoea (if present, yes)Column totalsc.d.e.Total yes:If child is ready for transition, test appetite. Appetite test: Failed PassedTotal volume taken over 24 hours = amount taken orally (c) + amount taken by NG (d) total amount vomited (e) = ____________ml Name: ________________________________________________________ Page ____ of _____ WEIGHT CHART Weight on admission: ______kg MUAC on admission: _____mm Height / length on admission:___________ cm Bilateral pitting oedema on admission: 0 + ++ +++ Weight free of oedema: _____kg Desired weight based on 15% weight change: ______ kg [Desired weight based on weight for height -1 z-score: _____kg] Weight at referral to outpatient care: ______ kg MUAC at referral to outpatient care: ______ mm Weight at discharge if treatment until full recovery in inpatient care ______ kg MUAC at discharge if treatment until full recovery in inpatient care ______ mmWeight (Use appropriate scale)DAY12345678910111213141516171819202122232425262728 Name: ________________________________________________________ Page ____ of _____ COMMENTS/OUTCOME COMMENTSSPECIAL DISCHARGE AND FOLLOW-UP INSTRUCTIONSTRAINING GIVEN TO PARENTS/ CAREGIVERSPATIENT OUTCOMEReferral to Outpatient CareDATECommentIMMUNIZATIONS Immunization card? Yes No Circle immunizations given. Initial and date by any given in Inpatient Care.In case of treatment in Inpatient Care Until Full Recovery or unexpected discharge, indicate outcome:Discharge based on 15% weight change (Discharged cured)Discharge weight e"15% weight gain: Y N MUAC: _________mm ImmunizationFirstSecondThirdBoosterEarly departure or defaulting (Discharged defaulted)BCGAt birthOptional: > 6 months//Non response to treatment (Discharged non-responded)PolioAt birth2 months3 months12 monthsReferral for non response to treatment or medical investigationDPT3 months4 months5 months12 monthsDeath (Discharged died) Number of days after admission (circle): < 24 1-3 days 4-7 days >7 days Approximate time of death: Day NightMeaslesUpon admissionUpon discharge Apparent cause(s) of death: Had child received IV fluids? Yes No Annex 28. Daily Feeds Chart DAILY FEEDS CHART DATE:________________________ WARD: _______________________ Name of ChildF-75F-100Number feedsAmount/ feed (ml)Total (ml)Number feedsAmount/ feed (ml)Total (ml)F-75 (total ml) needed for 24 hoursF-100 (total ml) needed for 24 hoursName of ChildRUTFNumber feedsPackets per dayRUTF total (sachets) for 24 hours  Annex 29. Outpatient Care Treatment Card FRONT ADMISSION INFORMATIONName Reg. No  / /Age (months)SexMale FemaleDate of admissionCommunity, DistrictTime to travel to siteHouse locationFather aliveYes/ NoMother aliveYes/ NoName of carerTotal number in householdTwin Yes/ NoAdmissionDirect from communityReferred from heath facilityReferred from inpatient careReadmission (relapse) Yes / NoAdmission anthropometryMUAC (mm)Weight (kg)Height (cm)WFH z-scoreAdmission criteriaBilateral pitting oedemaMUAC < 115 mm WFH < - 3 z-scoreOther, specifyTarget weight (kg) based on 15% weight gain (oedema free)Medical historyDiarrhoeaYesNo# Stools/day1-34-5>5VomitingYesNoPassing urineYesNoCoughYesNoIf oedema, since how long?AppetiteGoodPoorNoneBreastfeedingYesNoAdditional information Physical examinationAppetite TestPassedFailedRespiratory rate (# per min)<3030 3940 - 4950-5960 +Chest IndrawingYesNoTemperature (axillary) 0CPalmer PallorNormalPaleEyesNormalSunkenDischargeConjunctiva/ CorneaDehydration based on historyNoneModerateSevereEarsNormalDischargeMouth NormalSoresCandidaEnlarged lymph nodesNoneNeckAxillaGroinHands & feetNormalColdSkin changesNoneScabiesPeeling Ulcers / AbscessesDisabilityYesNoAdditional information Routine medicinesADMISSION: AmoxicillinDosage:Date:Malaria testPositive / Negative DateWEEK TWO: AntihelminthicYesNoMalaria symptomsYes NoWEEK FOUR: Measles vaccinationYesNoMalaria treatmentDrug/Dosage:Date:Vitamin AYesNoFully immunisedYes NoOther medicinesDrugDateDosageDrugDateDosage BACK MONITORING INFORMATIONWeeks in treatmentADM12345678910111213141516DateAnthropometry15% Target WeightBilateral Pitting Oedema (+ ++ +++)MUAC (mm)Weight (kg)Weight loss * (Y/N)*If no weight gain or losing weight do a home visit If below admission weight after 3 weeks* or weight loss for 2 weeks, or static weight for 3 weeks refer to inpatient careMedical historyDiarrhoea (# days)Vomiting (# days)Fever (# days)Cough (# days)Physical examinationTemperature (0C)Respiratory rate(# /min)Dehydrated (Y/N)Anaemia / palmer pallor (Y/N)Skin lesion (Y/N) Appetite check / feedingRUTF test Passed/FailedRUTF (# units given)Action / follow upACTION NEEDED (Y/N) (note below)Other medication (see card front)Name examinerOUTCOME ** ** OK=Continue Treatment A=Absent D=Defaulted (after 2 consecutive absences) R=Referral RR=Refused Referral C=Cured X=Died NR=Non-Recovered HV= Home Visit Action taken during home visit (include date)Name Community Outreach Worker  Annex 30. Referral Form for Inpatient Care/Outpatient Care NameDateTimeInitial treatment siteReferral treatment siteNameAgeWeightMUACTemperatureReason of ReferralTreatment Given before ReferralVaccinations Given before Referral (specify, date)Dose of Vitamin A Given before Referral (specify, date)Name or ResponsiblePositionSignature Annex 31. Site Tally Sheet SITE TALLY SHEET Community, District, State/RegionSITEOutpatient careInpatient careMONTHDate of weeksTotal start of week (A)TOTAL MONTHNew Cases SAM: Children 6-59 months (B1)Other New Cases SAM: Infant, child, adolescent, adult <6m and e"5years (B2)Old Cases SAM: Referred from Outpatient or Inpatient care; or Returned defaulter (C)TOTAL ADMISSIONS (D) (D=B1+B2+C) Discharged Cured (for children 6-59 months only) (E1)Discharged Died (for children 6-59 months only) (E2)Discharged Defaulted (for children 6-59 months only) (E3) Discharged Non-Recovered (for children 6-59 months only) (E4) TOTAL DISCHARGES (for children 6-59 months only) (E) (E= E1+E2+E3+E4)Referrals to Outpatient care or Inpatient care (F) TOTAL EXITS (G) (G= E+F) (+ add other age groups)Total end of week (A+D-G)GENDER NEW ADMISSIONS Children 6-59 months (B1) MALEFEMALEAnnex 32. Site Reporting Sheet MONTHLY SITE REPORT CMAM SITEIMPLEMENTED BYMOHOther: _______CommunityMONTH / YEARDistrictTYPEInpatient CareOutpatient CareState/RegionESTIMATED TARGET <5 y with SAM* (MUAC<115 mm) (WFH <-3 z-score) (Presence of Oedema)Total beginning of the month (A)New Cases (B)Old Cases (C) Referrals or Returned defaultersTOTAL ADMISSIONS (D) (B+C=D)Discharged children 6-59 months** (E) Referrals (F) TOTAL EXITS (G) (E+F=G)Total end of the month (H) (A+D-G=H)Children 6-59 m (B1)Other Infant, child, adolescent, adult <6m and e"5years (B2)Discharged CURED (E1)Discharged DIED (E2)Discharged DEFAULTED (E3)Discharged NON-RECOVERED (E4)Children 6-59 months% E1/E*100% E2/E*100% E3/E*100% E4/E*100TARGETS Sphere minimum standards>75%-<15%E1: Discharged Cured = met discharge criteria E2: Discharged Died = died while in treatment E3: Discharged Defaulted = absented for three consecutive visits in outpatient care/two days in inpatient care E4: Discharged Non-recovered = did not meet discharge criteria after four months in outpatient care/ after two months in inpatient care GENDER NEW ADMISSIONS children 6-59 months MALEFEMALE *Estimated target population under 5 = 20%, using the 2008 Census data; Estimated target population under 5 with SAM, expressed in numbers (WFH <-3 z score or MUAC<115 mm, and bilateral pitting oedema), based on latest survey data or admission data. ** Fill in a separate report for other age groups if a considerable number of cases from other age group are being admitted for treatment. Annex 33. Monthly District and State/Region Reporting Sheet MONTHLY REPORT CMAM (Sites Combined)Health facilitiesIMPLEMENTING PARTNER(S)DISTRICTNUMBER OF OUTPATIENT CARE SITESSTATE/REGIONNUMBER OF INPATIENT CARE SITESREPORTING PERIODNUMBER OF COMMUNITIESESTIMATED TARGET <5 y with SAM* (MUAC<115 mm) (WFH <-3 z-score) (Presence of Oedema) Total beginning of the period (A)New Cases (B)TOTAL ADMISSIONS (B)Discharged children 6-59 months** (E)TOTAL DISCHARGED (E)Total end of the month (H) (A+B-E=H)Children 6-59 m (B1)Other Infant, child, adolescent, adult <6m and e"5years (B2)Discharged CURED (E1)Discharged DIED (E2)Discharged DEFAULTED (E3)Discharged NON-RECOVERED (E4)Children 6-59 months% E1/E*100% E2/E*100% E3/E*100% E4/E*100TARGETS Sphere minimum standards>75%<10%<15%E1: Discharged Cured = met discharge criteria E2: Discharged Died = died while in treatment E3: Discharged Defaulted = absented for three consecutive visits in outpatient care/two days in inpatient care E4: Discharged Non-recovered = did not meet discharge criteria after four months in outpatient care/ after two months in inpatient care GENDER NEW ADMISSIONS children 6-59 months MALEFEMALE** Fill in a separate report for other age groups if a considerable number of cases from other age group are being admitted for treatment. Annex 34. Minimal Reporting Guidance for CMAM (EXAMPLE) Minimal Reporting Guidance for CMAM Introduction Author of report Date and period of reporting Geographical catchment area and population Name of health facilities with outpatient care and/or inpatient care Starting date of services Performance, Process and Output Indicators Number of new admissions Number of discharges Number of beneficiaries in treatment Number and percentage discharged cured, died, defaulted, non-recovered Number of referrals for non-response to treatment and/or medical complications Number of sites Number of staff trained (e.g., health managers, health care providers, community health workers [CHWs]) Number of volunteers trained Number of communities mobilized Causes of death Reasons of absentee, defaulting Barriers to access and utilization Some information may be collected monthly or periodically from sites if considered useful, calculated on all or a sample of treatment cards from discharged cured beneficiaries in a particular month Average length of stay (LOS) (expressed in days) Average daily weight gain (expressed in g/kg bodyweight/day) Referral rate Categories of admission: bilateral pitting oedema, severe wasting -MUAC or WFH z-score Figures Figure (graph) with trends of key performance and output indicators: Bars with new admissions, discharges, beneficiaries in treatment Lines for cured, died, defaulted and non-recovered rates Figure (graph) for monthly average length of stay (LOS) and average weight gain (AWG) per category of admission criteria Figure (pie chart) with distribution of admission criteria Figure (pie chart) with distribution of discharge categories Interpretation of Overall Progress Discuss strategy for capacity development and quality improvement Discuss performance Interpret findings on performance and coverage and any qualitative information that was obtained through community meetings, focus group discussions, etc.; then, triangulate the information. Discuss contextual information as appropriate, including context changes in relevant sectors such as food security, water and sanitation, health, insecurity that may have an influence on service operation or performance Discuss challenges, opportunities, lessons learned. Add success stories. Provide action plan for next month and support needed/planned to be given Annex 35. Checklists for Supportive Supervision (EXAMPLES, work in progress) COMMUNITY OUTREACH Checklist for Community Outreach at the community level Communities: __________________________________ Date: ____________ Community outreach worker(s)___________________ Referral Health facility: _______________________________________________ Name of Supervisor: ___________________________ Quality +++ Correct ++Needs improvement + Weak 0 Not done or done incorrectlyDiscussed Y/NCommentsCommunity workRegular contact and discussions with community leaders, groups and caregivers madeIEC on health and nutrition (see job aid) according to strategy givenBarriers to access and utilization of services discussed and identifiedScreeningActive screening and referral of cases with AMHome visitHome visits to absentees and defaulters from previous week (see job aid) doneHome visits for non-responders home visit (see job aid) doneBarriers to utilization of the services identifiedIEC on health and nutrition (see job aid) to caregivers during the home visit givenCaregiver to heath facility if appropriate referredCaregiver to other services if appropriate referredOutreach worker helpful, positive attitude with caregivers observedMonitoringJob aids for IEC and assessing problem cases used Outreach record filled and information with health facility sharedFeedback from health care provider on progress of the problem cases received Recommendations: Immediate action taken: Resources needed: Checklist for Home Visits Communities of Health Facility:_____________________________ Date:_________________ Quality 1 Done correctly 2 Done but needs work 3 Not done or done incorrectlyDiscussed Supervisor (Y/N)CommentAll absentees/defaults from previous week followed upHome visits form filled in correctly; information noted on RUTF ration cardAppropriate education (according to key messages) given to mothers/caregivers at homeMother/caregiver referred for additional care or services if appropriateTimely and appropriate referral to the clinician made for non-recovered casesOutreach worker returns home visit checklists or observations to health centreOutreach worker feedback provided on a timely basis (before the next outpatient care follow-up session)Outreach worker has helpful, positive attitude with mothers/caregivers OUTPATIENT CARE Checklist for Outpatient Care (Short version longer version available upon request) Health Facility: _________________________________ Date: __________________ District: ______________________________________ Region: __________________ Name of Heath Care providers present:___________________ ___________________________ Name of Supervisor ___________________________ (Add subheadings) Quality +++ Correct ++ Needs improvement + Weak 0 Not done/done incorrectlyDiscussed (Y/N)Comment Number of staff present Staff: Staff greet the mothers/caregivers and are friendly and helpful Registration numbers assigned correctly Registration numbers written on all documentation  Grade of bilateral pitting oedema measured accurately  Mid-upper arm circumference (MUAC) measured accurately  Weight measured accurately  Admission is according to correct criteria (spot check monitoring cards)Medical history recorded accurately  Physical examination performed accurately Childs appetite assessed using ready-to-use therapeutic food (RUTF) (on admission and at all follow-on visits)Routine medications given according to protocol and recorded accurately Amount of RUTF needed is correctly calculated  Appropriate education given to mothers of outpatient care beneficiaries Note topic: Follow-on medicines given according to protocol and recorded accurately Non-responders are identified according to the definition for follow-up Priorities for follow up home visits are discussed with a outreach worker if neededBeneficiaries discharged according to protocol Correct number of absentees/defaulters passed to outreach worker for follow upOutpatient care tally sheets, register and RUTF stock cards correctly completed (spot check)All absentees/defaulters from previous week followed upOutreach follow-up form filled in correctly and information noted on ration cardAppropriate education (according to education message sheet) given to mothers/caregivers at home Mother/caregiver referred for additional care or services if appropriate Timely and appropriate referral to the clinician made for non-responders Volunteer/outreach worker returns follow-up visit checklists or observations to health centre Volunteer/outreach worker feedback provided on a timely basis (before the next outpatient session) Volunteer/outreach worker has a helpful, positive attitude with caregivers  Recommendations: Immediate action taken: Resources needed: INPATIENT CARE Checklist for Inpatient Care - Ward Procedures Health Facility: _________________________________ Date: ___________________ District: ______________________________________ Region: __________________ Name of Heath Care providers present:___________________ ___________________________ Name of Supervisor ___________________________ OBSERVEYESNOCOMMENTSFeedingAre feeds prepared correctly with appropriate hygiene? Are correct feeds served in correct amounts?Are feeds given at the prescribed times, even on nights and weekends? (timings)Are children held and encouraged to eat (never left alone to feed)?Are children fed with a cup (never a bottle or other)?Is food intake (and vomiting/diarrhoea) recorded after each feed?Are leftovers recorded accurately and removed?Are amounts of F75 adapted with weight changes?Are milk amounts correctly measured and are leftovers discarded after use if no refrigeration?Warming Is the room kept between 25 and 30 degrees Celsius (to the extent possible)? Are blankets provided and children kept covered at night?Are safe measures used for rewarming children?Are temperatures taken and recorded correctly?Are adult beds provided and caregivers sleep with the children?WeighingAre scales functioning correctly?  Are scales standardised weekly? Are children weighed at about the same time each day?Are children weighed about one hour before a feed (to the extent possible)?Do staff adjust the scale to zero before weighing?Are children consistently weighed without clothes?Do staff correctly read weight to the nearest division of the scale?Do staff immediately record weights to the nearest division of the scale?Do staff immediately record weights on the childs Critical Care Pathway (CCP)?Are weights correctly plotted on the Weight Chart?Giving medications AND supplementsAre antibiotics given as prescribed (correct dose at correct time)? When antibiotics are given, do staff immediately make a notation on the CCP?Is folic acid given daily and recorded on the CCP?Is vitamin A given according to schedule? Is a multivitamin given daily and recorded on the CCP?After children on F100 for two days, given a correct dose of iron twice daily and recorded on the CCP?Ward environmentAre surroundings welcoming and cheerful?  Are mothers offered a place to sit, eat and sleep?Are mothers taught/encouraged to be involved in care?Are staff consistently courteous? As children recover, are they stimulated and encouraged to move and play? Recommendations: Immediate action taken: Resources needed: Checklist for Inpatient Care - Hygiene Health Facility: _________________________________ Date: ___________________ District: ______________________________________ Region: __________________ Name of Heath Care providers present:___________________ ____________________________ Name of Supervisor ___________________________ OBSERVEYESNOCOMMENTSHandwashingAre there working handwashing facilities in the ward? Do staff consistently wash hands thoroughly with soap? Are their nails clean? Do they wash hands before handling food? Do they wash hands between each patient?Mothers Cleanliness Do mothers have a place to bathe, and do they use it?Do mothers wash hands with soap after using the toilet or changing diapers? Do mothers wash hands before feeding children? Bedding and LaundryIs bedding changed every day or when soiled/wet? Are diapers, soiled towels and rags, etc. stored in a bag, then washed or disposed of properly? Is there a place for mothers to do laundry? Is laundry done in hot water? General MaintenanceAre floors swept? Is trash disposed of properly? Is the ward kept as free as possible of insects and rodents? Food StorageAre ingredients and food kept covered and stored at the proper temperature? Are leftovers discarded? DishwashingAre dishes washed after each meal? Are they washed in hot water with soap? ToysAre toys washable? Are toys washed regularly, and after each child uses them?  Recommendations: Immediate action taken: Resources needed: Checklist for Inpatient Care Clinical Care (See WHO 2002) Checklist for Inpatient Care - Feed Preparation Health Facility: _________________________________ Date: __________________ District: ______________________________________ Region: __________________ Name of Heath Care providers present:___________________ __________________________ Name of Supervisor ___________________________ (Adapt if commercial therapeutic formula milk is used) OBSERVEYESNOCOMMENTSAre ingredients for the recipe available? Is the correct recipe used for the ingredients that are available? Are ingredients stored appropriately and discarded at appropriate times? Are containers and utensils kept clean? Do kitchen staff (or those preparing feeds) wash hands with soap before preparing food?Are the recipes for F75 and F100 followed exactly? (If changes are made due to lack of ingredients, are these changes appropriate?) Are measurements made exactly with proper measuring utensils (e.g., correct scoops)?Are ingredients thoroughly mixed (and cooked, if necessary)? Is the appropriate amount of oil remixed in (i.e., not left stuck in the measuring container)?Is mineral mix added correctly? Is the correct amount of water added to make up a litre of formula? (Staff should not add a litre of water, but just enough to make a litre of formula) Is food served at an appropriate temperature? Is the food consistently mixed when served (i.e., oil is mixed in, not separated)? Are correct amounts put in the cup for each child in line with their specific treatment? Is leftover milk of the individual child discarded, measured and recorded, and discarded? Is leftover prepared milk discarded promptly? Other  Recommendations: Immediate action taken: Resources needed: Annex 36. Set-Up of Inpatient Care and Outpatient Care INPATIENT CARE Inpatient care is intended for the management of children 6-59 months with severe acute malnutrition (SAM) and poor appetite and/or medical complications and all infants under 6 months with SAM, as well as for those that cannot benefit from outpatient care due to distance, lack of caregivers or in the absence of RUTF. Inpatient care is established at the paediatric ward (or a specially assigned unit of the ward) at a hospital or health facility with bed capacity. In emergencies, a semi-permanent structure can be set up. In all cases, the health facility should have qualified and experienced staff, equipment and supplies, and a permanent supply of clean water for drinking, food preparation and sanitation. Experience shows that, on average, 10 to 20 percent of children with SAM will need stabilisation in inpatient care. This figure might be much higher at the start-up of an intervention if outpatient care is not covering all the areas of origin of beneficiaries or if early detection of cases is deficient (late presentation). Children with SAM and medical complications in the stabilisation phase are usually kept in a separate room from patients in the rehabilitation phase or other hospital patients. On average, patients in stabilisation stay for 3-10 days. Those who need to complete treatment in inpatient care stay an average of 30 days. Staff Needs Clinical Care Staff This includes senior nurses and junior nurses. A physician is recommended but is not always necessary. Only clinicians who are specifically trained in the management of SAM should treat these patients as many treatments normally given to children that are not malnourished could be dangerous for the malnourished child. Feeding Assistants Feeding assistants are in charge of weighing the child, supervising meals, interacting with caregivers, monitoring clinical warning signs and filling in most of the information on the patient's card. A ratio of one assistant per 10 patients is considered appropriate in emergency inpatient care health facilities. Other staff in this category could be in charge of the emotional and physical stimulation programme. Support Staff Cleaners and kitchen staff are vital to maintaining a tidy environment and preparing therapeutic milks and food for caregivers. In large centres, a person in charge of the logistics and transport will be necessary. Guardians, storekeepers and other ancillary staff might be needed depending on the context and size of the facility. Supervisors One supervisor is needed for each ward with inpatient care (usually, but not necessarily, a clinician). OUTPATIENT CARE Outpatient care is intended for children 6-59 months with SAM with good appetite and without medical complications and for children who have been referred from inpatient care after they have recovered appetite or their medical complications resolving. Outpatient care can be set up in a health facility or at health outreach sites, or with mobile teams. It is always advisable to have a store, a covered waiting area and a separate protected area for clinical assessment of patients even if the facility or site is in a provisional structure. Outpatients visit the health facility once a week or once every two weeks. The number of patients attending an outpatient care facility might vary from 10 to 20 per session to several hundreds. When too many children are attending on the same day, it might be appropriate to open new sites or increase the number of service days for existing facilities. Staff Needs A nurse or other health care provider (or several, depending on size) has sufficient skills to run outpatient care. Health care providers must be trained and able to identify danger signs and decide whether referral for inpatient care is necessary. They should be able to identify anorexia and assess childrens progress, calculate indicators for monitoring and evaluating patients (weight-for-height [WFH] z-score, weight gain, mid-upper arm circumference [MUAC]), fill in registration books and treatment cards, and manage stores and supplies of food and drugs. Where there are access problems or insufficient staff, mobile outpatient clinics could be used for a limited time. One mobile team can visit up to five sites a week, providing services once a week in each site. Annex 37. Checklist of Materials for Inpatient Care For guidance and information, consult the medical kits below and other supply and equipment lists. Note: Always check the health facilitys drug and equipment list to identify items that are needed in addition to their regular supply. MEDICAL KIT 1Inpatient Care, 400 children for 3 months or moreNAMENeeds (in unit)UnitORALFolic acid 5 mg5,000tabsAmoxicillin 250 mg30,000tabsChloramphenicol 250 mg4,000tabsCotrimoxazole 120 mg3,000tabsMebendazole 100 mg4,000tabsMetronidazole 250 mg2,000tabsNystatin 100,000 IU2,000tabsOral solution for rehydration 1 L / ReSoMal300sachetsParacetamol 100 mg2,000tabsQuinine 300 mg1,000tabsVitamin A 200 000 IU2,000gelVitamin A 50,000 IU1,000gelEXTERNAL USEBenzyl benzoate 90% 1L4LCetrimide 15% + chlorhexidine gluconate 1.5% 1 L5LTetracycline HCl 1% eye ointment 5 g300tubesBenzoic acid 6% + salicylic acid 3%50tube of 40 gGentian violet crystals 25 g12pot of 25 gZinc oxide 10% ointment20tube of 100 gPVP iodine 10% solution50vial of 200 mlNystatin ointment 100,000 IU/g 100tube of 30 gRENEWABLE EQUIPMENTTongue depressor, wood, 15*18 cm400piecesElastic bandage 7.5 cm x 5m20piecesNail brush10piecesGauze compresses 10*10 cm, sterile700piecesGauze compresses 10*10 cm, non sterile1,500piecesCotton 400 g10piecesExamination gloves, medium, disposable800piecesBlade for surgical knives, size 22100piecesBags for medicines2,000piecesAdhesive tape 5cmx 5cm20piecesThermometer100piecesGauze bandage200piecesAdhesive tape 2.5 cm16rolls MEDICAL KIT 2Inpatient care: 400 children for 3 months or more, in addition to kit 1NAMENeeds (in unit)UnitORALFerrous sulphate 200 mg15,000tabsINJECTABLESAmpicillin 1 g300vialsCeftriaxone 250 mg300ampsChloramphenicol 1 g400vialsDextrose 50%/20 ml25vialsDigoxine 0,25 mg/ml 2 ml vial100ampsWater for injectable preparations1,700ampsFurosemide 20 mg100ampsGentamicin 80 mg/2 ml400ampsQuinine 600 mg/2 ml100ampsDRIPSDextrose 5% in water, 500 ml without set40bagsRinger-lactate solution, 500 ml without set60bottlesRENEWABLE EQUIPMENTNeedle 18 g preparation1,000piecesNeedle 21 g IM1,200piecesNeedle 25 g subcutaneous1,000piecesUrine test strips (glucose, protein, PH)100piecesCatheter 22 g200piecesCatheter 24 g200piecesButterfly 21 g100piecesButterfly 25 g100piecesTourniquet4piecesHaemoglobin scale 557 tallquist booklet (250)1pieceInfusion giving set w/air inlet & needle100piecesBlood lancets200piecesSafety box6piecesSyringe, disposable, 0.5 ml200piecesSyringe, disposable, 2 ml1,000piecesSyringe, disposable, 5 ml1,000piecesSyringe, disposable, 10 ml400piecesSyringe, disposable, 20 ml600piecesFeeding tube ch. 5, disposable200piecesFeeding tube ch. 8, disposable400piecesFeeding tube ch. 10, disposable100pieces LABORATORY RESOURCES TB tests (x-ray, culture of sputum, Mantoux) Urinalysis Stool culture Blood culture Cerebrospinal fluid culture IMMUNIZATION RESOURCES Measles vaccines, plus other vaccines as per national expanded programme of immunisation (EPI) FEEDING EQUIPMENT AND SUPPLIES Therapeutic food: F75, F100 and RUTF CMV in case of no access to F75, F100, or ReSoMal Anthropometric equipment: Weighing scales for small children, Salter scale and Uniscale, MUAC tapes, height/length board Feeding cups and saucers Kitchen equipment for preparation of therapeutic milk: Dietary scales able to weigh to 5 g, whisks, large containers or buckets with lid, ladles, measuring cylinders, 1 and 2 litre jugs OTHER WARD EQUIPMENT AND SUPPLIES Adult beds with mattress Bed sheets Blankets or wraps Insecticide treated nets Safe toys Heater (if appropriate) Clean water supply Hygienic equipment for children: wash basins, potties, soap Kitchen equipment and food for caregivers Hygiene equipment for caregivers Method for safe disposal of trash Availability of toilets and bathroom FORMS AND CHECKISTS Renewable supplies, to keep topped off: Inpatient care treatment cards Daily feeds chart Road to Health card Referral form Site tally sheet Site reporting sheet Supervision checklist Ordering forms for supplies JOB AIDS National guidelines (manual) National guidelines for inpatient care brief version Laminated cards Anthropometric measurements: Weight, MUAC, height/length Admission and discharge criteria Appetite test Look-up table for WFH Guidance table target weight for discharge Routine medicines protocol Supplementary medicines protocols Look-up tables for F75 Look-up table for F100 Look-up tables for RUTF for inpatient care Danger signs in inpatient care Alternative recipes Entry and exit categories Health and nutrition education messages and ENA job aids Toys Others to develop and/or obtain: List of outpatient care sites with service days with contacts List of inpatient care sites with contacts Filing system for treatment cards Job descriptions Annex 38. Checklist of Materials for Outpatient Care The materials below suggest a start-up quantity for a period of three months, for 10 children being treated in Outpatient Care on average. The needs per site will then be adjusted according to current and projected case load. Note: Always check the health facilitys drug and equipment list to identify items that are needed in addition to their regular supply. MEDICINES AND DRESSING ItemQuantity (in units)UnitAmoxicillin 250 mg750tabsCotrimoxazole 120 mg75tabsMebendazole 100 mg100tabsParacheck30testACT50treatment doseMetronidazole 250 mg50tabsNystatin 100,000 IU50tabsParacetamol 100 mg50tabsVitamin A 100 000 IU50gelVitamin A 200 000 IU50gelBenzyl benzoate 90% 1L0.5LTetracycline HCl 1% eye ointment 5 g30tubesWitfields ointment30tubesGentian violet crystals 25 g1pot of 25 gZinc oxide 10% ointment1tube of 100 gNystatin ointment 100,000 IU/g 25tube of 30 gBetadine solution 2bottleCotton wool3RollsExamination gloves, medium, disposable30piecesBags for medicines50piecesThermometer10piecesGauze20packetsSmall bandage10piecesTape2piecesNormal saline for wounds 100 ml5piecesDressing scissors2pieces EQUIPMENT Item Quantity File for admission cards 1 per clinic Markers, pens 2 Clipboards 2 Stapler and box of staples 1 Pens 3 Scissors 1 pair Notebook 1 Calculator 1 Small clock with second hand 1 Bucket with lid 2 Soap for handwashing 3 bars Small bowl 1 Small jug 1 Hand towels 2 Water jug (with lid) 2 Plastic cups 20 Metal spoons 2 Teaspoons or medicine cups 6 Thermometer 5 Salter scale (25 kg) plus weighing pants 1 Uniscale 1 Height board 1 MUAC tape 10 Nail clippers 1 SUPPLIES TO KEEP IN STOCK Item Quantity Bags for carrying RUTF (if required) 50 Drinking water 1 jerry can Sugar to make 10% sugar solution 500 g Soap for distribution 20 bars RUTF Monthly calculation: Number of beneficiaries (A) Monthly sachet consumption per child 80 (or 20 sachets per child per week) Monthly sachet consumption per outpatient care site: A x 80 Monthly carton consumption: A x 80/150 (or 150 sachets in one carton) FORMS AND CHECKISTS Renewable supplies, keep topped off at 30: Outpatient care treatment card Road to Health card Referral form Home visit record Community outreach report Site tally sheet Site reporting sheet Ordering form for supplies Supervision checklist  JOB AIDS National guidelines (manual) National guidelines for outpatient care brief version Laminated cards: Anthropometric measurements: Weight, MUAC, height/length Admission and discharge criteria Look-up table for WFH Guidance table target weight for discharge Appetite test Routine medicines protocolSupplemental medicines protocol Look-up table for RUTF for outpatient care Action protocol Entry and exit categories Health and nutrition education messages and ENA job aids Toys Others to develop and/or obtain: List of outpatient care sites with service days List of communities in catchment area, with community leaders with contact List of community outreach workers per community with contact Filing system for treatment cards Job descriptions Annex 39. Forecasting Nutrition Product Needs FORECASTING THERAPEUTIC FOOD NEEDS IN INPATIENT CARE Assuming treatment lasts 10 days, 2 kilograms (kg) (5 packets) of dry F75 per child can be used for planning. This is equivalent to 6 kg per month of dry F75 for each paediatric bed dedicated for the management of complicated forms of severe malnutrition. Preparing this quantity of F75 locally (6 litres [L]) requires 19 grams (g) of mineral/vitamin mix (3 levelled scoops), 150 g of dried skim milk or 210 g of dried whole milk, 420 g of sugar, 162 g of vegetable oil and 210 g of cereal powder. Usually less than 5 percent of children admitted for SAM with medical complications (or less than 1 percent of all children with severe acute malnutrition [SAM]) will require F100 during the rehabilitation phase because they cannot eat ready-to-use therapeutic food (RUTF). For these children, 12 kg of F100 per child for the whole rehabilitation phase can be used for planning. RUTF is needed for a few days for every child in the transition phase and for all children in inpatient care (any phase) with appetite. FORECASTING THERAPEUTIC FOOD NEEDS IN OUTPATIENT CARE One treatment of a child with SAM based on +- 200 kcal/kg bodyweight/day of RUTF diet corresponds to approximately 30 to 40 g/kg bodyweight/day for 60 days. This is equivalent to 15 kg per treatment of a child with SAM, which can be used for planning purposes. Note that the total requirement of RUTF depends on the treatments duration and the childs weight at the beginning of treatment. Monthly calculation of RUTF needs in outpatient care (including loss and rounding): If number of beneficiaries in outpatient care is A Monthly sachet consumption per child in outpatient care is 80 (20 sachets per child per week) Monthly sachet consumption per outpatient care site is A x 80 Monthly carton consumption is A x 80/150 (150 sachets in one carton) Table 1. Estimated Quantities of Nutritional Products for Management of SAM (sites combined) Therapeutic foodWhen neededProportion of children with SAM needing the productDuration of treatmentQuantity needed to treat 1 child (kg)Quantity needed to treat 100 children with SAM (kg)F75Inpatient care (stabilisation phase)15%5-10 days2200 (x 15%)F100Inpatient care (rehabilitation phase)< 5%4-6 weeks12-151,500 (x 5%)RUTFOutpatient and inpatient care (transition/rehabilitation phase)> 95%6-8 weeks121,200 (x 95%)ReSoMalInpatient care20%0.08417 (x 20%)CMVInpatient careKeep always one pot in reserve as backup Estimating Case Load for CMAM In the absence of case load figures for services in similar locations (e.g., a similar neighbouring district or state), use the following steps to estimate SAM case load for planning purposes for a 12-month period: If Case load = prevalence (take # of prevalent cases at start of program) + incidence (add new # of cases expected over a 12-month period) and Incidence = prevalence / duration of illness (with duration of SAM illness estimated at 7.5 months or 7.5/12); therefore, incidence = prevalence x 12/7.5 or prevalence x 1.6 then Case load can be calculated by: prevalence + (prevalence x 1.6) Account for the expected service coverage: Assume a coverage of 70 percent and take into consideration any other necessary caveats, e.g., seasonality and stability of incidence, precision of survey prevalence estimates, indicators used for prevalence versus admission or a combination. Example, if planning for the treatment of SAM for the year 2016 in a population of 10,000 children under 5: If the estimated SAM prevalence rate from a survey done in December 2015 is 1.2 percent, on January 1, 2016, then there are 120 children with SAM. The number of new cases that will be expected to develop during the year, or 12-month incidence = prevalence/duration of disease = prevalence x 12/7.5. Incident cases are then expected to be 1.2 x 1.6 = 1.92 or 192 children Then, for a 12-month program we plan to treat the prevalent cases plus the incident cases over 12-month period, and thus plan for treating 120+192 = 312 children Next, we will account for the expected service coverage. Annex 40. Staff Needs, and Roles and Responsibilities STAFF NEEDS Inpatient Care Qualified clinician, at least one per shift for 24-hour care (nurse, medical assistant, physician, paediatrician) Nutrition assistant or assistant cook Support staff Liaison staff Outpatient Care Appoint in each health facility (and plan rotations if appropriate): A qualified health care provider (nurse or medical assistant) One assistant (if needed due to caseload) Community Outreach Each health facility should have established links with: A community outreach coordinator A team of community outreach workers (e.g., community health workers [CHWs] and/or volunteers), covering the communities in the health facilitys catchment area Training on community mobilisation, community screening and health and nutrition education should be provided to all health care providers (for orientation, supervision, coordination) and outreach workers (for implementation). An orientation is given at the start of the service followed by continuous training (e.g., refresher training, mentoring, feedback meetings). Notes: Recommended staff-to-bed ratio is 1:7. Experienced staff who are experts in the treatment of severe acute malnutrition (SAM) with medical complications, understand the needs of a child with SAM and are familiar with SAM services and aspects are essential for a well-functioning health facility. Loss of experienced staff must be avoided wherever possible. Disruption of ongoing services should not happen. ROLES AND RESPONSIBILITIES State/Region and District Health Manager and/or Nutrition Focal Point Resource mobilisation and allocation (human resources, infrastructure, supplies, transportation, training) Planning of services Supportive supervision Monitoring and reporting (M&R) on services Strengthening capacities of health care providers and community outreach workers State/Region and District Community Outreach Coordinator Community assessment and community mobilisation (e.g., community meetings) Training of community outreach workers Supportive supervision of community outreach workers M&R on community outreach Health Care Provider (Medical Officer, Nurse) in Inpatient Care Evaluation of childs medical condition and nutrition status (life saving procedures, anthropometry, medical history, physical examination, appetite test) Treatment of medical complications Treatment of SAM (prescription and administration of medicines and therapeutic food) Daily intensive care monitoring of danger signs Monitoring progress of children Update vaccination status Health and nutrition counselling Referral to outpatient care after stabilisation Referral to tertiary level in case of non-response to treatment M&R of service (site tally sheets and monthly reporting) Monitoring of equipment and supplies Linking with outpatient care services and community outreach workers Health Care Provider (Medical Assistant, Nurse) in Outpatient Care Evaluation of childs medical condition and nutrition status (triage, anthropometry, medical history, physical examination, appetite test) Admission Referral to inpatient care in case of medical complications upon admission, if developing danger signs during treatment or if non-response to treatment (action protocol) Treatment of SAM (prescription of medicines and ready-to-use therapeutic food [RUTF]) Monitoring progress of children Health and nutrition counselling Update vaccination status Organisation and supervision of outpatient care admission and follow-up sessions Discharge of children at end of treatment M&R of service (site tally sheets and monthly reporting) Monitoring of equipment and supplies Linking with community outreach workers Linking with other health, nutrition and livelihoods initiatives Community Outreach Workers (e.g., CHW) Community mobilisation Health and nutrition education based at health facility Community-based health and nutrition education and individual counselling Community screening and referral Home visits for problem cases Training of volunteers Volunteers Community mobilisation Community-based health and nutrition education and individual counselling Community screening and referral Home visits for problem cases Table 1. Outpatient Care Staff Detailed Responsibilities PositionResponsibilitiesHealth care providers Note: One health care provider should be responsible for overall supervision and case management at the site. Organise outpatient care setup and ensure smooth flow of patientsDo anthropometryInvestigate medical history through caregiver interviewCarry out initial physical examinationRecord admission information on treatment card Do appetite testRefer children for further medical care/inpatient care if necessaryPrescribe routine and additional medicines according to protocolPrescribe RUTF and advice (key messages)Review childs growth and health at each follow-up sessionIdentify non-responders for follow-up and further medical investigationIdentify absentees and defaulters for home visitLink mother/caregiver to the nearest outreach workerCouncil caregiver and give health and nutrition educationSupervise outpatient care staff and allocate dutiesManage logistics (stock management, transport for referrals, storage and supply of RUTF)Maintain good filing systemTrack children between and across servicesReview accuracy of treatment cards at the end of the outpatient care sessionFill site tally sheets and monthly reports and send to the District health officeMonitor performance indicators at the health facility levelCommunity health workers at the health facility and/or in the community Provide health and nutrition education sessions to caregivers in outpatient care Weigh, measure mid-upper arm circumference (MUAC) and check for oedema for all children attending outpatient care sessions Distribute RUTF rationDiscuss cases for home visits with assigned volunteer/outreach worker Review home visit checklists and report results to District health officeCoordinate regular meetings with volunteers/outreach workers to refresh training, share information, discuss performanceGive feedback to community leaders or committee on performance of SAM services and of volunteersInvolve influential community groups in case-finding (womens groups, community-based organisations [CBOs], religious groups)Community outreach worker Conduct community sensitisation meetings Do early case-finding in the community based on presence of bilateral pitting oedema and low MUAC Refer cases to the nearest outpatient care siteVisit absentee or defaulter at home and encourage them to return to outpatient care/inpatient careFollow-up with children who are not responding at home; investigate issues and offer adviceRecord home visits and report to outpatient care site on a timely basisGive monthly feedback to community leaders or health committees on issues such as number of beneficiaries and cure, default and death rates  Annex 41. List of Job Aids National MOH Nutrition Department Health and Nutrition policies, strategies and action plans CMAM guidelines National data repository for CMAM Capacity strengthening strategy and annual workplan for the CMAM support Terms of reference (TOR) of technical working groups Adapted job descriptions of MOH staff involved in CMAM District Health Department or State/Region Ministry of Health (MOH) [Planning for outpatient care, including list of materials and equipment, forecasting of supply needs, list of outpatient care sites, list of communities in catchment area, list of outreach workers] CMAM guidelines Packages of job aids and M&R tools List of sites with catchment area, service days State/Region data repository for the community-based management of SAM Report filing system Job descriptions Forms: Community assessment questionnaire and tools, referral slip community screening, home visit record, community outreach report, checklist home visits, inpatient care treatment card, daily feeds chart, outpatient care treatment card, home visit record, Road to Health card, referral form, site tally sheet, site reporting sheet, filing system, supportive supervision checklists, ordering forms for supplies. Inpatient Care [Planning for inpatient care, including list of materials and equipment, forecasting of supply and equipment needs, list of outpatient care sites, list of communities in catchment area, list of outreach workers] CMAM guidelines Anthropometric measurements Admission and discharge criteria Appetite test Look up table WFH Guidance table for target weight for discharge Routine medicines protocol Supplementary medicines protocols Danger signs in inpatient care Look-up tables for F75 Look-up table for F100 Look-up tables for RUTF for inpatient care Entry and exit categories Health and nutrition education messages (see also ENA job aids) Toys List of sites with catchment area, service day and name community outreach worker Job descriptions Forms: Inpatient care treatment card, daily feeds chart, Road to Health card, referral form, site tally sheet, site reporting sheet, filing system, supportive supervision checklist, ordering forms for supplies Outpatient Care [Planning for outpatient care, including list of materials and equipment, forecasting of supply needs, list of outpatient care sites, list of communities in catchment area, list of outreach workers] CMAM guidelines Anthropometric measurements Admission and discharge criteria Appetite test Look-up table for WFH Routine medicines protocol Drug dosages Look-up table for RUTF for outpatient care Action protocol Guidance table target weight for discharge Entry and exit categories Health and nutrition education messages (see also ENA job aids) Toys List of sites with catchment area, service day and name community outreach worker Job descriptions Forms: Outpatient care treatment card, Road to Health card, referral form, home visit record, site tally sheet, site reporting sheet, filing system, supportive supervision checklist, ordering forms for supplies Community Outreach [Planning for community assessment and outreach, including mapping, list of communities in catchment area, list of outreach workers, list of outpatient care sites] CMAM guidelines Messages for Community Outreach Anthropometric measurements Health and nutrition education messages Job descriptions Forms: Community assessment questionnaire and tools, referral slip community screening, home visit record, community outreach report, checklist home visits, supportive supervision checklist Appendix. Clinical Management of SAM with Medical Complications in Inpatient Care All children with severe acute malnutrition (SAM) with medical complications should be managed in in-patient care in a health facility with bed capacity and with staff trained in the special management of SAM with medical complications. These children should not be treated upon admission in the emergency ward but transferred to a special SAM ward where skilled health care providers will start life-saving treatment. The following paragraphs detail the diagnosis and treatment of the most common medical complications that occur in children with SAM. HYPOGLYCAEMIA Children with SAM can develop hypoglycaemia, though it is a very uncommon medical complication. All children who have travelled for long distances or have waited a long time for attention should be given sugar water as soon as they arrive (approximately 10 percent sugar solution: 10 g of sugar per 100 ml of water). Children that are at risk of hypothermia or septic shock should be given sugar water whether or not they have a low blood glucose level. A child who has taken the diet during the day will not develop hypoglycaemia overnight and does not need to be woken for night-time feeding. If the diet has not been taken during the day, the mother should give at least one feed during the night. Diagnosis of Hypoglycaemia There are often no clinical signs of hypoglycaemia. One sign that does occur in malnutrition is eye-lid retraction if a child sleeps with his/her eyes slightly open. Management of Hypoglycaemia If a child sleeps with his/her eyes slightly open, then he/she should be woken up and given sugar solution to drink. Children who are conscious and able to drink should be given about 50 ml (approximately 5 to 10 ml/kg bodyweight) of sugar water (about 10 percent ordinary sugar in potable water) or F75 (or F100) milk by mouth. The actual amount given is not critical. Children losing consciousness should be given 50 ml (or 5-10 ml/kg bodyweight) of sugar water by nasogastric tube (NGT) immediately. When consciousness is regained, give milk feed frequently. Unconscious children should be given sugar water by NGT. They should also be given glucose as a single intravenous (IV) injection (approximately 5 ml/kg bodyweight of a sterile 10 percent glucose solution). All children with SAM with suspected hypoglycaemia should be treated with second line antibiotics. The response to treatment is dramatic and rapid. If a very lethargic or unconscious child does not respond in this way, then there IS another cause giving rise to the clinical condition that has to be identified and treated. HYPOTHERMIA Children with SAM are highly susceptible to hypothermia (rectal temperature below 35.5C or axillary temperature below 35C). Diagnosis of Hypothermia Check the temperature of the room (it should be 28-32C). Check if the child sleeps with his/her caregiver. Check the temperature of the child: rectal temperature < 35.5C; axillary temperature < 35C. Management of Hypothermia Care should be taken not to bathe children with SAM on admission. Bathing should be done after the child has stabilised. Bathe children during the warmest part of the day using warm water. Drying of children should be done quickly and gently after washing. Use the kangaroo technique: put the naked child on the naked skin of the caregiver, put a hat on the child and wrap caregiver and child together, give hot drinks to the caregiver so her skin gets warmer (plain water, tea or any other hot drink). Monitor body temperature during re-warming. The room should be kept warm, especially at night (between 28-32C): a maximum-minimum thermometer should be on the wall in the stabilisation phase area to monitor the temperature. Treat for hypoglycaemia and give second-line antibiotic treatment. Note: The thermo-neutral temperature range of the room for children with SAM is 28-32C. This is often uncomfortably warm for the staff and caregivers who may adjust the room to suit themselves. Children with SAM should always sleep with their caregivers and not in traditional hospital child-cots/cages. There should be adequate blankets and a thick sleeping mat or adult bed. Most heat is lost through the head; hats should be worn by malnourished children. Windows and doors should be kept closed at night. DEHYDRATION Misdiagnosis and inappropriate treatment for dehydration is the most common cause of death for malnourished children. The appearance of a severely wasted child who is not dehydrated is similar to a normal child who is dehydrated; therefore an untrained clinician may easily misdiagnose dehydration in SAM. With SAM, the therapeutic window is narrow so that even dehydrated children can quickly go from having a depleted circulation to over-hydration with fluid overload and cardiac failure. Intravenous (IV) infusions are therefore rarely used in children with SAM. In malnourished children, both marasmus and to a greater extent kwashiorkor, there is a particular renal problem that makes the children sensitive to sodium overload. The standard rehydration protocol for a well-nourished dehydrated child should therefore not be used. Access to Rehydration Solution for Malnutrition (ReSoMal) should be restricted and must never be freely available for the caregivers to give to their children whenever they have a loose stool. Although a common practice, it is very dangerous to freely give ReSoMal or Oral Rehydration Solution (ORS) to these children. This can lead directly to heart failure, as well as failure to lose oedema, development of refeeding oedema, and failure to report and record significant problems while the diet and phase remains unchanged. If there is no dehydration, diarrhoea must not be treated with rehydration fluids as a means of preventing the onset of dehydration. This again can lead to over-hydration and heart failure. Dehydration in Children with Marasmus All the classical signs of dehydration (i.e., skin pinch test, sunken eyes) are unreliable in marasmic children and should therefore not be used to make the diagnosis of dehydration in these children. The skin of marasmic children normally lies in folds and is inelastic such that the skin pinch test is usually positive without there being any dehydration. Do NOT use the skin pinch test to diagnose dehydration in malnourished children. Eyes of marasmic children are normally sunken without there being any dehydration. Do NOT assume that children with SAM with sunken eyes have dehydration. The diagnosis of dehydration in marasmic children is therefore much more uncertain and difficult than in normal children. Incorrect and over-diagnosis is very common and treatment is often given inappropriately. It is good practice not to make a definitive diagnosis of dehydration: if you think the child is dehydrated then make a provisional diagnosis and observe the response to treatment before confirming the diagnosis. (See Box 1.) BOX 1. DIAGNOSIS OF DEHYDRATION IN THE MARASMIC CHILD The main diagnosis of dehydration in marasmic children comes from the history rather than from physical examination. There needs to be: A definite history of significant recent fluid loss - usually diarrhoea which is clearly watery (not just soft or containing mucus) and frequent with a sudden onset whose occurrence is within the past few hours or days. There should also be a history of a recent change in the childs appearance. If the eyes are sunken, the caregiver must confirm that the appearance of the eyes has changed to become sunken since the diarrhoea started. The child must not have any oedema. Children with persistent or chronic diarrhoea (without an acute watery exacerbation) are not dehydrated and do not need acute rehydration therapy. They have adapted over the weeks to their altered hydration state and should therefore not be rehydrated over a few hours or days.  Diagnosis of Shock with Dehydration in the Marasmic Child When there is definite dehydration diagnosed from both the history and examination and there is presence of a weak or absent radial or femoral pulse, cool or cold hands and feet (check with back of hand gently), or slow capillary refill (over three seconds), the child is going into shock. Severe shock occurs when, in addition to the above signs, there is also a decrease in the level of consciousness so that the child is semiconscious or cannot be aroused. Note: There are other causes of shock in the severely malnourished child. In particular: 1) toxic shock, 2) septic shock, 3) liver failure and 4) cardiogenic shock. Treatment of cardiogenic shock or liver failure based on the assumption that the child has shock due to dehydration is very dangerous and the treatment itself may then lead to death. Treatment of Dehydration in the Marasmic Child Whenever possible, a dehydrated child with SAM should be rehydrated orally. IV infusions are very dangerous and are not recommended unless there is severe shock with loss of consciousness from confirmed dehydration. The management of the rehydration process is based upon accurate measurements of weight (this is the best measurement of fluid balance). The weight measurements should be taken using an infant scale or, in the case of older children, a hanging scale to which a basin is attached with rope. The basin hangs close to the ground and is easily cleaned. The children should be weighed naked. (See Box 2.) Monitoring Rehydration in the Marasmic Child Before starting any rehydration therapy, do the following: Weigh the child Mark the edge of the liver and the costal margin on the skin with an indelible marker pen Record the respiration rate In addition, the following can be recorded on the treatment card if staff has the necessary skill: Record the heart sounds (presence or absence of gallop rhythm) Record the pulse rate on the treatment card BOX 2. REHYDRATION IN THE MARASMIC CHILD Rehydration of the child with SAM is managed entirely on the basis of the following: Weight changes Clinical signs of improvement Clinical signs of over-hydration  Fluid balance is measured at intervals by weighing the child. Give rehydration fluid until the weight deficit (measured or estimated) is corrected. Stop as soon as the child is rehydrated to the predetermined target rehydrated-weight. Additional fluid is not given to the malnourished child with a normal circulatory volume in order to prevent recurrence of dehydration. Normally much less ReSoMal is sufficient to restore adequate hydration in malnourished children than in normally nourished children (e.g., a total of 50 ml/kg bodyweight or 5 percent bodyweight). Begin rehydration therapy with a volume of 5 ml/kg bodyweight given at 30-minute intervals for the first two hours orally or by NGT or 2 percent bodyweight, and then adjust the volume of ReSoMal according to the weight changes observed. Weigh the child each hour and assess his/her liver size, respiration rate and pulse. After the rehydration therapy is completed usually no further treatment is given; however, for malnourished children aged 6-24 months, 30 ml of ReSoMal can be given for each watery stool that is lost. The standard instructions to give 50-100 ml for each stool should not be applied it is dangerous. As the child gains weight, during rehydration there should be a definite clinical improvement and the signs of dehydration should disappear; if there are no signs of improvement accompanying the weight gain then the initial diagnosis was wrong and rehydration therapy should be stopped. Make a major reassessment at two hours. If there is continued weight loss: Increase the rate of administration of ReSoMal by 10 ml/kg bodyweight/hour Formally reassess in one hour If there is no weight gain: Increase the rate of administration of ReSoMal by 5 ml/kg bodyweight/hour Formally reassess in one hour If there is weight gain and deterioration of the childs condition with the re-hydration therapy: The diagnosis of dehydration was definitely wrong. It must be noted that even senior clinicians also make mistakes in the diagnosis of dehydration in malnutrition. Stop the ReSoMal and commence the child on the F75 diet. If there is no improvement in the mood and look of the child or reversal of the clinical signs: The diagnosis of dehydration was probably wrong. Either change to F75 or alternate F75 and ReSoMal. If there is clinical improvement but there are still signs of dehydration: Continue with the treatment until the appropriate weight gain has been achieved. Either continue with ReSoMal alone, or F75 and ReSoMal can be alternated. If there is resolution of the signs of dehydration: Stop rehydration treatment and commence the child on F75 diet. Target Weight for Rehydration with Watery Diarrhoea in the Marasmic Child If the child has been under treatment for SAM and there is a known pre-diarrhoeal weight just before the diarrhoea starts: If there has been no weight loss with the diarrhoea, rehydration treatment should not be given. If there has been weight loss, the actual fluid loss is equal to the weight loss and the target rehydration-weight is the pre-diarrhoeal weight. Treatment should not be given to increase the weight beyond the pre-diarrhoeal weight. Prophylactic administration of ReSoMal to prevent recurrence of dehydration is not given. If the child is newly admitted, it is extremely difficult to judge the amount of fluid that has been lost in the child with marasmus. Because of the narrow therapeutic window and the danger of going from underhydration to overhydration, the estimated weight deficit should be very conservative. It is better and much less dangerous to slightly underestimate the amount of weight deficit than to overestimate the weight deficit. In practice, the weight loss is generally 2 to 5 percent of bodyweight. Do not attempt to increase bodyweight by more than 5 percent in conscious children. If there is weight gain of up to 5 percent of bodyweight with rehydration, the truly dehydrated child will show dramatic clinical improvement and be out of immediate danger from death due to dehydration; treatment can then be continued with F75. Breastfeeding should not be interrupted during rehydration. Begin to give F75 as soon as possible, orally or by NGT. ReSoMal and F75 can be given in alternate hours if there is still some dehydration and continuing diarrhoea. Introduction of F75 is usually achieved within two-to-three hours of starting rehydration. See figure 1. Treatment of Shock from Dehydration in the Marasmic Child If there is definite dehydration (e.g., a history of fluid loss, a change in the appearance of the eyes) and the child is semiconscious or unconscious AND has a rapid weak pulse AND has cold hands and feet, the child should be treated with IV fluids. The amounts given should be half or less of that used in normally-nourished children. Use one of the following solutions: Half-strength Darrows solution Ringer-Lactate with 5 percent dextrose Half-strength saline with 5 percent dextrose Management of Shock from Dehydration (See Figure 2) Give 15 ml/kg bodyweight IV over the first hour and reassess the child. If there is continued weight loss or the weight is stable, repeat the 15 ml/kg bodyweight IV over the next hour. Continue until there is weight gain with the infusion. (15 mg/kg bodyweight is 1.5 percent of bodyweight, so the expected weight gain after two hours is up to 3 percent of bodyweight.) If there is no improvement and the child has gained weight, then assume that the child has toxic, septic or cardiogenic shock or liver failure. Stop rehydration treatment. Search for other causes of loss of consciousness. As soon as the child regains consciousness or the pulse rate drops towards a normal level, stop the drip and treat the child orally or by NGT with 10 ml/kg bodyweight/hour of ReSoMal. Continue with the protocol (see second bullet above) for rehydration of the child orally using weight change as the main indicator of progress. There should never be a drip present in a malnourished child who is able to drink or is absorbing fluid adequately from an NGT. Figure 1. Rehydration in the Marasmic Child  Figure 2. Treatment of Dehydration in the Marasmic Child  Monitoring Rehydration in the Marasmic Child All rehydration (oral or IV therapy should be stopped immediately if any of the following are observed: The target weight for rehydration has been achieved (change to F75) The visible veins become full (change to F75) The development of oedema (over-hydration change to F75) The development of prominent neck veins* The neck veins engorge when the abdomen (liver) is pressed* An increase in the liver size by more than one centimetre (cm)* The development of tenderness over the liver* An increase in the respiration rate by five breaths per minute or more* The development of a grunting respiration (this is a noise on expiration not inspiration)* The development of crepitations in the lungs The development of a triple rhythm * If these signs develop, the child has fluid overload, an over-expanded circulation and is going into heart failure. Dehydration in Children with Kwashiorkor All children with oedema have increased total body water and sodium levels. In other words, they are over-hydrated. Oedematous children cannot be dehydrated, although they are frequently hypovolaemic. The hypovolaemia (relatively low circulating blood volume) is due to a dilatation of the blood vessels with a low cardiac output. Treatment of Dehydration in the Child with Kwashiorkor If a child with kwashiorkor has definite watery diarrhoea and the child is deteriorating clinically, then the fluid lost can be replaced on the basis of 30 ml of ReSoMal per watery stool. The treatment of hypovolaemia in kwashiorkor is the same as the treatment for septic shock. Hypernatraemic Dehydration Hypernatraemic dehydration is common in areas with a low relative humidity (very dry atmosphere), particularly if there is also a high temperature. It is caused by loss of water without loss of salt, leading to pure water deficiency. This is because water is lost through the skin and breath at a high rate under these conditions. If solutions high in sodium or other osmolyte that is not metabolised are given, then water will still be lost while leaving the osmotically-active solute in the body. Also, in areas where bottle feeding is common, mothers frequently over-concentrate infant formula; this can lead to hypernatraemic dehydration even in wet or cold climates and is lethal in hot and dry climates and seasons. The malnourished child is particularly at risk because he/she has a very low renal-concentrating ability and a high surface area relative to his/her body mass. During development of the high plasma osmolarity, there is a balancing increase in intra-cellular osmolytes to prevent water being drawn out of the cells. During treatment, if the extracellular fluid osmotic pressure is reduced too quickly leaving a high intracellular osmotic pressure, sudden cellular swelling occurs that can lead to swelling of the brain to a sufficient degree to give convulsions and death. Although hypernatraemia is difficult to treat safely, it is easy to prevent safely. Malnourished children, particularly those in dry and hot environments should have continuous access to sufficient water without a high ion content that requires renal excretion to fulfil their requirements for water. Diagnosis of Hypernatraemic Dehydration The first sign of hypernatraemic dehydration is a change in the texture and feel of the skin, which develops a plasticity similar to the feel of dough (flour and water mixed for bread making). The eyes can sink somewhat. The abdomen then frequently becomes flat and may progressively become sunken and wrinkled (so-called scaphoid abdomen or prune belly). The child may then develop a low-grade fever if there is insufficient water to evaporate to excrete the heat generated during normal metabolism. The child becomes progressively drowsy and then unconscious. Convulsions follow this stage, which leads to death if treatment for hypernatraemia is not instituted. The convulsions are not responsive to the normal anti-convulsants (e.g., phenoparbitone, diazepam). Failure to control convulsions with anti-convulsants may be the first indication of the underlying diagnosis. The diagnosis can be confirmed by finding an elevated serum sodium: normally hypernatraemia is diagnosed when the serum sodium is greater than 150 millimoles per litre (mmol/L). Treatment of Hypernatraemic Dehydration For insipient hypernatraemic dehydration a conscious, alert child who is only showing changes in the texture and feel of the skin breast milk is the best diet. This can be supplemented with up to about 10 ml/kg bodyweight/hour of water that should be given as a 10 percent sugar-water solution in sips over several hours until the thirst of the child is satisfied. At this early stage when impending water deficiency should be recognised and treated treatment is relatively safe. Treatment must be slow for developed hypernatraemic dehydration. If it is possible to measure serum sodium, aim to reduce the serum sodium concentration by about 12 mmol every 24 hours. Trying to correct the hypernatraemia quicker than this risks death from cerebral oedema. If it is not possible to measure the serum sodium, aim to correct hypernatraemic dehydration over at least 48 hours. The treatment should start slowly, and as the serum sodium approaches normality, the rate of repletion can increase. The textbook treatment of hypernatraemia is to slowly give normal saline either orally or intravenously. This is dangerous in the severely malnourished child and should not be used, as it is based upon the premise that the excess sodium given can be safely excreted by the kidneys, which is not the case in the severely malnourished child. Treatment progress is assessed by serial weighting of the child: First, put the child in a humid, thermoneutral (28 to 32C) environment. This is critical to prevent further water loss as well as hyperthermia if the humidity in the air is increased in a hot environment. Weigh the child on an accurate balance and record the weight. The objective of treatment is to put the child into a positive water balance of about 60 ml/kg/day, which is equivalent to 2.5 ml/kg bodyweight/hour of plain water. This amount should not be exceeded until the child is awake and alert. If the child is conscious or semi-conscious and there is no diarrhoea, put down a NGT and start 2.5 ml/kg bodyweight/hour of a 10 percent sugar-water solution. Do not give F75 at this stage, as it gives a renal solute load (mainly as potassium). Never give F100 or infant formulae. Reweigh the child every two hours. If the weight is static or there is continuing weight loss, recheck the environment to try to prevent on-going water losses then increase the amount of sugar-water intake to compensate for the ongoing weight loss (calculated as g/hour and increase the intake by this amount). If the weight is increasing, continue treatment until the child is awake and alert. If there is accompanying diarrhoea, give one-fifth the normal saline in 5 percent dextrose orally or by NGT. If the child is unconscious, the same volumes of fluid (5 percent dextrose if there is no diarrhoea and one-fifth normal saline in 5 percent dextrose if there is diarrhoea) can be given by IV infusion. There should be a peristaltic pump or accurate paediatric burette in order to ensure that that the rate of administration of fluid is not exceeded during treatment. When the child is awake and alert, recommence feeding with F75. SEPTIC (OR TOXIC) SHOCK Septic shock presents with some of the signs of true dehydration and also of cardiogenic shock; the differential diagnosis is often very difficult. Children that appear very ill may have septic shock, cardiogenic shock, liver failure, poisoning with traditional medicines, malaria, acute viral infection or other severe conditions. All very ill children should not be automatically diagnosed as having septic shock; the true reason for the condition should be sought. If this develops after admission to inpatient care, the treatment given to the child should be carefully reviewed to determine if the treatment is the cause of the clinical deterioration. Any unusual drugs should be stopped. Diagnosis of Septic Shock Diagnosis of developed septic shock requires that the signs of hypovolaemic shock be present. They include a fast weak pulse with: Cold peripheries Disturbed consciousness Absence of signs of heart failure Treatment of Septic Shock All children with signs of incipient or developed septic shock should immediately be: Given broad-spectrum antibiotics Second line and first line antibiotics should be given together For developed septic shock, consider third line antibiotics, antifungal treatment and anti-staphylococcal treatment Kept warm to prevent or treat hypothermia Given sugar-water by mouth or NGT as soon as the diagnosis is made (to prevent hypoglycaemia) Be physically disturbed as little as possible (e.g., no washing, no excess examination, no investigations in other departments) Never be transported to another facility the stress of transport leads to dramatic deterioration For Incipient (Early) Septic Shock Give the standard F75 therapeutic diet by NGT. For Developed Septic Shock If the child is unconscious because of poor brain perfusion, a slow IV infusion of one of the following can be given: Whole blood of 10 ml/kg bodyweight over at least three hours nothing should be given orally during the blood transfusion OR 10 ml/kg bodyweight/hour for two hours of one of the following (do not give if there is a possibility of cardiogenic shock): Half-strength Darrows solution with 5 percent glucose Ringers lactate solution with 5 percent glucose Half-normal (0.45 percent) saline with 5 percent glucose Monitoring Treatment of Septic Shock Monitor the child every 10 minutes for signs of deterioration, especially overhydration and heart failure, including: Increasing respiratory rate, development of grunting respiration Increasing liver size Vein engorgement As soon as the child improves (e.g., stronger radial pulse, regain of consciousness) stop all IV intake and continue with a F75 diet. If there are absent bowel sounds, gastric dilatation and intestinal splash with abdominal distension: Give first and second line antibiotic treatment by intramuscular (IM) injection. Consider adding third line antibiotics. Stop all other drugs that may be causing toxicity (such as metronidazole). Give a single IM injection of magnesium sulphate (2 ml of 50 percent solution). Pass a NGT and aspirate the contents of the stomach. Then irrigate the stomach with isotonic clear fluid (5 percent dextrose or 10 percent sucrose the solution does not need to be sterile). Do this by introducing 50 ml of solution into the stomach and then gently aspirating all the fluid back again. This should be repeated until the fluid that returns from the stomach is clear. Put 5 ml/kg bodyweight of sugar water (10 percent sucrose solution) into the stomach and leave it there for one hour. Aspirate the stomach and measure the volume that is retrieved. If the volume is less than the amount that was introduced then either a further dose of sugar water should be given or the fluid returned to the stomach. There is frequently gastric and oesophageal candidiasis. In this case, give oral nystatin suspension or fluconazole. Keep the child warm. If the childs level of consciousness is poor, given IV glucose: Do not put up a drip at this stage. Monitor the child carefully for six hours, without giving any other treatment Improvement is measured first by a change in intestinal function (i.e., decrease in the distension of the abdomen, visible peristalsis seen through the abdominal wall, return of bowel sounds, decreasing size of gastric aspirates) and secondly by improvement in the general condition of the child. If there is intestinal improvement, start to give small amounts of F75 by NGT (half the quantities given in the stabilisation phase look-up table subsequently adjust by the volumes of gastric aspirated). If there is no improvement after six hours: Consider putting up an IV drip. It is very important that the fluid given contains adequate amounts of potassium. Sterile potassium chloride (20 mmol/L) should be added to all solutions that do not contain potassium. If it is available, use one-fifth normal saline in 5 percent dextrose, otherwise use Ringer-Lactate in 5 percent dextrose or half-strength saline in 5 percent dextrose. The drip should be run VERY SLOWLY the amount of fluid that is given should not be more than 2 to 4 ml/kg bodyweight/hour. Start to give the first and second line antibiotics intravenously. When the gastric aspirates decrease such that one half of the fluid given to the stomach is absorbed, discontinue the IV treatment and continue with oral treatment only. HEART FAILURE Diagnosis of Heart Failure Heart failure should be diagnosed when there is: Physical deterioration with a gain in weight: this is the most common way of making the diagnosis and does not require any equipment or particular clinical skill A sudden increase in liver size (this is why the liver is marked before starting any infusion) Tenderness developing over the liver An increase in respiration rate An acute increase in respiration rate of more than five breaths per minute (particularly during rehydration treatment) > 50 breaths/minute in infants > 40 breaths/minute in children aged 1-5 years Respiration that has or develops a grunting sound during each expiration Crepitations in the lungs Prominent superficial and neck veins Engorgement of the neck veins when the abdomen (liver) is pressed Enlargement of the heart (very difficult to assess in practice) Appearance of triple rhythm (very difficult to assess in practice) Increasing oedema or reappearance of oedema during treatment An acute fall in haemoglobin (Hb) concentration (needs laboratory) During the last stage of heart failure development, there is either: 1) marked respiratory distress progressing to a rapid pulse, cold hands and feet, oedema and cyanosis; or 2) sudden, unexpected death. This is known as cardiac shock, it commonly occurs in the severely malnourished child after treatment has started. It has to be differentiated from shock due to dehydration or sepsis because the treatment is quite different. Heart failure is usually preceded by weight gain. As heart failure usually starts after treatment, there is nearly always a record of the weight of the child that was taken before the onset of heart failure. Heart failure and pneumonia are clinically similar and very difficult to tell apart. If there is an increased respiratory rate and any gain in weight, heart failure should be the first diagnosis. If there is an increased respiratory rate with a loss of weight, pneumonia can be diagnosed. If there is no change in weight (fluid balance), the differentiation has to be made using the other signs of heart failure. Pneumonia should not be diagnosed if there has been a gain of weight just before the onset of respiratory distress. Children with oedema can go into heart failure without a gain in weight if the expanded circulation is due to oedema fluid being mobilised from the tissues to the vascular space. During the initial treatment of SAM, any sodium containing fluid that has been given will have to be safely excreted later. Initial over-treatment can lead to death several days later from heart failure when intracellular sodium (marasmus and kwashiorkor) and oedema fluid are being mobilised. As oedema fluid is mobilised (in children with kwashiorkor) and the sodium is coming out of the cells (both kwashiorkor and marasmus), the plasma volume expands and there is a fall in Hb concentration. This dilutional anaemia happens to some extent in nearly all children as they recover. A substantial fall in Hb as a sign of an expanding circulation is also a sign of impending or actual heart failure. These children should never be transfused. Figure 3. Diagnosis of Heart Failure  Treatment of Heart Failure When heart failure is diagnosed: Stop all intakes of oral or IV fluids. No fluid or food should be given until the heart failure has improved. This may take 24-48 hours. Small amounts of sugar water can be given orally to prevent hypoglycaemia. Give frusemide (1 mg/kg bodyweight). Digoxin can be given in single dose (5 micrograms per kilogram bodyweight [g/kg] note that this is lower than the normal dose of digoxin. A loading dose is not given. Use the paediatric preparation and not small quantities of the adult preparation). If heart failure is associated with severe anaemia, the treatment of the heart failure takes precedence over the treatment of the anaemia. A child in heart failure should never be transfused (unless there are facilities and experience with exchange-transfusion). Monitoring Treatment of Heart Failure The following parameters should be monitored: Weight Respiration rate and sound Pulse rate Jugular vein or visible vein engorgement Liver size Heart sounds SEVERE ANAEMIA Diagnosis of Severe Anaemia A child has very severe anaemia if the Hb concentration is less than 40 grams per litre (g/L) or the packed-cell volume is less than 12 percent in the first 24 hours after admission. Management of Severe Anaemia Transfusion is a radical treatment and extremely dangerous for children with SAM who often present with cardiac dysfunctions, reduction in renal function and with iron-carrier protein deficiency. Give 10 ml/kg bodyweight of packed red cells or whole blood slowly over three hours. All children should fast during the procedure and for at least three hours after a blood transfusion. Do not transfuse a child between 48 hours after the start of treatment with F75 until 14 days later. Do not give iron during the stabilisation phase of treatment. If the facilities and expertise exist (neonatal units), it is preferable to give an exchange transfusion to severely malnourished children with severe anaemia. If there is heart failure with very severe anaemia, transfer the child to a health facility with the capacity to perform an exchange transfusion. Heart failure due to anaemia is clinically different from normal heart failure. In heart failure due to anaemia, there is high output failure with an overactive circulation. Increasing anaemia and heart failure or respiratory distress is a sign of fluid overload and an expanding plasma volume. It should be borne in mind that the heart failure is not being caused by the anaemia; these children should never be given a straight transfusion of blood or even packed cells. Figure 4. Diagnosis of Anaemia   EYE SIGNS OF VITAMIN A DEFICIENCY Corneal Ulceration Corneal ulceration is a break in the surface of the cornea (eye's surface). The eye may be extremely red or bleeding, or the child may keep the eye shut. Corneal ulceration is very dangerous. If there is an opening in the cornea, the lens of the eye can extrude (push out) and cause blindness. Give vitamin A immediately (see Table 1 for doses). Oral treatment with vitamin A is preferred, except for initial treatment of children with severe anorexia, oedematous malnutrition or septic shock. IM treatment is preferred for these children for the first dose. For oral administration, an oil-based formulation is preferred. For IM treatment, only water-based formulations should be used. The IM dosage is 100,000 IU (water-based) except for children under age 6 months, who should be given 50,000 IU. Instill one drop atropine (1 percent) into the affected eye(s) to relax the eye and prevent the lens from pushing out. Give chloramphenicol or tetracycline eye drops and bandaging, but this may wait until later in the day. If the child falls asleep with his eyes open, close them gently to protect them. See Table 2for a summary on use of eye drops in case of eye signs. Table 1. Vitamin A Treatment if Eye Signs of Vitamin A Deficiency PRIVATE Child's ageOral Vitamin ADay 1Day 2Day 15< 6 months50,000 IU1 dose1 dose1 dose6-12 months100,000 IU1 dose1 dose1 dose>12 months200,000 IU1 dose1 dose1 dose Eye Infection61 Give chloramphenicol or tetracycline (1 percent) eye drops for treating eye infection or possible eye infection: 1 drop, 4 times daily for 7 days and until eye signs are gone. Give atropine (1 percent) eye drops to relax the eye when there is corneal involvement (i.e., corneal clouding or ulceration): 1 drop, 3 times daily. In some cases, both types of eye drops may be needed. If both types of drops are needed, they may be given at the same time for convenience. For example, give tetracycline 4 times daily and during 3 of those times also give atropine. Use special care and tenderness in examining the eyes and instilling eye drops. To avoid spreading infection, use a separate dropper and bottle for each child. Also be sure to wash hands before and after treating each child. Bandage the affected eyes for 3-5 days until inflammation and irritation subside. Use eye pads soaked in 0.9 percent saline solution, held in place with gauze bandages. The damp pads and bandages will cool the soreness, prevent the child from scratching his/her eyes and promote healing. Change pads and bandages whenever drops are given. To bandage the eyes: Wash hands. Soak eye pads with 0.9 percent saline solution. Place a pad over each affected eye. Wrap a gauze bandage over the pads and around the head (not too tight, just tightly enough to hold in place). Table 2. Summary of Eye Drops Needed for Eye Signs If the child has:Then:Bitots spots only (no other eye signs)No eye drops neededPus or inflammationGive chloramphenicol or tetracycline (1%) eye dropsCorneal clouding or Corneal ulcerationGive both: - chloramphenicol or tetracycline (1%) eye drops - atropine (1%) eye drops SAM AND HIV Dietary management of children with SAM with HIV does not differ from dietary treatment of children with SAM who are HIV-negative. HIV infected children are likely to present more often with associated infection, and therefore rates of weight gain and recovery may be lower than in HIV-negative children. The management of SAM in HIV-infected patients should take into account: High prevalence of Tuberculosis (TB): Always consider diagnosis of TB in HIV-infected patients. The signs are the same as those in children without HIV infection (see SAM and TB, below). Cotrimoxazole prophylaxis: Prophylactic doses of Cotrimoxazole should be given to patients when HIV is suspected, and provision should be indefinite in situations where antiretroviral therapy (ART) is not yet available. This antibiotic is added to the other routine antibiotics for treatment of SAM. ART should be considered for HIV-positive patients with SAM where available: ART is potentially toxic for the child with SAM as it takes several weeks or months before having an impact on the CD4 cell count. Therefore, it is safe to wait until recovery of nutritional status (at least the end of inpatient care) to commence ART treatment. The most appropriate schedule for commencement of ART treatment for children with SAM and HIV infection is, however, not yet established and is currently being investigated Voluntary testing and counselling of children with SAM and their parents in high HIV prevalence areas: Testing for HIV in children with SAM is advised in areas with a high HIV prevalence Infants with SAM of HIV-positive mothers are treated for SAM according to the national guidance on the prevention of mother to child transmission (PMTCT). It has implications for the treatment of SAM and it may lead to detection of HIV in the accompanying parent, with implications for counselling and treatment. If families of HIV-infected children are food insecure, they will also need special nutrition support. Although guidelines for the management of SAM are considered appropriate for HIV-infected patients with the minor adaptations described above, extensive research is currently under way to further adapt protocols for these patients. These include, among other considerations: Comparison of recovery rates of HIV-infected and HIV-negative children with SAM treated in CMAM Development of nutrition products specifically designed for HIV-infected malnourished patients Use of micronutrient supplementation for HIV-infected individuals Development of nutrition support for PLHIV in ART Studies of the interaction between ART and nutritional status of the patient Assessment of SAM in HIV-infected adults Impact of nutrition support on HIV-infected individuals Integration of HIV programmes with CMAM Until such a time where the evidence base is established, it is advised to treat SAM in HIV-infected patients with the standard treatment protocol for SAM, combined with a prophylactic treatment (Cotrimoxazole) and start antiretroviral therapy (ART) after initial recovery of the nutritional status. SAM AND TUBERCULOSIS61 The diagnosis of TB in children relies on careful and thorough assessment of all the evidence derived from a careful history, clinical examination and relevant investigations. Most children with TB have pulmonary TB. The decision to treat a child should be carefully considered, and once such a decision is made, the child should be treated with a full course of therapy. TB in children with SAM is often missed and/or over diagnosed. The presence of three or more of the following key features should strongly suggest a diagnosis of TB in children: Careful history: Contact, and Chronic symptoms suggestive of TB: e.g., prolonged fever (+ 2 weeks), chronic cough (non-remitting for 2-3 weeks), weight loss or failure to thrive (i.e., if SAM no response to treatment) Clinical examination: Physical signs highly suggestive of extrapulmonary TB: e.g., gibbus, especially of recent onset, or non-painful enlarged cervical lymphadenopathy with fistula formation, and Physical signs requiring investigation to exclude extrapulmonary TB: e.g.,, meningitis not responding to antibiotic treatment, distended abdomen with ascitis A positive tuberculin skin test (Mantoux method): i.e., reading after 48 hours with e" 5 mm diameter of induration in high risk children (HIV infected and/or with SAM) and e" 10 mm in all other children Chest X-ray suggestive of TB: e.g., persistent opacification in the lung together with enlarged hilar or subcarinal lymph glands For TB treatment, consult the national treatment protocol for TB in children. OTHER MEDICAL COMPLICATIONS Children diagnosed with SAM may also be suffering from other underlying illnesses. In such circumstances these children should be treated according to this standard protocol for SAM. Those that fail to respond to treatment need further investigation for an underlying condition that makes them fail to respond to treatment. Great care should be exercised in prescribing drugs for children with SAM. They have abnormal kidney and liver function, altered levels of the enzymes necessary to metabolise and excrete drugs, excess entero-hepatic circulation (reabsorption) of drugs that are excreted in the bile, decreased body fat which increases the effective concentration of fat soluble drugs, and in kwashiorkor there may be a defective blood-brain barrier. Moreover, very few drugs have had their pharmacokinetics, metabolism or side effects examined in children with SAM. The following considerations are strongly advised: The underlying malnutrition should be treated first before standard doses of drugs are given. Drugs used for HIV and TB can damage the liver and pancreas. These diseases do not usually cause immediate death (except military TB and TB meningitis) so treatment should normally be delayed for up to one week while the nutritional treatment returns the metabolism of the child back to normal. If it is critical that a particular drug be given at the start of treatment for SAM, then it should initially be administered in reduced doses. Many drugs should be avoided altogether until there is research to show that they are safe and guidance is provided on the dosage appropriate for the malnourished child. Common drugs, such as paracetamol, do not function well in most children with SAM being treated in the stabilisation phase and can cause serious hepatic damage. Metronidazole should be avoided if possible. Ivermectin or other drugs that are dangerous if they cross the blood-brain barrier should never be given to children with bilateral pitting oedema. References Action Contre la Faim (ACF). [no date] Kits for opening new therapeutic care programmes. Ashworth, Ann. 2001. Treatment of severe malnutrition. Journal of Pediatric Gastroenterology and Nutrition 32(5): 516-8. HYPERLINK "http://www.jpgn.org"www.jpgn.org. Ashworth, A, S Khanum, A Jackson, and C Schofield. 2003. Guidelines for the inpatient treatment of severely malnourished children. Geneva: WHO. HYPERLINK "http://www.who.int/nutrition/publications/severemalnutrition/guide_inpatient_text.pdf"http://www.who.int/nutrition/publications/severemalnutrition/guide_inpatient_text.pdf. Black, RE, LH Allen, ZA Bhutta, LE Caulfield, M de Onis, M Ezzati, C Mathers, and J Rivera. 2008. Maternal and child undernutrition: Global and regional exposures and health consequences. The Lancet 371(9608): 243-260. Collins, Steve. 2004. Community-based therapeutic care: A new paradigm for selective feeding in nutritional crisis. HPN Network Paper 48. London, UK: HPN at ODI. HYPERLINK "http://www.odihpn.org/report.asp?id=2685"http://www.odihpn.org/report.asp?id=2685. Concern Worldwide, FANTA, UNICEF and Valid International. 2008. Training guide for community-based management of acute malnutrition (CMAM). Washington, DC: Food and Nutrition Technical Assistance Project (FANTA) at FHI30. HYPERLINK "http://fantaproject.org/cmam/training.shtml"http://fantaproject.org/cmam/training.shtml. De Onis, M, AW Onyango, E Borghi, A Siyam, C Nishida, and J Siekmann. 2007. Development of a WHO growth reference for school-aged children and adolescents. Bulletin of the World Health Organization 85: 660-7. HYPERLINK "http://www.who.int/growthref/growthref_who_bull.pdf"http://www.who.int/growthref/growthref_who_bull.pdf. FANTA. 2003. Anthropometric indicators measurement guide. Washington, DC: FANTA at FHI360. HYPERLINK "http://www.fantaproject.org/publications/anthropom.shtml"http://www.fantaproject.org/publications/anthropom.shtml Ghana Sustainable Change Project. 2008. Priority Nutrition Messages. Accra, Ghana: FHI360. Golden, MH. 1996. Severe malnutrition. Oxford Textbook of Medicine. 3rd edition. pp 1278-96. Oxford, UK: Oxford University Press. Note: later editions of the Oxford Textbook of Medicine do not include this chapter. Golden, MH, and Y Grellety. 2006. Guidelines for the management of the severely malnourished. Draft. Gross, R, and P Webb. 2006. Wasted time for wasted children: Severe child undernutrition must be resolved in non-emergency settings. The Lancet 367: 1209-1211. HYPERLINK "http://www.thelancet.com"www.thelancet.com. IFE Core Group. 2009. Integration of IYCF support into CMAM. Facilitators Guide and Handouts. Oxford, UK: ENN. HYPERLINK "http://fex.ennonline.net/37/integration.aspx"http://fex.ennonline.net/37/integration.aspx ---. 2007. Infant and Young Child Feeding in Emergencies: Operational Guidance for Emergency Relief Staff and Programme Managers. Version 2.1. Oxford, UK: ENN. HYPERLINK "http://www.ennonline.net/pool/files/ife/ops-guidance-2-1-english-010307.pdf"http://www.ennonline.net/pool/files/ife/ops-guidance-2-1-english-010307.pdf. Pelletier, DL, and EA Frongillo. 2003. Changes in child survival are strongly associated with changes in malnutrition in developing countries. Journal of Nutrition 133: 107-19. HYPERLINK "http://jn.nutrition.org/cgi/content/abstract/133/1/107"http://jn.nutrition.org/cgi/content/abstract/133/1/107 Teaching-Aids at Low Cost (TALC). 2000. Topics in international health. London, UK: The Wellcome Trust. HYPERLINK "http://www.talcuk.org/cd-roms/topics-in-international-health-nutrition.htm"www.talcuk.org/cd-roms/topics-in-international-health-nutrition.htm. The Sphere Project. 2010. Humanitarian Charter and Minimum Standards in Disaster Response. Draft. Geneva: The Sphere Project. ---. 2004. Humanitarian Charter and Minimum Standards in Disaster Response. Oxford, UK: Oxfam. HYPERLINK "http://www.sphereproject.org/component/option,com_docman/task,cat_view/gid,70/Itemid,203"http://www.sphereproject.org/component/option,com_docman/task,cat_view/gid,70/Itemid,203 Valid International. 2006. Community-based therapeutic care: A Field Manual. First edition. Oxford, UK: Valid International. HYPERLINK "http://www.fantaproject.org/ctc/manual2006.shtml"http://www.fantaproject.org/ctc/manual2006.shtml. WHO. (Pending). Guideline on community-based management of severe acute malnutrition. (Draft) ---. 2009. Rapid advice: Revised WHO principles and recommendations on infant feeding in the context of HIV. Geneva: WHO. HYPERLINK "http://www.who.int/child_adolescent_health/documents/9789241598873/en/index.html"http://www.who.int/child_adolescent_health/documents/9789241598873/en/index.html. ---. 2007. WHO reference 2007, Growth reference data for 5-19 years. Geneva: WHO. HYPERLINK "http://www.who.int/growthref/en/"http://www.who.int/growthref/en/. ---. 2006, Guidance for national tuberculosis programmes on the management of tuberculosis in children. Geneva: WHO. HYPERLINK "http://whqlibdoc.who.int/hq/2006/WHO_HTM_TB_2006.371_eng.pdf"http://whqlibdoc.who.int/hq/2006/WHO_HTM_TB_2006.371_eng.pdf ---. 2006. Management of the child with a serious infection or severe malnutrition: Guidelines for care at the first-referral level in developing countries. Geneva: WHO. HYPERLINK "http://www.who.int/child_adolescent_health/documents/fch_cah_00_1/en/"http://www.who.int/child_adolescent_health/documents/fch_cah_00_1/en/ ---. 2006. Home-Modified Animal Milk for Replacement Feeding: Is It Feasible and safe? Consultation background document. Geneva: WHO. HYPERLINK "http://whqlibdoc.who.int/HQ/2006/a91064.pdf"http://whqlibdoc.who.int/HQ/2006/a91064.pdf. ---. 2004. Guiding principles for feeding infants and young children in emergencies. Geneva: WHO. HYPERLINK "http://whqlibdoc.who.int/hq/2004/9241546069.pdf"http://whqlibdoc.who.int/hq/2004/9241546069.pdf. ---. 2002. Training course on the management of severe malnutrition. Geneva: WHO. HYPERLINK "http://www.who.int/nutrition/publications/malnutrition/en/index.html"http://www.who.int/nutrition/publications/malnutrition/en/index.html ---. 2000. Management of the child with a serious infection or severe malnutrition: Guidelines for care at the first-referral level in developing countries. Geneva: WHO. HYPERLINK "http://whqlibdoc.who.int/hq/2000/WHO_FCH_CAH_00.1.pdf"http://whqlibdoc.who.int/hq/2000/WHO_FCH_CAH_00.1.pdf. ---. 1999. Management of severe malnutrition: A manual for physicians and other senior health workers. Geneva: WHO. HYPERLINK "http://www.who.int/nutrition/publications/severemalnutrition/9241545119/en/"http://www.who.int/nutrition/publications/severemalnutrition/9241545119/en/. WHO and UNICEF. 2009. WHO child growth standards and the identification of severe acute malnutrition in infants and children: A Joint Statement by the World Health Organization and the United Nations Childrens Fund. Geneva: WHO. HYPERLINK "http://www.who.int/nutrition/publications/severemalnutrition/9789241598163/en/index.html"http://www.who.int/nutrition/publications/severemalnutrition/9789241598163/en/index.html ---. 2003. Global Strategy for Infant and Young Child Feeding. Geneva: WHO. HYPERLINK "http://www.who.int/nutrition/publications/infantfeeding/9241562218/en/index.html"http://www.who.int/nutrition/publications/infantfeeding/9241562218/en/index.html. WHO, WFP, UN/SCN and UNICEF. 2007. Community-based management of severe acute malnutrition: A Joint Statement by the World Health Organization, the World Food Programme, the United Nations System Standing Committee on Nutrition and the United Nations Childrens Fund. Geneva: WHO. HYPERLINK "http://www.who.int/nutrition/publications/severemalnutrition/978-92-806-4147-9/en/index.html"http://www.who.int/nutrition/publications/severemalnutrition/978-92-806-4147-9/en/index.html ---. 2006. Informal consultation on the community-based management of severe malnutrition in children. Food and Nutrition Bulletin 27(3): Supplement. Geneva: WHO. HYPERLINK "http://www.fantaproject.org/publications/fnb27.shtml"http://www.fantaproject.org/publications/fnb27.shtml.  A good nutrition indicator detects as many people at risk as possible (sensitivity) without including too many people who are not at risk (specificity). A good nutrition indicator should also be functionally meaningful (i.e., related to the risk of morbidity and mortality) and be sensitive to change.  When body measurements are compared to a reference value, they are called nutrition indices.  WHO. 2000. The management of nutrition in major emergencies. Geneva: WHO.  WHO, WFP, UN/SCN and UNICEF. 2007. Community-Based Management of Severe Acute Malnutrition: A Joint Statement by the World Health Organization, the World Food Programme, the United Nations System Standing Committee on Nutrition and the United Nations Childrens Fund. Geneva: WHO; WHO and UNICEF. 2009. WHO child growth standards and the identification of severe acute malnutrition in infants and children: A Joint Statement by the World Health Organization and the United Nations Childrens Fund. Geneva: WHO.  Black, RE, LH Allen, ZA Bhutta, LE Caulfield, M de Onis, M Ezzati, C Mathers, and J Rivera. 2008. Maternal and child undernutrition: Global and regional exposures and health consequences. The Lancet 371(9608): 243-60.  Gross, R, and P Webb. 2006. Wasted time for wasted children: Severe child undernutrition must be resolved in non-emergency settings. The Lancet 367: 1209-11.  Infection leads to loss of appetite in the acute phase. In addition, liver and metabolic disturbances that accompany Type 2 nutrient deficiency also leads to loss of appetite in children with SAM.  WHO. 1999. Management of severe malnutrition: A manual for physicians and other senior health workers. Geneva: WHO; WHO, WFP, UN/SCN and UNICEF. 2007. Community-Based Management of Severe Acute Malnutrition: A Joint Statement by the World Health Organization, the World Food Programme, the United Nations System Standing Committee on Nutrition and the United Nations Childrens Fund. Geneva: WHO; WHO and UNICEF. 2009. WHO child growth standards and the identification of severe acute malnutrition in infants and children: A Joint Statement by the World Health Organization and the United Nations Childrens Fund. Geneva: WHO.  IFE Core Group. 2009. Integration of IYCF support into CMAM. Facilitators Guide and Handouts. Oxford, UK: ENN.  WHO. 1999. Management of severe malnutrition: a manual for physicians and other senior health workers. Geneva: WHO; WHO, WFP, UN/SCN and UNICEF. 2007. Community-Based Management of Severe Acute Malnutrition: A Joint Statement by the World Health Organization, the World Food Programme, the United Nations System Standing Committee on Nutrition and the United Nations Childrens Fund. Geneva: WHO; WHO and UNICEF. 2009. WHO child growth standards and the identification of severe acute malnutrition in infants and children: A Joint Statement by the World Health Organization and the United Nations Childrens Fund. Geneva: WHO.  Ashworth, A, S Khanum, A Jackson, and C Schofield. 2003. Guidelines for the inpatient treatment of severely malnourished children. Geneva: WHO.  This is an acceptable approximation. If tables are to be constructed, 100 ml of F100 = 18.5 g of RUTF: 10 g of RUTF = 54 ml of F100 should be used and the resulting values rounded to the nearest 5 or 10 ml.  This is an acceptable approximation. If tables are to be constructed, 100 ml of F100 = 18.5 g of RUTF: 10 g of RUTF = 54 ml of F100 should be used and the resulting values rounded to the nearest 5 or 10 ml.  Idem.  Gastric aspirates are very rarely positive in the malnourished child with active TB, particularly if there is overnight feeding; this test should not be relied on, is difficult to perform well and is traumatic for the child. If it is used, overnight feeds should not be given. 28 IFE Core Group. 2009. Integration of IYCF into CMAM. Facilitators Guide and Handouts. Oxford, UK: ENN.  WHO and UNICEF. 2003. Global Strategy for Infant and Young Child Feeding. Geneva: WHO; IFE Core Group. 2007. Infant and Young Child Feeding in Emergencies: Operational Guidance for Emergency Relief Staff and Programme Managers. Version 2.1. Oxford, UK: ENN.  WHO. 2009. Rapid advice: Revised WHO principles and recommendations on infant feeding in the context of HIV. Geneva: WHO.  Note: F100-Diluted has a lower osmolarity than some readily-available infant formulae and thus has a lower risk of causing diarrhea. Studies have shown that F100-Diluted and some infant formulae give similar results in terms of mortality and weight gain. 32 IFE Core Group. 2009. Integration of IYCF Support into CMAM. Facilitators Guide and Handouts. Oxford, UK: ENN.  WHO. 1999. Management of severe malnutrition: A manual for physicians and other senior health workers. Geneva: WHO.  There is neither evidence nor international agreement on the cutoff.  A reasonable randomised sample of treatment cards of discharged cured cases is 20. If lower numbers have been discharged cured during the period of reporting, take all treatment cards.  Idem.  The Sphere Project. 2010. Humanitarian Charter and Minimum Standards in Disaster Response. Draft. Geneva: The Sphere Project. (The Sphere Standards)  WHO. 1999. Management of severe malnutrition: A manual for physicians and other senior health workers. Geneva: WHO.  FANTA. 2003. Anthropometric Indicators Measurement Guide. Washington, DC: FANTA at FHI 360.  WHO. 2007. WHO Reference 2007, Growth reference data for 5-19 years. Geneva: WHO.  De Onis, M, AW, Onyango, E Borghi, A Siyam, C Nishida, and J Siekmann. 2007. Development of a WHO growth reference for school-aged children and adolescents. Bulletin of the World Health Organization 85: 660-7.  WHO. 2002. Training course on the management of severe malnutrition. Geneva: WHO.  WHO. 2006. Home-Modified Animal Milk for Replacement Feeding: Is It Feasible and Safe? Consultation background document. Geneva: WHO. 46 WHO, WFP, UN/SCN and UNICEF. 2007. Community-Based Management of Severe Acute Malnutrition: A Joint Statement by the World Health Organization, the World Food Programme, the United Nations System Standing Committee on Nutrition and the United Nations Childrens Fund. Geneva: WHO.  Adapted from: Ghana Sustainable Change Project. 2008. Priority Nutrition Messages. Accra, Ghana: FHI 360.  IFE Core Group. 2009. Integration of IYCF support into CMAM. Facilitators Guide and Handouts. Oxford, UK: ENN.  Ghana Sustainable Change Project. 2008. Priority Nutrition Messages. Accra, Ghana: FHI 360.  WHO 1999. Management of severe malnutrition: A manual for physicians and other senior health workers. Geneva: WHO.  Gastric aspirates are very rarely positive in the malnourished child with active TB, particularly if there is overnight feeding. This test should not be relied on, is difficult to perform well and is traumatic for the child. If it is used, overnight feeds should not be given.  Adapted from: Critical Care Pathway-CCP in: WHO. 2002. Training course on the management of severe malnutrition. Geneva: WHO.  Adapted from: WHO. 2002. Training Course on the Management of Severe Malnutrition. Geneva: WHO.  Adapted from: Action Contre la Faim (ACF). [no date] Kits for opening new therapeutic care programmes.  Adapted from: Valid International. 2006. Community-based Therapeutic Care (CTC): A Field Manual. Oxford, UK: Valid International.  If outpatient care is functioning well, the inpatient caseload should be low (normally five-to-10 patients per district in inpatient care, depending on the catchment area and prevalence of SAM).  Adapted from: Golden, MH, and Y Grellety. 2006. Guidelines for the management of the severely malnourished. Draft.  The orbit contains an eye, small muscles and nerves, fat, the lachrymal gland and a venous plexus. In marasmus, the fat and the lachrymal gland atrophy so that the eyes sink. In dehydration, there is contraction of the venous plexus forcing blood out of the orbit so that the eyes sink.  Toxic shock may be caused by traditional medicines or self treatment with other medicine such as aspirin, paracetamol, metronidazole, etc. Septic shock is a specific type of toxic shock where the damage is caused by overwhelming sepsis. These are frequently associated with liver failure.  Hanging pants used for surveys should not be used to weigh sick children in health facilities or those likely to soil the pants and pass infection to the next child.  This is the same as hyper-osmolar syndrome and other synonyms that denote that the plasma osmolarity is increased above normal. The increased osmoles can be urea if a very high protein diet has been taken or there is inadequate renal function or it can be glucose in patients with glucose intolerance.  The dry atmosphere is the more important feature. Where the climate is very hot and wet, much less water is lost so that the child presents first with fever because of an inability to excrete the heat generated during metabolism.  All infant formulae have a very much-higher renal solute load than breast milk. In very hot and dry climates even correctly made up infant formulae can result in hypernatraemic dehydration. This is a real danger that arises from the failure of breastfeeding in such climates. Because of the low renal solute load of human breast milk, exclusive breastfeeding is the best way to avoid hypernatraemic dehydration.  If the child is small, this can be in an incubator similar to that used for neonates. It can also be achieved with aerosol sprays into the atmosphere or a humidifying tent, such as that used to treat bronchiolitis. If such facilities are not available, hanging wet sheets in the room or spraying the walls with water intermittently will both humidify and cool the atmosphere. Wet clothes should not be placed directly onto the child unless he/she has a high fever. In one study in Chad (daytime climate of 43 C with 15 percent humidity), the turnover of water in malnourished children was one-third of body water per day (250 ml/kg bodyweight/day). It is critical to prevent this ongoing excessive water loss, otherwise it is very difficult to judge the amount of fluid to give the child that is needed for slow rehydration, which is a relatively small faction of the requirements for replacing ongoing losses, which are unmeasured and very difficult to assess with any accuracy. The only way to judge on-going losses and the rate of rehydration is with serial accurate weights.  The extracellular fluid volume is about 250 ml/kg bodyweight, depending on the level of body fat and the extent of cellular atrophy. If the extracellular sodium concentration is about 160 mmol/L and this is to be reduced by 12 mmol/day, the extracellular fluid should be expanded by about 0.75 percent per day. However, the extra water given will be distributed in both the intra- and extracellular compartments, so it is necessary to have a positive water balance of 0.75 percent of body water per day. There is a higher body water percentage in malnourished children than in normal children. Therefore, the daily positive water balance should be about 60 ml/kg bodyweight/day, which equals 2.5 ml/kg bodyweight/hour.  Sugar-water should be used rather than plain water. It is isotonic and so empties from the stomach, and is absorbed more quickly. The treatment will last for about 48 hours. Sugar water prevents hypoglycaemia in these children.  All children have a fall in Hb during the early phase of treatment. This dilutional anaemia is due to the sodium coming of the cells and mobilization of oedema it must not be treated.  WHO. 2002. Training course on the management of severe malnutrition. Geneva: WHO.  WHO. 2006. Guidance for national tuberculosis programmes on the management of tuberculosis in children. Geneva: WHO.      Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010  PAGE 75  PAGE 83 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010  Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010  PAGE \* MERGEFORMAT 112 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010  PAGE \* MERGEFORMAT 114  Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010  PAGE \* MERGEFORMAT 160 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010  PAGE 115  PAGE \* MERGEFORMAT 162  PAGE \* MERGEFORMAT 164    PAGE \* MERGEFORMAT 176     PAGE \* MERGEFORMAT 167  Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010  PAGE \* MERGEFORMAT 174  Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010  PAGE \* MERGEFORMAT 177  Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 PAGE   PAGE \* MERGEFORMAT 229 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010  PAGE \* MERGEFORMAT 203 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 Generic Guidelines and Job Aids for Community-Based Management of Acute Malnutrition (CMAM), November, 2010 CONSIDER: Your country may use another term than CMAM for the management of SAM and MAM. CONSIDER: Guidelines may be expanded to include the management of moderate acute malnutrition adhering to the WHOs 2006 Child Growth Standards, and reflecting new evidence and best practices in the management of MAM. Check back to the FANTA website for new versions that incorporate latest protocols and recommendations. CONSIDER: Your country may use millimetres or centrimetres to measure MUAC. CONSIDER: This section will be written based on your countrys current nutrition situation. Box 1. 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7$8$H$gdtgdtgdjgdgd.`gdoLeeeeTeUe_eeeeeeee;<@Aؠ٠ɤʤ跨葃ywjyjyjWjyjHhth1+0J^JmH sH %jhth1+0JU^JmH sH hth1+^JmH sH Uh1+^JmH sH hth1+5^JmH sH h1+5^JmH sH h1+B* ^JaJphc$#hth1+B* ^JaJphc$#!hth1+B* CJ^JaJphc$#hXLlh1+B* ^JaJphc$#!hXLlh1+B* CJ^JaJphc$#h1+%hh1+B* CJOJQJaJphc$#Malnutrition rates have soared in [COUNTRY] because of poor health conditions, suboptimal maternal and child feeding and care practices, and food insecurity. This has been compounded by high rates of poverty and illiteracy, long years of civil strife and recurrent environmental shocks (e.g., floods, droughts). The [__] percent prevalence of wasting is significantly higher than the WHO 15 percent threshold for nutrition emergencies. Among children under 5, stunting affects [__] percent and underweight affects [__] percent. Few data exist on the prevalence of vitamin and mineral deficiencies, but they are expected to be widespread given the general malnutrition situation; for instance, only [__]percent of children under 5 currently receive vitamin A supplementation. Among young children, [COUNTRY] has a heavy burden of communicable diseases most associated with undernutrition, such as fever, acute respiratory infection and diarrhoea. At the same time, appropriate health-seeking behaviour is limited and the health system struggles to meet the needs of the country for primary care. At any given time, [__] percent of children have a fever, but only [__] percent receive treatment. A __] percent of children are fully immunised. The health infrastructure is [__]. IYCF practices are [__]inadequate. Inappropriate breastfeeding practices and low dietary quality of complementary foods are recognised as the major causes of undernutrition in infants and young children. Throughout [COUNTRY], [__] percent of infants are exclusively breastfed and [__] percent of children 6-11 months receive complementary foods. Dietary diversity [___] [and food prescriptions/taboos] prevent mothers and young children from consuming many of the accessible nutritious foods]. Environmental health and hygiene are [__], with [__] percent of households having access to improved drinking water sources and [__]percent of households safely disposing of excreta. Access to and availability [__]. [__] percent of the population lives on less than 1 United States (US) dollar per day and [__] percent of households experience poor food consumption. With [__] percent of the population unable to read and the economy [__], food security is [__]precarious. Outpatient care for mgmt of SAM without medical complications Prevention of Undernutrition Inpatient care for mgmt of SAM with medical complications Community Outreach for community involvement and active case finding Mgmt of MAM CONSIDER: This section should describe current CMAM services and programs in your country. CONSIDER: This section should describe the current policy framework. CONSIDER: This section should describe the national strategy and implementation for CMAM. CONSIDER: This section should describe a Community Outreach strategy for CMAM that is most appropriate to the context of your country. The section provides guidance for community-outreach at the district level. Where there may not be good knowledge of community outreach systems, one could consider doing a national-level community outreach assessment to better understand the existing services and opportunities, and further strengthen and build upon the existing health outreach systems. CONSIDER: Standardised messages will be developed and adapted to the local context of [COUNTRY] and are expected to be used in materials including pamphlets or radio messages. Box 3. Community Screening and Referral for Treatment Presence of bilateral pitting oedema MUAC < 115 mm (children 6 -59 months) Note: Infants under 6 months with bilateral pitting oedema or visible wasting or at high risk of death because of inadequate feeding are referred to the health facility for investigation, or linked with adequate infant feeding support services. Planning Phase Building upon strengthening existing community initiatives 1. Community Assessment 4. Training for Community Outreach 8. Linking with Other Community Initiatives 7. Home Visits 6. Case Finding and Referral 5. Community Mobilization Implementation Phase 3. Messages and Materials 2. Outreach Strategy Box 4. Admission and Initial Treatment Procedures Waiting area, welcome the child and caregiver: Welcome the child and the caregiver, provide shelter and drinking water Prioritize critically ill children to have first access. Provide sugar water to all children to avoid hypoglycaemia. Sugar-water solution should contain approximately 10 percent sugar solution (10 grams (g) of sugar per 100 millilitres (ml) of water). Define nutritional status: Check for bilateral pitting oedema, take MUAC, and if equipment, time and skills measure weight and height. Use the admission criteria (see Table 3) to guide decision making for admission. Indicate target weight for discharge at 15 percent weight gain (of admission weight or weight free of oedema) (see Annex 5. Guidance Table to Identify Target Weight for Discharge). Register the child and record measurements on treatment card. Conduct a medical assessment: Take the childs medical history, conduct a physical examination, determine if the child has a minor health problem or a medical complication, and record on the treatment card. Fast-track children with SAM with medical complications in need of inpatient care for referral and start treatment (no need for appetite test, administer first dose antibiotic). Test the appetite (see Box 5). The appetite test is a critical criterion for deciding whether a child with SAM without medical complications is treated in outpatient care or in inpatient care. Decide whether to treat the child with SAM in outpatient care or refer to inpatient care (triage) Provide treatment: Provide treatment for underlying infections and decide if treatment for additional health conditions is needed. Provide weekly (or biweekly) amount of RUTF based on +- daily 200 kcal of RUTF per kg bodyweight (see Annex 11. Dietary Treatment). Counsel the caregiver on key messages for treatment, the intake of antibiotics and RUTF, and care practices, and instruct him/her to return to the health facility for monitoring sessions or whenever a problem arises (see Annex 18. Key Messages Upon Admission to Outpatient Care). Link the caregiver with the community outreach worker. Link the caregiver with other health and community services or initiatives as appropriate. ADMISSION Screening: Measure anthropometry and check bilateral pitting oedema If SAM without medical complication and passed appetite test If SAM with medical complication and/or failed appetite test Admission to Inpatient Care Referral for treatment in inpatient care: medical complication developed, decreased appetite, weight loss or stagnant weight, oedema increase or no decrease (See Action Protocol) Admission to Outpatient Care Medical History and Physical Examination: - Evaluate nutritional status and health condition - Check for medical complications - Perform the appetite test TREATMENT SAM treatment completed (based on discharge criteria): Discharge from treatment and refer to supplementary feeding and/or other health and community services that address underlying causes of malnutrition Treatment Treatment Referral for continuing treatment in outpatient care: Appetite returning (passed appetite test) Oedema decreasing Medical complication resolving No iron With iron Box 10. Frequent Causes of Failure to Respond to Treatment in Inpatient Care Problems Related to the Health Facility Poor environment for malnourished children Lack of adherence to treatment protocols for SAM Failure to treat malnourished children in a separate area Failure to complete the individual treatment card (multi-chart) correctly, resulting in gaps in data for monitoring the childs progress Insufficient staff (particularly at night) or inadequately trained staff Inadequate supervision and constant rotation of staff in treatment facility Inaccurate weighing machines Food prepared or given incorrectly Problems Related to the Individual Child Insufficient feeds given Vitamin and mineral deficiencies Malabsorption of food Psychological trauma (particularly in refugee situations and families living with HIV) Rumination Infection, especially: diarrhoea (amaebiasis, giardiasis, dysentery), pneumonia, TB, urinary infection/otitis media, malaria, HIV, schistosomiasis, kalazar/leishmaniasis, hepatitis/cirrhosis Other serious underlying disease: congenital abnormalities (e.g., Downs syndrome), neurological damage (e.g., cerebral palsy), inborn errors of metabolism CONSIDER: Your country decides the appropriate period of time to determine relapse or new episode of illness (e.g., before/after three months). Stable Loss STOP ALL rehydration fluid Give F75 Re-diagnose & assess Increase ReSoMal by 5 ml/kg/hour Reassess every hour Increase ReSoMal by 10 ml/kg/hour Reassess every hour Continue Target Weight F75 Gain Clinically improved Clinically not improved Monitor Weight ONLY rehydrate until the weight deficit (measured or estimated) is corrected ReSoMal - 5 ml/kg/30 min first 2 hrs - 5 to 10 ml/kg/hr 12 hours IV fluid Darrows solution or 1/2 saline & 5% glucose or Ringer lactate & 5% dextrose at 15 ml/kg the first hour & reassess - If improving, 15 ml/kg 2nd hour; - If conscious, NGT: ReSoMal - If not improving => Septic shock Dehydrated Child Conscious Unconscious Respiratory distress Heart failure Fluid overload Pneumonia (Aspiration) Examine daily weights Weight increase Weight decrease Weight stable ANAEMIA Check Hb at admission if any clinical signs of anaemia -Hb<=40g/l or -Packed cell volume >=12% Or between day 2 and 14 after admission ONLY the first 48 hours after admission: Give 10ml/kg whole or packed cells over 3 hours No food for 6 hours No acute treatment Iron is given during rehabilitation phase of treatment -Hb<40g/l or -Packed cell volume <12% Introduction Introduction Community Outreach 2. Community Outreach 3. Outpatient Care 3. Outpatient Care 4. Inpatient Care 4. Inpatient Care 5. Infants Under 6 Months 5. Infants Under 6 Months 6. Older Age Groups 6. Older Age Groups 7. Monitoring and Reporting 7. 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/ / / / / / / / / p<Tkd$$IfTlֈ*. 26U"K <044 lap<T$$If!vh#v#v#v#vK:V l <0,5555K/ / / / / / / / / / p<Tkd$$IfTlֈ*. 26U"K <044 lap<T$$If!vh#v#v#v#vK:V l <0,5555K/ / / / / / / / / / p<Tkd$$IfTlֈ*. 26U"K <044 lap<T$$If!vh#v#v#v#vK:V l <0,5555K/ / / / / / / / / / p<TkdY$$IfTlֈ*. 26U"K <044 lap<T$$If!vh#v#v#v#vK:V l <0,5555K/ / / / / / / / / / p<Tkd'$$IfTlֈ*. 26U"K <044 lap<T$$If!vh#v#v#v#vK:V l <0,5555K/ / / / / / / / / / p<Tkd $$IfTlֈ*. 26U"K <044 lap<T$$If!vh#v#v#v#vK:V l <0,5555K/ / / / / / / / / / p<Tkd$$IfTlֈ*. 26U"K <044 lap<T$$If!vh#v#v#v#vK:V l <0,5555K/ / / / / / / / / / p<Tkd$$IfTlֈ*. 26U"K <044 lap<T$$If!vh#v#v#v#vK:V l <0,5555K/ / / / / / / / / / p<Tkd_$$IfTlֈ*. 26U"K <044 lap<T$$If!vh#v#v#v#vK:V l <0,5555K/ / / / / / / / / / p<Tkd-$$IfTlֈ*. 26U"K <044 lap<T$$If!vh#v#v#v#vK:V l <0,5555K/ / / / / / / / / / p<Tkd$$IfTlֈ*. 26U"K <044 lap<T$$If!vh#v#v#v#vK:V l <0,5555K/ / / / / / / / / / p<Tkd!$$IfTlֈ*. 26U"K <044 lap<T$$If!vh#v#v#v#vK:V l <0,5555K/ / / / / / / / / / p<Tkd%$$IfTlֈ*. 26U"K <044 lap<T$$If!vh#v#v#v#vK:V l <0,5555K/ / / / / / / / / / p<Tkde)$$IfTlֈ*. 26U"K <044 lap<T$$If!vh#v#v#v#vK:V l <0,5555K/ / / / / / / / / / p<Tkd3-$$IfTlֈ*. 26U"K <044 lap<T$$If!vh#v#v#v#vK:V l <0,5555K/ / / / / / / / / / p<Tkd1$$IfTlֈ*. 26U"K <044 lap<T$$If!vh#v#v#v#vK:V l <0,5555K/ / / / / / / / / / p<Tkd4$$IfTlֈ*. 26U"K <044 lap<T$$If!vh#v#v#v#vK:V l <0,5555K/ / / / / / / / / / p<Tkd8$$IfTlֈ*. 26U"K <044 lap<T$$If!vh#v#v#v#vK:V l <0,5555K/ /  / / / /  / / p<Tkdk<$$IfTlֈ*. 26U"K <044 lap<T$$If!vh#v #:V l0,5 #/ Tb$$If!vh#vA#v #v#v:V l4 (0+++,5A5 55/ /  / / /  / f4p(Tb$$If!vh#vA#v#v#v:V l4 (0+++,5A555/ /  / / /  / f4p(TkdB$$IfTl4ֈ c# A   (044 laf4p(T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / p<TkdTE$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<TkdI$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<TkdL$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<TkdP$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<TkdpT$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd>X$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd \$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd_$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkdc$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkdvg$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<TkdDk$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkdo$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkdr$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkdv$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd|z$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<TkdJ~$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<TkdP$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<TkdV$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd\$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd*$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkdb$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd0$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkdh$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd6$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ / / / / / / / / / p<Tkd$$IfTlֈ c#A <044 lap<T$$If!vh#vA#v#v#v:V l <0,5A555/ /  / / / /  / / p<Tkdn$$IfTlֈ c#A <044 lap<T$$If!vh#v}#:V l40,5}#/ f4T$$If!vh#v#v\ #v :V l4 0+,55\ 5 / / /  f4pTw$$If!vh#v#vT#v#v#v:V l4 20+,55T555/ / /  /  / f4p2Tu$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2T$$If!vh#v#vT#v#v:V l 20,55T55/ / / / / / / / p2Tg$$If!vh#v#vT#v#v:V l 20,55T55/  / / /  / / p2T$$If!vh#v:V - ,5/ / / 44 ` pT$$If!vh#v:V  ,59/ / / / 44 ` pT$$If!vh#v:V  ,59/ / / 44 ` pT$$If!vh#v:V  ,59/ / / 44 ` pT$$If!vh#v:V  ,59/ / / 44 ` pT$$If!vh#v:V  ,59/ / / 44 ` pT$$If!vh#v:V  ,59/  / 44 ` pT$$If!vh#v:V  ,59/  / 44 ` pT$$If!vh#v:V  ,59/  / / 44 ` pT$$If!vh#v:V u ,5/ / / 44 ` apT$$If!vh#v:V 3 ,59/ / / / 44 ` apT$$If!vh#v:V G ,59/ / / 44 ` apT$$If!vh#v:V  ,59/ / / 44 ` apT$$If!vh#v:V = ,59/ / / 44 ` apT$$If!vh#v:V _ ,59/ / / 44 ` apT$$If!vh#v:V  ,59/  / 44 ` apT$$If!vh#v:V  ,59/  / 44 ` apT$$If!vh#v:V  ,59/  / / 44 ` apTN$$Ifl!vh#v#v#v :V 4 0555 / / / / /  / / 44 alf4pJ$$Ifl!vh#v#v#v :V 4 0555 / / / / / / / 44 alf4pJ$$Ifl!vh#v#v#v :V 4 0555 / / / / / / / 44 alf4pJ$$Ifl!vh#v#v#v :V 4 0555 / /  / / / /  / 44 alf4p$$If!vh#v#v:V s4 0+,5544 spT$$If!vh#v#v #v :V s4 0+55 5 44 spT$$If!vh#v#v #v :V s 055 5 44 spT$$If!vh#v#v #v :V s 055 5 44 spT$$If!vh#v#v#v#v7#v#v#v:V F 6,55557555/ / / /  / / 22 l4 alpFkdK$$If֞ U 7 F 622 l4alpF$$If!vh#v#v#v#v7#v#v#v:V 4 F 6+,55557555/ / / / / /  / / 22 l4 alpFkdO$$If4֞ U 7 F 622 l4alpF$$If!vh#v#v#v#v7#v#v#v:V 4 < 6+55557555/ / / / / /  / / 22 l4 alp<kdQS$$If4֞ U 7  < 622 l4alp<$$If!vh#v#v#v#v7#v#v#v:V 4 < 6+55557555/ / / / / /  / / 22 l4 alp<kdV$$If4֞ U 7  < 622 l4alp<$$If!vh#v#v#v#v7#v#v#v:V 4 < 6+55557555/ / / / / /  / / 22 l4 alp<kd{Z$$If4֞ U 7  < 622 l4alp<y$$If!vh#vJ#vK#v@#v#vQ#v:V <6,5J5K5@55Q5/ / / /  / / 22 l4 alp<$$If!vh#vJ#vK#v@#v#vQ#v:V 4 <6+,5J5K5@55Q5/ / / / / / /  / / 22 l4 alp<$$If!vh#vJ#vK#v@#v#vQ#v:V 4 26+,5J5K5@55Q5/ / / / / / /  / / 22 l4 alp2$$If!vh#vJ#vK#v@#v#vQ#v:V 4 26+,5J5K5@55Q5/ / / / / / /  / / 22 l4 alp2$$If!vh#vJ#vK#v@#v#vQ#v:V 4 26+,5J5K5@55Q5/ / / / / / /  / / 22 l4 alp2$$Ifl!vh#v :V l   t06,5 alpT$$Ifl!vh#v :V l  t06,5 alpT$$Ifl!vh#v :V l  t06,5 alpT$$Ifl!vh#v :V l  t06,5 / alpT$$Ifl!vh#v :V l  t06,5 / / alpT$$Ifl!vh#v :V l   t06,5 alpT$$Ifl!vh#v :V l  t06,5 alpT$$Ifl!vh#v :V l  t06,5 alpT$$Ifl!vh#v :V l  t06,5 / alpT$$Ifl!vh#v :V l  t06,5 / / alpT$$Ifl!vh#v :V l   t06,5 alpT$$Ifl!vh#v :V l  t06,5 alpT$$Ifl!vh#v :V l  t06,5 alpT$$Ifl!vh#v :V l  t06,5 / alpT$$Ifl!vh#v :V l  t06,5 / / alpT$$If!vh#v :V l   t06,,5 / pT$$If!vh#v :V l  t06,5 / pT$$If!vh#v :V l  t06,5 / pT$$If!vh#v :V l  t06,5 / pT$$If!vh#v :V l  t06,5 / / / pT$$If!vh#v :V l  t06,5 / pT$$If!vh#v :V l  t06,5 / pT$$If!vh#v :V l  t06,5 / pT$$If!vh#v :V l  t06,5 / pT$$If!vh#v :V l  t06,5 / / pT^$$If!vh#vg:V l   t(0!6,,,,5g/ / / / / / / / p(TH$$If!vh#vg:V l  t(0!6,5g/ / / / / / / / p(Td$$If!vh#vg:V l  t(0!6,5g/ / / / / / / / / / p(Td$$If!vh#vg:V l  t(0!6,5g/ / / / / / / / / / p(Td$$If!vh#vg:V l  t(0!6,5g/ / / / / / / / / / p(Td$$If!vh#vg:V l  t(0!6,5g/ / / / / / / / / / p(TL$$If!vh#vg:V lK  t(0!6,5g/ / / / / / / / p(T9$$Ifl!vh#v:V l  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_Toc206819254 _Toc252195273 _Toc259700193 _Toc206819256 _Toc206819258 _Toc234659743 _Toc206819289 _Toc232411937 _Toc232486690 _Toc259691641 _Toc259691642 _Toc234659744 _Toc259691643 _Toc259656949 _Toc259691644 _Toc259691645 _Toc259691646 _Toc259691647 _Toc234659745 _Toc259691648 _Toc252195274 _Toc259700194 _Toc234659746 _Toc259691649 _Toc259691650 _Toc234659747 _Toc259691651 _Toc234659749 _Toc259691652 _Toc232411938 _Toc232486691 _Toc234659750 _Toc259691653 _Toc232411939 _Toc206819291 _Toc259691654 _Toc232411941 _Toc259691655 _Toc206819292 _Toc259691656 _Toc206819300 _Toc259700195 _Toc232411942 _Toc232486692 _Toc234659751 _Toc234659752 _Toc259691657 _Toc206819293 _Toc234659753 _Toc259691658 _Toc259691659 _Toc234659754 _Toc259691660 _Toc259691661 _Toc206819311 _Toc206819303 _Toc234659767 _Toc259691662 _Toc259691663 _Toc259691664 _Toc259691665 _Toc252195276 _Toc259700196 _Toc259691666 _Toc232411961 _Toc232486696 _Toc232837416 _Toc232850543 _Toc259691667 _Toc198363775 _Toc199218131 _Toc199932089 _Toc232411962 _Toc259691668 _Toc232486697 _Toc232837417 _Toc232850544 _Toc232411963 _Toc232486698 _Toc232837418 _Toc232850545 _Toc259691669 _Toc206819308 _Toc232411964 _Toc206819319 _Toc232411965 _Toc232486699 _Toc232837419 _Toc232850546 _Toc259691670 _Toc259109534 _Toc259109535 _Toc259109536 _Toc259109537 _Toc259109538 _Toc259109539 _Toc259109540 _Toc259109541 _Toc259109542 _Toc259109543 _Toc259109544 _Toc259109545 _Toc259109546 _Toc259109547 _Toc259109548 _Toc259109549 _Toc259109550 _Toc259109551 _Toc259109552 _Toc259109553 _Toc259109554 _Toc259109555 _Toc259109556 _Toc259109557 _Toc259109558 _Toc259109559 _Toc259109560 _Toc259109561 _Toc259109562 _Toc259109563 _Toc259109564 _Toc259109565 _Toc259109566 _Toc259109567 _Toc259109568 _Toc259109569 _Toc259109570 _Toc259109571 _Toc259109572 _Toc259109573 _Toc259109574 _Toc259109575 _Toc259109576 _Toc259109577 _Toc259109578 _Toc259109579 _Toc259109580 _Toc259109581 _Toc259109582 _Toc259109583 _Toc259109584 _Toc259109585 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