ࡱ> 57./6` ; bjbj vX0$BmmmPnnBp2up8v8v8vwz |$h0%q~ww~~%8v8vooo~R8v8vo~oofp"58vp pUmGD[0I$55"W}"}o~~}}}%%j}}}~~~~BBB5<1BBB<BBB OHS Registration #:  FORMTEXT       Expiration Date:  FORMTEXT       STANDARD OPERATING PROCEDURE/APPROVAL FORM FOR CARCINOGENS AND HIGHLY TOXIC MATERIALS Instructions: Please complete this form to request approval to use and possess highly toxic or carcinogenic material from the University Chemical Hygiene Committee as required by Chapter 12 of the University Chemical Hygiene Plan and University Policy 7-37. Submit a separate form for each chemical. Copies of the current guidelines and Chemical Hygiene Plan are available at the DOHS web site: http://www.udel.edu/OHS/. For questions, please contact the University Chemical Hygiene Officer at 831-2103. Section I Information Principal Investigator(s):  FORMTEXT      E-Mail Address:  FORMTEXT      Department:  FORMTEXT      Address:  FORMTEXT      Phone Number:  FORMTEXT      Fax Number:  FORMTEXT      Lab(s) to be Used:  FORMTEXT      Chemical:  FORMTEXT Carbon Tetrachloride Section II Use and Storage A. Purchasing All purchases of this material must have approval from the Principal Investigator (PI) or authorized personnel before ordering. The user is responsible to ensure that a current Material Safety Data Sheet (MSDS) is obtained unless a current one is already available within the laboratory. Quantities of this material will be limited to  FORMTEXT      , and/or the smallest amount necessary to complete the experiment. B. Authorized personnel Please select the general categories of personnel who could obtain approval to use this material:  FORMCHECKBOX  Principal Investigator FORMCHECKBOX  Graduate Students FORMCHECKBOX  Undergraduates FORMCHECKBOX  Technical Staff FORMCHECKBOX  Post Doctoral Employees FORMCHECKBOX  Other (Describe):  FORMTEXT       Please list the specific personnel and their approval level (Attach an addendum to this form for additional personnel): NOTE: The Principal Investigator must be aware of all purchases of this material. The Principal Investigator must assure the there is not an exceedance of the quantity limits.  FORMTEXT       FORMCHECKBOX  Purchase FORMCHECKBOX  Use the Material FORMTEXT       FORMCHECKBOX  Purchase FORMCHECKBOX  Use the Material FORMTEXT       FORMCHECKBOX  Purchase FORMCHECKBOX  Use the Material FORMTEXT       FORMCHECKBOX  Purchase FORMCHECKBOX  Use the Material FORMTEXT       FORMCHECKBOX  Purchase FORMCHECKBOX  Use the Material The Principal Investigator will update this section when any personnel changes occur. If changes occur, document the changes (include the record of training of additional personnel) in the laboratories files and submit an addendum to the University Chemical Hygiene Officer with all training documentation. C. Storage Materials will be stored according to compatibility and label recommendations in a designated area. Please list compounds that this chemical is incompatible with:  FORMTEXT Becomes corrosive when in contact with water. Reacts violently with sodium metal , potassium metal , magnesium metal, alluminum metal, alkali metals, allyl alcohol and fluorine gas  Please list special storage requirements (I.E.: Refrigerated, Inert Atmosphere, Desiccated, etc.):  FORMTEXT Observe manufacturer's storing and handling recommendations. Store in a cool area and away from sunlight. Store in a well-ventilated area. No smoking, naked lights, heat or ignition sources. Store away from incompatible materials. Store away from foodstuff containers. Protect containers against physical damage. Keep containers securely sealed. Check regularly for spills and leaks.  Please list specific storage area (This Area Must be Marked and Labeled):  FORMTEXT       Storage areas will be inspected by laboratory personnel on a regular basis. Personnel will check for safety concerns such as improper storage, leaking/damaged container(s), damaged labels, quantities in excess of approved limits, theft/disappearance of material, etc. The inspector will also determine if an inventory reduction is possible. The Principal Investigator will designate one individual to complete this inspection. Please select an inspection frequency:  FORMCHECKBOX  Weekly FORMCHECKBOX  Biweekly FORMCHECKBOX  Bimonthly FORMCHECKBOX  Monthly D. Use location: Materials shall be used only in the following designated areas. Check all that apply:  FORMCHECKBOX  Demarcated Area in Lab (Describe):  FORMTEXT       FORMCHECKBOX  Fume Hood FORMCHECKBOX  Glove Box FORMCHECKBOX  Other (Describe):  FORMTEXT       Section III  Personnel Safety and Protection A. Training requirements: All users must demonstrate competency and familiarity regarding the safe handling and use of this material prior to purchase. The Principal Investigator is responsible for maintaining the training records for each user of this material. Training should include the following: Review of current MSDS Review of the OSHA Lab Standard Review of the Chemical Hygiene Plan Special training provided by the department/supervisor (Right to Know) Review of the departmental safety manual if applicable Safety meetings and seminars One-on-One hands-on training with the Principal Investigator or other knowledgeable laboratory personnel. B. Personal Protective Equipment: All personnel are required to wear the following personal protective equipment whenever handling this material: Proper Laboratory Attire (Pants or dresses/shorts below the knees, sleeved shirt, close-toe shoes) Safety Glasses Lab Coat Personnel may be required to wear other Personal Protective Equipment when working with this material. The Principal Investigator should contact the University Chemical Hygiene Officer to discuss the selection of chemical protective clothing (aprons, suits and gloves) and respirators. Please check all that apply:  FORMCHECKBOX  Chemical Safety Splash Goggles FORMCHECKBOX  Face Shield FORMCHECKBOX  Chemical Protective Gloves (Describe):  FORMTEXT Silver Shield, Polyvinyl Alcohol, Viton FORMCHECKBOX  Chemical Protective Clothing (Describe):  FORMTEXT       FORMCHECKBOX  Chemical Protective Splash Apron (Describe):  FORMTEXT       FORMCHECKBOX  Respirator (Type):  FORMTEXT       FORMCHECKBOX  Other (Describe):  FORMTEXT       C. Safe Work Practices The following safe work practices should be employed when using this material: Wear all required personal protective equipment Cover open wounds Wash hands thoroughly when work with the material is completed No mouth pipetting Use of sharps, such as glass Pasteur pipettes, needles, razor blades, etc. should be avoided or minimized Must not work alone in the laboratory Please list any other safe work practices:  FORMTEXT Avoid breathing vapours and contact with skin and eyes. Use in a well-ventilated area. Wear personal protective equipment when handling. Avoid smoking, naked lights or ignition sources. Avoid contact with incompatible materials. until atmosphere has been checked. Keep containers securely sealed when not in use. Avoid physical damage to containers. When handling, DO NOT eat, drink or smoke. Wash hands with soap and water after handling. Work clothes should be laundered separately: NOT at home.  D. Personnel Decontamination For most exposures, decontamination should occur as follows: Small Skin Exposures Wash contaminated skin in sink with tepid water for 15 minutes Have buddy locate the MSDS Wash with soap and water Contact Occupational Health and Safety at 831-8475 for further direction Eye Exposure Locate the emergency eye wash Turn eye wash on and open eyelids with fingers Rinse eyes for 15 minutes Have buddy contact 911 for the Newark Campus, 911 for all others and locate the MSDS Notify OHS Large Body Area Exposure Locate the emergency safety shower Stand under shower and turn it on Rinse whole body while removing all contaminated clothing Have buddy contact 911 for the Newark Campus, 911 for all others and locate the MSDS Rinse body for 15 minutes Notify OHS Please list any special decontamination procedures:  FORMTEXT       E. Exposure Symptoms and Treatment Please list the emergency procedures to be followed in the event of an exposure. These will be found in the MSDS for the compounds: Skin/eye contact: Symptoms:  FORMTEXT EYE: There is some evidence to suggest that this material can cause eye irritation and damage in some persons. The material may be irritating to the eye, with prolonged contact causing inflammation. Repeated or prolonged exposure to irritants may produce conjunctivitis. SKIN: Skin contact with the material may produce toxic effects; systemic effects may result following absorption. There is some evidence to suggest that this material can cause inflammation of the skin on contact in some persons. The liquid may produce skin discomfort following prolonged contact. Defatting and/or drying of the skin may lead to dermatitis. Toxic effects may result from skin absorption. Exposure limits with "skin" notation indicate that vapor and liquid may be absorbed through intact skin. Absorption by skin may readily exceed vapor inhalation exposure. Symptoms for skin absorption are the same as for inhalation. Contact with eyes and mucous membranes may also contribute to overall exposure and may also invalidate the exposure standard. The material may cause skin irritation after prolonged or repeated exposure and may produce on contact skin redness, swelling, the production of vesicles, scaling and thickening of the skin.  First Aid:  FORMTEXT Rinse with water in a emergency eye wash or safety shower while removing contaminated clothing for 15 minutes. Seek emergency medical care by dialing 911. Ingestion: Symptoms:  FORMTEXT Toxic effects may result from the accidental ingestion of the material; animal experiments indicate that ingestion of less than 40 gram may be fatal or may produce serious damage to the health of the individual.  First Aid:  FORMTEXT  If swallowed do NOT induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain open airway and prevent aspiration. Observe the patient carefully. Never give liquid to a person showing signs of being sleepy or with reduced awareness; i.e. becoming unconscious Give water to rinse out mouth, then provide liquid slowly and as much as casualty can comfortably drink. Contact 911 immediately.  Inhalation Symptoms:  FORMTEXT Toxic by inhalation. Vapours potentially cause drowsiness and dizziness*. The material is not thought to produce respiratory irritation (as classified using animal models). Nevertheless inhalation of the material, especially for prolonged periods, may produce respiratory discomfort and occasionally, distress. Anaesthetics and narcotic effects (with dulling of senses and odour fatigue) are a consequence of exposure to chlorinated solvents. Individual response varies widely; odour may not be considered objectionable at levels which quickly induce central nervous system effects. High vapour concentrations may give a feeling of euphoria. This may result in reduced responses, followed by rapid onset of unconsciousness, possible respiratory arrest and death.  First Aid:  FORMTEXT Move to fresh air. Seek emergency medical care by dialing 911. Provide CPR if necessary. Injection Symptoms:  FORMTEXT May be fatal First Aid:  FORMTEXT Seek emergency medical care by dialing 911. The ChemWatch MSDS, which is available at http://www.udel.edu/OHS/ oftentimes, has treatment information for Emergency Room Personnel and Doctors to follow. Please list any information that can be provided to assist with the treatment:  FORMTEXT  Acute exposures to carbon tetrachloride present, initially, with CNS depression followed by hepatic and renal dysfunction. Respiratory depression and cardiac dysrhythmias are an immediate threat to life. Since a major fraction of absorbed carbon tetrachloride is exhaled in first hour, good tidal volumes should be maintained in severely poisoned patients; hyperventilation may be an additional therapeutic modality. Ipecac syrup, lavage, activated charcoal or catharsis may all be used in the first 4 hours. Since reactive metabolites may cause hepatorenal toxicity, administration of N-acetyl-L-cysteine may reduce complications. Experience with this therapy is limited. [Ellenhorn and Barceloux: Medical Toxicology]. . * Preplacement and annual medical examinations are recommended for workers exposed to carbon tetrachloride. Preplacement examinations should include an evaluation of alcohol intake, a urinalysis that includes a microscopic examination, and kidney function tests. Special attention should be given to the central nervous system, the skin and blood. Individuals with kidney, liver or central nervous system disorders or who are alcoholics should not be exposed to carbon tetrachloride. (Source: Occupational Diseases) Note: Consumption of alcohol augments the injurious effects of this substance. (I.L.O.) F. Spills The laboratory should be prepared to clean up minor spills (25 ml/25 g or less) of highly toxic/carcinogenic materials should they occur in a properly operating fume hood. Chemical spill clean up guidance can be found at http://www.udel.edu/OHS/chemspillkit/chemspillkit.html. Laboratory personnel cleaning up a spill will wear all personal protective equipment listed above and manage all cleanup debris according the waste disposal section. Notify OHS of any spills, even if the lab staff handled the clean-up. Please list the following: Location of Spill Cleanup Materials for a small spill:  FORMTEXT       Any special measures/cleanup material required to cleanup a spill:  FORMTEXT Clean up all spills immediately. Wear protective clothing, impervious gloves and safety glasses. Avoid breathing vapours and contact with skin and eyes. Remove all ignition sources. Wipe up and absorb small quantities with vermiculite or other absorbent material. Place spilled material in clean, dry, sealable, labelled container.  If a spill is large or occurs outside of a fume hood, the laboratory occupants should immediately vacate the laboratory, close all doors and contact Occupational Health & Safety at 831-8475 during working hours or 911 after hours. If the laboratory personnel determine that the spill is not contained to the lab or could cause harm to people outside the laboratory, they should pull the building fire alarm and go to the Emergency Gathering Point to await the University Police and Emergency Responders. The responsible/knowledgeable person should provide the University Police and the Emergency Responders with the following: Common Name of the Material Involved A copy of a MSDS, if possible Any pertinent information related to the emergency, such as location in the lab, other hazards in the lab, etc. G. Emergency Phone Numbers: Below are a list of emergency numbers to contact in the event of an emergency: Police, Fire or Medical Emergency, call 911 on the Newark Campus, 9-911 for all others Occupational Health & Safety X8475 Please provide a list of other emergency phone numbers, such as after hour contacts for laboratory personnel or any other important phone number, to be used in the event of an emergency:  FORMTEXT       H. Other Special precautions Please list any other special precautions or procedures not listed in the above sections. Please be as specific as possible:  FORMTEXT  CHRONIC HEALTH EFFECTS Cumulative effects may result following exposure*. There has been concern that this material can cause cancer or mutations, but there is not enough data to make an assessment. This material can cause serious damage if one is exposed to it for long periods. It can be assumed that it contains a substance which can produce severe defects. This has been demonstrated via both short- and long-term experimentation. Primary routes of exposure include inhalation, accidental ingestion and skin absorption. The material may accumulate in the human body and progressively cause tissue damage. Chronic exposure may cause liver, heart and kidney damage. Enlarged and tender liver, and jaundice may result from toxic hepatitis. Diminished urinary volume, red and white blood cells in urine, coma and death may be consequences of acute renal failure. Chronic exposure may also cause visual disturbances such as haze, blind spots, narrowing of visual field. The hazard of systemic effects is increased when carbon tetrachloride is used in conjunction with ingested alcohol. When administered by gavage, carbon tetrachloride increased the incidence of hepatomas and hepatocellular carcinoma in mice of both sexes. When administered by inhalation carbon tetrachloride induced liver carcinomas in rats. Three case reports describe liver tumors associated with cirrhosis in humans exposed to carbon tetrachloride. A mortality study of laundry and dry cleaning workers exposed to a variety of solvents suggested an excess of respiratory cancers, liver tumors and leukemia.  Section VI Waste Disposal The authorized person using this material is responsible for the safe collection, preparation and proper disposal of waste unless otherwise stated below. Waste shall be disposed of as soon as possible and in accordance with all laboratory and University procedures. All personal must obtain chemical waste disposal training via DOHS. Specific instructions:  FORMTEXT  Collect solid waste material in a 7mil polyethylene bag and label with an orange chemical waste label. Collect liquid waste in a "Justrite" container provided by DOHS. Label with a hazardous waste label. Use proper laboratory ventilation such as a fume hood to manage both liquid and solid wastes. Contact DOHS for removal. Do not put in the normal trash or pour any solutions down the drain.  Section V Signature and Verification Your signature b(*>@BLNPvxP R p / 0 8 P \ g { | } ½{tm h1|5>* h3 h2ho:h3 h3 >*hw h3 5h3 h1| h25 hl5h8h*5>*!jvh8h 5>*U h*5h8h1|5>*jhr65>*U!jh8h 5>*U h85>*jh85>*U h1|5&PRN P R  & F$Ifgd3 @&gdv&$d%d&d'dNOPQgd2gd3 $a$ $@&a$gdv$a$gd1| $@&a$gdv7 :   2 4 H J L V X \ v x  ڸҤښڴҊښ{k{jh3 h3 >*U h3 >*jh3 >*UjhvhmQ>*Ujhr6>*UjhvhmQ>*Uhwjho:>*UjhvhmQ>*Uhvhv>*jhvhv>*Uh3 h1| hnc5>*h1|h1|5>*%  Z \ ikd>$$Ifl,"\ t0644 la< & F$Ifgd3 ikdb$$Ifl,"\ t0644 la<\ ikd$$Ifl,"\ t0644 la< & F$Ifgd3  $ f & F$Ifgd3 ikd$$Ifl,"\ t0644 la<   " > @ T V X b d h    )*+:;ؿӯث؃yrkd\hh5 h5>* h3 5>* hnc5>*hh5>*hl hUl>>*jhhl>*U h>*jh>*Uhjh3 hl>*Uh Ijh3 hl>*U h3 >*h3 jhr6>*Ujh3 >*UjZh3 h3 >*U$f h u & F$Ifgd3 |kdB$$Ifl0,"L t0644 la<  ikd $$Ifl,"\ t0644 la< & F$Ifgdikd2$$Ifl,"\ t0644 la<  *+:;,p & F$Ifgd*^gd @&^gdvgd@&gdvh^hgd;pOP[\  ,.JLNnrt~sj h*Ujh*Uh*jh*UjZhV`UjhV`UjhU h5hh5 hnc5hjhr6>*Ujrhhl>*Uhh>*jhh>*Uhhl-pr|&Ukd $$Ifl0D D"t  tt644 la< & F$Ifgdl & F$Ifgd*hkdB $$IflFL D"| | | tt6    44 la<.02\^rtvz  (*ξӯӧ裟oe]RjO hV`UjhUUjhr6>*Uj hUhl>*U hU>*jhU>*Uh0< h0<5h0<h0<5hUhhUh*>*jh*>*UmHnHuj hUh*>*U h*>*jh*>*Ujf h*Uh*jh*UjQ hV`U xz B $Ifgd & F$IfgdU^gd $^a$gd*BkdN $$IflD"t tt644 la< & F$Ifgd* *,BD`bd  68LNPZ\^`|~޿ٙ޿sjhUhU>*UjhV`UjhUUjhUhU>*UjhV`Uj1h$QQUjhr6>*UjhUhU>*U hU>*jhU>*Uj hV`UhUjhUU-4obYY $Ifgdl & F$IfgdUkd7$$IflFr,"Ft t06    44 la<46^obYY $Ifgdl & F$IfgdUkd$$IflFr,"Ft t06    44 la<@obYY $Ifgdl & F$IfgdUkd$$IflFr,"Ft t06    44 la< &(*@B^`b  4!Cŵ蛗zvrnh Ihlhhh5 hnc5 h5 hnchhah0<hncjKhV`UjhUUjahUhU>*U hU>*jihV`UjhUUjhUUhUjhU>*Ujhr6>*U+2obYY $Ifgdl & F$IfgdUkd$$IflFr,"Ft t06    44 la<246DEof\f\Z\f @&^gdv^gdkd$$IflFr,"Ft t06    44 la<CDIJL|~.02<>@BXn  ? @ N!O!P!V!a!ϳϕ{{ws{hnchvhwhUh Ihh>*jhr6>*Uj/hhhl>*Ujhh>*Uh'YhhhUl>hUl>>*jh Ihl>*U hh>* hUU>*jCh Ihl>*U h I>*jh I>*Uh Ihl-EKL@BO!P!x!y!!! $Ifgdwgdw & F ^gdh^gdh^gd & F ^gdh & F ^gd`%8^8gdh & F ^gdz a!x!y!z!!!!!!!!!!!!!!!!!!!!!!!!!V"x"|"""""""##2#4#6#qjhhhl>*U hh>*jhh>*UjYhV`UjhhUhUhhhU5hhhh5 hnc5hhjuhV`Ujh'YUjh'YUjh'YUh'Yjh'YUhwh I)!!!!yy $Ifgdw|kd$$Ifl0D t t t0644 la<!!!!!~""""ysnd[[[^gdh @&^gdvgdU@&gdv^gd|kd$$Ifl0D t t t0644 la<6#@#B#F#H#d#f#h###########$ $$ $"$,$.$4$J$$$$$$$$$$%A&Q&T&''/'\'캪蔍zrnnhhhhl5 hh5hlhhhh5>* hnc5>* hk5>*jhh>*UmHnHujyhhhh>*U hh>*jhhUjhlUjhLUjhhUhhjhh>*Ujhr6>*U+"D#F###ikdC$$Ifl,"\ t0644 la< & F$Ifgdh##0$u & F$Ifgdh|kd$$Ifl0~," t0644 la<0$2$4$$$$${&|&&&&&&zrrr & Fgdh @&^gdv@&gdv^gdhikd$$Ifl,"\ t0644 la< &&%'&']'^'{'|''' ( ({(|(((((((7*8*^gd]Pgd]P8^8gd]P & Fgd]P8^8gdh & Fgdh^gdh\'{'|''''''''( (y(z({(((7*8*9*G*H*I*j*k*y*z*{***************** + + +޼ޱާuj hmQUh]Ph]P>* hUl>>* hn>*j h]Phl>*U h]P>*jh]P>*Ujh=]Ujh]PUjUh$QQUjh]PUh'h]P hw5hhhl5 hh5hwhhhl.8*j****u|kdA$$Ifl0~," t0644 la< & F$Ifgd***,,ikd!$$Ifl,"\ t0644 la< & F$Ifgd*ikd $$Ifl,"\ t0644 la< +9+:+D+E+, , ,,,,.,0,2,,,,,,,,,,,,, - - -"-$-.-0-2-4-6-yjbZjh*Uh*h]P>*jh*>*UmHnHuj#h*hl>*U h*>*jh*>*Ujm#hlUj"h]Ph]P>*Uj)"h]PUjh]PUh]Ph]P>*jh]P>*UmHnHuj[!h]Phl>*U h]P>*jh]P>*Uh]P#,,,2-ikd#$$Ifl,"\ t0644 la< & F$Ifgd*2-4---ikd%$$Ifl,"\ t0644 la< & F$Ifgd*ikdY$$$Ifl,"\ t0644 la<6-R-T-V-d-z------------3/@/A/B/g/h//////1111111111۷ۯ{snindn`h2 hl5 h'5 h(5hUl>hUl>>*j%hh>*U h>*jh>*Uh'Yh'h h5hlh*h*>*jh*>*UmHnHuj'%h*hl>*U h*>*jh*>*Uh(jh*Uj$hlUh*%---->.?.o.p.......A/B/h/i/111111^gd( & Fgdn8^8gd'8^8gd & Fgd^gd11122#222222233363B3Q3p333333~444(5\5r555555666 6 66R6T6V6x6666\7b7777ַ֯ hJ>*jhJ>*Uh(hl5 h'5 h5 h(5hlhh>*jhu>*Ujk&hh>*U h>*jh>*Uhhuh" h fh17h'h2h(31 2 2L2g2222222(3B3333333 4~4(5\5r5 & Fgdu & Fgd f^gd2 & Fgd28^8gd2 & Fgd2r5t56 6T6V6`7b777<a=b=m=n=\>]> & F   ^ gdJp^pgd( & F   ^ gd( & F   ^ gdUl>^gd( & F ^gd(^gd(@&gdvgd777778888<<<<<<<<<"=]=^=_=`=y=z====Z>[>\>i>j>t>u>v>ؿ滱}un^jC(h(h(>*U h(h(hUl>hUl>>*j'h(h(>*U hn>* h1I>* h4>*jW'h(hl>*U h(>*jh(>*Uh(h`%h`%>*mHnHuhUl>>*mHnHuhUl>hUl>>*mHnHujhJ>*Uj&hJh&b>*U#v>>>/?1?O?P???+@C@E@F@S@_@`@j@k@l@gChCiCvCwCCCCCCCCCDDDDDDDD(D)D*D/D8DֲֹѢ֖֝цֲ֝v֝q h(E>*j*h(h'>*Uj)h(h'>*U h'h' h4>*j/)h(h'>*U h(h'hUl>hUl>>*j(h(h'>*U h'>*jh'>*Uh'h(jh(>*U hn>*hnhn>*,]>G@H@S@T@iCjCCCCCDDWDXDTEUE^gd" p^pgd( & F   ^ gd'p^pgd' & F   ^ gdJ^gd' & F ^gd(^gd( & F   ^ gdn8DUDVDWDDDDDDDFEGEQERESEUEJJJJJJJJJJJJJJJNKKKKKK?LLȫș蔏{wwswswogowwchuhThT>*hThvhf h(h( hl5h(hl5 h(5 h5h(EhUl>hUl>>*mHnHu h" >*j*h?#hpD>*Uh?#h?#>*jh?#h?#>*Uh hhh(h(>*h(h'jh'>*U h4>*&UEE'FF^GH4H6HHHI_IIIJ:J~JJJJJJLLL^gdf^gd(p^pgd(^gd4^gdUl>LLNNPPSSDSEScSdSSSSSBTCTTT & F ^gdnc^gdnc8^8gd2 & Fgd2^gd( & Fgd`%8^8gdf & Fgdf^gdfLLLMMN N NNNNNNNPPPQ0QQQQQQ\R{R|R}RRRSSSSSSSSCTITSTdTjTmTqTTTTTU(Uh fh(hUu&h!hnchl56>*hnchl5hnchnc5 h5hlh2h'hUl>hUl>>*j}+hfh>*Ujhr6>*Uj+hfhf>*U hf>*jhf>*Uhf2TTTVVVNVPVjWlWWkY]]^^U_V_|_}_ aaaa^gdkgdk@&gdv^gdUl>^gdnc & F ^gdnc(U1UHUTUUUUUUUV V VVVVVLVNVPV^VhVnVVVVVWWJWNWPWdWfWhWlWnW]]]]]¾|tjhkhnc5>*h!hl>*hUl>hUl>>*h`%h`%>* h1I>*ji,h!hl>*Uh2 h!hlh!hl5 hnc5 h5hlh!h!>*jh!>*UmHnHuj+h!hl>*U h!>*jh!>*Uh'h!(]^^^B_K_T_m_n_o_y_z_{_}_ aaaaaaaa"a*UjU-hlhl>*U hl>*jhl>*UhlUh! hk5>*hkhnc5>*hkh!5>* hr6>* hVz>*htHhtH>* h1I>*j,hfh>*U hf>*jhf>*Uhfhah'Yhk hnc5>*hkhk5>*#aaaa=a>a>@}p $If^gdlUkdA.$$Ifl0d $ t"644 la$If & F$Ifgdlgd_AK^gd "68:DF35yrje` h!5 hRWQ5h!h!5 hl5>* hk5>* hRWQ5>*h!h!5>* hK5>* h!5>* hlhlj/hlhl>*Ujm/hlhl>*Uhlhl>*jhl>*UmHnHuj-hlhl>*U hl>*jhl>*Uhl%HJSF $If^gdlUkdY0$$Ifl0d $ t"644 la$If & F$IfgdlBkd.$$Ifld$" t"644 la45_`D$If & F$IfgdRWQ @&^gdv@&gdv^gdkBkd0$$Ifld$" t"644 la 5^_`qr|} 246@BDF-CDNO 2׳ң׳כ喎z׳jS3hRWQhRWQ>*Uhnch!hRWQ5 hRWQ5hRWQhl>*j1hRWQh>*UjhRWQ>*UmHnHuj1hRWQh>*U hRWQ>*jhRWQ>*UhRWQhl h!h!h'h!h!>*h!/DFu $If^gdRWQ|kdq2$$Ifl0d $ t0"644 la56Dul $Ifgd & F$Ifgd @&^gdv^gdkikd2$$Ifld$" t0"644 la246@BF=>9:DE (*>@BLNR˿˳˯yiyahnchRWQ5j6hRWQhk>*UhRWQhk>*jhk>*UmHnHuj!5hRWQhk>*U hk>*jhk>*Uhkhnch!hRWQ5 hRWQ5 hRWQhRWQhRWQhRWQhRWQ>*jhRWQ>*UmHnHujhRWQ>*Uj3hRWQhRWQ>*U#DFu $If^gd|kd?4$$Ifl0d $ t0"644 la2ul $Ifgd & F$Ifgd @&^gdv^gdkikd4$$Ifld$" t0"644 laPu $If^gdk|kd5$$Ifl0d $ t0"644 laPRikd6$$Ifld$" t0"644 la $If^gdikd6$$Ifld$" t0"644 la>? $If^gd! $$Ifa$gd!gd $@&a$gd @&^gdv^gdk,AC$'=>?C\   *+56ŽjhHUhmQhmHnHujhvUhvhHhQtmHnHuh/ajh/aUhpjhpUhlU h;h h5hhnch'h'YhRWQhnchl56xkZk & F$If`gd! $If^gd! $$Ifa$gd!zkdU7$$Ifl0 6$  t0644 laxkZk & F$If`gd! $If^gd! $$Ifa$gd!zkd7$$Ifl0 6$  t0644 laefxkZk & F$If`gd! $If^gd! $$Ifa$gd!zkd8$$Ifl0 6$  t0644 lathe University Chemical Hygiene Committee to review the approval form and the use of the material. ______________________ Submit (via campus mail) the completed and signed form back to the University Chemical Hygiene Officer for conditional approval to purchase and use the material. The University Chemical Hygiene Committee will review this form at the next scheduled meeting for full approval. ______________________ Complete a Job Hazard Analysis (JHA) for each experiment in which this compound is used. These JHAs must be kept on file in the laboratory and updated every 5 years or when a process changes. ______________________ Provide and document training for every worker who will use the material. Training shall include hands-on instruction as well as review of the JHA, SOP and the University Chemical Hygiene Plan; specifically Chapter 12. ______________________ Conduct a trial run with OHS present. ______________________ Have OHS present the first time a process using this material occurs.       DATE \@ "MM/dd/yyyy" 07/21/2005  PAGE 2 Page  PAGE 1 of  NUMPAGES 10  PAGE 1  DATE \@ "MM/dd/yyyy" 07/21/2005 fg~xkZk & F$If`gd! $If^gd! $$Ifa$gd!zkd~8$$Ifl0 6$  t0644 lanoxkZk & F$If`gd! $If^gd! $$Ifa$gd!zkd8$$Ifl0 6$  t0644 laopdexkZk & F$If`gd! $If^gd! $$Ifa$gd!zkdH9$$Ifl0 6$  t0644 laef}~xkZk & F$If`gd! $If^gd! $$Ifa$gd!zkd9$$Ifl0 6$  t0644 laxkZk & F$If`gd! $If^gd! $$Ifa$gd!zkd:$$Ifl0 6$  t0644 la     }}}}}}}}{}s$a$gdHgd~Fzkdw:$$Ifl0 6$  t0644 la             ( ) 3 4 5 6 7 ; пڵڙhlhp hhhQt0JmHnHu h0Jjh0JUhUl>0JmHnHu h~F0Jjh~F0JUhhmQhnmHnHuhHmHnHujhHUhH    5 6 7 8 9 : ; gd~Fgd 90&PP:p'> Comment ReferenceCJ44  Comment Textj@#j 3 Table Grid7:V04@24 Header  !4 @B4 Footer  !HRH  -3 Balloon TextCJOJQJ^JaJ.)@a. - Page NumberYRY;()OP|<=[\'(LMw HIJvw ! 5 Q u v  ! V W c d &'56Snop()Fcd<=bclmefuv)*ef  ;<NO 45bc3Lcno ` z |!}!!!w&-'.'9':'(()(*** *5-6-------#.$. /!///0*1122M222+3w3334J4_4`4a4l4m4q6r66666z8{8::;;6;7;;;;;<<o<p<<<g=h=i===>>.>?EDFDdDeDEEEEmGnGoGpGqGrGuGGGHHHHH I I7IRISIIIIIIIII KK3KNKOKKKKKKaMbMMMMMMMMMvOwOOOOOO&P'P(P@PAPRRLRMRSSSSSSSSSSFTGTHT_T`TTTTTT'U(U)U@UAUUVVVWVnVoV0W1W2WIWJW&X'X(X?X@XfXgXhXXXXXXXXXXXXXXXYYYYYYYYYYYY0000)00P0P0P0P0P0P0P0P00 0 0  0 0  0 0 0 0 0  0 0  0 0 0 0 00000000000 0 0 0 0  0  00 0 0 00000 0 0 0 0  0 0 0 0  0 0 0 0  0 0 00  0 0 0 0 000! 00W 00d 0d 0d 0d 0d 0d 0d 0d 0d 0d 0d 0d  0d  0d  0d  0d  0d  0d 00p0000 00  0 0 0  0 0 0000000 00 00 00 00 00 00 000000 00 00 0000 0  0 0  0 0  0 0  0 0  0 0  0 0 00000 00 00 00 00 00 00 000000 00 0 0 0 00 00 0 0 0 0 00 00 0 0 0 0 0 0000 0 0 0 0  0 0  0!  0 0 00 0{&0 0{&0 00 0a)0 0a)0 00 0,0 0,0000000000000000000000000000 00 0000 00 00 000000 00 000000000000000C0C0C0C0C0C0C0C0C0C0C0C0C0C0C0C 0C 0C 0C 0C 0C  0C 0C 0C 0C 0C 0C0C00H00H0H0H 0H 0H 0H 0H 0H 0H00J0J0J 0J 0J 0J 0J 0J 0J00)M0)M0)M 0)M 0)M 0)M 0)M 0)M 0)M 0)M 0)M00uO0uO0uO00NQ0NQ0NQ0NQ0NQ0NQ0NQ 0NQ 0NQ 0NQ 0NQ 0NQ0NQ 0NQ 0NQ 0NQ 0NQ0NQ 0NQ 0NQ 0NQ 0NQ0NQ 0NQ 0NQ 0NQ 0NQ0NQ 0NQ 0NQ 0NQ 0NQ0NQ 0NQ 0NQ 0NQ 0NQ0NQ 0NQ 0NQ 0NQ 0NQ0NQ 0NQ 0NQ 0NQ 0NQ0 0 0@0ي00@0ي00@0ي00@0ي00@0@0@0@0@0@0@0@0ي00 00ي06()OP|<=[\'(LMw HIJvw ! 5 Q u v  ! V W c d &'56Snop()Fcd<=bclmefuv)*ef  ;<NO 45bc3Lcno ` z |!}!!!w&-'.'9':'(()(*** *5-6-------#.$. /!///0*1122M222+3w3334J4_4`4a4l4m4q6r66666z8{8::;;6;7;;;;;<<o<p<<<g=h=i===.>EDFDdDeDEEGGHHHHH I I7IRISIIIIIIIII KK3KNKOKKKKKKaMbMMMMMMMMMvOwOOOOOO&P'P(P@PAPRRLRMRSSSSSSSSSSFTGTHT_T`TTTTTT'U(U)U@UAUUVVVWVnVoV0W1W2WIWJW&X'X(X?X@XfXgXhXXXXXXY0000)00P0P0P0P0P0P0P0P00 0 0  0 0  0 0  0 0  0  0 0  0 0  0 0 00000000000 0  0  0 0  0  0 0  0 0 00000 0 0 0 0  0 0 0 0  0 0 0 0  0 0 0 0  0 0 0 0 000! 00W 00d 0d 0d 0d 0d 0d 0d 0d 0d 0d 0d 0d  0d  0d  0d  0d  0d  0d 000000 0 0  0  0 0  0 0 0000000 00 00 00 00 00 00 000000 00 00 0000 0  0 0  0 0  0 0  0 0  0 0  0 0 00000 00 00 00 00 00 00 000000 00 0  0  0  0 0 00 0 0 0 0 00 00 0 0 0 0 0 00000000 00 0  0 0 00 0{&0 0{&0 00 0a)0 0a)0 00 0,0 0,0000000000000000000000000000 00 00?0?0? 0?0? 0?0? 0?0?0?0?0?0? 0?0? 0?0?0?0?0?0?0?@00?0? 00'0'0' @00)0)0) 0) 0) 0) 0) 0)  0) 0) 0) 0) 0) 0)0) 00+ 00+0+0+ 0+ 0+ 0+ 0+ 0+ 0+ 00-0-0- 0- 0- 0- 0- 0- 0- 00/0/0/ 0/ 0/ 0/ 0/ 0/ 0/ 0/ 0/ 0072072072 00404040404040404040404 0404040404 0404040404 040404 0404 040404 0404 040404 0404 040404 04 04 0404 04 04 04 04C0&0'ğ2K00H: K00l  /2  ;*Ca!6#\' +6-17v>8DL(U]52; 148<>@DGILQTWY\]_bderux~ \ f p42E!!"#0$&8**,2--1r5]>UELTaDDPfoe ; 25679:;=?ABCEFHJKMNOPRSUVXZ[^`acfstvwyz{|}: 3 &;GM(4:GSYkw}yM]w4@Fw ! - 3 5 E Q a v  7 C $)6FSc &)9FVdt KW!'*:Q]cfvam` !!u&&&+'E'Q'&(5(A(*+*7*3-B-N-------!.//]46667+7x8S=_=e=>>CDEEsGHHHHHH#I/I5I>IJIPIK+K1K:KFKLKoM{MMMMMOOOOOOYFFFFFFFFFFFG$G$G$G$G$G$FFG G FG$G$FG$G$FG$G$FG$G$FFFG$G$G$G$G$FG$G$G$FG G$G FG$FG$FG FG FFFFFFFFFFFFFFFFFFFFFFFFFFF #. !,2!!!8@0(  B S  ?YAText43Text44Text47Text46Text45Text3Text4Text5Text6Text7Text8Check1Check2Check5Check4Check3Check6Text9Text10Check7Check8Text11Text12Text13Text14Text15Text16Text19Check20Check21Check23Check22Check9Text20Check10Check11Check12Text21Check13Check15Check17Text23Check16Text22Check14Check18Text24Check19Text25Text41Text40Text49Text27Text48Text38Text39Text29Text30Text37Text31Text32Text33Text34Text36Text35<)HlzNx5x" w 8 7T*GeL+Rgb !&/6 7T=>EHH$I?I K;KY  !"#$%&'()*+,-./0123456789:;<=>?@'N;Z~^G4 %*Gd':Wu!;dwa v&,'^46y8f=DDtGHH6IQI2KMKY!dYY9*urn:schemas-microsoft-com:office:smarttagsState9*urn:schemas-microsoft-com:office:smarttagsplace TFS] z~M*T*o+{+++,,,,77d8l8jBpBBBBBEFbFjFpTuTVVVVWWXXXXXXXXXXXXYYYvySX&&@@XXXXXXXXXXXXYYY33333 D xn`!t&R'&(8*3-!/]4,7x8>CDXXXXXXXXXXXXYYYYYYYYYYYYYY XXXXXXXXXXXXYYY"[DA'ZF\$M Q 0 # .- pmAb;2!xUcH&v$$'b+ C-m3D?(%bC$:n$Rx*moS&uOCT`?LXA*:$XhZֶ̿}5[;oS6\- Cla;2;mnOsUhE+u2i-8]udqKWv*<TyKk|h88^8`.h ^`hH.h  L ^ `LhH.h   ^ `hH.h xx^x`hH.h HLH^H`LhH.h ^`hH.h ^`hH.h L^`LhH.h^`.h ^`hH.h pLp^p`LhH.h @ @ ^@ `hH.h ^`hH.h L^`LhH.h ^`hH.h ^`hH.h PLP^P`LhH.hhh^h`.h 88^8`hH.h L^`LhH.h   ^ `hH.h   ^ `hH.h xLx^x`LhH.h HH^H`hH.h ^`hH.h L^`LhH. hh^h`hH) ^`hH) 88^8`hH) ^`hH() ^`hH() pp^p`hH()   ^ `hH. @ @ ^@ `hH.   ^ `hH.h^`.h ^`hH.h pLp^p`LhH.h @ @ ^@ `hH.h ^`hH.h L^`LhH.h ^`hH.h ^`hH.h PLP^P`LhH. ^`hH Article . 8^`hH Section . P^`PhH() `p`^``phH() P^`PhH) P^`PhH) ^`hH) P^`PhH. 0p0^0`phH.h^`.h ^`hH.h pLp^p`LhH.h @ @ ^@ `hH.h ^`hH.h L^`LhH.h ^`hH.h ^`hH.h PLP^P`LhH.h^`.h ^`hH.h pLp^p`LhH.h @ @ ^@ `hH.h ^`hH.h L^`LhH.h ^`hH.h ^`hH.h PLP^P`LhH.h^`.h pp^p`hH.h @ L@ ^@ `LhH.h ^`hH.h ^`hH.h L^`LhH.h ^`hH.h PP^P`hH.h  L ^ `LhH.^`. ^`hH. pLp^p`LhH. @ @ ^@ `hH. ^`hH. L^`LhH. ^`hH. ^`hH. PLP^P`LhH.h^`.h pp^p`hH.h @ L@ ^@ `LhH.h ^`hH.h ^`hH.h L^`LhH.h ^`hH.h PP^P`hH.h  L ^ `LhH. hh^h`hH. P^`PhH.. ^`hH... x^`xhH.... ^`hH .....  X ^ `XhH ......   ^ `hH.......  8^`8hH........  `^``hH.........h^`.h pp^p`hH.h @ L@ ^@ `LhH.h ^`hH.h ^`hH.h L^`LhH.h ^`hH.h PP^P`hH.h  L ^ `LhH.hhh^h`.h 88^8`hH.h L^`LhH.h   ^ `hH.h   ^ `hH.h xLx^x`LhH.h HH^H`hH.h ^`hH.h L^`LhH.h^`.h ^`hH.h pLp^p`LhH.h @ @ ^@ `hH.h ^`hH.h L^`LhH.h ^`hH.h ^`hH.h PLP^P`LhH.hhh^h`.h 88^8`hH.h L^`LhH.h   ^ `hH.h   ^ `hH.h xLx^x`LhH.h HH^H`hH.h ^`hH.h L^`LhH.^`. ^`hH. pLp^p`LhH. @ @ ^@ `hH. ^`hH. L^`LhH. ^`hH. ^`hH. PLP^P`LhH.hhh^h`.h 88^8`hH.h L^`LhH.h   ^ `hH.h   ^ `hH.h xLx^x`LhH.h HH^H`hH.h ^`hH.h L^`LhH.hhh^h`.h 88^8`hH.h L^`LhH.h   ^ `hH.h   ^ `hH.h xLx^x`LhH.h HH^H`hH.h ^`hH.h L^`LhH.hh^h`. 88^8`hH. L^`LhH.   ^ `hH.   ^ `hH. xLx^x`LhH. HH^H`hH. ^`hH. L^`LhH.h^`.h pp^p`hH.h @ L@ ^@ `LhH.h ^`hH.h ^`hH.h L^`LhH.h ^`hH.h PP^P`hH.h  L ^ `LhH.h^`.h ^`hH.h pLp^p`LhH.h @ @ ^@ `hH.h ^`hH.h L^`LhH.h ^`hH.h ^`hH.h PLP^P`LhH.h^`.h pp^p`hH.h @ L@ ^@ `LhH.h ^`hH.h ^`hH.h L^`LhH.h ^`hH.h PP^P`hH.h  L ^ `LhH.h^`.h ^`hH.h pLp^p`LhH.h @ @ ^@ `hH.h ^`hH.h L^`LhH.h ^`hH.h ^`hH.h PLP^P`LhH.h^`.h pp^p`hH.h @ L@ ^@ `LhH.h ^`hH.h ^`hH.h L^`LhH.h ^`hH.h PP^P`hH.h  L ^ `LhH.h^`.h ^`hH.h pLp^p`LhH.h @ @ ^@ `hH.h ^`hH.h L^`LhH.h ^`hH.h ^`hH.h PLP^P`LhH.hh^h`. 88^8`hH. L^`LhH.   ^ `hH.   ^ `hH. xLx^x`LhH. HH^H`hH. ^`hH. L^`LhH.h^`.h pp^p`hH.h @ L@ ^@ `LhH.h ^`hH.h ^`hH.h L^`LhH.h ^`hH.h PP^P`hH.h  L ^ `LhH.hhh^h`.h 88^8`hH.h L^`LhH.h   ^ `hH.h   ^ `hH.h xLx^x`LhH.h HH^H`hH.h ^`hH.h L^`LhH.h^`.h pp^p`hH.h @ L@ ^@ `LhH.h ^`hH.h ^`hH.h L^`LhH.h ^`hH.h PP^P`hH.h  L ^ `LhH.h^`.h ^`hH.h pLp^p`LhH.h @ @ ^@ `hH.h ^`hH.h L^`LhH.h ^`hH.h ^`hH.h PLP^P`LhH.Q Os"[qKWvhE+uAb}5[ Clak|C-%bCoS6\moSCThZTy'Z:$XcH&ALX$R3D?-8]u2!2;m$'b+$M .-                                                                                                                                                                                                                                          Y g` g`{zwD3 |b " Z r60<I!bzv&mQ'8k1Uck !: !p!?#Uu&B , -34E5C8o:Ul>#?pD(E~F~HtHJ_AKM!Nlo2/a(Jbp!-a IM8L*l6a?pnHV`nc&17*ty^JCXf`%TT<=[\Mw HIw ! 5 Q u v  56Sno()Fcd)*efHHHH I I7IRISIIIK3KNKOKKKbMMMMMMwOOOOOO&P'PAPSSSSSSSGTHT_TTTT(U)U@UVVWVnV1W2WIW'X(X?XgXhXXXXXXXXXYYYYYu^0u^0@ \F l !67`=`>GI,K,L|M|NOPTYPP@P P@PPPP4@PP@@P"P$PL@P,P\@P4Pp@PNP@PVP@PP@PP@PP@PP@P@UnknownGz Times New Roman5Symbol3& z Arial5& zaTahoma"1hCW[f@ K-@ K-!4dXX 2QHX?Uu&*STANDARD OPERATING PROCEDURE Kelly Morgan k_eichinger                          Oh+'0   @ L X dpx STANDARD OPERATING PROCEDURE Kelly MorganNormal k_eichinger3Microsoft Office Word@@*}+@Zm@ҮP@ K՜.+,0 hp  University of Delaware-X STANDARD OPERATING PROCEDURE Title  !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_`abcdefghijklmnopqrstuvwxyz{|}~      !"#$%'()*+,-2Root Entry FPDU4Data :1TableJWordDocumentvSummaryInformation(DocumentSummaryInformation8&CompObjq  FMicrosoft Office Word Document MSWordDocWord.Document.89qRoot Entry F.:@Data :1TableJWordDocumentv      !"#$%98 SummaryInformation(DocumentSummaryInformation8CompObjq  FMicrosoft Office Word Document MSWordDocWord.Document.89q՜.+,D՜.+,\ hp  University of Delaware-X STANDARD OPERATING PROCEDURE Title4 $,