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H,  @`e _!!0" l&l& l&t t !!C"l& : Review: Human Body Systems Vocabulary Cell: smallest unit of living things Tissue: a bunch of cells working together to do the same job Organ: a bunch of tissues working to do the same job Organ system: a bunch of organs working together to do the same job Organism: a group of organ systems working together to help an individual maintain homeostasis Processes of Life homeostasis: balanced internal environment metabolism: the rate at which food is broken down into energy nutrition: intake of organic molecules to supply essential materials for survival digestion: breaking down food to simple sugars (from starches) so it can enter the cells respiration: making energy from oxygen and food OR the act of exchanging oxygen for carbon dioxide circulation: movement of essential materials and wastes through the body excretion: removal of all waste products made by the cells movement: locomotion or movement from place to place coordination: send and respond to chemical messages and electrical impulses to keep the body moving immunity: the bodys ability to resist and fight disease reproduction: making more of the same organism enzymes: proteins responsible for building or breaking down organic molecules and work based on fitting into their substrate molecule (if it doesnt fit it doesnt work!) hormones: chemicals that respond through feedback loops to send messages throughout the body, they work based on fitting into receptor molecules on cells (if it doesnt fit it doesnt work!) Comparison Chart: FunctionSingle CellMulticellular organismGas exchangeCell membraneRespiratory systemTransport of substancesCytoplasmCirculatory systemNutritionVacuoles, chloroplastsDigestive systemRespirationMitochondriaCirculatory and respiratory system working togetherReproductionNucleusReproductive systemImmunityLysosomes Immune SystemMovement/locomotionCilia or flagellaSkeletomuscular system Immunity Specific Vocabulary: Pathogen: an organism (virus, fungus, bacteria) that causes disease Antigen: chemical produced by a pathogen Antibody: chemical made by white blood cells that recognizes antigens and marks pathogens to be killed by white blood cells White blood cells: cells that fight off disease by making antibodies or destroying pathogens Resistant: ability to fight off or survive Transplant: replacing a malfunctioning organ with one from another organism Immunosuppressant drugs: medicines that keep the immune system from responding and not accepting a donated organ Vaccine: a weakened or dead pathogen injected into the body to force antibody production so that someone wont get sick in the future Antibiotic: medicine used to fight off harmful bacteria Immune Response: When the body is infected with a pathogen, there is an incubation period: that means that the pathogen needs time to reproduce in our body and overcome our immune system before we will start to show signs and symptoms of being sick. During that period, our body is working hard to fight off the pathogen using the following methods:    Organ transplants work much like a pathogen: the new organ makes different chemicals that our organs so the body tries to fight off and kill the new organ the same way it would a pathogen (triggers an immune response). Doctors will use immunosuppressant drugs that shut down the immune system until the body recognizes that the new organ is not trying to hurt them. This is why stem cell research is being pushed: they could use it to clone organs from the individual and replace the non-working one that is the exact same! Allergies are related to both of these. Everything that we eat or come in contact with makes their own chemicals (proteins). Where most people may not have issues with things like peanuts, pollen, and animal dander, some peoples bodies see the proteins made by these things as dangerous and will react to them just like they were pathogens. Instead of the chemicals being called antigens, we call them allergens. It is easy to see the difference between a sickness caused by an allergen or by a pathogen because if you remove the source of the allergen, the person will get better in a short amount of time. Vaccines work based on the immune response. A vaccine is a weakened or dead form of the pathogen. When we get a vaccine (shot or immunization), the doctor is giving you a disease. This forces your body to make the antibodies to fight it off and kill it. Antibodies stay in your blood stream forever, so if you are ever exposed to the disease again, it will fight it off before you even know that you have it! Antibiotic resistance is based on evolution. Pathogens are living things too, so they want to survive just like we do. When we take antibiotics for a bacterial infection, they will kill off bacteria, but some bacteria have evolved to be harder to kill. If the antibiotic is not strong enough OR the bacteria has mutated so that the antibiotic doesnt fit with the receptor site anymore, the bacteria will continue to reproduce and make you sick. You will need a stronger antibiotic or wait until your immune system makes the antibodies and white blood cells before you get better. Sometimes you will feel better after taking an antibiotic for 3 of the 10 days that the doctor told you to take it. It is important to take it for the full 10 days to make sure both the least resistant and the extremely resistant bacteria are killed off or else you will get sick again AND it will be caused by the bacteria that is the hardest to kill. Pesticide resistant or Insecticide resistant insects (bugs) respond the same way as antibiotic resistant bacteria. Any questions based on this can be answered the same way you would answer for the bacteria! Hints: When studying, do NOT focus on each of the body systems.. simply know what each system does. DO focus on hormones, enzymes, immunity, and the reproductive system as this will be the majority of the questions from this unit. Practice Questions, Human Body Systems 1. Which sequence represents the correct order of events for the production of necessary complex molecules after food is taken in by a multicellular animal? (1) diffusion --> synthesis --> absorption --> digestion -->circulation (2) circulation --> diffusion --> synthesis --> absorption --> digestion (3) digestion --> absorption -->circulation --> diffusion --> synthesis (4) synthesis -->digestion --> absorption --> diffusion --> circulation 2. The interaction of which two systems provides the molecules needed for the metabolic activity that takes place at ribosomes? (1) digestive and circulatory (2) reproductive and excretory (3) immune and nervous (4) respiratory and muscular 3. Which system is correctly paired with its function? (1) immune systemintake and distribution of oxygen to cells of the body (2) excretory systemremove potentially dangerous materials from the body (3) digestive systemtransport energy-rich molecules to cells (4) circulatory systemproduce building blocks of complex compounds 4. When a new viral infection appears in a population, scientists usually try to develop a vaccine against the virus. Which substances would most likely be contained in the new vaccine? (1) live bacteria that ingest viruses (2) white blood cells from an infected individual (3) weakened viruses associated with the infection (4) a variety of microbes that will attack the virus An investigation is carried out to determine the effect of exercise on the rate at which a person can squeeze a clothespin. 5. In this investigation, the independent variable is the (1) control (2) exercise (3) rate of squeezing (4) number of participants 6. Muscle fatigue occurs during this activity when (1) carbon dioxide is used up in the muscle cells (2) simple sugar is converted to starch in the muscle cells (3) proteins accumulate in mitochondria in the muscle cells (4) certain waste products collect in the muscle cells 7. Which situation indicates a serious organ system malfunction? (1) The ovary releases estrogen, which quickly binds to cell receptors. (2) Blood flow throughout the entire body is suddenly reduced. (3) White blood cells release enzymes in response to the proteins on inhaled pollen. (4) Mitochondria stop functioning in a unicellular organism exposed to pollutants. 8. Drugs to reduce the risk of rejection are given to organ transplant patients because the donated organ contains (1) foreign antigens (2) foreign antibodies (3) DNA molecules (4) pathogenic microbes 9. Which body system is correctly paired with its function? (1) excretoryproduces antibodies to fight disease-causing organisms (2) digestiveproduces hormones for storage and insulation (3) circulatorytransports materials for energy release in body cells (4) respiratorycollects waste material for digestion 10. The failure to regulate the pH of the blood can affect the activity of (1) enzymes that clot blood (2) red blood cells that make antibodies (3) chlorophyll that carries oxygen in the blood (4) DNA that controls starch digestion in the blood 11. To replace burned skin, doctors can successfully transplant replacement skin taken from another part of the body of the burn victim. Which statement best explains why the transplanted skin is not rejected? (1) The transplanted skin is damaged, making the immune system nonfunctional. (2) The antigens of the replacement skin are the same as those of the damaged skin. (3) Burn victims lose so much blood that white blood cells cannot cause an immune response. (4) There is no blood supply to the skin, so mixing of antigens does not occur. 12. The ability of the human body to keep blood sugar levels within a fairly narrow range, despite the intake of meals high in carbohydrates, is an example of (1) active transport (2) genetic recombination (3) homeostasis (4) digestion 13. A vaccine used against an infectious disease may contain (1) specialized blood cells (2) toxic enzymes (3) a variety of antibiotics (4) weakened pathogens 14. Which activity would stimulate the human immune system to provide protection against an invasion by a microbe? (1) receiving antibiotic injections after surgery (2) choosing a well-balanced diet and following it throughout life (3) being vaccinated against chicken pox (4) receiving hormones contained in mothers milk while nursing 15. Certain microbes, foreign tissues, and some cancerous cells can cause immune responses in the human body because all three contain (1) antigens (3) fats (2) enzymes (4) cytoplasm 16. Some diseases and their causes are listed below. A. Fluinfluenza virus B. Lung cancersmoking C. Cystic fibrosisgenes D. Dysenteryparasitic ameba Which disease would individuals have the greatest difficulty preventing in themselves? (1) A (3) C (2) B (4) D 17. The diagram below shows a cell in the human body engulfing a bacterial cell.  The cell labeled X is most likely a (1) red blood cell (3) liver cell (2) white blood cell (4) nerve cell 18. Viruses frequently infect bacteria and insert new genes into the genetic material of the bacteria. When these infected bacteria reproduce asexually, which genes would most likely be passed on? (1) only the new genes (2) only the original genes (3) both the original and the new genes (4) neither the original nor the new genes 19. Which statement best describes how a vaccination can help protect the body against disease? (1) Vaccines directly kill the pathogen that causes the disease. (2) Vaccines act as a medicine that cures the disease. (3) Vaccines cause the production of specific molecules that will react with and destroy certain microbes. (4) Vaccines contain white blood cells that engulf harmful germs and prevent them from spreading throughout the body. Stem cells present in an embryo are responsible for the formation of various tissues and organs. Recent research suggests that it may be possible to replicate stem cells from sections of skin taken from adult mice, rather than having to use stem cells from the embryos of mice. In the future, human stem cells may be used to replace human tissue damaged by diseases such as Parkinsons disease and multiple sclerosis. 20. Discuss why the use of stem cells taken from a patient to replace damaged tissues and organs may decrease the potential risk to a patient. In your answer, be sure to: identify the major problem that may occur when tissues and organs donated by another individual are used [1] explain why this problem may occur [1] explain why this problem will not occur if tissues and organs produced by stem cells from the patient are used [1] ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ 21. The table below lists enzymes that function in different locations in the human body, and the temperature and pH ranges of these locations.  Different enzymes are secreted in each of the three locations. Ptyalin digests carbohydrates. Pepsin and trypsin both digest proteins. Discuss the activity of these enzymes. In your answer, be sure to: state how the activity of pepsin will most likely change after it moves with the food from the stomach to the small intestine [1] support your answer using data from the table [1] state how a fever of 40C would most likely affect the activity of these enzymes and support your answer [1] identify the characteristic of enzymes that prevents ptyalin and trypsin from digesting the same type of food [1] ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ A normally healthy 35-year-old woman was found to have a severe intestinal infection usually seen in much older and sicker patients in hospitals. Because of so many cases like hers, some doctors became alarmed that the organism responsible could spread rapidly and cause unusually severe illnesses and some deaths. Scientists suspect that the cause is a mutated form of an organism that has a resistance to some of the most common treatments. 22. Since it is difficult to cure an infection caused by this organism, it might be easier to prevent these infections by using a vaccine. Identify the specific material a vaccine would have to contain to prevent future infections. [1] ______________________________________________________________________ 23. Explain how this vaccine would prevent future infections. [1] ______________________________________________________________________ ______________________________________________________________________ 24. The mutated form of this type of organism could result from a change in a molecule within one member of the original population. Identify the molecule. [1] _____________________________________ 25. Staphylococcus aureus is a type of bacterium that lives on the skin and in the nostrils of most people. Generally, it is controlled by the immune system of the body. Occasionally, the antibiotic penicillin is needed to control the bacterium. However, some strains of S. aureus have a resistance to penicillin, which makes them hard to kill and infections difficult to cure. Explain how the resistance to penicillin affects the S. aureus population. In your answer, be sure to include an explanation of: how the exposure to penicillin affects the survival of some bacteria in the population [1] why the frequency of penicillin-resistant bacteria can change over time within the population [1] how it is still possible to cure patients who are infected with penicillin-resistant bacteria [1] ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ To most people, using maggots (fly larvae) for a medical treatment is not a great idea. However, to many doctors, fly larvae do have a place in medicine, and that place is inside open wounds. In maggot debridement therapy, live fly larvae are mixed into a dressing for a wound and the area is covered with gauze. Maggots, which will only eat dead tissue, feed on damaged flesh and leave the healthy tissue behind. In the process, the maggots excrete an antimicrobial chemical that helps cleanse the wound of pathogens. When the dressing is cut away two or three days later, the maggots, now up to 10 times their original size, are easily removed. People with diabetes often have impaired wound healing. This could lead to infection. Maggot therapy has been used to clean these types of wounds. 26. What is the meaning of the term debridement? (1) excretions of pathogens (2) impaired wound healing (3) removal of dead tissue (4) destruction of antimicrobial chemicals 27. Which group of terms best describes a maggot? (1) decomposer, prey, host (2) scavenger, heterotroph, consumer (3) producer, predator, parasite (4) pathogen, carnivore, autotroph 28. State one possible reason why slow healing of wounds can lead to infection. [1] ______________________________________________________________________ ______________________________________________________________________ 29. Two life functions performed by all living organisms are nutrition and respiration. Identify two other life functions that are essential for the survival of all living organisms. Explain how each of the two life functions you identified maintains homeostasis. [2] Life Function: _________________________________________ Explanation: ____________________________________________________________ ______________________________________________________________________ Life Function: _________________________________________ Explanation: ____________________________________________________________ ______________________________________________________________________ Many people have a sensitivity to peanuts. The symptoms can include watery, itchy eyes and difficulty breathing. This allergic reaction can be mild, severe, or fatal. 30. Discuss why an individual can have a sensitivity to peanuts. In your answer, be sure to: identify the human system that is responsible for this sensitivity to peanuts [1] identify the specific type of molecule that triggers an allergic reaction [1] state one reason why a person could be allergic to peanuts, but not be allergic to walnuts [1] describe how this reaction is similar to the rejection of a transplanted organ [1] ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ____________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________________ Proteins on the surface of a human cell and on a bird influenza virus are represented in the diagram below.  31. In the space below, draw a change in the bird influenza virus that would allow it to infect this human cell. [1] 32. Explain how this change in the virus could come about. [1] ______________________________________________________________________ ______________________________________________________________________ 33. Identify the relationship that exists between a virus and a human when the virus infects the human. [1] ______________________________________________________________________ ______________________________________________________________________ In Search of a Low-Allergy Peanut Many people are allergic to substances in the environment. Of the many foods that contain allergens (allergy-inducing substances), peanuts cause some of the most severe reactions. Mildly allergic people may only get hives. Highly allergic people can go into a form of shock. Some people die each year from reactions to peanuts. A group of scientists is attempting to produce peanuts that lack the allergy-inducing proteins by using traditional selective breeding methods. They are searching for varieties of peanuts that are free of the allergens. By crossing those varieties with popular commercial types, they hope to produce peanuts that will be less likely to cause allergic reactions and still taste good. So far, they have found one variety that has 80 percent less of one of three complex proteins linked to allergic reactions. Removing all three of these allergens may be impossible, but even removing one could help. Other researchers are attempting to alter the genes that code for the three major allergens in peanuts. All of this research is seen as a possible long-term solution to peanut allergies. 34. Allergic reactions usually occur when the immune system produces (1) antibiotics against usually harmless antigens (2) antigens against usually harmless antibodies (3) antibodies against usually harmless antigens (4) enzymes against usually harmless antibodies 35. How does altering the DNA of a peanut affect the proteins in peanuts that cause allergic reactions? (1) The altered DNA is used to synthesize changed forms of these proteins. (2) The altered DNA leaves the nucleus and becomes part of the allergy-producing protein. (3) The altered DNA is the code for the antibodies against the allergens. (4) The altered DNA is used as an enzyme to break down the allergens in peanuts. 36. Explain how selective breeding is being used to try to produce commercial peanuts that will not cause allergic reactions in people. [1] ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ Until the middle of the 20th century, transplanting complex organs, such as kidneys, was rarely successful. The first transplant recipients did not survive. It was not until 1954 that the first successful kidney transplant was performed. Success with transplants increased as research scientists developed techniques such as tissue typing and the use of immunosuppressant drugs. These are drugs that suppress the immune system to prevent the rejection of a transplanted organ. In 2002, there were nearly 15,000 kidney transplants performed in the United States with a greater than 95% success rate. 37. Describe the relationship of the immune system to organ transplants and the use of immunosuppressant drugs to prevent the rejection of a transplanted organ. In your answer be sure to: state one way the immune system is involved in the rejection of transplanted organs [1] explain why the best source for a donated kidney would be the identical twin of the recipient [1] explain why immunosuppressant drugs might be needed to prevent rejection of a kidney received from a donor other than an identical twin [1] state one reason a person may get sick more easily when taking an immunosuppressant drug [1] ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ Growers of fruit trees have always had problems with insects. Insects can cause visible damage to fruits, making them less appealing to consumers. As a result of this damage, much of the fruit cannot be sold. Insecticides have been useful for controlling these insects, but, in recent years, some insecticides have been much less effective. In some cases, insecticides do nothing to stop the insect attacks. 38. Provide a biological explanation for this loss of effectiveness of the insecticides. In your answer, be sure to: identify the original event that resulted in the evolution of insecticide resistance in some insects [1] explain why the percentage of resistant insects in the population has increased [1] describe one alternative form of insect control, other than using a different insecticide, that fruit growers could use to protect their crops from insect attack [1] ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ____________________________________________________________________________________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ ______________________________________________________________________ Base your answers to questions 39 through 41 on the information below and on your knowledge of biology. Vaccines play an important role in the ability of the body to resist certain diseases. 39. Describe the contents of a vaccine. [1] ______________________________________________________________________ ______________________________________________________________________ 40. Identify the system in the body that is most directly affected by a vaccination. [1] ________________________________________ 41. Explain how a vaccination results in the long-term ability of the body to resist disease. 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T cells will then make antibodies that mark the pathogen that needs to be taken care of. A pathogen is a living thing and makes its own chemicals for life. 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