ࡱ> ')&'` 0Tbjbj{P{P ;::,$$8@ L $ ddddd???  $F h  9????? ddJ  ?dd ?  dX ИfcEX ` 0 p  T ???  v??? ????$$$$$$$$$ COMPLICATIONS OF LOW-DOSE, ECHO-GUIDED ALCOHOL SEPTAL ABLATIONS FOR OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY J. Veselka, D. Zemanek, P. Tomasov, S. Homolova, R. Adlova CardioVascular Center, University Hospital Motol, Prague, Czech Republic Background: Alcohol septal ablation (ASA) is a catheter-based intervention that has been used as an alternative to surgical myectomy in highly symptomatic patients with hypertrophic obstructive cardiomyopathy (HOCM). Methods: This retrospective study was designed to evaluate the incidence of major complications in the mid-term follow-up of low-dose (d"2.5 ml of ethanol), echo-guided alcohol septal ablation. Results: A total of 101 consecutive patients (5615 years) with highly symptomatic HOCM were enrolled. At 6 months, there was a significant decrease in resting outflow gradient accompanied by reduction in basal septal diameter and improvement in symptoms (p < 0.01). Two patients (2%) experienced procedural ventricular tachycardias terminated by electrical cardioversion. A total of 87 patients (86%) underwent an uneventful post-procedural hospital stay. The post-procedural complete heart block occurred in 10 patients (10%), and subsequent permanent pacemaker was implanted in 4 cases (4%). Sustained ventricular arrhythmias requiring electrical cardioversion occurred in 4 patients (4%) within post-procedural hospital stay. Subsequently, ICD was not implanted in any of these cases. The patients were repeatedly examined by Holter ECG monitoring, and in the mid-term follow-up (6-50 months) they stayed asymptomatic and without any ventricular arrhythmias. Conclusions: The present study demonstrates the same early incidence of complete heart block requiring permanent pacemaker implantation (4%) and sustained ventricular arrlmopwxz{|   | ~ t RS/0235689;QRSTɎhuLhjhUU ho9ho9 ho9h2O ho9h!h!B*phP8 h!B*phhcIh2Oh2Oh!56\]h2Oh2O5>*\hcI5>*\h!C5>*\h! h!5\0m  S./124578:;QRST $1$7$8$H$a$1$7$8$H$/Shythmias following low-dose, echo-guided ASA.     1042, either, cat. 34 90&P P:p2O. A!"#$% @@@ NormalCJ_H aJmH sH tH DAD Default Paragraph FontRiR  Table Normal4 l4a (k(No List 4@4 2OHeader  !4 @4 2OFooter  !QmS+,/258NR0000000000000@0 #####&TT S 8@0(  B S  ?| nv|ag&+,,..//124578OR,,..//124578OR+,,-..//0124578MORSW+,,..//124578OR 6, J-W;g^=!C/{DcIuLw^9'o9!-2O+R@^ 4QP@P P@P0@UnknownG:Ax Times New Roman5Symbol3& :Cx Arial"hybfybfq3f  !xx))2?!2lCOMPLICATIONS OF LOW-DOSE, ECHO-GUIDED ALCOHOL SEPTAL ABLATIONS FOR OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY RamiadminOh+'0$4@L` p|    pCOMPLICATIONS OF LOW-DOSE, ECHO-GUIDED ALCOHOL SEPTAL ABLATIONS FOR OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY Rami Normal.dotadmin2Microsoft Office Word@@6ڽ@FQ@FQ՜.+,0\ hp  = Atartica )' mCOMPLICATIONS OF LOW-DOSE, ECHO-GUIDED ALCOHOL SEPTAL ABLATIONS FOR OBSTRUCTIVE HYPERTROPHIC CARDIOMYOPATHY Title  !"#$%(Root Entry Fmc*1TableWordDocument;SummaryInformation(DocumentSummaryInformation8CompObjq  FMicrosoft Office Word Document MSWordDocWord.Document.89q