ࡱ> BDAy bjbjEE 74'' ||$\SSSSS...CEEEEEE$^|i.....iSS~.SSC.CSX./0.f\.......ii................| : CHAPTER 20,21 LYMPHATIC and IMMUNE functions circulation maintain blood volume absorb excess fluid from tissues return fluid to subclavian vein defense destroy pathogens produce lymphocytes produce antibodies Lymphatic structures circulation lymph capillaries lymphatic vessels lymph ducts lymphoid tissues defense lymph nodes tonsils MALT spleen thymus general plan excess tissue fluid forms from blood capillaries tissue fluid absorbed into lymph capillaries = lymph capillaries form lymph vessels pass through lymph nodes for immune function join to form lymph ducts return lymph to subclavian veins lymph capillaries function : absorb excess fluid from interstitial spaces very permeable endothelium one way flaps fluid only flows in also absorbs bacteria, virus, other cells lacteals - lymph capillaries in small intestine absorb lipids lymph vessels lymphatic collecting vessels collect from lymph capillaries 2 or 3 tunics lymph trunks formed from vessels lymph ducts 2 large ducts return lymph to blood lymph ducts function : return fluid to subclavian veins main vessels : thoracic duct collects all except right upper quadrant cisterna chyli collects lower extremities and intestines returns to left subclavian veins right lymphatic duct collects from right upper quadrant returns to right subclavian vein lymph nodes collection of lymphoid cells function : destroy pathogens filter lymph before return to blood afferent lymphatic vessels enters node efferent lymphatic vessels leaves node follicles lymphoid tissue lymphocytes macrophages lymph plexus group of lymph nodes at attachments of head and extremities : cervical plexus axillary plexus (+ mammary plexus) inguinal plexus most infections occur in extremities plexus protects against invasion of torso and blood lymphoid tissue large collection of lymphocytes MALT = mucosa associated lymphoid tissue at mucus membranes and orifices tonsils Palatine tonsils lateral wall of pharynx Pharyngeal tonsil = Adenoid behind nose Lingual tonsil base of tongue tubal tonsils pharyngotympanic tube Peyers patches line small intestine Spleen largest lymph organ filters blood (not lymph vessels) 2 functions: destroy pathogens in blood: white pulp lymphoid tissue lymphocytes and macrophages destroy old RBC: red pulp macrophages splenic a and v. central artery branches to pulp areas Thymus 2 lobes posterior to sternum site of maturation of T lymphocytes immunocompetence self-tolerance most active to age 20 does not fight pathogens ! defense systems nonspecific defenses same against all pathogens barriers skin , mucosa phagocytes specific defenses attacks specific pathogen adaptive defenses memory 2nd response stronger than 1st = immunity defense cells phagocytes neutrophils tissue macrophages lymph nodes spleen connective tissues fixed macrophages liver (kupffer cells) microglia lung (alveolar macrophages) lymphocytes blood and lymph nodes types of cells T lymphocytes cellular immunity helper T cells recognize foreign antigen stimulate T and B cells cytotoxic T cells destroy foreign cells memory T cells 2nd response much stronger B lymphocytes humoral immunity plasma cells produce antibodies memory cells 2nd response much stronger immunodeficiency failure of immune response HIV = human immunodeficiency virus attacks T cells AIDS = acquired immune deficiency syndrome HIV positive plus symptoms Hodgkins lymph node cancers   $%&0;R   & ' @ T U Y Z h i v  e f x N V d f t    K ļĴۨĕxhD >*CJaJhp0h?CJaJh?>*CJaJhp0hp0CJaJh$ kCJaJhp0hp0>*CJaJhp0CJaJh3xCJaJhp0h3xCJaJhp0h3x>*CJaJh3x>*CJaJ h|5>* hp05>* h)5>* h5>*/%&0St & F7$8$@&H$^`gdp0 $7$8$@&H$a$gdp0 & FL7$8$@&H$^`LgdD  & FL7$8$@&H$^`Lgd3x & F7$8$@&H$^`gd3x $7$8$@&H$a$gd3x$a$gdp0   ' A M U Z a h i v + D e  & F7$8$@&H$^`gdD $7$8$@&H$a$gdp0 & F7$8$@&H$^`gdp0 & FL7$8$@&H$^`Lgdp0 & F7$8$@&H$^`gd3xe f x   d e f t 7$8$@&H$gdD 7$8$@&H$^`gdp0I7$8$@&H$^I`gdp0 & FI7$8$@&H$^I`gdp0 & F7$8$@&H$^`gdp0 $7$8$@&H$a$gdp0    I X h  & FL7$8$@&H$^`Lgdp0 & FI7$8$@&H$^I`gdp0 $7$8$@&H$a$gdp0 & FI7$8$@&H$^I`gdR & F7$8$@&H$^`gdp0 & FI7$8$@&H$^I`gd?  ) J K W t pp & F7$8$@&H$^`gdD  & F7$8$@&H$^`gdp0 $7$8$@&H$a$gdp07$8$@&H$^`gdp0 & FI7$8$@&H$^I`gdp0 & FL7$8$@&H$^`Lgdp0 & FTL7$8$@&H$^T`Lgdp0 K W t  +,CDERf-.>&6G!"123?JK-.9^ğ󗌗،hp0h(CJaJh(CJaJh(>*CJaJhD CJaJhD hD CJaJhD >*CJaJh?>*CJaJhp0h3xCJaJhp0CJaJh3xCJaJhp0hp0CJaJhp0hp0>*CJaJ7,8DERg-.>^ & FI7$8$@&H$^I`gdp0 & F7$8$@&H$^`gdp0 $7$8$@&H$a$gdp0 & F7$8$@&H$^`gd3x & F7$8$@&H$^`gd?6]m"37$8$@&H$^`gdp0 $7$8$@&H$a$gdp0 & FI7$8$@&H$^I`gdD  & FI7$8$@&H$^I`gdp0 & F7$8$@&H$^`gdp03?K\. & F7$8$@&H$^`gdp0 $7$8$@&H$a$gdp07$8$@&H$^`gdp0 & F7$8$@&H$^`gd3x & FI7$8$@&H$^I`gdp0 & F7$8$@&H$^`gdD .^v mp & F7$8$@&H$^`gdp0 $7$8$@&H$a$gdp07$8$@&H$^`gdp0 & FI7$8$@&H$^I`gdp0 & FI7$8$@&H$^I`gdD  & FI7$8$@&H$^I`gd( & F7$8$@&H$^`gd(   '+8W^ 345EFeg貧躒节hCJaJhWCJaJhW>*CJaJhp0h(CJH*aJhp0h(CJaJh?CJaJh?>*CJaJh(CJaJhp0hp0>*CJaJh(>*CJaJhp0CJaJhp0hp0CJaJhp0hp0CJH*aJ2(v 45Fa 7$8$@&H$gdD 7$8$@&H$^`gdp0 & FI7$8$@&H$^I`gdp0 & F7$8$@&H$^`gdp0 $7$8$@&H$a$gdp0 & F7$8$@&H$^`gd(a & F7$8$@&H$^`gdWhp0hWCJaJ501F:pQ / =!"#$% ^ 2 0@P`p2( 0@P`p 0@P`p 0@P`p 0@P`p 0@P`p 0@P`p8XV~_HmH nH sH tH @`@ NormalCJ_HaJmH sH tH DA D Default Paragraph FontRiR  Table Normal4 l4a (k (No List PK![Content_Types].xmlj0Eжr(΢Iw},-j4 wP-t#bΙ{UTU^hd}㨫)*1P' ^W0)T9<l#$yi};~@(Hu* Dנz/0ǰ $ X3aZ,D0j~3߶b~i>3\`?/[G\!-Rk.sԻ..a濭?PK!֧6 _rels/.relsj0 }Q%v/C/}(h"O = C?hv=Ʌ%[xp{۵_Pѣ<1H0ORBdJE4b$q_6LR7`0̞O,En7Lib/SeеPK!kytheme/theme/themeManager.xml M @}w7c(EbˮCAǠҟ7՛K Y, e.|,H,lxɴIsQ}#Ր ֵ+!,^$j=GW)E+& 8PK!Ptheme/theme/theme1.xmlYOo6w toc'vuر-MniP@I}úama[إ4:lЯGRX^6؊>$ !)O^rC$y@/yH*񄴽)޵߻UDb`}"qۋJחX^)I`nEp)liV[]1M<OP6r=zgbIguSebORD۫qu gZo~ٺlAplxpT0+[}`jzAV2Fi@qv֬5\|ʜ̭NleXdsjcs7f W+Ն7`g ȘJj|h(KD- dXiJ؇(x$( :;˹! I_TS 1?E??ZBΪmU/?~xY'y5g&΋/ɋ>GMGeD3Vq%'#q$8K)fw9:ĵ x}rxwr:\TZaG*y8IjbRc|XŻǿI u3KGnD1NIBs RuK>V.EL+M2#'fi ~V vl{u8zH *:(W☕ ~JTe\O*tHGHY}KNP*ݾ˦TѼ9/#A7qZ$*c?qUnwN%Oi4 =3ڗP 1Pm \\9Mؓ2aD];Yt\[x]}Wr|]g- eW )6-rCSj id DЇAΜIqbJ#x꺃 6k#ASh&ʌt(Q%p%m&]caSl=X\P1Mh9MVdDAaVB[݈fJíP|8 քAV^f Hn- "d>znNJ ة>b&2vKyϼD:,AGm\nziÙ.uχYC6OMf3or$5NHT[XF64T,ќM0E)`#5XY`פ;%1U٥m;R>QD DcpU'&LE/pm%]8firS4d 7y\`JnίI R3U~7+׸#m qBiDi*L69mY&iHE=(K&N!V.KeLDĕ{D vEꦚdeNƟe(MN9ߜR6&3(a/DUz<{ˊYȳV)9Z[4^n5!J?Q3eBoCM m<.vpIYfZY_p[=al-Y}Nc͙ŋ4vfavl'SA8|*u{-ߟ0%M07%<ҍPK! ѐ'theme/theme/_rels/themeManager.xml.relsM 0wooӺ&݈Э5 6?$Q ,.aic21h:qm@RN;d`o7gK(M&$R(.1r'JЊT8V"AȻHu}|$b{P8g/]QAsم(#L[PK-![Content_Types].xmlPK-!֧6 +_rels/.relsPK-!kytheme/theme/themeManager.xmlPK-!Ptheme/theme/theme1.xmlPK-! ѐ' theme/theme/_rels/themeManager.xml.relsPK] 4K  e 3.a 8@0(  B S  ? &AUZiv+DfxfIhtDEg.\ . v   ( 5 a .*`Lb @CJOJQJ^Jo(" c @CJOJQJ^Jo( (c`i@CJOJQJ^Jo(R((I+p0[3?$ k3x?Q D WMG)| @ 0^  X@UnknownG*Ax Times New Roman5Symbol3. *Cx ArialA BCambria Math"1h祿ff  x4 2QHP ?p02!xx!CHAPTER 16 LYMPHATIC and IMMUNEGaryGary Oh+'0`    ( 4@HPX$CHAPTER 16 LYMPHATIC and IMMUNEGaryNormalGary6Microsoft Office Word@_@&X@$C@&X ՜.+,0 hp|    "CHAPTER 16 LYMPHATIC and IMMUNE Title  !"$%&'()*+,-./02345678:;<=>?@CRoot Entry FXEData 1Table#WordDocument74SummaryInformation(1DocumentSummaryInformation89CompObjy  F'Microsoft Office Word 97-2003 Document MSWordDocWord.Document.89q