ࡱ> egbcd fwbjbjcTcT *>>fottKfklAKCKCKCKCKCKCK$(NPRgK|#|#|#gK|K,,,|#AK,|#AK,,DFԡ~N(cE-KK0K}EQN(Q4FF*Q-HV, gKgK, K|#|#|#|#Qt }: Didactic: Common Pediatric Rashes Author: Steve Caddle, MD Learning Objectives: Identify common pediatric rashes and their causes Outline indications for treatment and therapeutics for common pediatric rashes References are listed at the end of the didactic. A 10-year-old girl with atopic dermatitis reports itching that has recently become relentless, resulting in sleep loss. Her mother has been reluctant to treat the girl with topical corticosteroids, because she was told that they damage the skin, but she is exhausted and wants relief for her child. 1. What is atopic dermatitis?2. What causes it?3. What questions would you ask the parent?4. How should the problem be managed? A 3-month-old girl developed an asymptomatic scaly red eruption in the diaper area and the face. The lesions in the diaper area were well circumscribed and red-orange in color. 1. What is the rash?2. What causes it?3. How do you manage it? A 6-month-old boy presents with a diaper rash consisting of confluent, bright red papules and plaques with scattered pustules, overlying scale, and satellite lesions at the periphery. 1. What is the rash?2. What causes it?3. How do you manage it? A mother describes to you a diaper rash that cleared rapidly with frequent application of a barrier paste and air drying after diaper changes. She wants to know why this happens. 1. What is the cause of this rash?2. How do you manage it? A 2-month-old healthy boy developed a pustular eruption in the diaper area 2 days ago. A Gram stain showed neutrophils and Gram positive cocci. 1. What is the rash?2. What causes it?3. How do you treat it? A 10-year-old boy developed asymptomatic relapsing and remitting hypopigmented minimally scaly patches on his facial cheeks. 1. What is the rash?2. What causes it?3. How do you manage it? A healthy adolescent developed a large scaly red patch on the back followed a week later by a widespread papulosquamous eruption. The lesions were primarily truncal and only minimally pruritic. 1. What is the rash?2. What causes it?3. How do you mange it and what is the expected outcome? An 18-year-old boy was evaluated for facial acne. He had multiple open and closed comedone and a few red papules and pustules on his malar and temporal areas. 1. What causes acne vulgaris?2. What are the different types?3. How do you manage it? A 17-year-old boy complained of dry scaly sandpaper like papules on the extensor surfaces of his upper arms and thighs for as long as he could remember. His father had similar lesions. 1. What is the rash?2. What causes it?3. How do you manage it? An 8-year-old boy demonstrated an annular scaly plaque on the neck extending into the scalp with broken hairs and a prominent right occipital lymph node. 1. What is the rash?2. What causes it?3. How do you treat it? A 10-year-old boy developed an expanding annular plaque on the anterior neck. A potassium hydroxide preparation showed branching hyphae. 1. What is the rash?2. What causes it?3. How do you treat it? A 16-year-old soccer player complained of intense itching and burning in the groin for 1 week. He attributed the rash to playing matches in the rain for the preceding 2 weeks. 1. What is the rash?2. What causes it?3. How do you treat it? A 20-year-old man had extensive tinea pedis involving the soles, undersurfaces of the toes, and web spaces of both feet. 1. What is the rash?2. What causes it?3. How do you treat it? An 8-year-old girl was evaluated for multiple hypopigmented macules on her face. A potassium hydroxide preparation made from a scraping of fine scale from the macules showed pseudohyphae and spores. 1. What is the rash?2. What causes it?3. How do you treat it? An otherwise-healthy 6-year-old boy presents for evaluation of multiple papules on his arms, legs, and trunk. He has developed over 50 of these lesions, which are asymptomatic, over the last 4-5 months. 1. What is the most likely etiology?2. What causes it?3. How do you treat it? A 9-year-old healthy boy developed persistent warts on his hands that spread to his upper lip and hard palate. 1. What are the different types of warts?2. What is the etiology?3. What are his treatment options? A 19-year-old notes diffuse, intense itching. He reports that his girlfriend has the same itching. Examination of the skin reveals interdigital lesions, with small papules, vesicles, and excoriations on the hands, and indurated nodules on the genitalia. 1. What is the rash?2. What causes it?3. How do you treat it and what is the expected outcome? A 7-year-old girl is sent home after the school nurse detects head lice. She will not be permitted to return to school until the absence of infestation is documented. What treatment strategy is most likely to allow her to return to school with a minimal risk of infecting her classmates? 1. What is the technical term for head lice?2. How does it develop?3. How do you treat it? ATOPIC DERMATITIS Knoell KA and Greer KE.  HYPERLINK "http://pedsinreview.aappublications.org/cgi/content/full/20/2/46" Atopic Dermatitis. Pediatr. Rev. 1999; 20:46-52. Williams H.C.  HYPERLINK "http://content.nejm.org/cgi/content/full/352/22/2314" Atopic Dermatitis. NEJM. 2005. 352:2314-2324. SEBORRHEIC DERMATITIS Schwartz RA, Janusz CA, and Janniger CK. Seborrheic Dermatitis: An Overview. Am Fam Physician 2006;74:125-30. (Accessed 11/27/07 at  HYPERLINK "http://www.aafp.org/afp/20060701/125.pdf" http://www.aafp.org/afp/20060701/125.pdf.) DIAPER DERMATITIS Gupta AK, and Skinner AR. Management of diaper dermatitis. Int J Derm. 2004; 43 (11), 830834. PITYRIASIS ROSEA Hartley, AH.  HYPERLINK "http://pedsinreview.aappublications.org/cgi/reprint/20/8/266?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext=pityriasis&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT" Pityriasis. Pediatr. Rev. 1999; 20: 266 270. ACNE Zaenglein A.L. et al.  HYPERLINK "http://pediatrics.aappublications.org/cgi/content/full/118/3/1188" Expert Committee Recommendations for Acne Management. Pediatrics September 2006. TINEA Shy R.  HYPERLINK "http://pedsinreview.aappublications.org/cgi/reprint/28/5/164?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=1&title=tinea+corporis&andorexacttitle=and&andorexacttitleabs=and&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT" Tinea Corporis and Tinea Capitis. Pediatr. Rev. 2007;28;164-174. MOLLUSCUM CONTAGIOSUM / WARTS Husar K, Skerlev M. Molluscum contagiosum from infancy to maturity. Clin Dermatol. 2002 Mar-Apr; 20( 2): 170-172. Stulberg DL, Hutchinson AG. Molluscum contagiosum and warts. Am Fam Physician. 2003; 67( 6): 1233-1240. (Accessed 11/27/07 at  HYPERLINK "http://www.aafp.org/afp/20030315/1233.pdf" http://www.aafp.org/afp/20030315/1233.pdf.) Silverberg NB: Human papillomavirus infections in children. Curr Opin Pediatr 2004 Aug; 16(4): 402-9. SCABIES Stricker T, Sennhauser FH.  HYPERLINK "http://pedsinreview.aappublications.org/cgi/reprint/21/12/428?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext=scabies&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT" Visual Diagnosis: A Family That Has an Itchy Rash. Pediatr. Rev. 2000; 21: 428 431. LICE Head lice infestation. Atlanta: Centers for Disease Control and Prevention, 2001. (Accessed October 24, 2007, at  HYPERLINK "http://www.cdc.gov/ncidod/dpd/parasites/lice/default.htm" http://www.cdc.gov/ncidod/dpd/parasites/lice/default.htm.) Roberts RJ. HYPERLINK "http://content.nejm.org/cgi/reprint/346/21/1645.pdf"Head Lice. NEJM 2002, 346: 1645-1650. Didactic: Common Pediatric Rashes Author: Steve Caddle Learning Objectives: Identify common pediatric rashes and their causes Outline indications for and treatment(s) of common pediatric rashes References are listed at the end of the didactic. A 10-year-old girl with atopic dermatitis reports itching that has recently become relentless, resulting in sleep loss. Her mother has been reluctant to treat the girl with topical corticosteroids, because she was told that they damage the skin, but she is exhausted and wants relief for her child.1. What is atopic dermatitis?A chronic, relapsing skin disorder characterized by dryness of the skin and pruritus. Generalized with diaper-area sparing in infants, flexural in older children.2. What causes it?Thought to be related to overactivity of Th2 lymphocytes but likely a combination of genetic and environmental factors: (1) genetic predisposition (2) triggers: irritants, heat & humidity, allergens (dust mites, pollens, molds), infections (Staph aureus colonization acts as a superantigen) (3) food sensitivity (10% of children): cows milk protein, soy, wheat, eggs, peanuts 3. What questions would you ask the parent?Lotions, soaps, detergents used? Fabrics? Frequency of bathing? Association with any foods? Previous treatments? Family history?3. How should the problem be managed?PREVENTION and TREATMENT of FLARES: (1) parent education and allergen avoidance, (2) dry skin care: brief & limited bath/shower, mild soap/cleanser, pat dry (not rub) skin, emollients/moisturize immediately after bath & several times daily, (3) topical corticosteroids: ointments better than creams, 1-2x daily; steroid 1st, then emollient; mid- to high-potency x 3-7 days, then low-potency 1-2 weeks for flares, low-potency only to face, (4) antihistamines reserved for bedtime or severe cases, hydroxyzine 1-2 mg/kg/day Q6, (5) complications: eczema herpeticum (needs acyclovir), erythroderma (may need IV fluids), impetigo/superinfection (antibiotics), (6) topical calcineurin inhibitors: +black-box warning + rare skin malignancies/lymphoma but no causal relationship established; avoid long-term use; not under 2 years; use only in areas of mild-mod (pimecrolimus/Elidel 1% cr) or mod-severe (tacrolimus/Protopic 0.03% oint for ages 2-15) AD when alternatives are inadvisable or pt unresponsive to other Tx. STEROIDS} Class 1 = highest potency (ie. clobetasol), Class 7 = lowest potency (ie. hydrocortisone)A 3-month-old girl developed an asymptomatic scaly red eruption in the diaper area and the face. The lesions in the diaper area were well circumscribed and red-orange in color.1. What is the rash?Seborrheic dermatitis, a usually non-pruritic skin disorder of infancy and adolescence, characterized by a red scaling eruption that occurs predominantly on hair-bearing and intertriginous areas [scalp, eyebrows, eyelashes, paranasal, postauricular areas, neck, axillae, and groin].2. What causes it?Unknown but Pityrosporum and Candida species have been associated agents3. How do you manage it?Varies from no treatment to mineral oil (cradle cap), seborrheic shampoos (Nizoral/ketoconazole or selenium sulfide 2.5% BIW) topical (mid/low potency) steroids and/or antifungals for skin involvement A 6-month-old boy presents with a diaper rash consisting of confluent, bright red papules and plaques with scattered pustules, overlying scale, and satellite lesions at the periphery.1. What is the rash?Candidal diaper dermatitis, a bright red eruption with sharp borders and pinpoint satellite papules and pustules, involving exposed skin as well as intertriginous areas.2. What causes it?Candida organisms in conjunction with epidermal maceration and loss of barrier function due to prolonged contact with urine and feces.3. How do you manage it?Topical antifungal (Nystatin cream after diaper changes or Clotrimazole 1% cr BID), may add hydrocortisone 1% cr. BID. Frequent diaper changing, air drying, and use of barrier ointments (ie. white petrolatum or zinc oxide) are important for prevention. A mother describes to you a diaper rash that cleared rapidly with frequent application of a barrier paste and air drying after diaper changes. She wants to know why this happens.1. What is the cause of this rash?Epidermal maceration and loss of barrier function due to fecal enzymes (lipase & protease) activated by alkalinity of urine, leading to an erythematous, scaly, often macerated eruption involving convex surfaces of the perineum, lower abdomen, buttocks, and proximal thighs, with sparing of the intertriginous areas.2. How do you manage it?Frequent diaper changes with gentle, thorough cleansing, and air drying; application of barrier ointment; may need short course of low-potency steroids.A 2-month-old healthy boy developed a pustular eruption in the diaper area 2 days ago. A Gram stain showed neutrophils and Gram positive cocci.1. What is the rash?Staphylococcal pustulosis, a primary or secondary infection, typically in the first few weeks of life, characterized by thin-walled pustules on an erythematous base which tend to rupture and produce a collarette of scaling around the denuded red base.2. What causes it?Staphylococci bacteria.3. How do you treat it?Oral and/or topical antibiotics.A 10-year-old boy developed asymptomatic relapsing and remitting hypopigmented minimally scaly patches on his facial cheeks.1. What is the rash?Pityriasis alba, a self-limited eruption of poorly demarcated, hypopigmented, fine scaly patches measuring 2 to 4 cm and noted most commonly in the face, neck shoulders. Initial lesions may involve erythema and itching.2. What causes it?Thought to be along the spectrum of atopic dermatitis.3. How do you manage it?Emollients; may use low potency steroids in the beginning, when pruritus is more likely.A healthy adolescent developed a large scaly red patch on the back followed a week later by a widespread papulosquamous eruption. The lesions were primarily truncal and only minimally pruritic.1. What is the rash?Pityriasis rosea, a benign self-limited eruption, starts with a herald patch (in 80%, 2-6cm round erythematous, scaly patch) followed 5-10 days later by 1-2cm oval scaly papules over trunk & upper arms, parallel to lines of cleavage (Christmas tree distribution). Often pruritic. Can last up to 12 weeks.2. What causes it?Unknown; thought to be viral, HHV-6 and HHV-7 have been considered3. How do you manage it and what is the expected outcome?For pruritus: calamine lotion, zinc oxide, and/or topical steroids; short-term UV-B for severe. Rash can persists for 8 to 12 weeks.An 18-year-old boy was evaluated for facial acne. He had multiple open and closed comedone and a few red papules and pustules on his malar and temporal areas.1. What causes acne vulgaris?Typically begins during puberty with increased androgen production leading to (1) increased sebum production and (2) abnormal keratinization of the follicular epithelium, in the setting of (3) bacterial proliferation (Propionibacterium) and (4) inflammation. These four factors within the pilosebaceous (follicle) unit produce non-inflammatory (comedones open[blackheads] and closed[whiteheads]) and inflammatory (papules, pustules, nodules) lesions.2. What are the different types?Commonly classified as comedonal, mild (comedones + papules), moderate (comedones + papules + pustules) or severe (previous three + nodules).3. How do you manage it?Benzoyl peroxide (comedolytic /antibacterial) 5% or 10% gel; topical retinoids (adapalene, tretinoin), topical antibiotics [(clindamycin, erythromycin) least desirable] or antibiotic/BP preparations [(Benzamycin, BenzaClin) most desirable], combination OCPs (increase sex hormone binding globulin and decreases free testosterone), systemic antibiotics (doxycycline) or retinoids (isotretinoin for severe acne teratogenic; must sign up with registry, females sign informed consent to be on OCPs and have monthly pregnancy tests per FDA 3/06). Little/no role for diet or incessant washing with astringents.A 17-year-old boy complained of dry scaly sandpaper like papules on the extensor surfaces of his upper arms and thighs for as long as he could remember. His father had similar lesions.1. What is the rash?Keratosis Pilaris: a common, benign hyperkeratotic disorder that manifest as 1-2mm folliculocentric papules. Affects 50-80% of adolescents, 40% of adults. Improves in summer. Goose pimple appearance of posterolateral upper arms, anterior thighs, facial cheeks.2. What causes it?Unknown. Some genetic predisposition.3. How do you manage it?Emollients; if prominent inflammatory eruptions, medium-potency steroid x 7 days; Combination 2-3% salicylic acid in 20% urea cream also effective for management.An 8-year-old boy demonstrated an annular scaly plaque on the neck extending into the scalp with broken hairs and a prominent right occipital lymph node.1. What is the rash?Tinea capitis: most common fungus infection in kids ages 2-10 yrs and typically presents with alopecia, scales, erythema with slightly raised borders and broken hairs on the scalp or hairline. Infrequently associated with kerions (boggy inflammatory scalp lesions) or id reactions / autoeczematization (pruritic morbilliform rash).2. What causes it?Fungi including Trichophyton tonsurans and Microsporum spp. Passed from fallen hairs, dandruff, shared combs, towels, and hats.3. How do you treat it?Griseofulvin 15-25 mg/kg for 6-8 weeks, ketoconazole, or Lamisil (sprinkles available); Nizoral or Selenium sulfide 2.5% shampoo BIW; may attend school during treatment; not necessary to shave head or wear a cap.A 10-year-old boy developed an expanding annular plaque on the anterior neck. A potassium hydroxide preparation showed branching hyphae.1. What is the rash?Superficial dermatophyte infection of the glabrous skin characterized by inflammatory and noninflammatory lesions2. What causes it?Fungi including Trichophyton, Microsporum, and Epidermophyton spp.; often acquired by children from animals3. How do you treat it?Topical antifungal to an area at least 2 cm beyond the edge of the lesion 1-2x daily for at least 2 weeks; systemic antifungal therapy for extensive or resistant lesions A 16-year-old soccer player complained of intense itching and burning in the groin for 1 week. He attributed the rash to playing matches in the rain for the preceding 2 weeks.1. What is the rash?Tinea cruris: a pruritic superficial fungal infection of the groin and adjacent skin; more common in adolescent males and adults; penis and scrotum are spared.2. What causes it?Fungi including Trichophyton and Epidermophyton spp.3. How do you treat it?Topical antifungal (azoles [ketoconazole] or allylamines [terbinafine/Lamisil or naftifine/Naftin]; dry the area after bathing; recurs frequentlyA 20-year-old man had an extensive itchy rash involving the soles, undersurfaces of the toes, and web spaces of both feet.1. What is the rash?Tinea pedis: most common dermatophyte infection worldwide; involving the feet (asymptomatic or pruritic erythema with scaling) and/or interdigital spaces (maceration, fissuring, and scaling)2. What causes it?Most commonly Trichophyton rubrum; wearing occlusive footwear leading to hyperhidrosis and maceration3. How do you treat it?Topical and/or oral antifungals; topical to the interdigital areas and soles as well; recurrence is frequent.An 8-year-old girl was evaluated for multiple hypopigmented macules on her face. A potassium hydroxide preparation made from a scraping of fine scale from the macules showed pseudohyphae and spores.1. What is the rash?Pityriasis versicolor: rash characterized by hypopigmented or hyperpigmented macules and patches on the chest and back, abdomen, proximal extremities, and facial cheeks, typically in older children and adolescents. Fine scales cover the lesions. Rarely pruritic.2. What causes it?The dimorphic, lipophilic Malassezia furfur, a member of normal human skin flora, and found in 18% of infants and 90-100% of adults.3. How do you treat it?Topical or oral antifungals. Topical clotrimazole, oxiconazole, or butenafine once or twice daily for two weeks. Can also use ketoconazole or selenium sulfide shampoo daily over area x 15 minutes and rinse. For severe, extensive, or recurrent cases, can use oral ketoconazole once (large dose) or daily x 7 days (smaller dose). Can recur frequently.An otherwise-healthy 6-year-old boy presents for evaluation of multiple papules on his arms, legs, and trunk. He has developed over 50 of these lesions, which are asymptomatic, over the last 4-5 months.1. What is the most likely etiology?Molluscum contagiosum: a cutaneous infection that incubates from 2-7 weeks and appear as smooth firm umbilicated pearly papules typically 2-6mm in diameter, mainly on the trunk and extremities in children.2. What causes it?A large DNA poxvirus3. How do you treat it?Varies from doing nothing (fades in several months) to topical agents (cantharidin, tretinoin, podophyllin, trichloroacetic acid), systemic (cimetidine, griseofulvin), cryotherapy, surgical curettage, and/or electrodesiccation.A 9-year-old healthy boy developed persistent warts on his hands that spread to his upper lip and hard palate.1. What are the different types of warts?5-10% of children develop cutaneous warts. Common warts are typically found on the hands. Common warts are flesh-colored, rough, and hyperkeratotic. When the superficial surface is excised, many black dots may be visible. These black dots are actually loops of capillaries. Plantar warts are found on the soles of the foot. They are often compressed against the surface of the foot due to continual weight bearing pressure and may be painful. Flat warts, or verrucae planae, are slightly raised, typically less than 3mm in diameter, and appear in crops. Their color ranges from pink to brown, and may occur on the forehead and dorsum of the hand. Filiform warts have frondlike projections and are common to the face. Condyloma acuminata are moist, soft, papillomatous warts that may occur as single or multiple lesions and are found in the anogenital region. They are most commonly seen in the sexually active adolescents. In a young child, these warts may have been transmitted through the birth canal, through spread from cutaneous warts, or they may signify child abuse.2. What is the etiology?Human Papillomavirus (over 100 serotypes).3. What are his treatment options?Over 50% of warts regress spontaneously within two years. However, untreated warts have the potential to spread and progress. When treating warts, it is imperative to protect the surrounding skin from irritation. Prior to treatment, plantar, palmar, and common warts should be pared down until the capillaries are revealed. This makes the warts more responsive to treatment. It is recommended that therapy be administered every two weeks. Liquid nitrogen or cantharidin may be used to treat common warts as well as electrodesiccation and curettage. Common warts and plantar warts may respond to lactic acid or salicylic acid treatments (over the counter topical wart medication). These warts may also be soaked in warm water and reduced with a pumice stone. Successful treatment with duct tape has also been reported. Condyloma may be treated with podophyllin applications every two weeks. However, if the warts are refractory, liquid nitrogen or CO2 laser treatment may be necessaryA 19-year-old notes diffuse, intense itching. He reports that his girlfriend has the same itching. Examination of the skin reveals interdigital lesions, with small papules, vesicles, and excoriations on the hands, and indurated nodules on the genitalia.1. What is the rash?Scabies: rash consisting of erythematous papules (trunk), burrows (commonly hands, wrists, and genitalia), and excoriations. Nocturnal pruritus is characteristic. Often involves other family members. Exposure occurs 3-4 weeks prior.2. What causes it?The arachnid mite Sarcoptes scabei car hominis.3. How do you treat it and what is the expected outcome?5% Permethrin applied at bedtime to neck to toe in adults and head to toe in infants and young children, washed off next morning. Contacts treated simultaneously; caution with pregnant females. Fomites treated wash clothing, linen, towels in hot water. May repeat Permethrin in 1 week. Pruritus can last for weeks after treatment mange with hydroxyzine and topical steroids.A 7-year-old girl is sent home after the school nurse detects head lice. She will not be permitted to return to school until the absence of infestation is documented. What treatment strategy is most likely to allow her to return to school with a minimal risk of infecting her classmates?1. What is the technical term for head lice?Human head louse = Pediculus humanus capitis or Pediculosis capitis. 2. How does it develop?Infection with head lice, spread from person-to-person by close contact or fomites (combs, clothes, hats, linen). More common in school children and females.3. How do you treat it?There are three basic treatment options for head lice for which there is some scientific evidence of efficacy: topical insecticides, wet combing, and oral therapy (though not licensed for such). The eggs (nits) attached to the hair shaft can be removed with a fine comb after soaking the hair in a solution of water and white vinegar 1:1 and wrapping in a towel for 15 minutes. The lice should be treated with 5% (Elimite) or 1% (Nix) Permethrin lotion, or Lindane 1% shampoo (over 2 yrs). A repeat treatment is recommended in 1 week. Fomites should be washed in hot water, discard combs/brushes. Eyelashes are treated with petrolatum ointment.  ATOPIC DERMATITIS Knoell KA and Greer KE.  HYPERLINK "http://pedsinreview.aappublications.org/cgi/content/full/20/2/46" Atopic Dermatitis. Pediatr. Rev. 1999; 20:46-52. Williams H.C.  HYPERLINK "http://content.nejm.org/cgi/content/full/352/22/2314" Atopic Dermatitis. NEJM. 2005. 352:2314-2324. SEBORRHEIC DERMATITIS Schwartz RA, Janusz CA, and Janniger CK. Seborrheic Dermatitis: An Overview. Am Fam Physician 2006;74:125-30. (Accessed 11/27/07 at  HYPERLINK "http://www.aafp.org/afp/20060701/125.pdf" http://www.aafp.org/afp/20060701/125.pdf.) DIAPER DERMATITIS Gupta AK, and Skinner AR. Management of diaper dermatitis. Int J Derm. 2004; 43 (11), 830834. PITYRIASIS ROSEA Hartley, AH.  HYPERLINK "http://pedsinreview.aappublications.org/cgi/reprint/20/8/266?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext=pityriasis&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT" Pityriasis. Pediatr. Rev. 1999; 20: 266 270. ACNE Zaenglein A.L. et al.  HYPERLINK "http://pediatrics.aappublications.org/cgi/content/full/118/3/1188" Expert Committee Recommendations for Acne Management. Pediatrics September 2006. TINEA Shy R.  HYPERLINK "http://pedsinreview.aappublications.org/cgi/reprint/28/5/164?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=1&title=tinea+corporis&andorexacttitle=and&andorexacttitleabs=and&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT" Tinea Corporis and Tinea Capitis. Pediatr. Rev. 2007;28;164-174. MOLLUSCUM CONTAGIOSUM / WARTS Husar K, Skerlev M. Molluscum contagiosum from infancy to maturity. Clin Dermatol. 2002 Mar-Apr; 20( 2): 170-172. Stulberg DL, Hutchinson AG. Molluscum contagiosum and warts. Am Fam Physician. 2003; 67( 6): 1233-1240. (Accessed 11/27/07 at  HYPERLINK "http://www.aafp.org/afp/20030315/1233.pdf" http://www.aafp.org/afp/20030315/1233.pdf.) Silverberg NB: Human papillomavirus infections in children. Curr Opin Pediatr 2004 Aug; 16(4): 402-9. SCABIES Stricker T, Sennhauser FH.  HYPERLINK "http://pedsinreview.aappublications.org/cgi/reprint/21/12/428?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext=scabies&andorexactfulltext=and&searchid=1&FIRSTINDEX=0&sortspec=relevance&resourcetype=HWCIT" Visual Diagnosis: A Family That Has an Itchy Rash. Pediatr. Rev. 2000; 21: 428 431. LICE Head lice infestation. Atlanta: Centers for Disease Control and Prevention, 2001. (Accessed October 24, 2007, at  HYPERLINK "http://www.cdc.gov/ncidod/dpd/parasites/lice/default.htm" http://www.cdc.gov/ncidod/dpd/parasites/lice/default.htm.) Roberts RJ. HYPERLINK "http://content.nejm.org/cgi/reprint/346/21/1645.pdf"Head Lice. NEJM 2002, 346: 1645-1650. 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