ࡱ> DFC L"bjbj =BLL$4?XXXXX333,33333 XX   3XX 3  60?+ +  2p333 333?+ 333333333 :   Peripheral Nervous System A. Sensory Receptors 1. Properties of receptors A) All receptors are transducers 1) They convert one form of stimulus into nerve energy B) All receptors transmit 4 kinds of information to the CNS 1) Modality the type of sensation a) Law of Specific Nerve Energies a receptor can respond to many types of stimuli but conveys only one sensation 2) Location 3) Intensity 4) Duration a) Some receptors experience adaptation i) Prolonged stimulus leads to a decreased firing by the receptor 2. Sensory receptors are classified on the basis of location and type of stimulation A) Location 1) Exteroceptors stimulation arising outside of the body (examples: touch, pain, pressure, and external temperature) 2) Interoceptors stimulation arising inside of the body (examples: chemical levels, stretching of tissues, and internal temperature) 3) Proprioceptors respond to internal stimuli but located only in skeletal muscle, tendons, joints, ligaments, and connective tissue covering bones and muscles a) Monitor stretch and body position B) Type of stimulus detected 1) Mechanoreceptors touch & pressure, hearing & equilibrium 2) Thermoreceptors temperature changes 3) Photoreceptors light 4) Chemoreceptors smell, taste, and blood chemicals 5) Baroreceptors stretch (blood pressure) 6) Nociceptors (free nerve ending) pain 3. General sensory receptors A) Unencapsulated bare dendrites 1) Free dendritic endings (free nerve endings) a) Located in most body tissues b) Respond primarily to pain and temperature 2) Merkel discs a) Located in the basal layers of the epidermis b) Respond to touch 3) Root hair plexus a) Nerve endings that surround hair follicles b) Respond to touch B) Encapsulated enclosed in a connective tissue capsule 1) Meissners corpuscles a) Located in the dermal papillae region of hairless skin b) Respond to touch 2) Pacinian corpuscles a) Located in the hypodermis layer of skin, periosteum, mesenteries, tendons, ligaments, joint capsules, fingertips, soles of feet, and external genitalia b) Respond to vibration and pressure 3) Ruffinis corpuscles a) Located deep in the dermis & hypodermis layers and in the joint capsules b) Respond to pressure and tendon stretch 4) Muscle spindles a) Located throughout the perimysium of skeletal muscle b) Respond to muscle stretch and they initiate the stretch reflex 5) Krauses end bulbs a) Located in connective tissue and mucosa (ex: mouth and conjunctiva of the eye) and hairless skin near body openings (i.e. lips) b) Respond to touch 6) Golgi tendon organs a) Located in tendons b) Respond to muscle and tendon stretch C) Special Sense Receptors 1) Separate cells which synapse with sensory neurons 2) Involved with all special senses except smell (olfaction) 4. Receptor Responses to Stimulus A) Generator potentials 1) Seen in unencapsulated, encapsulated, and olfactory receptors 2) Adequate stimulation of the receptor causes an impulse directly on the sensory neuron B. Receptor potentials 1. Seen in special sense receptors (except olfactory) 2. Adequate stimulation causes a receptor potential on the receptor resulting in the release of a neurotransmitter 3. The neurotransmitter then causes a EPSP on the sensory neuron C. Nerves 1. Nerves consist of parallel bundles of axons enclosed by connective tissue coverings A) Endoneurium surrounds individual axons (fibers); found surrounding the myelin sheath if one is present B) Perineurium surrounds groups of fibers bound into bundles called fascicles C) Epineurium surrounds all the fascicles; binds them together to form a single nerve 2. Direction of transmission A) Mixed nerves 1) Transmit impulses to and from the CNS B) Sensory (afferent) nerves 1) Only transmit impulses towards the CNS C) Motor (efferent) nerves 1) Only transmit impulses away from the CNS 3. All peripheral nerves are classified as Cranial or Spinal A) Cranial nerves 12 pairs *Refer to Cranial Nerves Table on the Lecture Materials webpage* B) Spinal nerves 31 pairs 1) Terminology a) Rami small branches of spinal nerves i) Both sensory & motor fibers (mixed) ii) Dorsal rami (a) Innervate deep muscles and skin of the dorsal surface of the trunk iii) Ventral rami (a) Innervate structures of the upper and lower limbs and the lateral and ventral trunk iv) Rami communicantes (a) Only seen emerging from thoracic spinal nerves (b) Contain autonomic nerve fibers v) Meningeal branch (a) Innervate blood vessels of the spinal cord and meninges b) Plexus intertwining of several ventral rami 2) Cervical Nerves (8 pairs) a) Cervical plexus (composed of portions of C1-C5) i) Mostly cutaneous nerves that innervate the skin ii) A few innervate muscles of the anterior neck iii) Phrenic nerve is the most important (a) Innervates the diaphragm for breathing b) Brachial plexus (composed of portions of C5-T1) i) Give rise to virtually all the nerves that innervate the arms (ex. brachial, radial & ulnar nerves) 3) Thoracic Nerves (12 pairs) a) Form the intercostal nerves (T1-T12) i) Innervate the intercostal muscles 4) Lumbar Nerves (5 pairs) a) The lumbar plexus arises from nerves L1-L4 b) The femoral nerve is the largest terminal nerve of this plexus i) Innervates the muscles of the anteriomedial thigh 5) Sacral Nerves (5 pairs) a) The sacral plexus arises from nerves L4-S4 b) The largest branch of the sacral plexus is the sciatic nerve i) Innervates entire leg except the anteromedial thigh ii) The thickest and longest nerve in the body 6) Coccygeal Nerves (1 pair) a) Innervates the coccyx D. Reflex and Reflex Arc 1. Reflex A) A rapid, predictable motor response to a stimulus B) Usually serves a protective function 2. Five components of a reflex arc: A) Receptor B) Sensory neuron C) Integration Center 1) Monosynaptic reflex the sensory neuron synapses directly with the motor neuron 2) Polysynaptic reflex at least 1 association neuron (interneuron) is located between the sensory and motor neurons D) Motor neuron E) Effector 3. 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