ࡱ> q` bjbjqPqP ::'HHHH8ty$(LLLL;;;[y]y]y]y]y]y]y$zh6}Hy^;yHHLLyHRLL[y[yC("L /o 6 kp[yy0y~} ~}u~}x;|ed;;;yy^;;;yDvHHHHHH (Dermatology test 2 info) 10/10/08 Skin Disease Diagnosis and Treatment Chapters 5-7 Psoriasis and Other Papulosquamous Diseases; Bacterial Infections; Sexually Transmitted Diseases Psoriasis Inflammatory rash with increased epidermal proliferation an accumulation of scale (stratum corneum). Chronic condition that waxes and wanes Appears as sharply demarcated, erythematous papules and plaques, surmounted by silvery scales. Pustules may be present. Onset is usually gradual but may come on suddenly especially after a streptococcal infection. Aggravating factors: Trauma to the skin Emotional stress Drugs- lithium Koebner phenomenon means new lesions may develop in areas of injury Psoriasis: Areas of predilection: Scalp Elbows Knees Intergluteal cleft Nails involved in approximately 50% of the cases pitted with ice-pick like depressions Psoriasis Differential diagnosis- tinea cruris, candidiasis, and seborrheic dermatitis. Therapy (allopathic)- topical steroids, topical tars, Vitamin D and Vitamin A preparations, ultraviolet light, methotrexate, cyclosporine, biologic agents. Goal is to decrease epidermal proliferation and inflammation. Psoriatic skin is often colonized with Staphylococcus aureus. Arthritis accompanies psoriasis 5 - 8% of cases. 35% of patients are genetically predisposed. The scale is adherent, silvery white and reveals bleeding points when removed (the Auspitz sign). Seborrheic Dermatitis Chronic process affecting the hairy regions of the body especially the scalp, eyebrows, and face. Characterized by indistinct margins, mild to moderate erythema, and yellowish scaling. Differential diagnosis- atopic dermatitis, psoriasis, tinea capitis, lupus erythematosus. In infants, it is expected to remit in 6 to 8 months (cradle cap) In adults, the course is chronic with remissions and exacerbations. Grovers Disease Grovers disease is also known as transient acantholytic dermatosis It is self-limited and often persists for several months to years Itching is intermittent, mild to severe, localized to lesions, and exacerbated by heat and sweating. Lesions are keratotic red-brown papules that are 1 3 mm in diameter mostly on the chest, abdomen, and back. More common in men over 40 years of age Pityriasis Rosea Pityriasis means bran-like scales. Rosea means rose color. Self-limiting, inflammatory dermatosis of unknown origin characterized by oval, minimally elevated, scaling patches, papules, and plaques that are mainly located on the trunk. Pityriasis Rosea (cont) Herald patch is the single lesion that occurs first which is followed several days to weeks by the generalized rash. Sometimes the herald patch is mistaken for a lesion of ringworm fungus Rash appears to be mediated by a cellular (type IV) immune reaction. Oval lesions on the neck and trunk follow the skin cleavage lines in a pattern that may look like a Christmas tree. Clears spontaneously within 2 months. Diagnosis is almost always clinical. Treatment is usually not necessary because it is self- limited. Most important differential diagnosis is secondary syphilis. Lichen Planus Is an idiopathic inflammatory disorder that can affect the skin, nails, hair, and mucous membranes and is characterized by: Purplish Planar (flat-topped) Pruritic Clinically, the papules are flat with subtle white dots and lines (Wickhams striae) on the surface. New lesions can develop in areas of trauma from scratching (Koebners phenomenon) Koebner phenomenon New lesions may develop in areas of injury Mucous membrane involvement is common on the buccal mucosa as a white lacey pattern demonstrating Wickhams striae. Blisters and erosions sometimes occur on the buccal mucosa, tongue, lips, and gums. Severe oral lichen planus has a 3% chance of developing into squamous cell carcinoma. Drugs that can cause lichen planus-like eruptions: Thiazides Phenothiazines Gold Quinidine Quinicrine Chloroquine Therapy For Lichen Planus Topical steroids Systemic steroids Retinoids like Soriatane Topical Retin-A for mucosal lesions Protopic Cyclosporine for severe disease Lichen Planus The course may be chronic, ranging from months to years. Patients with mucous membrane involvement usually have a more prolonged course. Scalp involvement can result in permanent hair loss Hepatitis C is present in 16% of patients with skin disease and 30% of those with mucosal involvement. Lichen sclerosus is a chronic inflammatory disease of unknown etiology which affects both skin and mucosal surfaces. Female to male ratio is 10 to 1. Women complain of chronic vulvar pruritus, dysuria, or dyspareunia that interferes with sexual activity. Men have persistent balanitis which can progress to phimosis. Lichen Sclerosus The primary lesion is an ivory white, atrophic papule with a faint pink rim. Focal hemorrhage may be seen among plaques. Keratotic follicular plugs appear on the surface (delling) The skin can have a fragile, atrophic, white and glistening appearance with a wrinkled surface Male genital lichen sclerosus is known as balanitis xerotica obliterans Atrophy encircles the anus and vaginal introitus in the female genital area in a figure 8 pattern PLEVA Pityriasis lichenoides et varioliformis acuta is also known as Mucha-Habermann disease. It is a benign, self-limited papulosquamous disorder. It can occur at any age. Most cases occur in the second and third decades. Some evidence suggests that it is a hypersensitivity reaction to an infectious agent It occurs in crops of round 2 8 mm red-brown papules, singly or in clusters Papules have a violaceous hue and adherent thin scale Individual lesions can become vesicular, hemorrhagic & necrotic usually within 2 5 weeks, often leaving post-inflammatory hyperpigmentation Lesions favor the trunk, thighs, and proximal extremities. Acute exacerbation is common and disease may wax and wane for months or years. Individual lesions may resolve, but new ones continue to appear. Therapy is directed at itch relief. Natural sunlight helps to decrease the inflammation. Impetigo Impetigo is a common, contagious superficial skin infection caused by Gram-positive bacteria, usually Staphylococcus aureus, Streptococcus pyogenes or a combination. The early lesions are pustules which quickly break to form honey-colored crusts which are the most commonly encountered clinical lesions. Some strains of S. aureus can cause bullous impetigo. Children in close physical contact with one another have a higher rate of infection. Responsible Staph may colonize the nose and serve as reservoir for skin infection. Lesions may be localized or widespread. Impetigo is common on the face. Lesions are generally asymptomatic and painless Bullous Impetigo Impetigo is the most common bacterial skin infection of children It occurs most frequently in preschool-age children Impetigo Laboratory Gram stain reveals Gram-positive cocci. Bacterial culture typically grows S. aureus. Therapy Mupiricin ointment topically (Bactroban) Oral antibiotics that target Staph General hygiene Antibacterial soaps Lever 2000, Dial, Hibiclens Changing towels, washcloths, razor, etc. daily Cellulitis Cellulitis is an infection of the dermis and subcutaneous tissues characterized by warmth, erythema, edema and pain. Group A streptococci and Staphylococcus aureus are the organisms most often responsible. Cellullitis (cont) The involved skin shows the cardinal signs of inflammation: redness (rubor) warmth (calor) swelling (tumor) tenderness and pain (dolor) In adults, cellulitis often affects the lower legs, especially when lymphatic obstruction is present. In these patients, fissures between the toes (due to tinea pedis), ulcers or erosions often serve as the initial portal of entry of bacteria. Therapy: oral or intravenous antibiotics Susceptible populations include people with: Diabetes Cirrhosis Renal failure HIV Cancer & Chemotherapy Erysipelas Erysipelas is an acute, more superficial form of cellulitis with raised, clearly demarcated borders and frequent lymphatic streaking. The most common pathogen is group A streptococci. Repeated attacks can impair lymphatic drainage, which predisposes the patient to repeated infection and permanent swelling. Folliculitis Folliculitis means an inflammation of the hair follicle. Lesions are follicularly-based pustules and papules that are sometimes tender. Common types: Bacterial (Staphylococcus aureus) Fungal Mechanical from tight clothes or persistent trauma The distribution is variable. Often the scalp, arms, legs, axillae and trunk are involved. 10/17/08 Pseudofolliculitis Barbae Pseudofolliculitis barbae is also known as razor bumps and ingrown hairs. The ingrown hair that is trapped just beneath the skin initiates an inflammatory reaction resulting in perifollicular red papules and pustules in the affected skin, most commonly in the beard area and at the occiput. This condition is a particular problem in people of African-American or Hispanic background. It is often chronic and disfiguring. The lesions can be both painful and/or pruritic. Keloid scars may develop. Tx: Avoid close shaves Furuncles and Carbuncles A furuncle (boil) is a walled-off, deep and painful, firm or fluctuant mass enclosing a collection of pus. Staphylococcus aureus is the most commonly associated organism. The incidence of methicillin-resistant Staphylococcus aureus (MRSA) is increasing, making culture and sensitivity important. A carbuncle is an extremely painful, deep, interconnected aggregate of infected, abscessed follicles. Occlusion and hyperhidrosis promote bacterial colonization. Most people have a normal immune system, but immune defects predispose a person to furuncles and carbuncles. Any hair-bearing site can be affected. Sites of high friction and sweating are most typically affected including the the waist and lower abdomen, the anterior thighs, the buttocks, the groin and the axillae. Pseudomonas Folliculitis: Hot Tub Folliculitis Improperly sanitized hot tubs can have an overgrowth of Pseudomonas that can cause erythematous pruritic papules and pustules primarily on the trunk 8 hours to 5 days after exposure. It is self-limited. Otitis Externa Otitis externa is an inflammation of the external auditory canal, usually with secondary infection. A mild self-limited form known as swimmers ear is especially common in children, often in the summer. Symptoms range from itch and irritation to severe pain Disruption of the protective wax barrier in the ear can allow for bacterial overgrowth. The usual pathogen is Pseudomonas and mixed infections with Staph and Pseudomonas. Syphilis The spirochete Treponema pallidum is traumatically inoculated into the mucous membrane or skin most often during sexual intercourse. There is a 10 90 day incubation period before the primary lesion occurs as a chancre. Secondary Syphilis The rash of secondary syphilis is an inflammatory response to hematogenously disseminated Treponema pallidum spirochete. Secondary phase starts 6 to 12 weeks after the primary chancre. Systemic symptoms include fever, headache, myalgias, arthralgias, sore throat, and malaise. Lesions are often reddish brown macules, papules, plaques, pustules or nodules Often generalized, but palm and sole involvement is characteristic White plaques may be seen in the mouth Condylomata lata are flat-topped, moist, warty-appearing lesions in the genital area. Spotty alopecia of the scalp (moth-eaten). Differential diagnosis; pityriasis rosea, drug eruptions, viral exanthem, sarcoidosis. Serologic test for syphilis(STS), rapid plasmin reagin (RPR) or Venereal Disease Research Laboratory (VDRL) will be positive and should be followed by a fluorescent treponemal antibody-absorption (FTA-ABS) test. Penicillin is the best treatment choice. Without therapy, the lesions will spontaneously resolve in 1 to 3 months. Complications: hepatitis, bone and joint disease, nephritis and central nervous system involvement. Tertiary Syphilis Granulomatous lesions (gummas) develop subcutaneously, expand and ulcerate in the skin. These lesions also occur in the liver, bones and other organs. Chancroid Chancroid is a rare sexually transmitted disease caused by Haemophilus ducreyi. A painful red papule first appears at the site of inoculation, followed by a pustule, which may rupture, forming painful genital ulcer with a bright red base. Unilateral or bilateral inquinal lymphadenopathy develops in 50% about 1 week after infection. The male to female ratio is 10 to 1. Making a diagnosis: Gram stain of the base of the ulcer shows gram-negative clumped organisms resembling a school of fish. Genital Warts ( Condyloma Acuminata ( Venereal Warts Genital warts are due to infection of genital or anal skin by the human papilloma virus. The course is highly variable. Spontaneous resolution may occur but warts may persist for long periods. Genital wart lesions may vary from person to person. Lesions may be skin colored and rough barely raised papules. The surface may be smooth, velvety and moist. Lesions may be large, cauliflower-like masses. Over 90% of cervical carcinomas are related to human papilloma virus Treatment of Genital Warts Liquid nitrogen Electrocautery and curettage Podophyllum Imiquimod Cream Herpes Simplex Virus (HSV) Herpes Simplex is an acute, self-limited, intraepidermal vesicular eruption caused by infection with herpes simplex virus. HSV is a medium-sized DNA virus that replicates within the nucleus. HSV is highly contagious and spread by direct contact with infected individuals who are often asymptomatically shedding the virus. Based on culture and immunologic characteristics (HSV) is divided into two groups: HSV-1 - responsible for most of the oral and lip herpes. Usually occurs in children with 90% of the cases subclinical. 10% of the patients have acute gingivostomatitis. HSV-2 - responsible for most of the herpes genital infections. Primary infection usually occurs after sexual contact in postpubertal individuals and affects genitals and buttocks. Produces acute vulvovaginitis or progenitalis. Primary infections are frequently accompanied by systemic symptoms that include fever, malaise, myalgia, headache, and regional adenopathy. Localized pain and burning may be so severe that drinking and eating or urinating may be compromised. Physical exam reveals indurated erythema followed by grouped vesicles on an erythematous base. Vesicles quickly become pustules which erupt, weep, and crust. Affected skin will sometimes become necrotic resulting in punched out ulcerations. Incubation period after contact with HSV is approximately 1 week (2 20 days). Primary herpes infection lasts approximately 3 weeks. Primary infections-(gingivostomatitis, vulvovaginitis) are characterized by extensive vesiculation of the mucus membrane resulting in erosion, necrosis, and a marked purulent discharge. Recurrent herpes infections are characterized by localized grouped vesicles in the same location. A prodrome of burning, tingling, and itching for 1 to 2 days is followed by a blistered eruption that continues for about 10 days. Herpes gladiatorum is traumatic herpes usually seen among wrestlers. Eczema herpeticum is a generalized cutaneous infection with HSV in individuals with predisposing skin conditions such as atopic dermatitis. It may be accompanied by severe toxic symptoms and may be fatal. Herpetic whitlow is infection of the fingers and is an occupational hazard of dental and medical personnel who do not wear gloves. HSV differential diagnosis: impetigo, contact dermatitis, superficial fungal infection. The Tzanck smear is used to confirm the diagnosis by revealing multinucleated giant cells. Allopathic therapy consists of Acyclovir (Zovirax), Valacyclovir (Valtrex), Famciclovir (Famvir). Pubic Lice Pubic lice is a contagious sexually transmitted disease. Direct contact is the primary source of transmission. Transmission can also occur from contaminated sheets and clothing. The majority of patients complain of itching. Pubic Lice cont Eggs (nits) are cemented to the hair shaft near the skin surface. Nits hatch in 8 10 days. Tx: an over-the-counter permethrin rinse (Nix Cream Rinse) applied for 10 minutes which is repeated in one week to kill nits. shave the hair to remove nits Molluscum Molluscum is a poxvirus infection of the skin characterized by discrete 2 5 mm umbilicated, flesh-colored dome-shaped papules. It is spread by direct contact or by autoinoculation Lesions can spread rapidly in patients with atopic dermatitis. Lesions may become large, numerous and disfiguring in patients with HIV. Genital molluscum contagiosum in adults can be sexually transmitted. Treatment: Curettage Cryosurgery with liquid nitrogen Cantharidin (from the blister beetle) Imiquimod Treat the underlying compromised skin barrier in patients with atopic dermatitis 10/17/08 Skin Disease Diagnosis and Treatment Chapters 8-10 Viral Infections, Fungal Infections, Exanthems and Drug Reactions Chapter 8 - Viral Infections Warts (Verruca Vulgaris) Definition benign epidermal proliferation caused by human papilloma virus On physical exam warts vary in appearance Common wart (verruca vulgaris) Filiform wart Flat wart Plantar wart Condyloma acuminatum Common Wart aka Verruca Vulgaris Physical Exam: Flesh-colored firm papule or nodule that has a hyperkeratotic surface Interrupts the skin lines Black dots are due to thrombosed capillaries Common sites are the hands, periungual skin, elbows, knees, and plantar surfaces Can occur in a linear fashion from autoinoculation Filiform Wart Is a variant of the common wart Often occurs on the face. Has finger-like projections on exam Flat Wart Has a subtle appearance These pink, light brown or light yellow papules are slightly elevated, flat-topped, and 1 3 mm. Can spread in a local region through trauma such as shaving or in a line from scratching Plantar Wart Located on the sole of the foot Infection frequently occurs at points of maximal pressure, such as over the heads of the metatarsal bones, the heels or the toes Round, single or multiple coalescing flesh-colored rough keratotic papules A mosaic wart is cluster of many warts Black dots are due to thrombosed capillaries Wart Treatments Cryosurgery Freezes the skin and causes a blister Is repeated every 2 4 weeks Acids 15% - 40% Salicylic Acid applied at home after paring the warts. May be occluded with duct tape Trichloroacetic acid 75 100% applied in the office Cantharidin -This potent blistering agent is derived from the blister beetle and is applied in the office Tretinoin (Retin-A) Is useful in the treatment of flat warts because of its exfoliating effect Podophyllin is applied in the office then washed off in 4 6 hours to prevent excessive irritation Is not used during pregnancy Can result in renal toxicity, polyneuritis, and shock Podofilox gel is applied at home bid for 3 days/week for 4 weeks. The course can be repeated up to 4 times Other Wart Treatments Surgical excision, laser, curettage, electrocautery Chemotherapeutic agents: Bleomycin or 5-Fluorouracil Treatments that induce an immune response: Imiquimod cream for genital warts: every other day for 3 consecutive days a week for 16 weeks Interferon Candida albicans intralesional injections to stimulate an immune reaction Ring Around the Wart Formation of new warts in an annular configuration (ring) at the periphery of the blister that was induced by treatment A possible complication of causing blisters during treatment Corn Some people (but not Logan Tri-8s) might mistake a corn for a wart A corn is a localized thickening of epidermis secondary to chronic pressure, friction, ill-fitting shoes. Also called clavus and heloma Occurs at pressure points On exam, corns are white-gray or yellow-brown, well circumscribed, hyperkeratotic papules or nodules Paring the surface with a scalpel reveals a translucent core with preservation of skin lines Therapy for Corn Paring down with a scalpel Softening with salicylic acid plaster (Mediplast) Reduction of trauma change of shoes, shield the sites with protective pads, rings, and orthotic devices Surgical correction of the deformity Molluscum Contagiosum Caused by a DNA pox virus that is contagious and spread by skin to skin contact and autoinoculation Lesions begin as smooth, 1-2 mm shiny. White to flesh-colored, firm papules that often are umbilicated Common childhood disease Can be sexually transmitted in adults Therapy for Molluscum Contagiosum Curettage Cryosurgery with liquid nitrogen Salicylic acid Cantharidin Imiquimod 5% cream Retin-A Cimetidine orally  HYPERLINK "http://www.theraderm.com/" http://www.theraderm.com/ ( betacaine Herpes Simplex (Cold Sores, Fever Blisters) The herpes simplex virus is a double stranded DNA virus with two different virus types (types 1 and 2) that can be distinguished in the laboratory. Type 1 is mostly associated with oral infections and type 2 is mostly causes genital infections, but either type can infect either site. Physical exam reveals indurated erythema followed by grouped vesicles on an erythematous base. Vesicles quickly become pustules which erupt, weep, and crust. Affected skin will sometimes become necrotic resulting in punched out ulcerations. Primary infections that are symptomatic may present with tenderness, pain, paresthesias, burning, gingivostomatitis, pharyngitis, lymphadenopathy, genital or rectal discomfort depending on the site of infection. Recurrent herpes infections are characterized by localized grouped vesicles in the same location. Herpetic whitlow is infection of the fingers. Herpes gladiatorum is traumatic herpes usually seen among wrestlers. Eczema herpeticum (Kaposis varicelliform eruption) is a generalized cutaneous infection with HSV in individuals with predisposing skin conditions such as atopic dermatitis. It may be accompanied by severe toxic symptoms and may be fatal. A viral culture confirms the diagnosis A Tzanck smear quickly confirms the diagnosis by swabbing the base of the blister, smearing the material on a glass slide and detecting multinucleated giant cells under the microscope Allopathic therapy consists of: Acyclovir (Zovirax) Valacyclovir (Valtrex) Famciclovir (Famvir) Incubation period after initial contact with HSV is approximately 1 week. Primary herpes infection lasts approximately 3 weeks. In recurrent infection, a prodrome of tenderness, pain, paresthesias, or burning lasting 2 24 hours precedes the blistering which can take 7 - 10 days to heal. Varicella (Chicken Pox) Chicken pox is an acute highly contagious, intraepidermal vesicular eruption caused by the varicella zoster virus. Transmission is via airborne droplets or vesicular fluid. Most cases occur in children. Adolescents, adults, and immunocompromised persons have more severe disease and are at risk for complications. After a 2 to 3 week incubation period, a 2 to 3 day prodrome of chills, fever, malaise, headache, sore throat, anorexia, and dry cough precedes the onset of a generalized pruritic vesicular eruptions. Patient is infectious for 1-2 days before the rash develops & for a further 4-5 days until the vesicles become crusted. Therapy is mainly symptomatic with the use of antihistamines for itching and Aveeno baths. There is a varicella vaccine (Varivax) that is given to children prior to exposure. Varicella cont There is varicella zoster immunoglobulin (passive immunization) that can be given as post-exposure prophylaxis to someone in a high risk group. Complications can include superinfection with Strep and Staph, pneumonia, encephalitis, and hepatitis. How a lesion changes over time (dew drop on a rose petal) -There is a simultaneous presence of lesions (vesicles, pustules and crusts) in all stages. Herpes Zoster (Shingles) Herpes Zoster (shingles) is a cutaneous viral infection generally involving the skin of a single or adjacent dermatomes. It results from a reactivation of varicella-zoster virus that entered the cutaneous nerves during an earlier episode of chicken pox. 10% to 20% of individuals develop herpes zoster during their lifetime. A prodrome of radicular pain and itching precedes the eruption. The pain can mimic a migraine, pleurisy, myocardial infarction, or appendicitis. Post-herpetic neuralgia: pain can persist long after the skin heals. Differential diagnosis: herpes simplex occurring in a dermatomal fashion. Physical exam reveals eruptions characterized by groups of vesicles on an erythematous base situated unilaterally along the distribution of a cranial or spinal nerve. The diagnosis is made clinically, but a Tzanck preparation can confirm the diagnosis. Chiropractic therapy Lauric acid 3 caps/ 3 times a day for two bottles. Ultrasound to the vesicles. Plain Ban roll-on applied to the vesicles 4 to 5 times a day. Adjust Hand, Foot, and Mouth Disease (Coxsackievirus A-16) Hand, foot and mouth disease is a highly contagious viral infection that causes aphthae-like oral erosions and a vesicular eruption on the hands and feet. The classic benign, self-limited form of this disease is associated with coxsackie A16 virus. It is usually mild, self-limited and resolves without treatment in about 10 days. Keep the child hydrated and give acetaminophen to control pain and fever. Chapter 9 - FUNGAL INFECTIONS Candidiasis (Moniliasis) Candidiasis represents an inflammatory reaction in the skin resulting from infection of the epidermis with Candida albicans. Appears as a beefy red denuded, glistening areas with surrounding satellite papules and pustules. Affects people of all ages. Patients usually complain of itching and burning. Predisposing factors Infancy Moisture Pregnancy Oral contraceptives Systemic antibiotic therapy ( kill the bacteria that compete with yeast Diabetes mellitus Skin maceration Topical and systemic steroid therapy Decreased cell-mediated immunity Candida Balanitis Candida balanitis is a localized, acute infection of the foreskin and glans penis caused by Candida. Occurs more frequently in uncircumcised men than in circumcised men. Diabetics are at greater risk. There are pinpoint red papules evolving into pustules on the glans and coronal sulcus with a pasty macerated debris under the foreskin. Candidiasis (Diaper Dermatitis) Diaper dermatitis is a term that encompasses a number of skin conditions, causing red scaly rashes on the diaper area. Diapers occlude the skin, leading to skin maceration and predisposing to skin infection and inflammation. Satellite pustules are the hallmark of Candida dermatitis. Candidiasis of Large Skinfolds (Candida Intertrigo) Yeast thrive in intertriginous areas where skin touches skin Large skinfolds retain heat and moisture, providing the environment suited for yeast infection Predisposed individuals include older women with pendulous breasts, obese people with overhanging skinfolds below the abdomen, in the groin and rectal areas, and in the axillae. Satellite papules & pustules dot the normal skin just beyond the plaques Thrush (Oral Candidiasis) Thrush is caused by infection of the oral epithelium with Candida albicans. Appears as white patches that easily scrape off and white curd-like papules that resemble cottage cheese Common in newborns, denture wearers, patients on intraoral steroids and broad spectrum antibiotics and immunosuppressed people Diagnose with a KOH or culture Treat with topical or oral antifungals Tinea Versicolor Tinea versicolor is a superficial infection caused by the lipophilic yeast Pityrosporum orbiculare (Malassezia furfur) that results in altered pigment in the epidermis. The lesions appear as finely scaling patches that can be pink, tan, brown or white mostly on the neck, trunk, and upper arms. Any age group may be affected, but the disease is most common in adolescence and young adults. Occasionally associated with mild pruritus, but most often is asymptomatic. The organism cannot grow on routine fungal culture; therefore, the diagnosis is made by KOH examination. The KOH resembles spaghetti and meatballs. Treatment: Selsun Shampoo, Nizoral Shampoo, prescription antifungal creams and pills Pityrosporum (Malassezia) Folliculitis An infection of the hair follicle caused by the yeast Pityrosporum orbiculare (Malassezia furfur), the same organism that causes tinea versicolor. Follicular occlusion may be a primary event, with yeast overgrowth as a secondary occurrence. Diabetes mellitus, broad-spectrum antibiotics or corticosteroids are predisposing factors. Tinea of the Nails (Onychomycosis) Definition onychomycosis and tinea unguium are synonyms for infection of the nail with dermatophytic fungi 15 - 20% of Americans aged 40 60 have onychomycosis The onset is slow and insidious and often asymptomatic, but may cause pain in that digit, problems trimming the nail, discomfort when wearing shoes, and embarrassment Oral antifungal medications are more effective than topical ones 10/24/08 Fungal Nail Infection Distal Subungual Onychomycosis: involvement of the undersurface of the distal nail with accumulation of subungual debris resulting in a white, yellow, or brown discoloration White Superficial Onychomycosis: caused by surface invasion of the nail plate. The nail surface is soft, dry and powdery, and can easily be scraped away. Proximal Subungual Onychomycosis: infection of the proximal nail plate is a marker of HIV infection Candida Onychomycosis Candida can cause infection of the nails It is seen almost exclusively in chronic mucocutaneous candidiasis a rare disease It generally involves all of the fingernails The nail plate thickens and turns yellow to brown Angular Cheilitis (Perleche) Angular cheilitis is a chronic recurring inflammation at the angles of the mouth. Saliva macerates and irritates this small intertriginous area leading to eczema, fissuring and secondary bacterial and yeast infections. Cutaneous Fungal Infections Dermatophytes are fungal organisms that infect the skin. They are keratinophilic they feed on keratin. Common clinical lesions are scaling, erythematous papules, plaques and patches with a serpiginous (worm-like) border. Dermatophytes 3 genera * Microsporum * Trichophyton * Epidermophyton The word tinea (Latin for worm) is used to denote a superficial fungal infection. The word tinea is followed by a qualifying term that denotes the location. Fungal infections based on area of body: Tinea of the foot (tinea pedis) Tinea of the groin (tinea cruris) Tinea of the body (tinea corporis) Tinea of the face (tinea faciei) Fungal Infections Patients often present with: a scaling rash pruritus a history of exposure to infected persons or mammals such as dogs, cats, cattle. Differential Diagnosis: nummular eczema which are coin-shaped lesions usually multiple located on the extremities. pityriasis rosea - oval, minimally elevated, scaling patches, papules, and plaques located on the trunk. impetigo - characterized by vesicles, pustules, and crusts in annular lesions. erythema annulare centrificum characterized by negative KOH. Scales are inside an elevated border. granuloma annulare characterized by indurated border without scaling and is KOH negative. Laboratory Tests: KOH preparation findings of hyphae is diagnostic of either dermatophytic or candidal infections. Fungal culture of scales can distinguish between dermatophyte and candidal infections. Treatment of Fungal Infections Topical or oral antifungal agents. Natural Therapy: Topicals: tea tree oil, camphor, garlic oil, oregano oil. Orals: garlic-allicin, Echinacea and Goldenseal (450 mg/day) to boost the immune system, Astragulus (300mg/day) to boost white cell count, Caprylic acid (antifungal) - twice the recommended dosage Acidophilus/bifidus-normal flora Diet is very important in the treatment of fungal infections. The patient must stay away from all sugar and sugar products. The patient should consume mostly green vegetables. Exercise to get the nutrients to the target tissue. Tinea of the Feet (Tinea Pedis) Tinea Pedis may present as: interdigital macerated scaling process between the toes. diffuse plantar scaling: dry and scaling skin especially on the soles of the feet extending into the sides. vesiculopustular form which appear as vesicles and pustules on the sides and instep of the feet. Differential diagnosis of tinea pedis: dry skin contact dermatitis dyshidrotic eczema pustular psoriasis. Tinea of the Groin (Tinea Cruris, Jock Itch) Tinea Cruris also known as jock itch, is a fungal infection located in the groin area that appears as an elevated serpiginous border with scaling and a tendency for central clearing. Scrotum is seldom involved. Differential diagnosis of tinea cruris: candidiasis yeast infection intertrigo or simple irritant dermatitis most commonly found along the inguinal folds of obese persons psoriasis seborrheic dermatitis. Tinea of the Body (Tinea Corporis) Dermatophyte infection of the body, trunk, and limbs is called tinea corporis. In classic ringworm, lesions begin as flat, scaly papules which slowly develop a raised border that extends at variable rates in all directions. The advancing, scaly border may have a red, raised border with papules and vesicles The central area has less scale as the active border progresses outward - central clearing Tinea of the Face (Tinea Faciei) Tinea Faciale characterized by an erythematous, usually asymmetric, eruption on the face with at least some borders that are well demarcated and often serpiginous. Differential Diagnosis: seborrheic dermatitis lupus erythematosus Tinea of the Hand (Tinea Manuum) Tinea Manuum often involves only one hand and appears as diffuse scaling of the palmar surface. Tinea Manuum almost always co-exists with Tinea Pedis as the one hand, two feet syndrome. Differential diagnosis: chronic irritant contact dermatitis, psoriasis. Tinea Incognito Tinea incognito is a localized cutaneous fungal infection, the appearance of which has been altered by application of topical corticosteroids. -cortisone will reduce the itch of a fungal infection, but will not help fight the fungal infection Tinea of the Scalp (Tinea Capitis) Definition tinea capitis is a superficial fungal infection of the scalp most commonly causes by Trichophyton tonsurans Lesions vary from noninflamed scaling that looks like seborrheic dermatitis, or broken off hairs that is called black dot ringworm patches to inflamed, pustule-studded plaques (kerion) that may leave scars. Kerion = lot of inflammation with pustules If see kid with inflammation and pustules, then think tinea capitis Diagnosis is confirmed by KOH and fungal culture Treat with systemic antifungals Griseofulvin Terbinafine (Lamisil) Itraconazole (Sporanox) Tinea of the Beard (Tinea Barbae) Tinea barbae is a dermatophye infection of the skin and hair in the beard area which can have 2 clinical patterns: Annular plaques resembling ringworm Deep follicular infection with pustules and draining nodules Chapter 10: Exanthems and Drug Reactions Non-Specific Viral Rash An exanthem is a rash that occurs as a sign of a systemic disease. A viral exanthem is a rash that arises due to a viral infection. Viral exanthems may have different presentations and frequently are a generalized eruption composed of erythematous macules and papules usually preceded by a prodrome of fever and constitutional symptoms. Examples of viruses capable of causing non-specific viral exanthems: non-polio enteroviruses(enterovirus, coxsackievirus, echovirus) Epstein-Barr virus human herpes virus-6 human herpes virus-7 parvovirus B-19 respiratory viruses (rhinovirus, adenovirus, parainfluenza virus, respiratory syncytial virus, influenza virus) Roseola Infantum Roseola infantum is a viral exanthem characterized by high fever followed by the abrupt appearance of a diffuse rash as the fever resolves. Roseola infantum occurs in infants from the ages of 6 months to 3 years with a peak incidence at 6 months. Within 2 days of the fever breaking, small pink almond-shaped macules occur on the neck, the trunk, the proximal extremities and face. Erythema Infectiosum (Fifth Disease) Erythema infectiosum, also known as fifth disease or slapped cheek syndrome is a common viral exanthem that causes bright red cheeks and lacy erythema of the arms. Erythema infectiosum occurs in the winter and spring and is associated with community outbreaks. It is caused by parvovirus B19 and is transmitted via respiratory secretions, blood, or vertically from mother to fetus. There is facial erythema the slapped-cheek appearance. The slapped-cheek appearance fades in 4 days. Approximately 2 days after the slapped-cheek rash, lacy erythema in a fish-net pattern begins on the proximal extremities and extends to the trunk and buttocks, fading in 6 14 days. Palms and soles are spared. Most infections are self-limited without adverse sequelae. Kawasaki Disease Kawasaki disease, also known as mucocutaneous lymph node syndrome, is an acute multisystem vasculitis of unknown origin that occurs in infants and young children. Cardiovascular involvement is the major cause of morbidity. Most common in Japan No diagnostic test exists conjunctival injection uveitis lips are red, dry, fissured, cracked and crusted strawberry tongue Diagnosis of Kawasakis is based on having 5 of 6 signs: Fever of unknown origin for more than 5 days Bilateral conjunctival injection Changes of the lips and oral cavity Cervical lymphadenopathy Polymorphous exanthem with vesicles or crusts Changes of the peripheral extremities Around 2 5 days after the onset of the illness, the palms and soles become red and swollen. 10 14 days after the onset of the fever, the skin peels off in sheets beginning around the tips of the digits The rash is polymorphous has many forms...macules, papules, urticarial-;like lesions, and erythema multiforme-like lesions Treatment: Intravenous immune globulin Aspirin methylprenisolone Cutaneous Drug Reactions The two most common appearances of drug eruptions are hives and morbilliform rashes. A morbilliform drug rash appears as a generalized eruption of erythematous macules and papules, often confluent in large areas. There are no laboratory tests available to identify the responsible drug, thus reliance is placed on the history. Two variables to consider in the history: the temporal relationship between the initiation of the drug and the onset of the rash the likelihood that a given drug is likely to cause a drug eruption. Remember to ask about over-the-counter medications. Treatment: Discontinue the offending drug Antihistamines to control the itch Oral and topical steroids to decrease the inflammation Common Causes of Drug Reactions Antibiotics: Penicillins Cephalosporins Sulfa drugs Diuretics: Furosemide Hydrochlorothiazide Nonsteroidal anti-inflammatory drugs Blood products Urticaria (Hives) Hives are skin lesions that are easily recognized. They appear as edematous plaques, often with pale centers and red borders. By definition, an individual hive is transient, lasting less than 24 hours, although new hives may develop continuously. Therapy Avoid the responsible allergen Antihistamines Exfoliative Erythroderma There is generalized redness and desquamation The reaction is potentially life threatening Fixed Drug Eruptions Single or multiple, round, sharply demarcated, dusky red plaques appear soon after drug exposure and reappear in exactly the same site each time the drug is taken. Acute Generalized Exanthematous Pustulosis Characterized by multiple tiny superficial pustules over most of the body. The most common drugs are the antibacterial agents (mostly penicillin) There is a short interval between drug ingestion and the eruption (5 days) and resolution occurs in less than 15 days. Toxic Shock Syndrome Toxic shock syndrome is an acute toxin-mediated multisystem disease resulting in high fever, diffuse erythroderma, mucous membrane hyperemia, and profound hypotension. The toxins are produced by Staph and Strep bacteria Originally diagnosed in women who used high- absorbency tampons. Treatment: care in the intensive care unit and antibiotics  SHAPE \* MERGEFORMAT  Chapters 11-12: Skin Disease Diagnosis and Treatment Hypersensitivity Syndromes and Vasculitis Infestations and Bites Erythema Multiforme Erythema multiforme is a relatively common, acute often recurrent - inflammatory disease characterized by target-shaped skin lesions. It is characterized clinically by a variety of lesions, including erythematous plaques, blisters and target lesions. Target or iris lesions have a central dark red purpuric or blistered area surrounded by a pale edematous zone surrounded by a sharp discrete ring of erythema. Recurrent disease is caused most often by herpes simplex infection. Mycoplasma pneumoniae infection and upper respiratory tract infections are precipitating events in some patients. This disorder most often affects older children and young adults. The lesions are pruritic and may have a burning sensation. Characteristically, the distribution of lesions favors the extremities, particularly the palms and soles, and is strikingly symmetric. Target lesions are often present and diagnostic. Stevens-Johnson Syndrome Stevens-Johnson syndrome is a severe blistering syndrome involving the skin and at least 2 mucous membranes. It is similar to erythema multiforme and is usually caused by drugs or infection. Toxic Epidermal Necrolysis Toxic epidermal necrolysis is a rare life-threatening mucocutaneous disease characterized by widespread blistering and sloughing of the skin and mucous membranes. The cause is unknown, but drugs and infection can precipitate toxic epidermal necrolysis. Most patients develop diffusely red sunburn-like tender skin with scattered target lesions and bullae. Bullae quickly coalesce, resulting in widespread skin sloughing. Gentle lateral pressure easily produces epidermal detachment (Nikolskys sign) Therapy for Erythema Multiforme, Stevens-Johnson Syndrome & Toxic Epidermal Necrolysis Treat infection, if present Discontinue responsible drug, if any If significant areas of skin are denuded, hospitalize the patient in a burn unit, give supportive care, intravenous immunoglobulin is beneficial and sometimes systemic steroids are used briefly Erythema Nodosum Erythema nodosum is a panniculitis characterized by symmetrical pink to dusky red tender nodules on the extensor surface of the lower legs. Women out-number men 6:1 Thought to be due to a hypersensitivity reaction to a variety of antigenic stimuli like streptococcal infections and sarcoidosis. Treatment: Identify and treat the associated diseases and infections Discontinue precipitating medications Rest Compressive bandages Non-steroidal anti-inflammatory drugs like indomethacin and naprosyn Cutaneous Small Vessel Vasculitis (Hypersensitivity Vasculitis) When the skin is affected by vasculitis, lesions are elevated (palpable) because of inflammation and edema and purpuric because of extravasation of blood from damaged blood vessels. The result is purpuric papules (palpable purpura) Lesions are mostly located on the legs Vasculitis Causes of cutaneous vasculitis include Infections and Sepsis Chemicals Food allergens Connective tissue disease Malignancies Drugs Idiopathic Treatment consists of removal of precipitating agents appropriate treatment of coexistent disease Henoch-Schonlein Purpura Henoch-Schonlein purpura is a leukocytoclastic small vessel vasculitis Characterized by palpable purpura mostly on the buttocks and lower extremities (but they may appear on the upper body) Other findings include joint pain, abdominal pain and glomerulonephritis. 90% of affected patients are younger than 10 years old. The peak incidence is during the winter months. Commonly follows an acute respiratory illness by 1 2 weeks, suggesting that infection is an important factor Schambergs Disease (Schambergs Purpura) Schambergs disease is characterized by petechiae and brown purpuric (rusty colored) patches, occurring most commonly on the lower extremities It is a lymphocytic capillaritis suggesting a cell-mediated hypersensitivity reaction It is also known as pigmented purpura. Patients develop multiple distinct orange-brown, pinhead-sized cayenne pepper macules with numerous petechiae. Lesions occur symmetrically on the lower extremities and sometimes on the upper body. The condition is confined to the skin (no internal disease) and the vast majority of patients improve with time. Sweets Syndrome Sweets syndrome is an acute inflammatory eruption characterized by multiple pink to red tender plaques, associated with fever, malaise, and leukocytosis Sweets syndrome is paraneoplastic (hematological malignancy or solid tumors) in 15 20% of patients and may precede the malignancy by up to 6 years. Sweets syndrome lesions erupt acutely and can be painful. They are plum-colored and Juicy (pseudovesicular) in appearance. They can occur on any surface, but tend to occur on the head, neck, legs, arms, dorsal hands, and fingers Panniculitis Panniculitis refers to a group of disorders that cause inflammation of the subcutaneous fat. Panniculitis manifests as discrete pink to deep red, tender nodules and firm plaques. Erythema nodosum is a form of panniculitis Chapter 12: Infestations and Bites Scabies Scabies is an infestation of the epidermis with the Sarcoptes scabiei var. hominis mite. Contagious - family and friends often itch. Generalized itching is the main complaint, especially at night. Rash appears 2 6 weeks after exposure. The itching and inflammation are thought to results from a hypersensitivity reaction to the foreign material (mite, eggs, and feces). Itching may persist after adequate treatment due to allergic response to dead mites, eggs, and feces. SCABIES Physical exam: The diagnostic finding is a burrow which appears as a 1-2 mm wide delicate, white, linear, curved or S-shaped superficial, thread-like line especially between fingers small vesicles, papules and excoriations favors finger webs, wrists, sides of the hands and feet, the penis, buttocks and scrotum. More Scabies info In infants, vesicles may also be present particularly on the palms and soles. Nodules may be present in the axillae and on the penis Norwegian scabies is the crusted variant that occurs in immunocompromised and institutionalized patients and in those with an altered mental status. The lesions in Norwegian scabies contain numerous mites. Scabies Prep Scrape a burrow with a #15 blade, apply scraping to a slide with mineral oil, view the mites, eggs, or scabelum (feces) under microscopy Scabies Therapy 5% Permethrin cream (Elimite,Acticin) overnight to the entire body surface area. Repeat in one week. Ivermectin 0.1 0.2 mg/kg as a single dose. Repeat in 2 weeks. Treat the contacts Wash the clothes in hot soapy water Lice (Pediculosis) Lice are flattened, wingless insects that infest hair of the scalp, body and pubic region. Lice attach to the skin and feed on human blood. Nits are lice eggs attached to the hairs. Treatment (for head lice) Permethrin rinse 1% (Nix creme rinse) Botfly Myiasis Myiasis is an infestation of the body tissues of animals or humans by the larval stage of non-biting flies. Dermatobia hominis causes human botfly infestation. Botfly life cycle: The female botfly glues her eggs to the abdomen of a mosquito or tick which deposits the larvae while biting or feeding At maturation, the larva exits the body and drops to the ground and matures into an adult fly. Skin findings of Myiasis The tender red nodule is about 2 5 mm in diameter Lesions are typically found on the scalp, face or upper arms or chest The larval breathing tube is mobile and can be seen opening and closing within the skin about once every minute An enlarged cyst-like structure enlarges over days to weeks and is known as a warble Myiasis Another less common type of myiasis is tungiasis, caused by a red-brown sand flea called Tunga penetrans Tungiasis is seen on the soles, toe webs, and ankles of travelers returning from Africa or Central or South America Bee Stings Honey bees are the most common source of insect stings and can cause severe allergic reactions The stinger of the honey bee separates from the bees abdomen while stinging and remains embedded in the vertebrates tissue The stingers of other bees and wasps do not detach The stinger should be removed as fast as possible. A delay of just a few seconds in removing the stinger leads to greater venom delivery A hive or raised pink wheal with a central pinpoint red punctum appears minutes after the sting and lasts for about 20 minutes. Angioedema may occur, which is a localized reaction that appears thick, hard and edematous over an area as large as 10 50 cm Bee and Wasp Stings Preloaded epinephrine (adrenaline) syringe kits are available (EpiPen Auto-Injector, Ana-Kit) Insect that Bite Insects that bite usually out of hunger include mosquitoes, fleas, bedbugs, and lice. Spiders, ticks, and chiggers are other arthropods that sometimes attack human skin. There is a delay between the bite and the itching that follows. Bedbug Bedbugs can live along the seams of mattresses and furniture and wait for their meal to arrive Insect Bite Reactions It is not necessary for other housemates to be affected Not all people are sensitive to the bite Not all people attract insects equally Chiggers - favor the legs and areas of tight fitting clothes Black Widow Spider Bite The adult female black widow spider (Latrodectus mactans) is about 3 4 cm in length and has a shiny, fat abdomen resembling a large grape. The black widow spider has a characteristic red hourglass-shaped marking on the ventral surface of the abdomen The clinical appearance is variable; typically erythema or swelling occurs at the bite site. Cramping abdominal pain is common and is the classic presenting complaint. Brown Recluse Spider Bite The bite of the brown recluse spider (Loxosceles reclusa) may cause necrotic skin lesions The spider is yellow, tan or brown in color and can be identified by a dark brown, violin-shaped marking on its cephalothorax (hence the name the fiddle-back spider). The body length is 10-15 mm and the leg and is about 25 mm The bite site may show localized hive-like reaction with minimal redness and swelling early in the course. A cyanotic color, followed by expanding necrosis of the skin develops within days. Tick Bites -Ticks burrow their head into the skin Lyme Disease Lyme disease is a tick-borne disease caused by the spirochete Borrelia burgdorferi. The cutaneous eruption of Lyme disease is called erythema migrans which is a slowly enlarging ring of erythema that may last 2 3 weeks. Rocky Mountain Spotted Fever Rocky Mountain spotted fever is a potentially lethal disease caused by Rickettsia rickettsii, a short Gram-negative bacteria. The infection is characterized by an acute onset of fever, a severe headache, myalgia, vomiting and a petechial rash that starts on the wrists and ankles, involves the palms and soles, then becomes generalized. The rash does not occur at all in about 15% of cases. Flea Bites The typical eruption for flea bites is papules on the legs. Initially, tiny red dots or bite puncta may be seen, often grouped around the ankles. Cutaneous Larva Migrans (Creeping Eruptions) Cutaneous larva migrans is caused by the aimless wandering of the hookworm larvae within the skin. The lesions typically begin about 3 weeks after a beach vacation in the Caribbean, Africa, South America, southeast Asia, or even the southeastern USA. The larvae can penetrate the skin when humans walk on moist feces-contaminated sand. A serpiginous red to purple lesion with a 3 mm wide tract is characteristic Fire Ant Stings Fire ants have prominent inward-curving jaws and stingers on their tails. The bite causes a painful pustular lesion. The classic lesion is two pinpoint red dots (the bite) surrounded by a ring of pustules (the stings) Swimmers Itch (Schistosomiasis) Swimmers itch is a pruritic inflammatory response to the larvae released from a snail that accidentally penetrate human skin. The parasites are obtained while swimming in fresh-water lakes. As the water evaporates from the swimmers skin, the larvae penetrate causing highly pruritic, red, edematous, bite-like papules and occasionally pustules Lesions are in areas not covered by the swimming suit. The eruption is self-limited Seabathers Eruption Seabather's eruption. A common problem in the Caribbean. Nematocyst-bearing larvae may be trapped under the bathing suit and produce an intensely itching and painful papular eruption. It is advisable to bring a bottle of vinegar to the beach, because rubbing the affected area or washing with fresh water can cause nematocysts to discharge. Saturating the area with vinegar immobilizes unspent nematocysts. Animal and Human Bites Cats have long sharp teeth Wounds can become infected Tendons, nerves, and vessels can be damaged and tissue can be crushed A bite from an adult human has a greater arch width than that of a toddler Rabies can be transmitted from a wild animal or an unvaccinated domestic animal     the guy with the bow tie Polygonal Papules (Penis) Tinea of the hand (tinea manuum) Tinea of the scalp (tinea capitis) Tinea of the beard (tinea barbae) Tinea of the nails (onychomycosis) "#GH; < Q R e f u Z [ e } wkh:'h:'CJ\aJh:'h:'CJ\aJh:'h:'6CJ]aJh:'h tCJaJh:'h:'5CJaJh:'h:'CJaJh:'h:'5CJ\aJh:'h:'CJaJh th:'5CJaJh:'h:'>*CJaJh:'h:'>*CJ aJ h:'CJaJh#[CJaJ*#& N $ 9 O c u & F gd:' h^hgd t & F gd:' & F gd:' gd:' $ a$gd:' $ a$gd#[ $ a$gd#[  4 Z [ e * \ & F gd:' & F gd:' & F gd:' & F gd:' gd:' & F gd:' & F gd:'=>O:]^ & F gdk8gdk8 & F gdk8 gd t & F gdk8 gdk8 & F gd:' gd:' & F gd:'=>O'()78hi   @A}~BCOPVh:'h:'5CJaJh1Hh1HCJaJ"jh.CJUaJmHnHuh:'h:'5CJ\aJh:'h:'CJ\aJh th t5h th t5\h:'h:'CJ\aJh:'h:'CJaJh:'CJaJh:'h:'CJaJ2^()7BI8^8gdk8 & Fgdk8 & Fgdk8 & Fgdk8h^hgd1H & F gdk8 & F gdk8gdk8 & F gd:'gd:' & F gdk8I)3BGQ\hi  T & Fgdk8h^hgdk8 & Fgdk8 & Fgdk8 & Fgdk8gdk8 & Fgdk8@A@~CDOPV0  & Fgdk8h^hgdk8 & Fgdk8 & Fgdk8gdk8 & Fgdk8- [ !!/!0!!!Q"R"b"c""""""9#B### $ $$$$$$$$%%&& ' ''''K(L(Y(((()L)M)))))*嬠hvWCJaJh1Hh1H5CJaJh1HCJaJh:'h:'CJ\aJh:'h:'6CJ]aJh1Hh:'5CJaJh:'h:'CJaJh:'CJaJh:'h:'CJaJh.CJaJ< #d/!0!!!"!"Q"R"c"""""" & Fgdk8 & Fgdk8 & Fgdk8 & Fgdk8gdk8 & Fgdk8"#D#L#u#### $ $$$$$$$6%F%U%f%%%x& & Fgdk8 & Fgdk8gd1H & Fgdk8gdk8 & Fgdk8 & Fgdk8 & Fgdk8x&&&&&&&& '''''K(L(Y((((()) & F!gdk8 & F!gdk8 & F gdk8 & Fgdk8 & Fgdk8 & Fgdk8 & Fgdk8gdk8 & Fgdk8)L)M))))***N+s++++++Z,,-}--&. & F&gdk8 & F%gdk8 & F$gdk8 & F#gdk8$a$gdvW & F"gdk8gdk8 & F!gdk8**+++Z,o,,,|-}-%.&.../'/_/k///011t11111111111222233334ƻwh.CJaJh.h.6CJ]aJh.h.CJaJh.h.CJaJh.h.CJ\aJh:'h:'CJ\aJh:'h:'CJaJh:'h:'6CJ]aJh:'h:'6CJ]aJhvWh:'CJaJh:'h:'CJaJh:'CJaJ+&..'////0f0011^1111@2222$3d333 & F, xgdk8 xgdk8 & F+gdk8 & F*gdk8 & F)gdk8 & F(gdk8gdk8 & F'gdk834S4z4444S5'6(6Q66677j777788 & F1 xgdk8 $ xa$gd. & F0 xgdk8 & F/ xgdk8 & F. xgdk8 xgdk8 & F- xgdk84'6(667777778'9(99999999:::;;;;;<<2<3<u=v=w=====չչ럔{vnbhvWh.5CJaJhk8h.5 hk85hvWh.CJ aJ hvWh.5CJ \aJ h1H5>*CJaJh1Hh.5>*CJaJh1Hh.5CJaJ jh.h.CJaJh.h.6CJ]aJh.h.CJaJh.h.CJaJh.CJaJh.h.CJ\aJ&89'9(9<99994::::;>;m;;;$ & F4 xa$gd.$ & F4 xa$gd. $ xa$gd.$ & F3 xa$gd. xgd. & F2 xgdk8 & F2 xgdk8 xgdk8 & F1 xgdk8;;;;<<<3<<<u=v===:>}>>m?n? $ xa$gd. $ Va$gd. & F6 Vgdk8 $ Va$gd.$ & F5 Va$gd.$ & F5 xa$gd.$ & F5 xa$gd.====9>>>>>>>>m?n?QARABBByCzCCCCDDDEE&F'F2FGG&GGG"H#H-HHHIIIiJqJrJJJJJJJ휐hZIhZICJaJhZIhZI>*CJaJhZIhZI>*CJ aJ hZICJaJh1Hh.5>*CJaJh1Hh1H5CJaJh.h.CJaJh.h.>*CJaJh.h.5CJaJh.CJaJh.h.CJaJ4n??`@@@QARAAABByCzCCDDEEiEE&F & F< xgdk8 & F; xgdk8 & F: xgdk8 & F9 xgdk8 & F8 xgdk8 xgdk8 & F7 xgdk8&F'F2FkFFGG&GhGGGH"H#H-HHHH#IlI$ & F@ xa$gd.$ & F? xa$gd. & F> xgdk8 & F> xgdk8 xgdk8 & F= xgdk8 $ xa$gd.lIIIIIIJJiJrJJJKK KlKK & FB xgdZI xgdZI $ xa$gdZI $ xa$gdZI$ & FA xa$gd.$ & FA xa$gd. $ xa$gd.$ & F@ xa$gd.JJJJJJKKK KKKLL2M3MAMMMM~NNNOOOOO0P1P2P8PPPPPPP=Q>Q?QSQQQQVRcRRRRSº훪h>hZI5CJaJ h>h>h>CJaJh>hZI>*hZIhZI>*hZICJaJhZIh1HCJaJhZIhZICJaJhZI>*CJaJhZIhZI>*CJaJhZICJaJhZIhZICJaJ2KKKKKKKL LfLLLL2M3MAMaM{MMMMM&NN & FE xgdZI & FD xgdZI & FC xgdZI xgdZI & FB xgdZINNN-OxOOOOOOP0P1P8PPPPP=Q>QSQ xh`hgd> & FH xgdZI & FG xgdZI VgdZI xh^hgd1H & FF xgdZI xgdZISQQQR RVRRRRSCSnSSS"T#T8TT & FI xgd> xgd> & FM VgdZI & FM VgdZI & FL VgdZI VV`Vgd> & FK VgdZI VgdZI & FJ VgdZISS"T#T8TTTTVVVVWWWWXXXXFYHYIYUYnYpYqYrYYYYYY߱ߡߍ{n` jhZIhZICJaJhYhZI0JCJaJ#jhYhZICJUaJjhZICJUaJh>CJaJh1HCJaJh>hZI>* hZI5hZIhZICJaJh>CJaJhZIh>CJaJhZIh>CJaJhZICJaJhZIhZICJaJhZIhZI6CJ]aJ TTTT6UUUU>VVVVVVfWWWWWXpXXX & FP xgdZI & FO xgdZI & FN xgdZI xgdZI VgdZI & FI xgd>XXXXX YY,Y4YFYYYYZZZZC[[[\\ & FS VgdZI & FR VgdZI VgdZI & FQ xgdZI Vgd> xgdZIYYYZZ[\\\ ]]:]L]]]n^o^__```$b%bb cch>5CJaJhZIh>CJaJh>h>6CJ]aJh1Hh1H5CJaJh>h>CJaJh>CJaJh>hZICJ\aJhZIhZI>*CJaJhZICJaJhZIhZICJaJhZIhZICJ\aJhZIhZICJaJhZIhZI5CJaJ*\ ]:]]n^o^^N_n______0````^aaa%b & FW VgdZI & FV VgdZI & FU VgdZI & FU VgdZI VgdZI & FT VgdZI%bbfccd%ddee\eeeeNffgg\ggg & F[ Vgd> VgdZI & FZ Vgd> Vgd> Vh^hgd> Vgd1H & FY Vgd> & FX VgdZI\e`eeeeeegggh>CJaJh>h>6CJ]aJh>h>>*CJaJh>h>CJaJh>h>CJ\aJh>h>>*CJ\aJh>h>CJaJh>h1HCJaJhZIh>CJaJh>CJaJ6g & F^ Vgd> & F] Vgd> Vgd> & F\ Vgd> VgdZI & F[ Vgd>kdlllmm+m3m & Fa Vgd> Vgd> VgdZI & F` Vgd>poopqppppq}q/rxryrrrHsss ttttFuu & Ff Vgd> & Fe Vgd> & Fd Vgd> VgdZI & Fc Vgd> Vgd>tttuuvvw:wQwSwdwPxQxtx~xyz z z"zAzzzj{{{{{{|||}}}~~~~~~~~~  ԬߊhD;h>CJ\aJhD;6CJ]aJh>6CJ]aJh>h>>*CJaJhBc`CJaJh1HCJaJh>h>5CJaJh>h>CJaJh>CJaJh>h>6CJ]aJh>h>CJaJ0uuu[vvvvwwwPxQxtxxyyyzzzz $ Va$gdBc` & Fi Vgd> & Fh Vgd> Vgd> & Fg Vgd> VgdZI & Ff Vgd>z z"zz{j{{{{|b|||||1}}}}~ & Fm Vgd~en & Fl Vgd~en & Fk Vgd~en VgdZI & Fj VgdZI & Fj Vgd> Vgd> $ Va$gdBc`~@~~~~~  \7XYZl & Fp Vgd~en & Fo Vgd~en VgdD; & Fn Vgd~en VgdZI Vgd> & Fm Vgd~enXYZklmizҁہ!>ނ߂Xf΃σ/BDEKLlr҄لȺ㱥бЌк㥱h8 CJ\aJhD;5CJ\aJhD;hD;>*CJ\aJhD;hD;CJ\aJhD;CJ\aJhD;hD;5CJ\aJh1HCJaJhD;CJaJhD;hD;CJaJhD;hD;CJaJ"jh1HCJUaJmHnHu3iҁ!ނ߂XσA & Ft Vgd4 & Fs Vgd4 & Fr Vgd4 & Fq Vgd~en VgdD; VgdZI & Fp Vgd~enل݄&489DVb]^_LJʇʈˈ˦vh`WhBsCJ\aJhBsCJaJhBshBs>*CJ\aJhBshBsCJaJhBshBsCJaJhBshBsCJ\aJh hBs5>*CJaJh hBs5>*CJ\aJhD;hD;CJaJhD;hD;CJaJhD;CJaJhD;hD;>*CJ\aJh8 CJ\aJhD;CJ\aJhD;hD;CJ\aJ"49V^_ɇʇʈˈ & Fx Vgd4 & Fw Vgd4 VgdBs & Fv Vgd4 VgdZI & Fu Vgd4 VgdD;wMNo|VWx׌،{|}ƻƻrf[rf[S[Sh CJaJh h CJaJh h CJ\aJh h >*CJ\aJh h CJaJh hBsCJaJh hBsCJ\aJh hBs>*CJ\aJhBshBsCJaJh hBsCJaJhBsCJaJhBshBsCJ\aJhBshBs>*CJ\aJhBshBsCJaJhBshBsCJ\aJˈw MNo,BVWx Vgd & F{ Vgd4 & F{ Vgd4 & Fz Vgd4 VgdZI & Fy Vgd4 VgdBsx،4|}\А V8^8gd1H & F Vgd4 & F Vgd4 & F~ Vgd4 Vgd  VgdZI & F} Vgd4 & F| Vgd4[\ #&.tuɔGHmin*ڬ褍y褙褙褙kh h 5>*CJaJhBsCJaJh h 5CJaJh h >*CJ aJ h h CJaJh CJaJh h CJ]aJh CJ]aJh h 5CJ]aJh 6CJ]aJh h 6CJ]aJh h CJaJh1Hh 5CJaJ* ~ #ftu "7Gɔ & F Vgd4 & F Vgd4 Vgd $ Va$gd  VgdZI & F Vgd4 & F Vgd4ɔUGHmvX.ijklmn"^s & F Vgd4 & F Vgd4 & F Vgd4 Vgd & F Vgd4ޚ*Wx hڜWXc & F V`gd4 & F Vgd4 & F Vgd4 Vgd & F Vgd4 Vh^hgd * WXc|}/1Cqrˣ֤ͣפDEF]^_`abs٦vh h >*CJ aJ h h CJ aJ jh h1HCJUaJ"jh CJUaJmHnHujh CJUaJh h 6CJ]aJh h CJ\aJh h CJaJh h 5>*CJaJh CJaJh h CJaJ. '~ß"E|} & F Vgd4 & F Vgd4 & F Vgd4 & F Vgd4 Vgd  & F V`gd4ŠѠܠ /01C¡;Cbqr & F Vgd4 & F Vgd4 & F Vgd4 Vgd & F Vgd4 & F Vgd4ͣ_֤פȥ DEb٦u & F Vgd4 $ Va$gd & F Vgd4 & F Vgd4 & F Vgd4 Vgd ӨDEXYZulmĭǮȮٮ ˰̰ (.3>ºʺԫԟԗ}h7h7>*CJ aJ h1Hh75>*CJaJh1HCJaJh7h75CJaJh7h75h7h75CJ\aJh7h7CJaJh CJaJh7CJaJh7h76CJ]aJh7h7CJaJh h CJaJ1 GlӨEYZurlmĭǮȮٮ & F Vgd4 & F Vgd4 Vgd  Vgd7 & F Vgd4 & F Vgd4ٮe~ Flq˰̰ ±(O & F Vgd4 & F Vgd4 Vgd7 & F Vgd4 & F Vgd4 Vgd & F Vgd4Oeo~̲3{<t>͵# & F Vgd4 & F Vgd4 Vgd7 Vgd & F Vgd4 & F Vgd4#J0ǸFqºʺ#P & F Vgd4 $ Va$gd7 & F Vgd4 & F Vgd4 Vgd7 Vgd & F Vgd4PQ^CD[my5E[\p23I)Na߳߳ߨ߳߳ߨ߳ߨߨߨߨߨh7CJaJh7h7CJaJh7h75>*CJaJh[>5>*CJaJh1H5>*CJaJh1HCJaJh7CJaJh7h76CJ]aJh7h7CJaJ?@gKPQ^] & F Vgd4 & F Vgd4 & F Vgd4 & F Vgd4 Vgd7 & F Vgd4]Du[y & F Vgd4 & F Vgd4 & F Vgd4 Vh^hgd7 & F Vgd[> & F Vgd4 Vgd7 & F Vgd4 |E$]\p & F Vgd4 & F Vgd7 & F Vgd4 & F Vgd4 Vgd7 & F Vgd423I)% Vh^hgd[> & F Vgd4 & F Vgd4 & F Vgd4 Vgd7 & F Vgd4a$bx g|EFIv#'(~h.h:'h.CJaJhZhh6CJaJhHjhHUhZIh7CJaJh[>CJaJh7h76CJ]aJh7h7CJaJh7h[>CJaJh7CJaJh7h7CJaJ6B$$x qEFGH & F Vgd4 & F Vgd4 & F Vgd4 Vgd7 & F Vgd4HIvq#m|~ & F Vgd4 & F Vgd4 & F Vgd4 & F Vgd4 Vgd7^ & F `gd4$a$gd & F Vgd4 Vgd77Y|}~ Vgd7 & Fo Vgd1H|~hZIh7CJaJh\h1HhD;h1HCJaJ21h:pM/ =!8"8#8$8% Fs37rSx~JFIFC    $.' ",#(7),01444'9=82<.342C  2!!22222222222222222222222222222222222222222222222222" }!1AQa"q2#BR$3br %&'()*456789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz w!1AQaq"2B #3Rbr $4%&'()*56789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz ?( (((((((V4 &Q l"r `? sjċ+ͣiv\4nʊnj5[اMeHnd>FhT!eumo +-D-Iw31?/?uėWΨ$Yp( {FlzzfƧ&m\ѫѵ8y.{'Fvyc3`nvҪml,iK[ߴ]sIk7M.m"y}:;>ګpzQKM s6C)F@7P}`1\:~R@|M eapN;eD@dpEYŧI)V5\ j .4ⱻ$.gbv飕dWƆ>yA[&OO2.DU iWnjF涒ix}ReyAѳ9+Z%X|Al)?3í!uh;#hPPkKY.l^㵍8ħ;Hȏ<Ҵ߈ƛg*ެ>FFz+VW΋[R8#qr|[}*姂[GhK.?4EQEQEQIK@Q@Q@Q@Q@Q@Q@Q@ E-QE%-RPEˍi8^KxB~$i;$ZͻX^[6O2] z|H|?g-biSh7"&*}>JcȑF]Qn]?>էXkuǁw(XsT>&)o~!P?b~t RTF~eY(^YΣ5W3ѭ]r1w<\kM]ܣ_ip_PvyV )w .koe,yr2D[أ/,Nzh=vc~g~z5)GV .#Ѩ<_6*oȉn ]DR׌[Fm*R3n$ x 6=T]kC]u$*o v˸cSw^5|e\h,F Fɾ̌9R"}>]ӧOD܌( _GPo/H G$-!TѳvEz-T5K)l㸵vI€-R tE|DdEޙFgcMlx3ģ>nьveր::*yR(e5Ο~ Y|m/~v:*y}_߂Q QEQE`K6M"ȍqX<qjI_@uu9nb*#X#&M݂9c{Ұb[8}yFjw2[$kK{FIheml1*{;՟xe*Г[7 c_ Lf dAOxV[mCZAq 2F 4/I"Ng[.T{V˳lPuxUljm6mImeXjb.#*X+ѼŗLNO;*( ( ( ( ( ( ( ( ( k2fM:_5?x+x`yk,1/#z>?4Llf{<+EA*zxnߙnu޳P-(66wsnOwtj Z.]=.+Yռ%<8cd#*a=+5RHߐj leHJ,,-4lXm]ƽ _x;wiK|,WzyO~'jziZZlEտxCMt1]1wۘŶ>rv~=E?WuZ[e#qqF~Xj ˅ zeA@n~%C= 7Ln kG08L>7VVIKZilO.J+ F*ٯut>>/t;@,Ωq W6YMp̫wL|F(_1Qi~|pR3a;|}_VbwczL,_ |*(nQq…|2=mN5I+'"e@4 1l|ݨ]ZC?,~b*aчMU='NM'HӢYR^V0QW7(m@ RU+ȥ<(+5 .7Vm OuXe-||GëoP}Zgl!s?|亼/坏;A?(޼xXէ'xi @ǯu1/4Y?S'_:74 E?8#zGu ksǾVKj>">鵑/i(ѧҵ8|y:2P'|WpDԟ6'^@TԯO/w-/1[.m㼴Uєq?᥃ E ]mEܢ/< J+uPk~j2TmAc$__C^@ Wa㶏nXư(I?; cSO]oTan,'!>,4MJagw-P@0+ï{+, %M\ܙpHsM _ -**w/[#oZд6Zܰj8žhd9I^(5sM&mmWsP)[Òְ>^+?'lOhպnjzc`l'x5Icq?<+Ʒk$t>zֹu e~M 5L&bٵKYGI}߮G^Ey$㏆KneW`eղpXTt2׶:7wT[{c9i#'o< F" >%R.[XdXUX!nC`]%YO÷:̱#uA+1 S,|m]\csᛰ0o_+ˬ'ZJ(((kƾNktak᷊n7"ɸ-,Ͻzy ǚGoSA +';][O}n{O u̺~i 8x=kU?/bkF| #P=;TkeӯmnC qUeE,̀9$Ͽ<sC@g}1jT7?şix+=A/eֱKkol}_|RI4hk-*3鸎1LhZ<<'@̷b{{Z%#qǻsKw4{/TYf\2e=hB9XѕцA^A%y NÞ'e6W|=v\(( _anȉϴgc}Iլ!<ƎxXÂ0vs]ri,PNJUfU#_Г[2/٭q;B"8;oS@<;fMF!h$J,p=_b緽ij$4[kkۃ,`F9` jڤJk'l kV!y}KOtԒ KfG0.I2Aߖ<1G=[>ҥۂG\JoG"M ۹o^nt]}==.IwR Ce@4QEQEQE?|Cqr- K &IH>C÷\d #@K1;הx_u?\6dH ;|' fF=q,߉ݢwA5zXʼ?+nMy9k? |vi^>=+M}OW\[XCz3>i~ ~dŽg\fgZ>(JX>OkW2$챎z ;aG$*(U\r%4o.E'ƿ X~/[I66jÏ#Mw U+Ŕ]|5מuh rchڭꖇ0]B&z*MGSlQ?,ξyŁ ~M>m1{a*ﴟ:"޽m16-M8D[4A=%U3*^TᧈDz-?u5ڑơUG5 Z=ޒ>os0.bqd ͗{q{ޔOZRWkvU;%2$,$R{^yX̳1.NY8+u?@&u;%3 ;OTI=&o'T6s_F'<ܹQ³pwUM5Mwm<MN?Տ5VFs^ȱ[G=}>o:TZL×ۥzMMuo}o |s1{W!Cz|Gif Y [3W~ߢuD}!7B1xJNV+ݠ>~ukƚ!gүUO|hZM~o &(nwCQ=o Ÿ5 \m;-02K E;OςI8P\,}l.~L=DPZ^Vel;fqi7j9#IbduWF!%Zd䭏X |W3 m 6??tx ^ƞfo?<sEPW[Qi;o)7S}WxS]Úm$>\7*k/n-NK-ՁAv=:( i6{Ƕ'܁Q1W[\Eum -):PFEbDzƔ,gz?X~m#~M3( >xgyd>UcӡzWx6YuPIuE iqsɢضo1[~FKiZnyTt 5B[J..}Z畵ݟ:{ xH2GgҜV?3.|K߈|ie$n /_2VWVu+UAt"QQ`@;xᮉy?M e6Jq--F1cծo>vOB+Hz#`g?㡠 :B~|Pd;C[ڠu%?uֽ~Q_rG_&q*߁ u`ˑҝ^w7~]cB΍Ԡ+(6_ɬ!\wYĝ-5hz: PT o ' h6t:o)}WRE? B6χFHoE(+իɮ蟴}*îi< Z( ( RwQdܛiYWtK$lJk(7 :=ҭ%b!7 #hڦl ?+`(h!$Tu~Fnonր5| ^.u1m;hϲm{Wh DH1 jye5gTuMS\w5Rm72،f keޚs(>[JűB~"OiG-YPRFvv𯅭u]]@ymc<5k}>]=&5 Lk?LC9Ojq7u?v?~iQkzmp@^7mw(ueO69DCz]>+FރqmF,%~6Kg<w$_WSvDN F/"9Z9񷇴i^4ίkw{5Yq?J"-ǵY^ ,&^cxߡ7ޅf S[ ,e`d}oz(HDT¥؟_<{7Ok[yQ 7Nºk742kmQ5 ׄ;HK5ԼO%m%rq5?dh@ x(գCjeFemh3o W~j2_jw6.$滑Jr"E?~TOyqx3đ3I{!v-Wn؟_ʚDcC7r˯xԿi{67C_QVo ^'W$ӗNj%{:#^G<ʋyݠ&.-oKV?kxKOɿº*-|鶏*?r?| Ekt_7m?I]-;hq|;}|?k|WBQ݂S-mݠ~Ŋ:ſm[L&nʫx"G4O.A&ۀnA#ڽh?@w-_o)Z4~uK edŬWx_R,+Ҁ+O:^SS[ⷃWYFzV;k}i5NjfYn2+r>}7➟Imn uXH(ẉ'./Yk7zYgY-ؔ}~0<-k%O~W ;^u-mapl42nub^k}pG@B0>D\y>B˪?5 OR}ۻR~)X.Dڋx)dth#Bekt$43u{UQEQEQEqgh,Zg-Law 2+h_kg=E1SK0tt2O3(8e Y(z+𶫩7:ķmj-8!՘a]=QEQEyfM\%a ~j+ͼ9cozOH->MZ0HOtj~'ma`d^+8Y|A W*Ś[-m-3Yu zakZI?Vir`RުI>oZX,cWLv5//X~_'HΒ]v uN0hOB%ų鶓ƃz5ԣ;}Ѵ7-h^? }$ XO$_g.4Y7uK=duhmm. dD<o5 Zd~wuV>qh͟tm0#\7K \tA s5̣}3]^vg=#S}M=@ Ьj(%NlXcmū^jMSUQ6@'S؞V՜M{+1] _mf1她㷽$wQE6\K-׹Qi 1@ Ou?EAY.eVwEuHP:$rY5]z;J9 M Nu[Po$y'yΙ-倖$fب%lCPPs #iwP!6*P5M!iuK$i-vr/ {FGӭVPPeX^e;ccQqsKz){.s,$UҀ:M4(渆{ՊKhmѾU _kr?5jizew!FVSVVpw u;Bkb7[Xtۑ\G~ݪc-?owLkXOMoQEQEQEQEQEeۻʍ=~,j6 ="NS.lb03+/-cqno&LW|+MGN<^rry7u?tʷR4q@C+mS >lsP9>k#2 qvl/>j4rXjְʍpً.YR# Ǒn[?{=i 㽒i5H _hY"A(NG8#Pb̰Hř*~pJ0r>Z?x~YbM@1OI8i~:pk{aKݐ")e|o^vQcjz]|H/ʹngHu0xwhQW42)Ǘ^]</,p^hU(H8_x32guk{$ ,jlͷ\wVgjuńZIos;,m` QJlFxq@^$ӮW]7x_-+.rx\%|z㷐,[Yػ+sK~j*Q pEo7Z< +G.v8|#uzE/t_lWRyJTqڷt}j]k Yd1> CxoWYjE8]؆_3#p#q]G!Y~}-ڸ/ۢ(((VVѬwPG2$*NU Z3tˍNNk$vpт=PM +i'S4q4 kboiogy~l,cjPEPEh8լ3Fq@ -.Kqv,(pd{w'^:c:fO[&H̷^ do*N<۹:v_kj,ms)G]8چ/xCPgSOAu%Öwb~g˟O€8oFQoy%b~ h藗 kps+F0?}ǽq%.66'Exzh4xKC&?q'n|>K> a4U sm%jC >؁-``uD!;x\Ή:߰jU]oR_'K@#v(^J\xW]gzqzӡ.Y.:1IO%PnfqRAYI[Ӧ]kϩg+#1@x6ž?圃-t5=`x/ǧGx/t wΡ!#rM?(((((((((((Xg*ye'Ծ\Hu+kUO7nW(((((O>ZfF&=WN_e}~W3 [urng6 /4`Vֲm."B%q D"3oڬp Q\ty"Se; GFnJۢ< ݾ1J^~hWTGYXxv n4X ׬WOXxAa$k9w>@Wn./k<dǑ iy)g;IqQ[mrrҬ=݌O͵1j#⻹{k+eŔ8,W[{?ҩZ'N湞axWOpiq@SC.!k[! _²m)]CM[Ku"$\Hd.:v5ZX'5&߱Oma9:j$>|9ò1XqP$,i<&&]#($$d'K<1Vk[K!~~SpF£?LAx/EI,[UӟJMYv9Tѥ'Q𕎱[tڨXbJ W[\ݛ;ϱ{xbxbLDg׊:ULj#{$~22Ww'OSO.F*\k9is:n?۝XA@s^עo씿xsNo>m9]eɷHw7/I_8 @_Ċoj~mQlj0;7cl?J먠G|żwVEM=x@ŠS¾!_Qz[cEӛ>!ڪ!n ( Կ!oZ?d1uPi>ǥY]Mk#^5UZ8~l/)XC6}[2(EgykWwƶ[ Ζlò;cڀ.Z6gP*1[b2n̑շ o'm':z[Eu[ Pd!~Wmuma+sjUHgBg;sIi^.'yl#xmXLEM1rHn OjZ]ăNKxd#,T)-_ ~O h`n(3qzfM\D_&[0MK˪\k6wړyZ^GQo4eʸ[ZG.zI±~UFr0-ݟ f;b8\! PAAʹ'?U 2kۉp@ͼ\K]C@{5 *kZFzϐҹ_K5gnhΰ^ͬ\nyouP<,gu3M%M'@ Dž4IsI>-miZ{y6wO/a'ݗGˑM\q.FdȒb H5ΊU"Ηlװk 6vgѴL!٧B]n?,Wm>֖ZI~x6&[5ڷj۶]E|ż't35MCZIoHh|x[r}KuOڴalt3^_?𡏯J]en^/%Z[s+^"ۥ@:gֵ$P_M3Z-u{ȳ s"ǐy_|'y;[jMu]x0˟Hpf-=kz&gkU5?_Uk>WFԴ=ćWiƛm_߂@׃{sq#A'ӯ=kkDG?PYx+xݹf4h$@B^5~:eK&^i3bû8z& xhҵ;Oߥt4QEQEQEQEQEQEQEQEQEQEQEQEQE.\}6UW;k1^ jQ@7GP4|УZUwF\tw5aOy`XT#xz:-/Sہ v:>K&A\|vрU@ZxwFQ|@ @dÒZ7X_Ih>L!qo"5LJGDuŠ2H|g-$qo]x+]kk{y,k% t̙Cw 7_ɿWҴH ;xx)U#U«{s7Z}֐m1A$`m\/l+ ռ7RY/-$lwo#VmVwMn%ӣK eWlO~3F vhve 'ϗhE pDD"U^-SYbxiՍDi^/cȳ)@?fulCj1>\X"[E]&>G޹5)ZI5m*v-;tfΌz^|#[3R'Sh6Ţ^[[1xCMҘuwm9?K4,o>)R-b|7LK9ԞP[,o>]yF|H"*'֚ˁs2]L?q?ƣhZ]p|KǶ.>핷sh)mUVtZ/ٴM?b$u f P>&?we8"{`~4>Qa^ji!{3/xVvnyoWGDk}h׵<^|}ƹoۭ`DbMv|1|hݮjiP G}F|gSv8鬢m4{k= Ig87O=R4R%:^ܯ .`wvMkW+嚜rEI _EhgB~ܦ-!ٷ-?4,bMW&Io}J?#Jm c,ol1kC4scێ+tM7G061l7BzZ@qǧ4V6oCrrǻ.dm?ti~)Ju]<,oB$o9p@۝b d,h`SgKcT7p+ġFf0zn.P[+5 "Z`6;ng^x;^uxnڣȰq#]&>q.8.RZGfs^s>o6sz􋔸-> Zï5iius"`(tWxcC ˨ !rMb!һ?xᾫ5/yİ&,1(o^:O y f d~}IuXCA',H2iOk3SY&Oȿ.Z\7r[X9e9>+O:_ bn55YZ`l⣓/[JM&Xlt4qʟi>?l^Ex_Z[iښ :e9{婗 _u^_x~"KUЈs^Ex.eΫ6/L~\+ZH@= 1~V9 4\rv*h|GҕE($-4O6OhH>}?*+?=~?NX!>#ȟ៽<'}?[[ O[Eqv-iG]ǡ$Q@["v:GNMo?^"^\|# ~!8t }W7VڕWq,c6x""?aaINzs4B ?ǐYEm ?`1O'z|r ({mu?ӤSxxISO?ZI۟ig%i>59.Qa5g4׸ q]mQEQEڏnյ{ؒ&3Iܢ 9^v%Fo+M>LhYI%vX4[Tӧ<(Dʫ4dʾjGAr]HUe\K%A>:`P.[X`hEܒFPEO@Q@Q@Q@Q@Q@Q@ KEQEQEQEQEQEQEQEQEQEQEQEſíK&fiM򤭷ލz)|; Hd(HLh$]> ӵjT%cY"M:'9` t,O6Uts+("L7[,Jg/y?/8Ҭ>n,|;dNAk34M@bm^W&vV9?V:(xyb,!Ivr(e`{h7Ŀ cM77Ni $ּO?;Ե~| ndrzB<'Bƍ8~ccHyGYzG]gE@[[)mWP'_Il#l>nUnI&.{ߍzK|1rxAo!Դ{k]'V[i? ʬLI>M $u 2>*ma>;ҽ_ ЯM3V?? s}K ?5h4oL7k:1Wu0:f= tWkhu{-Mpsz >WF(X>S并Aťon*-s5X闟%Υ2]j; fT\Y(Dn>o^{4#;Or+״/ TM>l|^ μg_.nn5}/G\7.gc_Ӣ/v}¦-Է$eb\,+,t ћ;uk)5IX\w$š[G3ɕ0=[7t&{/;/>ġnAKϯ">ѺkXJ79<7|.T^vwDm:fW [G(€4m6iOaO2Q4@!-N14 Ak OmwHUڭ__/b2Q;_ |LhӔMhCa_кwV?YCmhwR//&//tV6:үtVIO@|BQ4-mc Eu![kj @!-|Уh+h@0])4HtO'6/_ۖQ4nѿ ? H0Ng)4Euӿ)?Ƴ[I"GW[Fc *ghsxH _TC08oH(4𗆣җe@7(H⩿xOr$A.pY_v`x$M=|9V] 'nOpPEVUbG`e(,zj&ϬYuk8oQ:;|OakkY]]D0-M=(乆#Iff\8_Z^#z_wwGY6qVGuIm/?oݵaAioV=C1v=~)⹏|2,r7#dppzTzֿ.n/p+tep ؂n3o$Իei:?QEQEQEQESYf8<'ŝ+Nm-e(i}e(ujoȺy|jЏ7/[Vr@?^M߂-WU{&] }NsZ!Ř-~qNH&1f5?$o#'0isǁW4{ KF<)"cr-!ڴcK~g`/i?_Z|Wk&3n_΀Ӭ՞m]{b_fn3ޢ*q>FU[gcϩ? b 9->?}p=o.sy MGji^%@-4aOޚzs]~0j4mR [nFw8֡U/ݺZbHQ=CX~VyhдZp Ĝgj=;R"csW>xfRy۬@;`vlfG ЬPJ-5|sO ((((((((((((((*0AK4q70Ҁ'6TE6Yb&Y#^K3`ƀ%b1|nٻz$(XDPAn[-1+qO_rO oK#Omcsv~Kh͕66qjWf#j!S_IZ][j^Zʓ[́9EOv>J4/ ^zit)%WZ#u&x~95ih0־ҕ⷏*7ף1,KYS^v>pTЀGӁQxH]N{-^X.qqNq{?`_FOFJF,w\hv/\a5mH `ғO^e5;球w־ m P̍ tVH]3J,G6˳spGʧdՓ^F]ZxD֒Drg#2?}%?GhW~-Zծ+amQdHӇ]Ӳ1XڄS Kѱ׮hU"6yiՠts{kzMc1\HPórJҽsbu*6'WWkoOUZ?<|Ek]vTmݠ=~*x!b_G VuQv9Z^o-k?Er GM|Anho U 5mݣh# K@~>M|C=mݣbu*G/1U_[1=,RW 5iv붝v9?Y ⢴<T_h.@-go$6<Aot_hGhl+_TյmSZQko[f!떱5+;TԼoc1˸B/΋tU~궩5-41[?M¯izi6+}]Oo/Ixu#׷zGGjwbҴ[mm/9#uR]ʺ i3E#0?ʸi"",~W6wc-ooEcex+mA'Y H;-as޷<aGK g.l{ZݟZ?yնYGBL((((((((((((((((((((.הGU]Yv.n33'*xz 5H-Fͻ?%&}O"%uD;نP!O*S(upi[n˺1L%&8a$Z o,-f2ś{I@%EuPEPT5;T ky&|M_9hUtaF\|X~7t)M`u+N6g(vt3F4[ Hܖb0{V^[?&}_ @Cqh$:T:|@7j޿,'\բRmGӶ;/ _`הM9|+WA=qi@//c\t[S]n%iGByT΢:턨sy ^E38lu'í KKojV3%eaYm7Wëoť t|rDUsǰ4 X/M6ˋ-B@ZH$cm/-5bJp&I:ud_Ӿ h]etR3.^?gHyG=|i&,natpWxv-wKxpj6W[v iw_(j#kot MZ?2?_x}wM?q ݻwyGN3-q14c}zo4x{_}5[ бqN1wӗUھ0??&,Q鞿W^n?*+»5dtA/0|9sNQ4o4 y[i״qG;G zGq$jO4Ü}>*?-q ]|7|?УixaWo#FNQ4 ?* _`ҿ.?*}'ܣj?B+Bޑ14 s-'Txo* mUoHAvK_/i_@Ì̫ (}?*K7CTC|.[qޑC.i?@ oW?G%Jkx; [ÚAQ}>o!^۷#@U}?llUB{:A9Gоƍ141WoTih~Tm _ MgoS7/&,UgK~GQ _s+#⪺#k|1sN14=ۿѿ/&&0iCxkvq.?*oUoHo cFOn? )޻PxQ_\4&%YwTOݯY /׋j? SkVӴZ f hl@nv3@fYX䂣ӥlg :G'մU /a|=t{O X Hg,ϥH &)ˢi+t%@@o31O*l?|<Y".]>@?Nm[^cc QEQEQUV@02mr$C@y=Wq>-Q@Q@Q@Q@ywz!^ԥ}>IxƓhCVo-ۀI9EEWZ淩IɡiwA雏h;¾-^!&&Y1i0Ip7\溵XYꚆ!; z.O\.gL(@ZD++Ur1Ӽkύd o=N;/jmMiZޝ{iI WfXq.WϰһHo|Z\jO۫-;8Ӡ\t,?3 W;]gT .9mXj wkv^=Z[麎~XlouD`w=ފk(ƳN-7~O9>v9t-sL1$B{`wp?zu6|Ak۲08ZߦK.)Ҁ-QEQEQEQEQEQEQEQEQEQEQEQEQEQEQEW3c]6Y"hڢao/v=}I@-ugTկ[Hi׍]ONxO&jWꚋ&~ =MzO|E&IyȈ4%x6e6B >`3ᆵ}ڙ8WK 4H,ANQ@ EPQK*CK+"fR3/,:Ѓ@/jWՄQR &Wk,{tXjyP@uC~_xc#GGp|9MxΝYh]6I~5'eTԹʋ%`OM*ki!teOW->|9m]l3e,h@A W<# Ki4 .Iw{HسԒI^MyzV>\ͯOwO)c5%ֳg0_inhh^?z!#zG=cj6?t M|St 5-Bpvh8I6_jw^wmm`'~5^ѵyn-:XG(F\ б _My-GewhڤZeb> ԥWy_l5]53J%c?4˯IZK9=[a#??&|Ya.a%c.x~MFLGҮ W"['3ߟj. @k7Nm7][ ?7+؇",i114@|cGb(d,.4fr|3]O\g`iU5K{ W]Q$X48 o,S@Ӗ奅mFFT89[H8€W7^nfI&GfcԒErVR|:tK[dOZϏ~ .'c?03M='GGW cHH€&ӼiVZ턑gi-0C5{ 6^guǾд뇋Z3=HQh 28 L/#/&-CfckxCUΜMT?7S7/&^ݩ͠id4xH yh`RB4_w$Z'tAο I\\Xʒqop7|u +_ g15OO]м3Yiv}e^2 >\n#x+{PQkkMFtu]'F<.^qO31h蛈=+_hݓ(,ApGƛ 4i_Z:Fdm2y}/O:WӭHV)h<8ԟ KZ:tHYXV6@?JN*i9 q@h(((((((]V+"IV 09U-75cNQoOе 4IK3ٽJOem; {m=3c4f)(q.7%me733&a W#2] Ӽ6i1 KFB7ׁ]]ekZf :y@ꬹ@i7R-/Uq<+(h6F~R@8*fhDz4iR;p[hkN1O&OR%bnO֩.o7G pB$j =+GDz$hȼ1m_X\=]Ouu%G*`z%-B{vNk;${%&;7̹/OIy{-܏z+b ItAډDnwPޮ<_o9. y D1&~uŠ(0O j ;ɒᶰ_28ϙy\|''3-MHH܍bAFqF]e뺊i:Ն$ds _Fg~nwxbW).lo>\E.6s]q [Q]v^mb?vx['ۡK3 8M~JL<3oXGsnH xDENC)}ʯduۊr|Y.K?+odfݜ@QEQE`]o xjUXV@S/",{&A-CM4A%>`o6vFa]=]OH77Y6 #OgpD>͏9g PEQEQEQEQEQEQEQEQEQMfTRǀ95BYuFT)pmąo dYU0uuXP7q{ |e5-J$@Ǵ3]nZYg-<Λ}9 Z( +0H idĻXx`O:-gMWVwEPEPEPEPEPEPEQEQEQEQEW =f}^'}s{ѭsb}'Vt;{6yr>rx h+ i:N_Oˋˑ7mRǖ'Y0n~&4w?߉0n~&4w?߉lx{WKx`5U6.HP;1 *8VlmV z+Mo㏎t;.kwgT:UqRr᣼a@Mh+h7C?᣼a@Mh+h7C?᣼a@Mh雐Z` Ѽ;id?lTr$ !cg; vh7C.Gt'FYdEeFWO7iΕj&2 on[1[.%۞6+U/ N$R)WGeSrU4 `Z=bRNu}&$; l_G\nqZRZj2jE$jg!-G<'vxuy4w?߉0n~&G^izٍOOw] H$ͤ隹mkU43<yGP}S/<ót; vh7C:Moβv[}`x8ٜ^_0Gx o;@O_0Gx o;@O_0Gx o;@O_0Gx o;@Oב^Xjg:ǫ:FU1c7WGx o;@4qx=UWKY7 raJ:>v>:d6,Qv<2m+⼊OM ya$m)d$`>gzT0n~&w>t[ squxb :͠eZ.\Y߫HŦ¤{k?᣼a@Mht?7KZ 6:8jS'xL[wۻںim|L\D̳s4N@?Q#\O4w?߉0n~&9;dՊUDHmw#o󵸘8<j7ŏ6Ʃ oF |Bϟy@@Q_0GxՋ? "$yR$h9^ʬ}4E>uI㑢`皯 o;@O_0Gx o;@O_0Gx o;@O_8Z|s}:}_.A83dp;4w?߉}?E| o;G4w?߉}?E| o;G4w?߉}?E| o;G4w?߉}?E| o;Eg?vm%#QmV[Ջf;H8N3Iw_].4^{bVafKdBAܣ.L!z#?4hӿo?ϡVe#m,u)+(&nĘGt!AQl@ h6W/X˺S"K7Ia?N}ƏM;}>OkĞ9чGխ5D2byI0 {m-]~6$|ajmOĖp"ڈXaSҼcN}ƏM;}>OkaG&>]هh~*:ȶ5tI883,hE$ mRvؚw4bi}XN}ƏM;}>Ok}biϿ>Giab?{#M;}?4h>?լ_GqWaϿ>G&>]هh>?4hӿo0V]&>ؚw4}vf/8+ӿoN}ƏZ4~GEvؚw4bi}XN}ƏM;}>Ok}biϿ>Giab?{#M;}?4h>?լ_GqWaϿ>G&>]هh>?4hӿo0V]&>ؚw4}vf/;Mo6i b9AhخqZ4>$xŲE-ʬUP J7Iؚw4bi}XZG-]S̵-Gtli_(mnx3??!v6gF:%L>q;M;}?4h>?լ_Gw+ÉkO,wI^ϧikaXi~\?1 c%4vң qZdӜi$%d;S˕A85ؚw4bi}XY'#ho+O3nGضgf/yv8oY>HҮuRmOYZ-R,q+J󌁃oN}ƏM;}>Ok?ş ]kRƽ$\i" 7:wT^Pcq^<e݌Pt֗2H{gTĂc@{Ͽ>G&>]هhDվ!n{uJ}7Di xјXOʯ7(Ծ x^Ħu$GR")bh@q!ۙ~n;rk4hӿo0VZg'ƶq7*@JHZZG-]S̵-Gtli_(mnx3ؚw4bi}X> xD<=Ziwv&arZA︂ dʶ=ګ>to+OOlv`|Erؚw4bi}X􋟈}Fn6ͦig%)S9Wd(el5&/z\kR]$Z,3C3+J*|B13ӿoN}ƏZ4~GEvؚw4Q}XDyK http://www.theraderm.com/yK 4http://www.theraderm.com/DdcD  3 @@"?@@@ NormalCJ_HaJmH sH tH DA@D Default Paragraph FontRi@R  Table Normal4 l4a (k@(No List4@4 Header  !4 @4 Footer  !6U@6 ZI Hyperlink >*B*ph n#&N$9Ocu 4Z[e*\=>O:  ] ^ ( ) 7 B I)3BGQ\hi  T@A@~CDOPV0 #d/0!QRcDLu  6FUfx K L Y !!L!M!!!!"""N#s######Z$$%}%%&&&'''''(f(())^))))@****$+d+++,S,z,,,,S-'.(.Q...//j////001'1(1<1111422223>3m3333334443444u5v555:6}66m7n77`888Q9R999::y;z;;<<==i==&>'>2>k>>??&?h???@"@#@-@@@@#AlAAAAAABBiBrBBBCC ClCCCCCCCCD DfDDDD2E3EAEaE{EEEEE&FFFF-GxGGGGGGH0H1H8HHHHH=I>ISIIIJ JVJJJJKCKnKKK"L#L8LLLLL6MMMM>NNNNNNfOOOOOPpPPPPPPP QQ,Q4QFQQQQZRRRCSSSTT U:UUnVoVVNWnWWWWWW0XXXX^YYY%ZZf[[\%\\]]\]]]]N^^__\___<`=``:a;aPaaaaaabbccccccddddee+e3eͭ#J0ǰFq²ʲ#P@gKPQ^]ոָDu߹[yƻ |ӼԼܼEŽ$Ӿ]ݿ\p23I)%B$$x qEFGHIvq#m|~^7Y|}0000 0 0 0 0 0000 000 0 0 0 0 0 0 000 0 00 0 0 0 000 0 0 00 0 000 0 0 0 0 000 0 0 00 0 0 00 0 0 0 00 000 0 07  07  07 0 0 00 0 0 0 0 0 00 0 0 0 0 0 0 000 0 0 0 0 0 000 0 00 0 00 0 0 0 00 0 0 00 0 0 000 0 0 0 00 0 0 00 0 0 0 0 00000 0 0 0 0 000 0 000 0 0 0 0 0D 0D 0D 0 000 0 0000 0 0 0 0 00 0 00 0 0 0 0 0 00 0 00 000 0 00! 0! 0 ! 0 ! 0 0" 000# 0# 00$ 0$ 0$ 0$ 0$ 000% 0% 0% 0% 0& 0& 0' 00( 0( 000) 0) 0) 00* 0* 000+ 0+ 000, 0, 0, 00- 0- 0- 0- 0- 00. 0. 00/ 0/ 0/ 0000 00 0001 01 01 01 002 02 0(1003 03 004 04 024 024 024 0205 05 035 035 035 03006 06 06 0000000007 07 07 07 07 008 08 08 009 00: 0: 00; 00< 0< 0< 000= 0= 0= 000> 0> 0> 0> 0?> 0?00? 0? 00@ 0@ 0@ 00A 0A 0AA 0AA 0AA 0A 0B000000B 0B 0B 0lCB 0lCB 0lCB 0lCB 0lC000C 0C 0C 0C 0C 000D 0D 0D 000E 0E 0E 00F 0F 0F 0F 0F 0000G 0G 000H 0H 000000J 00K 0K 0K 0K 000L 0M 0M 0M 0CKM 0CKM 0CK00I 0I 000N 0N 0N 0N 0N 0N 000O 0O 0O 0O 0000P 0P 0P 0P 000Q 0Q 0Q 0Q 0Q 0Q 0Q 0000R 0R 00S 0S 0S 0S 00T 0T 0T 0T 00U 0U 0U 0U 0NWU 0NWU 0NW0V 0V 0V 000W 0W 0W 0W 0X 0X 0Y 0Y 00Y 0Y 000000Z 0Z 0Z 00[ 0[ 0[ 0[ 00\ 0\ 000] 0^ 0^ 0^ 000_ 0_ 0_ 00000` 0` 0` 0` 000a 0a 0a 0a 0a 0a 0a 0a 0a 000b 0b 0b 0b 000c 0c 0c 000d 0d 0d 0d 000e 0e 0e 0e 0e 000f 0f 0f 0f 00g 0g 0g 000h 0h 0h 000i 0i 0i 0i 0000000j 0j 0j 0j 000k 0k 0k 0k 000l 0l 000m 0m 0m 0m 0000@0n 0n 0@00o 0o 0o 0o 00000p 0p 0p 000q 0q 0q 0q 0q 000r 00s 000t 0t 0000u 0u 0u 0000v 0v 0v 000w 0w 0w 0w 000x 000y 0y 0y 0y 000z 0z 0z 0z 000{ 0{ 0{ 0{ 000| 0} 0} 000~ 000 0 0 0 0 0 0 0 0 000 0 0  0 000 0 0 000 0 0 0 0 0 000 0 0 000 0 0 00 0 0 0 0000000 0 0 0 00 0 0 0 000 0 0 0 0 0 00 0 0 000 0 0 000 0 0 00 0 0 0 0 0 0 0 000 0 0 0 0 0 0ј 0ј 0 0000 0 0 0 0; 0;00 0 000 000 0 0 000 0 0 0 00000 0 0 0 0 0 0 0 0000000 0 0 0 000 0 0 000 0 0 00 0 0 0 0 0 000 0 0 0000 0 0( 0( 0( 0( 0( 0( 0( 0 0 000 0 0 0 0 0 000 0 0 0 0 000 0 0 0 000 0 0 0000 0 0 0 0 0 0000 0 0 000 0 0 0 000 000 0 0 0 000 0 0 00 000 0 0 0 0 00 0 0 0 000 0 000 0 0 0 0 0 00 000 0 000 000 0 0 00000 0 0 0 000 0 0 0 000000 0 000 0 0 000 0 000000 0 0 0 000 0 0 000 0 0 0 0 000 0 000 0 0 0 0 00@0I00@0I00@0I00@0I00@0@0I00$, 0 0 000o 0@o 0@o 0@o 00I00#&N$9Ocu 4Ze*\=>O:  ] ^ ( ) 7 B I)3BGQ\hi T@@~DOPV0 #d/!QRcDLu  6FUfx K L Y !!L!M!!!!""N#s######Z$$%}%%&&&'''''(f(())^))))@****$+d++,S,z,,,,S-'.(.Q...//j////001'1(1<111142223>3m33333443444u555}6m7n77`888Q9R999::y;z;;<<==i==&>'>2>k>>?h???@"@-@@@@#AlAAAAABBiBrBBC ClCCCCCCCCD DfDDDD2E3EAEaE{EEEEE&FFFF-GxGGGGH0H1H8HHHHH=I>ISIIIJ JVJJJJKCKnKKK"L#L8LLLL6MMMM>NNNNNNfOOOOPpPPPPPP QQ,Q4QFQQQQZRRRCSSSTT U:UUnVVNWnWWWWWW0XXXX^YYY%ZZ[%\\]\]]]N^^_\___<`=``:aPaaaaaabbccccccdddde+e3eͭ#J0ǰFq²ʲ#P@gKPQ^]ոָDu߹[yƻ |ӼԼܼEŽ$Ӿ]ݿ\p23I)%B$$x qEIvq#m|~^7Y|K0T1K00@0@0@0@0@0@0@0@0@0@0@0@0@0@0@0@0@0@0K0j1@0@0@0@0@0@0K0p1@0@0@0@0K0u1@0@0K0x1@0@0@0@0@0@0K01@0@0@0@0@0@0@0@0@0@0@0@0K01@0K01@0@0@0@0@0@0@0K01@0@0@0@0@0@0@0@0@0@0@0@0K01@0@0@0@0@0@0@0K01@0@0K01@0@0@0@0@0K01@0@0@0@0@0@0@0K01@0@0@0@0@0@0@0@0@0@0@0@0K01@0@0@0@0@0@0@0K01@0@0@0K01@0@0@0@0@0@0@0@0@0@0K01@0@0@0@0@0@0@0@0K01@0@0@0@0@0@0@0K01@0@0@0K01@0K01@0@0@0@0@0@0@0K02@0K02@0@0@0@0@0@0@0@0K02@0@0@0@0K02@0K02K02@0@0@0K0 2@0@0@0@0K0%2@0@0K0(2@0@0@0K0,2@0@0@0@0@0@0@0@0@0K062@0@0K092:H@0@0@0K0=2@0@0@0K0A2@0@0@0@0@0K0G2@0@0K0J2@0@0@0@0@0@0@0@0@0@0@0@0K0X2@0@0@0@0@0@0@0@0K0a2@0@0@0@0@0K0g2hM@0@0@0K0k2@0K0m2@0K0o2K0o2@0K0r2s O@0@0@0K0v2@0@0@0@0@0@0@0@0@0@0@0@0K02Q@0@0@0@0@0@0@0@0@0K02K00@0@0@0@0@0@0@0@0@0K02@0@0@0@0@0@0@0K02@0@0@0@0K02@0@0@0K02@0@0@0@0@0@0@0@0@0K02@0@0@0K02@0@0K02@0@0K02Y@0@0@0@0K02@0@0@0@0@0@0@0K02GZ@0@0K02@0@0@0@0@0@0@0K02@0@0@0@0@0K02@0@0@0@0K02@0@0@0@0@0@0@0@0 @0 @0K00@0@0K02@0@0@0@0K02@0@0@0@0@0@0@0@0@0@0K02`@0@0@0K03@0@0@0@0K0 3@0K00(-K00(K00(K00(@0K00(@0(@0(@0(@0(@0(@0(@0(@0(K03@0(@0(@0(@0(@0(@0(@0(K0 3@0(@0(@0(@0(K0!3K00(K0#3@0(@0(@0(@0(@0(@0(@0(@0(@0(@0(@0(@0(@0(@0(@0(K033@0(@0(@0(@0(K093@0(@0(@0(@0(K0>3@0(@0(@0(@0(@0(K0D3@0(@0(@0(@0(@0(@0(K0K3@0(@0(@0(@0(@0(K0Q3Rm@0(@0(@0(K0U3@0(@0(@0(@0(K0Z3@0(@0(@0(@0(@0(K0`3@0(@0(@0(@0(K0f3@0(@0(@0(@0(@0(K0l3@0(@0(@0(K0p3@0(@0(@0(@0(@0(@0(@0(@0(K0y3@0(@0(K0|3@0(@0(@0(@0(@0(K03@0(@0(@0(@0(@0(@0(@0(@0(@0(@0(@0(@0(@0(@0(@0(K03@0(@0(@0(@0(@0(@0(@0(@0(K03@0(@0(@0(@0(@0(K03K00@0@0@0@0K03@0@0K03@0@0@0@0@008@0@0@0@0@0K03@0@0@0@0@008@0@0@0@0K03@0@008K00@0@0@0@0@0@0@0@0@0@0@008@0@0@0@0@0K03@0@0@0@0@0@0@0K03@0@0@0@0K03@0@0@0@0@0@0@0@0K03@0@0@0@0@0@0@0@0@0K03@0@0@0@0@0@0@0K04@0@0@0@0@0@0@0K0 4@0@0@0@0@0@0@0@0@0@0@0@0K04@0@0@0@0@0@0@0@0@0@0K0#4@0@0@0@0@0@0K0*4@0@0@0K0.4@0@0K014@0@0@0@0K064@0@0@0@0@008K0=4@0K00@0@0@0@0@0@0@0@0K0K4@0K00K0M4@0@0@0@0@0K0S4@0@0@0@0K0X4@0@0@0@0@0@0@0@0@0@0K0c4@0@0@0@0K0h4@0@0@0@0@0@0@0@0@0@0@0@0K0u4@0@0@0@0@0@0@0K0}4@0@0@0@0@0@0K04@0@0@0@0@0K04@0@0@0@0K04@0@0@0@0@0@0@0@0@0@0@0@0K04@0@0@0@0K04@0@0@0@0@0@0@0K04@0K04@0K04@0@0@0@0@0@0@0@0@0@0@0@0@0@0K04@0@0@0K04@0@0@0@0@0@0K04@0@0K04@0@0@0K04@0@0K04@0@0@0@0K04@0K04@0@0@0@0@0@0@0@0@0@0K04@0@0K04@0@0@0K04@0@0@0@0K04@0@0@0K04@0@0@0@0@0K04@0@0@0@0K05@0@0@0@0@0@0K05@0@0@0K0 5@0@0@0@0@0@008Pwv@0@0@0@0(@0(@0(@0(0|X  &&&)*4=JSY\etل*answ| ^I "x&)&.38;n?&FlIKNSQTX\%bgkpouz~ˈx ɔ ٮO#]Hoqrtuvxyz{}~pHQqQQE]`X_  /XR$\=j~SR$s37rSx~4n@ (    c <@@A art-fp1402C"?\  3 "` V   # "` B S  ?7 w^y:t Q-x'tt utb@u\Ou:uOuOuN uL u? u\= uDG u,@u Ynnmmll   vvrroo 9 *urn:schemas-microsoft-com:office:smarttagsplace8 *urn:schemas-microsoft-com:office:smarttagsCityB*urn:schemas-microsoft-com:office:smarttagscountry-region    jx}FO ) ~ 6?)2Q[HQ:Aal~<BRZ <BLUjs !!!!i$o$$$&&&&))**)///001144===>> >>>>#>??AABBCCCCCC3E;EfGoGHH?IHIJIOIVJ_JnKwKKKMMNNTO\O QQQ"Q,Q1QQQyWWWWWWWWWW[[\\PaVaZdbdhhhh$i-iii&j-jjjykkkkl ljlvlwllnn:oFoGoQopp)r2rrrss|stt[uiuvwPxVx*z2z3z>zzzS|Z|||||}&}~ gmu|pv~ބ.9ňLjΈވ(Αّ˛'*3C)4>I&5ipŷͷ ùҹ׹[efm 5:;DENNYZa kvr| qtmoV\f-o-55>6I66667>7l7>>2>?>??FF(L.LP#PRRWTfTZZ\\A]D]*^.^BgIgxxyyiysyyy!z)zzz{{V~b~~~~ ~lmJS#0#~CL3333333333333333333333333333333333333333333333333333#$;<QRefu [eO>O  ^ ) 7 )  ~PV/RcD 6xL Y !!!####'''())**////(1<1334w55>6K6'>2>?&?h??#@-@AABBC CCCfDD3EAEEEFFGGH0H2H8H?ISIJ JJJJJKK#L8LLLMMNNfOOOOpPPPFQHQQNWWXX\%\]];aPaaaaacccceZee f ffpggyjjllnopqr"rssttuuvvvvvvv wZxxxyz{{{{|}4}}}ʀwW}~ #GɌHmn^ޒWx XE}/1C;qr͛לٞ LZuܤĥȦ٦e~ F̨ 3>ʲgQ^I]ָyԼܼŽ\p3I)$ HI#<~O8Qo9V "g8aNۼ+v)b8VqDTvvպMu`Hbb " ęeP p/ nh -( : ,6SexSJpF<MqB *(NB:>Xtez[ZFjn8}i,^{t= lx&2$T!' sE.u>:B.#n(ۨ8 =l _F5p<lnOM x1!DU"k)U#=iNq#VF#hog#r6Bzy$L\&${J$.H4X%X1%0fei%nn}%!5k?&f6jI&x'v3'tN(g+)+3f1*Ԩ-b*dAX6j+$M ?-v;a.07/jo a1qvq1 $h~1G%P1PJR\!2V (2z]63dpf32(mV 38I0r4K:J42L\a 5u3?A5'x\5B'E6;g7:#}zO8"{Hb80t}99V`N2:W:*2W:z3;h=0^u>؞*~ ?ڊR&;AfcAwWBlZȚs BQ,qBBHBpqD,kDh$V- EY5E,n<~vE(P|JCQyJRd+RiSj }[TVF\T@(DTto\UCCKVrW(, WP=XVjVX4Y4(Y^sY&u"OY7'ZY(P4Z2zd|[l~q\Y| \,6K\֑4Ze^l_<x`P:+97Xa4u raRHw4aHge3clUYac/bkcԖOid |#"eEepyelQ f`OLgPJwiq>5>j.2J[bkp$.Tlx[nQo PDoH_-p2DDr)r* k'sl+u&A:jvUxvxz2*,$yjTya9z (Zw{$"Z|V|T*|q-}*Y[}&4 |*~CSynhT ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  88^8`OJQJo("  ^`OJQJo("    ^ `OJQJo("    ^ `OJQJo("  xx^x`OJQJo("  HH^H`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  88^8`OJQJo("  ^`OJQJo("    ^ `OJQJo("    ^ `OJQJo("  xx^x`OJQJo("  HH^H`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  88^8`OJQJo("  ^`OJQJo("    ^ `OJQJo("    ^ `OJQJo("  xx^x`OJQJo("  HH^H`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  88^8`OJQJo("  ^`OJQJo("    ^ `OJQJo("    ^ `OJQJo("  xx^x`OJQJo("  HH^H`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  88^8`OJQJo("  ^`OJQJo("    ^ `OJQJo("    ^ `OJQJo("  xx^x`OJQJo("  HH^H`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  88^8`OJQJo("  ^`OJQJo("    ^ `OJQJo("    ^ `OJQJo("  xx^x`OJQJo("  HH^H`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  88^8`OJQJo("  ^`OJQJo("    ^ `OJQJo("    ^ `OJQJo("  xx^x`OJQJo("  HH^H`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  88^8`OJQJo("  ^`OJQJo("    ^ `OJQJo("    ^ `OJQJo("  xx^x`OJQJo("  HH^H`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  88^8`OJQJo("  ^`OJQJo("    ^ `OJQJo("    ^ `OJQJo("  xx^x`OJQJo("  HH^H`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  88^8`OJQJo("  ^`OJQJo("    ^ `OJQJo("    ^ `OJQJo("  xx^x`OJQJo("  HH^H`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  88^8`OJQJo("  ^`OJQJo("    ^ `OJQJo("    ^ `OJQJo("  xx^x`OJQJo("  HH^H`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  88^8`OJQJo("  ^`OJQJo("    ^ `OJQJo("    ^ `OJQJo("  xx^x`OJQJo("  HH^H`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo(  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo("  ^`OJQJo("  ^`OJQJo("  pp^p`OJQJo("  @ @ ^@ `OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  ^`OJQJo("  PP^P`OJQJo(" 9zCKVsY9KYac ras BqDo9'r>XM_-p;a.Zw{k'sHBqLW:pf3LDGx,qB: CQj~ ?K\ " O~q\*|p/ ei%^{t|*~)b _P1=:I}99'ZRAO4Y = S?)NZe^m3P4X% PDo%\5:cA97Xa]ZLJR*,$yDNX6j+R\!2w4azd|[lTyq-}PEege3cJ4wiFP4Z}[TOid^u>eP P=XTk?&vq1M n&qI{Hb8a 5SyNq#5po\U W3f1*~vEF#0r4WBg#vv}pyeN2:3'h~1g7%E 1!T!V 3Vq"OY(Y2W:MBzy$kc6jI& DDrV- E]63B7/_\Tg8>:`H5EjVX-b*+)DU"{J$$.TlSex[nOLg(2 a1tN(+u|V|}zO8":8*t9@d [fg4г8B (-s)tRGH\z4FԤ8?Ϣrfv@pC: zLK"t$&P9$"+ `>H8l hy|".xFإ6ƬFҔsC@,1(h>B.>NVf\{ b:Ո\ ru` 4FrY’QI&p0kna0`0݂Gz^ hdQJ"b5"&>,@grvPl:]&f($ 2cL/Zv d(ꖼ\"|]`N^+0QV4^,`Tꡠ 5BNN68>?T>42F7o5 *.~xfReD"+` v8$t,@Hd-C@qP6NVRJG0x(S!&-ظ"I[Fd4=`Uތ`+Ŋ\§n^8\N6Eh`|,PjKiI4 QldzH0"`,?T8ġxԸ`h/1($ܾka&Bڮ0oLLw>K(<2&[ LBVȬԣaGpMHș B,!d*5\IdA@xB@ʲLTNH:t`;^ԶHZpZ5z$4V NW$fr묲L0>A{THzBJC>HIȄQfԨhīD@uzͼ2ο hh:~F9tIyn|`lZ@3FN> ddEdaX$k(B rWx0DFsGu]bg9Z`\RKQVTNT[vL|c9 )y論`XBux,xR;R *;y5f_TT[^R z€ؾ"Dq4N.d*L.}r } wċvh8 R>6bsm>/t}vegtۊxƼR԰48e%zRJx$8{,C֌X޹{2B@1ΈE >)/2t&$uĖVNʺ\_ՀKH:LoDS&Z" L.xV!";VR/$@3\*1pjD~گVaQڦ2HO4ͮ7PDVB\S:nEZx|<2N}̒M쵰tgZW~p"Zd Lvp( Φ\*ACc0r6N<>>ӞȈB Qtt00l$zߎp:W6SN_NP:pj x\JtN@D` z7%>k"CFqLF>DDv`pS б:rZj *.YҮA:6̊z >:7jZlT.!̍k s~ZȰbFbri(\pޱBFPrFAF@~'FhHV|"fPtHn JESd`_{ekj&Rx(Xa-xPv6:`,Gw:V̖#z؟n^ <l|K6mX^T`DmVG| *TNoP{tB{yJpt1BH-tBY4П0Bt~ `f3R3XZ霘iz&54j`.W@^)["t2T8d =R -@ ֤.͜אRx$6~O $4iv|T8Lh>&\vTp :~RTTMx{`I6BoY>|PSʔ~dgĴ(`6Iz 0)G2,B\X4^Nl8!濊LƌYV޽D.6}2HrNZn FƜܦqJyD^tXKdij,Pl%'Z)$}} :TPN/e@BTތn8֣,P4@.JE.ZMN(>׼qĆJY&M|˜#6/Vy ܑl$IR)Pa>(4]:) LN:jV=xr{fȞ6tQjN,v4o>tw~:\~fyzEp_tؤ73XEkP $њ$ؔT~"DTFf+ D蘨bNiB|ȱҞkEa*VxZS%خ&!Va9px6$HR$`(y\@_^.R8H&R|n1x|rl-T|Z2vGں`"y*kT*u j\TwlF<JFUt+>`E|d,@`ҳ#$jxmTz2hJ2Ő $߄D(6,""I*n@v$w,.N/zﰚ Kq^NP#6$xL"jd

g/.kXv@d2ҳBD=ފo$o8 ,ДCu LV  {Jnx +64X!p p0 $D٪6Y uVO~N\`;'[\d4v7La ! }R}/v^Ed,{kZ},:5dOS2Q`u`\H8ҁ0Nz"f'(ЋJΣH UtrjL`@srNb,,0!>ʁ,h qRlj|0~Aº< | G$ĺIJFZ]R$V 2$MW>(J:NѾGw6{~|AJgJ.p̩xtx Hz}̂X6%8Լ $p N`@T?N|Jqd67tb+ڻXU}X!nhV,ּTR^g0luf{Z|HE~G@ QyI "L.< `/v'0QT ~򬙒 m/2BH"2t> @6s:=@3LĮ BhR:%.$~x(M&<-t(P5{x;~jϸRb|j<1`@ ?Ԧ{`Կ2 e*O,(k:Џ&&vL^rD"2L p{l[MvNk ]'apb"jRT&7D4,o,b^=t(V-{:pWn`o&Τj6Ƹ|T 0i*p$\lj05]FuؠrnupЧJ"?W$.^x'.|d"섖 FFzcj,4IL@fPR0̰8? pD XĘhFG`!P6HuƳ 1XOv`=`zzv6@f]DxޜEƇ_,$^TZ\\b& n#BKΉ¥9wjx$(X>D6\Vd)dn) \.p(Д'@t/r60zZPpT+ثvXZZ0s~|2SO: nN R|֭^6j f^.3B6n`p;>t.ʓp=` zL-P~ Z.&վJ8h@lVbR$ }:A0.`!fZ6"!S6f*tun HP'^ګ@lV@ZH!$ڜ,0NN>,hѤ]BVOl pf *BzJ6j~&}X( vt[23JØ_6jz}j +&-ъD LrVX0|nn" }`ƹroz#R24-*0dKtlh:z3LVC [H^La;;!KHgX<@a66;]f7N>$XwZ2n}*bۖިk (Vnjb OD>ẍ́ f$i" *x܌@y<>zXZ\HffAf\RDO8H6t\p$`hy'g8H^:=~ʆ>'/.\' S_OdNrk6^ @m C ~m(JzJkVͬ Pτgd~L.[3/D%Оx G Řj@YP>." ib&&o[RVp*v\U1Z'&VÂӖ@hl>`$pUFRԸĮ]ؔ=R6G=Z~RָķO0ufb+&I[:Y^9JNŸ.BFw 'M wA8A>lu@NNw="Y5m(NBhSP~co,^nLj~3bjQr]fM1354D1TWL){nL9@;^z);\ x6'DsRSf5\S\9 c(:NB% ;D{x`#Lj9y38AST`sJ_^>g)zoHq}t ,Z0LZ -DqJ)U)O GRyPVbkD|Xa)%]c&F' RJY>q\)UN9vHM|y76?3[I9Fc u~ aKf1oy')TA-"WwV;FNz9@cxy;NBb9fu&D}oE,k4EKLF;|&9,e &1KH3z3]44Ev l^Wy/m(C-HnV0CMtM |}z4qWd _al`O#`i+`ohJD#~v-Hvjnb!cK,3P ww}H7OI>g):+, (|L6uJI 32^qW] :[|koPj:`| g T`sJ::TK:Diz n*;CqY,)muIn TY X{ x6 f2>y | . Fq $ jAd@`  J=7! *)Iro/ l&TMp f2\9 i;"pg $$W1 g% YhF6' 1 ]2 %dr )(O{ @@JS vHMKZ #h| P"<l E,k) r=  0 r9p% d. ". ]X1 #FS[@2 f5_ZG [I9F'M IW 5| H ?N A X$} & X$~i vg,D K0i$i KZ /X bL66 84R #L- bEGc &0(Mv  H H^ G5 MJH K P@' /G&H f1$#& 3m&F' .v@ 3 ]UK+H ~=1H yB1-R _V 9Y TWL&p YI o.| YY l{X LhWx uV] UU7? pg T V+> ~&CI!U@s*E,k"+LmuIuQbwY Y4aK<{@{muI! 6ancs;\ vz`bVb:M4s`&K PXP:`[==pq?<$"{OJFH?[kiKljnbBpu=&>qSd8QoW/+B9D>'\>. F$cg|M3G'0_{mOLLV0Cv^-M}$=hqC2=D7.?es)/&;Jb@n^YerX _3m/jT{7TVb_)'lDE#1q[^3)q="v}Gk0P1NBbwB(O{ $MkqUUtm6a Eq d^cmE q0|jp{~M |gO+ <VpaTSWdf=-p@3m@9|)G1&F' dV[YU'!G)ErS;D]4s"hODwYhFvx0E:c~hK:LpR9V%yWk/jc$&{mVg?DKB0ENwz35\Tyw[Dl,frAQ:Quo}wwZ) /BUgohJholu9{pqhDl$35CFcd;^xX/;RvZRvAnbrvV0Ch S4E K,% Y2&w1_ +NKE6N3G'A5b1eJ=7%yVV(WVp"b.%lbL6$ *:vHSKZ \@=SBQaSs6p@Mjxc GkY:c~]XpJ W<G/ ?rSnLt)R)[3oKhw 93D ]2 HnQS-?bL6gkm7WDlsmFH,nTWLpC w<uI7/M26?C4l{P?&^7mjlFJYd t.Dl]3G'vg-0_jj noI*nQjt1rZbS%?O+ <}\*amqXuUT]\jnb2^Xx<) D$o_v3*rC&B;H[MS"NPVb/,R,uu^o/ 4m-j^D~[k_Xyc6N1M|$muI;(C-K;Hxl46?O5$>&I$c[7up6 /BV+ =jjLhv(/~c{V+P0V0CpcjlF#+k%V5<~jGH7O#9,ez4V1G QO_tm(*tujvg:XN!nip#&x35L($=7QY$Dl,6bL6NP~coG Q x^JY!cpk<) pquh|KRSS%qgOsAQ0 c%STqC2uwVXsvI FHAL r }k- N@ KZ o &F' <) --& G qM nQ Hq_Z m)*5` Kd LKQ-$s ]f J W<a ^ nQ B !4mx&!KRSD/!A8AA2!D!4c!qB\!m)n!APE:X!Ly BX")%]0"7A>i;"\";\ ="?c@"qC2'"3ma"r"O+ < #ip=#`|@H#i=K#%y[j#P{#;r#&R#O5$ #oB#l#A8A&#mgp#4c!#H4-#B#I9$$ Q0S%$.a!B.$#E$H$ X$cs\*q$DlBq$6s$4t$x\QF$DlPj$z4]$2DA$X$$BE#z$0El %RE3%&5%"@]7%p<?%9@_~L%fU%vm]}\%jnb]%c%#+k%"u%B2|%FHC%K0i%E%A2!F%FHx&*~&u<n[ &] : &h| N&}Z=~S4&?B :7&lL&,PO&+H {t&K P[~&2^X-&wG-+'o/ v7']d?'QZ-'U@s?'jpm )'sZFT.'&@'T@7G'KZ TL'$  ['M~'X%sA'I'3m|W'1 r,'Z3G' h+(2$Q1 (v(}2FKZ(Nwc(a, (&Ay(3mVV((A'\6(o<?)0Eoy')f4)3 g)?L)#)O G?*~S4&tm(*k- ,*"2NB*G*>qoI*wW*tm(* d*Y:f*Fo|u*)-k*mb>* *b>*[*9@P +U^-+{b N+DEujT+r}b+3*Td+6Iq2o+EPi+QPul+-GMy+4Vx.+O+ <y+- 9+o/ h+\*a1+=HDM'++AV+Z%XZ0,{a^,P,~S4&${,v2F,'M V,>,vg|,4Ew,1KH:, /BJ,n!,3ml+-; -/GB7-I|X|(C-:6PLKQ-nf-9@{-ES -j}}A-D- ':)-1 '-2D&1-=SB+=-)-et-jz1g-^js--{-+H ty-Bpj4.J.,.}7cM>.=3A.#KN.8.hdg./[Cj.R)[-9p.jlF r.?.W(^#.I.&0(M/M.K P8.&.;D]o.q.Wk.<DuEk/YerXxX/a[/7A>{_/kD|"f/8Qo^r/.U/Yb//7A>8/:/n!/-Dq\/K PMA0A3.0Qak-?0kI0pT4Z0r=)a0 "I`Ea0'w g0D80z0#Ke0P?0Y5mN/0-Z:H0 Q0YU'Q0^Buwk0,Zj1?31uf| 10E0 11,ZE#1\q`416aXh81yB1NR1$ROZ1>&Ijw1]d]kw1Gk1Bpeo1{_/i1 YI1YerX1!FG1Ew1"1O+ <!'191'1;1vS0P1B9|;293|2i+W2{qC2GWM D2<Du&R2}Z=utd2EB[6Iq23`q2`|v2?~2jT+GL202[222-H"2i^^_ 32yvf2"1gx2$R 2`|D393ikk}f3yj3%s3S%v!t3,13PVbvR3N#hGK3~3E,k3?3t3A3)+k3}Z=?3 wgt 4P4l 4]A)4Iq>4^D~]]4e~i7Hzpq7&L`7V57}7c mw7{_/Zn7n $G7[7?D7y~ 82&d(8^-8JY{88P8-DqFS\8E#1D8% 8v!t3k8[huv8I8+^~w8d9>q.9bXn9b9<9489_g.9R;9m )'@9xWg9P~co- 9ta6M9n9}9j99BF99'wt9&0(Mc9& ]:9r=w9]A)4hz9G9$R:V0C] :ki6:p@Vb:[MD:gPM:xPS:] :i:P}:l %:e!*:ipAQ: ':V2:6?:)d:8/O-; ; +;Ll0;ueW*y7;F*xI;I8t"I; AL;D8oSN;;Cg;Qaeg;'D{z;KZ -~;9@U;;;';j#; ;f5h0;pxy;]%V<;RvO+ <cj3=r=t5Sc~=0h>_)j>f=>FH7A>(F6N>c>GK3>K,>$R)>Dlg?*)IrY?}_B?2^XI?jFE*)@9@,KDl<@zoJ@7U*N@aU2e@=r.v@A@@=IY*@E@I80@M |A8Ab/)X%A8Qo!=*A-AI8`CA.OAg ANqoAU@s4A$ A?3lA cAQ.W.A9A1 :A+ATB?EQhBqBJ.LB7TVb%KMBvHM!6aBmxB&B=SB{x(IB,Z}BQa B! /BBagt BKZ QB^DEOC}7LE$BEB#APE"\EC~=woEOuE4c E~2EyEaEs`EE,mW0Es$?EMtEj9qEE+H V;Fu@ujlF2e<sZFm[FVb:[I9F({T. LFWWGgbFo_v7cF="jF5kFE,k 2qFqW tFvHM>'uF~i7}2F(F!Fx6F7A>ogFr=YhF|V?FD-%F.aQ,G4 XM#G4V^R#GD><~jGO G;Il/GG;wGvCGohJ@+GvHMWWG|G=Hk^5H6?1KHD3UHRwHV./H1KHfH';DHH$BYHQ0M@HA=H?[FHte Hf1w%HcNHdHvmJ+H&NpH] : vHy38IqC2;aImuIj~n=ISYV@IjlFYInrIU fnIjBr$IO GZLI"J= YISquI* IX~I+IP~cocIP?rC2UJnc JWx t4Jcd@@J%qJ OT`sJH 6uJ_J)J,ZHJ4Vd`J>qHZJohJ  CJ1 JP~co PJJYV}J8zAKK3K2:KNwZ6DKf4)GOK<) T9vKVf xKV<d~KS%#KOtX.Q H bQ%c Q[p06Q vHnQhtl2$QGL23FQ'1HRM |$R*5` ^;R=SB>AR9|LR4miRRU@sh\R(C-jjR"RtTe!({TuUT?N aTyaTS-Tocc6TO GPT4 XuT:v TT@TnpT;c-U&5%vUU7TVb6nU>g)7U]4.U1&ilULqU_ +,5U@h~(V4mZHVY?wIV\7LRV{VV\MwV&0(Mo~V[j#Z;V%y#CV7A>2Z`|eZh-Z gS[LotV [A[4m*6[S-T`[[hZE[k5]QR)[{88 [[]UKRg[4m|s[ J[`Ek[1g-EB[dV[%[D\H\ A'\u?:]^^\:v|m_\m\ueWt\lz\m){\pRnW\c>'f\nL (\Qre0\e!\ d*D\P\QhBx\Y]_ +D ]TS]]r=& ] IAe)%]|m_\u?:]/W]0ER]]uV];D].5U^|`X^]^k^v.^ x^@k%^W(^A8^ q:^ipu<^{a^;!Cf^}Z=}n^*~et^1 v^FHmx^WkO|^^D~^==^\/^6a9s^, (<^mxB^*)Ird^fpL^>g) ^A-0_:__-M}M^`s?`|`)`9qOv`0C`4V "I`KS`)-tU`jnb+Z`4Dvz`{x`}9O#`y`Y5mHk`c(x;`s?`22&`\_Ua>g)7ja9wWai:\*agt 42b>aDEul ?avHMSEanOa_7_aU@s_ca{_/s~aa.ad_bbFb cp"b:7&JblL&7TVb3jCcb35jnb-#,bD b7U3bMcjbT*PbP-Am,b&F' bPVbNfVh%ciNchz9t5Sci^cm )'VycVb:b|c*)Ir~cf2]pcm )'>c4cZc&{Fc5| bci4cz}occ cjjD1cqC20d ,@~k d!3,dx$d4Da*dp"bOu>dqWjAd(dM=d[I9FmdcdA@~dGk*dB9{d]d0 1d>q#!@e?E IAeomPe *"ee:A?feQ09,eiE!e*)Ir{enLE eE,k+efU fK(fY(fnef\NVfdf fP4pf]UKauf&N2fKd Vf9fDEuzf&5%`ff&0(M#gRE3%4gE'gQ0l0g&0(MN1gM9"1gBagtgg g-g%y]dgmgh8g-Zl!g1MqgFgnOa@h3KnhvHMHh * -3h&0(Ml4hGTp8hqBNfVh^h<DuLhqM hnQ N#hQkuhMhJ W<'&3iLXCq9iq{ MiR`iB9\xi7TVbI i(C- :i"2'Ciw%H>i MiIi>qi,i:H0,iS%i#~v2iAX[i& ]!i2^XK0iaT1&iKi==^-iipi6});i"21Pj[j{j]dh'*j&0(M-j3jS,Lm3mO-;$*m *51m?W?Y5m>AR0`m==^P-Amgkm{4}mMvmZ)m35OmhZ@mcd!$mmVm4mtmZ)mCy^7m1en6N> n ;nC|>z Yn35m}nr }AnSEaJn:n35AnuivfnqW*nS-TPnLof&o-M} Io". 8Qov.^P~co.k{goO4ho<+|o7o1g-8o7vom)KoNVf^oDlFoHo1KHRpMgp)6)p+e j8p;^p9pjlF!GpS[p}HzpP_p*Pb6ppqjpj4.npTOpmuIzpe!r9pNrHptm(*fppV5ipcNHEq(O{ m6q?;8qf2[?ql+-NqI|X| Nqs~a\qsq"eeQxqmuImqwoE7qqC29q-Dq3SqNqu q!=*Akq6ozoqhZNrjBrrQr#.t}#rEsiO@r. F]]@r mZS*)Ir;aIOrm)2K^rf]zvr2^X`zvrS1{rAK/Ir89 ?r=r`.r_g.9jr O"r!$mrK0iU@sd. X%sTk*sWk .sDEu$2s%yaEsSshYs\_V4osu 32y`|&Ay)sGyPVbjy==^|}ypRy4EPy.U@=y%FPyy*@CynXy9y;\ ^y* ItyV<=myvHMf$!z==^Fx*zD8C|>zyBz [' #Cz:v6ozz1=zY5muz"2z35jzQ8zUq{>o{-Z7{<$"{(,{2$QH-{)-@CU{~[~[j{3{{&N08{J W<@{d$EF{y{P{#l{b6C{<3lNL{Z'{&{A$M |HZJ`|Py&g,|-ZF;|I|X|d(8Yd|[huo|5|;CB|\\Q|M9|{goY|Nw~|<) r }l:} }>Qf}35j}}lF}<DujZ}`|m}${,&}o+o}z}Q}L}M}7TVb-M}qEb~_~L%`*~D-v(/~K8~\*a ?~r= ,@~)XD~M~Yl~K(f~[~+^~e ~[pj~T`sJ3M~jz(~3m.~6~Vb:B~GT>~35HV0C/;C h+++=F2mI9@^undu&j qf!:'FZ3k8D;;=BiiBaFZIhSBc`|i~en0u 9vEH7 V! 4bB.d&X#[ t>8 DvWBsM\1H@HHZHH`@UnknownGz Times New Roman5Symbol3& z Arial;Wingdings"1hhqʦʦ Kdk|Kdk|!8894dDD 2QKX ?` 29/19/08bgmcbgmc                           ! " # $ % & ' ( ) * + , - . / 0 1 2 3 4 5 6 7 8 9 : ; < = > ? @ A B C D E F G H I J K L M N O P Q R S T U V W X Y Z [ \ ] ^ _ ` a b c d e f g h i j k l m n o p q r s t u v w x y z { | } ~  Oh+'0p   , 8 DPX`h9/19/08bgmc Normal.dotbgmc4Microsoft Office Word@@6V- 6@~} 6Kd՜.+,D՜.+,4 hp|   |kD 9/19/08 Title 8@ _PID_HLINKSAl]http://www.theraderm.com/t   !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_`abcdefghijklmnopqrstuvwxyz{|}~     !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_`abcdefghijklmnopqrstuvwxyz{|}~      !"#$%&'()*+,-./0123456789:;<=>?@ABCDEFGHIJKLMNOPQRSTUVWXYZ[\]^_`abcdefghijklmnopqrstuvwxyz{|}~Root Entry F; 6Data 1Table ^WordDocumentSummaryInformation(DocumentSummaryInformation8CompObjq  FMicrosoft Office Word Document MSWordDocWord.Document.89q