ࡱ> e CbjbjJJ ;(_b(_bgm jjjjj~~~8T $~;Q..(VVV " PPPPPPP$SUP9j PjjVV4P555 jVjVP5 P55V:@D;V-j2: P Q0;Q:TEVj2EVD;D;EVj; 5 PP4 ;Q EV B 0: CURRICULUM VITAE Last Updated: 06/22/20 PERSONAL INFORMATION Name: Orlando Mart Gutirrez, MD, MMSc Citizenship: USA Foreign Language(s): Spanish (moderate fluency) Home Address: 1513 Oak Leaf Trail, Vestavia, AL, 35243-5418 Phone: 617-459-1489 RANK/TITLE Hilda B. Anderson Endowed Chair in Nephrology Professor Department: Medicine Business Address: Zeigler Research Building 638, 703 19th St. S., Birmingham, AL 35294 Mailing Address: ZRB 638, 1720 2nd Ave. S., Birmingham, AL 35294-0006 Phone: 205-996-2736 Fax: 205-996-6465 Email: ogutierrez@uabmc.edu HOSPITAL AND OTHER (NON ACADEMIC) APPOINTMENTS: 06/2002-06/2008 House Officer, Massachusetts General Hospital, Boston, MA 07/2005-06/2008 House Officer, Brigham and Womens Hospital, Boston, MA 08/2006-06/2008 Consultant, Massachusetts Eye and Ear Infirmary, Boston, MA 07/2008-12/2010 Physician, Jackson Memorial Hospital, Miami, FL 07/2008-12/2010 Physician, University of Miami Hospital, Miami, FL 01/2011- Physician, University of Alabama Hospital, Birmingham, AL 01/2011-2013 Physician, Cooper-Green Mercy Medical Center, Birmingham, AL 02/2012-2018 Physician (WOC), Veterans Affairs Medical Center, Birmingham, AL PROFESSIONAL CONSULTANTSHIPS: none EDUCATION: Years Degree Institution 08/1994-05/1996 none Columbia University, New York, New York 08/1996-05/1998 BS, Biology John Carroll University, University Heights, OH, summa cum laude 08/1998-05/2002 MD University of Toledo College of Medicine, Toledo, OH 09/2006-05/2008 MMSc Harvard Medical School, Boston, MA MILITARY SERVICE: none LICENSURE: 2004-2009 Massachusetts Medical License (#220307) 2008-2012 Florida Medical License (#ME 101493) 2011- Alabama Medical License (#MD.30625) BOARD CERTIFICATION: 2005-2015 Board Certified, Internal Medicine 2007- Board Certified, Nephrology (re-certified, December 18th, 2017) POSTDOCTORAL TRAINING: Years Degree Institution 07/2002-06/2003 Intern in Internal Medicine Massachusetts General Hospital 07/2003-06/2005 Resident in Internal Medicine Massachusetts General Hospital 07/2005-06/2008 Clinical and Research Fellow in Nephrology BWH/MGH Joint Nephrology Fellowship ACADEMIC APPOINTMENTS: Years Rank/Title Institution 07/2002-06/2008 Clinical Fellow in Medicine Harvard Medical School 07/2006-06/2008 Research Fellow in Medicine Harvard Medical School 07/2008-12/2010 Assistant Professor of Medicine University of Miami 01/2011-09/2013 Assistant Professor of Medicine University of Alabama at Birmingham 02/2011-11/2016 Assistant Professor of Epidemiology University of Alabama at Birmingham 10/2013-09/2018 Associate Professor of Medicine University of Alabama at Birmingham 12/2016-10/2018 Associate Professor of Epidemiology University of Alabama at Birmingham 10/2018- Professor of Medicine University of Alabama at Birmingham 11/2018- Professor of Epidemiology University of Alabama at Birmingham AWARDS/HONORS: 1997 Howard Hughes Summer Research Fellow (Case Western Reserve University; supervisor: Matt Warman, MD) Donald H. Clifford Memorial Scholarship (University of Toledo College of Medicine) 2001 Medical College of Ohio (now known as University of Toledo College of Medicine) Satellites Scholarship for Academic Achievement 2002 Medical College of Ohio Microbiology and Immunology Award 2002 Alpha Omega Alpha Honor Medical Society 2002 American College of Physicians Outstanding Student Entering Internal Medicine 2002 Medical College of Ohio Deans Award 2005 1st Place Resident Clinical Research Award, Department Of Medicine (abstract) 2005 Massachusetts General Hospital Clinical Research Award 2006 American Kidney Fund-Genzyme Clinical Scientist in Nephrology Fellowship 2007 NIH Clinical Loan Repayment Program Award Recipient 2008 Valedictorian, Scholars in Clinical Science Program 2014 Education Supplemental Award (in recognition of outstanding evaluations by medical students and residents) 2017 Graduate Deans Award for Excellence in Mentorship 2017 Max Cooper Award for Excellence in Research 2017- Hilda B. Anderson Endowed Chair in Nephrology 2018 Jack W. Coburn Visiting Professor, University of California, Los Angeles 2019 American Society of Clinical Investigation PROFESSIONAL SOCIETIES: 2002-2008 Massachusetts Medical Society 2007- American Society of Nephrology 2008- National Kidney Foundation 2011- Southern Society of Clinical Investigation 2013-2014 American Society of Nutrition 2013- American Heart Association 2019- American Society of Clinical Investigation COUNCILS AND COMMITTEES: 2010- American Kidney Fund Clinical Scientist in Nephrology Committee (grant review) 2014-2017 Chair, American Kidney Fund Clinical Scientist in Nephrology Committee 2011-2017 Trustee, American Kidney Fund Board of Trustees 2013-2017 Chair, Medical Advisory Committee, American Kidney Fund 2013-2017 Executive Committee, American Kidney Fund Board of Trustees 2011- Clinical and Translational Research Committee, Nephrology Research and Training Center, University of Alabama at Birmingham 2012-2013 American Society of Nephrology Kidney Week 2013 Program Committee 2016- Chair, Steering Committee, for the CALISTA study (Phase 3, randomized placebo-controlled clinical trial of intravenous sodium thiosulfate for acute calciphylaxis) 2017- Member, Oversight Advisory Committee for the American Heart Association Strategically Focused Research Awards 2018- Biosample Research Advisory Group, Reasons for Geographic and Racial Differences in Stroke (REGARDS) study 2019- Member, Executive Committee, Chronic Kidney Disease Biomarkers Consortium 2019- Member, Steering Committee, Chronic Kidney Disease Prognosis Consortium 2020- American Society of Nephrology Grants Review Committee UNIVERSITY ACTIVITIES: University of Miami Miller School of Medicine 2009 Outside referee for faculty promotion recommendation, University of Pittsburgh School of Medicine, Steven L. Kanter, M.D., Vice Dean 2010 University of Miami Miller School of Medicine Admissions Committee University of Alabama at Birmingham 2011- Section Head, Outcomes and Epidemiology Research, Division of Nephrology 2011- Member, Comprehensive Diabetes Center 2011- Scientist, Diabetes Research Center 2011- Associate Scientist, Nutrition Obesity Research Center 2012-2016 Associate Scientist, Center for Metabolic Bone Disease 2013 Search Committee, Director of the Division of Gerontology, Geriatrics and Palliative Care 2014 Outside referee for faculty promotion recommendation, University of California at Los Angeles, Sherin Devaskar, MD, Assistant Vice Chancellor of Childrens Health, UCLA 2014- Department of Medicine Outcomes and Effectiveness Recruitment Committee 2014- University of Alabama Health Services Foundation General Endowment Fund Patient-Oriented Research Grant Application Review Committee 2014-2017 School of Medicine Admission Committee 2015-2017 Department of Medicine Culture Work Group 2015 UAB School of Medicine/Nutrition Obesity Research Center Faculty Recruitment Search Committee 2015 School of Medicine AMC21 Multi-Investigator Grant reviewer 2015 School of Medicine AMC21 Blue Sky Grant reviewer 2015 Selection Committee for the Endowed Professorship in Transplant Nephrology Clinical Research 2015-2019 Division of Nephrology Promotion and Tenure Committee 2015- UAB Center for Clinical and Translational Science KL2 grant review 2016- Medical Director, Bionutrition Unit, CCTS 2017- Chair, University of Alabama Health Services Foundation General Endowment Fund Patient-Oriented Research Grant Application Review Committee 2017 Outside referee for faculty promotion recommendation, University of Miami Miller School of Medicine, Roy E. Weiss, MD, PhD, Chair of Medicine 2018 Outside referee for faculty promotion recommendation, Northwestern University Feinberg School of Medicine, Douglas E. Vaughan, Chair of Medicine 2019 Outside referee for faculty promotion recommendation, Indiana University, Mark W. Geraci, MD, Chair, Department of Medicine 2019- Graduate Faculty Level 1 appointment, Graduate School, UAB 2019 Outside referee for faculty promotion recommendation, University of California, San Diego, Wolfgang Dillman, MD Chair, Department of Medicine 2019 Outside referee for faculty promotion recommendation, University of Michigan, Subramaniam Pennathur, MD, Chief, Division of Nephrology, Department of Medicine 2019 Outside referee for faculty promotion recommendation, University of Toledo, Lance Dworkin, MD, Chair, Department of Medicine 2019 Outside referee for faculty promotion recommendation, University of Colorado, Michel Chonchol, MD, Chief, Division of Nephrology, Department of Medicine 2019- Associate Director, Division of Nephrology, UAB 2020- Senior Scientist, Center for Clinical and Translational Science 2020- Deputy Director, Center for Clinical and Translational Science EDITORIAL BOARD MEMBERSHIPS AND PEER REVIEW: Editorial Responsibilities/Editorial Boards 2012-2016 Associate Editor, BMC Nephrology 2017- Associate Editor, Clinical Journal of the American Society of Nephrology 2013-2016 Faculty of 1000 contributing member, mineral metabolism and kidney section 2014-2016 Editorial Board, Clinical Journal of the American Society of Nephrology 2014- Editorial Board, Frontiers in Medicine, Nephrology section 2016- Editorial Board, Kidney International Reports 2019- Editorial Board, the Journal of Renal Nutrition Ad Hoc Peer Reviewer for the following journals: Renal: Clinical Journal of the American Society of Nephrology; American Journal of Kidney Disease; Nephrology Dialysis and Transplantation; Journal of the American Society of Nephrology; Kidney International; American Journal of Physiology- Renal Physiology; International Journal of Nephrology and Renovascular Disease; International Journal of Artificial Organs; American Journal of Transplantation; American Journal of Nephrology; Clinical Nephrology; Nephron; Nephrology; Advances in Chronic Kidney Disease; Indian Journal of Nephrology; BMC Nephrology Other Subspecialty: Circulation; Journal of Bone and Mineral Research; Journal of Clinical Endocrinology and Metabolism; American Journal of Hypertension; Journal of Human Hypertension; Journal of Inflammation Research; Current Diabetes Review; Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy; Annals of Clinical Biochemistry; American Journal of Preventative Medicine; Journal of Clinical Metabolism & Diabetes; Obesity; Nutrition Research; Translational Research; European Journal of Heart Failure; American Heart Journal; Journal of the American College of Cardiology Heart Failure; Atherosclerosis General: The New England Journal of Medicine; Journal of the American Medical Association; The Lancet; Archives of Internal Medicine; PLoS One; The American Journal of the Medical Sciences; Pediatrics Other Peer Review Activities: Abstract Reviewer, American Society of Nephrology Annual Meeting (2009, 2011, 2012, 2013, 2014, 2015, 2016, 2017, 2018, 2019) Abstract Category Chair (Health Maintenance, Nutrition and Metabolism: Basic), American Society of Nephrology Annual Meeting, 2018 Ad Hoc Reviewer, National Institutes of Health; Special Emphasis Panel: R01 Grant application (December 2009) Ad Hoc Reviewer, American Heart Association Cardiorenal Grant Section (March, 2012; April 2013; April 2014; April 2016) Ad Hoc Reviewer, Austrian Science Fund (FWF) Clinical Research (KLIF) project grant (July, 2012; June, 2013) Ad Hoc Reviewer, National Institutes of Health; Kidney, Nutrition, Obesity and Diabetes (KNOD) Study Section (October, 2012; June, 2014; October 2017; June 2019) Ad Hoc Reviewer, National Institutes of Health; NIDDK Intramural grant program (March, 2014) Ad Hoc Reviewer, National Institutes of Health; Neurological, Aging and Musculoskeletal Epidemiology (NAME) Study Section (February, 2015) Ad Hoc Reviewer, National Institutes of Health; Diabetic Complications Consortium Pilot and Feasibility Program, (August, 2017) Ad Hoc Reviewer, National Institutes of Health; Biomarkers for diabetes, digestive, kidney and urologic disease using biosamples from the NIDDK repository (September, 2017) Ad Hoc Reviewer, National Institutes of Health; Special emphasis panel (ZRG1 PSE-V 59), Surgical Disparities, (March 2017, November 2017, October 2018) Ad Hoc Reviewer, AXA Research Fund Junior Research Fellowship, European Science Foundation (April 2015) Ad Hoc Reviewer, American Heart Association Merit Award, March 2017 Ad Hoc Review, National Institutes of Health; Special emphasis panel (2019/10 ZDK1 GRB-M [04]), NIDDK Pain and Opioid Use in Hemodialysis Review, (August, 2019) Ad Hoc Review, National Institutes of Health; ZRG1 PSE-E 02 (Chronic Diseases and Epidemiology) (March, 2020) Standing member, Kidney, Nutrition, Obesity and Diabetes (KNOD) Study Section, 2020-present MAJOR RESEARCH INTERESTS: Our groups research efforts are concentrated in three major areas: The relationships between disturbances in mineral metabolism and clinical outcomes, with a special interest in behavioral and environmental exposures that may modulate this pathways. Within this area of interest, we have primarily focused on the connections between disturbances in phosphorus metabolism and cardio- and cerebrovascular morbidity and mortality, including the emerging role of fibroblast growth factor 23 (FGF23). The reciprocal relationships between disturbances in mineral and iron metabolism in individuals with chronic kidney disease, with a particular focus on novel regulators of iron such as hepcidin and soluble hemojuvelin. The role of nutrition in the development and progression of metabolic complications related to kidney injury, focusing on the role of advanced glycation end-products in the pathophysiology of inflammation, insulin resistance and endothelial dysfunction in patients with chronic kidney disease. TEACHING EXPERIENCE: Lectures or Small Groups 2007 Residents Report, Department of Medicine Massachusetts General Hospital Unknown cases (discussant) Department of Medicine residents, Harvard medical students 2007-2008 Tutor, nephrology module, first-year pathophysiology course, Harvard Medical School: responsible for leading small group sessions related to renal pathophysiology among Harvard medical students. 2007 Neuro-Intensive Care Fellowship Lecture Series, Massachusetts General Hospital/Brigham and Womens Hospital. Lecture titles: Hyponatremia in the Neuro-ICUtelling the difference between SIADH and cerebral salt wasting and Renal Replacement Therapy in the ICU 2008-2009 Section leader, second-year pathophysiology course, nephrology module, University of Miami Miller School of Medicine: responsible for leading small group sessions related to renal pathophysiology among medical students. 2011-2013 Faculty supervisor, Introduction to Medicine II & III: responsible for leading small group sessions related to physical exam and case presentation skills for first year medical students at UAB. 2011-2017 Section leader for small group sessions, Renal Module, School of Medicine Pre-clerkship Curriculum, UAB: responsible for co-leading small group sessions related to renal pathophysiology among first-year medical students 2012- Lecturer, Renal Module, School of Medicine Pre-clerkship Curriculum, UAB: Evaluation and Treatment of Disorders of Electrolytes III: Calcium, Phosphorus, Magnesium. 2013- Lecturer, Graduate Biological Sciences 751 nephrology lecture series, UAB: Regulation of Extra-Cellular Fluid Volume and Fundamental of Acid-Base Regulation. 2015- Lecturer, Department of Epidemiology 602 Epidemiology of Cardiovascular Diseases Module: Epidemiology of Kidney Disease. Mentorship Experience 2009 Research advisor for nephrology fellow, Chhavi Gupta, MD. Led to poster presentation at the American Society of Nephrology annual convention in 2009. Dr. Gupta is now in private practice (nephrology) in the Tampa, FL area. 2009-2010 Research mentor for nephrology fellow, Cristiane Carvalho, MD. Led to poster presentation at the American Society of Nephrology annual convention in 2010 and first-author publication in Clinical Nephrology in 2011. Dr. Carvalho is now in private practice (nephrology) in the Miami, FL area. 2010 2011 Research advisor for dietician and study coordinator, Jessica Houston, BS, MT. Led to poster presentation at the National Kidney Foundation Spring Clinical Meetings 2011 which won award for being among the top 3 posters presented (out of ~400 posters). The results of the study led to a first-author publication for Jessica in the Journal of Renal Nutrition in 2011. Ms. Houston is currently a graduate student at Johns Hopkins Bloomberg School of Public Health. 2011 Research supervisor for medical student Andrew Klinger during Summer Research Enrichment Program. Led to poster presentation at the University of Alabama School of Medicine Medical Student Research Day in 2011. Poster won award for being the best poster in the group presented. Dr. Klinger is now a resident in Mobile, AL. 2012-2014 Research mentor for Post-doctoral scholar Lynae Hanks, PhD, RD on the UAB Interdisciplinary Training in Kidney-Related Research Grant (T32 DK007545). Dr. Hanks is now an Assistant Professor of Dietetics and Nutrition at the University of Montevallo. 2012 Collaborator on the K01 application of Wenjie (Jacky) Chen, PhD, Post-doctoral Fellow in the laboratory of Herbert Y. Lin, MD, PhD, Program in Anemia Signaling Research, Division of Nephrology, Program in Membrane Biology, Center for Systems Biology, Massachusetts General Hospital, Boston, MA 2012 Collaborator and member of scientific advisory committee for K01 application of Chia Chi Sun, PhD, Post-doctoral Fellow in the laboratory of Herbert Y. Lin, MD, PhD, Program in Anemia Signaling Research, Division of Nephrology, Program in Membrane Biology, Center for Systems Biology, Massachusetts General Hospital, Boston, MA 2013- Research mentor for Bhupesh Panwar, MD. Primary mentor on a Frommeyer Fellowship in Investigative Medicine Application. Primary mentor on K23 grant. Primary mentor on American Heart Association Mentored Clinical and Population Research Award 2014 Research mentor for nephrology fellow Claretha Lyas, MD. Dr. Lyas is now an Assistant Professor of Medicine in the Division of Nephrology at the University of Alabama at Birmingham. 2014-2016 Research supervisor for medical student Jennifer L. Jackson during Summer Research Enrichment Program 2016 Research supervisor for medical student Sarah Jackson during the Summer Research Enrichment Program 2016- Research supervisor for medical student Shejuti Paul during the Summer Research Enrichment Program 2016 co-mentor on a KL2 and K23 application of Pankaj Arora, MD, cardiology Assistant Professor at UAB; K23 received a score of 19. 2017- Research supervisor for Luke Bailey, medical student 2017- co-mentor on K23 application for Alian Al-Balas, MD, nephrology Assistant Professor at UAB 2017- co-mentor on K23 grant from Ellen Eaton, MD, infectious disease Assistant Professor at UAB 2019 co-mentor on K23 grant application from S. Justin Thomas, PhD, Assistant Professor in the Department of Psychiatry at UAB Other 2012-2014 Dissertation Committee Member and co-sponsor for the Ruth L. Kirschstein National Research Service Award for Individual Predoctoral Fellows (F31) application of Shawona Daniels, RN, MSN, CRNP, doctoral student in the UAB School of Nursing. 2013-2014 Dissertation committee member for Rikki J. Tanner, MPH, doctoral student in the Department of Epidemiology, School of Public Health, UAB. 2015-2016 Dissertation committee member for Luz Aly Padilla, MD, Masters degree student in the Department of Epidemiology, School of Public Health, UAB. 2017 Dissertation committee member for Marquita Gray, Masters degree student in the Department of Epidemiology, School of Public Health, UAB 2018 Dissertation committee member for Reham Soliman, MBBS, PhD degree student in the Graduate Biomedical Sciences Program, School of Medicine, UAB 2019 Dissertation committee member for Ninad Chaudhary, MBBS, PhD degree student in the Department of Epidemiology, School of Public Health, UAB 2020 Dissertation committee member for Kylie Heitman, PhD degree student in the Graduate Biomedical Sciences Program, School of Medicine, UAB MAJOR LECTURES AND VISITING PROFESSORSHIPS: Local 1. Massachusetts General Hospital Clinical Research Day. Research Award Lectures: Fibroblast growth factor 23 and hyperphosphatemia in chronic kidney disease. Medicine faculty, fellows, and residents at MGH. 2005. 2. Massachusetts General Hospital Center for Renal Education. Invited Lecture: Dialysis access options. Patients with pre-dialysis chronic kidney disease. 2007. 3. Look AHEAD clinical study. Invited presentation: Kidney disease in patients with diabetes. Subjects enrolled in the Look AHEAD clinical study. 2007. 4. Nephrology Grand Rounds, Massachusetts General Hospital. Title: Phosphorus and Cardiovascular Disease in Chronic Kidney Disease: the Implications of Race. Faculty and staff of the Nephrology Division at MGH. 2008. 5. Nephrology Grand Rounds, University of Miami. Title: Phosphorus and Adverse Outcomes in Chronic Kidney Disease: the Implications of Race. Faculty, Fellows and staff of Division of Nephrology at UM. 2008. 6. Endocrinology, Diabetes and Metabolism Divisional Research Conference, University of Miami. Invited Lecture: Phosphorus metabolism in health and chronic kidney disease: implications of race. Faculty, fellows and staff of the Division of Endocrinology. 2009. 7. Clinical Cardiology Conference, Cardiovascular Division, Department of Medicine, University of Miami Hospital. Invited Lecture: Left ventricular hypertrophy in chronic kidney disease: emerging insights into the phosphorus connection. Faculty and staff of the UMH cardiovascular division. 2010. 8. Medical Grand Rounds, University of Alabama at Birmingham. Title: Evolving Perspectives of Cardiovascular Risk Management in Chronic Kidney Disease. Faculty and staff of Department of Medicine at UAB. 2011. 9. Nephrology Research and Training Center Seminar. Title: Clinical and translational research supporting fibroblast growth factor 23 as a novel cardiac pathogen. Faculty and staff of the Division of Nephrology at UAB. 2011. 10. Vascular Biology and Hypertension Program Seminar. Title: Non-traditional risk factors for cardiovascular disease in chronic kidney disease: the importance of phosphorus metabolism. Members of the Vascular Biology and Hypertension Program, UAB. 2011. 11. Clinical Research Seminar, Department of Medicine, University of Alabama at Birmingham. Title: Fibroblast growth factor 23: the rise of a cardiotoxic hormone. Faculty, residents and fellows of the Department of Medicine at UAB. 12. Epidemiology Seminar, School of Public Health, University of Alabama at Birmingham. Title: Challenges in micronutrient intake assessment in epidemiological research: the phosphorus example. Faculty and studies of the Department of Epidemiology at UAB 13. Advanced Practitioners Nephrology Academy, University of Alabama at Birmingham. Title: Nutrition and progression of chronic kidney disease. Advanced practitioners specializing in the care of patients with chronic kidney disease in the Birmingham area. 2012 14. UAB 8th Annual Health Disparities Symposium. Invited talk. Title: Phosphorus metabolism in the modern era: when physiology must contend with changing diets. 2013 15. Medical Grand Rounds, University of Alabama at Birmingham. Title: Phosphorus metabolism and the modern diet. Faculty and staff of Department of Medicine at UAB. 2014 16. 25th Annual Vascular Biology & Hypertension Symposium, University of Alabama at Birmingham. Title Vitamin D deficiency, inflammation and albuminuria. 2014 17. Clinical Research Seminar, Department of Medicine, University of Alabama at Birmingham. Title: Patient-oriented research: bridging the gap between epidemiology and clinical trials. Faculty, residents and fellows of the Department of Medicine at UAB. 2014 18. Epidemiology Seminar, School of Public Health, University of Alabama at Birmingham. Title: Phosphorus metabolism and the modern diet. Faculty and studies of the Department of Epidemiology at UAB. 2015 19. Southeastern Clinical Club. Title Phosphorus metabolism in the modern diet. Members of the Southeastern Clinical Club. Birmingham, AL 2015. 20. 29th Annual Vascular Biology & Hypertension Symposium, University of Alabama at Birmingham. Title Inflammation, iron and fibroblast growth factor 23: implications for the heart. 2018 21. Cardiology Grand Rounds, University of Alabama at Birmingham. Title: Cardiorenal syndrome. Division of Cardiovascular Disease faculty and staff. 2018 22. Nephrology Research and Training Center Seminar. Title: Phosphorus and the kidney. Faculty and staff of the Division of Nephrology at UAB. 2019 23. UAB Comprehensive Cardiovascular Center 8th Annual Symposium. Invited talk: Diurnal Salt Intake and Diurnal Blood Pressure Rhythm 2019 24. UAB Comprehensive Cardiovascular Center Seminar Series. Invited Presentation: Iron for the treatment of heart failurenew horizons. 2020 National/International 1. American Kidney Fund Board of Trustees Meeting. Presentation: Phosphorus and cardiovascular disease in chronic kidney disease. Members of the Board of Trustees of the AKF. Washington, D.C. 2006. 2. American Kidney Fund Board of Trustees Meeting. Presentation: Phosphorus and cardiovascular disease in chronic kidney disease: the implications of race. Members of the Board of Trustees of the AKF. Bethesda, MD. 2007. 3. Chronic Renal Insufficiency Cohort Study (CRIC) Steering Committee, University of Pennsylvania. Presentation: Fibroblast growth factor 23 and outcomes in patients with chronic kidney disease. Investigators and staff of the CRIC steering committee. Philadelphia, PA. 2008. 4. National Kidney Foundation Spring Clinical Meeting. Educational symposium: Fibroblast growth factor 23: novel insights into phosphorus and vitamin D metabolism. Nephrologists from across the U.S. Dallas, TX. 2009. 5. Annual Meeting of the Carolinas Chapter of the American Association of Clinical Endocrinologists. Invited Lecture: Secondary Hyperparathyroidism in Chronic Kidney Disease. Clinical endocrinologists from North and South Carolina. Asheville, NC. 2009. 6. Grand Rounds, Nephrology Division, Cleveland Clinic Foundation. Invited Lecture: Fibroblast Growth Factor 23: novel insights in vitamin D and phosphorus metabolism. Faculty, fellows and staff of Nephrology Division at CCF. Cleveland, OH. 2009. 7. American Society of Nephrology, Annual National Meeting. Education symposium: The role of fibroblast growth factor 23 in chronic kidney disease-metabolic bone disorder. Nephrologists and researchers from across the world. San Diego, CA. 2009. 8. Selective Vitamin D Receptor Activation and the Cardio-Renal Syndrome Conference. Invited Lecture: An epidemiological perspective of VDR activation and FGF23. Nephrologists and researchers from around the world. Paris, France 2010. 9. National Kidney Foundation Spring Clinical Meeting. Invited Presentation: Fibroblast Growth Factor 23 and Mortality in Dialysis Patients and in Chronic Kidney Disease. Nephrologists from across the U.S. Orlando, FL. 2010. 10. Nephrology Research and Training Center Seminar, University of Alabama at Birmingham. Invited Lecture: Fibroblast Growth Factor 23: novel insights in vitamin D and phosphorus metabolism in chronic kidney disease. Faculty and staff of the Division of Nephrology at UAB. Birmingham, AL. 2010. 11. Epidemiology Seminar, School of Public Health, University of Alabama at Birmingham. Invited Lecture: The impact of socioeconomic status on diet and serum phosphorus: emerging interconnections in health and in chronic kidney disease. Faculty and staff of the UAB School of Public Health. Birmingham, AL. 2010. 12. Special Seminar, Renal Division, Brigham and Womens Hospital, Harvard Medical School. Invited presentation: The impact of socioeconomic status on diet and serum phosphorus: emerging interconnections in health and in kidney disease. Faculty and staff of the BWH Renal Division. Boston, MA. 2010. 13. Annual Convention of the Society of Nephrology and Hypertension of Puerto Rico. Invited Lecture: Fibroblast Growth Factor 23 and Bone Disease in Chronic Kidney Disease. Nephrologists from Puerto Rico and the Caribbean. San Juan, PR. 2010. 14. Pediatric Nephrology Seminar XXXVIII. Invited Lecture: Fibroblast growth factor 23 and cardiovascular disease in chronic kidney disease. Pediatric nephrologists from around the United States. Miami, FL, USA, 2011 15. 56th Congress of the Japanese Society of Dialysis and Transplantation. Educational Symposium: The importance of vitamin D receptor activation in CKD: beyond calcium homeostasis. Nephrologists from across Japan. Yokohama, Japan, 2011. 16. American Society of Nephrology, Annual National Meeting. Invited talk: Updates in Phosphorus and Alkaline Phosphatase Metabolism. Nephrologists and researchers from across the world. Philadelphia, PA. 2011. 17. Endocrine Club, Southern Society of Clinical Investigation Annual Meeting. Invited talk: Fibroblast growth factor 23: emerging links with cardiovascular disease, metabolic syndrome, and bone disease. Endocrinologists from around southeastern United States. New Orleans, LA, 2012. 18. International Dietary Phosphorus Consensus Conference. Invited Talk: Socioeconomic status and dietary phosphorus exposure. Nephrologists, dieticians, and nurse specialists in renal nutrition from across the world. Honolulu, HI, 2012. 19. XVI International Congress on Nutrition and Metabolism in Renal Disease. Invited Talk: Fibroblast growth factor 23 and Klotho: how do they relate to vitamin D and beyond? Nephrologists, dieticians, and nurse specialists in renal nutrition from across the world. Honolulu, HI, 2012. 20. Swedish Medical Center Update in Kidney Transplant. Invited Talk: Update in bone and mineral metabolism after transplant. Nephrologists, dieticians and nurse specialists in transplant from the Seattle area. Seattle, WA, 2012. 21. American Society of Nephrology, Annual National Meeting. Invited talk: Mechanisms of perturbed phosphorus homeostasis in chronic kidney disease. Nephrologists and researchers from across the world. San Diego, CA, 2012 22. Renal Research Conference, Mount Sinai School of Medicine. Invited talk: Phosphorus metabolism in the modern era: how physiology must contend with changing diets. Faculty, fellows and staff of the Mt. Sinai Division of Nephrology, New York, New York, 2013. 23. Nephrology Grand Rounds, Massachusetts General Hospital. Invited talk: Racial disparities in CKD outcomes: lessons learned over the past ten years. Faculty, fellows and staff at the Massachusetts General Hospital Division of Nephrology, Boston, MA, 2013 24. Joint Brigham and Womens Hospital/Massachusetts General Hospital Grand Rounds Series. Invited talk: Phosphorus metabolism in the modern diet: what we know and what we need to learn. Faculty, fellows and staff at the Massachusetts General Hospital and Brigham and Womens Hospital Nephrology divisions, Boston, MA, 2013 25. 2013 Scientific Sessions and Annual Meeting of Experimental Biology, American Society of Nutrition special session: Factors affecting high phosphorus intake and cardiovascular disease risk. Boston, MA, 2013 26. National Medical Association Annual Convention and Scientific Assembly, Internal Medicine Section. Invited talk: New insights into pathophysiology of mineral bone disease and its cardiovascular complications in patients with kidney disease. Toronto, CA, 2013 27. American Society of Nephrology, Annual National Meeting. Invited talk: Fibroblast growth factor 23 and cardiovascular disease in chronic kidney disease and its role as a potential therapeutic target. Nephrologists and researchers from across the world. Atlanta, GA. 2013 28. Alabama Chapter of the American College of Cardiology Professional Practice Improvement for Cardiac Physicians and Cardiac Advance Practice Clinicians 2014 Winter Conference. Invited talk: Renal Disease in Cardiac Patients. Birmingham, AL, 2014. 29. Renal Grand Rounds, University of California, San Diego. Invited talk: Phosphorus metabolism and the modern diet. Faculty, fellows and staff at UCSD, La Jolla, CA, 2014. 30. Renal Grand Rounds, Columbia University. Invited talk: Phosphorus metabolism and the modern diet. Faculty, fellows and staff at Columbia University Division of Nephrology, New York, NY, 2014 31. National Kidney Foundation 2014 Spring Clinical Meetings Breakfast Symposium: Clinical Aspects of Fibroblast Growth Factor 23 in Chronic Kidney Disease. Health practitioners in nephrology from across the U.S. Las Vegas, NV, 2014. 32. American Nephrology Nurses Association 2014 Fall Meeting. Invited Talk: Strategies to reduce cardiovascular risk in chronic kidney disease. Nurses from across the U.S. Savannah, GA, 2014. 33. Renal Grand Rounds Seminar, Vanderbilt University. Invited Talk: Peering through the FGF23 looking glass, darkly. Faculty, fellows and staff of the Division of Nephrology and Hypertension, Vanderbilt University, Nashville, TN, 2014. 34. Renal Research Conference, Vanderbilt University. Invited Talk: Phosphorus metabolism and the modern diet. Faculty, fellows and staff of the Division of Nephrology and Hypertension, Vanderbilt University, Nashville, TN, 2014. 35. National Kidney Foundation 2015 Spring Clinical Meetings Breakfast Symposium: Clinical Obstacles to Controlling Hyperphosphatemia. Health practitioners in nephrology from across the U.S. Dallas, TX, 2015 36. Endocrine Grand Rounds, Emory University. Invited Talk: Peering through the FGF23 looking glass. Faculty and fellows of the Division of Endocrinology, Emory University, Atlanta, GA, 2015. 37. Sanofi-Genzyme Medical Education Partners Program. Invited talk: Phosphorus metabolism in the modern diet. Boston, MA, 2015 38. Nephrology Grand Rounds, Drexel University. Invited talk: Phosphorus metabolism and the modern diet. Faculty, fellows and staff at Drexel University Division of Nephrology, Philadelphia, PA, 2015. 39. American Society of Nephrology, Annual National Meeting. Invited talk: FGF23 causes poor CKD and cardiac outcomes. Nephrologists and researchers from across the world. San Diego, CA, 2015 40. American Society of Nephrology, Annual National Meeting. Invited talk: Dietary phosphorus and kidney health. Nephrologists and researchers from across the world. San Diego, CA, 2015 41. National Kidney Foundation 2016 Spring Clinical Meetings Breakfast Symposium: Foundations for the Value of Phosphate Binders. Health practitioners in nephrology from across the U.S. Boston, MA 2016 42. American Society of Nephrology, Annual National Meeting. Invited talk: Contributions of Environment and Diet to Health Disparities in Chronic Kidney Disease. Nephrologists and researchers from across the world. Chicago, IL, 2016 43. Southern Society of Clinical Investigation Annual Meeting. State-of-the-art speaker: Diet and phosphorus metabolism in the modern era. New Orleans, LA, 2017 44. Medicine Grand Rounds, Massachusetts General Hospital: Obesity and chronic kidney disease: should we be worried? Boston, MA, 2017 45. Fibroblast growth factor 23: an interdisciplinary dialog for chronic kidney disease, NIDDK workshop. Invited talk: Dietary considerations for patients and trial participants. Bethesda, MD, 2017. 46. National Kidney Foundation 2017 Spring Clinical Meetings Breakfast Symposium: Physiology of iron metabolism. Health practitioners in nephrology from across the U.S. Orlando, FL 2017 47. China Boao Blood Purification Forum 2017. Invited talk: Fibroblast growth factor 23 in chronic kidney disease: an update. Nephrologists and surgeons from around China. Haikou, Hainan Province, China. 2017 48. Nephrology Grand Rounds, Northwestern University: APOL1 nephropathy risk variants are protective: wait, what? Chicago, IL, 2017. 49. American Society of Nephrology, Annual National Meeting. Invited talk: Analytical Methods: Observational Studies. Nephrologists and researchers from across the world. New Orleans, LA, 2017 50. Medicine Grand Rounds, University of Toledo: Fibroblast growth factor 23 as a mechanism of cardiorenal disease Toledo, OH, 2018. 51. Southern Society of Clinical Investigation Annual Meeting. State-of-the-art speaker: APOL1 and health disparities: beyond the kidney. New Orleans, LA, 2018 52. Nephrology Grand Rounds, Case Western Reserve University: Fostering translational research: the FGF23 story Cleveland, OH 2018 53. Renal Grand Rounds, University of California, Los Angeles: Phosphorus management in chronic kidney disease: what are we doing? Los Angeles, CA, 2018 54. Nephrology Grand Rounds, Harbor-UCLA Medical Center: Phosphorus management in chronic kidney disease: what are we doing? Los Angeles, CA, 2018 55. UCLA Combined Renal Grand Rounds, Wadsworth VA Medical Center: Phosphorus management in chronic kidney disease: what are we doing? Los Angeles, CA, 2018 56. Nephrology Grand Rounds, University of California, Irvine: APOL1 and health disparities: peering beyond the kidney. Irvine, CA, 2018 57. European Society of Veterinary and Comparative Nutrition, invited talk: Dietary phosphorus and kidney and cardiovascular health. Munich, Germany, 2018 58. American Society of Nephrology, Annual National Meeting. Invited talk: Clinical Perspectives on FGF23, Phosphate and Vitamin D. Nephrologists and researchers from across the world. San Diego, CA, 2018 59. American Society of Nephrology, Annual National Meeting. Invited talk: FGF23 as a Therapeutic Target in CKD-MBD. Nephrologists and researchers from across the world. San Diego, CA, 2018 60. American Society of Nephrology, Annual National Meeting. Invited talk: Iron Supplementation in Non-Dialysis CKD Patients: Impact on Anemia Management and CKD-MBD. Nephrologists and researchers from across the world. San Diego, CA, 2018 61. Office of Dietary Supplements, National Institutes of Health. Invited talk: Pleiotropic effects of dietary phosphorus: implications for health and disease. Rockville, MD, 2018 62. San Francisco Veterans Administration Medical Center Grand Rounds: Emerging therapeutics for cardiorenal syndrome: the FGF23 story. San Francisco, CA, 2019 63. UCSF Nephrology Grand Rounds: Phosphorus management in chronic kidney disease: what are we doing? San Francisco, CA, 2019 64. DCI Medical Director Meeting and Home Therapies Symposium, Invited Presentation: Phosphorus management in hemodialysis patients: what are we doing? Tucson, AZ, 2019 65. American Society of Nephrology, Annual National Meeting. Invited talk: New Insights About Assessment and Treatment of Kidney Disease. Session: Best of ASN Journals: CJASN and JASN. Nephrologists and researchers from across the world. Washington, DC, 2019 66. American Society of Nephrology, Annual National Meeting. Invited talk: APOL1 Variants in the General Population and Among Transplant Recipients. Session: APOL1: The Dawning of the Era of Treatment. Nephrologists and researchers from across the world. Washington, DC, 2019 67. American Society of Nephrology, Annual National Meeting. Invited talk: When Bone and Mineral Disease and Anemia Management Collide: Introduction. Nephrologists and researchers from across the world. Washington, DC, 2019 68. University of Miami Nephrology Grand Rounds: Vitamin D in the era of Fibroblast Growth Factor 23: is there still a role? Miami, FL 2020 69. Tufts Nephrology Grand Rounds: The old and new about dietary phosphorus consumption in the modern era. Virtual Presentation, 2020 70. Renal Round 2020, Invited talk: New scenarios in the treatment of secondary hyperparathyroidism. Nephrologists from Mexico (Collegio de Nefrologos de Mexico, A.C), Virtual presentation, 2020. GRANT SUPPORT: (CURRENT, PENDING, AND PAST) Active K24DK116180 (Gutirrez) 08/01/2018-07/31/2023 NIH/NIDDK Mentored patient-oriented research in disparities in cardiovascular and kidney disease The goal of this project is to provide the candidate protected time and resources to build a comprehensive training program for clinical investigators in patient-oriented research in health disparities in cardiovascular and kidney disease. R01HL144716 (D. Pollock [contact], Gutirrez MPI) 08/01/2019-07/31/2024 NIH/NHLBI Timing of sodium intake and nocturnal sodium excretion and blood pressure in obese African Americans. The overarching goals of this application are to determine how the time of day for salt intake impact blood pressure rhythms and urinary sodium excretion, and circadian timing of factors responsible for blood pressure regulation and cardiometabolic health in obese African American adults. U01 DK102730-01A1 (MPI: Gutirrez, Ix, Sarnak [contact], Shlipak) 08/20/2016-07/31/2021 NIH/NIDDK Beyond the glomerulus: novel clinical markers of kidney health and prognosis. The main goal of this grant is to examine the association of novel markers of tubular injury and function with kidney function decline, acute kidney injury and end-stage renal disease within the Multi-Ethnic Study of Atherosclerosis (MESA) and the Reasons for Geographic and Racial Differences in Stroke (REGARDS) cohorts. R25DK112731 (J. Pollock, Gutirrez MPI) 04/01/2019-03/31/2024 NIH/NIDDK PRedOctoral PhD and MD research training in Teams (PROmoTE) The overall goal of this proposal is to recruit and provide a curriculum to develop skills in kidney disease research, by immersing students in a novel program of team training and career development of PhD and MD students at UAB. UL1 TR003096 (Kimberly) 05/06/2019-04/30/2024 NIH/NCATS Center for Clinical and Translational Sciences (CCTS) The vision of the Center for Clinical and Translational Science (CCTS) Hub is to reduce health disparities in diseases disproportionately represented within the Deep South as we accelerate discovery to improve human health. Role: Deputy Director P30 DK079337 (Agarwal) 08/01/2018 07/31/2023 NIH/NIDDK UAB-UCSD OBrien core center for acute kidney injury research The main objective of this core center is to provide scientifically rigorous, state-of-the-art methodologies in a cost-effective manner to address experimental questions that will advance our understanding of the pathophysiology of acute kidney injury, enhance our diagnostic specificity and expand our therapeutic and preventive approaches for acute kidney injury, specifically in the intensive care unit and in the setting of kidney transplantation. Role: co-director of the Biostatistics core P30DK079331-12S1 (Gutierrez) 09/16/2019-12/31/2020 NIH/NIDDK Enhancing the capacity to examine the impact of acute kidney injury on disparities in chronic kidney disease outcomes in the Southeastern US. The main objective of this revision application is to examine the impact of acute kidney injury on disparities in chronic disease outcomes in the Southeastern US and conduct a pilot and feasibility study of an Acute Kidney Injury follow-up clinic. P30DK079331-13S1 (Agarwal, Gutierrez, Ix, Shlipak) 08/01/2020-07/31/2021 NIH/NIDDK Kidney Tubular Injury and Dysfunction and Racial Disparities in Incident Hypertension and Kidney Function Decline. The main objective of this revision application is to examine the association of plasma and urine biomarkers of kidney injury and dysfunction with the incidence of hypertension and rapid estimated glomerular filtration rate decline and racial disparities in these outcomes in participants of the Coronary Artery Risk Development in Young Adults (CARDIA) study. R21 NS111275 (King) 04/01/19 03/31/21 NIH/NINDS FGF23: a novel biomarker in ALS and more Amyotrophic lateral sclerosis is a fatal degenerative disease of motor neurons. There are currently no biomarkers that can predict prognosis or track progression of the disease. This proposal will investigate FGF23, a novel biomarker which may fill this clinical void and also provide insight into the pathophysiology of the disease. Role: co-investigator No number assigned (Gutirrez) 08/11/2017-08/10/2022 GlaxoSmithKline A Phase 3 Randomized, Open Label (Sponsor Blind), Active-Controlled, Parallel-Group, Multi-center, Event Drive Study in Non-Dialysis Subjects with Anemia Associated with Chronic Kidney Disease to Evaluate the Safety and Efficacy of Daprodustat Compared to Darbepoietin Alfa. Role: site PI No number assigned (Muntner) 07/01/2020-03/31/2021 Amgen, Inc. Lp(a) and risk for cardiovascular events by race/ethnicity among adults with chronic kidney disease in the Chronic Renal Insufficiency Cohort (CRIC) study. Compare the distribution of Lp(a) levels among adults with CKD by race/ethnicity (i.e., non-Hispanic black, non-Hispanic white or other). We hypothesize that Lp(a) levels will be higher among non-Hispanic blacks versus non-Hispanic whites and those of other race/ethnicity Completed R01 NS080850 (Gutirrez) 09/01/2012 07/31/2018 NCE NIH/NINDS Title: Impact of disordered mineral metabolism on stroke and cognitive impairment. The goal of this project is to prospectively examine the associations of vitamin D deficiency and excess fibroblast growth factor 23 concentrations with incident stroke and cognitive impairment in participants of the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study. R03 DK095005 (Gutirrez) 06/01/2012 - 05/30/2015 NIH/NIDDK Title: Phosphorus-based Food Additives, Mineral Metabolism and Cardiovascular Health. The goal of this project is to examine the impact of phosphorus-based food additives in commercially processed foods on mineral metabolism, inflammation, and vascular function in healthy volunteers. AHA 15SFDRN25620022 (Gutirrez) 07/01/15 06/30/2020 NCE Title: Impact of lowering phosphate additive intake on mineral metabolism and cardiovascular health in community-living adults. The goal of this project is to examine the impact of lowering the intake of phosphorus-based food additives on fibroblast growth factor 23 concentrations and measures of vascular health in community-dwelling adults. K23 DK081673 (Gutirrez) 08/1/2008 - 06/30/2013 NIH/NIDDK Racial Differences in Phosphorus Metabolism in Health and in Kidney Disease The goal of this project is to examine racial differences in the metabolism of phosphorus in health and chronic kidney disease in the effort to identify novel risk factors for racial disparities in cardiovascular and kidney disease progression. K23 DK114475 (Panwar) 07/01/2017-04/30/2022 NIH/NIDDK Novel regulators of fibroblast growth factor 23 in chronic kidney disease: iron deficiency and hypoxia. The goal of this project is to examine the role of iron deficiency and hypoxia in the etiology of elevated fibroblast growth factor 23 concentrations in individuals with chronic kidney disease. Role: primary mentor No number assigned (Arora, Gutirrez) 4/1/2019-3/31/2020 CCTS Interdisciplinary Network Pilot Program The Diurnal Rhythm in Natriuretic Peptide Levels and Relationship with Nocturnal Blood Pressure The main goal of this pilot and feasibility study is to examine diurnal rhythm in natriuretic peptide levels in healthy volunteers, whether this differs in obese vs. lean individuals, and if there are differences by race. No number assigned (Gutirrez) 08/01/2016-04/30/2019 Keryx Biopharmaceuticals (investigator initiated study) Impact of ferric citrate vs. ferrous sulfate on iron parameters and hemoglobin in individuals with moderate to severe chronic kidney disease with iron deficiency. The goal of this project is to compare the effect of ferric citrate vs. ferrous sulfate in increasing serum iron parameters and hemoglobin in individual with moderate to severe chronic kidney disease. No Number Assigned (Warnock) 12/22/2003 - 4/30/2013 Amgen Corporation Renal Ancillary Study of the REGARDS Study (Renal REGARDS) The objectives of this investigator-initiated study is to determine if anemia and chronic kidney disease are important variables that contribute to the incidence of new cerebrovascular events during the 5 years of follow-up of the REGARDS cohort. Role: co-investigator No Number Assigned (Gutirrez) 02/15/2012 02/14/2013 UAB Diabetes Research and Training Center Advanced glycation end-products, inflammation and insulin resistance in chronic kidney disease The objectives of this pilot/feasibility study are to examine the impact of diet-derived advanced glycation end-products on inflammation, insulin resistance and vascular reactivity in patients with chronic kidney disease. No Number Assigned (Gutirrez) 02/01/2015-08/30/2016 NRTC Anderson Innovation Grant Characterization of HDL subfractions by APOL1 risk status in African Americans The main goal of this project is to examine potential functional and structural differences in small HDL particles by APOL1 nephropathy risk status in African Americans. No Number Assigned (Gutirrez) 07/01/2006 06/30/2008 American Kidney Fund Clinical Scientist in Nephrology Fellowship Assessment of phosphorus intake and vitamin D deficiency in non-invasive measurements of cardiovascular disease in chronic kidney disease. The objective of this study was to examined the association of phosphorus intake and vitamin D with non-invasive measurements of cardiovascular disease in chronic kidney disease. BIBLIOGRAPHY: Manuscripts: Peer-Reviewed Original Research (* represents trainee) 1. Marcelino J, Carpten JD, Suwairi WM, Gutirrez OM, Schwartz S, Robbins C, Sood R, Makalowska I, Baxevanis A, Johnstone B, Laxer RM, Zemel L, Kim CA, Herd JK, Ihle J, Williams C, Johnson M, Raman V, Alonso LG, Brunoni D, Gerstein A, Papadopoulos N, Bahabri SA, Trent JM, Warman ML. CACP, Encoding a Secreted Proteoglycan, is Mutated in Camptodactyly-Arthropathy-Coxa Vara-Pericarditis Syndrome. Nature Genetics 1999; 23: 319-322. [PMID 10545950] 2. Gutirrez O, Isakova T, Rhee E, Holmes J, Collerone G, Jueppner H, Wolf M. Fibroblast Growth Factor 23 Mitigates Hyperphosphatemia but Accentuates Calcitriol Deficiency in Chronic Kidney Disease. J Am Soc Nephrol 2005; 16:2205-15. [PMID 15917335] 3. Bhan I, Shah A, Holmes J, Isakova T, Gutirrez O, Burnett SA, Jueppner H, Wolf M. Post-transplant hypophosphatemia: Tertiary Hyper-Phosphatoninism? Kidney Int 2006; 70:1486-94. [PMID 16941023] 4. Wolf M, Shah A, Gutirrez O, Ankers E, Monroy M, Tamez H, Steele D, Chang Y, Camargo CA, Tonelli M, Thadhani R. Vitamin D Levels and early mortality among incident hemodialysis patients. Kidney Int 2007 72:1004-13. [PMID 17687259] 5. Isakova T, Gutirrez O, Shah A, Castaldo L, Holmes J, Lee H, Wolf M. Postprandial Calcium and Phosphorus Metabolism in the Pathogenesis of Secondary Hyperparathyroidism in Early Chronic Kidney Disease. J Am Soc Nephrol 2008; 19:615-623. [PMID 18216315, PMC2391049] 6. Gutirrez OM, Isakova T, Andress D, Levin A, Wolf, M. Prevalence and Severity of Disordered Mineral Metabolism in Blacks with Chronic Kidney Disease. Kidney Int 2008; 73: 956-962. [PMID 18256597] 7. Wolf M, Betancourt J, Chang Y, Shah A, Teng M, Tamez H, Gutirrez O, Camargo CA, Melamed M, Norris K, Stampfer MJ, Powe NR, Thadhani R. Impact of Activated Vitamin D and Race on Survival among Hemodialysis Patients. J Am Soc Nephrol 2008; 19:1379-88. [PMID 18400938, PMC2440300] 8. Gutirrez OM, Tamez H, Bhan I, Zazra J, Tonelli M, Wolf M, Januzzi JL, Chang Y, Thadhani R. N-terminal pro-B-type Natriuretic Peptide Concentrations in Hemodialysis Patients: Prognostic Value of Baseline and Follow-up Measurements. Clin Chem 2008; 54: 1339-48. [PMID 18539645] 9. Gutirrez OM, Mannstadt M, Isakova T, Rauh-Hain JA, Tamez H, Shah A, Smith K, Lee H, Thadhani R, Jppner H, Wolf M. Fibroblast Growth Factor 23 and Mortality among Hemodialysis Patients. N Engl J Med 2008; 359:584-592. [PMID 18687639, PMC2890264] 10. Isakova T, Gutirrez OM, Chang Y, Shah A, Tamez H, Smith K, Thadhani R, Wolf M. Phosphorus Binders and Survival on Hemodialysis. J Am Soc Nephrol 2009;20:388-96. [PMID 19092121, PMC2637053] 11. Lee PS, Kartik S, Karumanchi SA, Tamez H, Bhan I, Isakova T, Gutirrez O, Wolf M, Chang Y, Stossel T, Thadhani R. Plasma Gelsolin, Circulating Actin, and Chronic Hemodialysis Mortality. J Am Soc Nephrol 2009; 20:1140-8. [PMID 19389844, PMC2678046] 12. Gutirrez OM, Januzzi JL, Isakova T, Laliberte K, Smith K, Collerone G, Sarwar A, Hoffmann U, Coglianese E, Christenson R, Wang TJ, DeFilippi C, Wolf M. Fibroblast Growth Factor 23 and Left Ventricular Hypertrophy in Chronic Kidney Disease. Circulation, 2009; 119:2545-2552. [PMID 19414634, PMC2740903] 13. Patel NM, Gutirrez OM, Andress DL, Coyne DW, Levin A, Wolf M. Vitamin D Deficiency and Anemia in Early Chronic Kidney Disease. Kidney Int Apr 2010; 77:715-20. [PMID 20130525] 14. Gutirrez OM, Isakova T, Smith K, Epstein M, Patel N, Wolf M. Racial Differences in Postprandial Mineral Ion Handling in Health and in Chronic Kidney Disease. Nephrol Dial Transplant 2010; 25(12):3970-7. [PMID 20530498, PMC3108369] 15. Gutirrez OM, Anderson C, Isakova T, Scialla J, Negrea L, Anderson AH, Bellovich K, Chen J, Robinson N, Ojo A, Lash J, Feldman HI, Wolf M. Low Socioeconomic Status Associates with Higher Serum Phosphate Irrespective of Race. J Am Soc Nephrol. 2010; 21: 1953-1960. [PMID 20847142, PMC3014009] 16. Isakova T, Gutirrez OM, Patel NM, Andress DL, Wolf M, Levin A. Vitamin D Deficiency, Inflammation and Albuminuria in Chronic Kidney Disease: Complex Interactions. J Renal Nutr. 2011; 21(4):295-302 [PMID 20817560] 17. Gutirrez OM, Isakova T, Enfield G, Wolf M. Impact of Poverty on Serum Phosphate Concentrations in the Third National Health and Nutrition Examination Survey. J Renal Nutr. 2011; 21(2): 140-8. [PMID 20537917, PMC293723] 18. Isakova T, Gutirrez OM, Smith K, Epstein M, Keating LK, Jppner H, Wolf M. Pilot Study of Dietary Phosphorus Restriction and Phosphorus Binders to Target Fibroblast Growth Factor 23 in Patients with Chronic Kidney Disease. Nephrol Dial Transplant 2011; 26(2): 584-91. [PMID 20631407, PMC3108359] 19. Gutirrez OM, Farwell WR, Kermah D, Taylor EN. Racial Differences in the Relationship Between Vitamin D, Bone Mineral Density and Parathyroid Hormone in the National Health and Nutrition Examination Survey. Osteoporosis Int. 2011; 22(6):1745-53. [PMID 20848081, PMC3093445] 20. Isakova T, Anderson CA, Leonard MB, Xie D, Gutirrez OM, Rosen LK, Theurer J, Bellovich K, Steigerwalt SP, Tang I, Anderson AH, Townsend RR, He J, Feldman HI, Wolf M. Diuretics, Calciuria and Secondary Hyperparathyroidism in the Chronic Renal Insufficiency Cohort. Nephrol Dial Transplant, 2011; 26(4):1258-1265. [PMID 21382989, PMC3108352] 21. Isakova T, Wahl P, Vargas G, Gutirrez OM, Scialla J, Xie H, Appleby D, Nessel L, Bellovich K, Chen J, Hamm L, Gadegbeku C, Horwitz E, Townsend RR, Anderson CA, Lash JP, Hsu C, Leonard MB, Wolf M. Fibroblast growth factor 23 is elevated before parathyroid hormone and phosphate in chronic kidney disease. Kidney Int., 2011; 79(12): 1370-8. [PMID 21389978, PMC3134393] 22. Carvalho C, Isakova T, Collerone G, Olbina G, Wolf M, Westerman M, Gutirrez OM. Hepcidin and Disordered Mineral Metabolism in Chronic Kidney Disease. Clin Nephrol, 2011; 76(2):90-8. [PMID 21762639] 23. Isakova T, Xie H, Yang W, Xie D, Anderson AH, Scialla J, Wahl P, Gutirrez OM, Steigerwalt S, He J, Schwartz S, Lo J, Ojo A, Sondheimer J, Hsu CY, Lash J, Leonard M, Kusek JW, Feldman HI, Wolf M. Fibroblast Growth Factor 23 and Risks of Mortality and End-Stage Renal Disease in Patients with Chronic Kidney Disease. JAMA 2011; 305(23):2432-2439. [PMID 21673295, PMC3124770]. 24. Faul C, Amaral AP, Oskouei B, Hu MC, Sloan A, Isakova T, Gutirrez OM, Aguillon-Prada R, Lincoln J, Hare JM, Mundel P, Morales A, Scialla J, Fischer M, Soliman EZ, Chen J, Go AS, Rosas SE, Nessel L, Townsend RR, Feldman HI, St. John Sutton M, Ojo A, Gadegbeku C, Di Marco GS, Reuter S, Kentrup D, Tiemann K, Brand M, Hill JA, Moe OW, Kuro-o M, Kusek JW, Keane MG, Wolf M. Fibroblast growth factor 23 induces left ventricular hypertrophy. J Clin Invest 2011;121(11):4393-408. [PMID 21985788, PMC3204831] 25. Bowling CB, Inker LA, Gutirrez OM, Allman RM, Warnock DG, McClellan W, Muntner P. Age-specific associations of reduced estimated glomerular filtration rate with concurrent chronic kidney disease complications. Clin J Am Soc Nephrol 2011; 6(12):2822-8. [PMID 22034504, PMC3255373] 26. Gutirrez OM, Wolf M, Taylor EN. Fibroblast growth factor 23, cardiovascular disease risk factors, and phosphorus intake in the Health Professionals Follow-Up Study. Clin J Am Soc Nephrol 2011; 6(12):2871-8. [PMID 22034506, PMC3255372]. 27. Rizk D, Gutirrez OM, Levitan EB, McClellan WB, Safford M, Soliman EZ, Warnock DG, Muntner P. Prevalence and prognosis of unrecognized myocardial infarctions in chronic kidney disease. Nephrol Dial Transplant 2012; 27(9):3482-8. [PMID 22167594, PMC3433770] 28. Houston J, Smith K, Isakova T, Sowden N, Wolf M, Gutirrez OM. Associations of Dietary Phosphorus Intake, Urinary Phosphate Excretion and Fibroblast Growth Factor 23 with Vascular Stiffness in Chronic Kidney Disease. J Renal Nutr 2013; 23(1):12-20 [PMID 22406119, PMC3378791] 29. Gutirrez OM, Katz R, Peralta CA, de Boer IH, Siscovick D, Wolf M, Diez Roux A, Kestenbaum B, Nettleton JA, Ix JH. Associations of Socioeconomic Status and Processed Food Intake with Serum Phosphorus in Community-Living Adults: the Multi-Ethnic Study of Atherosclerosis. J Renal Nutr 2012; 22(5):480-9. [PMID 22217539, PMC3321388] 30. Gutirrez OM, Smith KT, Barchi-Chung A, Patel NM, Isakova T, Wolf M. (1-34) parathyroid hormone infusion acutely lowers fibroblast growth factor 23 concentrations in adult volunteers. Clin J Am Soc Nephrol 2012; 7(1):139-45. [PMID: 22246283, PMC3265347] 31. Wahl P, Xie H, Scialla J, Anderson CA, Bellovich K, Brecklin C, Chen J, Feldman H, Gutirrez OM, Lash J, Leonard MB, Negrea L, Rosas S, Anderson AH, Townsend RR, Wolf M, Isakova T. Earlier onset and greater severity of disordered mineral metabolism in diabetic patients with chronic kidney disease. Diabetes Care 2012; 35(5):994-1001. [PMID:22446176, PMC3329844] 32. Nielsen SE, Reinhard H, Zdunek D, Hess G, Gutirrez OM, Wolf M, Parving HH, Jacobsen PK, Rossing P. Tubular markers are associated with decline in kidney function in proteinuric type 2 diabetic patients. Diabetes Res Clin Pract. 2012; 97(1):71-6. [PMID 22402396] 33. Bell EK, Gao L, Judd S, Glasser SP, McClellan W, Gutirrez OM, Safford M, Lackland DT, Warnock DG, Muntner P. Blood pressure indices and end-stage renal disease risk in adults with chronic kidney disease. Am J Hypertens. 2012; 25(7):789-96. [PMID: 22573012, PMC 3784349]. 34. Gutirrez OM, Judd SE, Muntner P, Rizk DV, McClellan WM, Safford MM, Cushman M, Kissela BM, Howard VJ, Warnock DG. Racial differences in albuminuria, kidney function and risk of stroke. Neurology. 2012; 79(16):1686-92 [PMID: 22993285, PMC3468778] 35. Alvarez JA, Law J, Coakley K, Zughaier S, Wassie H, Gutirrez OM, Ziegler TR, Tangpricha V. High-dose cholecalciferol reduces parathyroid hormone in patients with early chronic kidney disease: a pilot, randomized, double-blind, placebo-controlled trial. Am J Clin Nutr 2012; 96(3):672-9. [PMID: 22854402, PMC3417221]. 36. Smith K, de Filippi C, Isakova T, Gutirrez OM, Laliberte K, Seliger S, Kelley W, Duh S, Hise M, Christenson R, Wolf M, Januzzi J. Fibroblast growth factor 23, high-sensitivity cardiac troponin and left ventricular hypertrophy in chronic kidney disease. Am J Kidney Dis 2013; 61(1): 67-73 [PMID 22883134] [PMC3525738]. 37. Gutirrez OM, Sun CC, Chen W, Babitt JL, Lin HY. Statement of concern about a commercial assay used to measure soluble hemojuvelin in humans. Am J Nephrol 2012; 36(4):332-333. [PMID 23006450] 38. Hanks LJ, Newton AL, Ashraf AP, Gutirrez OM, Casazza K. Reduced-carbohydrate, weight loss diet is associated with greater bone mineral content in obese African-American girls. J Diabetes Res Clin Metab 2012; 1:9. 39. Tanner RM, Gutirrez OM, Judd S, McClellan W, Bowling CB, Bradbury B, Safford MM, Cushman M, Warnock D, Muntner P. Geographic variation in chronic kidney disease prevalence and end stage renal disease incidence in the United States: results from the REGARDS study. Am J Kidney Dis 2012; 61(3): 395-403 [PMID 23228944] [PMC3659181]. 40. Tuot DS, Plantinga LC, Judd SE, Muntner P, Hsu CY, Warnock DG, Gutirrez OM, Safford M, Powe NR, McClellan MM. Healthy behaviors, risk factor control and awareness of chronic kidney disease. Am J Nephrol 2013; 37(2):135-143 [PMID 23392070] [PMC3649001]. 41. Isakova T, Barchi-Chung A, Enfield G, Smith K, Vargas G, Houston J, Xie H, Wahl P, Schiavenato E, Dosch A, Gutirrez OM, Diego J, Lenz O, Contreras G, Mendez A, Weiner RB, Wolf M. Effects of dietary phosphate restriction and phosphate binders on FGF23 levels in CKD. Clin J Am Soc Nephrol 2013;8(6):1009-18. [PMID 23471131] [PMC3675851] 42. Muntner P, Judd SE, Gao L, Gutirrez OM, Rizk DV, McClellan W, Cushman M, Warnock DG. Cardiovascular risk factors and end-stage renal disease and mortality risk. J Am Soc Nephrol 2013; 24(7):1159-65. [PMC3699822] 43. Tanner RM, Calhoun DA, Bell EK, Bowling CB, Gutirrez OM, Irvin MR, Lackland DT, Oparil S, Warnock D, Muntner P. Prevalence of apparent treatment-resistant hypertension among individuals with CKD. Clin J Am Soc Nephrol 2013; 8(9):1583-90. [PMID 23868902][PMC3805064] 44. Baber U, Gutirrez OM, Levitan E, Warnock DG, Farkouh M, Tonelli M, Safford M, Muntner P. Risk for recurrent coronary heart disease and all-cause mortality among individuals with chronic kidney disease compared with diabetes mellitus, metabolic syndrome, and cigarette smokers. Am Heart J 2013; 166(2):373-380. [PMID 23895822] 45. Gutirrez OM, Khodneva YA, Muntner P, Rizk DV, McClellan WM, Cushman M, Warnock DG, Safford MM. Association between urinary albumin excretion and coronary heart disease in black versus white adults. JAMA 2013; 310(7):706-713. [PMID 23989654] [PMC3837520] 46. Hanks LJ*, Tanner RM, Muntner P, Kramer H, McClellan WM, Warnock DG, Judd SE, Gutirrez OM. Metabolic subtypes and risk of mortality in normal weight, overweight and obese individuals with CKD. Clin J Am Soc Nephrol 2013; 8(12): 2064-71. [PMID 24178980] [PMC3848389]. 47. Carrigan A*, Klinger A, Choquette SS, Luzuriaga-McPherson A, Bell EK, Darnell B, Gutirrez OM. Contribution of food additives to sodium and phosphorus content of diets rich in processed foods. J Renal Nutr. 2014; 24(1):13-19. [PMID 24355818] [NIHMSID 524831][PMC3869975] 48. Judd SE, Gutirrez OM, Newby PK, Howard G, Howard VJ, Locher JL, Kissela BM, Shikany JM. Dietary patterns are associated with incident stroke and contribute to excess risk of stroke in Black Americans. Stroke 2013; 44(1):3305-11. [PMID 24159061] [PMC3898713] 49. Chang AR, Lazo M, Appel LJ, Gutirrez OM, Grams ME. High dietary phosphorus intake is associated with all-cause mortality: results from NHANES III. Am J Clin Nutr. 2013; 99(2):320-7. [PMC3893724]. 50. Tanner RM, Calhoun DA, Bell EK, Bowling CB, Gutirrez OM, Irvin MR, Lackland DT, Oparil S, McClellan W, Warnock DG, Muntner P. Incident ESRD and treatment-resistant hypertension: the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study. Am J Kidney Dis. 2014; 63(5):781-8. [PMC4141647] 51. Gutirrez OM, Muntner P, Rizk DV, McClellan WM, Warnock DG, Newby PK, Judd SE. Dietary patterns and risk of death and progression to ESRD in individuals with CKD: a cohort study. Am J Kidney Dis. 2014; 64(2):204-13. [PMC4111976] 52. Cushman M, Judd SE, Howard VJ, Kissela B, Gutirrez OM, Jenny NS, Ahmed A, Thacker EL, Zakai NA. N-terminal pro-B-type natriuretic peptide and stroke risk: the REasons for Geographic and Racial Differences in Stroke cohort. Stroke. 2014; 45(6):1646-50 [PMID 24757103]. 53. Bowling CB, Booth JN, Gutirrez OM, Kurella Tamura M, Huang L, Kilgore M, Judd S, Warnock DG, McClellan W, Allman RM, Muntner P. Nondisease-specific problems and all-cause mortality among older adults with CKD: The REGARDS study. Clin J Am Soc Nephrol. 2014; 9(10):1737-45. [PMC4186504] 54. Hanks LJ*, Casazza K, Ashraf AP, Wallace S, Gutirrez OM. Fibroblast growth factor 21, body composition, and insulin resistance in pre-pubertal and early pubertal males and females. Clin Endocrinol (Oxf.); 2015;82(4):550-6. [PMID 25039824] [PMC4289452] 55. Colantonio LD, Baber U, Banach M, Tanner RM, Warnock DG, Gutirrez OM, Safford MM, Wanner C, Howard G, Muntner P. Contrasting the KDIGO and the ACC/AHA cholesterol management guidelines for initiation of statin therapy for adults with chronic kidney disease. J Am Soc Nephrol. 2015; 26(5):1173-80. [PMID 25395432] [PMC 4413767] 56. Muntner P, Gutirrez OM, Zhao H, Fox CS, Wright NC, Curtis JR, McClellan W, Wang H, Kilgore M, Warnock DG, Bowling CB. Validation study of Medicare claims to identify older adults with CKD using the REasons for Geographic and Racial Differences in Stroke (REGARDS) Study. Am J Kidney Dis. 2015; 65(2):249-58. PMID 25242367 [PMC25242367] 57. Fedewa SA, McClellan WM, Judd SE, Gutirrez OM, Crews DC. The association between race and income on risk of mortality in patients with moderate chronic kidney disease. BMC Nephrol. 2014; 15(1):136. [PMC4144698] 58. Panwar B*, Hanks LJ, Tanner RM, Muntner P, Kramer H, McClellan WM, Warnock DG, Judd SE, Gutirrez OM. Obesity, metabolic health and risk of end-stage renal disease. Kidney Int. 2015; 87(6):1216-22. [PMC4449828] 59. Crews DC, Gutirrez OM, Fedewa SA, Luthi JC, Shoham D, Judd S, Powe NR, McClellan WM. Low Income, Community Poverty and Risk of End Stage Renal Disease. BMC Nephrol. 2014; 15(1):192. [PMC4269852] 60. Panwar B*, Jenny NS, Howard VJ, Wadley WG, Muntner P, Kissela BM, Judd SE, Gutirrez OM. Fibroblast growth factor 23 and risk of incident stroke in community-dwelling adults. Stroke 2015; 46(2):322-8. PMID 25563643 NIHMS647876 [PMC4308535] 61. Patel SJ, Hanks LJ, Ashraf AP, Gutirrez OM, Casazza K. Effects of 8 week resistance training on lipid profile and insulin levels in overweight/obese peri-pubertal boys. J Diab Res Clin Metab. 2015; 4:2. 62. Hanks LJ*, Gutirrez OM, Bamman MM, Ashraf A, McCormick KL, Casazza K. Circulating levels of fibroblast growth factor-21 increase with age independently of body composition differences among healthy individuals. J Clin Trans Endocrinol. 2015; 2(2):77-82. [PMID 26042208] [PMC4450097] 63. Hanks LJ*, Gutirrez OM, Ashraf A, Casazza K. Bone mineral content as a driver of energy expenditure in prepubertal boys. J Pediatr. 2015; 166(6):1397-403. [PMC4446221] 64. Hanks LJ*, Casazza K, Judd SE, Jenny NS, Gutirrez OM. Associations of fibroblast growth factor 23 with markers of inflammation, insulin resistance and obesity in adults. PLoS One 2015; 10(3). [PMC4374938] 65. Powell TC, Donnelly JP, Gutirrez OM, Griffin RL, Safford MM, Wang HE. Cystatin C and long term risk of community-acquired sepsis: a population-based cohort study. BMC Nephrol. 2015; 16(1):61. [PMC4413986] 66. Gutirrez OM, Judd SE, Irvin MR, Zhi D, Limdi N, Palmer ND, Rich SS, Sale MM, Freedman BI. APOL1 nephropathy risk variants are associated with altered high-density lipoprotein profiles in African Americans. Nephrol Dial Transplant 2016; 31:602-608. [PMID 26152403] [PMC 4805128] 67. Bentley AR, Divers J, Shriner D, Doumatey AP, Gutirrez OM, Adeyemo AA, Freedman BI, Rotimi CN. APOL1 G1 genotype modifies the association between HDLC and kidney function in African Americans. BMC Genomics 2015; 16:421. [PMC4448293] 68. Kramer H, Gutirrez OM, Judd SE, Muntner P, Warnock DG, Tanner RM, Panwar B, Shoham DA, McClellan W. Waist circumference, body mass index, and end-stage renal disease in the REGARDS (REasons for Geographic and Racial Differences in Stroke) Study. Am J Kidney Dis. 2016; 67(1):62-9 [PMID 26187471] 69. Gutirrez OM, Judd SE, Voeks JH, Carson AP, Safford MM, Shikany JM, Wang HE. Diet patterns and risk of sepsis in community-dwelling adults: a cohort study. BMC Infect Dis. 2015; 15:231. [PMID 26072206] PMC4465736 70. Colantonio LD, Tanner RM, Warnock DG, Gutirrez OM, Judd S, Muntner P, Bowling CB. The role of cystatin-C in the confirmation of reduced glomerular filtration rate among the oldest old. Arch Med Sci. 2016; 12(1):55-67. PMC4754366 71. Judd SE, Morgan CJ, Panwar B, Howard VJ, Wadley VG, Jenny NS, Kissela BM, Gutirrez OM. Vitamin D deficiency and incident stroke risk in community-living black and white adults. Int J Stroke. 2016; 11(1):93-102. PMID: 26763025; PMC4920062 72. Gutirrez OM, Luzuriaga-McPherson A, Lin Y, Gilbert LC, Ha SW, Beck GR Jr. Impact of phosphorus-based food additives on bone and mineral metabolism. J Clin Endocrinol Metab 2015; 100(11):4264-71. PMID 26323022. PMC4702463 73. Ilori TO, Ro YS, Kong SY, Gutirrez OM, Ojo AO, Jedd SE, Narayan KMV, Goodman M, Plantinga L, McClellan W. Oxidative balance score and chronic kidney disease. Am J Nephrol. 2015; 42:320-327. PMID 26569393 PMC4689189 74. Wang HE, Powell TC, Gutirrez OM, Griffin R, Safford MM. Pre-hospitalization risk factors for acute kidney injury during hospitalization for serious infections in the REGARDS cohort. Nephron Extra 2015; 5(3):87-99. PMC4677710 75. Tanner RM, Woodward M, Peralta C, Warnock DG, Gutirrez O, Shimbo D, Kramer H, Katz R, Muntner P. Validation of an Albuminuria Self-assessment Tool in the Multi-Ethnic Study of Atherosclerosis (MESA). Ethn Dis. 2015; 25(4):427-434. PMC4671433 76. Gutirrez OM, Parsa A, Isakova T, Scialla JJ, Chen J, Flack JM, Nessel LC, Gupta J, Bellovich KA, Steigerwalt S, Sondheimer JH, Wright JT, Feldman HI, Kusek JW, Lash JP, Wolf M. Genetic African ancestry and markers of mineral metabolism in chronic kidney disease: findings from the CRIC Study. Clin J Am Soc Nephrol. 2016; 11(4): 653-662. PMID 26912553 PMC4822668 77. Bowling CB, Bromfield SG, Colantonio LD, Gutirrez OM, Shimbo D, Reynolds K, Wright NC, Curtis JR, Judd SE, Franch H, Warnock DG, McClellan W, Muntner P. Association of reduced glomerular filtration rate and albuminuria with serious fall injuries among older adults: findings from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study. Clin J Am Soc Nephrol 2016; 11(7): 1236-43. PMID:27091516 PMC4934847 78. Palmer ND, Divers J, Lu L, Register TC, Carr JJ, Hicks PJ, Smith SC, Xu J, Judd SE, Irvin MR, Gutirrez OM, Bowden DW, Wagenknecht LE, Langefeld CD, Freedman BI. Admixture mapping of serum vitamin D and parathyroid hormone concentrations in the African American-Diabetes Heart Study. Bone. 2016; 87:71-7. PMID: 27032714 PMC4862915 79. Rostand SG, McClure LA, Kent ST, Judd SE, Gutirrez OM. Blood pressure, sunlight, and vitamin D. J Hyperten. 2016; 34(9):1704-10 PMID: 27379541 80. Panwar B*, Judd SE, Warnock DG, McClellan WM, Booth JN, Muntner P, Gutirrez OM. Hemoglobin concentration and risk of incident stroke in community-living adults. Stroke 2016; 47(8):2017-24. NIHMSID 794264 PMC4961542 81. Jackson JL*, Judd SE, Panwar B, Howard VJ, Wadley VG, Jenny NS, Gutirrez OM. Associations of 25-hydroxyvitamin D with markers of inflammation, insulin resistance and obesity in black and white community-dwelling adults. J Clin Trans Endocrinol. 2016; 5:21-25. NIHMSID 797058 PMC5098550 82. Ku E, Gassman J, Appel LJ, Smogorzewski M, Sarnak MJ, Glidden DV, Bakris G, Gutirrez OM, Hebert LE, Ix JH, Lea J, Lipkowitz MS, Norris K, Ploth D, Pogue VA, Rostand SG, Siew ED, Sika M, Tisher CC, Toto R, Wright Jr JT, Wyatt C, Hsu CY. BP control and long-term risk of ESRD and mortality. J Am Soc Nephrol 2017; 28(2):617-677. PMID: 27516235. PMC5280023 83. Deo R, Khodneva YA, Shlipak MG, Soliman EZ, Judd SE, McClellan WM, Brown TM, Rhodes JD, Gutirrez OM, Shah SJ, Albert CM, Safford MM. Albuminuria, Kidney Function and Sudden Cardiac Death: Findings from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study. Heart Rhythm. 2017; 14(1):65-71. PMID: 27523775. PMC5256547 84. Panwar B*, Judd SE, Howard VJ, Jenny NS, Wadley VG, Gutirrez OM. Vitamin D, Fibroblast Growth Factor 23 and Incident Cognitive Impairment: Findings from the REGARDS Study. PLoS One 2016; 11(11):e0165671. PMID 27812184 PMC5094718 85. Drew DA, Katz R, Kritchevsky S, Ix J, Shlipak M, Gutirrez OM, Newman A, Hoofnagle A, Fried L, Semba RD, Sarnak M. Association between Soluble Klotho and Change in Kidney Function: The Health Aging and Body Composition Study. J Am Soc Nephrol. 2017; [Epub ahead of print]. PMID 28104822 86. Naik RP, Irvin MR, Judd S, Gutirrez OM, Zakai NA, Derebail VK, Peralta C, Lewis MR, Zhi D, Arnett D, McClellan W, Wilson JG, Reiner AP, Kopp Jeffery B, Winkler CA, Cushman M. Sickle cell trait and end-stage renal disease in African Americans. J Am Soc Nephrol. 2017; [Epub ahead of print]. PMID: 28280138. 87. Garimella PS, Katz R, Ix JH, Fried L, Kritchevsky SB, Devarajan P, Bennett MR, Parikh CR, Shlipak MG, Harris TB, Gutirrez OM, Sarnak MJ. Association of Urinary Uromodulin with Kidney Function Decline and Mortality: the Health ABC Study. Clin Neph 2017; [Epub ahead of print]. PMID: 28332475 88. Ilori TO, Wang X, Huang M, Gutirrez OM, Narayan KM, Goodman M, McClellan W, Plantinga L, Ojo AO. Oxidative balance score and the risk of end-stage renal disease and cardiovascular disease. Am J Nephrol. 2017; 45(4):338-345. PMID: 28285313 89. Chen TK, Estrella MM, Vittinghoff E, Lin F, Gutirrez OM, Kramer H, Lewis CE, Kopp JB, Allen NB, Winkler CA, Bibbins-Domingo KB, Peralta CA. APOL1 genetic variants and longitudinal blood pressure in young adults. Kidney Int. 2017; [Epub ahead of print]. PMID: 28545715, PMC5610603 90. Thomas B,Matsushita K,Abate KH,Al-Aly Z,rnlv J,Asayama K,Atkins R,Badawi A,Ballew SH,Banerjee A,Barregrd L,Barrett-Connor E,Basu S,Bello AK,Bensenor I,Bergstrom J,Bikbov B,Blosser C,Brenner H,Carrero JJ,Chadban S,Cirillo M,Cortinovis M,Courville K,Dandona L,Dandona R,Estep K,Fernandes J,Fischer F,Fox C,Gansevoort RT,Gona PN,Gutirrez OM,Hamidi S,Hanson SW,Himmelfarb J,Jassal SK,Jee SH,Jha V,Jimenez-Corona A,Jonas JB,Kengne AP,Khader Y,Khang YH,Kim YJ,Klein B,Klein R,Kokubo Y,Kolte D,Lee K,Levey AS,Li Y,Lotufo P,El Razek HMA,Mendoza W,Metoki H,Mok Y,Muraki I,Muntner PM,Noda H,Ohkubo T,Ortiz A,Perico N,Polkinghorne K,Al-Radaddi R,Remuzzi G,Roth G,Rothenbacher D,Satoh M,Saum KU,Sawhney M,Schttker B,Shankar A,Shlipak M,Silva DAS,Toyoshima H,Ukwaja K,Umesawa M,Vollset SE,Warnock DG,Werdecker A,Yamagishi K,Yano Y,Yonemoto N,Zaki MES,Naghavi M,Forouzanfar MH,Murray CJL,Coresh J,Vos T; Global Burden of Disease 2013 GFR Collaborators, CKD Prognosis Consortium, and Global Burden of Disease Genitourinary Expert Group. J Am Soc Nephrol. 2017; [Epub ahead of print]. PMID: 28408440 91. Lang J, Katz R, Ix JH, Gutirrez OM, Peralta C, Parikh C, Saterfield S, Petrovic S, Devarajan P, Bennett M, Fried L, Cummings SR, Sarnak M, Shlipak M. Association of serum albumin levels with kidney function decline and incident chronic kidney disease in elders. Nephrol Dial Transplant. 2017; [Epub ahead of print]; PMID: 28992097 92. Park M, Katz R, Shlipak MG, Weiner D, Tracy R, Jotwani V, Hughes-Austin J, Gabbai F, Hsu CY, Pfeffer M, Bansal N, Bostom A, Gutirrez O, Sarnak M, Levey A, Ix JH. Urinary markers of fibrosis and risk of cardiovascular events and death in kidney transplant recipients: the FAVORIT trial. Am J Transplant 2017; [Epub ahead of print]; PMID: 28371433 93. Gutirrez OM, Limou S, Lin F, Peralta CA, Kramer HJ, Carr JJ, Bibbins-Domingo K, Winkler CA, Lewis CE, Kopp JB. APOL1 nephropathy risk variants do not associate with subclinical atherosclerosis or left ventricular mass in middle-aged black adults. Kidney Int. 2018; 93:727-732. PMC5826778. 94. Bajaj NS, Gutirrez OM, Arora G, Judd SE, Patel N, Bennett A, Prabhu SD, Howard G, Howard VJ, Cushman M, Arora P. Racial differences in plasma NT-proBNP levels and all-cause mortality: the REGARDS study. JAMA Cardiology 2018; 3(1):11-17. PMID 29167879 95. Chen TK, Katz R, Estrella MM, Gutirrez OM, Kramer H, Post WS, Shlipak MG, Wassel CL, Peralta CA. Association between APOL1 genotypes and risk of cardiovascular disease in the Multi-Ethnic Study of Atherosclerosis (MESA). J Am Heart Assoc. 2017; 6(12). PMID 29269352. 96. Walther CP, Gutirrez OM, Cushman M, Judd SE, Lang J, McClellan W, Muntner P, Sarnak MJ, Shlipak MG, Warnock DG, Ix JH. Serum albumin concentration and risk of ESRD: the REGARDS Study. Nephrol Dial Transplant 2018; 33(10):1770-1777 . PMID: 29281114. 97. Panwar B, Judd SE, Wadley VG, Jenny NS, Howard VJ, Safford MM, Gutirrez OM. Association of fibroblast growth factor 23 with risk of incident coronary heart disease in community-living adults. JAMA Cardiol. 2018; 3(4):318-325. PMID:29516098; PMC:5875372. 98. Panwar B, McCann D, Olbina G, Westerman M, Gutirrez OM. Effect of calcitriol on serum hepcidin in individuals with chronic kidney disease: a randomized controlled trial. BMC Nephrol 2018; 19(1):35. PMID: 29426300. PMC5807766 99. Drew DA, Katz R, Kritchevsky S, Ix J, Shlipak M, Newman A, Hoofnagle A, Fried L, Sarnak M, Gutirrez OM. Fibroblast growth factor 23: a biomarker of kidney function decline. Am J Nephrol. 2018; 47(4):242-250. PMID 29621752 100. Jotwani V, Katz R, Ix JH, Gutirrez OM, Bennett M, Parikh CR, Cummings SR, Sarnak MJ, Shlipak MG. Urinary biomarkers of kidney tubular damage and risk of cardiovascular disease and morality in elders. Am J Kidney Dis. 2018; 72(2):205-213. PMID 29602632, PMC6057830 101. Gutirrez OM, Irvin MR, Chaudhary NS, Cushman M, Zakai NA, David VA, Limou S, Pamir N, Reiner AP, Naik RP, Sale MM, Safford MM, Hyacinth HI, Judd SE, Kopp JB, Winkler CA. APOL1 nephropathy risk variants and incident cardiovascular disease events in community-dwelling Black adults. Circ Genom Precis Med 2018; [Epub ahead of print]. PMID 29899045 102. Selamet U, Katz R, Ginsberg C, Rifkin DE, Fried L, Kritchevsky S, Hoofnagle AN, Bibbins-Domingo K, Drew DA, Harris TB, Newman AB, Gutirrez OM, Sarnak MJ, Shlipak MG, Ix JH. Serum Calcitriol Concentrations and Kidney Function Decline, Heart Failure, and Mortality in Elderly Community-Living Adults: The Health, Aging and Body Composition Study. Am J Kidney Dis. 2018; 72(3):419-428. PMID 29889525 103. Akhabue E, Montag S, Reis JP, Pool LR, Mehta R, Yancy CW, Zhao L, Wolf M, Gutirrez OM, Carnethon MR, Isakova T. FGF23 (Fibroblast Growth Factor-23) and Incident Hypertension in Young and Middle-Aged Adults: the CARDIA Study (Coronary Artery Risk Development in Young Adults). Hypertension. 2018; 72(1):70-76. PMID: 29712737, PMC6002950 104. Zhao X, Geng X, Srinivasasainagendra V, Chaudhary N, Judd S, Wadley V, Gutirrez OM, Wang H, Lange EM, Lange LA, Woo D, Unverzagt F, Safford M, Cushman M, Limdi N, Quarells R, Arnett DK, Irvin MR, Zhi D. A PheWAS study of a large observational epidemiological cohort of African Americans: the REGARDS Study. BMC Genomics 2019; 12(Suppl 1):26. PMID 30704471; PMC6357353 105. Inker LA, Grams ME, Levey AS, Coresh J, Cirillo M, Collins JF, Gansevoort RT, Gutirrez OM, Hamano T, Heine GH, Ishikawa S, Jee SH, Kronenberg F, Landray MJ, Miura K, Nadkarni GN, Peralta CA, Rothenbacher D, Schaeffner E, Sedaghat S, Shlipak M, Zhang L, van Zuilen AD, Hallan SI, Kovesdy CP, Woodward M, Levin A. Relationship of eGFR and Albuminuria to Concurrent Laboratory Abnormalities: An Individual Participant Data Meta-Analysis in a Global Consortium. Am J Kidney Dis. 2019; 73(2):206-217. PMID 30348535; PMC6348050 106. Gray MS, Wang HE, Martin KD, Donnelly JP, Gutirrez OM, Shikany JM, Judd SE. Adherence to Mediterranean-style diet and risk of sepsis in the Reason for Geographic and Racial Differences in Stroke (REGARDS) Cohort. Br J Nutr. 2018; 120(12):1415-1421. PMID 30375291. PMC6753832 107. Kempker JA, Panwar B, Judd SE, Jenny NS, Wang HE, Gutirrez OM. Plasma 25-hydroxyvitamin D and risk of sepsis in the REGARDS cohort. Clin Infect Dis. 2019; 68(11):1926-1931. PMID 30239610. PMC6522683 108. Gray MS, Lakkur S, Howard VJ, Pearson K, Shikany JM, Safford M, Gutirrez OM, Colabianchi N, Judd SE. The association between residence in a food desert census track and adherence to dietary patterns in the REGARDS cohort. Food Public Health. 2018; 8(4):79-85. PMID 31467800 PMC6714990 109. Marks KJ, Hartman TJ, Judd SE, Ilori TO, Cheung KL, Warnock DG, Gutirrez OM, Goodman M, Cushman M, McClellan WM. Dietary oxidative balance scores and biomarkers of inflammation among individuals with and without chronic kidney disease. Nephron Extra. 2018;8(2):11-23. PMC6158582 110. Chang AR, Grams M, Ballew SH, Bilo H, Correa A, Evans M, Gutirrez OM, Hosseinpanah F, Iseki K, Kenealy T, Klein B, Kronenberg F, Lee BJ, Li Y, Miura K, Navaneethan SD, Roderick PJ, Valdivielso JM, Visseren FLJ, Zhang L, Gansevoort RT, Hallan SI, Levey AS, Matsushita K, Shalev V, Woodward M. Adiposity and the risk of glomerular filtration rate decline: results from a global consortium including over 5 million subjects. BMJ 2019; 364:k5301 PMID 30630856 PMC6481269. 111. Eaton EF, Tamhane A, Davy-Mendez T, Moore RD, Matthews WC, Saag MS, Mugavero MJ, Wyatt CM, Gutirrez OM. Kidney dysfunction does not contribute significantly to antiretroviral therapy (ART) modification in Treatment Nave PLWH receiving initial ART. J Acquir Immune Defic Syndr. 2019; 1:81(1):e6-e9; PMID 30865178 PMC6456383 112. Lara KM, Levitan EB, Gutirrez OM, Shikany JM, Safford MM, Judd SE, Rosenson RS. Dietary patterns and incident heart failure in adults with no known coronary disease. J Am Coll Cardiol. 2019; 73(16):2036-2045. PMID 31023426, PMC6501554 113. Bailey LN*, Levitan EB, Judd SE, Sterling MR, Goyal P, Cushman ME, Safford MM, Gutirrez OM. Association of urine albumin excretion with incident heart failure hospitalization in community-dwelling adults. JACC Heart Fail.2019 May;7(5):394-401.doi: 10.1016/j.jchf.2019.01.016.PubMed PMID: 31047019; PubMed Central PMCID: PMC6544368 114. Patel N, Gutirrez OM, Arora G, Howard G, Howard VJ, Judd SE, Prabhu SD, Levitan EB, Cushman M, Arora P. Race-based demographic, anthropometric, and clinical correlates of N-terminal pro-B-type natriuretic peptide. Int J Cardiol. 2019; 286:145-151. PMID 30878238 115. Gutirrez OM, Irvin MR, Zakai NA, Naik RP, Chaudhary NS, Estrella MM, Limou S, Judd SE, Cushman M, Kopp JB, Winkler CA. APOL1 nephropathy risk alleles and mortality in African-American adults: a cohort study. Am J Kidney Dis.2020 Jan;75(1):54-60.doi: 10.1053/j.ajkd.2019.05.027.Epub 2019 Sep 26.PubMed PMID: 31563468; PubMed Central PMCID: PMC7008402 116. Patel N, Cushman M, Gutirrez OM, Howard G, Safford MM, Muntner P, Durant RW, Prabhu SD, Arora G, Levitan EB, Arora P. Racial differences in the association of NT-proBNP with risk of incident heart failure in REGARDS. JCI Insight. 2019 Jun 4;5. PMID 31162140, PMC6629159 117. Grams ME, Surapeneni A, Ballew S, Appel L, Boerwinkle E, Boulware LE, Chen T, Coresh J , Cushman M, Gutirrez OM, Irvin MR, Ix J, Kopp J, Kuller L, Lipkowitz M, Mukamal K, Musani S, Naik R, Pajewski N, Peralta CA, Tin A, Wassel C, Wilson J, Winkler C, Young B, Zakai NA, Freedman BI. APOL1 kidney-risk variants and cardiovascular disease: an individual participant meta-analysis. J Am Soc Nephrol. 2019; 30(10):2027-2036. PMID: 31383730, PMC6779370 118. Paul S*, Judd SE, Howard VJ, Safford MM, Gutirrez OM. Association of 25-hydroxyvitamin D with incident coronary heart disease in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study. Am Heart J. 2019; 217:140-147. PMID 31629964, PMC6861690. 119. Chaudhary NS, Moore JX, Zakai NA, Judd SE, Naik RP, Limou S, Cushman M, Lange LA, Wang HE, Winkler CA, Irvin MR, Kopp JB, Gutierrez OM. APOL1 nephropathy risk alleles and risk of sepsis in African Americans. Clin J Am Soc Nephrol. 2019;14(12):1733-1740. contributed equally PMID 31704668; PMC6895473 120. Patel N, Russell GK, Musunuru K, Gutierrez OM, Halade G, Kain V, Prabhu SD, Margulies KB, Cappola TP, Arora G, Wang TJ, Arora P. Race, Natriuretic Peptides, and High-Carbohydrate Challenge: A Clinical Trial.Circ Res.2019 Nov 8;125(11):957-968.doi: 10.1161/CIRCRESAHA.119.315026.Epub 2019 Oct 6.PubMed PMID: 31588864; PubMed Central PMCID: PMC7033629. 121. Pool LR, Kershaw KN, Montag SE, Gorden-Larsen P, Gutirrez OM, Reis JP, Isakova T, Wolf M, Carnethon MR. Racial differences in the associations between food insecurity and fibroblast growth factor 23 in the Coronary Artery Risk Development in Young Adults (CARDIA) Study. J Ren Nutr.2020 Mar 5;.doi: 10.1053/j.jrn.2020.01.020.[Epub ahead of print]PubMed PMID: 32147284. 122. Mwasongwe SE, Tanner RM, Poudel B, Pugliese DN, Young B, Abdalla M, Musani SK, Gutirrez OM, Correa A, Shimbo D, Muntner P. Ambulatory blood pressure phenotypes in adults taking antihypertensive medication with and without CKD. Clin J Am Soc Nephrol. 2020 Apr 7;15(4):501-510.doi: 10.2215/CJN.08840719.Epub 2020 Mar 26.PubMed PMID: 32217635; PMC7133126 123. Parcha V, Patel N, Kalra R, Kim J, Gutierrez OM, Arora G, Arora P. Incidence and Implications of Atrial Fibrillation/Flutter in Hypertension: Insights From the SPRINT Trial.Hypertension.2020 Jun;75(6):1483-1490.doi: 10.1161/HYPERTENSIONAHA.120.14690.Epub 2020 May 4.PubMed PMID: 32362231; PubMed Central PMCID: PMC7225039 124. Gutierrez OM, Porter A, Viggeswarapu M, Roberts J, Beck GR Jr. Effects of phosphorus and calcium to phosphorus consumption ratio on mineral metabolism and cardiometabolic health. J Nutr Biochem.2020; 80:108374.doi: 10.1016/j.jnutbio.2020.108374.Epub 2020 Mar 19.PubMed PMID: 32278118; PubMed Central PMCID: PMC7242166. 125. Drew DA, Katz R, Kritchevsky S, Ix JH, Shlipak MG, Newman AB, Hoofnagle AN, Fried LF, Sarnak M, Gutierrez OM. Fibroblast Growth Factor 23 and Blood Pressure in Older Adults: The Health, Aging, and Body Composition Study. Hypertension.2020;76(1):236-243.doi: 10.1161/HYPERTENSIONAHA.120.14703.Epub 2020 May 18.PubMed PMID: 32418499; PubMed Central PMCID: PMC7289679 126. Tummalapalli SL, Vittinghoff E, Crews DC, Cushman M, Gutierrez OM, Judd SE, Kramer HJ, Peralta CA, Tuot DS, Shlipak MG, Estrella MM.Chronic Kidney Disease Awareness and Longitudinal Health Outcomes: Results from the REasons for Geographic And Racial Differences in Stroke Study.Am J Nephrol.2020 Apr 29; 1-10.doi: 10.1159/000507774.[Epub ahead of print]PubMed PMID: 32349001 127. Womack R, Berru F, Panwar B, Gutierrez OM. Effect of ferric citrate vs. ferrous sulfate on iron and phosphorus parameters in patients with iron deficiency and CKD. Clin J Am Soc Nephrol 2020 Jul 21; CJN.15291219. doi: 10.2215/CJN.15291219. [Epub ahead of print] PubMed PMID: 32694162 128. Paul S*, Judd SE, Wang HE, Gutierrez OM. Association of FGF23 with incident sepsis in community-dwelling adults: a cohort study. Kidney360 2020; [Epub ahead of print]. 129. Hsu S, Hoofnagle AN, Gupta DK, Gutierrez OM, Peralta CA, Shea S, Allen NB, Burke G, Michos ED, Ix JH, Siscovick D, Psaty BM, Watson KE, Kestenbaum B, de Boer IH, Robinson-Cohen C. Race, ancestry and vitamin D metabolism: The Multi-Ethnic Study of Atherosclerosis. J Clin Endocrinol Metab.2020 Sep 1;.doi: 10.1210/clinem/dgaa612.[Epub ahead of print]PubMed PMID: 32869845. 130. Schrauben SJ, Shou H, Zhang X, Anderson AH, Bonventre JV, Chen J, Coca S, Furth SL, Greenberg JH, Gutierrez OM, Ix JH, Lash JP, Parikh CR, Rebholz CM, Sabbisetti V, Sarnak MJ, Shlipak MG, Waikar SS, Kimmel PL, Vasan RS, Feldman HI, Schelling JR. Association of Multiple Plasma Biomarker Concentrations with Diabetic Kidney Disease Progression: Findings from the Chronic Renal Insufficiency Cohort (CRIC) Study. J Am Soc Nephrol. 2020; In press. 131. Matsushita K, Jassal SK, Sang Y, Ballew SH, Grams ME, Surapaneni A, Arnlov J, Bansal N, Bozic M, Brenner H, Brunskill NJ, Chang AR, Chinnadurai R, Cirillo V, Correa A, Ebert N, Eckardt KU, Gansevoort RT, Gutierrez OM, Hadaegh F, He J, Hwang SJ, Jafar TH, Kayama T, Kovesdy CP, Landman GW, Levey AS, Lloyd-Jones DM, Major R, Miura K, Muntner P, Nadkarni GN, Naimark DMJ, Nowak C, Ohkubo T, Pena MJ, Polkinghorne KR, Sabanayagam C, Sairenchi T, Schneider MP, Shalev V, Shlipak M, Solbu MD, Stempniewicz N, Tollitt J, Valdivielso JM, van der Leeuw J, Wang AYM, Wen CP, Woodward M, Yamagishi K, Yatsuya H, Zhang L, Schaeffner E, Coresh J. Incorporating kidney disease measures into cardiovascular risk prediction: Development and validation in 9 million adults from 72 datasets. eClinicalMedicine. 2020; In press. 132. Tripathy S, Cai X, Adhikari A, Kershaw K, Peralta C, Kramer H, Jacobs DR Jr, Gutierrez OM, Carnethon MR, Isakova T. Association of Educational Attainment with Incidence of Chronic Kidney Disease in Young Adults. Kidney Int Rep 2020, In Press Reviews, Editorials and Case-reports 1. Gutirrez OM, Lin HY. Refractory Hyponatremia. Kidney Int 2007; 71:79-82. [PMID 16985516] 2. Yao J, Gutirrez OM, Reiser J. Emphysematous Pyelonephritis. Kidney Int 2007; 71:462-5; 2007. [PMID 17136032] 3. Felgueiras J, Gutirrez O, Tullius S, Tinckam K. Reversible posterior leukoencephalopathy syndrome in a renal transplant patient. Port J Nephrol Hypert 2008; 22: 201-204. 4. Isakova T, Gutirrez OM, Wolf M. A blueprint for randomized trials targeting phosphorus metabolism in chronic kidney disease. Kidney Int 2009; 76:705-16. [PMID 19606082] 5. Gutirrez OM, Wolf M. Dietary Phosphorus Restriction in Advanced Chronic Kidney Disease: Merits, Challenges, and Emerging Strategies. Semin Dial. 2010; 23(4): 401-6. [PMID 20557490] 6. Gutirrez OM. Fibroblast Growth Factor 23 and Disordered Vitamin D Metabolism in Chronic Kidney Disease: Updating the Trade-off Hypothesis. Clin J Am Soc Nephrol. 2010; 5(9): 1710-6. [PMID 20507957] 7. Gutirrez OM. Increased Serum Phosphate and Adverse Clinical Outcomes: Unraveling Mechanisms of Disease. Curr Opin Nephrol Hypertens. 2011; 20 (3): 224-8. [PMID 21245961] 8. Gutirrez OM. Recent Insights into Racial Differences in Bone and Mineral Metabolism. Curr Opin Endocrinol Diabetes Obes. 2011; 18(6):347-51. [PMID: 21897219] 9. Gutirrez OM. Sodium and phosphorus-based food additives: persistent but surmountable hurdles in the management of nutrition in chronic kidney disease. Adv Chronic Kidney Dis 2013; 20(2):150-6 [PMID: 23439374] [PMC3582990] 10. Gutirrez OM. Fibroblast growth factor 23, Klotho and disordered mineral metabolism in chronic kidney disease: unraveling the tapestry of events and implications for therapy. J Renal Nutr 2013; 23(3):250-4. [PMC3635040] 11. Gutirrez OM, Ix JH. Klotho and kidney function decline: an important step forward to understanding the link between mineral metabolism with kidney disease progression (editorial). Am J Kidney Dis 2013; 61(6):855-7. [PMID 23684489] 12. Saxena N, Gutirrez OM. Fibroblast growth factor 23, vitamin D and health disparities among African Americans with chronic kidney disease. Sem Nephrol. 2013; 33:448-456. [PMC3796770] 13. Gutirrez OM. The connection between dietary phosphorus, cardiovascular disease and mortality: where we stand and what we need to know. Adv Nutr. 2013; 4(6):723-729. PMC3823521 14. Gutirrez OM, Rostand SG. Chronic kidney disease in African Americans: past, present and future. Semin Nephrol. 2013; 33(5):407-8. [PMID 24119845] 15. Gutirrez OM. Contextual poverty, nutrition and chronic kidney disease. Adv Chronic Kidney Dis 2015; 22 (1):31-38. PMC4291540 16. Gutirrez OM. Fibroblast growth factor 23 and heart failure: the plot thickens (editorial). Nephrol Dial Transplant 2015; 31(5):688-90. PMID 26614271 PMC4902866 17. Gutirrez OM. Connecting the dots on fibroblast growth factor 23 and left ventricular hypertrophy (editorial). Nephrol Dial Transplant 2016; 31(7):1031-3. PMID 26786549 18. Panwar B, Gutirrez OM. Disorders of iron metabolism and anemia in chronic kidney disease. Sem Nephrol. 2016; 36(4):252-261. PMID: 27475656 19. Isakova T, Nickolas TL, Denburg M, Yarlagadda S, Weiner DE, Gutirrez OM, Bansal V, Rosas SE, Nigwekar S, Yee J, Kramer H. KDOQI US commentary on the 2017 KDIGO clinical practice guideline update for the diagnosis, evaluation, prevention, and treatment of chronic kidney disease-mineral and bone disorder (CKD-MBD). Am J Kidney Dis. 2017; [Epub ahead of print] PMID: 28941764 20. Melamed ML, Chonchol M, Gutirrez OM, Kalantar-Zadeh K, Kendrick J, Norris K, Scialla JJ, Thadhani R. The role of Vitamin D in CKD Stages 3 to 4: report of a scientific workshop sponsored by the National Kidney Foundation. Am J Kidney Dis. 2018; [Epub ahead of print] PMID 30297082 21. Gutirrez OM. Risks of anticoagulation in patients with chronic kidney disease and atrial fibrillation: more than just bleeding? Res Pract Thomb Haemost. 2019; 3(2): 147-148. PMID 31011695, PMC6462735 22. Day AL, Gutirrez OM, Saag KG. Burosumab in Tumor-Induced Osteomalacia: A Case Report. Joint Bone Spine. 2019 Aug 2;.doi: 10.1016/j.jbspin.2019.07.012.[Epub ahead of print]PubMed PMID: 31382017. 23. Gutirrez OM. Fibroblast growth factor 23 and the last mile. Clin J Am Soc Nephrol.2020 Sep 7;15(9):1355-1357.doi: 10.2215/CJN.13631119.Epub 2020 Apr 10.PubMed PMID: 32276945 24. Scialla JJ, Kendrick J, Uribarri J, Kovesdy CP, Gutirrez OM, Yakes Jimenez E, Kramer HJ. State-of-the-Art Management of Hyperphosphatemia in Patients with CKD: An NKF-KDOQI Controversies Perspective. Am J Kidney Dis.2020 Aug 6;.doi: 10.1053/j.ajkd.2020.05.025.[Epub ahead of print]PubMed PMID: 32771650. Non-peer reviewed 1. Gutirrez OM. Parathyroid Hormone, Alkaline Phosphatase, and Fibroblast Growth Factor 23: Which of these markers of mineral metabolism are the most appropriate to measure in patients with chronic kidney disease? Renal Urology and News. 2011. Book Chapters: 1. Gutirrez OM. Disorders of phosphorus homeostasis: emerging risk factors for kidney disease progression. Nutritional Management of Renal Disease, Third Edition. Eds. Kopple J, Massry S, Kalantar-Zadeh K. Academic Press. 2012 2. Gutirrez OM. Fibroblast Growth Factor 23, Klotho and Phosphorus Metabolism in Chronic Kidney Disease. Oxford Textbook of Clinical Nephrology, Fourth Edition. Eds. Goldsmith D, Winearls C, Wanner C, Lameire N, Himmelfarb J, Turner N and Remuzzi G. Oxford University Press. 2016 3. Gutirrez OM. The Story of Phosphorus. Clinical Aspects of Natural and Added Phosphorus in Foods. Nutrition and Health. Springer Science + Business Media: New York, 2017 4. Gutirrez OM. Vitamin D and Racial Differences in Chronic Kidney Disease. Vitamin D in Chronic Kidney Disease. Eds. Urena Torres PA, Cozzolino M, Vervloet MG. Springer International Publishing 2016 5. Gutirrez OM. Impact of socioeconomic factors on phosphorus balance. Dietary Phosphorus. Eds. Uribarri J Calvo M. CRC Press, 2018 6. Gutirrez OM. Phosphorus. Present Knowledge in Nutrition: Basic Nutrition and Metabolism, Eleventh Edition, Volume 1. Eds. Marriott B, Birt F, Stalling V, Yates A. Academic Press. 2020 Editor (Journals, Books): 1. Chronic kidney disease in African Americans: past, present, and future. Sem Nephrol 2013; Gutirrez OM and Rostand SG, guest editors. 2. Gutirrez OM, Kalantar-Zadeh K, Mehrotra R. (eds). Clinical Aspects of Natural and Added Phosphorus in Foods. Nutrition and Health. Springer Science + Business Media: New York, 2017. Media Poster Exhibits: 1. Gutirrez O, Isakova T, Rhee E, Holmes J, Collerone G, Jueppner H, and M Wolf. Fibroblast Growth Factor 23 Mitigates Hyperphosphatemia but Accentuates Calcitriol Deficiency in Chronic Kidney Disease. Poster presentation, National Kidney Foundation Spring Clinical Meetings, 2005. 2. Levin A, Gutirrez O, Andress D, Wolf M. Deficiencies of 25D, 1,25D, and Inflammation are Associated with Albuminuria. Poster presentation, American Society of Nephrology, Renal Week, 2007. 3. Gutirrez OM, Isakova T, Andress D, Levin A, Wolf, M. Prevalence and Severity of Disordered Mineral Metabolism in Blacks with Chronic Kidney Disease. Poster presentation, American Society of Nephrology Renal Week, 2007 4. Wolf M, Gutirrez O, Thadhani R. Interaction between Race, Active Vitamin D and Survival on Hemodialysis. Poster presentation, American Society of Nephrology, Renal Week 2007. 5. Gutirrez OM, Januzzi JL, Isakova T, Laliberte K, Smith K, Collerone G, Sarwar A, Hoffmann U, Coglianese E, Christenson R, Wang TJ, DeFilippi C, Wolf M. Fibroblast Growth Factor 23 and Left Ventricular Hypertrophy in Chronic Kidney Disease. Poster presentation, American Society of Nephrology Renal Week, 2008 6. Gutirrez OM, Anderson A, Isakova T, Scialla J, Negrea L, Anderson AH, Bellovich K, Chen J, Robinson N, Ojo A, Lash J, Feldman HI, Wolf M. Impact of Race and Socioeconomic Status on Serum Phosphate in the Chronic Renal Insufficiency Cohort (CRIC) Study. Poster presentation, American Society of Nephrology Renal Week, 2009 7. Isakova T, Gutirrez O, Anderson C, Rosen L, Theurer J, Bellovich K, He J, Steigerwalt S, Anderson AH, Tang I, Townsend R, Feldman H, Wolf M. Impact of Diuretic Choice on Secondary Hyperparathyroidism in Early CKD. Poster presentation, American Society of Nephrology Renal Week, 2009. 8. Gupta C, Anderson B, Gutirrez OM. Seasonal Variation in 25-hydroxyvitamin D Levels is Attenuated in Chronic Kidney Disease. Poster presentation, American Society of Nephrology Renal Week, San Diego, CA, 2009 9. Carvalho C, Isakova T, Olbina G, Wolf M, Westerman M, Gutirrez OM. Hepcidin and disordered mineral metabolism in chronic kidney disease. Poster presentation, American Society of Nephrology Renal Week, Denver, CO 2010. 10. Houston J, Isakova T, Smith K, Sowden N, Wahl P, Wolf M, Gutirrez OM. Relationships between FGF23, Dietary Phosphorus, Urinary Phosphate and Vascular Stiffness. National Kidney Foundation Spring Clinical Meetings, Las Vegas, NV 2011. 11. Gutirrez OM, Judd SE, Muntner P, Rizk DV, McClellan W, Safford M, Cushman M, Howard VJ, Howard G, Warnock DG. Albuminuria, Kidney Function and Risk of Incident Stroke in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study. Poster presentation, American Society of Nephrology Kidney Week, Philadelphia, PA 2011. 12. Joergensen C, Reinhard H, Gutirrez O, Wolf MS, Parving HH, Jacobsen PK, Rossing P. FGF23 and Asymptomatic Coronary Artery Disease in Type 2 Diabetic Patients with Elevated Urinary Albumin Excretion Rate. Poster presentation, American Society of Nephrology Kidney Week, Philadelphia, PA 2011. 13. Schmidt RJ, Pellegrino BS, Judd SE, Muntner P, Warnock DG, Bradbury BD, Gutirrez O, McClellan WM. Hypoalbuminemia, Mortality and Chronic Kidney Disease (CKD) among Participants of the REGARDS Study. Poster presentation, American Society of Nephrology Kidney Week, Philadelphia, PA 2011. 14. Gutirrez OM, Muntner P, Rizk DV, McClellan WB, Warnock DG, Judd SE. Dietary patterns and mortality in chronic kidney disease. Poster presentation, American Society of Nephrology Kidney Week, San Diego, CA, 2012. 15. Smith KT, deFilippi C, Isakova T, Gutirrez OM, Laliberte KA, Seliger SL, Kelley W, Duh SH, Hise MK, Christenson R, Wolf MS, Januzzi J. Fibroblast growth factor 23, high-sensitivity cardiac troponin, and left ventricular hypertrophy in chronic kidney disease. Poster presentation, American Society of Nephrology Kidney Week, San Diego, CA, 2012 16. Gutirrez OM, Khodneva Y, Muntner P, Rizk DV, McClellan WM, Cushman M, Warnock DG, Safford MM. Racial differences in albuminuria and risk of coronary heart disease. Poster presentation, American Heart Association Epidemiology and Prevention/Nutrition, Physical Activity and Metabolism 2013 Scientific Sessions, New Orleans, LA, 2013 17. Panwar B, Jenny NS, Bradley VG, Kissela B, Muntner P, Howard VJ, Judd SE, Gutirrez OM. Fibroblast growth factor 23 and risk on incident stroke in the REGARDS Study. International Stroke Conference, San Diego, CA, 2014 18. Judd SE, Muntner P, Kissela B, Jenny N, Warnock DG, Panwar B, Wadley VG, Howard VJ, Gutirrez OM. Vitamin D deficiency is associated with stroke in black and white participants of the REGARDS study. International Stroke Conference, San Diego, CA, 2014 19. Panwar B, Jenny NS, Howard VJ, Wadley WG, Muntner P, Kissela BM, Judd SE, Gutirrez OM. Fibroblast growth factor 23 and risk of incident stroke in community-dwelling adults. Poster presentation, American Society of Nephrology Kidney Week, Philadelphia, PA 2014 Oral Presentations: 1. Gutirrez OM, Tamez H, Bhan I, Zazra J, Tonelli M, Wolf M, Januzzi JL, Chang Y, Thadhani R. Early Mortality after Initiating Chronic Hemodialysis (HD): A U.S. Prospective Study of 10,000 patients. Oral abstract presentation, American Society of Nephrology Renal Week, 2007 2. Isakova T, Gutirrez O, Chang Y, Shah A, Tamez H, Smith K, Thadhani R, Wolf M. Phosphorus Binders and Survival on Hemodialysis. Oral abstract presentation, American Society of Nephrology Renal Week, 2008. 3. Gutirrez OM, Andress DL, Coyne DW, Levin A, Wolf M. Vitamin D Deficiency and Anemia in Early Chronic Kidney Disease. Oral abstract, American Society of Nephrology Renal Week, 2008 4. Thadhani R, Sampath K, Karumanchi SA, Tamez H, Bhan I, Isakova T, Gutirrez O, Wolf M, Chang Y, Stossel TP, Lee PS. Plasma Gelsolin Deficiency, Circulating Actin, and Hemodialysis Mortality. Oral abstract, American Society of Nephrology Renal Week, 2008 5. Gutirrez OM, Isakova T, Wolf M. (1-34) Parathyroid hormone infusion acutely lowers fibroblast growth factor 23 concentrations in healthy volunteers. Oral abstract, American Society of Nephrology Renal Week, Denver, CO 2010. 6. Tuot DS, Judd SE, Muntner P, Plantinga LC, Hsu CY, Warnock DG, Gutirrez O, Safford MM, Power NR, McClellan WM. Chronic Kidney Disease Awareness and Healthy Behaviors in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Cohort. Oral abstract, American Society of Nephrology Kidney Week, 2011. 7. 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