ࡱ> SWR =bjbj 40xx ; !!!!!5558m$L58>(."6 8888888;=8!BBB8!!8BBBB!!8BB8BB1B4?5B2p88082{@B{@4B4B4n{@!4BBBBBBBB88BBBB8BBBB{@BBBBBBBBB : Possible Side Effects of Bleomycin, Doxorubicin, Cyclophosphamide, Vincristine, and Prednisone (Table Version Date: October 8, 2013) COMMON, SOME MAY BE SERIOUS In 100 people receiving Bleomycin, Doxorubicin, Cyclophosphamide, Vincristine, and Prednisone (BACOP), more than 20 and up to 100 may have:Peeling of skin Changes in skin color Hair loss Fever Sores in mouth which may cause difficulty swallowing Scarring of the lungs which may cause shortness of breath Constipation, nausea, vomiting, loss of appetite Infection, especially when white blood cell count is low Absence of menstrual period which may decrease the ability to have children Blood in urine In children and adolescents: decreased height Loss of bone tissue Mood swings Skin changes, acne Swelling of the body, tiredness, bruising High blood pressure which may cause headaches, dizziness, blurred vision Pain in belly Increased appetite and weight gain Weight gain in the belly, face, back and shoulders Pain or redness at the site of injection Numbness and tingling of fingers or toes Headache, jaw pain and/or muscle pain Weakness and difficulty walking Red colored urine, saliva, or sweat OCCASIONAL, SOME MAY BE SERIOUS In 100 people receiving Bleomycin, Doxorubicin, Cyclophosphamide, Vincristine, and Prednisone (BACOP), from 4 to 20 may have:Blood clot which may cause swelling, pain, shortness of breath Stroke which may cause paralysis, weakness, headache Sores on the skin Sores in the mouth, throat or stomach Liver damage which may cause yellowing of eyes and skin, swelling Confusion Swelling of the brain Blood in urine Kidney damage which may require dialysis Damage to the bone marrow (irreversible) which may cause infection, bleeding, may require transfusions Loss or absence of sperm which may lead to an inability to father children Stuffy nose Fluid around the heart Cloudiness of the eye, visual disturbances Glaucoma Non-healing wound Diabetes Damage to the bone which may cause joint pain and loss of motion Kidney stones Heartburn Anemia which may cause tiredness, or may require transfusion Drooping eyelids Hoarseness Heart failure or heart attack which may cause shortness of breath, swelling of ankles, cough or tiredness which may occur years after the dose Swelling of the body which may cause shortness of breath Swelling and redness at the site of the medication injection or area of previous radiation Diarrhea Hepatitis which may cause yellow eyes and skin Allergic reaction which may cause rash, low blood pressure, wheezing, shortness of breath, swelling of the face or throat Cancer of the bone marrow (leukemia) caused by chemotherapy Damage to organs which may cause infection, bleeding, may require transfusions Darkening of the nail beds or skin or hands and feet Loss of nails RARE, AND SERIOUS In 100 people receiving Bleomycin, Doxorubicin, Cyclophosphamide, Vincristine, and Prednisone (BACOP), 3 or fewer may have:Severe skin rash with blisters and peeling which can involve mouth and other parts of the body Damage to the heart or heart failure which may cause shortness of breath, swelling of ankles, cough or tiredness A new cancer including cancer of bone marrow (leukemia) caused by chemotherapy Bleeding from sores in the stomach Broken bones Seizure Bruising, bleeding Severe blood infection     Page  PAGE 1 of  NUMPAGES 2 1CN^_t}    + , - . 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