Corpus ID: 7721728

Exercise and neuroplasticity in persons living with Parkinson's disease.

@article{Hirsch2009ExerciseAN,
  title={Exercise and neuroplasticity in persons living with Parkinson's disease.},
  author={Mark Alexander Hirsch and Becky G. Farley},
  journal={European journal of physical and rehabilitation medicine},
  year={2009},
  volume={45 2},
  pages={
          215-29
        }
}
  • M. Hirsch, B. Farley
  • Published 2009
  • Medicine
  • European journal of physical and rehabilitation medicine
For many years, exercise was not a recommended rehabilitation strategy for persons with a diagnosis of idiopathic Parkinson's disease (PD). Since it was believed that exercise had no measurable effect on PD, or might worsen the underlying pathology, it was to be avoided. A rich vein of bench and translational research now suggest non-pharmacological approaches, such as exercise or physiotherapy, have a far greater effect on the cardinal features of PD than previously believed. In particular… Expand
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References

SHOWING 1-10 OF 113 REFERENCES
Rehabilitation and neurologic repair in Parkinson's disease.
TLDR
This special issue explores current and future approaches to neurorehabilitation in PD and identifies risk factors for falling in PD appropriately grounded within the context of falling in the elderly. Expand
Parkinson's disease and resistive exercise: Rationale, review, and recommendations
TLDR
A clear rationale for the efficacy of resistance training in individuals with Parkinson's disease is established and musculoskeletal weakness and its relationship to function as well as potential training‐induced adaptive alterations in the neuromuscular system are highlighted. Expand
Restorative effect of endurance exercise on behavioral deficits in the chronic mouse model of Parkinson's disease with severe neurodegeneration
TLDR
This study indicates that in spite of the drastic loss of dopaminergic neurons and depletion of dopamine in the severe chronic MPD, endurance exercise training effectively reverses the Parkinson's like behavioral deficits related to regular movement, balance and gait performance. Expand
Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease
TLDR
It is demonstrated that exercise following nigrostriatal damage ameliorates related motor symptoms and neurochemical deficits in rodent models of PD. Expand
Endurance exercise promotes cardiorespiratory rehabilitation without neurorestoration in the chronic mouse model of Parkinsonism with severe neurodegeneration
TLDR
It is suggested that 4 weeks of treadmill exercise promoted physical endurance, resulting in cardiorespiratory and metabolic adaptations in the chronic parkinsonian mice with severe neurodegeneration without demonstrating a restorative potential for the nigrostriatal dopaminergic function. Expand
Forced Nonuse in Unilateral Parkinsonian Rats Exacerbates Injury
TLDR
Results suggest decreased physical activity not only is a symptom of PD but also may act to potentiate the underlying degeneration. Expand
Neurobiology of exercise
TLDR
Mechanisms explaining these adaptations are not as yet known, but metabolic and neurochemical pathways among skeletal muscle, the spinal cord, and the brain offer plausible, testable mechanisms that might help explain effects of physical activity and exercise on the central nervous system. Expand
The effect of exercise training in improving motor performance and corticomotor excitability in people with early Parkinson's disease.
TLDR
The findings suggest the dose-dependent benefits of exercise and that high-intensity exercise can normalize corticomotor excitability in early PD. Expand
Stress reduces the neuroprotective effect of exercise in a rat model for Parkinson's disease
TLDR
The behavioural results confirm a previous finding suggesting that voluntary exercise is neuroprotective and a novel finding is that mild stressors cancel the neuroprotection afforded by voluntary exercise. Expand
Clinical relevance of rehabilitation programs for Parkinson's disease. I: Non-symptom-specific therapeutic approaches.
TLDR
A rating system was developed considering effectiveness, everyday life relevance, long-term effect, therapy frequency and setting, duration of the therapy units, effects on quality of life, and assessment and found four studies with a Level I of statistical quality and four Studies with high clinically relevant information. Expand
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