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A6ϢVV4*`y]zqx   Operational Obstetrics & Gynecology The Health Care of Women in Military Settings 2nd Edition  NAVMEDPUB 6200-2A  Table of Contents Introduction 1 Military Medicine 1 Womens Health Care 1 Women in the Military 2 Purpose of this Manual 2 Routine Gynecologic Care 4 Annual Exam 4 Chief Complaint 4 Medical History 4 Medications 4 Menstrual History 5 Pregnancy History 5 Contraception 5 Nutrition 5 Exercise 5 Mood 6 Physical Exam 6 Weight 6 Blood Pressure 7 Face and Eyes 7 Ears 7 Thryoid 7 Lungs 7 Heart 7 Breasts 7 Abdomen 7 Pelvic Exam 7 Pap Smear 8 Cultures 8 Rectal 8 Urine 9 Wet Mount 9 Mammography 9 Breast Self-Exam 9 Immunizations 10 Counseling 10 Plan 10 Pap Smears The Cervix 11 The Pap Smear 11 Position the Patient 12 Field Expedient Exam Table 12 Pad the Stirrups 13 Inspect the Vulva 13 Warm the Speculum 13 Insert the Speculum 13 Field Expedient Speculum 14 Start with the Spatula 14 Rotate the Spatula 14 Sample the Squamocolumnar Junctions 15 Make a Thin Smear 15 Spray Immediately 15 Next Use a Brush 15 Insert and Rotate 180 Degrees 15 Dysplasia 16 Mild Dysplasia 16 Moderate Dysplasia 17 Severe Dysplasia 18 Carcinoma in Situ 18 Invasive Cancer of the Cervix 19 Adenocarcinoma of the Cervix 19 Visible Lesions on the Cervix 19 Colposcopy 19 Actinomycosis 20 AGUS 20 Atrophy 20 ASCUS 20 Candida 21 Chlamydia 21 CIN 22 Coccoid Bacteria 22 Condyloma 22 Drying Artifact 22 Endocervical Cells Not Present 23 Endometrial Cells Present 23 Estrogen Effect 23 Gardnerella 24 Herpes 24 HPV 24 Inadequate Smear 24 Inconclusive Smear 25 Inflammation 25 IUD Changes 25 Koilocytosis 25 Leptothrix 25 Nuclear Atypia 26 Reparative or Reactive Changes 26 SIL 26 Squamous Metaplasia 26 Trichomonas 27 Birth Control Pills 28 Benefits of BCPs 28 Risks of BCPs 28 Which Pill to Start 29 Starting the Pill 29 When are the Pills Effective? 29 Skipped a Pill 30 History of Migraine Headaches 30 High Blood Pressure 30 Diabetes 30 Blood Clot History 31 Non Availability of her Pill 31 Postponing a Period with BCPs 31 Side Effects 32 Breast Tenderness 32 Nausea 33 Weight Gain 33 Headaches 33 Moodiness or Depression 34 Vaginal Dryness 34 Decreased Libido (Sex-Drive) 34 Painful Menstrual Cramps 34 Continuous Birth Control Pills 35 No Period or very Light Period 36 Spotting Between Periods 37 Periods at the Wrong Time 37 Antibiotics 38 Thinks she may be Pregnant 38 Emergency Contraception 38 Overdose 39 Other Contraceptive Methods 41 Condoms 41 Diaphragm 42 DMPA (Depot Medroxyprogesterone Acetate) 43 Female Condom 45 Contraceptive Vaginal Film 46 Contraceptive Foam 47 Contraceptive Vaginal Gel 47 Intrauterine Device (IUD) 48 Norplant 51 Rhythm 53 Vaginal Suppositories 54 Tubal Ligation 54 Vasectomy 55 Withdrawal 55 Bleeding 57 Normal Bleeding 57 Abnormal Bleeding 57 Overview 57 Pregnancy Problems 58 Mechanical Problems 58 Hormonal Problems 58 Malignancy 59 What to do First 59 Heavy Periods 59 Light Periods 60 Late for a Period 61 Irregular Periods 61 Too Frequent Periods 61 Constant Bleeding 62 Hemorrhage 63 Vaginal Discharge and Itching 65 Overview 65 History 65 Physical Exam 65 Laboratory 66 Treatment 66 Ectropion, Erosion or Eversion 66 Cervicitis 67 Chlamydia 67 Foreign Body 67 Bacterial Vaginosis 68 Gonorrhea 68 Infected IUD 69 PID: Mild 69 PID: Moderate to Severe 69 Trichomonas 70 Yeast (Monilia, Thrush) 71 Human Papilloma Virus 72 Clinical Warts 72 Subclinical Warts 72 Treatment 72 Persistence of Virus 73 Transmission 73 Dysplasia 73 Relation to Cancer 74 Evualuation 74 The Vulva 75 General 75 Bartholin Cyst and Abscess 75 Chancroid 76 Condyloma Lata 76 Contact Dermatitis 77 Epithelial Polyp 77 Granuloma Inguinale 78 Herpes Vulvitis 78 Hypertrophic Vulvar Dystrophy 79 Inclusion Cyst 80 Itching 80 Labial Abscess 81 Lichen Sclerosis 81 LGV 82 Melanosis 83 Molluscum Contagiosum 83 Pagets Disease 83 Pediculosis Pubis (Pubic Lice) 84 Primary Syphilis 84 Runners Rash 85 Scabies 85 Skenes Gland 86 Tinea Cruris (Jock Itch) 87 VIN 88 Vulvar Cancer 88 Vulvar Hematoma 88 Vulvar Dystrophy 89 Vulvar Vestibulities 90 Yeast (Candida, Monilia) 90 Problems with Menstruation 93 Normal Menstrual Flows 93 Cramps 93 Breast Pain 94 Midcycle Pain 95 Acne 95 Headache 95 Fluid Retention 96 Abdominal Bloating 96 Depression and Irritability 97 Abdominal and Pelvic Pain 98 Uncertainty of Diagnosis 98 Pain and Bedrest 98 Pain and Fever 98 Chronic Pain 99 Pregnancy Test 99 BCPs and Pain 99 Pregnancy and Bleeding 99 Threatened Abortion 100 Ectopic Pregnancy 100 Placental Abruption 100 Placenta Previa 101 IUD Problems 102 Ovarian Cyst 102 Ruptured Ovarian Cyst 102 Unruptured Ovarian Cyst 103 Torsioned Ovarian Cyst 103 Dysmenorrhea 103 Mittelschmerz 104 Functional Bowel Syndrome 104 Gastroenteritis 104 Diverticular Disease 104 PID 105 PID: Mild 105 PID: Moderate to Severe 105 Endometriosis 106 Appendicitis 107 Bowel Obstruction 107 Degenerating Fibroid 108 Infected or Rejected IUD 108 Cystitis 108 Pyelonephritis 109 Problems with Urination 110 Painful Urination 110 Gonorrheal Urethritis 110 Non-gonorrheal Urethritis 111 Herpes 112 Yeast, Trichomonas 112 Urinary Frequency 112 Blood in the Urine 112 Bad Urinary Odor 113 Cannot Urinate 113 Bladder Training 113 Involuntary Loss of Urine 114 Stress Incontinence 114 Irritable Bladder 114 Urethral Diverticulum 114 Unpredictable Urine Loss 115 Urinary Urgency 115 Stress 115 Pyelonephritis 115 Breast Problems 116 Breast Development 116 Breast Examination 116 Breast Self-Exam 118 Mammography 119 Ultrasound 119 Breast Biopsy 120 Supernumerary Breasts 120 Supernumerary Nipples 120 Inverted Nipples 120 Adolescent Breast Problems 120 Pregnancy Changes 121 Puerperal Mastitis 121 Nipple Laceration 121 Cyclic Breast Pain 122 Non-cyclic Breast Pain 122 Nipple Discharge 122 Fat Necrosis 123 Pagets Disease 123 Breast Mass 123 Breast Cyst 124 Fibroadenoma 124 Breast Cancer 124 Menopause 126 Definition 126 Symptoms 126 Associated Medical Problems 126 Clinical Presentation 127 Philosophy of Management 127 Benefits of Treatment 127 Risks of Treatment 128 Alternatives 128 Standard Treatment 129 Birth Control Pills 130 Risk of Pregnancy 130 Libido (Sex Drive) 130 Follow-up 131 Sexual Assault 132 Outline of Management 132 Assign Staff Member 132 Serious Injuries Come First 132 Notify Authorities 133 Notify the Chaplain 133 Consent 133 Gather your Supplies 133 Labels 133 Materials Needed 134 History 134 Gynecologic History 135 Clothing 135 Physical Exam 135 Photographs 135 Head Combings 135 Mouth 135 Torso and Arms 136 Hands 136 Pubic Hair Combings 136 Inspect the Vulva 136 Visualize the cervix 137 Vaginal Swab 137 Chlamydia Culture 137 Gonorrheal Culture 137 Rectal Examination 137 Bimanual Exam 138 Betadine Douche 138 Let the Patient Shower 138 Blood and Urine Tests 138 Offer Antibiotics 138 Emergency Contraception 139 Follow-up Exam 139 Medical Release 140 Write your Report 140 Give Evidence to Investigator 140 Give Specimens to your Lab 140 Give Instructions to Patient 140 Special Case of Children 141 Normal Pregnancy 142 Diagnosis of Pregnancy 142 Pregnancy Tests 142 Prenatal Care 143 Check Weight 143 Check Blood Pressure 143 Measure Fundal Height 144 Listen for the Heartbeat 144 Check for Edema 144 Check Protein and Glucose 144 Ask about Fetal Activity 144 Any new Symptoms? 145 Nutrition 145 Prenatal Vitamins 145 Laboratory Tests 145 Ultrasound Scan 146 Estimating Gestational Age 146 Fetal Heart Beat 147 Disability 147 Maternal Skin Changes 147 Exercise in Pregnancy 148 Nausea and Vomiting 148 Heartburn 149 Sciatica 149 Carpal Tunnel Syndrome 149 Upper Respiratory Infections 150 Antibiotics During Pregnancy 150 Other Drugs During Pregnancy 151 Immunizations During Pregnancy 152 Thermal Stress 152 Noise 152 Vibration 153 Chemical Solvents 153 Heavy Metals 153 X-rays During Pregnancy 153 Radiation Exposure 153 CRT Use and Pregnancy 154 Diving While Pregnant 154 Hyperbaric Treatment 154 Pregnant Aircrew Members 155 Abnormal Pregnancy 156 Miscarriage 156 Abortion 156 Threatened Abortion 157 Complete Abortion 157 Incomplete Abortion 158 Inevitable Abortion 159 Septic Abortion 160 Unruptured Ectopic Pregnancy 161 Ruptured Ectopic Pregnancy 161 Blood Transfusion 162 First Trimester Trauma 163 Later Trauma 164 Placental Abruption 165 Placenta Previa 165 Toxemia of Pregnancy 166 Pre-eclampsia 167 Eclampsia 169 HELLP Syndrome 169 Normal Labor and Delivery 170 Labor 170 Latent Phase Labor 170 Active Phase Labor 171 Progress of Labor 171 Delivery of the Baby 172 Delivery of the Placenta 173 Managing Labor and Delivery 173 Initial Evaluation 173 History 174 Risk Factors 174 Vital Signs 175 Contractions 175 Fetal Heart Rate 175 Urine for Protein and Glucose 175 Estimated Fetal Weight 176 Dilatation and Effacement 176 Fetal Orientation 176 Leopolds Maneuvers 177 Status of Fetal Membranes 177 Blood Count 177 Management of Early Labor 178 Monitor the Fetal Heart 178 Electronic Fetal Monitors 179 Pain Relief 180 Second Stage Labor 182 Preparing for Delivery 182 Delivery 183 Episiotomy 183 Anesthesia 184 Clamp and Cut the Cord 184 The Placenta 184 Uterine Massage 185 Post Partum Care 185 Problems During Labor and Delivery 188 Preterm Labor 188 Premature Rupture of Membranes 189 Abnormal Presentation 190 Prolonged Latent Phase Labor 191 Arrest of Active Labor 191 Shoulder Dystocia 193 Breech Delivery 195 Twin Delivery 196 Prolapsed Umbilical Cord 196 Cord Around the Neck 197 Retained Placenta 197 Post Partum Hemorrhage 198 Chorioamnionitis 198 Group B Streptococcus 199 Post Partum Fever 200 Care of the Newborn 201 Dry the Baby 201 Replace the Wet Towels 201 Position the Baby 201 Suction the Airway 202 Evaluate the Baby 202 Color 202 Ventilate if Necessary 203 Check the Heartbeat 203 Keep the Baby Warm 203 Assign Apgar Score 204 Breast-feeding 204 Field-Expedient Bottle 204 Vernix 205 Meconium 205 Eye Prophylaxis 205 Vitamin K 205 Umbilical Cord Care 205 Medical Support of Women in Field Environments 207 Pre-deployment Planning 207 AMAL and Sick Call Block 207 Command Pregnancy Policy 209 Pre-Deployment Screening 210 Pre-Deployment Briefing 210 Urination Issues 211 Menstruation Issues 212 Bathing 213 Quarters 213 Clothing 214 Liberty Risks 215 Leadership 215 Host Nation Issues 216 Pregnancy 216 Noise 217 Heat 217 Organic Solvents 217 Lead, Cadmium, Mercury 217 Low Frequency, Whole Body Vibration 217 Prolonged Standing 217 STDs and Safe Sex 217 Aerospace Medicine Issues 218 Gravitational Forces 218 Decompression Sickness 218 Antorhropometrics 219 Pregnancy in Aviation 219 The Prisoner of War Experience The Prisoner of War 221 Sexual Abuse 221 The Total Soldier 222 Pre-Deployment Planning 222 The Typical Repatriated Soldier 222 Stresses of Captivity 222 Recovery 223 Appendix A: OPNAVINST 6000.1A - MANAGEMENT OF PREGNANT SERVICEWOMEN Appendix B: Ultrasound Measurements in Pregnancy Appendix C: Gestational Age Calculator Appendix D: SF600 Gynecologic Consultation Overprint Appendix E: Menstrual Flow Record Cards Appendix F: Phone Numbers for OB-GYN Consultation Acknowledgments A single person cannot produce a project of this magnitude. In preparing both the 1st and 2nd editions of Operational Obstetrics & Gynecology, I received invaluable assistance from many individuals. Among them are: From the Army Lieutenant General Ronald R. Blanck, MC, USA Major General James Peake, MC, USA Brigadier General Kevin C.Kiley, MC, USA Brigadier General Bettye H. Simmons, AN, USA Colonel Daniel F. Battafarano, MC, USA Colonel Carla Hawley-Bowland, MC, USA Colonel Rhonda Cornum, MC, USA Colonel Gary Davis, MC, USA Colonel Margaret J. Knapp, MC, USA Colonel John M. Powers, MC, USA Colonel Iris West, MC, USA Colonel Steve Yevich, MC, USA Colonel Craig H. Llewellyn, MC, USA (Ret) MSG James T. Bates, USA SFC Robert P. Roemer, USA SFC Bruce Ward, USA From the Navy Vice Admiral Richard K. Nelson, MC, USN Vice Admiral Harold M. Koenig, MC, USN (Ret) Vice Admiral Donald F. Hagan, MC, USN (Ret) Rear Admiral Joan M. Engel, NC, USN Rear Admiral Robert W. Higgins, MC, USN (Ret) Rear Admiral James Johnson, MC, USN Rear Admiral Richard A.Mayo, MC, USN Rear Admiral R.C. Melendez, DC, USN Rear Admiral William R. Rowley, MC, USN Rear Admiral James H. Black, MC, USN (Ret) Captain Michael R. Ambrose, MC, USN Captain Mary A. Anderson, MC, USN Captain Kathleen Bailey, NC, USN Captain Lee D. Bown, NC, USN Captain David Brice, MC, USN Captain Thomas R. Defibaugh, MSC, USN Captain John Fahey, MC, USN Captain Susan A. Flood, NC, USN Captain William Frank, MSC, USN Captain James Frazier, MC, USN Captain H. John Gerhard, MC, USN Captain B. Gail Goff, MSC, USN Captain Konrad E. Hayashi, MC, USN CaptainJanet L Higgins, NC, USN Captain Dave Hyland, MC, USN Captain Richard R. Jeffries, MC, USN Captain W. Robert Kiser, MC, USN Captain Joel Lees, MC, USN Captain Davonne Loup, MC, USN Captain Charles J. Macri, MC, USN Captain Donald Mason, MC, USN Captain Jay R. Montgomery, MC, USN Captain Charles B. Mount, MSC, USN Captain Patricia Murphy, NC, USN Captain John Murray, MC, USN Captain John Nickle, MC, USN Captain Robert B. North, Jr., MC, USN Captain Frank Nuar, MC, USNR Captain Donna Perry, NC, USN Captain Jerry Ragland, MC, USN Captain Terry Reiley, MC, USN Captain Steve Remmenga, MC, USN Captain Adam Robinson, MC, USN Captain David Sack, MC, USN Captain Dave Snyder, MC, USN Captain Robert Spiro, MC, USN Captain Don Sprague, MC, USN Captain Richard Stock, MC, USN Captain Glenn N. Wagner, MC, USN Captain Steve Warlick, MC, USN Captain Natalie Willenberg, MC, USN Captain Steve Yakavon, MC, USN Captain Jeffery M. Young, MC, USNR Captain H.B. Etienne, MC, USN (Ret) Captain John Nash, MC, USN (Ret) Captain John Noll, MC, USN (Ret) Captain Thakor G. Patel, MC, USN (Ret) Captain Henry Schwarz, MC, USN (Ret) Commander Steve Acher, MC, USN Commander Mark Austin, MC, USN Commander Linnea Axman, NC, USN Commander Tamara C. Babb, MC, USN Commander Michael Bandy, JAGC, USN Commander Barney R. Barendse, NC, USN Commander David Beardsly, MC, USN Commander Brad L. Bennett, MSC, USN Commander Monte L. Bible, MC, USN Commander Victoria A. Cassano, MC, USN Commander Soren Christensen, NC, USN Commander Bruce A. Cohen, MC, USN Commander James R. De Voll, MC, USN Commander Robert Frick, MC, USN Commander Dave Gillis, MC, USN Commander Terry A. Harrison, MC, USNR Commander Susan B. Herrold, NC, USN Commander Tim Hinman, MC, USN Commander Mary Owens, NC, USN Commander James Phelan, MC, USN Commander Paul Rocereto, MC, USN Commander Dennis Rowe, MC, USN Commander Scott W. Shiffer, NC, USN Commander Erica L.Spence, NC, USN Commander Tommy C. Stewart, NC, USN Commander Amy Suggs, NC, USN Commander Nancy Swanson, NC, USN Commander Jennifer Town, NC, USN Lieutenant Commander Josephine Brumit, NC, USN Lieutenant Commander Brian Belson, MC, USN Lieutenant Commander Ann Fallon, MC, USN Lieutenant Commander David A. Lane, MC, USN Lieutenant Commander John W. LeRoy, MSC, USN Lieutenant Commander Jennifer Polano, MC, USNR Lieutenant Commander Steve Presley, MC, USN Lieutenant Youssef H. Aboul-Enein, MSC, USN Lieutenant Paul Antony, MC, USN Lieutenant Chris Alewine, MC, USN Lieutenant Dennis Ashley, MC, USN Lieutenant Thomas A. Craig, MC, USN Lieutenant Angela Gardner, USN Lieutenant Jennifer M. Jagoe, MC, USN Lieutenant Frederick E. Yeo, MC, USN HMCM (AW) Reynaldo Angeles, USN HMCM (SW) J.E. Lambert, USN HMCM (SW) Mark R. Weldon, USN HMC (SW) Joe Fischer, USN HMC Charles Herbert, USN HMC Sally Hobson, USNR HMC (SW/FMF) Mike Judson, USN HM1 Michael J Brady, USN HM2 Christina Kenny, USN HM2 Aretha Paschel-Alexander, USN HM2 Nona Sanders, USN From the Marine Corps Major Anne Shuford, USMC Captain Lorrie Kovacs, USMC 1st Lieutenant Julie Ward, USMC 1st Lieutenant Jennifer M. Wolfe, USMC MGySgt Pat McLane, USMC MSgt Marian P. Frayser, USMC GySgt Shawnee J Miller, USMC SSgt Sara M. Gross, USMC Sgt Vicki R. Courson, USMC From the Air Force Lieutenant Colonel Susan E. Northrup, MC, USAF Lieutenant Colonel Michael W. Spatz, MC, USAF Lieutenant Colonel Chris Zahn, MC, USAF From the Coast Guard Captain Paul Higgins, USPHS Lieutenant Commander Sharon L. Ludwig,USPHS MCPO Glenn Proctor, USPHS From the United States Public Health Service Captain William H.J. Haffner, M.D., USPHS Others Ms. Ann Ballard, Bureau of Medicine and Surgery Mr. Henry "Hank" Champagne, Naval School of Health Sciences Ms. Patty Chilis, RDMS, Evanston Hospital, Evanston, IL Mr. Walt Dumbeck, Naval School of Health Sciences Ms. Laura Franz, Bureau of Medicine and Surgery Ms. Judy Goldman, Naval School of Health Sciences Ms. Margaret M. Grey, Federal Bureau of Investigation Mr. Jan K. Herman, Bureau of Medicine and Surgery Ms. Carol Kuzmanic, Evanston Hospital, Evanston, IL Ms. Jeri L. Lockman, MSN, ARNP, Office of Medical Services, U.S. Department of State Gretchen McCoy, MD, U.S. Department of State Ms. Evelmer Poole, Armed Forces Institute of Pathology Ms. Susan E. Rist, MCAS Miramar, CA Ms. Tracy Roberts, Medical Photography, Evanston Hospital, Evanston, IL Mr. Jerry Robinson, Center for Health Education and Studies, U.S. Army Medical Department Mr. Al Smith, Naval School of Health Sciences Ms. Kristine Vehlow, Evanston Hospital, Evanston, IL James E. Yoder, MD, MPH, FBIHQ Health Care Programs Unit, Federal Bureau of Investigation Introduction to the 2nd Edition When it was written in 1992, Operational Obstetrics & Gynecology was based primarily on my own personal experiences and perspectives, and focused on the needs of the sea-going population. In writing the 2nd Edition, I have tried to incorporate several changes: Ive expanded the applicability of the manual to the other areas of military operations (Air, Sea and Land). Ive added several chapters not covered in the 1st Edition. Ive solicited and incorporated changes and additions from operationally experienced medical providers from the Army, Navy, Marine Corps, Air Force and Coast Guard. Military Medicine Providing health care in military settings is similar, in some ways, to civilian settings and in some ways different. In civilian settings, the primary responsibility is to the patient, with secondary concerns from the insurance company, employer and family. In military settings, the primary responsibility is to the Command. In most cases, the interests of the Command and the interests of the patient are the same, particularly in a garrison setting. In a deployed setting, divergence of interest may occasionally arise, creating challenges for the military health care provider. Military medicine also differs from civilian medicine in three other fundamental ways: Medical providers are isolated. Medical resources are limited. Operational circumstances may influence the provision of medical care. It is because of these differences that clinical problems in an operational setting may be treated differently than the same clinical problem in a civilian setting. The principles of treatment are the same: the application of treatment may be different. Womens Health Care For the most part, women's health care needs are the same as men's health care needs. Women develop coughs, colds, stomach upsets, contusions, abrasions, and fractures. They need preventative care and immunizations. However, some of their health care needs are different: Women have some unique gynecologic and obstetric needs. Women may have different vulnerabilities to certain diseases or injuries. Women may use health care services differently than men. Women in the Military Military women are a unique group. They are a generally young, healthy population, pre-screened for most common, chronic diseases. They are, for the most part, physically fit and engage in regular exercise. Women in the military are, as a group, younger than their male counterparts, are of lower rank, sustain more stress fractures, and utilize health care services twice as often. Even after excluding female-specific reasons (OB, GYN), they still use health care services more often. In this regard, they are similar to civilian women who also use health care services more often. In most studies, like their civilian counterparts, although they use health care services more often, they are generally less satisfied with those services than men. Women in the military come from many backgrounds. Among Navy recruits, nearly half have been victims of physical domestic abuse prior to entry into the service, a figure similar to their male counterparts. As a group, women have: More self-reported chronic conditions and all acute conditions except injuries Higher illness rates More days of illness and disability 10% more acute conditions, particularly infections, respiratory problems and digestive conditions Poorer vision Poorer dental status Better hearing More genitourinary problems Less chronic illness leading to death Lower death rates About one-third of the OB-GYN health care visits made by military women are for routine care. Most of the remaining visits are for: STD diagnosis and treatment Menstrual abnormalities Vaginitis Urinary tract problems Pregnancy-related problems Purpose of this Manual This manual is designed to assist those who treat women with gynecologic problems and offer guidance for the continuing care of these women, particularly in isolated settings where gynecologic consultation is not readily available. The manual is not all-inclusive and is not intended to replace good clinical judgment nor in-depth textbooks, which should be consulted whenever appropriate. As in most areas of medicine, there may be more than one way to deal with any particular gynecologic problem. For simplicity, one basic approach is usually given here. There are often other approaches that will give very good or superior results. CAPT Michael John Hughey, MC, USNR Code 02SPO Special Projects Officer for the Assistant Chief, Operational Medicine and Fleet Support Bureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington, DC 20372-5300 Routine Gynecologic Care Annual Exam Once a year, a full gynecologic exam is indicated in women of childbearing years. This is an excellent opportunity for routine health screening and patient counseling. The amount of detail and the content of the exam will depend on many factors, but a typical, routine, examination is illustrated here. Many health care providers find it useful to utilize a standard form for recording information about this exam. An example is found in the back of this manual. Chief Complaint This is the reason for the visit. It might be for a routine GYN visit, or to refill birth control pills, or because of a troublesome vaginal discharge. The Chief Complaint can almost always be stated in one sentence or less. "What brings you to see me today? Medical History Ask how the patient has been since her last examination. This is an opportunity for you to get a current medical status report. You might ask: "Have you had any problems?" "How are you feeling today?" For patients not previously seen or for whom you have no medical records, you should note any previous significant medical or surgical illness, and allergies. "Have you every been hospitalized for any medical illness?" "Have you ever had any surgery? "Are you allergic to any medicine? Medications Ask her to identify medications she takes regularly. This will provide additional insight into her current health status and may identify areas of her medical history she has forgotten. "Are you taking any medication on a regular basis?" Menstrual History Record menstrual data. Age of onset of menses (menarche), the regularity (or irregularity) of menses, their frequency, duration, heaviness and any associated symptoms, such as cramps, bloating or headaches. Note the first day of the last menstrual period. LMP_________ Menarche age______ Menses are regular/irregular Menses Q_____ days x ______ days. Pregnancy History Determine the number and nature of pregnancies. Gravida (G) means the total number of pregnancies. Para (P) means the number of children born. Abortions (AB) means the number of spontaneous or induced abortions. G_______ P_______ AB_____ Contraception Inquire as to the method currently used for contraception. This may provoke an answer that opens the door to a discussion of sexual issues that may be troubling to her. Contraception__________________________________ Nutrition Assess the general nutritional status. This can be done visually and with noting her height and weight. For women with a normal, balanced diet, nutritional supplements are probably not necessary, but most people have difficulty maintaining a normal balanced diet. For those, a daily multivitamin can be very helpful in making up for any nutritional deficiencies. Additional iron is particularly helpful for women in maintaining a positive iron balance. Otherwise, the steady loss of iron through menstruation can lead to some degree of anemia. For women anticipating a pregnancy, Folic acid 400 mg PO daily is recommended by the Center for Disease Control to reduce the risk of birth defect related to the spine. I sometimes will ask: "Are you eating a normal, balanced diet ?" "Do you normally take a vitamin pill?" Exercise Regular exercise is important for physical and psychological reasons. Women who exercise regularly will generally experience less trouble with cardiovascular disease, bone loss (osteoporosis), weight control, and depression. To be most effective, the exercise should be strenuous enough to cause sweating, last at least 20 minutes, and occur several times a week. Lesser amounts of exercise may also be beneficial. "Do you get a chance to exercise regularly?" As a group, women are more likely to sustain minor athletic injuries, for reasons that may include level of training or fitness, degree of experience with exercise, architectural construction of the pelvis and lower limbs, and possibly hormonal effects. It is important to try to avoid athletic injuries while continuing to exercise. Try not to perform the same exercise two days in a row...give the body 48 hours to recover. If a certain exercise causes pain, either modify it or discontinue it so that the pain does not persist. Gradually increase the duration and intensity of training and avoid sudden large increases that may lead to overuse injuries. Mood Depression is a common clinical problem affecting twice as many women as men. Talking with the patient will give you a reasonable assessment of her mood. Depression is diagnosed whenever a depressed mood or loss of interest/pleasure is associated with at least four other symptoms, consistently over a two-week period. (DSM-IV) Depressed mood most of the day, most days Marked loss of interest in normal activities most of the day, most days >5% change in body weight in 1 month when not intentionally trying to modify body weight Insomnia or too much sleep most nights Psychomotor agitation or depression most of the time Marked fatigue nearly every day Feeling worthless or inappropriately guilty most of the time Diminished ability to think or make decisions most days Recurring thoughts of death or suicide Physical Exam While some physicians perform each of these evaluations at every routine gynecologic visit, some perform only those which focus on specific issues for the specific patient. Weight Weigh the patient. Make an assessment of how her weight fits with standards for good health. Too much and too little weight are both problems. Compare the weight with previous weights to assess the trend. Blood Pressure Measure the blood pressure and the other vital signs. Particularly among older women, elevated blood pressure is a common problem and one that may be effectively controlled or treated. Uncontrolled elevated blood pressure is associated with a number of serious medical consequences. Face and Eyes Look in her eyes. Watch they eyes for symmetry, proportion, focus, white sclerae, and movement. Look for any facial muscle weakness appearing as a droop or asymmetry. Eye movements should be coordinated. The ability to read a sentence with each eye suggests intact ophthalmic, neurologic and higher brain function. Facial muscles should have symmetry. Ears Look in her ears. While not always necessary, a quick look in the ears will confirm pearly-white drums, the absence of fluid behind the drum, clean canals and the absence of pain while pulling on the external ear to straighten the canal. Thyroid Check the thyroid gland. Many gynecologists routinely feel the thyroid for enlargement, tenderness or lumps, which might suggest a thyroid nodule. Lungs Listen for wheezes suggesting asthma, diminished breath sounds, or fine crackles, suggesting pneumonia or heart failure. Some apparently abnormal sounds will clear if the patient coughs. Heart Listen. Note the regularity of the rhythm, and the presence of any abnormal sounds such as clicks or murmurs. Breasts Check for any lumps, masses, tenderness, nipple discharge, or skin changes such as dimpling, retraction or crusting. Abdomen Palpate the abdomen. It should be soft, and non-tender, with no masses. The liver may be just barely palpable below the rib cage and should not be tender. Pelvic Examination Evaluate the pelvis systematically. Visually inspect the vulva, vagina and cervix. Obtain specimens for a Pap smear and any cultures that may be indicated. Then feel the pelvis by application of a "bimanual exam." For a normal examination: External genitalia are of normal appearance. There is no enlargement of the Bartholin or Skene glands. Urethra and bladder are non-tender. Vagina is clean, without lesions or discharge Cervix is smooth, without lesions. Motion of the cervix causes no pain. Uterus is normal size, shape, and contour. It is non-tender The adnexa (tubes and ovaries) are neither tender nor enlarged. Pap Smear Obtain a Pap smear annually. Sometimes, a Pap is repeated more often, particularly if there have been abnormalities on prior Pap smears. Cultures Cultures can sometimes be helpful in determining the cause for vaginal or vulvar symptoms such as pain, burning or itching. Bacterial cultures for Strept, E. coli and other pathogens may then indicate a course of treatment. Some physicians routinely culture for gonorrhea and/or chlamydia on all of their patients at each routine visit. Whether this is wise for you depends on the frequency with which these STDs are found in your population. Rectal While some physicians routinely perform a rectal exam on all patients, others perform a rectal only on selected individuals in certain clinical circumstances, such as after age 50. Routine screening with sigmoidoscopy every 5 years after age 50 is recommended by many physicians. After the rectal exam, the small particles of stool left on the examining glove can be evaluated for the presence of occult blood. This is most useful after the age of 50. Urine Some physicians routinely check the urine at each routine visit. Others check the urine only for specific indications. A clean urine specimen can be evaluated for the presence of: Color Character Leukocytes nitrite Urobilinogen Protein pH Blood Specific Gravity Ketones Bilirubin Glucose Wet Mount Vaginal discharge can be evaluated using a "wet mount." A small amount of discharge is mixed with 10% potassium hydroxide (KOH), placed on a glass slide and covered with a coverslip. The KOH dissolves cell membranes, making it easier to see yeast organisms under the microscope. Another small amount of discharge is mixed with a drop of normal saline, placed on a glass slide and examined under the microscope. With saline, active trichomonad organisms can be seen moving and "clue cells," indicating bacterial vaginosis can be seen. Mammography Mammography is a useful method of evaluating the breasts for the possible presence of early malignancy. While not 100% accurate, it is probably around 80% accurate, particularly in detecting the very small, early malignancies not appreciated by physical examination. Recommendations for frequency of mammograms, but the following general guidelines can be followed: Women with a disquieting symptom (eg bloody nipple discharge) or physical finding may benefit from an indicated mammogram Women with no significant high risk factors will probably benefit from routine mammogram screening every other year, from age 40 to 50, and annually after age 50. Women with a strong family history of breast cancer or other significant high risk factor may benefit from more frequent mammogram screening, and starting at a younger age. Breast Self-examination An important part of patient education is to see that she feels confident in her skills at self-breast examination. If not, you can teach her the proper techniques. I sometimes inquire: "Are you examining your breasts regularly?" Immunizations In the civilian population, adult immunizations generally include: dt (Tetanus) every 10 years Measles booster once if born in 1957 or thereafter Influenza for the high risk group (Yearly>65, those with significant medical risks and their close contacts) Pneumococcus once after age 65 or in any high risk group Hepatitis B for high risk groups In military populations, immunizations are directed by the Armed Forces Immunizations Program, and augmented by the addition of anthrax immunization. Counseling Counseling may be brief or lengthy. It may be focused on the problems presented during the examination, or may be global, such as diet, exercise, or other healthy life-styles. Patients often feel this is the most important part of the visit. Take your time and sit down while talking to the patient. You need not be a master of "bed side manner" for the patient to appreciate this time. Just be honest, direct, and pleasant. Plan Before leaving, the patient should understand any future plans. Laboratory requisitions or consultation requests can be given. Patient hand-outs can be provided. Plans might include: Mammography Laboratory tests Consultations Patient information brochures It is routine to indicate when the patient should return to the office (RTO) or return to the clinic (RTC). "RTO in _______ months." Pap Smears The Cervix The cervix is located at the top of the vagina. It is the opening to the uterus and is composed of dense connective tissue. It has very little smooth muscle in it, compared to the rest of the uterus, which is almost entirely smooth muscle. The cervix is visualized by placing a speculum in the vagina. At the top of the vagina is a smooth, pink, firm structure with an opening (the os) in the center, which leads to the uterus. The Pap Smear In the 1940's, Dr. Papanicolaou developed a technique for sampling the cells of the cervix (Pap smear) to screen patients for cancer of the cervix. This technique has proven to be very effective at not only detecting cancer, but the pre-cancerous, reversible changes that lead to cancer. While not originally designed to detect anything other than cancer, the Pap smear has proven useful in identifying other, unsuspected problems. So useful has the Pap smear become, it is considered an essential part of women's health care. It is typically performed annually in sexually-active women of childbearing age, although there are some important exceptions. Because the Pap smear is a screening test, it can have both false positive and false negative results. For this reason, it is important to have the test performed regularly (annually in the military services). It is not likely that the Pap smear will miss an important lesion time after time. Pap smears are best performed in a stable, garrison situation because of the time it takes to send out the smear, have it read, get the result back, and perform any follow-up care that is needed. The actual obtaining of a Pap smear can be done almost anywhere (at sea, in the air, in the field), but getting the results back and further treatment performed in these operational settings can be difficult or impossible. Position the Patient Position the patient with her buttocks just at the edge or just over the edge of the exam table. If she is not down far enough, inserting the speculum can be more difficult for you and uncomfortable for her. Appropriate draping should be used to help make the patient more comfortable but not to the point that it obstructs your view. Good lighting is important and is often accomplished with a goose-neck lamp. Field Expedient Exam Table In Field or other military situations, a conventional examination table may not be available and you will need to improvise. One method is to use a normal bed with the patient in frog-leg position and the buttocks elevated with a bedpan or folded blanket. A litter may be used with litter stands repositioned to better support the weight of the patient. IV poles serve as the upright portion of the stirrups. Small battle dressings looped over the IV pole and around the feet complete the stirrups. Note that the patient's legs are positioned outside the IV poles, not inside. A folded blanket can elevate the head and a second blanket can provide for draping. Stability of the litter is important. An assistant may be positioned at the opposite end of the litter for this purpose, or sandbags may be used. A packing crate can serve as a stool, but kneeling on the ground usually positions the examiners eyes at perineum level. Lighting needs to be the best allowed by the tactical circumstances. Good lighting can be obtained from a generator-supplied surgical lamp, flashlight, or natural sunlight with a mirror to direct the light into the vagina. At times, the tactical situation may only permit the light from a single red-filtered flashlight. Even with this restriction, a reasonably satisfactory examination may be possible. A tent, rigging of ponchos, or appropriate blankets should provide privacy. When these methods are not available, employing psychological or "virtual privacy" methods should be attempted. Pad the Stirrups Pad the stirrups so that they don't dig into the patient's foot. Oven mitts, socks, and even small or medium-sized battle dressings can be used to cushion the stirrup. Allowing the patient to keep her socks on will provide additional padding and help keep the patient's feet warm during the exam. Inspect the Vulva Gently spread the labia apart and inspect the vulva, looking for lesions, masses, drainage, or discolorations of the skin. Explain what you are doing to the patient to keep her relaxed. Warm the Speculum Warm the vaginal speculum. Running water works well for this as it also lubricates the speculum. Some health care providers use a heated drawer or heating pad to keep the speculums warm. Do not overheat as a speculum that is too hot is just as uncomfortable as one that is too cold. Never use K-Y Jelly(r), Surgilube(r), Petroleum Jelly or other lubricant to moisten the speculum as it will likely make your Pap smears unreadable under the microscope. Insert the Speculum After warming the speculum, separate the labia and keep them apart. Insert the speculum into the vagina, letting the speculum follow the path of least resistance. Some vaginas go straight back, parallel to the floor. Other vaginas tilt slightly downward toward the floor as the speculum advances. Others angle upward, away from the floor. Keep the speculum blades closed until the speculum is completely inserted. Open the speculum and usually the cervix is immediately visible. If not, the cervix is usually just below the lower blade or just above the upper blade. Rocking the speculum downward and upward usually causes the hidden cervix to drop into view. Lock the blades in the open position, wide enough apart to allow complete visualization of the cervix but not too far open as to be uncomfortable for the patient. With practice, insertion of the speculum should generally be painless. Field Expedient Speculum In a field environment, a standard vaginal speculum may not be available. Several good solutions are available. Standard GI issue spoons can be bent at a 45-degree angle to create the equivalent of a Sims or right-angle retractor. Two of these bent spoons can be gently inserted, one at a time, into the vagina, after warming and lubricating with warm water. An assistant supports these retractors while the provider manipulates them to expose the vaginal walls and cervix. Positioning one spoon posteriorly and the other spoon anteriorly seems to work the best in the majority of cases. For patients in whom the spoons are too large to comfortably fit inside the vagina, the spoon can be reversed, using the handle as the vaginal wall retractor and the spoon end as a handle. Alternatively, two GI spoons can be bent less severely and connected at the center with a rubber band. At rest, the rubber band holds the spoons apart to expose the vagina and cervix, but for insertion, the spoon handles are separated, closing the spoon ends. After insertion, the spoon handles must be shifted to one side or the other to obtain good visualization to the vagina and access for instruments. Optimally, these retractor and speculum substitutes should be sterilized before use. Ordinarily, this would require an autoclave, packaging, heat sensitive tape, and control tests. In a military environment, these may not be available but placing the spoons in boiling water for 10 to 15 minutes is a reasonable substitute. If the tactical situation does not allow for any sterilization, clean instruments are much better than dirty instruments. Start with the Spatula The Ayer spatula is specially designed for obtaining Pap smears. The concave end (curving inward) fits against the cervix, while the convex end (curving outward) is used for scraping vaginal lesions or sampling the "vaginal pool," the collection of vaginal secretions just below the cervix. The spatula is made of either wood or plastic. Both give very satisfactory results. Rotate the Spatula The concave end of the spatula is placed against the cervix and rotated in circular fashion so that the entire area around the cervical opening (os) is sampled. Usually this can be done without causing any discomfort, although some women are sensitive to the sensation and may experience minor cramping. Sometimes, obtaining this sample causes some bleeding. In this case, reassure the patient that: although she may have some minor bleeding or spotting for a few hours, it is not dangerous, it will stop spontaneously and promptly it is caused by the Pap smear.  Sample the SQJ In obtaining the Pap smear, it is important to sample the "Squamo-columnar Junction." This is the circular area right at the opening of the cervix where the pink, smooth skin of the cervix meets the fiery-red, fragile, mucous-producing lining of the cervical canal. If there is a problem with cancer or precancerous changes, it is this area that is most likely to be effected. This area of unstable skin is also known as the SQJ, or transition zone. Make a Thin Smear Spread the sample taken from the cervix on a glass slide. Try to make the smear as thin as possible since this makes it easier for the pathologist or cytotechnician to read. Make sure the slide is labeled (using pencil on the frosted end). In your zeal to make a thin slide, don't spend too much time or else the slide will dry, making it harder for the cytotechnician to read. Spray Immediately Immediately spray the glass slide with cytological fixative. If the slide is not immediately sprayed (within about 10-15 seconds), the smear will dry out, making interpretation more difficult or impossible. If cytological spray is unavailable, any material that has a significant amount of acetone in it can be a reasonably good substitute. Hair spray works well. Next Use a Brush Use a "Cytobrush" to sample the endocervical canal, the inside of the opening leading into the uterine cavity. These soft brushes are designed to be inserted into the canal without causing damage. Insert and Rotate 180 Degrees Push the cytobrush into the canal, no deeper than the length of the brush (1.5 cm - 2.0 cm). Rotate the brush 180 degrees (half a circle) and pull the cytobrush straight out. Don't keep spinning the brush round and round or you will cause bleeding. Even the 180 degree rotation may cause a little bleeding but usually it doesn't. Smear the sample on another slide, spreading the material evenly over the slide. Spray with fixative immediately. Allow the slides to dry completely before placing them in the Pap smear container. Once dry and packaged, it is best to send them out promptly for interpretation. When operational circumstances disallow prompt sending of the slides, they can be held for weeks to months without significant loss of readability. Make sure the slides are properly labeled and that important clinical information is included with the requisition. Telling the cytologist that the patient has had a hysterectomy will save considerable amounts of time in evaluating the smear. For women who have had a hysterectomy, Pap smears are obtained by using the convex end of the Ayerza spatula, scraping it horizontally across the top of the vagina. Then the cytobrush is used to reach into the right and left top corners of the vagina. This outline of Pap smears describes a "two-slide" technique. Often, only a single glass slide is used (a "one-slide" technique). Using only a single slide, the Ayer spatula is smeared over one end of the slide and the cytobrush is smeared over the other end. It is fine if there is overlap between the two areas and it doesn't matter which smear is placed on which end of the slide. Dysplasia Dysplasia means that the skin of the cervix is growing faster than it should. Cervical skin cells are produced at the bottom of the skin (basal layer). As they reproduce, the daughter cells are pushed up towards the surface of the skin. As they rise through the skin layer, they mature, becoming flat and pancake-like (as opposed to round and plump). Their nuclei initially become larger and darker. If these daughter cells reach the surface of the skin before they are fully mature, a Pap smear will reveal some immature cells and "dysplasia" is said to exist. There are degrees of dysplasia: mild, moderate, and severe. None of this is cancer, but the next step beyond severe dysplasia is invasive cancer of the cervix. For this reason, any degree of dysplasia is of some concern, but the more advanced the dysplasia, the greater the concern. Mild Dysplasia Mild dysplasia means the skin cells of the cervix are reproducing slightly more quickly than normal. The cells are slightly more plump than they should be and have larger, darker nuclei. This is not cancer, but does have some pre-malignant potential in some women. Other phrases that describe mild dysplasia include: LGSIL (Low-grade Squamous Intraepithelial Lesion) CIN I (Cervical Intraepithelial Neoplasia, Grade 1) Many factors contribute the development of mild dysplasia, but infection with HPV, (Human Papilloma Virus) is probably the most important. Smoking tobacco products and an impaired immune system also may contribute to this. Mild dysplasia can come and go, being present on a woman's cervix (and Pap smear) at one time and not another. Of all women who develop mild dysplasia of the cervix, about 10% will, if untreated, slowly progress through the various degrees of dysplasia and ultimately develop invasive cancer of the cervix. The rest will either remain unchanged or regress back to normal. Because so many cases of mild dysplasia regress, It is common for women who develop a single Pap smear showing mild dysplasia to be watched over time with the Pap smear being repeated in 6 months. If the dysplasia persists or worsens, further evaluation is undertaken. If the Pap returns to normal, the woman's cervix is followed, sometimes with more frequent Pap smears. Other physicians feel that the cervix should be evaluated with colposcopy with even a single dysplastic Pap smear. Their reasoning is that while many of the Pap smears revert to normal in 6 months, the abnormality will often re-appear at a later, less convenient time. They also reason that many women will feel anxiety over simply observing the abnormality over time and not investigating it right away. Operational circumstances may well dictate the approach that needs to be followed. For women who have previously been evaluated with colposcopy and found to have dysplasia, the appearance of mild dysplasia on a subsequent Pap smear is not particularly alarming. Whether to re-colposcope them and the timing of such a re-evaluation must be individualized, based on the operational circumstances, the patient's history, risk factors, the degree of abnormality in the past and intervening Pap smear results. It is best to consult with an experienced colposcopist or gynecologist before making a final decision. Treatment of mild dysplasia may be cryosurgery (freezing the part of the cervix containing the dysplastic cells and destroying those cells). Other approaches include vaporizing the dysplastic cells with a laser, or shaving them off with an electrified wire (LEEP). Sometimes, the mild dysplasia is not treated at all, but the patient is closely watched instead. If the dysplasia advances to a more severe stage, treatment can be undertaken at that later time. But for women in low-risk situations whose cervical lesion does not advance, surgery can sometimes be avoided. Moderate Dysplasia Moderate dysplasia means the skin of the cervix is growing faster than it should and has progressed beyond the mild stage. A biopsy of the cervix would show immature basal cells growing partway through to the surface of the skin, without significant maturation. Moderate dysplasia is important because there is a much greater risk that these changes will advance, if untreated, into invasive cervical cancer. For that reason, moderate dysplasia is known as a "high grade" lesion, or "high grade squamous intra-epithelial lesion" (HGSIL). Another synonym for this condition is "CIN II" (Cervical Intra-epithelial Neoplasia Grade II). Moderate dysplasia on a Pap smear usually indicates that further study of the cervix with colposcopy is needed. If moderate dysplasia is confirmed, then it is usually treated. Treatments might include cryosurgery, LEEP, or laser. Following treatment, frequent Pap smears are usually obtained as follow-up to make sure that if there is a recurrence (about 10% chance), that the recurrence is promptly diagnosed and further treatment performed. Severe Dysplasia Severe dysplasia means that the skin of the cervix is growing so rapidly that the immature basal cells extend completely through the skin thickness to the surface with any maturation. This is evidenced on the Pap smear as many completely immature cells appearing on the slide. This condition, a high grade intraepithelial problem, is also known as "CIN III." (Cervical Intraepithelial Neoplasia, Grade III), or "carcinoma-in-situ." This is not cancer, but the only reason it isn't cancer is because the immature cells have not started growing (invading) beneath the epithelium into the underlying tissues. Because it is only one step away from invasive cancer, this is a very dangerous condition requiring treatment. Treatment might consist of eliminating the dysplastic cells by freezing them (cryosurgery), vaporizing them (laser), or shaving them off with an electrified wire loop (LEEP). In some circumstances, more extensive surgery in the form of a cervical cone biopsy is required to eliminate the problem. Carcinoma in situ This is not cancer, but is considered a pre-cancerous problem. Carcinoma in situ means: There are abnormal cells extending the full thickness of the skin. These cells individually look just like cancer cells. If the cells were invading through the basement membrane into the underlying tissues, they would be considered cancer. Because they have not invaded through the basement membrane, they are, by definition, not cancer. Carcinoma in situ is considered by many authorities to be clinically equivalent to severe dysplasia, or CIN III. A qualified health care provider should promptly and carefully evaluate it. Treatment might consist of eliminating the abnormal cells by freezing them (cryosurgery), vaporizing them (laser), or shaving them off with an electrified wire loop (LEEP). In some circumstances, more extensive surgery in the form of a cervical cone biopsy is required to eliminate the problem. Hysterectomy is generally not necessary, but under unusual circumstances might be the best choice for treatment. Invasive Cancer of the Cervix Cancer of the cervix is among the more common forms of cancer affecting the reproductive organs. It is locally invasive into neighboring tissues, blood vessels, lymph channels and lymph nodes. In its' advanced stages it can be difficult to treat and may prove fatal. Prior to developing cancer of the cervix, there is usually a period of pre-cancerous (and reversible) change, known as dysplasia. This can be detected by Pap smears, and is the basis for periodic screening with Pap smears. Depending on the stage or degree of invasion, cancer of the cervix may be treated with local excision, hysterectomy, radical hysterectomy, radiation, and chemotherapy. Adenocarcinoma of the Cervix While most cancer of the cervix comes from the squamous cells making up the exterior skin, there is an occasional cancer that arises from the mucous-producing cells which line the endocervical canal leading up into the uterus. This is called "adenocarcinoma" as opposed to "squamous cell carcinoma." Because adenocarcinoma may not appear on the Pap smear if just a spatula is used, the brush part of the Pap smear is particularly important. It is the brushing of the endocervical canal which is most likely to detect the presence of adenocarcinoma of the cervix. Visible Lesions on the Cervix Whenever a visible lesion or abnormality is seen on the cervix that cannot be positively identified visually, it should be biopsied. Waiting for the results of a Pap smear and obtaining a biopsy only if the Pap is abnormal can be a mistake, since the Pap smear is only a screening test and has both false positives and false negatives. Even in the presence of gross cancer of the cervix, a Pap smear may occasionally be falsely reassuring. If there is a visible abnormality that you cannot identify as innocent, biopsy is usually the wisest course Colposcopy A technique of viewing the cervix to determine the source of abnormal cells. It consists of: Soaking the cervix with vinegar (acetic acid). Looking with binocular magnification (6-10x). Using a red-free light (blue or green). ...and frequently... Taking small biopsies of the cervix. Colposcopy is the first step in the evaluation of significant abnormalities on a Pap smear. It may be recommended by the cytologist after reviewing a Pap for which there are some significant clinical concerns. Actinomycosis This fungus is occasionally identified on Pap smear and for the most part is an incidental finding, posing no threat to the patient. Its' clinical significance controversial. IUD users sometimes (rarely) develop pelvic abscesses with this organism inside. For that reason, some physicians have recommended removal of the IUD in asymptomatic patients if Actinomyces are present. Others disagree, believing that removal of the IUD in patients with no symptoms is an over-reaction to a very small chance of a problem. AGUS Atypical glandular cells of undetermined significance (AGUS) is an abnormality similar, in some respects, to ASCUS. However, AGUS is associated with about a 50% rate of significant cervical abnormality, including high grade changes, squamous cell carcinoma and adenocarcinoma. While AGUS can be carefully watched over a period of time to see if it persists prior to evaluation with colposcopy, many physicians proceed directly to colposcopy because of the relatively high yield of significant abnormalities. Atrophy This is an expected finding in menopausal women not taking estrogen replacement therapy. If this is the only abnormal finding and the patient has no symptoms, it can be safely ignored. If the patient complains of vaginal dryness, irritation, painful intercourse, vaginal discharge, odor, or other symptoms, then the Pap finding of atrophic vaginitis is helpful in determining the cause. If the Pap smear has other abnormalities, treating the patient for 2-3 weeks with Premarin 0.625 mg PO daily and then repeating the Pap will often result in the other abnormality disappearing. ASCUS ASCUS (Atypical Squamous Cells of Undetermined Significance) is the way the cytologist tells you that there is something on the patient's Pap smear that is not perfectly normal, but they can't tell with any certainty what it is or whether it is significant. ASCUS smears are handled differently in different circumstances: If this is the first time any abnormality has been found on the patient's Pap smears, some gynecologists recommend colposcopy, while others recommend simply treating any coincidental infection (if present) and repeating the Pap in 6 months. Should the abnormality persist, then colposcopy is usually recommended. If the patient has previously been evaluated for an abnormal Pap and found to have either mild dysplasia or HPV changes, the occurrence of an occasional ASCUS smear is not surprising and is often considered normal for that person. In higher risk circumstances, further colposcopy is sometimes undertaken to re-evaluate the cervix. A patient with (1) a past history of cervical dysplasia, who (2) has had many normal Pap smears following treatment, and who (3) develops ASCUS should probably be re-evaluated colposcopically if she has not had that procedure done recently, as this could represent the beginning of a new problem. Usually, evaluation of an ASCUS smear is not an emergency and can await completion of operational commitments. Candida (Monilia, Yeast) This fungus is occasionally identified on Pap smear and for the most part is an incidental finding, posing no threat to the patient. If the patient is experiencing symptoms (itching, burning, or cheesy discharge), then she should be treated for a yeast infection. If the Pap smear shows... Significant inflammation, or Reactive changes, or Reparative changes, or Class II or Class IIA category, or ...then some physicians favor treating the yeast infection (which makes the Pap smear easier to read) and then following up with another Pap smear. Other physicians feel that is not necessary so long as the patient continues to come in annually for a Pap smear. Any abnormality not seen because of an obscuring yeast infection, they reason, will be seen at the next Pap smear. If you are preparing to investigate a more serious abnormality with colposcopy, then it is probably worthwhile treating the yeast to try to reduce the confusing picture of inflammation that may be present. If the Pap smear is otherwise normal and the patient without symptoms, Candida appearing on the Pap smear can be safely ignored and the Pap repeated, as usual, in 1 year. Chlamydia Chlamydia is a common sexually-transmitted illness. It can be found in 5-20% of asymptomatic women, depending on their sexual history. In the majority of cases, it causes no problems, but in some patients, it causes: PID (pelvic inflammatory disease) Infertility Cervicitis Whenever chlamydia is suggested on a Pap smear, consider one of the following approaches: Assume chlamydia is present, treat with Doxycycline (or erythromycin or Azithromycin), and then perform a chlamydia culture to insure it has been eradicated, or Bring the patient in for a chlamydia culture. If positive, treat with Doxycycline (or erythromycin or Azithromycin). If negative, ignore. CIN CIN (Cervical Intraepithelial Neoplasia) is an older term that describes the process of dysplasia. There are degrees of CIN: CIN I is equivalent to mild dysplasia and low grade SIL (Squamous Intraepithelial Lesion) CIN II is equivalent to moderate dysplasia and represents a high grade SIL CIN III is equivalent to severe dysplasia, carcinoma-in-situ, and is a high grade SIL. Coccoid Bacteria The presence of these bacteria on an otherwise normal Pap smear is of no consequence. If the Pap shows inflammation sufficient to obscure the reading and the cytologist asks for an earlier-than-normal repeat Pap, many physicians will treat the patient with a broad-spectrum antibiotic suitable for strep and anaerobic bacteria (Flagyl, Amoxicillin, etc.) before repeating the smear. Others will simply repeat the smear at a somewhat earlier than normal time. If the Pap is otherwise normal, but the patient complains of symptoms of vaginal discharge, bad odor or irritation, the presence of coccoid bacteria on the Pap smear is sometimes used as the basis for treatment using broad-spectrum antibiotics effective against strep and anaerobes. In the absence of symptoms or other abnormality on the Pap, the presence of coccoid bacteria is not considered clinically significant and needs no treatment. Condyloma An abnormality in the appearance of the cells of the skin of the cervix which suggests the presence of condyloma (venereal warts). Condyloma are not by themselves dangerous, but require further investigation, because: Condyloma are caused by HPV, the same virus which is associated with cervical dysplasia and cancer of the cervix. The Pap changes which suggest condyloma have basically the same clinical significance as the changes suggesting low grade intraepithelial lesions (LGSIL), CIN I, and mild dysplasia. Patients demonstrating condyloma on their Pap smears who previously had normal Paps are ideally evaluated with colposcopy and cervical biopsies to determine the precise diagnosis, extent of the problem, and rule out other, more significant illness. If operational requirements make prompt evaluation difficult or dangerous, colposcopy can usually be safely delayed for weeks to a few months. Drying Artifact The Pap smear must be sprayed with cytology fixative immediately (within seconds) of spreading the smear on the glass slide. The slide should be soaked so that the fixative will begin to fall off the slide if it is tilted (don't tilt it to see as you may lose some cells). Many physicians avoid the problem of drying by leaving the speculum in place while they obtain their specimen, spread it on the slide and immediately fix it with spray. If you are temporarily out of cytologic fixative, hair-spray is an acceptable alternative. Endocervical Cells not Present The presence of endocervical cells on a Pap smear is an indication that the smear included sampling of the cervical canal and, by inference, the squamo-columnar junction. If endocervical cells are not seen, it may mean: You did not sample high enough in the cervical canal. Your sampling was fine, but the cytologist didn't recognize the cells. Some physicians feel that any Pap without endocervical cells should be repeated. However, studies have demonstrated that Paps without endocervical cells are still very effective in detecting abnormalities. Pap smears obtained at a 6-week postpartum visit often do not have endocervical cells present. If your Pap smears consistently show "no endocervical cells," you may wish to review your basic Pap smear technique to be sure you are taking a high enough sample. Endometrial Cells are Present This indicates that endometrial cells, normally located inside the uterus, have been shed and are appearing at the mouth of the cervix. This is a normal finding in women of childbearing age, particularly if they are close to starting or just finishing their menstrual period. Menopausal women taking estrogen replacement therapy may also normally show a few endometrial cells on their Pap smears from time to time. In menopausal women not taking estrogen replacement therapy, the presence of endometrial cells is an abnormal finding and should be followed up with an endometrial biopsy to try to determine the reason for the presence of these cells. Estrogen Effect Estrogen has a predictable effect on the cells of the cervix and the absence or presence of estrogen can be determined on the Pap smear. In women of childbearing age, or menopausal women taking estrogen replacement therapy, the Pap would be expected to show an "estrogen effect," and its' absence would be a curiosity, though probably not dangerous. In menopausal women not taking estrogen replacement therapy, the presence of detectable "estrogen effect" would suggest some non-ovarian source of estrogen and the long-term effects of unopposed estrogen should be considered. Gardnerella The presence of Gardnerella on an otherwise normal Pap smear in a patient without symptoms is of no consequence. If the Pap shows inflammation sufficient to obscure the reading and the cytologist asks for an earlier-than-normal repeat Pap, many physicians will treat the patient with Flagyl before repeating the smear. Others will simply repeat the smear at a somewhat earlier-than-normal time. Herpes If the Pap smear demonstrates giant cells with intranuclear inclusions, the cytologist may report "possible herpes virus." In the asymptomatic patient with an otherwise normal Pap smear, this is of no clinical significance. Some physicians will bring the patient back for a herpes culture (if her history is negative for herpes), while others will ignore this finding. If the Pap shows significant degrees of inflammation, the presence of herpes virus may explain the inflammation. A follow-up Pap avoiding any time of herpes recurrence may give more reliable information. In patients suspected of having herpes, a herpes culture is ideal for confirming the diagnosis. If such a culture is unavailable, scraping an active lesion and preparing a Pap smear from the secretions can be useful. In this case, the cytologist looks carefully for herpes-related microscopic findings. HPV An abnormality in the appearance of the cells of the skin of the cervix which suggests but does not confirm the presence of human papilloma virus (HPV). This finding is often based on the presence of "koilocytes," having enlarged nuclei, surrounded by a clear "halo" of cytoplasm. Koilocytes often (but not invariably) point to the presence of virus in the cells. Patients demonstrating these changes who previously had normal Paps are ideally evaluated with colposcopy and cervical biopsies to determine the presence or absence of HPV, although such evaluation can usually safely wait for weeks to a few months if necessary because of operational requirements. Inadequate Smear This means the quality of the Pap smear is not adequate to give a reliable interpretation. The smear may be inadequate because: An insufficient number of cells were present. The slide had too many RBCs on it. The slide had too many WBCs on it. The cells had dried out before fixative was applied to the slide. An inadequate smear should be repeated, using good technique and fixing the slide with appropriate spray immediately after the cells are smeared on the glass. Before repeating the Pap, you may want to treat any infection that is present (to eliminate the WBCs) and make sure the patient is not on her period (to eliminate the RBCs). Inconclusive Smear This usually means that there are either too few cells to be certain of the diagnosis, or there are confusing findings and the cytologist is warning you not to rely too strongly on this smear. t is wise to repeat "inconclusive" smears. Before repeating the Pap, treat any infection that may be present, avoid her menstrual flow, get a good, representative sample, and apply the fixative immediately. When repeating an "inconclusive" Pap, it is sometimes helpful to the cytologist to obtain two slides rather than one, just to provide more material for review. Inflammation Inflammation merely means the cervix is irritated for some reason. In the absence of any symptoms or any other significant abnormality on the Pap, it can be safely ignored. If inflammation is severe enough, it may interfere with the ability of the cytologist to accurately read the Pap. In such cases, it is wise to repeat the Pap at more frequent intervals (6-9 months) rather than the usual once a year. Inflammation by itself need not be treated. If other abnormalities are identified in addition to the inflammation, you may treat the other problems and the inflammation will probably go away. IUD Changes These are minor changes seen on the Pap smears of some women with IUDs. It is of no clinical significance. Koilocytosis A distinctive abnormality in the appearance of the cells of the skin of the cervix, in which some of the nuclei are surrounded by tiny "halos." Most commonly, these changes occur in the presence of HPV (Human Papilloma Virus) but occasionally are associated with more serious problems such a cervical dysplasia or even early malignancy. Patients demonstrating koilocytosis who previously had normal Paps are ideally evaluated with colposcopy and cervical biopsies to determine the source of the koilocytes, although such evaluation can usually safely wait for weeks to a few months if necessary because of operational requirements. Leptothrix This curious bacteria is occasionally found in large numbers in the vagina and cervix. t apparently causes no harm and is not considered a pathogen. It would not be worth noting except for two characteristics: It can live comfortably with Trichomonas. It can resemble yeast on a wet mount. It may safely be ignored. Nuclear Atypia An abnormality in the appearance of the nuclei of the cells of the skin of the cervix. Most commonly, these changes occur in the presence of HPV (Human Papilloma Virus) but occasionally are associated with more serious problems such a cervical dysplasia or even early malignancy. Patients demonstrating nuclear atypia who previously had normal Paps are ideally evaluated with colposcopy and cervical biopsies to determine the source of the atypia, although such evaluation can usually safely wait for weeks to a few months if necessary because of operational requirements. Reparative or Reactive Changes Changes in the skin cells of the cervix which suggest that a healing process is underway or that the cervix is reacting to the presence of a virus or bacteria. While these changes are not dangerous, their presence often provokes gynecologists to repeat the Pap smear at a sooner-than-expected time (such as 6 months, rather than 1 year after the previous Pap). The reasons for this increased surveillance are: Reactive or Reparative changes make the Pap more difficult to interpret, so that the clinician cannot be as reassured by this Pap as he/she would by a Pap without these changes, and Distinguishing between reactive/reparative changes and early dysplasia is difficult and the Pap interpretation may be incorrect. Other gynecologists feel that in a patient with previously normal Pap smears, the first appearance of reactive/reparative changes is not cause for alarm and they will repeat the Pap at the next annual examination. They reason that should there be an underlying dysplastic process, the progression of dysplasia is usually so slow that there is no particular advantage to repeating the smear sooner than the annual exam. SIL This is a general term for dysplasia. Low grade SIL (LGSIL) includes mild dysplasia, HPV changesHYPERLINK \l "HPV", and CIN I. These are considered "low grade" because the risk of progression to malignancy is small (10% or less). High grade SIL (HGSIL) includes moderate dysplasia, severe dysplasia, carcinoma in situ, CIN II and CIN III. These are considered "high grade" because many of them (although not all) will progress ultimately to invasive cancer of the cervix if not treated. Squamous Metaplasia This is an innocent finding that represents the normal squamous epithelium of the face of the cervix overgrowing the columnar epithelium of the cervical canal. Squamous metaplasia need not be treated. Trichomonas This microorganism is usually treated when identified on Pap smear. Trichomonas causes substantial inflammation of the cervix and makes the job of interpreting the Pap smear more difficult. After treating the patient with Flagyl, the smear should be repeated in about 3-6 months...long enough to allow complete resolution of any lingering inflammation, but sooner than 1 year. If there is other evidence of a significant cervical lesion (dysplasia) then the Pap may be repeated sooner after treatment. Birth Control Pills Benefits of BCPs BCPs provide highly reliable contraceptive protection, exceeding 99%. Even when imperfect use (skipping an occasional pill) is considered, the BCPs are still very effective in preventing pregnancy. In addition to their contraceptive benefits, the BCPs have a number of other benefits. BCPs generally: Cause menstrual cycles to occur regularly and predictably Shorten menstrual flows Lighten menstrual flows Reduce the risk of iron deficiency anemia Reduce menstrual cramps Eliminate painful ovulation Reduce premenstrual symptoms Reduce cyclic breast pain Improve acne Reduce the risk of ovarian cysts Reduce the risk of ovarian cancer Reduce the risk of uterine cancer Reduce the risk of uterine fibroid tumors Reduce the risk of symptomatic endometriosis Reduce the risk of pelvic inflammatory disease Reduce the risk of benign breast disease Risks of BCPs Aside from a number of minor, but annoying, side effects, serious risks of BCPs are limited, for the most part, to cardiovascular problems, including stroke, heart attack, thrombophlebitis and thromboembolism. These complications are very rare among women under age 35 who are non-smokers, and the added risk of BCPs is difficult to measure and probably insignificant. For non-smokers over age 35, the increased risk of cardiovascular problems among BCP users is measurable, but extremely small and certainly less than the risk of pregnancy. For smokers under age 35, the increased risk of cardiovascular problems among BCP users is measurable, but extremely small and certainly less than the risk of pregnancy. For smokers over age 35, the increased risk of cardiovascular problems among BCP users is very significant, and so high as to make such use ill-advised in any but the most extraordinary circumstances. There is also a very small, but measurable increase in the risk of liver tumors and cysts. The incidence of such problems in the population is so small and the added risk so marginal that only rarely will this risk play a role in the clinical decision for or against BCPs . Which Pill to Start Pick any standard, low-dose birth control pill that is readily available. Most women (90%) will do well on any low-dose BCP. A few will do well only on certain BCPs, but there is no way to predict in advance which pill will work best for any individual woman. Historically, as the hormone dose of birth control pills was lowered, the risk of serious complications such as blood clots was also reduced. For that reason, starting a low-dose pill (30-35 mcg of estrogen) is preferable to starting medium dose (50 mcg) or high dose BCPs. Lowering the dose below the 30-35 mcg dose has not, however, led to any additional clinical benefits but has made some of the very-low-dose pills more "unforgiving" than the standard low-dose BCPs. Starting the Pill Take the first pill on the first Sunday following the beginning of the menstrual flow. This means that if a period starts on a Tuesday, you should wait all the way through the week until Sunday, and then start taking the BCPs. If the period starts on a Saturday, then the first BCP would be taken the next day, Sunday. If the period starts on a Sunday, take the BCPs the same day. This method is called a "Sunday Start" and has a number of advantages. Because a fresh pill pack is always started on Sunday, it is easier for some people to remember. Using a "Sunday Start" means that the pill-induced periods will usually begin early in the week (Monday or Tuesday) and will be over before the weekend. Many women find this timing convenient and desirable. An alternative method ("5th Day") is to always start the BCP pack on day #5 of the menstrual cycle. Day #1 is the first day of flow. This method is very effective but requires counting and recalculations each month. When are the Pills Effective? The pills are reasonably effective right away. Some physicians recommend that women use a back-up method of contraception (such as condoms) during the first month of BCP use. This is based on the observation that BCPs probably do not achieve their 99.9% effectiveness until after the first month of use. It is also true that the BCPs are pretty effective, even starting with the first BCP. Many BCP manufacturers suggest that the BCP is effective after 7 days of continuous use. Even before 7 days of BCPs have been taken, considering that phase of the menstrual cycle, pregnancy is not very likely. For these reasons, the BCPs are probably about as effective as using a diaphragm (~85%-95% effective) as soon as they are started. For women seeking a higher level of protection against pregnancy (99.9%), using a backup method of contraception during the first month of BCP use may be considered. Skipped a Pill If she just skipped one pill, she should take it as soon as she remembers, then continue the rest of the pills at the normal time. If she didn't remember until the next day, take both the current day's pill and yesterday's pill together. Then continue with the rest of the pills in the usual way. If she's forgotten two pills or more, stop the BCPs, wait a few days for a "withdrawal" menstrual flow, and then restart a fresh package of BCPs 5 days after the onset of flow. Use backup contraception during this time and for the first month after restarting the BCPs. History of Migraine Headaches A history of migraine headaches is not a contra-indication to taking birth control pills. Some women with migraine headaches find they have fewer headaches while taking BCPs. This is particularly true for those women whose headaches primarily occur with ovulation or around the time of the menstrual flow. Other women with migraine headaches find the BCPs have no noticeable effect on their headache frequency or severity. These women may safely take BCPs. Those women who experience worsening of their migraine headaches should not be continue the same BCP. Switching to a different pill, with different content, from a different manufacturer, may solve the problem. If not, it will generally be necessary to stop the BCP completely. High Blood Pressure The birth control pill may be safely prescribed to women with pre-existing high blood pressure, but it is important for many reasons that the blood pressure be monitored and well-controlled. BCPs occasionally aggravate pre-existing high blood pressure. If this happens, switching to a different pill will sometimes solve the problem. If switching fails to resolve the problem, then usually the BCP will need to be stopped. BCPs will rarely cause a woman with normal blood pressure to become hypertensive. If this happens, switching to a different pill manufacturer will often solve the problem, but if not, the BCP is usually stopped. Diabetes The birth control pill may be safely taken by women with either a personal history or family history of diabetes melitus. Women who have diabetes often find taking BCPs has either no effect on their diabetic control or else improves their control. Some women find they need more insulin while taking BCPs, but are otherwise satisfied with the pill and these women may safely take it. A few women find their diabetic control is adversely affected by the BCP. For those women, changing the pill may be tried, but often the BCP must be discontinued. men with a family history of diabetes generally have no trouble taking BCPs. Very rarely, the BCPs may provoke diabetes (or unmask it). If this happens, alternative BCPs may be tried but usually the BCPs will be discontinued Blood Clot History Women who have personally experienced such blood clot problems as deep-vein thrombophlebitis, pulmonary embolism, cerebrovascular accident (stroke) or heart attack should not, under ordinarily take birth control pills. Women who have a family history of such problems but who have not, personally, experienced the problems, may safely take BCPs. Non Availability of her Pill Switch her to a BCP that is available. This is frequently an issue in operational settings. Because medical resources are not unlimited in these situations, it is often necessary to switch to a different pill. Since most women (90%) will tolerate any BCP without difficulty, making a switch is usually uneventful and most women will not notice any difference. It is best to make the switch at the time the old pills would have been started (after the "off" week), but they can be switched at any time during the cycle. It is possible but not common that they will experience some of the side-effects of nausea, spotting or breast tenderness during the first month of the switch. After the first month of the switch, these symptoms generally disappear. Anticipate that some of these women will be reluctant to change pills, particularly if they have had good success with one pill for a long time or if they had difficulty finding a pill that worked well for them. Postponing a Period with BCPs If a woman is expected to have a menstrual period at a time that is inconvenient or troublesome from an operational standpoint, it is often possible to postpone the menstrual flow using BCPs. Usually, BCPs inhibit ovulation and menstrual periods occur among women taking BCPs only because the user stops taking the BCPs for a few days. The fall in hormone levels triggers an apparently "normal" menstrual flow. With that principle in mind, a woman's normal menstrual flow can often be postponed by starting BCPs within 5 days of the beginning of her last menstrual flow. When she comes to the end of a 21-day pack of BCPs, she goes immediately into the next pack of BCPs (skipping the "week off.") She then continues with the second pack until such time as it becomes convenient to have a menstrual flow. Stopping the pills at this time will provoke a normal flow about 3 days after stopping the pills. This use of pills will usually keep her from ovulating (and keep her from having a period at the normal time). It is safe and will not cause any other disruption to the menstrual flow. Postponing menstrual periods is a technique often used by women entering short-term operational settings when they do not wish to have a menstrual flow while operationally deployed. There are drawbacks, however, to this approach. While most women tolerate BCPs without side-effects, some women (~20%) will experience such side effects as breast tenderness, nausea and spotting. Most of these side effects will occur during the first month of BCP usage. So a woman who takes BCPs for 6 weeks to postpone a menstrual period may be substituting one nuisance (menses at an inopportune time) for another nuisance (nausea, breast tenderness, spotting). One way to avoid these problems is to begin the BCPs well enough in advance of the operational commitment that any minor side effects have worn off. Another issue to consider is that while BCPs usually inhibit ovulation, they don't always inhibit ovulation. In other words, this menstrual-flow-postponing-protocol may not work, although it usually does. Choose a monophasic, standard low-dose BCP, such as LoOvral, Ortho Novum 1+35, LoEstrin 1.5/30 or similar pill when using it for this purpose. Avoid multiphasic pills and extremely low dose pills as their inhibition of ovulation is less reliable although they certainly are effective as far as contraception is concerned. Side Effects Most women (about 80%) experience no side effects while taking BCPs. The rest experience generally minor side-effects during the first month of BCPs. These side-effects might include breast tenderness, nausea, spotting or headaches, and generally disappear after the first month. If they persist, changing to a different pill, from a different manufacturer, with different hormonal content, will usually eliminate the problem. Occasionally, several pills will need to be tried before the best (least side effect for that individual person) is found. Very rarely, no satisfactory BCP can be found and those women will need to make a judgment whether they would rather continue the BCPs (with the side effect but with the BCP benefits) or to use an alternative method of contraception. Breast Tenderness Breast tenderness is relatively common during the first month of BCPs and uncommon thereafter. Persistent breast tenderness is most often associated with fibrocystic breasts. Typically, women with this condition notice the breast tenderness getting much worse just before menses and much better after the onset of flow. BCPs are a reasonably effective treatment for fibrocystic breasts so subsequent development of significant breast pain should be viewed as unusual. A careful breast exam should be done to rule out newly-developed breast disease. A recent onset of significant breast tenderness should raise your suspicions about a possible unsuspected pregnancy Nausea Nausea occurring after the 1st month or severe nausea at any time should make you suspicious of pregnancy, and this is usually ruled out by a negative pregnancy test or convincing patient history. Weight Gain As individuals age, there is a tendency to gain weight, with or without BCPs. It is difficult to show any significant additional weight gain in groups of women taking low-dose BCPs compared to groups of women (of the same age) not taking BCPs. That said, there are certainly individual women who gain weight when they take BCPs and lose the weight when they stop taking the BCPs. Similarly, there are individual women who lose weight while taking the BCPs and gain it back when they stop. Headaches While headaches can have many different causes, it is uncommon for the birth control pill to provoke headaches. Migraine headaches generally improve or stay the same on BCPs, but occasionally get worse. Premenstrual or menstrual headaches generally improve on BCPs, but occasionally get worse. If a woman complains of headaches only during the "off week" of BCPs, you can frequently resolve her headaches by modifying the way in which she takes her BCPs. These menstrual headaches are often provoked by the withdrawal of estrogen and progestin that accompanies the stopping of the BCPs at the end of each cycle. One way to resolve this problem is to shorten the "off week" from seven days to three days. The three days off is enough to provoke a menstrual flow, but about the time the hormone levels are low enough to provoke a headache, the woman restarts a fresh pack of BCPs. Another way to resolve this problem is to eliminate the "off week" entirely. A woman would go directly from one pack of pills into the next, skipping the placebo pills or the "off week." She won't have a menstrual flow and won't get menstrual headaches. After several months of this, she may experience some breakthrough bleeding which can be safely ignored if occasional. If she bleeds every day, then the BCPs can be stopped for 3 days to provoke a period and then restarted continuously for another few months. Medically, this is equivalent to taking the BCPs in the normal fashion, but avoids or minimizes the problem of menstrual headaches. If headaches persist on the BCPs and alternative formulations or dosage schedules fail to resolve the problem, the BCPs will generally be stopped. Moodiness or Depression Most cases of mood change are unrelated to the BCP use, but mood changes are a recognized potential side effect. In these cases, switching to a different BCP from a different manufacturer, with a different hormone formulation, will often resolve this problem. If the mood changes persist, it may be worthwhile to stop the BCPs for a month or two to see if this resolves the problem. Women with pre-existing depression, with or without anti-depression medication, can safely take BCPs, but should be monitored for signs of worsening of their depression. It is not healthy to remain moody or depressed for long periods of time, so this is an issue that clearly will need resolution one way or another. Vaginal Dryness Vaginal dryness or decreased lubrication during sexual activities is an uncommon but not rare side effect. This occurs when the BCP suppresses ovarian function (and natural estrogen production) but does not replace enough estrogen (from the BCP) to fully stimulate the vaginal and vulvar tissues. Women with this problem complain of vaginal dryness, irritation, sometimes painful intercourse and diminished lubrication during sex. Stopping the BCP will resolve this problem, but switching to a different pill from a different manufacturer may also resolve the problem. Adding additional estrogen (such as Premarin 0.625 daily) can also be effective, but long-term use may pose added cardiovascular risks such as is seen in the medium-dose or high-dose BCPs. "Personal Lubricants" can be used to overcome the problem, such as Lubrin, Replense, or KY Jelly. Decreased Libido (Sex-Drive) Some women notice diminished interest in sex while taking BCPs. Changing to a different BCP from a different manufacturer may resolve this problem, but some of these women find that no matter what brand of BCP they take, they experience this problem. There are many possible causes of decreased libido, including stress and relationship problems. To be certain the cause is the BCPs requires stopping the BCPs for a reasonable period of time (1-3 months) and seeing if the libido returns. Then, the BCPs are restarted to see if libido again changes. Painful Menstrual Cramps This is an unusual complaint for someone taking the birth control pill. Usually, BCPs make menstrual cramps better and many women find they have no cramps at all while taking BCPs. For someone to notice worsening of menstrual cramps while taking BCPs suggests that some other medical problem has developed, such as pelvic infection or endometriosis. In an operational environment, it is may be worthwhile to obtain cervical cultures for chlamydia and gonorrhea, but many physicians would give a course of antibiotics considering the varying degrees of reliability of such cultures and unusual nature of the symptoms in such circumstances. Good choices for antibiotics in this situation would include any of the following: Doxycycline 100 mg PO BID x 7 days Azithromycin 1 g orally in a single dose Erythromycin base 500 mg orally four times a day for 7 days Erythromycin ethylsuccinate 800 mg orally four times a day for 7 days Ofloxacin 300 mg orally twice a day for 7 days. Taking the BCPs continuously, without stopping for the off week can usually relieve the symptoms of menstrual cramps (dysmenorrhea) on BCPs. Whenever the operational commitment is complete, gynecologic consultation can be very useful to look for the many causes of cyclic pelvic pain. Continuous Birth Control Pills In some operational settings, it may be desirable to avoid menstrual flows completely. Depending on the tactical situation, changing sanitary pads or tampons can be difficult, distracting or dangerous. Women with significant menstrual symptoms (cramps, malaise, and depression) may find it easier to complete their mission if menstruation is avoided altogether. Normally, women take BCPs for 3 weeks and then stop the BCPs for a week. During the "off week," they have their menstrual period. The reason they have a menstrual flow at that particular time is because they stopped taking the BCPs. In other words, the menstrual flow is really a hormone withdrawal bleed. If they didn't stop taking their BCPs, they wouldn't have a period. Using this principle, a woman can go directly from one pack of pills into the next, skipping the "week off." She won't have a period. At the end of the second pack of pills, she can again go directly into the third pack, skipping the "week off' and skipping a menstrual flow. This way of taking BCPs is safe and just as effective in preventing pregnancy as taking them the normal way. The only drawback is that she loses the regular, monthly feedback of a menstrual flow, reassuring her that she is not pregnant. In practice, the BCPs are so powerfully effective that effectiveness is not really an issue. Should a woman become pregnant despite the use of BCPs (very, very rare), she will have other symptoms suggesting the pregnancy, including breast tenderness, fatigue, nausea, and bloating. In theory, women could use continuous BCPs indefinitely and never have a period so long as she continued taking the pills. Actually, there are two limiting factors to this approach. First, most women taking continuous BCPs will eventually experience some spotting or breakthrough bleeding. If it is mild and occasional, it is generally ignored. If it is daily or heavy, you can: Stop the BCPs for 3 days, provoking a period (withdrawal flow), and then resume continuous BCPs until the spotting once again becomes annoying. Add a small amount of estrogen (Premarin 0.625/day, Estrace 1.0/day, etc.) to each BCP. This additional estrogen will stimulate the uterine lining to become a little thicker and less fragile. Add any non-steroidal anti-inflammatory agents (NSAID) with significant anti-prostaglandin activity. This will reduce the force of the normal, physiologic uterine contractions and reduce or eliminate the spotting. Second, some women will occasionally experience a break-through ovulation, followed two weeks later by a menstrual flow. BCPs normally suppress ovulation, but their contraceptive effectiveness does not depend totally on ovulation inhibition. BCPs also change cervical mucous, fallopian tube motility, endometrial receptivity and doubtlessly has other effects. Particularly with low-dose BCPs, some women will ovulate anyway, although it is usually not noticed (when it occurs in phase with the BCP's), and pregnancy does not occur. For women taking continuous BCPs, any ovulation will inevitably be followed 2 weeks later by a full menstrual flow (whether she's taking BCPs or not), and such an event will certainly be noticed. If the woman taking continuous BCPs has a full-blown period, then it is wise to change to a different pill from a different manufacturer. Monophasic pills work better for this purpose than multiphasic pills. No Period or Very Light Period The heaviness of a menstrual flow depends on the thickness of the lining of the uterus just before the onset of menses. The thicker the lining, the heavier the flow. In women using low-dose BCPs (for example: Ortho Novum, LoOvral, Ovcon, etc.), there is a tendency for the uterine lining to become very thin, over the course of many months. Clinically, this is reflected as lighter and lighter periods, which may even stop completely. This is not a dangerous condition and will resolve if the BCPs are stopped. Stopping the BCPs is not necessary, however, because there are other safe alternatives. If the periods are simply very light (1-2 days), you can ignore the problem because this situation poses no threat to the patient. If periods have totally stopped: Rule out pregnancy. You may change to a different BCP with different hormone in it. This will often lead to recognizable periods because the different hormone is metabolized differently. You may add estrogen (Premarin .625 mg or Esterase 1 mg) to each BCP to increase the estrogen stimulation of the uterine lining, increasing its' thickness and leading to heavier periods. After the desired effect has been achieved (recognizable periods), the extra estrogen can be stopped. You may safely reassure the patient and allow her to remain without periods while taking the BCPs. As long as she otherwise feels well, the absence of periods while taking BCPs is not known to have any adverse effects and some women prefer to avoid monthly flows. Spotting Between Periods This symptom is common during the first month of BCPs, particularly with some of the multiphasic BCPs. This is not a dangerous condition, but may be a nuisance to the patient. In the presence of a normal Pap smear, this symptom can be safely ignored for two months and more likely than not, it will go away. If spotting persists, changing to fixed-dose, mono-phasic BCP (such as Ortho Novum 1/35 or LoOvral) will usually solve the problem, particularly if you switch to a different manufacturer. Occasionally, women spot even following this change and these women should stop the BCP briefly to make sure this symptom goes away. So long as the spotting disappears with discontinuation of the BCP, you can safely conclude that the spotting was due to the BCP and you may resume the BCP if you like. The spotting may return, but poses no threat. Other benign conditions can cause spotting, such as endocervical or endometrial polyps, cervical irritation, and uterine fibroid tumors, but none of these pose an immediate threat and can reasonably be ignored for months if necessary until definitive gynecologic consultation can be obtained. Uterine malignancy in a woman under 35 is extremely rare, particularly if that woman has been on BCPs. Spotting caused by uterine malignancy won't go away if BCPs are discontinued. A recent (within 1 year) normal Pap smear and the absence of a visible lesion on the cervix can reasonably exclude cervical malignancy. Vaginal cancer (extremely rare) is ruled out by a normal vaginal exam. Periods at the Wrong Time If a full menstrual flow occurs while the woman is taking her pills, this usually means she has ovulated despite the BCPs. This doesn't mean she will become pregnant, since the BCP has a number of ways of preventing pregnancy in addition to inhibiting ovulation, but it may increase slightly the statistical chance of pregnancy. If she continues to take the same BCP according to her usual routine, the BCP may, over the next month or two, achieve reasonable control over the menstrual cycle. Backup methods of contraception should be employed during this time. Alternatively, many gynecologists will stop the BCPs for 1-2 months to allow the woman's normal cycle to re-assert itself, and then resume BCPs (but from a different manufacturer, often using monophasic rather than multi-phasic BCPs) in step with the woman's own cycle. This means starting the BCP the 5th day after the beginning of flow, or alternatively, the first Sunday after the onset of the flow. Pregnancy may also cause bleeding during the pill cycle. Other causes for episodic abnormal bleeding include uterine fibroid tumors, uterine polyps, trauma and malignancy. A physical exam will reveal some of these but others will require more sophisticated gynecologic evaluation. Remember, uterine malignancy under age 35 is very rare and vaginal malignancy is extraordinarily rare. Cervical malignancy in the presence of a normal Pap smear is also very uncommon. If abnormal bleeding persists, gynecologic consultation will be necessary, but this can be safely accomplished within weeks to months so long as the: patient is not bleeding heavily and continuously examination is normal Pap smear is within 1 year patient is less than 35 years old Antibiotics When taking Birth Control Pills and antibiotics, it is generally not necessary to use any form of back-up contraception. Taking antibiotics may lead to altered intestinal flora and ultimately to changed levels of hormone in the patient's blood stream. This observation has led some authorities to suggest the use of back-up contraception, believing that the changed levels of hormone might diminish the effectiveness of the BCP. In controlled studies, this theory has not been proven, and in the case of tetracycline and chlortetracycline, no increased risk of pregnancy was found. If taking antibiotics has any effect at all on pregnancy rates, the effect must be very small and is not likely to have much clinical relevance in an operational setting. Thinks She May be Pregnant You should find out. BCPs are the most effective reversible method of contraception and failures are uncommon. Factors that increase the likelihood of failure would include skipping BCPs or taking an interfering drug. Pregnancies may rarely occur in women taking the BCP correctly. Any time any woman taking BCPs thinks she might be pregnant, get a sensitive pregnancy test. Usually, she'll be wrong and not pregnant, but occasionally, she'll be right and in such cases the BCP should be immediately stopped. Emergency Contraception Within 72 hours of unprotected intercourse, birth control pills can be taken in such a way as to reduce the likelihood of pregnancy occurring. Two Ovral (not Lo-Ovral) are taken, followed 12 hours later by two more Ovral pills. No additional pills are taken. Should Ovral not be available, good alternatives include: Lo-Ovral (four pills initially, followed by four more, 12 hours later) Nordette (four pills initially, followed by four more, 12 hours later) Levlen (four pills initially, followed by four more, 12 hours later) Triphasil (four pills initially, followed by four more, 12 hours later) Trilevelen (four pills initially, followed by four more, 12 hours later) If none of these pills are available, it is likely that any standard low-dose BCP (four pills initially, followed by four more, 12 hours later) will have similar effects. These other preparations have not been studied in as much depth, however, so it is certainly preferable to use one of the listed BCPs. With the use of emergency contraception, the risk of a pregnancy occurring is reduced by about 75%. If 100 women have a single episode of unprotected intercourse during the middle two weeks of their menstrual cycle, normally about 8 of them will conceive. If they all use emergency contraception, only about 2 of them will conceive, a 75% reduction in risk of pregnancy. The greatest experience with emergency contraception has been within the 72-hour window. Some studies find emergency contraception is most effective the sooner it is initiated within that 72 hours. Other studies find no difference in pregnancy rates. A few studies have looked at the use of emergency contraception for up to 120 hours after unprotected intercourse and find that it can still be effective in some cases, even after 72 hours. The menstrual cycle is usually unaffected by the use of emergency contraception. Breast tenderness is variable. Significant nausea occurs in about half of women and vomiting affects in about one in 6 women. These symptoms generally disappear within a day or two and can be moderated by using any standard anti-emetic or anti-nausea drug starting an hour before the BCPs are taken. If started after the onset of symptoms, these medications are not likely to be effective. The mechanisms by which this contraceptive effect occurs have not been established, but should a pregnancy occur despite the use of these BCPs, there is no evidence of harm to the fetus from having been exposed. Contraindications to use of emergency contraception are essentially the same as those for use of the birth control pill in general. Previous stroke, undiagnosed uterine bleeding, heart attack, deep vein thrombophlebitis and cancer of the breast or uterus are all contraindications to sustained pill use. The extent to which they represent risks in the context of emergency contraception is not known, but should be weighed in evaluating a patient for emergency contraceptive use. Overdose A single overdose of BCPs is not likely to cause any serious harm. Nausea, breast tenderness, and possibly a BCP withdrawal bleed (menstrual flow or spotting) are possibilities if large numbers of BCPs are taken all at once. Gastric lavage or induced vomiting are unnecessary. If the overdose was accidental, consideration of alternative methods of contraception can be explored, particularly those requiring less individual attention to detail. If the overdose was intentional, psychiatric evaluation is important as other, more threatening attempts at self-harm may follow. Other Contraceptive Methods Condoms A condom is a latex or animal skin sheath that fits over the penis. During orgasm, with ejaculation of semen, the sperm are trapped within the condom, preventing pregnancy. The condom is very effective, with annual failure rates of about 2%. Reasons for failure include non-use, breakage of the condom during intercourse, or loss of the condom. This loss most often occurs after ejaculation as the penis is returning to its' non-erect size. To prevent loss of the condom at this time, it is important to hold onto the base of it when the penis is withdrawn from the vagina. Making sure to roll the condom completely down (rather than partway down) over the erect penis will also help prevent its loss during intercourse. Use of high-quality, new condoms is also advisable. Tiny pinholes in the condoms are not likely to be a cause for failure and the process of checking for such tiny openings is likely to weaken the condom, increasing the chance for breakage. Some condoms are pre-lubricated. While this makes them somewhat more difficult to put on (they are slippery), the lubrication increases their heat and surface contour conduction, making their use seem less "artificial," and improving sensitivity. For couples in whom vaginal lubrication is insufficient, lubricated condoms can be helpful. Use of petroleum jelly as a lubricant is probably not a good idea as latex is soluble in petroleum products and the lubricant may weaken the condom. Some condoms are packaged with a spermicide (nonoxynol-9). This addition increases their effectiveness somewhat, but condoms are still considered about 98% effective. That is, 2 women out of 100 will become pregnant each year if condoms are used as contraception. Some couples place the condom on the male just prior to his orgasm, but after considerable penetrative sexual activity has already taken place. To maintain a high level of effectiveness, the penis should not come in contact with the vulva or vagina prior to placement of the condom. During sexual arousal but prior to orgasm, a small amount of clear liquid may appear at the tip of the penis. This liquid can contain both sperm and STDs. If the penis were to enter the vagina at this time, both pregnancy and infection are possible, even though male orgasm has not yet occurred. Some condoms have a reservoir tip to collect semen after ejaculation. Others have no such reservoir. For those condoms, it is a good idea to pinch the tip of the condom before applying it, creating an air-free space that can function as a reservoir tip. In addition to providing contraception, the condom also provides reasonably good protection against some sexually-transmitted diseases. The condom provides good protection against HIV, chlamydia, gonorrhea and syphilis...those STDs transmitted via semen or body fluids. The condom does not offer much protection against such STDs as condyloma (warts) or herpes, because these viruses are transmitted mainly through skin-to-skin contact and the condom does not totally cover all areas of intimate skin contact in the male, nor does it cover all of the vulnerable tissues in women. Condoms are also used to prevent STD transmission during oral sex. Condoms can be applied by either partner to the erect penis. It is nearly impossible to apply to a flaccid penis and would not likely remain in place, even if it were possible. Diaphragm A diaphragm is a latex-covered, flexible ring that fits inside the vagina, covering the cervix.  It prevents pregnancy by keeping sperm away from the cervix (the latex is impenetrable), and by holding spermicidal cream up against the cervix so that the few sperm who successfully find their way around the diaphragm are eliminated by the spermicide. It can be inserted up to several hours prior to intercourse, and should remain in place for at least 6 hours after intercourse. If multiple episodes of intercourse occur, additional contraceptive cream may be placed in the vagina, but diaphragm should not be dislodged. The diaphragm is very effective, with only about 5 failures per 100 women per year. Reasons for failure include non-use, improper positioning, or suboptimal use in addition to simple method failure. Diaphragms should be individually fitted. One commonly-used size is a 65 mm diaphragm (65 mm in diameter), but sizes range from 60 to 95 mm. A properly-fitted diaphragm will cover the cervix completely, will not move in the vagina, and will be so comfortable that the woman will not know that she is wearing it. Should a pelvic aching occur several hours after insertion, the diaphragm is too large and a smaller one should be substituted. If the woman complains that the diaphragm is uncomfortable or painful for her, the size would be rechecked and changed. Her partner should not be able to feel the diaphragm under ordinary circumstances. To remove the diaphragm, insert a finger into the vagina to hook the rim of the cervix. Pull it straight out and the flexible rim will fold as it comes out. After each use, the diaphragm should be washed with warm water and soap, rinsed well, and allowed to dry before returning it to its' case. Women with latex allergy cannot use the diaphragm as it will cause a reaction. There are non-latex diaphragms available, but they may prove difficult to obtain. Women who are sensitive to nonoxynol-9, the active ingredient in spermicidal creams, may or may not tolerate the diaphragm. A diaphragm is generally a good choice for women for whom a 5% failure rate each year is acceptable. It offers reasonably reliable contraception when needed without the potential side effects of hormonal contraception and infectious complications of IUDs. It has less of an "artificial" feel than condoms. A diaphragm is generally a poor choice for women who are relatively inexperienced sexually as it requires a moderate degree of manual dexterity, moderate familiarity with external and internal reproductive anatomy, and sexual circumstances that allow for either pre-positioning or a brief interruption in lovemaking in order to place the diaphragm correctly. DMPA Depot Medroxyprogesterone Acetate (DMPA, or DEPO-PROVERA*) was approved in late 1992 by the FDA for use as a long-acting, injectable contraceptive. Prior to 1992, many clinicians had used DMPA for this purpose without explicit FDA approval. 150 mg of DMPA are injected IM every three months, giving failure rates of slightly less than 1%. It is believed to exert its' contraceptive effect by some or all of the following: Inhibiting ovulation Changing cervical mucous Changing the lining of the uterus Altering fallopian tube function Other, as yet unclassified mechanisms The first injection is given within 5 days of the onset of menses. It is considered effective 7 days after it is given. DMPA should be given every 3 months, but there is a 2-4 week "grace period" at the end of the three months during which DMPA can be given and contraceptive efficacy remains unchanged. If the injection is more than 2-4 weeks late, then backup contraception should be used for the first month. It may be given post-partum. For women not breast-feeding, it should be administered within the first 5 days after delivery. For women who are exclusively breast-feeding, it should be administered during the 6th post-partum week. The following are considered reasons to avoid giving DMPA. Some might be considered absolute contraindications, while others are more relative. In general, you should avoid both. Undiagnosed vaginal bleeding Known or suspected pregnancy Known or suspected breast cancer Active thrombophlebitis History of embolism or cerebrovascular disease Active liver disease or dysfunction Known hypersensitivity to DEPO-PROVERA Measurable changes in bone mineral density occur, but this loss is not associated with an increased risk of pathologic fractures. The greatest loss is early in the use of DMPA and slows with longer use. The clinical significance of this finding is uncertain. Menstrual changes are the rule and not the exception among women using DMPA. Half of all women will develop amenorrhea by the end of one year's use. Spotting and intermenstrual bleeding are also common. Occasionally, this bleeding can be heavy. These abnormalities are often simply tolerated and considered an acceptable side-effect of this form of contraception. Alternatively, you may discontinue the injections and allow the drug to wear off. Finally, you may treat the abnormal bleeding with small doses of estrogen or oral contraceptive pills, but the impact on contraception of such treatment is unknown and patients should use backup contraception methods while BCPs or estrogen is being given. Ovulation resumes, on average 4.5 months after the last injection. Delay to conception after the last injection is approximately 10 months. In an uncontrolled study, 60% of women using DMPA gained weight during the first 6 months of use. The magnitude of the weight gain was 5 pounds at the end of 1 year, and 15-16 pounds at the end of three years. The problem with this study was the absence of a satisfactory control group. Many BCP studies have demonstrated the trend of women, as a group, to gain weight over time, whether they take BCPs or not. DMPA use probably does lead to some degree of additional weight gain, but the magnitude of this gain is uncertain. Headaches, breast tenderness, and psychological changes have all been described, but are uncommon. They may be temporary, so simply watching to see if they disappear is warranted unless the symptoms are severe. Among the psychological effects are diminished libido, fatigue, depression, and nervousness. There is no way of reversing the effects of DMPA other than letting it wear off, a process, which takes 4.5 months, on the average. If pregnancy occurs despite the use of DMPA, there is no good evidence that the DMPA will be harmful to the pregnancy. Because of theoretical concerns, DMPA should not be taken if pregnancy is known or suspected. *DEPO-PROVERA is the registered trademark of Pharmacia & Upjohn Company, Bridgewater NJ Female Condom Female condoms can be very effective in preventing pregnancy and providing reasonable protection against some sexually transmitted diseases. Each female condom is individually packaged and pre-lubricated. It is made out of plastic, not latex, so it is particularly useful for women and men with latex allergies. Each package contains an extra small tube of lubricant.  After removal of the condom from its' package, the inner ring is compressed into an oval shape. The inner ring is then inserted deeply into the vagina, so that it encircles the cervix. With proper positioning, the exterior ring will cover the vulva and remain outside the vagina. During intercourse, the penis is inserted through the outer ring into the vagina. It is a good idea to hold the outer ring in place while the penis is initially inserted. After intercourse, the outside ring is twisted to seal the semen inside the condom. Then the condom can be gently pulled straight out. It should be discarded in a trash container and not flushed, as it may clog the toilet. Although pre-lubricated, women may find they need additional lubrication. Some women can feel the condom inside the vagina and others cannot. Extra lubrication can be helpful if this sensation is a distraction. Some women find that intercourse while using the female condom produces distracting sounds. In this case, the use of additional lubricant can be helpful in silencing the noise. Additional spermicide (cream, foam or jelly) can be used safely with the female condom, although the degree to which this provides additional contraceptive effect is unknown. If extra spermicide is to be used, it is most likely to be helpful if placed in the vagina prior to insertion of the female condom. The effectiveness of the female condom in preventing pregnancy is roughly the same as the use of a diaphragm. When used carefully and consistently with each episode of intercourse, there will be about 5 failures per 100 women per year (95% effective). When all women who use this method are evaluated, including those, whose use is not always careful and not necessarily consistent, the annual failure rate (pregnancy rate) is about 20%. Contraceptive Vaginal Film Contraceptive vaginal film is available for use as either a primary method of contraception or to increase the effectiveness of other methods, such as condoms. Each film is a semi-transparent square of a dissolvable material containing nonoxynol-9, a standard spermicide. After opening the individual film wrapper, the film is removed and folded once in half. Use dry fingers; otherwise the film will begin to melt and will become unmanageable. The film is then folded in half once again and folded over the index or middle finger. Push the folded film deep into the vagina so that it is up against the cervix. After insertion, the film needs 15 minutes to melt to form an effective spermicidal barrier. Once in place, it is effective for up to one hour after insertion. If additional intercourse is performed, an additional film should be inserted. The film dissolves completely and does not need to be removed. It will be discharged over time with the normal vaginal secretions and body fluids. If douching is desired, it should not be done during the first 6 hours after intercourse as some of the contraceptive protection may be lost. Because the active ingredient is nonoxynol-9, some individuals (up to 20% of the population) will be sensitive to it and experience a burning sensation during use. Those individuals should not continue to use this method of contraception and should seek another alternative. Effectiveness of the film is probably similar to that of the diaphragm. If used carefully and consistently, about 5 women out of 100 will become pregnant each year, despite the use of contraceptive vaginal film. For the average user, failure rates are likely higher, about 15 or 20% each year. Contraceptive Foam Contraceptive foam is a good contraceptive choice for many women. Foam comes in a pressurized container with a plastic applicator. After placing the aerosol container in an upright position on a solid surface, the applicator is positioned over the top of the can and gentle downward pressure exerted. This pressure will release foam into the applicator, gradually filling it. The applicator should be filled to the ribbed section (about 80% full). The applicator is then inserted into the vagina and the plunger depressed with the index finger, pushing the foam into the vagina. It is immediately effective, and remains effective for up to one hour after insertion. If intercourse is repeated, a second applicator of foam should be used.. The foam will gradually leak out of the vagina over the next several hours. If douching is desired, it should not be done during the first 6 hours after intercourse, because some of the contraceptive effectiveness of the foam may be lost. After each use, the applicator should be washed with warm water and a mild soap. The applicator may be disassembled for cleaning. The active ingredient in the foam is the standard spermicide, nonoxynol-9. This is also the material that may produce a local burning sensation in up to 20% of those using it. If the woman or her partner has this sensitivity, he or she will be sensitive to any of the nonoxynol-9 products (gel, cream, etc.). Effectiveness is similar to that of the diaphragm. If used carefully and consistently, about 5 women out of 100 will become pregnant each year, despite the use of contraceptive foam. For the average user, failure rates are higher, about 15 or 20% each year. Contraceptive Vaginal Gel Contraceptive vaginal gel is used either alone or in combination with other contraceptive techniques such as condoms. Each gel applicator is individually wrapped and contains nonoxynol-9, a standard spermicide. After opening the package, the cap is removed and used as a plunger for the applicator. The applicator is pushed into the vagina and the plunger depressed to deposit the gel inside the vagina. After insertion, the gel is effective immediately. Once in place, it is effective for up to one hour after insertion. If additional intercourse is performed, additional gel should be inserted. The gel forms a spermicidal barrier within the vagina. It does not need to be removed as it will gradually discharge over the next few hours. Douching, if desired, should not occur during the first 6 hours after use, because some of the contraceptive protection may be lost. Because the active ingredient is nonoxynol-9, some individuals (up to 20% of the population) will be sensitive to it and experience a burning sensation during use. Those individuals should not continue to use this method of contraception and should seek another alternative. Effectiveness of the vaginal gel is similar to that of the diaphragm. If used carefully and consistently, about 5 women out of 100 will become pregnant each year, despite the use of contraceptive vaginal gel. For the average user, failure rates are likely higher, about 15 or 20% each year. Intrauterine Device (IUD) IUDs have been known and used for thousands of years in large domestic animals, but only recently have humans used them. Modern IUDs are easily inserted, have a very high effectiveness rate (98-99%), and are well-tolerated by most of the women who use them. Their effectiveness continues for varying lengths of time, depending on the type of IUD. The "Copper T 380A," used frequently in the United States, can remain in place for 10 years before removal is recommended. IUDs tend to make menstrual flows somewhat heavier, crampier and longer, a consideration in assessing the appropriateness of an IUD for any individual patient. While many IUDs were known to be safe and effective, one in particular, the Dalkon Shield, seemed to have more than its' share of problems, the most important of which was infection. Pelvic infections, infrequent and usually minor with the other IUDs, tended to be more frequent and more severe among Dalkon Shield users. Many of these infections were so serious as to render the patient permanently sterile or to necessitate a hysterectomy. There were two reasons for these infections; a design flaw and a marketing flaw. The design flaw was located in the "tail" or string used to remove the IUD. After insertion, the string is left protruding through the cervix so it is visible on pelvic exam. This confirms that the IUD is correctly placed and facilitates removal at a later date. The Dalkon Shield string was made up of many tiny plastic filaments and encased in a plastic sheath. This design inadvertently caused the string to act as a wick, constantly drawing vaginal bacteria up through the cervix and into the uterine cavity where they could cause infection. The other IUDs had monofilament strings that did not have the same wicking capacity. The design, in retrospect, predisposed the Dalkon Shield to infections. The marketing flaw was to promote IUD among young, single women without children. These women tended to have greater risk of exposure to sexually transmitted disease and multiple sexual partners. They tended to be more likely to seek medical attention late in the course of the illness. The consequences of permanent infertility among these young women was devastating. While the design and marketing flaws of the Dalkon Shield are of primarily historical interest, the lessons learned at a terrible cost should not be forgotten in looking at more modern IUDs. With the newer designs, the risk of infection has been significantly reduced. Sooner or later, about 3-5% of IUDs will be removed because of infection. Most of these infections are minor, with mild symptoms of vague pelvic discomfort, painful intercourse and possibly a low-grade fever. The uterus is tender to palpation although the adnexa usually are not. Treatment of such mild infections generally involves prompt removal of the IUD, oral broad spectrum antibiotics and complete resolution of symptoms. Infertility following such mild infections is uncommon. With the less common, serious infections, a high fever can be found, movement of the cervix causes excruciating discomfort and the adnexa are extremely tender. In addition to prompt removal of the IUD, IV antibiotics are recommended to treat this moderate to severe PID. In these cases, recovery is generally slow (days to weeks) and infertility is a distinct possibility. The overall risk of perforation of the IUD through the uterine wall is about 1 in 1,000. Most of these occur during the insertion of the IUD or shortly thereafter. More common than perforation is the "disappearance" of the IUD string. While such a disappearance may suggest the possibility of perforation, a more likely explanation is that the string has coiled up inside the cervical canal or even inside the uterus. A truly perforated IUD is usually removed from the abdominal cavity with laparoscopic or open surgery. When confronted with a missing IUD string, most clinicians will gently probe the cervical canal to see if they can tease the string back down through the os. A cotton-tipped applicator or a Pap smear brush works well for this purpose. Once the string is brought down into the vagina (and about 3/4 will be found this way), nothing further needs to be done. If the string is not inside the cervical canal, then further evaluation and treatment will be needed from an experienced and well-equipped gynecologic consultant. X-ray can confirm that the IUD remains somewhere within the pelvis. Ultrasound can demonstrate the presence of the IUD inside the uterine cavity. For an IUD which is clearly inside the uterine cavity but whose string has retracted into the cavity, a careful judgment must be made. In some circumstances, the IUD is removed with an IUD hook, D&C or hysteroscopy, and a new once replaced. In other circumstances, it may be appropriate to leave the IUD where it is until the 10 years have expired before removing it. IUDs are very effective at preventing pregnancy, but there is a small failure rate of about 1-2% each year. If pregnancy occurs, it is important to remove the IUD immediately (that day). The normal spontaneous miscarriage rate is about 18-20%. For women who conceive despite an IUD, the miscarriage rate is about 25% when the IUD is removed immediately. If the IUD is left in place, the miscarriage rate increases to about 50%, and many of those are septic mid-trimester losses which are particularly unpleasant and which are associated with subsequent infertility in some cases. If deployed, even the relatively inexperienced health care provider can remove the IUD because: 1) it is simple and easy to do, and 2) delaying removal for several days until a more experienced provider can see the patient risks retraction of the string up inside the uterus, making simple removal impossible. The IUD should first be removed and then the patient moved to a definitive care setting in anticipation of a possible miscarriage. Should a pregnancy occur despite the presence of an IUD, there is an increased likelihood that it will be an ectopic pregnancy. Instead of the typical rate of about 1%, the ectopic pregnancy rate is about 5%. This means that in addition to prompt removal of the IUD, the patient needs a careful evaluation with ultrasound and possibly adjunctive laboratory tests to determine the presence of the pregnancy. Should an ectopic pregnancy be found, medical and/or surgical management is usually undertaken. In many military settings, such an evaluation may not be possible and medical evacuation should be considered. A good candidate for an IUD is: an older woman with children, who is in a stable, mutually monogamous sexual relationship, and who is not planning additional pregnancies. A bad candidate for an IUD is: a young woman with no children, with multiple sexual partners, with a history of PID in the past, who would like to have children at some time in the future. Most women considering an IUD don't fit perfectly into either category, so some judgment must be used. Contraindications to IUD use include: Known or suspected pregnancy Known distortion of the uterine cavity PID past or current Pregnancy-related infection within the last 3 months Known or suspected cervical cancer Undiagnosed vaginal bleeding Current cervicitis or vaginitis until effectively treated Wilson's disease Allergy to copper Impaired immune system Genital actinomycosis An IUD can be inserted at any time, provided the physician is confident that the patient is not currently pregnant. Many physicians prefer to insert the IUD during a normal menstrual flow. This provides some assurance that the patient is not currently pregnant. Second, the cervical canal is already somewhat dilated from the menstrual flow and so the actual IUD insertion is more comfortable for the patient. Third, there is usually a small amount of bleeding following insertion of the IUD which will not be noticed if the patient is currently flowing. The IUD may be inserted at the 6-week postpartum check. Insertion usually causes mild uterine cramping which disappears in a few minutes. Pretreatment with a NSAID can block much of that discomfort. The use of prophylactic antibiotics is an unresolved controversy. An IUD can be removed at any time, but should be removed in the presence of pelvic infection, pregnancy, and abdominal pain of uncertain cause or if the IUD is already partially extruded. Never push a partially extruded IUD back inside the uterus as you will introduce significant bacterial contamination into either the uterus or the abdominal cavity, whichever area you penetrate. After placing a vaginal speculum, visualize the cervix and the IUD string(s) protruding through the cervical os. Grasp the strings with any convenient instrument (hemostat, dressing forceps, ring forceps, etc.) and pull the IUD straight out with a steady, smooth, slow pull. The IUD, by virtue of its' pliability, will fold onto itself and slide out. Most patients will feel either no discomfort or minimal uterine cramping during removal. They generally comment that having the IUD removed was not as uncomfortable as having it inserted. Norplant Norplant (Norplant is the registered trademark of the Wyeth-Ayerst Laboratories, Philadelphia, Pennsylvania) consists of six soft, flexible Silastic tubes, each containing levonorgestrel (LNG, the same progestational agent found in LoOvral), and implanted just below the skin of the inner, upper arm. The tubes are 34 mm long and 2.4 mm in diameter, and initially release about 85 mcg of LNG each day. In time, the daily release of LNG falls, ultimately stabilizing at about 30 mcg per day. If left in place, the tubes continue to effectively prevent pregnancy for at least 5 years. It is believed to exert its' contraceptive effect by some or all of the following: Inhibiting ovulation Changing cervical mucous Changing the lining of the uterus Altering fallopian tube function Other, as yet unclassified mechanisms When removed, fertility returns promptly. During the first year of use, the failure rate is 0.2%, comparable to the failure rate of BCPs. During the next 5 years, the failure rate rises slowly to about 1% by the 5th year. Contraindications include: Undiagnosed vaginal bleeding Known or suspected pregnancy Known or suspected breast cancer Active thrombophlebitis or thromboembolism History of idiopathic intracranial hypertension Benign or malignant liver tumors or other acute liver disease Known hypersensitivity to LNG or Silastic About half of all women using Norplant will experience abnormal bleeding patterns, consisting of spotting, prolonged bleeding, unpredictable onset of flow and amenorrhea, primarily in the first year of use. While overall, the number of days of some bleeding in these women usually increases, the total amount of blood loss usually decreases, and anemia is not a problem. This side effect, abnormal bleeding, is generally tolerated and no treatment is necessary. For the woman who is quite distressed, or in whom the bleeding is clinically significant, control with BCPs is usually effective, but may alter the effectiveness of the method and theoretically could lead to an increased risk of thrombophlebitis or other hormone-related side effect. Removal of the implants may occasionally be necessary. Weight gain, weight loss, nausea and depression have all been reported in association with this drug, but it is unknown whether they occur more frequently among women using the implants or not using the implants. If the symptoms are mild, toleration will usually bring relief in time. If symptoms are severe, removal of the implants may be necessary. Infection at the implant site is an uncommon complication (0.7%), but is treated by removal of the implants, bacterial cultures and antibiotics. The implants are inserted in the inner, upper arm (non-dominant side), and 8-10 cm above the elbow crease, in a fan-like pattern, just beneath the dermis. When in place, they are typically invisible, but may be seen in extremely thin patients. In women with darker skin tones, a hyperpigmentation (even darker area) may develop over the implants, outlining their position, but this coloration is temporary and resolves after removal of the implants. They can be felt, but will not move or migrate away from the insertion site. After giving a small amount of local anesthetic, 2 mm incision in the skin is made and a trocar introduced. Through the trocar, the Silastic tubes are inserted in a fan-like fashion. The incision to closed with a steri-strip. For removal, local anesthetic is injected to allow a 3-5 mm skin incision at the base of the "fan." 3 ml of anesthetic in injected beneath the implants. Push one implant toward the incision with your fingers and grasp it with a hemostat. Before it can be removed, you will need to open the fibrous capsule, which will have developed around the implant. Open the capsule with a scalpel or another hemostat. Then grasp the implant and pull it straight out through the incision. Continue in the same way with the other implants until all 6 are removed. Sometimes, there will have been some migration of the implants, making removal of all of them difficult. Under these circumstances, if reasonable efforts to retrieve all of them are not successful, it may be better to stop, wait 4-6 weeks for healing and resolution of any inflammation, and then try again. New implants may be inserted at the time of the removal of the old ones, either in the same or in the opposite direction. Rhythm The rhythm method of contraception involves avoiding unprotected intercourse during the fertile time. Ovulation occurs approximately 14 days prior to the onset of the menstrual flow. For women with regular, predictable menstrual periods, this means that by avoiding unprotected intercourse around the time of ovulation, pregnancy can be prevented. Fertilization must occur within 24 hours of ovulation to be successful. Sperm can appear at the end of the fallopian tube within 10 minutes of male orgasm and can remain there for at least 48 hours, sometimes longer. For a woman with regular, predictable periods occurring every 28 days, avoiding unprotected intercourse from approximately day #9 through day #19 (5 days on either side of the expected ovulation) will provide reasonable protection against pregnancy (70-80%). Failures occur because of: Earlier than expected or later than expected ovulation. Sperm living longer than expected in the fallopian tube. For women with longer menstrual cycle frequencies (32 days, for example), the days to avoid unprotected intercourse should be adjusted. For a 32-day cycle, ovulation usually occurs 14 days prior to menses, on day #18. This means avoiding unprotected intercourse from day #13 through day #23. If fewer than 5 "off days" on either side of ovulation are used, this method will be less effective. If more than 5 "off days" are used, this method becomes more acceptable. It can never be 100% effective, however, since pregnancies have been recorded following intercourse on any day of the menstrual cycle. If an annual failure rate of 20-30% is not acceptable, or if menstrual periods are irregular, other forms of contraception may prove more satisfactory. Vaginal Suppositories Each suppository is individually wrapped and contains nonoxynol-9, a standard spermicide.  After opening the package, the suppository is pushed deeply into the vagina so that it lies against the cervix. After insertion, the suppository needs 10 minutes to melt to form an effective spermicidal barrier. Once in place, it is effective for up to one hour after insertion. If additional intercourse is performed, an additional suppository should be inserted. The suppository forms a spermicidal foam barrier within the vagina. It does not need to be removed as the foam will gradually discharge over the next few hours. Douching, if desired, should not occur during the first 6 hours after use, because some of the contraceptive protection may be lost. Because the active ingredient is nonoxynol-9, some individuals (up to 20% of the population) will be sensitive to it and experience a burning sensation during use. Those individuals should not continue to use this method of contraception and should seek another alternative. Effectiveness of the vaginal suppository is similar to that of the diaphragm. If used carefully and consistently, about 5 women out of 100 will become pregnant each year, despite the use of contraceptive vaginal suppository. For the average user, failure rates are likely higher, about 15 or 20% each year. Tubal Ligation Tubal ligation is a highly effective method of permanent sterilization. It is a surgical procedure that can be performed in a number of different ways, including outpatient laparoscopic surgery, post partum surgery, or during a cesarean section. It is approximately 99% effective (failure rate of about 1%). It should be considered permanent and irreversible, although in some cases, following major surgery, it can be successfully reversed. It is not a good choice for anyone who may wish to have children in the future. The advantages are permanent sterilization, with no need for hormones, mechanical or chemical methods to prevent further pregnancy. The disadvantages relate primarily to the surgical procedure itself: infection, bleeding, injury to other organs, and anesthesia complications. These are uncommon with this type of surgery. Vasectomy Vasectomy is a highly effective method of permanent male sterilization. This surgical procedure is usually performed as an outpatient, using local anesthetic, and lasting a few minutes. The vas deferens (tube connecting the testicle to the urethra) on each side is tied off. After a number of later ejaculations, during which the remaining downstream sperm disappear from the system, permanent sterilization is achieved. It is approximately 99% effective (failure rate of about 1%). It should be considered permanent and irreversible, although in some cases, it can be reversed. The greatest success rates at reversal are achieved if reversal occurs soon after the vasectomy. The longer reversal is delayed, the less effective it is likely to be. For men who may wish to have children in the future, vasectomy is not a good choice. The advantages are permanent sterilization, with no need for hormones, mechanical or chemical methods to prevent further pregnancy. The disadvantages relate primarily to the surgical procedure itself: infection, bleeding, injury to other organs, and anesthesia complications. These are uncommon with this type of surgery. Withdrawal Around the world, withdrawal is the most commonly used form of contraception. Also known as "coitus interruptus," or "pulling out," the penis is withdrawn from the vagina just before ejaculation. Orgasm is usually completed by manual stimulation. Withdrawal has some significant advantages: It is reasonably effective (80-90%). It involves no mechanical devices, medications, or chemicals It is always available and requires no preparation Withdrawal as a contraceptive method has some problems: Its effectiveness is very dependent upon the male sense of timing. Some men are more skilled at this than others. It requires mental resolve on the part of the male at the precise moment when the power of passion and instinct is formidable. Because of the pre-orgasmic secretion of male prostatic fluid, some sperm may be deposited in the vagina even before ejaculation has occurred. During the few minutes after ejaculation, the initially thick, globular semen liquefies. In this more liquid form, it is relatively easy for some of the semen to come into contact with the vulva, particularly if there is continuing intimate contact. Pregnancies have occurred under these circumstances, even without vaginal penetration, although they are not common. Some men find withdrawal to be psychologically and physically less satisfying for a variety of reasons. The sensations are not identical to orgasm at full penetration, and the sense of completion is different. Some women find withdrawal to be psychologically and physically less satisfying for similar reasons. Bleeding Normal Bleeding Normal menstrual bleeding: Occurs approximately once a month (every 26 to 35 days). Lasts a limited period of time (3 to 7 days). May be heavy for part of the period, but usually does not involve passage of clots. Often is preceded by menstrual cramps, bloating and breast tenderness, although not all women experience these premenstrual symptoms. Abnormal Bleeding Abnormal bleeding (DUB or dysfunctional uterine bleeding) includes: Too frequent periods (more often than every 26 days). Heavy periods (with passage of large, egg-sized clots). Any bleeding at the wrong time, including spotting or pink-tinged vaginal discharge Any bleeding lasting longer than 7 days. Extremely light periods or no periods at all Overview Any woman complaining of abnormal vaginal bleeding should of course be examined. Occasionally, you will find a laceration of the vagina, a bleeding lesion, or bleeding from the surface of the cervix due to cervicitis. Much more commonly, you will find bleeding from the uterus coming out of the cervical os. Excluding pregnancy, there are really only three reasons for abnormal uterine bleeding: Mechanical Problems Hormonal Problems Malignancy The limited number of possibilities makes your caring for these patients very simple. First, before examining the patient, obtain a pregnancy test. If it is positive, then don't do anything more until you've read about the different possible causes. Next, obtain a blood count and assess the rate of blood loss to determine how much margin of safety you have. Someone with a good blood count (hematocrit) and minimal rate of blood loss (less than a heavy period), can tolerate this rate of loss for many days to weeks before the bleeding itself becomes a threat. Pregnancy Problems A variety of pregnancy problems can cause vaginal bleeding. These include: Abortion (threatened, incomplete, complete, missed, or inevitable) Ectopic Pregnancy Placental Abruption Placenta Previa If the bleeding patient has a positive pregnancy test, a careful search should be made for each of these problems. However, if the pregnancy test is negative, pregnancy-related bleeding problems are effectively ruled out. Mechanical Problems Such problems as uterine fibroids or polyps are examples of mechanical problems inside the uterus.  Since mechanical problems have mechanical solutions, these patients will need surgery of some sort (Polypectomy, D&C, Hysteroscopy, Hysterectomy, Myomectomy, etc.) to resolve their problem. In the meantime, have them lie still and the bleeding will improve or temporarily go away. Giving hormones (like birth control pills) in an effort to stop the bleeding will not help this condition, but neither will it be harmful. Polyps visible protruding from the cervix are usually coming from the cervix and can be easily twisted off. However, they will need microscopic evaluation, so removal in many operational settings may not be desired. Instead, they can await return to a non-deployed setting. Another form of mechanical problem is an IUD causing abnormal bleeding. These should always be removed. Hormonal Problems Hormonal causes for abnormal bleeding include anovulation leading to an unstable uterine lining, breakthrough bleeding associated with birth control pills, and spotting at midcycle associated with ovulation. The solution to all of these problems is to take control of the patient hormonally and insist (through the use of BCPs) that she have normal, regular periods. If the bleeding is light and her blood count good, simply start BCPs (low-dose, monophasic, such as LoOvral or Ortho Novum 1+35 or Ovcon 35, etc.) at the next convenient time. After a month or two, her bleeding should be well under control. If the bleeding is quite heavy or her blood count not so good, then it is best to have her lie still while you treat with birth control pills. Some gynecologists have used 4 BCPs per day initially to stop the bleeding, and then taper down after several days to three a day, then two a day and then one a day. If you abruptly drop the dosage, you may provoke a menstrual flow, the very thing you didn't want. Giving iron supplements is a good idea (FeSO4 325 mg TID PO or its' equivalent) for anyone who is bleeding heavily. Malignancy Abnormal bleeding can also be a symptom of malignancy, from the vagina, cervix or uterus. Cancer of the vagina is extraordinarily rare and will present with a palpable, visible, bleeding lesion on the vaginal wall. Cancer of the cervix is more common but a normal Pap smear and normal exam will effectively rule that out. Should you find a bleeding lesion in either the vagina or on the cervix, these should be biopsied. Cancer of the uterus (endometrial carcinoma) occurs most often in the older population (post-menopausal) and is virtually unknown in patients under age 35. For those women with abnormal bleeding over age 40, an endometrial biopsy is a wise precaution during the evaluation and treatment of abnormal bleeding. What to do First Since most (90%) of the non-pregnancy bleeding is due to hormonal causes, and since in operational settings you probably don't have quick access to a D&C, your best bet is to: Get a pregnancy test Get a blood count Examine the patient Put the patient to bed if the bleeding is heavy Begin BCPs If this doesn't work, you'll need to MEDEVAC the patient to a definitive care facility, since surgery is the next step for women who do not respond to hormonal control. Obviously, women who are pregnant should not receive BCPs, and pregnant women of more than 20 weeks gestation should be examined vaginally only in a setting in which you are prepared to do an immediate cesarean section should you discover an unsuspected placenta previa. Heavy Periods Heavy periods ("menorrhagia," "hypermenorrhea") and lengthy periods may reflect an underlying mechanical abnormality inside the uterus (fibroids, polyps), may be a cause of iron-deficiency anemia, may contribute to uncomfortable menstrual cramps, and may be a significant inconvenience in an operational setting. If the examination, Pap smear, and pregnancy test are normal, then the chance of malignancy is very low and need not be further considered unless symptoms persist. One good approach is to give birth control pills to women with these heavy periods. The effect of the BCPs is to reduce the heaviness and duration of flow. If they are anemic, oral iron preparations will usually return their iron stores to normal. If the BCPs (standard, low dose, monophasic pill such as Ortho Novum 1+35, LoOvral or LoEstrin 1.5/30) fail to reduce the flow appreciably, they can be taken continuously, without the usual "week off." This will postpone their menstrual period for as long as several months. Even though their period may still be heavy or lengthy, the fact that they only have it every few months rather than every 4 weeks will have a major impact on their quality of life and anemia, if present. On return to non-operational status, a gynecologic consultation is usually advisable. Alternatively, you could start the patient on DMPA (depot medroxyprogesterone acetate) 150 mg IM Q 3 months. This will usually disrupt the normal period and she probably won't continue to have heavy periods. There are some significant drawbacks to this approach, however. Light spotting or bleeding are common among women taking DMPA, so you will be substituting one nuisance for another nuisance. Light Periods Extremely light periods, so long as they occur at the right time, are not dangerous and really are not a medical problem. This condition is most often seen among women taking low dose birth control pills. The birth control pills usually act by blocking the normal ovarian function (production of various hormones and ovulation), and then substituting the hormones (estrogen and progestin) found in the BCPs. Usually, the result of this exchange is that the circulating estrogen levels are about the same as if the woman were not taking BCPs. In some women, however, the estrogen levels are significantly lower than before they started taking the BCPs. In this case, they will notice their menstrual periods getting lighter and lighter (over 3 to 6 months), and possibly even disappearing altogether. This is not dangerous, has no impact on future fertility, and will resolve spontaneously if the BCPs are stopped. Stopping the BCPs is not necessary, however, because there are other safe alternatives. If the periods are simply very light (1-2 days), you can ignore the problem because this situation poses no threat to the patient. If periods have totally stopped: Rule out pregnancy. You may change to a different BCP with different hormone in it. This will often lead to recognizable periods because the different hormone is metabolized differently. You may add estrogen (Premarin .625 mg or Esterase 1 mg) to each BCP to increase the estrogen stimulation of the uterine lining, increasing its' thickness and leading to heavier periods. After the desired effect has been achieved (recognizable periods), the extra estrogen can be stopped. You may safely reassure the patient and allow her to not have periods while taking the BCPs. As long as she otherwise feels well, the absence of periods while taking BCPs is not known to have any adverse effects and some women prefer to avoid monthly flows. Late for a Period Pregnancy should be ruled out with a pregnancy test. If the pregnancy test is negative and the patient is not taking hormonal contraception, then simple observation for a single missed period is the usually the wisest course. Delay of periods in operational settings is common. In Boot Camp, among women not on BCPs, about 1/3 of women will skip periods for up to three months. The same observation is found among college freshman women. Presumably, this is a stress response. If the patient remains without a period for an extended length of time (3 months or more), then the following are often done: Normal menstrual flows are re-established with either BCPs, or Provera (10 mg a day x 5 days, followed 3 days later by a period). Provera works well if ovarian function is not deeply depressed, but will not work for some women. BCPs will usually work regardless of the degree of ovarian suppression. The patient is tested for thyroid malfunction. (TSH or Thyroid Stimulating Hormone test). The patient is tested for prolactin disorders. (prolactinoma, often associated with inappropriate milk secretion from the nipples) The patient is tested for premature ovarian failure. (FSH/follicle stimulating hormone and LH/luteinizing hormone) If any of these tests are abnormal or neither Provera nor BCPs are effective in restarting normal periods, gynecologic consultation upon return to garrison is indicated. Irregular Periods This means menstrual periods coming at unpredictable intervals, rather than the normal once-a-month cycles. If the flows, whenever they come, are normal in character and length, this is not a dangerous condition and no treatment or evaluation is required. If the patient finds the irregular character of her periods to be troublesome, then starting low dose BCPs will be very effective in giving her quite normal, once-a-month menstrual flows. If the flows, whenever they come, are not consistent; are sometimes heavy, are sometimes light, are sometimes only spotting, then they are likely not true menstrual cycles, but are anovulatory bleeding (uterine bleeding occurring in the absence of ovulation). This condition should be treated with re-establishment of normal, regular periods, usually with BCPs. Unresolved anovulatory bleeding may, over many months to years, lead to cosmetic problems (unwanted hair growth due to relative excess of male hormones) and uterine lining problems (endometrial hyperplasia due to a lack of the protective hormone progesterone). Too Frequent Periods Periods that are too frequent (more often than every 26 days, "metrorrhagia") can be related to several predisposing factors: If the periods are otherwise normal, then a short "luteal phase" or insufficient ovarian production of progesterone may be responsible. If the periods are inconsistent, then failure to ovulate and the resulting anovulatory bleeding may be responsible. If the periods are actually normal and once a month, but there are episodes of bleeding in between the periods, then mechanical factors such as fibroids or polyps may be responsible. In operational settings, a very good treatment for all of these underlying factors is starting BCPs. On return to garrison, gynecologic consultation is usually indicated to assess the adequacy of symptom suppression and to evaluate the patient for any predisposing, treatable factors. Constant Bleeding Women who experience significant daily bleeding for a very long time (weeks) sometimes develop another kind of problem unique to this circumstance, denuding of the uterine lining. Normally, small breaks or tears in the uterine lining are promptly repaired. For women who have been bleeding for weeks, with the accompanying uterine cramping, the uterine lining becomes very nearly completely lost. There is so little endometrium left that the woman will have difficulty achieving repair and restoration of the normal lining without external assistance. A common example of this situation would be a teenager who has been bleeding for many weeks but who, through embarrassment, has not sought medical attention. On arrival, she continues to bleed small amounts of bright red blood. She is profoundly anemic, with hemoglobin of 7.0. These patients do not respond to simple BCP treatment because the BCPs are so weak in estrogen and so strong in progestin that the uterine lining barely has a chance to grow and cover up the denuded, bleeding areas inside the uterus. These patients need strong doses of plain estrogen, to effectively stimulate the remaining uterine lining (causing it to proliferate). Premarin, 2.5 to 5 mg PO per day, or IV (25 mg slowly over a few hours) will provide this strong stimulus to the uterine lining and if combined with bedrest, will usually slow or stop the bleeding significantly within 24 hours. The estrogen is stimulating the uterine lining to grow lush and thick. The estrogen is continued for several days, but at lower dosages (1.25 to 2.5 mg per day) until the bleeding completely stops. Then, progesterone is added (Provera 5-10 mg PO per day) for 5-10 days. Progesterone is necessary at this point because the lush, thick uterine lining is also very fragile and easily broken. Progesterone provides a structural strength to the uterine lining, making it less likely to tear or break. Once a normal, thick, well-supported lining has been re-established, first with estrogen, then with the addition of progesterone, it will need to be shed, just like a normal lining is shed once a month. Stopping all medication will trigger a normal menstrual flow about 3 days later. The lining will have been restored and the vicious cycle of bleeding leading to more endometrial loss leading to more bleeding will be broken. Future periods may then be normal, although many physicians will start BCPs at that point to prevent recurrence of the constant bleeding episode. Hemorrhage Hemorrhage is defined differently by different texts, but three good general guidelines are these: If the bleeding is heavier than the heaviest menstrual period the patient has ever experienced...that is hemorrhage. If, when standing, blood is running down her leg and dripping into her shoes...that is hemorrhage. If, because of heavy vaginal bleeding, the patient cannot stand upright without feeling light-headed or dizzy...that is hemorrhage. Vaginal hemorrhage is more often associated with pregnancy complications such as miscarriage or placental abruption, but certainly can occur in the absence of pregnancy. This is a true medical emergency and a number of precautionary steps should be taken: IV access should be established to facilitate fluid resuscitation Blood transfusion should be made readily available, if it proves necessary. Pregnancy must be excluded as its presence may profoundly effect the treatment. Bedrest will lead most cases of hemorrhage to slow, regardless of the cause. Medical evacuation should be planned as the definitive treatment of uterine hemorrhage not responsive to conservative measures is surgical. Helpful tips: Blood counts (hgb or hct) performed during an acute hemorrhage may be falsely reassuring as the hemoconcentration accompanying hemorrhage may take several hours to re-equilibrate in response to your IV fluids. Elevation of the legs to about 45 degrees will add as much as one unit of fresh, whole blood to the patient's circulation by eliminating pooling in the lower extremities. In severe cases of hemorrhage when surgical intervention is not immediately available, vaginal packing can slow and sometimes stop bleeding due to vaginal lacerations or uterine bleeding from many causes. After a Foley catheter is inserted in the bladder, a vaginal speculum holds the vaginal walls apart. Tail sponges, long rolls of gauze, 4 X 4's or any other sterile, gauzelike substance can be packed into the vagina. The upper vagina is packed first, with moderate pressure being exerted to insure a tight fit. Then, progressively more packing material is stuffed into the lower vagina, distending the walls. Ultimately, the equivalent of a 12-inch or 16-inch softball sized mass of gauze will be packed into the vagina. This has several effects: Any bleeding from the cervix or vagina will have direct compression applied, slowing or stopping the bleeding. The uterus is elevated out of the pelvis by the presence of the vaginal pack, placing the uterine vessels on stretch, slowing blood flow to the uterus and thus slowing or stopping any intrauterine bleeding. By disallowing the egress of blood from the uterus, intrauterine pressure rises to some extent, exerting a tamponade effect on any continuing bleeding within the uterus. Vaginal packing can be left for 1-3 days, and then carefully removed after the bleeding has stopped or stabilized. Sometimes, only half the packing is removed, followed by the other half the following day. The Foley catheter is very important, both to monitor kidney function and to allow the patient to urinate (usually impossible without a Foley with the vaginal packing in place). Vaginal Discharge and Itching Overview In operational settings, most women complaining of vaginal discharge will have no other associated symptoms (pain, bleeding, fever, vulvar lesions, etc.) You can solve 95% of these vaginal discharge complaints by asking two questions: Does it itch? Does it have a bad odor? If it itches, give the patient Monistat (or other antifungal medication). If there is a bad odor, give Flagyl. If it itches and has a bad odor, give both Monistat and Flagyl. You will solve most of the vaginal discharge problems and will miss nothing important for very long. Those women whose symptoms persist despite this expedient treatment will need a more thorough evaluation. For those, the diagnosis of vaginal discharge is based on a History, Physical Exam, and a few simple diagnostic tests. History Ask the patient about itching, odor, color of discharge, painful intercourse, or spotting after intercourse. Yeast causes intense itching with a cheesy, dry discharge. Gardnerella causes a foul-smelling, thin white discharge. Trichomonas gives irritation and frothy white discharge. Foreign body (lost tampon) causes a foul-smelling black discharge. Cervicitis causes a nondescript discharge with deep dyspareunia Chlamydia may cause a purulent vaginal discharge, post-coital spotting, and deep dyspareunia. Gonorrhea may cause a purulent vaginal discharge and deep dyspareunia. Cervical ectropion causes a mucous, asymptomatic discharge. Physical Exam Inspect carefully for the presence of lesions, foreign bodies and odor. Palpate to determine cervical tenderness. Yeast has a thick white cottage-cheese discharge and red vulva. Gardnerella has a foul-smelling, thin discharge. Trichomonas has a profuse, bubbly, frothy white discharge. Foreign body is obvious and has a terrible odor. Cervicitis has a mucopurulent cervical discharge and the cervix is tender to touch. Chlamydia causes a friable cervix but often has no other findings. Gonorrhea causes a mucopurulent cervical discharge and the cervix may be tender to touch. Cervical ectropion looks like a non-tender, fiery-red, friable button of tissue surrounding the cervical os. Infected/Rejected IUD demonstrates a mucopurulent cervical discharge in the presence of an IUD. The uterus is mildly tender. Chancroid appears as an ulcer with irregular margins, dirty-gray necrotic base and tenderness. Laboratory Obtain cultures for chlamydia, gonorrhea, and Strept. You may test the vaginal discharge in any of 4 different ways: Test the pH. If >5.0, this suggests Gardnerella. Mix one drop of KOH with some of the discharge on a microscope slide. The release of a bad-smelling odor confirms Gardnerella. Examine the KOH preparation under the microscope ("Wet Mount"). Multiple strands of thread-like hyphae confirm the presence of yeast. Mix one drop of saline with some discharge ("Wet Mount"). Under the microscope, large (bigger than WBCs), moving micro-organisms with four flagella are trichomonads. Vaginal epithelial cells studded with coccoid bacteria are "clue cells" signifying Gardnerella. Treatment In addition to specific treatment of any organism identified by culture or other test... Any patient complaining of an itchy vaginal discharge should probably be treated with an antifungal agent (Monistat, Lotrimin, etc.) because of the high likelihood that yeast is present, and Any patient complaining of a bad-smelling vaginal discharge should probably be treated with Flagyl (or other reasonable substitute) because of the high likelihood that Gardnerella is present. Ectropion, Erosion or Eversion This harmless condition is frequently mistaken for cervicitis. Ectropion, erosion or eversion (all synonyms) occurs when the normal squamo-columnar junction is extended outward from the its; normal position at the opening of the cervix. Grossly, the cervix has a red, friable ring of tissue around the os. Careful inspection with magnification (6-10x) will reveal that this red tissue is the normal tissue of the cervical canal, which has grown out onto the surface of the cervix. Cervical ectropion is very common, particularly in younger women and those taking BCPs. It usually causes no symptoms and need not be treated. If it is symptomatic, producing a more or less constant, annoying, mucous discharge, cervical cauterization will usually eliminate the problem. When faced with a fiery red button of tissue surrounding the cervical os, chlamydia culture (in high-risk populations) and Pap smear should be performed. If these are negative and the patient has no symptoms, this cervical ectropion should be ignored. Cervicitis Inflammation or irritation of the cervix is rarely the cause of significant morbidity. It is mainly a nuisance to the patient and a possible symptom of underlying disease (gonorrhea, chlamydia). Some patients with cervicitis note a purulent vaginal discharge, deep dyspareunia, and spotting after intercourse, while others may be symptom-free. The cervix is red, slightly tender, bleeds easily, and a mucopurulent cervical discharge from the os is usually seen. A Pap smear rules out malignancy. Chlamydia culture and gonorrhea culture (for gram negative diplococci) are routinely performed. No treatment is necessary if the patient is asymptomatic, the Pap smear is normal, and cultures are negative. Antibiotics specific to the organism are temporarily effective and may be curative. Cervical cautery may be needed to achieve permanent cure. Chlamydia This sexually-transmitted disease is caused by "chlamydia trachomatis". It very commonly locates in the cervical canal although it can spread to the fallopian tubes where it can cause PID. Most women harboring chlamydia will have no symptoms, but others complain of purulent vaginal discharge, deep dyspareunia, and pelvic pain. There may be no significant pelvic findings, but a friable cervix, mucopurulent cervical discharge, pain on motion of the cervix, and tenderness in the adnexa are suggestive. The diagnosis is often made on the basis of clinical suspicion but can be confirmed with chlamydia culture. Such cultures are frequently performed routinely in high-risk populations. Treatment is: Azithromycin 1 g orally in a single dose, OR Doxycycline 100 mg orally twice a day for 7 days, OR Erythromycin base 500 mg orally four times a day for 7 days, OR Erythromycin ethylsuccinate 800 mg orally four times a day for 7 days, OR Ofloxacin 300 mg twice a day for 7 days, OR Erythromycin base 250 mg orally four times a day for 14 days, OR Erythromycin ethylsuccinate 400 mg orally four times a day for 14 days. Foreign Body Lost and forgotten tampons are the most common foreign body found in the vagina, although other objects are occasionally found. Women with this problem complain of a bad-smelling vaginal discharge that is brown or black in color. The foreign body can be felt on digital exam or visualized with a speculum. As soon as you suspect or identify a lost tampon or other object in the vagina, immediately prepare a plastic bag to receive the object. As soon as it is retrieved, place it in the bag and seal the bag since the anaerobic odor from the object will be extremely penetrating and long-lasting. Have the patient return in a few days for follow-up examination. Normally, no other treatment is necessary, but patients who also complain of fever or demonstrate systemic signs/symptoms of illness should be evaluated for possible toxic shock syndrome, an extremely rare, but serious, complication of a retained tampon. Bacterial Vaginosis The patient with this problem complains of a bad-smelling discharge, which gets worse after sex. Cultures will show the presence of "Gardnerella Vaginalis," the bacteria associated with this condition. While this problem is commonly called "Gardnerella," it is probably the associated anaerobic bacteria, which actually cause the bad odor and discharge. The diagnosis is confirmed by the release of a bad odor when the discharge is mixed with KOH ("whiff test"), a vaginal pH greater than 5.0, or the presence of "clue cells" (vaginal epithelial cells studded with bacteria) in the vaginal secretions. Treatment is: Metronidazole 500 mg orally twice a day for 7 days, OR Clindamycin cream 2%, one full applicator (5 g) intravaginally at bedtime for 7 days, OR Metronidazole gel 0.75%, one full applicator (5 g) intravaginally twice a day for 5 days. OR Metronidazole 2 g orally in a single dose, OR Clindamycin 300 mg orally twice a day for 7 days. Gonorrhea This sexually-transmitted disease is caused by a gram negative diplococcus. The organism grows easily in the cervical canal, where it can spread to the fallopian tubes, causing PID. It may also infect the urethra, rectum or pharynx. Many (perhaps most) women harboring the gonococcus will have no symptoms, but others complain of purulent vaginal discharge, pelvic pain, and deep dyspareunia. There may be no significant pelvic findings, but mucopurulent cervical discharge, pain on motion of the cervix, and tenderness in the adnexa are all classical. The diagnosis is often made on the basis of clinical suspicion but can be confirmed with chocolate agar culture or gram stain. Treatment is: Cefixime 400 mg orally in a single dose, OR Ceftriaxone 125 mg IM in a single dose, OR Ciprofloxacin 500 mg orally in a single dose, OR Ofloxacin 400 mg orally in a single dose, PLUS Azithromycin 1 g orally in a single dose, OR Doxycycline 100 mg orally twice a day for 7 days. Sexual partners also need to be treated. Infected IUD Sooner or later, as many as 5% of all intrauterine devices will become infected. Patients with this problem usually notice mild lower abdominal pain, sometimes have a vaginal discharge and fever, and may notice deep dyspareunia. The uterus is tender to touch and one or both adnexa may also be tender. Treatment consists of removal of the IUD and broad-spectrum antibiotics. If the symptoms are mild and the fever low-grade, oral antibiotics (amoxicillin, cephalosporins, tetracycline, etc.) are very suitable. If the patient's fever is high, the symptoms significant or she appears quite ill, IV antibiotics are a better choice (cefoxitin, or metronidazole plus gentamicin, or clindamycin plus gentamicin). If an IUD is present and the patient is complaining of any type of pelvic symptom, it is wisest to remove the IUD, give antibiotics, and then worry about other possible causes for the patient's symptoms. IUDs can also be rejected without infection. Such patients complain of pelvic pain and possibly bleeding. On pelvic exam, the IUD is seen protruding from the cervix. It should be grasped with an instrument and gently removed. It cannot be saved and should not be pushed back inside. PID: Mild Gradual onset of mild bilateral pelvic pain with purulent vaginal discharge is the typical complaint. Fever <100.4 and deep dyspareunia are common. Moderate pain on motion of the cervix and uterus with purulent or mucopurulent cervical discharge is found on examination. Gram-negative diplococci or positive chlamydia culture may or may not be present. WBC may be minimally elevated or normal. Treatment consists of Doxycycline 100 mg PO BID x 10-14 days, plus one of these: Cefoxitin 2.0 gm IM with probenecid 1.0 gm PO, OR Ceftriaxone 250 mg IM, OR Ceftizoxime 1 gm IM, OR Cefotaxime 0.5 gm IM Alternative treatment includes: Ofloxacin 400 mg orally twice a day for 14 days, PLUS Metronidazole 500 mg orally twice a day for 14 days PID: Moderate to Severe With moderate to severe PID, there is a gradual onset of moderate to severe bilateral pelvic pain with purulent vaginal discharge, fever >100.4 (38.0), lassitude, and headache. Symptoms more often occur shortly after the onset or completion of menses. Excruciating pain on movement of the cervix and uterus is characteristic of this condition. Hypoactive bowel sounds, purulent cervical discharge, and abdominal dissension are often present. Pelvic and abdominal tenderness is always bilateral except in the presence of an IUD. Gram-negative diplococci in cervical discharge or positive chlamydia culture may or may not be present. WBC and ESR are elevated. Treatment consists of bedrest, IV fluids, IV antibiotics, and NG suction if ileus is present. Since surgery may be required, transfer to a definitive surgical facility should be considered. ANTIBIOTIC REGIMEN: (Center for Disease Control, 1998) Doxycycline 100 mg PO or IV every 12 hours, PLUS either: Cefoxitin, 2.0 gm IV every 6 hours, OR Cefotetan, 2.0 gm IV every 12 hours This is continued for at least 48 hours after clinical improvement. The Doxycycline is continued orally for 10-14 days. ALTERNATIVE ANTIBIOTIC REGIMEN: (Center for Disease Control, 1998) Clindamycin 900 mg IV every 8 hours, PLUS Gentamicin, 2.0 mg/kg IV or IM, followed by 1.5 mg/kg IV or IM, every 8 hours This is continued for at least 48 hours after clinical improvement. After IV therapy is completed, Doxycycline 100 mg PO BID is given orally for 10-14 days. Clindamycin 450 mg PO daily may also be used for this purpose. ANOTHER ALTERNATIVE ANTIBIOTIC REGIMEN: (Center for Disease Control, 1998) Ofloxacin 400 mg IV every 12 hours, PLUS Metronidazole 500 mg IV every 8 hours, ANOTHER ALTERNATIVE ANTIBIOTIC REGIMEN: (Center for Disease Control, 1998) Ampicillin/Sulbactam 3 g IV every 6 hours, PLUS Doxycycline 100 mg IV or orally every 12 hours. ANOTHER ALTERNATIVE ANTIBIOTIC REGIMEN: (Center for Disease Control, 1998) Ciprofloxacin 200 mg IV every 12 hours, PLUS Doxycycline 100 mg IV or orally every 12 hours, PLUS Metronidazole 500 mg IV every 8 hours. Trichomonas This microorganism, with its four flagella to propel it, is not a normal inhabitant of the vagina. When present, it causes a profuse, frothy white or greenish vaginal discharge. When the discharge is suspended in normal saline and examined under the microscope, the typical movement of these large organisms (larger than white blood cells) is obvious. Itching may be present, but this is inconsistent. Trichomonas is transmitted sexually and you may wish to treat the sexual partner, particularly if this is a recurrent trichomonad infection. Alternative treatments consist of: Flagyl, 250 mg TID for 7 days, OR Flagyl, 2 gm PO stat, OR Flagyl, 500 mg BID for 5 days Yeast (Monilia, Thrush) Vaginal yeast infections are common, monilial overgrowths in the vagina and vulvar areas, characterized by itching, dryness, and a thick, cottage-cheese appearing vaginal discharge. The vulva may be reddened and irritated to the point of tenderness. These infections are particularly troublesome in operational settings where they are both frequent and annoying. Yeast thrives in damp, hot environments and women in such circumstances are predisposed toward these infections. Women who take broad-spectrum antibiotics are also predisposed towards these infections because of loss of the normal vaginal bacterial flora. Yeast organisms are normally present in most vaginas, but in small numbers. A yeast infection, then, is not merely the presence of yeast, but the concentration of yeast in such large numbers as to cause the typical symptoms of itching, burning and discharge. Likewise, a "cure" doesn't mean eradication of all yeast organisms from the vagina. Even if eradicated, they would soon be back because that is where they normally live. A cure means that the concentration of yeast has been restored to normal and symptoms have resolved. The diagnosis is often made by history alone, and enhanced by the classical appearance of a dry, cheesy vaginal discharge. It can be confirmed by microscopic visualization of clusters of thread-like, branching Monilia organisms when the discharge is mixed with KOH. Treatment consists of Monistat 7 cream or any other anti-fungal agent (Mycelex, Lotrimin, Terazol, Femstat, nystatin, gentian violet, etc.) Oral Diflucan 150 mg orally once is also highly effective and well-tolerated. Whenever the skin of the vulva is involved, more frequent treatment for a longer period of time may be necessary. Reoccurrences are common and can be treated the same as for initial infections. For chronic recurrences, many patients find the use of a single applicator of Monistat 7 at the onset of itching will abort the attack completely. Sexual partners need not be treated unless they are symptomatic. Human Papilloma Virus Clinical Warts Condyloma acuminata, (venereal warts) are caused by a virus known as "Human Papilloma Virus" (HPV). There are two categories of warts, clinical and subclinical. Clinical warts appear as tiny, cauliflower-like, raised lesions around the opening of the vagina or inside the vagina. These lesions appear flesh-colored or white, are not tender and have a firm to hard consistency. If they are on the outside of the vagina or vulva, they are generally symptomatic, causing itching, burning, and an uncomfortable sensation during intercourse. If they are inside the vagina, they generally cause no symptoms. Subclinical Warts The second category, subclinical warts, are invisible to the naked eye, are flat and colorless. They usually do not cause symptoms, although they may cause similar symptoms to the raised warts. These subclinical warts can be visualized if the skin is first soaked for 2-3 minutes with vinegar (3-4% acetic acid) and then viewed under magnification (4-10X) using a green or blue (red-free) light source. Venereal warts are not dangerous and have virtually no malignant potential. Clinical warts may be a nuisance and so are usually treated. Subclinical warts are usually not treated since they are not a nuisance (most people with subclinical warts are unaware of their presence). Treatment Treatment consists of removal of the wart. This can be accomplished in any number of ways, some more painful than others can: Apply a small amount of bichloracetic acid (80-90%) directly to the wart, taking care to avoid spreading the acid onto the normal surrounding skin. For larger lesions, use a cotton-tipped applicator dipped in the acid. For smaller lesions, use the "stick" end of the cotton-tipped applicator. Apply enough acid (very tiny amounts) to cause the lesion to turn white, but not so much that it runs down onto the normal surrounding skin. No anesthetic is necessary. The patient may feel nothing, some slight tingling, or a minor stinging. After a minute or two, rinse the skin with warm water to dilute any remaining acid and prevent it from coming into contact with the surrounding skin. Try to use less acid than you think will be effective since the patient would rather return for a second, third or fourth treatment than recover from a serious acid burn of the vulva. Don't use acid inside the vagina or on the cervix. Cryosurgery can effectively remove warts. Freezing the wart with any convenient tool (liquid nitrogen, cryosurgical probe, etc.) can be done without anesthetic and results in sloughing of the wart in a week or two. Be careful not to freeze normal skin. Two freeze-thaw cycles usually work better than a single freeze-thaw cycle. Cryosurgery should not be done inside the vagina or on the cervix unless you have been specially trained to do this as damage to other structures can occur. Podophyllum resin can be applied directly to the wart, followed by washing off the residual podophyllin in 3-6 hours. This effective approach runs the risk of podophyllin toxicity. This is a minor issue if the wart is very small and you use tiny quantities of podophyllin. If you use large amounts, or apply it inside the vagina, toxicity is a real issue. Don't apply large amounts of podophyllin and don't apply any inside the vagina or on the cervix. Under anesthetic, warts can be surgically removed, burned, or electrocuted, but such methods are usually unnecessary for the typical small wart(s). If untreated, many warts will gradually resolve and disappear spontaneously, but this may require many months or years. Remember that in treating the warts, you are actually destroying the patient's skin, which has responded in a strange and annoying way to the presence of the HPV. You are not getting rid of the HPV itself. Persistence of Virus HPV is a sexually-transmitted virus that usually causes no symptoms but occasionally causes warts. The virus spreads throughout the skin of the vulva and vagina (as well as the inner thighs and lower abdomen), where it disappears into the skin cells and usually remains dormant forever. Like many other viruses, if the patient's immune system allows the virus to grow, it can reappear and cause warts. This virus is extremely common, infecting as many as 1/3 of the adult, sexually-active population. There is no known way to eliminate the virus from all skin cells. Transmission Patients with HPV are contagious to others, but there is no effective way to prevent its spread. Some physicians recommend condoms, but because the virus is found in areas of the skin beyond the condom, this is not likely to be effective. Some physicians recommend aggressive treatment of all warts, in the belief that active warts are more contagious than inactive virus within the skin. This theory has not, so far, been proven to be true. Dysplasia While warts are not considered dangerous, HPV infection is associated with another skin change known as "dysplasia." Dysplasia means that the skin (mainly of the cervix) begins growing faster than it should. There are different degrees of dysplasia: mild, moderate and severe. None of these is malignant, but it is true that the next step beyond severe dysplasia is cancer of the cervix. About 1/3 of all adult, sexually-active women have been infected with HPV, but probably less than 10% will ever develop dysplasia. Most (90%) of those with dysplasia will have mild dysplasia which will either regress back to normal or at least will never progress to a more advanced stage. Relation to Cancer Most women (About 90%) with mild dysplasia of the cervix will never develop a more advanced problem, and often the abnormality regresses back to normal. Most women with moderate to severe dysplasia of the cervix, if left untreated, will ultimately develop cancer of the cervix. If treated, most of these abnormalities will revert to normal, making this form of cervical cancer largely preventable. Cervical dysplasia is usually a slowly-changing clinical problem. There is indirect evidence to suggest that on average, it takes about 10 years to advance from normal, through the various stages of dysplasia, and into cancer of the cervix. Of course, any individual may not follow these rules. In providing medical care to women with cervical dysplasia, good follow-up is important, but urgent medical evacuation is usually not indicated for less threatening categories of dysplasia. Evaluation In any patient with venereal warts (condyloma), you should look for possible dysplasia of the cervix. This is best done with colposcopy, but a simple Pap smear can be very effective. Because HPV causes warts and is also associated with dysplasia, more frequent Pap smears (every 6 months) is a wise precaution, at least initially. If dysplasia is found, gynecologic consultation will be necessary, although this may be safely postponed for weeks or months if operational requirements make consultation difficult. The Vulva General The vulva is a portal for a variety of functions (reproductive and excretory) and has a unique role in sexual feelings and function.  Because it is covered with both dry, squamous skin and moist mucous membrane, it is subject to diseases affecting both. Because of the close proximity of the rectum, intestinal bacteria (anaerobes and coliforms) are more or less constantly present to some degree. These may influence the type and course of infections in this area. The vulva may develop conditions benign and malignant, symptomless, annoying, or even disabling Bartholin Cyst and Abscess The Bartholin glands are located on each side of the vaginal opening at the level of the posterior fourchette. Normally, they are neither visible nor palpable. Bartholin cysts are painless swellings in the labia majora. They are not infected and can be safely watched. They may occur following trauma or infection, but many are essentially spontaneous. It is a relatively simple procedure to drain them, but in operational settings, there is little need to do that as they are generally without symptoms. When infected (Bartholin abscess), the labia majora becomes excruciatingly painful. Some of these will drain spontaneously within 72 hours. Warm moist dressings or sitz baths may hasten this process. Incision and Drainage of the abscess gives immediate relief. Give local anesthetic of 1% Xylocaine over the incision site (thin area of skin medial to the cyst). Steady the cyst or abscess with one hand while a scalpel is directed into the center of the abscess. Purulent drainage should be cultured for gonorrhea. Antibiotic therapy is optional but wise, particularly if the patient is febrile, the abscess large, or the skin is red or tender. Recurrent Bartholin abscesses are common and these may need surgical removal, marsupialization, or insertion of a Word Catheter. A gynecologic surgeon best handles these. In an isolated military setting, a simple incision and drainage procedure will always be temporarily effective and is a reasonable choice. Chancroid This sexually-transmitted illness begins as a tender, reddened papule filled with pus. It then breaks down, ulcerates and reveals a grayish, necrotic base with jagged, irregular margins.  There is no significant induration around the base, unlike primary syphilis. In untreated cases, the lesions may spread and substantial tissue damage may result. Tender, enlarged inguinal lymph nodes are found in 50% of patients. Hemophilus ducreyi, the causative organism, is difficult to culture, so the diagnosis is made on the basis of history, physical exam and exclusion of other ulcerative diseases of the vulva. A gram-stain from the base of a clean ulcer or aspirate from a bubo may reveal a gram-negative coccobacillus clustered in groups around polymorphonucleocytes ("school of fish " appearance). Good choices for treatment include any of the following: Azithromycin 1 g orally in a single dose, Ceftriaxone 250 mg intramuscularly (IM) in a single dose, Ciprofloxacin 500 mg orally twice a day for 3 days, Erythromycin base 500 mg orally four times a day for 7 days. Condyloma Lata These skin lesions are associated with secondary syphilis and resemble condyloma acuminata (venereal warts), except their surface is smooth. They are raised, painless, flat lesions. Examination of the surface scrapings under darkfield microscope will show the typical spirochetes. Serologic test for syphilis (VDRL, RPR) will be positive.  Optimal treatment is: Benzathine penicillin G 2.4 million units IM in a single dose For those allergic to penicillin, you may substitute: Doxycycline 100 mg orally twice a day for 2 weeks, or Tetracycline 500 mg orally four times a day for 2 weeks. If the patient is pregnant, tetracyclines should not be used. Should the pregnant patient also be allergic to penicillin, desensitization is recommended by many, but operational circumstances may not allow for that. In such cases erythromycin or Azithromycin can be effective, although the optimal dosage is unknown. The main concern here is that if insufficient antibiotic gets across the placenta and to the fetus, fetal syphilis will be insufficiently treated. Contact Dermatitis A variety of chemical substances can cause local irritation of the skin. The vulva, because of its' mucous membrane and confined space, is more sensitive to these chemicals than many other areas of the body. Perfumes, soaps, detergents, feminine hygiene products, contraceptives (latex, creams, jellies), and medications have all been the cause of vulvar contact dermatitis. Contact dermatitis presents as a raised, itchy, red lesion in the area of contact with the irritating substance. The areas where skin touches skin are particularly sensitive since the irritating substance is held in place by the opposing skin surfaces. This creates a "butterfly" shaped rash in many patients. Treatment consists of identifying and eliminating the irritating substance. In severe cases, Burrow's Solution soaks will provide immediate relief and topical steroid cream will give intermediate term relief. Epithelial Polyp These painless, soft, fleshy, innocent growths arise from the labia majora. They are dry, non-tender and usually stable over many years. They can be safely ignored. If the patient finds one annoying, it is easily removed. However, in many operational settings, the risk of subsequent infection might outweigh the convenience of removing the polyp. Granuloma Inguinale This is a chronic, progressive, ulcerative, sexually-transmitted disease, involving the vulva, vagina or cervix. The initial lesion is a papule that undergoes central necrosis to form a clean, granulomatous, sharply-defined ulcer. This process continues, with development of multiple, confluent ulcers, which may be painful or painless. The ulcers have a beefy red base that bleeds easily. Pseudobuboes in the groin can be felt. The diagnosis is confirmed with biopsy of the ulcer, showing Donovan bodies on H&E stain or Giemsa stain. This condition is rare in the United States, but somewhat more common in the tropical areas of southern Africa, India and New Guinea. Treatment is Trimethoprim-sulfamethoxazole one double-strength tablet orally twice a day for a minimum of 3 weeks, or Doxycycline 100 mg orally twice a day for a minimum of 3 weeks, or Ciprofloxacin 750 mg orally twice a day for a minimum of 3 weeks, or Erythromycin base 500 mg orally four times a day for a minimum of 3 weeks. Therapy should be continued until all lesions have healed completely. Prognosis is excellent when treated in its early stages. Delayed treatment is associated with extensive scarring of the vulva, rectum and groin. Herpes Vulvitis A tingling or itching sensation precedes the development of painful blisters on both sides of the vulva in acute herpes infection. The blisters then break open, releasing clear fluid, and form shallow ulcers, filled with grayish material. The ulcers then crust over and when the crusts fall off, the underlying skin looks normal. The process takes 7-10 days. During the ulcerative stage, the pain may be so intense as to require narcotic analgesia. Urinating during this time can be extremely painful due to the hot, salty urine coming in contact with the open sores on the vulva. The pain may be so intense as to require such measures as urinating into a sitz bath or even placement of an indwelling urinary catheter (Foley). The diagnosis is made by the typical appearance and may be confirmed with a herpes culture. Although this lesion resolves spontaneously, re-occurrences are common. Preferred treatment (CDC) for an initial outbreak is: Acyclovir 400 mg orally three times a day for 7-10 days, OR Acyclovir 200 mg orally five times a day for 7-10 days, OR Famciclovir 250 mg orally three times a day for 7-10 days, OR Valacyclovir 1 g orally twice a day for 7-10 days. Preferred treatment (CDC) for a recurrence is: Acyclovir 400 mg orally three times a day for 5 days, OR Acyclovir 200 mg orally five times a day for 5 days, OR Acyclovir 800 mg orally twice a day for 5 days, OR Famciclovir 125 mg orally twice a day for 5 days, OR Valacyclovir 500 mg orally twice a day for 5 days. Some individuals have frequent recurrences, as often as every several weeks. For these women, "suppressive therapy" can be very helpful. Suppressive therapy involves taking relatively low doses of anti-viral medication daily, in order to keep the virus from causing such frequent attacks. Suggested regimens (CDC) for suppressive therapy include: Acyclovir 400 mg orally twice a day, OR Famciclovir 250 mg orally twice a day, OR Valacyclovir 250 mg orally twice a day, OR Valacyclovir 500 mg orally once a day, OR Valacyclovir 1,000 mg orally once a day. Another component of a herpes outbreak can be a bacterial superinfection. During the ulcerative stage, skin bacteria (strep, staph, and coliforms) can attack the exposed ulcers, causing a bacterial infection of the ulcer. This is particularly true of large or multiple, confluent ulcers. These women may benefit (faster recovery and less pain) by the use of antibiotics such as amoxicillin, any cephalosporin or erythromycin, even though those drugs will have no effect on the course of the viral component of the herpes. Hypertrophic Vulvar Dystrophy Hypertrophic vulvar dystrophy means the skin of the vulva has grown thicker than it should be. Associated with this thickening are the symptoms of intense itching and burning. These cases present clinically as patients with vulvar itching, initially believed to be yeast, which have failed to respond to standard anti-fungal therapy. On close inspection, the skin has a patchy white discoloration. A vulvar biopsy confirms the diagnosis. Treatment is topical steroids, used to thin the skin and relieve the symptoms. Vulvar biopsy is very important in these cases since differentiating visually between Hypertrophic vulvar dystrophy, lichen sclerosis, and VIN (vulvar intraepithelial neoplasia) is difficult and the treatments are very different. Further, mixed dystrophies (hypertrophic in some areas, and lichen sclerosis in other areas.) are common. Inclusion Cyst Inclusion cysts are common, innocent, symptomless swellings at the introitus of the vulva.  They are often a result of healing of an episiotomy or vulvar laceration following vaginal delivery but can occur spontaneously. An epithelial gland just beneath the skin, which normally would drain its' secretions to the surface of the skin, becomes trapped beneath the skin. Secretions accumulate, forming a small cyst. These cysts have a very thin skin covering and often, visible blood vessels can be seen coursing across the cyst. No treatment is necessary, but for a woman who finds the cyst annoying, it can be opened and drained. While it could re-form, it usually won't. Draining of this type of cyst might not be considered a good idea in some operational settings because the risk of infection at the incision site. Itching At least 90% of all women who complain of vaginal or vulvar itching will have yeast as at least a portion of the problem. Because of this, simply treating these patients with a reliable anti-fungal agent (Monistat, Mycelex, Lotrimin, Diflucan, etc.) without a detailed history, physical and laboratory evaluation, is often expedient and successful. In many operational settings, this therapeutic approach is particularly useful as it requires no laboratory or physical examination. For those in whom itching persists, a careful history and physical exam will usually be needed to determine the cause of the itching. When available, some tests which may be used in determining the cause of the itching, including vaginal cultures (for strep), wet mount (for yeast, Trichomonas and bacterial vaginosis), vulvoscopy (magnified inspection of the vulva) and directed skin biopsies. Less common causes of vulvar itching include hypertrophic vulvar dystrophy, lichen sclerosis, HPV, Paget's disease, VIN, contact dermatitis, psoriasis of the vulva and lice. Labial Abscess A labial abscess presents as a firm, very tender, reddened, unilateral mass.  The mass arises from the upper portion of the labia, in contrast to Bartholin cyst abscesses that arise from the lower (inferior) portion of the labia. Causes include infectious complications of trauma and infected skin glands. Many of these will drain spontaneously, but a simple incision and drainage procedure will provide dramatic, immediate relief of symptoms. Make the incision through the thinnest portion of the abscess wall, but this will generally be in the inferior, medial aspect of the mass. While antibiotics may be optional in a civilian setting, they are usually very desirable in an operational setting. Good choices include any antibiotic with reasonable effectiveness against common skin organisms (amoxicillin, cephalosporins, erythromycin, Azithromycin, clindamycin). Complete resolution of symptoms and restoration of the normal anatomy is the expected outcome. Lichen Sclerosis Lichen sclerosis is one form of vulvar dystrophy. With lichen sclerosis, the skin of the vulva is too thin. Clinically, women with lichen sclerosis complain of chronic vulvar itching and irritation. Tissues may be fragile, tear easily and result in superficial bleeding. Using only casual observation, the vulva may appear normal, but closer inspection will reveal a whitish discoloration and loss of anatomic differentiation of the vulvar structures. It may be difficult, without a vulvar biopsy, to distinguish lichen sclerosis from the other forms of vulvar dystrophy (hypertrophic vulvar dystrophy and mixed dystrophy). For this reason, women suspected of having lichen sclerosis usually undergo vulvar biopsy to confirm the diagnosis. Lichen sclerosis can occur in any age group, is not related to lack of estrogen, and its' cause is not known. As a general rule, topical steroids give only very limited relief and if used for any length of time (more than 2 weeks) can make the condition worse because they tend to thin the skin even more. The important exception to this rule is the topical synthetic fluorinated corticosteroid, Clobetasol, which has been very effective in eliminating symptoms and restoring the normal anatomy of the vulva. 0.05% clobetasol propionate cream is applied to the vulva twice daily for one month, than at bedtime for one month and then twice a week for three months. It is then used as needed one or two times per week. Using this approach, 95% of patients will notice significant improvement and 75% will report complete remission of symptoms. Traditional therapy consists of 2% testosterone propionate in petroleum jelly, applied 3 times a day for 3 to 6 months or until the symptoms are relieved. Then the applications are gradually reduced to a level of one or two applications per week. LGV Lymphogranuloma venereum is an uncommon sexually-transmitted disease caused by a variant of Chlamydia trachomatis. Following initial exposure, there is mild, blister-like formation that is frequently unnoticed. Within the following month, there is ulceration of the vaginal, rectal or inguinal areas. At this stage, the disease is very painful, particularly with walking, sitting and with bowel movements. The stool may be blood-streaked. Hard tender masses (buboes) arise in the inguinal area at this stage and are characteristic of the disease. As the disease progresses untreated, extensive scarring in the rectal area may require surgery to enable normal bowel movements. Scarring in the vaginal area can lead to painful intercourse or make intercourse basically impossible. Confirmation of the disease is optimally achieved with a positive Chlamydia trachomatis serotype culture from a bubo. Often, less specific tests, such as serum complement fixation test with acute and convalescent samples are used. In many operational settings, none of these tests are available and history of exposure, visual appearance of the lesions and known prevalence in the population make the diagnosis. Optimal treatment is: Doxycycline 100 mg orally twice a day for 21 days, or Erythromycin base 500 mg orally four times a day for 21 days. Because Azithromycin is effective against other presentations of Chlamydia trachomatis, it is likely, but unproven that use of multiple doses over several weeks would be effective against LGV. Melanosis Melanosis is the benign pigmentation of the mucosal surface of the vulva. The areas are multiple, flat, and stable. Biopsy, if performed, will show clusters of melanocytes with a benign appearance. The cause is unknown but genetics presumably plays a role. Left alone, they will remain stable for long periods of time, but may fade following childbirth. As they do not pose a threat and are not a cosmetic issue, no treatment is necessary. Suspicious areas or areas that are rapidly changing should be biopsied. Molluscum Contagiosum This sexually-transmitted pox-virus causes small, benign skin tumors to grow on the vulva, which are usually symptomless.  The tumors appear as dome-shaped lumps, 1-2 mm in diameter with tiny dimples in their center, and contain a white, cheese-like material. Treatment involves scraping off the lesion with a sharp dermal curette, and then coagulating the oozing base with Monsel's solution or AgNO3 sticks and applying direct pressure. Cryosurgery is also effective, as is the application of tri-chloracetic or bichloracetic acid directly to the lesion (taking care not to disturb the surrounding normal skin.) Left alone, they will generally resolve spontaneously after 6-12 months, but the patient remains contagious for as long as she has them. Paget's Disease Paget's disease is a slowly growing malignancy of the skin of the vulva. Visually, Paget's disease looks like a very bad case of vulvar Monilia. However: It has an asymmetrical distribution over the vulvar skin, and It doesn't' get better with conventional anti-fungal agents. It has an eczematoid appearance, with dry, crusty skin in some areas, but moist and weepy in other areas. Contact bleeding is significant. The diagnosis is confirmed with a vulvar biopsy. It is usually treated successfully with local excision. Pediculosis Pubis Pubic lice (pediculosis pubis) is caused by the infestation of the pubic hair and skin by tiny organisms that are just at the limits of visibility without magnification. Pubic lice can be spread through sexual contact, close living quarters, or shared clothing. The patient will describe moderately intense itching and may say, "I think I see something moving down there."  Ideally, the patient is examined with good lighting and a magnifying lens. The lice can be seen moving along the shafts of the pubic hair. Individual "nits" can be seen. These are small, oval, gray eggs attached to the hairs. Brown discolorations of the skin, when closely examined, are seen to contain lice excrement deposited just beneath the skin. Without magnification, the brown spots can be seen, but most noticeable is the movement of the lice. Treatment may include: Nix cream (5% permethrin) applied to the vulvar skin and left in place for 6-12 hours before washing off. Kwell lotion or shampoo (1% lindane) once after showering and left in place for 10 minutes before rinsing. This may be repeated in 7 days if necessary. Do not use more often or longer than this as lindane has neurotoxicity potential. Mechanically removing nits and lice by combing the pubic hair with a fine toothed comb. Clothing and bed linens should be thoroughly washed and dried. Mattresses should be aired or vacuumed. Sources of cross-contamination (shared clothing, towels) eliminated. Sexual contacts should be treated. If conventional medication is not available, petroleum jelly, applied to the affected area may prove effective by suffocating the lice. Primary Syphilis The distinguishing symptom is a painless ulcer on the vulva, vagina or cervix. The ulcer is non-tender, has a well-defined border and smooth base. It starts as a macular lesion, forms a central papule, then erodes to form an ulcer crater. Regional lymph nodes are enlarged, firm, mobile, and painless.  The diagnosis is confirmed by darkfield examination of serous fluid from crater (looking for spirochetes), a VDRL or RPR test. Watch for the Herxheimer reaction beginning within a few hours of treatment, with fever, chills, malaise, headache and myalgia. It is treated with bedrest and aspirin and will disappear within 24 hours. Continue treatment. Optimal treatment is: penicillin G 2.4 million units IM in a single dose For those allergic to penicillin, you may substitute: Doxycycline 100 mg orally twice a day for 2 weeks, or Tetracycline 500 mg orally four times a day for 2 weeks. If the patient is pregnant, tetracyclines should not be used. Should the pregnant patient also be allergic to penicillin, desensitization is recommended by many, but operational circumstances may not allow for that. In such cases erythromycin or Azithromycin can be effective, although the optimal dosage is unknown. The main concern here is that if insufficient antibiotic gets across the placenta and to the fetus, fetal syphilis will be insufficiently treated. Runner's Rash Irritation or chafing from running or other vigorous, prolonged exercise.  Skin of the inner thigh is reddened, excoriated, and may be bleeding in severe cases. Treatment is local therapy, keeping the area clean, dry, and untraumatized by continued exposure to rubbing. Prevention consists of: Avoiding cotton underwear when engaged in vigorous, repetitive physical activity. It gets wet and soggy, becoming an abrasive mass that wears away at the skin. Use petroleum jelly to lubricate the area while running Scabies Scabies is a skin infection with small (1/2 mm) mites, Sarcoptes scabiei. The mites burrow into the skin, laying their eggs in a trail behind them. About a month after the infection, there is a hypersensitivity skin reaction, with raised, intensely itchy skin lesions, most noticeable at night. The burrows (tunnels) from the mites can be seen through the skin as thin, serpentine, scaly lines of up to 1 cm in length. They are most commonly found in the fingerwebs, elbows, axilla, and inner surface of the wrists. They are also seen commonly on the breast areolae of women and along the belt line and genitals of men. The infection is spread by skin-to-skin contact with an infected person. The diagnosis is made by visualizing a burrow and confirmed by microscopic visualization of the mite, ova or fecal pellets in scrapings of the burrow suspended in oil. Treatment is: 5% permethrin cream (Nix, Elimite) applied to the skin from the neck down and left in place for 10 to 14 hours before washing off. Itching may persist for up to one month and should not be viewed as an indicator of failed treatment. If permethrin is not available, 1% lindane(Kwell lotion or shampoo) once after showering and left in place for 10 minutes before rinsing. This may be repeated in 7 days if necessary. Do not use more often or longer than this as lindane has neurotoxicity potential. Diphenhydramine 25-50 mg PO every 6 hours will relieve some of the itching, but will make the patient sleepy. In severe cases, Prednisone 40 mg PO QD X 2 days, then 20 mg X 2 days, then 10 mg X 2 days will provide significant relief. This regimen should be used cautiously in operational environments as it will suppress the immune system, making the patient more vulnerable to other problems. Unlike pubic lice, Sarcoptes scabiei do not live long on clothing or bed linens. Skene's Gland A Skene's gland is on each side of the urethral opening. It is normally neither seen nor felt, although close inspection will reveal the pinpoint openings of these periurethral glands.  When infected, the Skene's gland will become enlarged and tender. A simple incision and drainage of the gland will generally result in complete resolution. Topical anesthetic (20% benzocaine, or "Hurricaine") can be applied to the cyst with a cotton-tipped applicator and allowed to sit for 3-4 minutes. A single stab wound by a scalpel opens the abscess and allows for drainage of the pus. Cultures, particularly for gonorrhea, should be obtained. While in a civilian setting, antibiotics would be optional (pending culture results), they are very helpful in an operational settings. Good choices for antibiotics would include those most helpful for treating urethritis: Cefixime 400 mg orally in a single dose, OR Ceftriaxone 125 mg IM in a single dose, OR Ciprofloxacin 500 mg orally in a single dose, OR Ofloxacin 400 mg orally in a single dose, PLUS Azithromycin 1 g orally in a single dose, OR Doxycycline 100 mg orally twice a day for 7 days. Tinea Cruris (Jock Itch) A raised, reddened, intensely itchy lesion in the areas of skin to skin contact in the groin is characteristic of Tinea Cruris, which is also known as "Jock Itch." It is caused by a fungal infection.  The diagnosis can be made on the basis of the typical appearance of the lesion, but can be confirmed by scraping the margin of the lesion and suspending the scrapings in KOH. A microscopic exam will reveal the typical threads of fungus. Treatment is any conventional anti-fungal agent. If topical treatments are used, it may take up to several weeks to achieve a cure, even when applied two or three times a day. The fungus resides beneath the keratinized layer of skin and it takes time and persistence for the anti-fungal agent to penetrate through the skin to get at the fungus. Prevention involves avoiding the predisposing factors of heat and moisture. VIN Vulvar Intraepithelial Neoplasia (VIN) is a premalignant condition, which if untreated can lead to invasive cancer of the vulva. In the cervix, premalignant changes occur (CIN I, CIN II and CIN III) which precede the development of invasive cancer by many months or years.  In the case of the vulva, the same principle applies, that there are premalignant changes that may ultimately lead to cancer of the vulva. The degree of change is similarly labeled, VIN I, VIN II and VIN III (also known as "carcinoma-in-situ). Clinically, these patients usually present with vulvar itching which does not respond to anti-fungal agents. Closer inspection visually will show the skin to have a white discoloration, which can be enhanced with the application of acetic acid. Milder forms of VIN may not be obvious visually and special testing, such as the use of Toluidine Blue staining, may be necessary to identify the area of abnormality. The diagnosis is confirmed with vulvar biopsy. Treatment involves local excision, or in selected cases, laser vaporization. Close follow-up is very important should there be persistence or recurrence of disease. Vulvar Cancer This erosive lesion is malignant and can present as vulvar bleeding from a friable external lesion. In it's more advanced form, it may ulcerate through the vaginal, rectal and bladder mucosa. Effective treatment requires the skills of a definitive care center. Vulvar Hematoma A vulvar hematoma is usually the consequence of a "straddle" injury. When a woman falls while straddling a fixed structure, such as chair, railing, sawhorse or fire hydrant, it is a common occurrence that the peri-clitoral vessels on one side or the other will be crushed against the pubic bone. This results in a vulvar hematoma.  Most of the vulvar enlargement is soft tissue swelling, but some is due to an encapsulated hematoma. Diagnosis is made on the basis of history of a fall and the typical physical findings of unilateral swelling and pain. Clinical management consists of: An icepack is placed over the perineum and left in place for 24-48 hours. This will help control the pain and limit swelling and further bleeding into the hematoma. A Foley catheter is inserted and left in place. The local swelling may be sufficient to impair voluntary voiding and the Foley is much easier to insert earlier in the process. Bedrest for several days to a week. Appropriate analgesia. Initially, this may need injectable narcotics. Later, oral narcotics and then NSAIDs will give satisfactory results. Dramatic resolution will occur. When completely healed in a few weeks, the vulva will look normal and function normally. Most of these hematomas will not require surgical exploration and drainage. If you explore them, in about half the cases, no bleeding point will ever be found. Opening them introduces bacteria into an otherwise sterile hematoma. Particularly in operational settings, ice, Foley and bedrest are usually better choices for treatment. In following these, it may prove useful to measure the hematoma with a tape measure to compare the size over time. As they are feeling less pain, patients will often feel that the hematoma is enlarging. Having objective measures of its' size will be very reassuring to the patient. Vulvar Dystrophy Vulvar dystrophy is the abnormal growth of the skin of the vulva, in a benign but symptom-provoking manner. There are two forms of vulvar dystrophy: Lichen sclerosis, in which the skin of the vulva is too thin, and Hypertrophic vulvar dystrophy, in which the skin of the vulva is growing too thick. A third form, mixed dystrophy, is a combination of both. Both forms are associated with vulvar itching (pruritus) and burning, not responsive to anti-fungals, antibiotics or other creams or salves. Both can cause a white discoloration of the skin. While very experienced examiners may be able to predict which form of vulvar dystrophy is present in a patient, based on observation alone, a vulvar biopsy is usually needed to confirm the diagnosis. Vulvar Vestibulitis Vulvar vestibulitis is a condition of uncertain cause, characterized by pain and burning in specific sites on the vulva. The pain is most noticeable during intercourse and is very consistent, both in character and location. The pain and tenderness is distributed in a U-shaped pattern around the introitus and includes the hymeneal remnants and up to 1 cm of skin exterior to the hymen. Visually, the tender areas are reddened and touching them gently with a cotton-tipped applicator will duplicate the pain they experience during intercourse (a positive "Q-Tip Test"). Biopsy of these tender areas will show a generalized inflammatory pattern of non-specific etiology. Some women with vestibulitis indicate they have always felt this discomfort during intercourse. Others seem to have acquired the condition. They have painless intercourse initially, and later develop the painful intercourse so characteristic of this condition. The diagnosis is based on the physical examination, with persistent areas of tenderness to touch, located in the U-shaped area surrounding the hymenal ring. Biopsy is neither necessary nor often done. Treatment is problematic. Antibiotics, anti-fungals, anti-virals, estrogens, and steroids are often used and are often found to be ineffective. Antioxalates (used with the theory that oxalates provoke a skin reaction in this area) are promoted by some, but randomized studies demonstrate them to be no better than placebo. Several studies have demonstrated the efficacy of surgical excision of the affected area (perineoplasty) in selected cases.. Yeast (Candida, Monilia) Vaginal yeast infections are common, monilial overgrowths in the vagina and vulvar areas, characterized by itching, dryness, and a thick, cottage-cheese appearing vaginal discharge. The vulva may be reddened and irritated to the point of tenderness. These infections are particularly troublesome in operational settings where they are both frequent and annoying. Yeast thrives in damp, hot environments and women in such circumstances are predisposed toward these infections. Women who take broad-spectrum antibiotics are also predisposed towards these infections because of loss of the normal vaginal bacterial flora. Yeast organisms are normally present in most vaginas, but in small numbers. A yeast infection, then, is not merely the presence of yeast, but the concentration of yeast in such large numbers as to cause the typical symptoms of itching, burning and discharge. Likewise, a "cure" doesn't mean eradication of all yeast organisms from the vagina. Even if eradicated, they would soon be back because that is where they normally live. A cure means that the concentration of yeast has been restored to normal and symptoms have resolved.  The diagnosis is often made by history alone, and enhanced by the classical appearance of a dry, cheesy vaginal discharge. It can be confirmed by microscopic visualization of clusters of thread-like, branching Monilia organisms when the discharge is mixed with KOH. Treatment consists of an oral antifungal agent, Fluconazole 150 mg oral tablet, one tablet in single dose, or intravaginal agents: Butoconazole 2% cream 5 g intravaginally for 3 days Clotrimazole 1% cream 5 g intravaginally for 7-14 days Clotrimazole 100 mg vaginal tablet for 7 days Clotrimazole 100 mg vaginal tablet, two tablets for 3 days Clotrimazole 500 mg vaginal tablet, one tablet in a single application Miconazole 2% cream 5 g intravaginally for 7 days Miconazole 200 mg vaginal suppository, one suppository for 3 days Miconazole 100 mg vaginal suppository, one suppository for 7 days Nystatin 100,000-unit vaginal tablet, one tablet for 14 days Tioconazole 6.5% ointment 5 g intravaginally in a single application Terconazole 0.4% cream 5 g intravaginally for 7 days Terconazole 0.8% cream 5 g intravaginally for 3 days Terconazole 80 mg vaginal suppository, one suppository for 3 days. If none of these products are available, douching with a weak acid solution (2 teaspoons of vinegar in a quart of warm water) twice a day will help restore an acid pH to the vagina, inhibiting yeast proliferation. Stop douching when symptoms have resolved as the douche itself tends to remove some of the protective mucous within the vagina. Whenever the skin of the vulva is involved, more frequent treatment for a longer period of time may be necessary. Reoccurrences are common and can be treated the same as for initial infections. For chronic recurrences, many patients find the use of a single applicator of Monistat 7 at the onset of itching will abort the attack completely. Sexual partners need not be treated unless they are symptomatic. PRIVATE Problems with Menstruation Normal Menstrual Flows About once a month, women of childbearing age normal menstruate for 4-6 days, losing between 25 and 60 cc of blood. The blood is dark in color and mixed with mucous, inflammatory exudate, and cellular debris, representing the shed lining of the uterus. Day #1 of the menstrual cycle is designated as the first day of the menstrual flow. At approximately Day #14, one or the other ovaries releases an egg (ovulation), an event which may or may not be perceived by the woman. With ovulation, some women notice brief abdominal cramping while others do not. Some women notice a small amount of pink vaginal discharge or spotting, while others do not. Some women notice a significant, brief, increase in cervical mucous secretions (evidenced in vaginal discharge) but others do not. Following ovulation, progesterone, the other female hormone (other than estrogen) is produced in significant quantities. Progesterone has a number of functions, but in the normal menstrual cycle, continues to be produced by the ovary for 10-12 days. Following the abrupt fall in progesterone, a new menstrual flow is triggered, starting several days after the drop in progesterone. Cramps Menstrual cramps (dysmenorrhea) are among the most common of menstrual cycle symptoms. They may be mild, moderate or severe, and may not be consistent from one cycle to the next. They are usually midline and suprapubic. The cramps are waxing and waning in character but a constant dull ache is also common. The pain may radiate into the back or upper anterior thighs. The cramps typically begin a day or two prior to the menstrual flow and are usually resolved before the menstrual flow has finished, although there is considerable person-to-person variation. Simple cramps usually respond well to simple measures. Any of the nonsteroidal anti-inflammatory agents (Ibuprofen, naproxen, etc.) can be effective, but sufficiently high doses are most effective. A loading dose of ibuprofen, 800 mg PO can be started a day prior to the anticipated onset of cramps. This is followed by 600 mg PO every 8 hours for as long as the cramps persist. If you wait until cramps have already begun to start the NSAIDs, they will not be as effective, but may still prove useful. Regular exercise has been demonstrated to reduce the frequency and severity of menstrual cramps, probably through the release of internal beta-endorphins. More severe menstrual cramps usually respond very well to BCPs. Possibly through blocking of ovulation and also perhaps by the reduction in amount and duration of bleeding, BCPs are a first-line treatment for significant dysmenorrhea. Any of the low-dose, monophasic BCPs can be employed for this purpose. Significant relief should be expected after the first BCP-induced flow and additional improvement over the next 6 months may continue. For those women with severe cramps whose symptoms are not improved with BCPs, continuous BCPs may provide the solution. In this case, the BCPs are taken without letup (continuously) and there is no menstrual flow at all. Without a menstrual flow, menstrual cramps are inhibited. For these women, gynecologic consultation while in garrison is probably wise to evaluate such patients for the possible presence of endometriosis. Breast Pain For some women, cyclic breast pain and tenderness (mastodynia or cyclic mastalgia) accompanies the later portions of the menstrual cycle. Typically for several days preceding the menstrual flow, the breasts of these women enlarge, become lumpy, tender to touch, and produce a generalized aching. The nipples may become extremely sensitive and very uncomfortable. This condition is sometimes called fibrocystic breast disease, fibrocystic breast changes, or cyclic mastalgia. Very mild cases of mastodynia can be treated with mild analgesics and reassurance. The more severe forms respond well to a number of medications; The simplest of these is BCPs. After starting low-dose, monophasic BCPs, the cyclic breast pain is usually immediately improved to some extent. In the months and years to come, the breasts usually become progressively less lumpy, less tender and less uncomfortable. BCPs are a very effective long-term treatment for this problem. Also effective is the use of Danazol. Unfortunately, Danazol (800 mg/day) is expensive, not often available in operational settings, and has many significant side effects (unwanted hair growth, deepening of the voice, weight gain, clitoral hypertrophy, and others), which limit its' usefulness. If these medications are unavailable, probably any medication which disrupts ovulation, such as Lupron, or DEPO-PROVERA, will be reasonably effective in stopping the cyclic breast pain that is so annoying to some women. Midcycle Pain Midcycle pain ("mittelschmerz") is the pain that can accompany ovulation. Typically occurring on about Day #14, the pain is unilateral, may occur on either side, and lasts for a few hours to a day or two. It is not known why this ovulatory pain is so disabling to some women, is minor in other women, and not even felt by still other women. The treatment of mild cases is usually reassurance and oral analgesics during the pain. For more significant symptoms, BCPs generally work very well at inhibiting ovulation and preventing the pain. Other alternatives include any medication, which would interfere with ovulation, such as DEPO-PROVERA, or Lupron. The latter two, while effective, often have so many other side effects that the treatment is worse than the problem. Acne Acne is caused by a combination of hereditary predisposition (genetic factors) and stimulation of skin glands by male hormones. Both men and women produce both male and female hormones, but men mainly produce male hormones and women mainly produce female hormones. In the second half of the menstrual cycle, particularly as menstruation is approaching, there is a fall in the amount of estrogen (female hormone), although the small amount of male hormone remains more or less constant. This results in a relative increase in the influence of the small amount male hormone present. In the susceptible woman, this will lead to increased acne just before the menstrual flow. BCPs are usually effective in treating this. In fact, BCPs are usually helpful in treating acne in general, primarily because of the suppression of ovarian function. Since the ovaries produce about a third of all male hormone in women, this drop in male hormone levels is often sufficient to lead to improvement in acne. Occasionally, (uncommonly) the BCPs aggravate the acne, and in these cases, the BCPs should be switched or stopped altogether. While some evidence suggests that Ortho-Cyclen and Demulen 1/35 may be more effective against acne than the other BCPs, good results can likely be obtained from any of them. Headache Headaches may accompany the menstrual cycle and present in a number of ways. Menstrual migraine headaches are common and temporarily disabling. They usually occur just before the onset of a menstrual flow or during the first day. They are triggered, in susceptible individuals, by the sudden drop in hormones accompanying the premenstrual phase. Good success in treating menstrual migraines can usually be achieved through the use of BCPs: In some cases, low-dose monophasic BCPs are effective at suppressing the menstrual migraines. In some cases, the 7 days "off" BCPs each month is too long and the accompanying hormone changes trigger the headaches. These women do well for a few days during their "off" week, but then develop headaches at the end of the week. For these women, shortening the "off week" to only 3 days will frequently provide them relief from their menstrual migraines. There is still a change in hormones, but about the time the menstrual migraine is going to begin, the reinstitution of the BCPs prevents the migraines from starting. In some cases, it will be necessary to go to continuous BCPs to achieve good migraine suppression. In some cases, BCPs are not effective in controlling the menstrual migraines and other treatments must be used. Sinus headaches may be more pronounced during the days leading up to the menstrual cycle, due to changes in hormone levels and their impact on sinus mucosa and fluid retention. These headaches have their focus of pain in the paranasal sinuses, which become sensitive to direct digital pressure, and also by the indirect pressure of putting the head down between the knees. In addition to the usual methods of treating sinus headaches (analgesics, decongestants, antihistamines, antibiotics, as appropriate), cyclic symptoms can often be controlled by BCP suppression of ovulation. Tension or stress headaches may also worsen or improve, depending on the menstrual cycle. In these cases, hormone changes or fluid retention may play a role in the development of such headaches in susceptible individuals. BCPs can often improve these headaches, although occasionally, the BCPs may aggravate them. A therapeutic trial of BCPs is often undertaken. Fluid Retention The fluid retention just prior to menses usually amounts to a pound or less of extracellular fluid collected in the dependent extremities and to a lesser degree in the breasts. Mild to moderate degrees of fluid retention are usually tolerated with reassurance while more dramatic forms are often treated. BCPs, by blocking ovulation and the accompanying hormonal changes are very effective at blocking the fluid retention elements of bloating. Alternatively, any diuretic can be used and generally has very dramatic, though very temporary effects. Used every other day for a few days, diuretics in reasonable doses will generally keep fluid retention to a minimum, but with some risk of salt imbalance. Used more frequently or for longer periods of time, the risks of electrolyte imbalance increase. In operational settings, the risks of diuretic therapy very often are greater than any potential benefits in other than very extreme cases. Abdominal Bloating Progesterone has a quieting effect on smooth muscle contractility. Largely for this reason, gastrointestinal function usually slows to some degree during the second half of the menstrual cycle. While most women do not notice the change, a few will notice bowel sluggishness, constipation, increased gas production and abdominal dissension. While this is not dangerous, it can be annoying. When combined with the natural tendency in many deployed settings to intentionally dehydrate (avoiding the problem of urination), constipation can become a quite significant problem. BCPs can block this change in gastrointestinal function by virtue of the inhibition of ovulation and the hormone changes that go along with ovulation. Increasing dietary fiber and fluid intake can also be helpful. In extreme cases in operational settings, bulk laxatives or bowel stimulants may prove necessary. Depression and Irritability It is not known why some women, as they approach their menstrual flow, experience these mood changes. For most women, these symptoms are either very mild or absent, while others have moderate or severe symptoms. For them, the symptoms may begin around the time of ovulation and persist until the menstrual flow has begun. For others, the mood changes are limited to a day or two preceding the menstrual flow. About 80% of women with moderate to severe premenstrual mood changes will obtain significant relief from BCPs. The blocking of ovulation seems to be the key element as very low dose pills or progestin-only pills do not seem to have the same effect. If BCPs are not available or the patient is not a good BCP candidate, any medication, which blocks ovulation, will likely have the same effect. Unfortunately, some of these medications (Lupron, DEPO PROVERA, and Danazol) have depression and irritability as potential side-effects, so the patient must be closely watched. Anti-depressant medications (Prozac, etc.) are also about 80% effective in improving the mood changes associated with the premenstrual syndrome. These are not, however, the same 80% who benefit from BCPs, so for BCP failures, a therapeutic trial of antidepressant medication may be considered. Whether such a trial is appropriate in an operational setting should be individually determined. Abdominal and Pelvic Pain Uncertainty of Diagnosis When treating a female patient with abdominal pain, I sometimes don't have a clue as to what the problem is. I say this as a board-certified OB-GYN, with more than 20 years in clinical practice, practicing in a 600-bed teaching hospital, with ultrasound, MRI scans, and full lab support. Sometimes all I can say is: "This patient is sick with something." Sometimes these patients get well before I can figure out the diagnosis. Sometimes these patients get worse and I end up performing surgery and find PID, or endometriosis, or an ovarian cyst or almost any other gynecologic, surgical or medical problem. Sometimes I do laparoscopy and find nothing abnormal, but the pain goes away. The First Point is: In clinical gynecology, the diagnosis is often unclear. Just because you're unsure of the diagnosis doesn't mean you can't take good care of the patient. Often you must treat the patient before knowing the diagnosis. The Second Point is: More important than knowing the correct diagnosis is doing the right thing for the patient. Pain and Bedrest If the patient has pelvic/abdominal pain or tenderness, placing her on bedrest for a few days will usually help and is never the wrong thing to do. For many of your patients, the pain will simply resolve (although you won't know why) Pain and Fever If the patient has a fever (in addition to her pain), I would recommend you give her antibiotics to cover PID. With mild pain and fever, oral antibiotics should work well, so long as they are effective against chlamydia (Doxycycline, tetracycline, erythromycin, Azithromycin , etc.). If the fever is high or the pain is moderate to severe, I would recommend IV antibiotics (such as clindamycin/gentamicin or cefoxitin or cefotetan or Flagyl/gentamicin) to cover the possibility of pelvic abscess. Chronic Pain If there is no fever, but your patient complains of chronic pelvic pain, a course of oral Doxycycline is wise. Some of these women will be suffering from chlamydia and you may cure them through the use of an antibiotic effective against chlamydia. Others will not improve and will need further evaluation by experienced providers in well-equipped settings. Pregnancy Test Any patient complaining of pelvic pain should have a pregnancy test. I am surprised at how often it is positive despite the patient saying "that's impossible." BCPs and Pain Most patients complaining of intermittent, chronic pelvic pain will benefit from oral contraceptive pills. BCPs reduce or eliminate most dysmenorrhea and have a favorable influence on other gynecologic problems such as endometriosis, ovarian cysts, and adenomyosis, a benign condition in which the uterine lining grows into the underlying muscle wall, causing pain and heavy periods. When using BCPs to treat chronic pelvic pain, multiphasic BCPs such as Ortho Novum 7/7/7, Triphasil or Tri-Norinyl have not been as effective as the stronger, monophasic BCPs such as LoOvral, Ortho Novum 1+35 or Demulen 1/35 (in my experience). I believe the reason is that the multiphasic pills, by virtue of their lower dose and changing dosage, do not suppress ovulation as consistently as the higher-dose pills. If the BCPs do not help or if the patient continues to have pain during her menstrual flow, change the BCP schedule so the patient takes a monophasic (LoOvral, 1+35, etc.) BCP every day. She will: not stop at the end of a pack. not wait one week before restarting. not have a menstrual flow. If she doesn't have a menstrual flow, she can't get dysmenorrhea. Taken continuously, BCPs are effective and safe. The only important drawback is that she will not have a monthly menstrual flow to reassure her that she is not pregnant. Because the birth control pills are so very effective in treating dysmenorrhea, the emergence of cyclic pelvic pain while taking BCPs is a worrisome symptom. Endometriosis can cause these symptoms. Happily, birth control pills, particularly if taken continuously, are a very effective treatment for endometriosis. Upon return to a garrison setting, women with pain while taking should be evaluated by an experienced gynecologic clinician. After a number of months, women on continuous BCPs will usually experience spotting or breakthrough bleeding. It is not dangerous. If this becomes a nuisance, stop the BCPs for one week (she'll have a withdrawal bleed), and then restart the BCPs continuously. Pregnancy and Bleeding Any pregnant patient who experiences bleeding should lie still (bedrest) until the bleeding stops for a few days. Then she may be moved to a definitive care setting (hospital). If she is destined to miscarry, having her lie still will not prevent the miscarriage, but it will probably postpone the miscarriage until she can be moved to a safe place where D&C capability is present. Threatened Abortion Patients who are less than 20 weeks pregnant and have cramping uterine pain are usually threatening to miscarry. Bedrest is a good idea for all these patients, not because it will prevent the miscarriage, but because it may postpone the miscarriage until the patient is in a location that can deal effectively with any complications. If medical evacuation is not an option, then bedrest will still help the woman tolerate the discomfort of the miscarriage. Of all women with a threatened abortion, about half will ultimately miscarry and about half will not. In the group who do not miscarry, the remainder of the pregnancy is usually uneventful and the baby will be expected to arrive at full term, alive and without disability Ectopic Pregnancy This is a pregnancy occurring outside the normal location (within the uterus). While these pregnancies will grow briefly, they are not viable and lead to pregnancy loss. The pregnancy loss can be nearly unnoticed (a "tubal abortion," with the pregnancy expelled out the end of the fallopian tube), but are more often very dramatic, with severe pain and bleeding. If the tube ruptures, extensive and sometimes fatal hemorrhage into the abdominal cavity occurs. Women with an ectopic pregnancy will almost always have a positive pregnancy test, often have vaginal bleeding, and may or may not have abdominal pain or tenderness. Right shoulder pain is an ominous sign, usually indicating extensive hemorrhage into the abdomen, with irritation of the phrenic nerve which courses along the undersurface of the right hemidiaphragm. In a hospital setting, a variety of treatments can be considered, including surgery, chemotherapy (methotrexate), and occasionally observation. In an isolated military setting, bedrest until a prompt medical evacuation to a surgical facility is most appropriate. Should medical evacuation to a surgical facility not be an available option, treatment is supportive, with IV fluids, bedrest, a MAST suit, and blood transfusions as needed. Most women managed with this supportive treatment will survive treatment, although some will not. Survivors should expect a lengthy, uncomfortable recovery. Oral iron therapy will help restore lost hemoglobin. Placental Abruption Patients who are more than 20 weeks pregnant who have constant pain in the uterus are probably experiencing a placental abruption (premature separation of the placenta), particularly if the uterus is tender. They may or may not have vaginal bleeding. When hospital care is available, these women are best evaluated by an obstetrician with the technologic resources of electronic fetal monitoring, ultrasound and a sophisticated laboratory testing. In isolated settings, bedrest with the patient lying on her left side and IV hydration are really the only options you have. If the pain improves with bedrest, keep the patient at rest. Consider transport later, after the pain resolves. If the pain shows no evidence of improving with rest, then you will need to transport her sooner since severe placental abruption may be fatal to the patient and/or her baby. Definitive treatment consists of cesarean section and treatment of the coagulopathy (bleeding disorder) that usually accompanies this problem. If neither definitive therapy (cesarean section) nor medical evacuation are available, the following generalizations can be made: With very mild cases, the contractions will usually go away with bedrest and the pregnancy will continue for a while (days to weeks) although early delivery is usually the rule. The ultimate outcome for mother and baby is generally good if the mild abruption is the only significant problem. For moderate degrees of placental abruption, the woman usually goes into premature labor and delivers. She generally does well, but the baby may be stillborn or severely incapacitated. For severe degrees of placental abruption, if the woman does not deliver very promptly, the abruption will likely prove fatal to her because of the marked coagulopathy that develops. If the baby is not delivered within 10 to 20 or 30 minutes of the severe abruption, it will likely be stillborn. Under these circumstances, supportive treatment (bedrest, IV fluids, and blood transfusions) may be lifesaving. Placenta Previa Any pregnant patient beyond the 20th week of pregnancy who is bleeding should lie still and YOU SHOULD NOT DO A PELVIC EXAMINATION UNLESS INSTRUCTED TO DO SO BY A CONSULTING OBSTETRICIAN. In most cases, the bleeding comes from a small placental abruption and will temporarily resolve with bedrest. Occasionally, the bleeding will be from a "placenta previa," a condition in which the placenta is located immediately behind the cervix. If you perform a pelvic exam on a patient with placenta previa, you may cause massive bleeding which you won't be able to stop without a cesarean section. Most bleeding in pregnant patients will stop temporarily with bedrest. If a definitive treatment center is close (a brief, smooth ambulance ride), then immediate transport of the patient is best. If a definitive treatment center is distant, it is probably better to stop the bleeding first with bedrest. Move her after a few days when the long and perhaps bumpy transport is less likely to re-start the bleeding. If the bleeding shows no sign of slowing despite bedrest, you may need to begin transport anyway. Should transport not be an available option: Continue the bedrest as long as there is any bleeding. Marginal placenta previas may resolve with time and successful vaginal delivery, while dangerous, can be successful. In this case, pressure from the fetal head on the placenta tends to compress or tamponade the loss of blood from the placenta long enough to achieve a successful delivery. In cases of a complete placenta previa, where the placenta totally covers the internal cervical os, maternal death during labor, due to intractable hemorrhage is the rule. IUD Problems Any woman with an IUD who has any symptoms of pelvic/abdominal pain or abnormal bleeding should first have the IUD removed. Depending on the circumstances, another IUD may be safely inserted at a later time, but the current IUD should be removed. If the pelvic pain is caused by a low-grade infection in the uterus, leaving the IUD in place may lead to a more serious infection and subsequent infertility Ovarian Cyst An ovarian cyst is a fluid-filled sac arising from the ovary. These cysts are common and generally cause no trouble. Each time a woman ovulates, she forms a small ovarian cyst (3.0 cm in diameter or less). Depending on where she is in her menstrual cycle, you may find such a small ovarian follicular cyst. Large cysts (>7.0 cm) are less common and should be followed clinically or with ultrasound. Occasionally, ovarian cysts may cause a problem by: Delaying menstruation Rupturing Twisting Causing pain 95% of ovarian cysts disappear spontaneously, usually after the next menstrual flow. Those that remain and those causing problems are often removed surgically. Ruptured Ovarian Cyst This is an ovarian cyst that has ruptured and spilled its' contents into the abdominal cavity. If the cyst is small, its' rupture usually occurs unnoticed. If large, or if there is associated bleeding from the torn edges of the cyst, then cyst rupture can be accompanied by pain. The pain is initially one-sided and then spreads to the entire pelvis. If there is a large enough spill of fluid or blood, the patient will complain of right shoulder pain. Symptoms should resolve with rest alone. Rarely, surgery is necessary to stop continuing bleeding. Unruptured Ovarian Cyst While most of these have no symptoms, they can cause pain, particularly with strenuous exercise or intercourse. Treatment is symptomatic with rest for those with significant pain. The cyst usually ruptures within a month. Once ruptured, symptoms will gradually subside and no further treatment is necessary. If it doesn't rupture spontaneously, surgery is sometimes performed to remove it. This will relieve the symptoms and prevent torsion. Torsioned Ovarian Cyst A torsioned ovarian cyst occurs when the cyst twists on its' vascular stalk, disrupting its' blood supply. The cyst and ovary (and often a portion of the fallopian tube) die and necrose. Patients with this problem complain of severe unilateral pain with signs of peritonitis (rebound tenderness, rigidity). This problem is often indistinguishable clinically from a pelvic abscess or appendicitis, although an ultrasound scan can be helpful. Treatment is surgery to remove the necrotic adnexa. If surgery is unavailable, then bedrest, IV fluids and pain medication may result in a satisfactory, though prolonged, recovery. In this suboptimal, non-surgical setting, metabolic acidosis resulting from the tissue necrosis may be the most serious threat. Mortality rates from this condition (without surgery) are in the range of 20%. Other surgical conditions which may resemble a twisted ovarian cyst (such as appendicitis or ectopic pregnancy) may not have a good outcome if surgery is delayed. For this reason, patients thought to have a torsioned ovarian cyst should be moved to a definitive care setting where surgery is available. Dysmenorrhea Painful menstrual cramps. These midline, lower abdominal, suprapubic cramps or aches usually begin shortly before the beginning of menses and can persist for a few days into the menstrual flow. Then complete relief occurs and the patient remains pain-free until the next month. This is not a dangerous condition but can be a powerful nuisance to the patient. The single most effective medication to treat this is oral contraceptive pills (fixed-dose or monophasic BCPs like LoOvral, 1/35s, etc.) Standard doses of non-steroidal anti-inflammatory agents such as naproxen or ibuprofen can be helpful. Exercise, through the release of beta endorphins, is helpful to some. Patients with endometriosis may also complain of monthly pain. If the symptoms are severe and do not respond to BCPs (cyclic or continuous), or NSAIDs, then endometriosis is usually looked for with diagnostic laparoscopy at an opportune time. Mittelschmerz Pain associated with ovulation (from German: "middle pain") which typically occurs at mid-cycle...half way between the menstrual flows. The pain is either right or left-sided, depending on which ovary released the egg that month. Women do not usually alternate sides, but rather randomly ovulate: sometimes one side, sometimes the other. The pain, when it occurs, is mild to moderate. There may be some mild peritoneal signs. By the time the patient is examined, the pain is often improving. If the symptoms are severe or last more than a day or two, consider other diagnoses such as ovarian cyst, ectopic pregnancy or endometriosis. Treatment is supportive. Usually a day or two of rest will see the complete resolution of symptoms. Rarely the symptoms last longer. Any mild analgesic will make them feel better. Birth control pills usually provide complete relief through their inhibition of ovulation. Functional Bowel Syndrome Intermittent cramping abdominal pain, associated with episodes of constipation or diarrhea, with or without mucous stools. Patients with this problem give a history of periodically recurring symptoms, often provoked by stress. X-ray evaluation of the abdomen will show no abnormality and all lab studies will be normal. The pain will move from place to place in the abdomen. Treatment is generally supportive with reduction of stress when that is possible. Avoiding (or treating) constipation or diarrhea is helpful. Non-narcotic analgesics can be given if the pain is quite significant. Antispasmodics are sometimes helpful. Psychoactive drugs are inadvisable unless a specific psychological disorder is present which would be expected to respond to the psychoactive drug. Gastroenteritis Acute inflammation of the stomach and intestines, resulting in cramping abdominal pain, distention, nausea, vomiting, diarrhea, fever, and chills. This may be due to bacterial infection, viral infection, or ingestion of a toxic substance (food poisoning). Patients usually complain of diffuse, cramping abdominal pain with marked GI symptoms. The pain migrates from place to place. Treatment is mostly supportive (rest and observation in mild cases, IV fluids in severe cases) with specific antibiotic therapy when the causative organism is known and sensitive to this approach. Diverticular Disease Diverticular disease represents a spectrum of abnormalities ranging from asymptomatic "diverticula" (small outpouchings of the colon) to "diverticulitis" with peritonitis, abscess formation and sometimes perforation of the colon. Diverticular disease is usually focused in the sigmoid colon in the left lower quadrant, although diverticula can be found in small numbers anywhere along the course of the large and small intestines. Cramping lower abdominal pain with diarrhea alternating with constipation are symptoms common to those with diverticular disease (and also functional bowel syndrome). If accompanied by fever and elevated white blood count with a mass in the left lower abdomen, "diverticulitis" is likely to be present. Mild symptoms require only supportive treatment. Diverticulitis often requires IV fluids and antibiotics. PID Pelvic Inflammatory Disease (PID) is a bacterial inflammation of the fallopian tubes, ovaries, uterus and cervix. Initial infections are caused by single-agent STDs, such as gonorrhea or chlamydia. Subsequent infections are often caused by multiple non-STD organisms (E. Coli, Bacteroides, etc.). From a clinical management point of view, there are two forms of PID: Mild, and Moderate to Severe PID: Mild Gradual onset of mild bilateral pelvic pain with purulent vaginal discharge is the typical complaint. Fever <100.4 and deep dyspareunia are common. Moderate pain on motion of the cervix and uterus with purulent or mucopurulent cervical discharge is found on examination. Gram-negative diplococci or positive chlamydia culture may or may not be present. WBC may be minimally elevated or normal. Treatment consists of Doxycycline 100 mg PO BID x 10-14 days, plus one of these: Cefoxitin 2.0 gm IM with probenecid 1.0 gm PO, OR Ceftriaxone 250 mg IM, OR Ceftizoxime 1 gm IM, OR Cefotaxime 0.5 gm IM Alternative treatment includes: Ofloxacin 400 mg orally twice a day for 14 days, PLUS Metronidazole 500 mg orally twice a day for 14 days PID: Moderate to Severe With moderate to severe PID, there is a gradual onset of moderate to severe bilateral pelvic pain with purulent vaginal discharge, fever >100.4 (38.0), lassitude, and headache. Symptoms more often occur shortly after the onset or completion of menses. Excruciating pain on movement of the cervix and uterus is characteristic of this condition. Hypoactive bowel sounds, purulent cervical discharge, and abdominal dissension are often present. Pelvic and abdominal tenderness is always bilateral except in the presence of an IUD. Gram-negative diplococci in cervical discharge or positive chlamydia culture may or may not be present. WBC and ESR are elevated. Treatment consists of bedrest, IV fluids, IV antibiotics, and NG suction if ileus is present. Since surgery may be required, transfer to a definitive surgical facility should be considered. ANTIBIOTIC REGIMEN: (Center for Disease Control, 1998) Doxycycline 100 mg PO or IV every 12 hours, PLUS either: Cefoxitin, 2.0 gm IV every 6 hours, OR Cefotetan, 2.0 gm IV every 12 hours This is continued for at least 48 hours after clinical improvement. The Doxycycline is continued orally for 10-14 days. ALTERNATIVE ANTIBIOTIC REGIMEN: (Center for Disease Control, 1998) Clindamycin 900 mg IV every 8 hours, PLUS Gentamicin, 2.0 mg/kg IV or IM, followed by 1.5 mg/kg IV or IM, every 8 hours This is continued for at least 48 hours after clinical improvement. After IV therapy is completed, Doxycycline 100 mg PO BID is given orally for 10-14 days. Clindamycin 450 mg PO daily may also be used for this purpose. ANOTHER ALTERNATIVE ANTIBIOTIC REGIMEN: (Center for Disease Control, 1998) Ofloxacin 400 mg IV every 12 hours, PLUS Metronidazole 500 mg IV every 8 hours, ANOTHER ALTERNATIVE ANTIBIOTIC REGIMEN: (Center for Disease Control, 1998) Ampicillin/Sulbactam 3 g IV every 6 hours, PLUS Doxycycline 100 mg IV or orally every 12 hours. ANOTHER ALTERNATIVE ANTIBIOTIC REGIMEN: (Center for Disease Control, 1998) Ciprofloxacin 200 mg IV every 12 hours, PLUS Doxycycline 100 mg IV or orally every 12 hours, PLUS Metronidazole 500 mg IV every 8 hours. Endometriosis A condition in which fragments of the lining of the uterus are found outside the uterus but within the abdomen. Each month, with menses, these fragments bleed into the abdomen causing pelvic/abdominal pain, scarring, and sometimes infertility. The classical patient with endometriosis complains of about 6 months of steadily worsening dysmenorrhea, deep dyspareunia, and sometimes painful bowel movements. The physical exam will reveal the adnexal areas and cul-du-sac to be vaguely tender, without masses. When a rectal exam is done and the cervix stretched upward, tender nodules can be felt along the utero-sacral ligaments. Many medical/surgical treatments are effective. A simple but expedient therapy is taking a low-dose, monophasic BCP each day, without stopping for a menstrual flow. This approach is safe and will postpone menses for months. For cases of mild to moderate endometriosis, this approach is probably as effective as some of the more exotic medications or conservative surgery. In more severe cases, such medications as Lupron or Danazol, with or without surgery, can provide additional relief. Make sure PID has been ruled out since it can mimic endometriosis. Appendicitis This condition is characterized by progressive right lower quadrant pain. Nausea and anorexia occur early. Vague pain begins in the periumbilical area and migrates over several hours to McBurney's Point in the right lower quadrant. The patient lies supine with the right hip flexed. On examination, marked tenderness at McBurney's Point, voluntary guarding, rigidity and rebound tenderness are found. Fever is not common unless appendix is ruptured. Bowel sounds are quiet and no bowel movement will have occurred since the onset of the pain. Motion of the uterus or right adnexa causes marked pain. X-ray of the abdomen may show an oval, calcified fecalith up to 1-2 cm in diameter in the right lower quadrant of the abdomen. A sentinel loop of gas-filled small bowel next to the appendix may be seen. The treatment is essentially surgical. Antibiotics may be helpful but are not a substitute for surgery in other than extreme circumstances. If antibiotics alone are used, many patients will live but others will not. Begin treatment with intravenous antibiotics while arranging for transfer to a surgical facility for appendectomy: Unasyn 3.0 grams IV every 6 hours PLUS Flagyl 500mg IV every 6 hours, OR Mefoxin 2 gm IV every 6 hours, PLUS Gentamicin 80 mg IV every 8 hours, OR Gentamicin 80 mg IV every 8 hours, PLUS Flagyl (Metronidazole): Loading dose: 15 mg /kg infused IV over 1 hour (1 gm or 1,000 mg for a 70 kg adult) Maintenance dose: 7.5 mg/kg infused IV over 1 hour, every 6 hours (500 mg for a 70 kg adult) Bowel Obstruction A condition in which a portion of the large or small intestine becomes obstructed. Patients with bowel obstruction complain of pain, which may be cramping or constant. Abdominal dissension is prominent and patients are constipated. Nausea and vomiting usually accompany this problem. Plain x-rays of the abdomen show a distended, gas-filled loop of intestine proximal to the obstruction. If the problem is not resolved, gangrene and peritonitis develop. Initial treatment consists of decompression from above with NG suction and support with IV fluids. Partial obstructions are usually relieved with these simple measures. Complete bowel obstruction requires surgery and bowel resection. Without surgery, a complete bowel obstruction would be expected to be fatal. If surgical therapy is unavailable, IV antibiotics should be started while arranging for prompt Medical Evacuation. Degenerating Fibroid When a fibroid tumor of the uterus (leiomyoma) has metabolic needs which exceed its' blood supply, degeneration occurs. These benign uterine muscle tumors are common (40% of all women by age 40), and generally without symptoms. Occasionally, they cause trouble through excessive bleeding or pain. With degeneration, they become very tender to palpation, but the adnexal structures (tubes and ovaries) are not tender (as they would be with PID). Treatment is supportive. (bedrest, oral analgesia) Symptoms gradually resolve over 3 weeks. Definitive therapy consists of surgical removal although this is usually unnecessary. Infected/Rejected IUD Sooner or later, as many as 5% of all intrauterine devices will become infected. Patients with this problem usually notice mild lower abdominal pain, perhaps a fever and deep dyspareunia. The uterus is tender to touch and one or both adnexa may also be tender. Treatment consists of removal of the IUD and broad-spectrum antibiotics. If the symptoms are mild and the fever low-grade, oral antibiotics (ampicillin, cephalosporins, tetracycline, etc.) are very suitable. If the patient's fever is high, the symptoms significant or she appears quite ill, IV antibiotics are a better choice (cefoxitin, or metronidazole plus gentamicin, or clindamycin plus gentamicin). If an IUD is present and the patient is complaining of any type of pelvic symptom, it is wisest to remove the IUD, give antibiotics, and then worry about other possible causes for the patient's symptoms. IUDs can also be rejected without infection. Such patients complain of pelvic pain and possibly bleeding. On pelvic exam, the IUD is seen protruding from the cervix. It should be grasped with an instrument and gently removed. It cannot be saved and should not be pushed back inside. Cystitis These bladder infections are quite common. The patient complains of the classical symptoms of urinary frequency, urgency, burning on urination, and pain on completion of urination. Blood, if present, denotes "hemorrhagic cystitis." A tender bladder is virtually diagnostic, although endometriosis can also cause such tenderness. Treatment consists of: Pushing fluids, particularly acid-containing liquids such as cranberry juice or any citric juice (orange, lemon, and grapefruit). Acidity inhibits bacterial growth. Vitamin C (Ascorbic acid) can also be used to acidify the urine. Any oral broad-spectrum antibiotic, such as: Bactrim or Septra Cephalosporin Amoxicillin Tetracycline Pyridium for a day will provide immediate relief by anesthetizing the bladder mucosa. Pyelonephritis A kidney infection. These infections are characterized by CVA pain (flank pain) or tenderness, chills, fever, lassitude, and sometimes nausea and vomiting. They may be preceded by cystitis or may come without warning. Treatment is vigorous antibiotic therapy (frequently IV antibiotics because of the seriousness of the illness) and brisk fluid intake (IV or PO). Severe cases may result in septic shock, DIC and death, even with antibiotic therapy. Because of the seriousness of this condition, medical evacuation from isolated military settings is usually undertaken. If medical evacuation is not an available option, the prognosis is still reasonably good as the serious complications of pyelonephritis are not common Problems with Urination Painful Urination Painful urination is one of the classical symptoms of bladder infection, along with frequency, urgency and sometimes hematuria. Such an infection can be confirmed by a positive urine culture (>100,000 colonies/ml), or strongly supported by a positive "dipstick" (for bacteria or leukocyte esterase) and a clinically tender bladder (normally the bladder is not the least bit tender). Bladder infections are treated with broad-spectrum oral antibiotics (Gantrisin, Bactrim DS, ampicillin, Keflex, Macrodantin, etc.). Immediate relief of symptoms will occur with Pyridium 200 mg PO TID for 2 days. In operational settings, cystitis is often treated on the basis of symptoms and without confirming with cultures or dipsticks. A woman complaining of urgency, frequency and dysuria very likely has cystitis. With only limited resources, the main goal is to quickly treat any possible UTI's, return the patient to full duty, and avoid the much more serious problem of pyelonephritis. Should symptoms persists despite a course of broad spectrum antibiotics, a careful examination should be made and further testing is appropriate. Bladder infections among women in operational settings are common: Because of the difficulty in urinating (undressing in field environments, limited sanitation, etc.), many women will intentionally dehydrate, simply to avoid having to urinate. When successful, this dehydration leads to urinary stasis, predisposing them toward bladder infection. To further avoid urinating in field settings, many women will try to hold their urine as long as possible. This, too, leads to urinary stasis and predisposes towards UTIs. Gonorrheal Urethritis Urinary frequency and burning in a patient with a history of exposure to gonorrhea suggests gonorrheal urethritis. The urethra is normally not tender. Should the urethra be tender, particularly if combined with a purulent discharge, urethritis should be suspected. Paraurethral abscesses (infected Skene's glands), and eversion of urethral epithelium are often found. Gram-negative intracellular diplococci on Gram Stain or positive culture on Thayer-Martin media (chocolate agar) confirms this diagnosis. Should the operational environment disallow this precise workup, treatment is often provided on the basis of clinical suspicion and symptoms, or after a failed course of broad-spectrum antibiotics provided for a suspected UTI. Treatment is: Cefixime 400 mg orally in a single dose, OR Ceftriaxone 125 mg IM in a single dose, OR Ciprofloxacin 500 mg orally in a single dose, OR Ofloxacin 400 mg orally in a single dose, PLUS Azithromycin 1 g orally in a single dose, OR Doxycycline 100 mg orally twice a day for 7 days. Sexual partners also need to be treated. Skene's abscesses should have I&D followed by daily packing with iodoform gauze for 2-4 days. Non-gonorrheal Urethritis These patients complain of symptoms suggesting cystitis (frequency, burning, and urgency), but the urine culture is negative and they do not improve on conventional antibiotic therapy. A purulent discharge from the urethra may or may not be present, but the urethra is tender to touch. Cultures from the urethra may be positive for chlamydia, Mycoplasma or Ureaplasma, but will be negative for gonorrhea. Treatment may be started on the basis of clinical suspicion alone. Treatment is: Azithromycin 1 g orally in a single dose, OR Doxycycline 100 mg orally twice a day for 7 days, OR Erythromycin base 500 mg orally four times a day for 7 days, OR Erythromycin ethylsuccinate 800 mg orally four times a day for 7 days, OR Ofloxacin 300 mg twice a day for 7 days, OR Erythromycin base 250 mg orally four times a day for 14 days, OR Erythromycin ethylsuccinate 400 mg orally four times a day for 14 days. Herpes Painful urination in which the vulva burns when the urine drips across it can the primary symptom of herpes. In this case, inspecting the vulva will reveal multiple, small (1-2 mm), tender ulcers filled with grayish material and perhaps some blisters that have not yet ruptured. Sometimes, the pain is so intense that urination becomes complete misery. A Foley catheter until the symptoms resolve is merciful. Preferred treatment (CDC) for an initial outbreak is: Acyclovir 400 mg orally three times a day for 7-10 days, OR Acyclovir 200 mg orally five times a day for 7-10 days, OR Famciclovir 250 mg orally three times a day for 7-10 days, OR Valacyclovir 1 g orally twice a day for 7-10 days. Yeast, Trichomonas Pain on the vulva when urine passes over it can also be a symptom of yeast and less-commonly trichomonads. These infections should be apparent on inspection of the vulva/vagina and may be confirmed by microscopic examination of vaginal discharge. Painful urination may also be a symptom of other gynecologic disease, not specifically related to the bladder. Endometriosis, for example, may initially present as painful urination with a tender bladder which does not respond to typical antibiotic therapy and all urine cultures will be negative. Urinary Frequency The overwhelming number of patients complaining of urinary frequency will have one of the following problems: Bladder infection (accompanied by dysuria). Excessive fluid intake (particularly just before bedtime). Increased stress. Some pelvic mass which is pressing on the bladder Evaluation of urinary frequency involves asking the patient about her fluid intake habits and recent exposure to stress. A physical exam determines the presence or absence of: Bladder tenderness (suggesting cystitis or endometriosis) Pelvic mass (suggesting ovarian cyst, pregnancy, or fibroids) In situations where the diagnosis is unclear, a urine culture or urine "dipstick" for bacteria, nitrates or leukocyte esterase may be helpful in identifying infection. A pregnancy test is sometimes enlightening. Whenever infection is suggested, a course of oral broad-spectrum antibiotics is advised. If no infection is apparent and the patient acknowledges large fluid intake, reducing the intake some may be helpful. (don't over-react to this...too little fluid intake can be a problem also.) Blood in the Urine There is a wealth of reasons for grossly visible blood in the urine. In women of child-bearing age, not postpartum and not menstruating, the most frequent is cystitis or a bladder infection. Urinary frequency and painful urination usually accompany such an infection. The bladder is tender to palpation and urine culture will be positive (>100,000 colonies/ml). Urine "dipstick" will be positive for bacteria, nitrates and leukocyte esterase in the typical case. Treatment involves an oral broad-spectrum antibiotic (Gantrisin, Bactrim, ampicillin, Keflex, Macrodantin, etc.). If all symptoms resolve and the hematuria does not return, no further evaluation is necessary. If the hematuria does not disappear or if the patient has repeated episodes of hematuria, then urologic consultation will be necessary to look for other causes of hematuria (renal stones, bladder polyps, bladder cancer, endometriosis, etc.) Bad Urinary Odor This is usually a symptom of either a urinary tract infection (cystitis) or a vaginal infection. Examining the patient to determine the presence or absence of Gardnerella, trichomonads, yeast, or a lost tampon may be helpful in excluding vaginal problems. A urine culture or urine "dipstick" for bacteria, nitrates or leukocyte esterase may be helpful in eliminating a bladder infection as the cause of the problem. Certain foods are associated with an unusual odor in the urine (asparagus), as are certain antibiotics (ampicillin). Cannot Urinate If the patient cannot urinate at all, she will be in extreme distress with a distended, tender bladder. Insert a Foley catheter and allow the urine to begin draining. After the first 500 cc of urine has drained, clamp the Foley to temporarily stop draining for 5-10 minutes before allowing another 500 cc to drain. Continue to drain the urine in 500 cc increments until empty. Severe bladder cramps may occur if the entire bladder is drained at one time of a large amount (>1000 cc) of urine. (Severe bladder cramps may occur anyway.) After the bladder is drained, leave the Foley catheter in place for a day or two to allow the bladder's muscular wall to regain its' normal tone. Try to determine why the patient couldn't void. She may have recent trauma to the perineum or vagina which caused swelling in the area of the bladder or urethra, obstructing flow. She may have a pelvic mass (ovarian cyst, uterine fibroids, pregnancy, etc.) which has distorted the anatomy and functionally blocked the urethra. She may have herpes and cannot urinate because of the severe pain which is caused by urine flowing over open ulcers. Bladder Training After a day or two, remove the Foley catheter. Usually the patient will be able to urinate normally again. If there is any doubt, catheterize her for "residual volumes."(RV) After she urinates, insert a catheter to completely empty the bladder. If the RV is less than 50 cc, no further catheterization is necessary. If the RV is greater than 50 cc, continue to catheterize her after each urination until the RV is less than 50 cc. If the RV is quite large (>300 cc), then the bladder has probably not regained its normal tone and you should simply leave the Foley catheter in place for a few more days. Involuntary Loss of Urine There are four primary forms of urinary incontinence: 1) Loss of urine when coughing, sneezing or straining ("stress urinary incontinence"). 2) Sudden, involuntary loss of urine accompanied by urgency (unstable bladder, irritable bladder, and detrusor dyssynergia). 3) Involuntary loss of urine upon rising or standing. 4) Involuntary loss of urine at unpredictable times, not associated with urgency, frequency or other activities. Stress Incontinence Loss of urine when straining (stress urinary incontinence) affects nearly all women at some time in their life. If a woman's bladder is full enough and she strains hard enough, some urine will escape, due to the shortness of her urethra, the fragility of the normal continence mechanism, and its vulnerability to trauma during intercourse and childbirth. Genuine stress incontinence which occurs more or less daily and requires the patient to wear a pad to avoid soiling her clothing will require gynecologic or urologic consultation and usually surgery to repair the anatomic defect. Lesser degrees of stress incontinence can be treated by: Kegel exercises (periodic tightening of the muscles of the pelvic floor 10-15 times a day for 4 weeks). Frequent emptying of the bladder and "double voiding" (re-emptying the bladder 10-15 minutes after the initial void) to keep the bladder as empty as possible. Elimination of caffeine, alcohol and tobacco (common bladder irritants) which may aggravate the incontinence. A course of oral antibiotics to eliminate the chance that a sub-clinical cystitis is aggravating the incontinence. Irritable Bladder Women with an "irritable bladder" will complain that when they suddenly get the urge to urinate, they must find a bathroom within 1-2 minutes or else they will actually lose urine involuntarily. Evaluation of the irritable bladder will require gynecologic consultation, but a number of simple things can be done to relieve the symptoms while awaiting consultation. Eliminating caffeine, alcohol, and tobacco from the diet will reduce the stimulation of the bladder wall. "Double voiding" (emptying the bladder, waiting 10-15 minutes and then emptying the bladder again) will help fully empty the bladder and will reduce the stimulus. A course of oral antibiotic may eliminate any subclinical infection. Urethral Diverticulum Involuntary loss of urine upon standing or arising suggests the presence of a urethral diverticulum. This outpouching of the urethra collects and holds urine, releasing it at unpredictable times. Specialized instruments are needed to visualize most urethral diverticula and patients with this type of complaint should be evaluated through a gynecology or urology consultation. Nothing short of surgery is likely to help this particular problem. Unpredictable Urine Loss Unpredictable loss of urine not associated with urgency or activity suggests a neurologic cause. Such conditions as multiple sclerosis, spinal cord tumors, spinal disk compression and other neurologic problems should be considered. If a patient has a single episode of this type of urine loss, she can simply be reassured, but if she notes an on-going or worsening problem with this type of urine loss, careful neurologic evaluation should be performed. Urinary Urgency There are three primary reasons for urinary urgency: 1) Cystitis (bladder infection) 2) Irritable bladder (unstable bladder, detrusor dyssynergia) 3) Stress In women of child-bearing age, cystitis is the most frequent cause of this distressing symptom in which a patient suddenly has a powerful urge to urinate. Urinary frequency and painful urination usually accompany bladder infection. The bladder is tender to palpation and urine culture is positive (>100,000 colonies/ml). Urine "dipstick" will be positive for bacteria, nitrates and leukocyte esterase in the typical case. Treatment involves an oral broad-spectrum antibiotic (Gantrisin, Bactrim, ampicillin, Keflex, Macrodantin, etc.). If all symptoms resolve, no further evaluation is necessary. Persistent symptoms will usually necessitate a gynecologic or urologic consultation. Women with an "irritable bladder" will complain that when they suddenly get the urge to urinate, they must find a bathroom within 1-2 minutes or else they will actually lose urine involuntarily. Evaluation of the irritable bladder will require gynecologic consultation, as described above. Stress Stress is commonly encountered in military settings. While the stressor cannot always be reduced, the body's reaction to the stressor can, sometimes, be modified. Women who suffer from stress-induced urgency may benefit from counseling and stress-reduction techniques. Pyelonephritis A kidney infection. These infections are characterized by CVA pain or tenderness, chills, fever, lassitude, and sometimes nausea and vomiting. They may be preceded by cystitis or may come without warning. Treatment is vigorous antibiotic therapy (frequently IV antibiotics because of the seriousness of the illness) and brisk fluid intake (IV or PO). Breast Problems Breast Development At puberty, the female breast develops, under the influence of estrogen, progesterone, growth hormone, prolactin, insulin and probably thyroid hormone, parathyroid hormone and cortisol. This complex process typically begins between ages 8 to 14 and spans about 4 years. The breast contains mostly fat tissue, connective tissue, and glands that following pregnancy, will produce milk. The milk is collected in the ducts and transported to 15-25 openings through the nipple. During the menstrual cycle, the breast is smallest on days 4-7, and then begins to enlarge, under the influence of estrogen and later progesterone and prolactin. Maximum breast size occurs just prior to the onset of menses. The breast is not round, but has a "tail" of breast tissue extending up into the axilla (or armpit). This is clinically significant because abnormalities can arise there just as they can in other areas of the breast. During breast examinations, this area should be palpated. The breast is divided into quadrants to better describe and compare clinical findings. The upper outer quadrant is the area of greatest mass of breast tissue. It is also the area in which about half of all breast cancers will develop. Breast Examination A breast examination consists of inspection and palpation of the breasts to identify abnormalities. Some breast examinations are focused on specific issues while others are more general. Although there are many goodways to examine the breasts, one of them will be presented here. With the patient in a sitting position, inspect the breasts visually. While inspecting, look for: Visible masses (change in contour) Skin dimpling Nipple retraction Redness While generally symmetrical, many breasts are somewhat asymmetrical in respect to size, shape, orientation, and position on the chest wall. Have her raise her arms while you continue to watch. An underlying malignancy can fix the skin in place. Raising the arms will accentuate these changes. Flex the pectoralis major muscles. A simple way to do this is have her place her hands on her hips and squeeze inward. With flexion of the underlying muscle, areas of breast tissue that are fixed in place will move with the muscle, while the rest of the breast will not. With the patient's arm raised over her head, palpate for lumps, masses or thickenings. Breast tissue is normally somewhat nodular or "lumpy," particularly in the upper outer quadrant  Use this portion of your hand to feel for lumps. The palm of the hand is too insensitive to detect subtle changes in breast texture. The fingertips are too sensitive and will focus on the normal granularity of the breast tissue rather than the more worrisome masses. Move your hand in a circular motion while pressing into the breast substance. Making these small circles will help you identify mass occupying lesions. With smaller breasts, palpation with one hand will give good results. When breasts are larger or pendulous, it may be useful to use two hands, compressing the breast tissue between them. Check the axilla for masses or palpable lymph nodes. The supraclavicular area can be an area of spread of breast malignancy. Check for any palpable masses or lymph nodes in this area. Then have the patient recline. Sometimes, lumps or masses are better appreciated in the reclining or semi-reclining position. One or two hands can be effectively used. The axilla can be checked in the reclining position or semi-reclining position. The supraclavicular area can also be examined in the reclining or semi-reclining position.  Stripping the ducts toward the nipple will cause any secretions to be expressed. Self Breast Exam Self breast exam comprises one portion of the triad of early detection of breast abnormalities, the other two being professional breast exams and screening mammography. This is appropriate, as the woman herself first discovers most breast abnormalities. Once a month, just after completing a menstrual flow, a woman should examine her breasts. This can be done in the shower, but at least part of the exam should be done while standing in front of a mirror. Inspect the breasts for: Skin changes Redness Visible bumps Nipple crusting Symmetry When raising her arms up, both breasts should rise evenly on the chest wall. While raising her arms, she should watch closely for any skin dimpling or nipple retraction. With her arm raised, she should feel for lumps with the opposite hand. Most breast tissue is somewhat nodular. She is feeling for a "marble in a bag of rice." She should move her hand in small circles while compressing the breast tissue. Then she should move to another area and perform the same small circular examination.  Many people find it easiest to move in a clockwise fashion to avoid missing any areas of the breast. The same circular motion should be used to exam the armpit and the "tail" of the breast that extends up into the armpit. In the armpit, she is feeling for any breast lumps or lymph nodes. Enlarged lymph nodes are about the size of a pencil eraser, but longer and thinner. She should try to express nipple discharge by stripping the ducts towards the nipple. Normally, there will be one or two drops of clear, milky or green-tinged secretions. Mammography Mammography is most often used as a screening technique for breast cancer. Breast examinations detect most cancer, but will miss some, particular the very early cancers that are too small to feel. Mammograms are good at detecting some of these early cancers, but will miss others. This means that breast exams and mammograms are complementary, each detecting problems the other might miss. Mammography looks for radio-opaque densities, microcalcifications, and disruption of the normal breast architecture (parenchymal asymmetry). For women without strong risk factors for breast cancer, screening mammography is often done every other year between ages 40 and 50, and then annually after age 50. Ultrasound Mammography is very good at detecting radio-opaque changes, such as calcifications or architectural distortion from a mass effect. Ultrasound, in contrast, is very good at distinguishing cystic from solid masses. This is probably most useful following mammographic findings of a benign-appearing, non-palpable density, although it can also be used with palpable masses. Breast Biopsy Suspicious dominant breast masses are biopsied, as are suspicious areas found on mammogram. Commonly, this is done by fine-needle aspiration (FNA). A very thin needle is placed in the suspicious area, suction applied, and multiple, tiny core samples taken. Alternatively, open biopsy is sometimes necessary to remove all the suspicious tissue. Supernumerary Breasts Supernumerary breasts are relatively common. They are found along the "milk line," extending from the axilla to the groin. Most of them are not noticed clinically until pregnancy occurs. Then, under the influence of the pregnancy hormones, the breasts enlarge in preparation for lactation. It is at this time that soft swellings along the milk line occur, representing supernumerary breasts. During lactation, the extra breasts may produce milk. The two most common places for them are in the axilla and directly underneath the normal breast. These are not dangerous and are generally ignored. If they prove to be a cosmetic problem, they can be removed surgically. Supernumerary Nipples With stimulation and nipple erection, most inverted nipples will evert. Occasionally, they remain inverted despite all efforts to evert them. Other than for cosmetics, nipple inversion is not usually a problem. For breast-feeding, most inverted nipples will evert. Even those that do not evert may still function normally enough to allow for satisfactory infant nursing. More common than supernumerary breasts are supernumerary nipples. Like extra breasts, these are located in the milk line and are not dangerous. Unless they are large, they are usually not noticed until a pregnancy. At that time, like the normal nipples, they enlarge and darken. Inverted Nipples Usually nipples point outward. Sometimes, they invert. When they persistently point inwards, they are called inverted nipples. This can be unilateral or bilateral. Adolescent Breast Problems There is considerable individual variation in age at which this development occurs. Asymmetrical breast growth during adolescence is the rule rather than the exception. Reassurance is given that the asymmetry usually evens out by the time of full maturation. Mammary hypertrophy can be a distressing symptom. Because growth and development continues for a long time, surgical intervention, if contemplated is postponed until the breasts are fully mature. Breast masses in adolescents are essentially 100% benign. Because of this, surgery (excisional biopsy or fine needle aspiration) is almost never warranted. Further, the surgical disruption of architecture can be disfiguring as the breast continues to mature. Pregnancy Changes During pregnancy, a number of changes occur over time which prepare the breast for lactation: Early in the first trimester, the breasts and nipples become tender. The tenderness persists until the end of the 1st trimester, at which time the tenderness disappears. By the end of the first trimester, enlargement of the breast and nipple is noticeable. By the third trimester, the breast and nipple have experienced further enlargement and the Montgomery's glands around the periphery of the areola become more pronounced. The nipples gradually darken, becoming dark brown or black by full term. Puerperal Mastitis During lactation, breast infections (mastitis) are common. They are usually caused by common skin bacteria (particularly staphylococcus) being introduced into the ductal system through cracked nipples and the inoculation by the newborn suckling. Clinically, these patients present with a rapid onset of unilateral breast tenderness, redness, fever, and sometimes a thickening or mass. Breast infections can be very aggressive with high fevers developing quickly. Immediate treatment is important to keep an otherwise simple mastitis from developing an abscess, requiring surgical drainage. Good treatments include: Dicloxacillin 250 mg PO QID x 7 days Oxacillin 250 mg PO QID x 7 days Erythromycin 250 mg PO QID x 7 days Azithromycin 1 gm, 2 PO, then 1 PO QD Continue to breast feed from the affected breast as drainage is important. Recurrent infections are common. Nipple Laceration Occasionally, with vigorous nursing or newborn biting, a nipple laceration will occur. This requires careful attention to avoid a major wound infection or breast abscess. The nipple should be kept very clean and breast feeding on that side stopped to allow the nipple to completely heal. Instruct the patient to watch for any increasing tenderness or redness, which may be evidence of a developing infection. Routine administration of antibiotics are generally not necessary unless the laceration is already infected or grossly contaminated. Cyclic Breast Pain During the days leading up to the menstrual flow, the breasts normally are somewhat engorged and may be somewhat tender. Following the onset of menstrual flow, these changes spontaneously resolve. If the tenderness is more than mild or is clinically bothersome, it is called cyclic breast pain or mastodynia. If examined during this time, these women also often have significantly enhanced nodularity of the breast tissue. the combination of cyclic breast pain and symmetrically thickened nodularity of the breast tissue is often called fibrocystic disease (misnamed because it's not really a disease) or fibrocystic breast changes. While not dangerous, women with cyclic mastodynia find it annoying and in its most severe form, interferes with some normal activities. Some women find that by reducing or eliminating their intake of caffeine (coffee, tea, cola drinks) and taking Vitamin E supplements (400 IU daily) has seemed to improve their symptoms. Whether such improvement is pharmacologic or placebo in nature is still under debate. Any pharmacologic approach that suppresses ovulation will be very helpful in treating cyclic mastodynia. Among these, birth control pills are the simplest. Taking BCPs in the usual fashion generally improves the pain significantly. For those who still experience significant pain, continuous birth control pills will usually suppress the pain completely. Also effective, by virtue of ovulation inhibition, are depot medroxyprogesterone acetate, Lupron, or Danocrine, the latter two usually justified only in severe cases due to their significant side effects. Non-cyclic Breast Pain Among the common causes of non-cyclic breast pain are trauma, infection, and chest wall pain underlying the breast tissue (muscle strain or overuse of the pectoralis major muscle). Breast cancer rarely causes breast pain in the early stages and is not usually suspected unless the symptoms persist. Hormonal causes include functional ovarian cysts and pregnancy. Women complaining of non-cyclic breast pain should have a careful examination and if the pain persists, referral will likely be necessary. Nipple Discharge Normally, if the ducts are stripped toward the nipple, a drop or two of clear, milky, or greenish-tinged liquid will appear. This is not considered nipple discharge. If the nipples spontaneously leak discharge, staining the clothing, that is not normal, nor is it normal to have bloody nipple secretions. Nipple discharge from both breasts indicates "galactorrhea." While a few post partum women will continue to leak small amounts of milk for years following delivery, galactorrhea in general indicates the need for a serum prolactin measurement and possibly an MRI of the pituitary gland to look for prolactin-secreting pituitary adenomas. Hypothyroidism can also cause this problem, although it is rare. Athletes may experience small amounts of galactorrhea from constant rubbing of the nipples against clothing. Frequent sexual stimulation of the breasts may have similar effects. The serum prolactin measurement is best made after a few days of non-stimulation of the breast. Even after a breast exam, it is often helpful to wait 2 days before measuring the serum prolactin. Persistent discharge from a single duct, particularly if bloody, rust-colored or multicolored, suggests the presence of an intraductal lesion, such as a papilloma. While these are often benign, they need further exploration with a general or breast surgeon. Fat Necrosis Fat necrosis presents as a breast mass with surrounding ecchymosis (bruise). It may be tender and a history of breast trauma is identified in half the cases. Even when significant trauma is not identified, it is felt to be the general cause of this condition. This benign condition is self-resolving, but is of clinical importance because it mimics the dominant mass found in breast cancer. Those cases with the typical presentation can be followed to make sure they completely resolve. Those cases that are not typical or if there is any doubt, can have a fine needle aspiration to confirm the diagnosis. Paget's Disease This crusty, flaking lesion is associated with an underlying breast malignancy, invasive or in-situ. The appearance may be suggestive of Paget's disease, but the diagnosis is generally confirmed by nipple biopsy. The onset of the lesion is often so gradual that by the time it comes to the attention of the physician, many months or years have passed since its' onset. Treatment depends on the character and extent of the underlying lesion. Breast Mass If a dominant mass is found in the breast which persists through the menstrual cycle, it is usually biopsied, either through fine needle aspiration or excisional biopsy, depending on the clinical circumstances. In operational settings, this can wait a few weeks, but should not wait much longer. Suspicious masses (large, irregular, hard, fixed in place, with redness and dimpling of the overlying skin and nipple retraction) are usually biopsied right away. Most masses are benign, but for those found to be malignant, earlier intervention is thought by many to lead to improved chances of successful treatment. Breast Cyst Breast cysts present as smooth, non-tender masses. They will often disappear over the course of the menstrual cycle, but those that persist will need further evaluation.  Cyst aspiration is frequently attempted, using a small needle and syringe. After aspiration of the cyst fluid is performed primarily to confirm the fact of the cyst and to decompress it. Many physicians discard the cyst fluid unless it is bloody as cyst fluid cytologic examination is felt to be of little value. Following decompression of the cyst, the patient returns for periodic follow-up to look for recurrence. Recurrent cysts in the same location are often subjected to excisional biopsy or fine needle aspiration biopsy. Fibroadenoma These common, benign, solid, round or oval breast tumors are most common among women ages 15-35. They are rubbery in consistency, mobile and non-tender. They rarely grow larger than 2-3 cm. The diagnosis is usually suspected on physical exam and confirmed with fine needle aspiration or excisional biopsy. When found in teenagers, they are often simply watched because of the very low risk of malignancy compared to the architectural disturbance caused by excisional biopsy. Breast Cancer Breast cancer is a relatively common cancer, representing about 30% of all cancers in women. In broad terms, treatment is successful in about 3 out of 4 patients in controlling or eliminating the cancer. In about one out of four, the cancer proves fatal. The risk of developing breast cancer increases steadily with increasing age. It is rare among women under age 25 but affects nearly one in nine of those women reaching age 90. A number of factors are associated with an increased of developing breast cancer, including: Strong family history of breast cancer Menopause after age 55 No term pregnancy prior to age 35 Despite the increased risk, most (about 80%) of breast cancer occurs in women not at increased risk for developing breast cancer. For that reason, efforts at early detection are not focused just on those with somewhat increased risks, but on all women. The primary strategy involves a three-armed effort: Periodic (annual) professional breast examination, monthly self-breast examination, and mammography at appropriate intervals. Menopause Definition Menopause occurs when the ovaries stop functioning and cease producing the female hormone, estrogen. This is a natural event in the life of all women, occurring, on average, at age 51 in North America, although there is considerable variation from person to person. Among those women who undergo surgical removal of the ovaries, menopause occurs immediately. Strict definitions have sometimes included such guidelines as 1 year without a period, accompanied by hot flashes. The diagnosis of menopause is usually made on clinical grounds, but laboratory tests can be helpful in some patients. These would include a depressed serum estradiol (estrogen) level, resulting from ovarian failure. The pituitary gland, sensing the low levels of estrogen, responds by releasing steadily increasing amounts of ovary-stimulating hormones (gonadotropins), in the form of FSH (follicle stimulating hormone) and LH (luteinizing hormone). The typical laboratory profile of a menopausal woman includes markedly elevated FSH and LH, with a low estradiol level. Symptoms The classical symptom of menopause is "hot flashes," an unpleasant sensation of sudden warmth and facial flushing, followed within minutes by profuse sweating. If this occurs at night, it is called a "night sweat," and can be so dramatic as to require the woman to change her clothing for comfort following the night sweat. Other symptoms include vaginal dryness (and associated painful intercourse), sleeplessness, depression, memory loss, and decreased libido (sex drive). Not all menopausal women experience all of these symptoms. Women who do experience these symptoms may not experience them all at the same time. Associated Medical Problems Following the loss of a regular supply of estrogen, a number of medical problems can gradually arise. Perhaps the most well-known of these is "osteoporosis," a loss of calcium from the bones, resulting in weakening of the bones and ultimately a risk of serious fractures. The risk of cardiovascular disease rises after menopause. During their childbearing years, women enjoy a degree of relative protection against cardiovascular disease, in comparison to men. Following menopause, they lose this relative protection and their risk becomes similar to that of men of the same age, other risk factors being similar. Clinical Presentation Many people think that menopause is a sudden event. They believe that once it occurs, a woman is "menopausal" and ovarian function will never return. While such a presentation may occur in some women, it is not the typical way for menopause to occur. Usually, there is a period of several months to several years, during which a woman will go in and out of menopause. She will, at times, experience hot flashes and no menstrual flow for months, only to be followed by a brief resumption of ovarian function. She will feel much better and will notice that her hot flashes have gone away. She will likely believe that she is done with hot flashes, only to be surprised later when ovarian function again fails and she again experiences hot flashes. This on-again, off-again presentation can be troublesome, both for the woman and her health care provider. During the episodes of hot flashes, laboratory tests for menopause (an elevated LH and FSH with a low estradiol level) will generally confirm the diagnosis. However, if repeated after the hot flashes have gone away and menstrual function has resumed, they will return to normal levels. Philosophy of Management One view of menopause is that it is a perfectly natural, predictable event in the life of every woman. The role of the health care provider should be to help the woman adjust to her menopausal state, using the least amount of medication for the shortest period of time, with the goal of being off of all medication. The alternative view, is that menopause represents the premature failure of an important organ, with significant medical consequences. If a woman developed diabetes (failure of the pancreas), we wouldn't try to help her learn to live without insulin...we would give her as much insulin as she required to make her normal. If a woman developed hypothyroidism, we wouldn't try to help her learn to live without thyroid hormone...we'd give her as much thyroid hormone as it would take to make her normal again. In the presence of ovarian failure, we should try to replace the hormones (estrogen primarily) which are no longer being produced by the woman' ovaries. This is done with estrogen replacement therapy (ERT). Benefits of Treatment The benefits likely to accrue to the menopausal woman taking ERT include: Substantially reduced risk of osteoporosis Reduced risk of cardiovascular disease Improved memory Reduction or elimination of hot flashes and night sweats Reduction or elimination of sleeplessness and depression Reduction or elimination of vaginal dryness Risks of Treatment The use of estrogen replacement therapy likely leads to a small but measurable increased risk of gallstones. The use of estrogen alone, without balancing with progesterone, carries an increased risk of the development of endometrial hyperplasia and cancer of the uterus. If progesterone is used with the estrogen, this risk of cancer is actually less than that of the untreated population. In other words, using a combination of estrogen and progesterone protects against the development of uterine cancer. More controversial is whether ERT increases the risk of breast cancer. Because of the limitations of the many scientific studies which have studied this issue, we really don't yet know whether ERT increases the risk of breast cancer, reduces the risk of breast cancer, or has no effect on the risk of breast cancer. It is probable that if ERT has any effect on the risk of breast cancer, it is a very small effect, not a large effect. If it had a big effect, that effect would have been obvious by now to most scientists looking at the issue. Similarly controversial is whether women with a prior history of breast cancer should take estrogen. Strong feelings on both sides of the issue are plentiful. There is scientific merit to both sides, and this controversy is not likely to be resolved any time soon. Alternatives Regular, weight-bearing exercise, is known to have a beneficial effect on slowing the loss of calcium from the bones. The effect is small (much smaller than that of estrogen). Exercise also has beneficial effects on mood changes, libido, and reducing cardiovascular disease. Exercise generally has no effect on hot flashes, night sweats, or vaginal dryness. Increased calcium intake has a beneficial effect on osteoporosis, but like exercise, the effect is very small, much smaller than the effect of estrogen. Typical recommendations for calcium intake are 1200 to 1500 mg per day of elemental calcium. This can be in the form of calcium tablets, but many antacid tablets contain similar amounts of calcium and may be less expensive for the patient. In theory, eating calcium-rich foods could also meet this need, but most people find it difficult to consistently eat enough calcium-rich foods to meet this requirement. Several other medications may be useful during menopause. Often called "SERM's" (selective estrogen receptor modulators), they act in some respects like estrogen and in other respects, they do not. One of the most well-known of these, Fosamax is highly effective at blocking the loss of calcium from the bones, and can rebuild bone. It has no other apparent estrogenic effects. While this makes for few side-effects, it will not relieve hot flashes, night sweats, or the mood changes which often accompany menopause. Nor will it protect against cardiovascular disease. Several other non-hormonal medications, such as Bellergal-S, and Peridin-C have been used to treat menopausal symptoms. These reportedly act by stabilizing smooth muscle, blocking the vasodilatation associated with hot flashes. Bellergal-S also contains a mild hypnotic, which may promote sleep at night. Some women may obtain symptomatic relief with these medications while others will not. They do not provide any protection against osteoporosis or cardiovascular disease. Standard Treatment Usual treatment consists of a combination of estrogen and progesterone. This may be taken either continuously, without letup, or in a cyclical fashion. There are different doses of both estrogen and progesterone. Conjugated estrogens, for example, are usually used in a 0.625 mg pill, but also come in a smaller (0.3 mg) and larger (0.9, 1.25, 2.5 mg) pill. Start with a standard dose of estrogen (0.625 mg) and then you may adjust the dose higher (if she continues to experience hot flashes), or lower (if she experiences significant, persistent estrogen side-effects). If laboratory facilities are available, a good target range for serum estradiol levels among menopausal women on ERT would be about 50-100. Progesterone also comes in different doses. If progesterone is to be taken continuously, a dose of 2.5 mg per day is generally sufficient to protect against endometrial hyperplasia. If taken for shorter periods of time (cyclic therapy), then the dose needs to be higher to achieve a similar effect on the uterus. If taken 10 days per month (the shortest recommended time) then a full 10 mg each day is indicated. Continuous treatment often consists of: Conjugated estrogens 0.626 mg orally each day, PLUS Medroxyprogesterone acetate 2.5 mg orally each day. OR Estradiol 1 mg orally each day, PLUS Medroxyprogesterone acetate 2.5 mg orally each day. About 80% of women taking continuous ERT in this way will have no bleeding at all. The 20% who do have some bleeding will need careful gynecologic follow-up (assessment of the endometrium) to rule out significant pathology as an underlying cause of the bleeding. Eventually, most of this bleeding will stop, but there will still be some women who continue to have irregular bleeding on this regimen. They are usually moved to the cyclic form of ERT so that the bleeding will at least be predictable. Cyclic treatment often consists of: Conjugated estrogens 0.626 mg orally for the first 25 days of each calendar month, PLUS Medroxyprogesterone acetate 10 mg orally on days 16-25 of each calendar month. OR Conjugated estrogens 0.625 mg orally, days 1-25 of each month, PLUS Medroxyprogesterone acetate 5 mg orally, days 14-25 of each month With cyclic therapy, about 1/3 of the women will have monthly menstrual cycles, about 1/3 will initially have monthly menstrual cycles which will later disappear, and about 1/3 will continue to have monthly cycles no matter how long they stay on the ERT. Birth Control Pills For women in the peri-menopausal time (the few years leading up to menopause and the first few years after menopause), birth control pills are sometimes used as ERT. These are particularly useful in women who are experiencing several months of ovarian dysfunction (menopausal symptoms), followed by resumption of normal function. The back and forth instability can be annoying and lead to considerable medical intervention. For these women, starting BCPs usually relieves their menopausal symptoms and provides very normal, regular, predictable menstrual flows each month. While the BCPs are not ideally suited to long-term ERT (too much progestin), they can be safely used in this age group for a number of years until the woman is past the "peri-menopausal" time. When using BCPs for this purpose, the usual contraindications for BCPs apply. Risk of Pregnancy A common question women in the peri-menopausal state often have is when to stop using birth control methods. The answer is complicated. A woman who is truly menopausal should not need birth control. However, because of the tendency to go in and out of menopause for a while before menopause is firmly established, pregnancy remains an issue. A woman might have skipped 4 periods and had intense hot flashes before once again ovulating. If she were to have unprotected intercourse, a pregnancy could possibly occur. For this reason, traditional recommendations have been that after one year of no menstrual flow, accompanied by hot flashes, in a woman of menopausal age, contraception need not be employed. This guideline may not be very useful in the current atmosphere of aggressive medical management of menopause. Spontaneous pregnancies (without infertility treatments) after age 50 are very rare. The risk of spontaneous pregnancy after age 50 is about the same as the risk of pregnancy occurring in a 22 year old who is using condoms for contraception, and less than the risk if she were using a diaphragm. For women seeking a higher degree of protection, other contraceptive techniques may be used until age 55. Spontaneous pregnancy after age 55 is essentially nil. Libido (Sex Drive) Interest in sex (libido, sex drive) varies from individual to individual, and within the same person from time to time. Menopause has no consistent, predictable influence on sex drive. Some women may find an increase in libido, possibly related to freedom from fear of pregnancy. Others notice no change. Others may experience a lack of interest in sex. Loss of interest in sex may occur for several reasons. The emotional and psychological changes associated with menopause (depression, mood swings) may influence it. Loss of sleep due to night sweats can adversely influence sex drive. Other factors (children leaving the home, marital discord) may play a role. To the extent that ERT corrects an underlying hormonal abnormality and eliminates menopausal symptoms, this loss of libido may be corrected. Other menopausal women may experience diminished sex drive to changes in testosterone levels. Male hormone, testosterone, is normally produced in small quantities by women. About 1/3 comes from the ovaries and the rest comes from other organs in the body. As ovarian function ceases during menopause, not only do female hormones (estrogens) fall, but also male hormone levels drop. The fall in male hormone levels is not as dramatic, because they only fall by about 1/3. For some women, this drop proves to be insignificant, but for others, even this small drop can have significant effects on them. Among these effects are loss of libido. For women who experience a loss of libido, it is useful to explore the many reasons for this. It may also prove useful to give a therapeutic trial of small amounts of testosterone. One convenient product, Estratest, contains both conjugated estrogens and a small amount of methyl testosterone. It can be substituted for the usual estrogen component of ERT and the patient reassessed in a month or two to see if it will be helpful. Some women with a loss of libido are comfortable with their new circumstance and prefer no intervention. Follow-up Any women taking ERT who experience abnormal bleeding will need to be evaluated carefully for the presence of significant endometrial pathology. Various techniques used to accomplish this evaluation may include endometrial biopsy, D&C, hysteroscopy, and fluid-enhanced ultrasound. Because of the theoretical potential for estrogen to stimulate breast cancer cells, women taking ERT are very good candidates for regular mammography (annually after age 50). Likewise, annual pelvic and breast exams are indicated in these women. Some providers make good use of bone density scans to determine the relative strength of a woman's bones. These tests may indicate women who might benefit from the use of ERT but who would otherwise be disinclined to take it. The test may also be used to follow the progress of women with known osteoporosis, assisting the provider in determining the extent of therapy and its effects. It is unknown whether the benefits of ERT continue indefinitely, so any recommendation of how long a woman should take ERT is speculative. Many women take ERT through their mid-70s. Sexual Assault Outline of Management Sexual assault is any sexual act performed by one person on another person without that person's consent. This is an act of violence with medical, mental and legal issues which should to be addressed. Described below is a standard medical approach to sexual assault when resources are available and tactical circumstances allow. Should sufficient resources (personnel, equipment, and laboratory support) not be available, or the tactical situation disallows full application, these general principles can usually still be followed, although with an abbreviated application. Evaluate the patient for serious injuries (fractures, hemorrhage, etc.) which might require immediate treatment. Obtain a brief history, explaining to the patient what will occur next. Obtain patient's consent. Gather all necessary materials and notify legal and administrative authorities. Examine the patient, obtaining various specimens. Offer treatment for VD, pregnancy. Arrange for follow-up care. Assign Staff Member From the beginning of the patient's interaction with you, a staff member of the same sex and preferably similar rank should be assigned to remain with the patient for the duration of her care until she leaves the medical area. This person's responsibilities are to provide psychological support, explain procedures, and serve as a witness/chaperone. Serious injuries come first If the patient has serious injuries, take care of the injuries before worrying about collecting legal evidence. Patient care takes priority. Notify Authorities Early in this process, legal and administrative authorities need to be notified that a sexual assault has been reported and medical care is being provided. At sea, this would include both the Officer of the day (deck) and a representative from the NIS or Master-at-arms. Notify the Chaplain In many circumstances, a Chaplain serves the role of a social service provider and should be notified of this occurrence. In other circumstances, other alternatives may be more appropriate. Consent Consent should be obtained from the patient to: Examine her and provide medical treatment. Collect evidence. Taking photographs (if indicated). Release medical reports and evidence to legal authority. Should consent be withheld, notify higher authorities for a determination whether a non-consensual examination will be ordered. Gather your supplies Before you actually examine the patient and begin collecting your exam specimens, it is best to gather all the materials you will need first. This saves you time and spares the patient the unpleasantness of a prolonged examination. It also helps you avoid forgetting something. If you think you have completed your exam, but you still have some supplies left, you probably forgot about something. In many areas, "Sexual Assault Investigation Kits" are prepared in advance, containing everything needed for this examination. If a pre-packaged kit is not available, you may wish to consider making your own prior to the need for it arising. All specimens should be properly labeled and maintained by precise chain of custody. Labels Every specimen taken from the patient must be properly labeled. The label should include: Patient's name SSN Date Time Identity of specimen (e.g., "fingernail scrapings) Location (e.g., "right hand") Examiner's initials It is very helpful to make up your labels before you examine the patient. In addition to labels for all of the specimens, you will need to label lab requisitions, your medical report, and the consent forms. You will need at least 25 labels, not counting any labels used on laboratory requisitions. Materials Needed Authorization (consent) forms for examination, medical treatment, collection of specimens, release of information to proper authorities, and, if indicated, photography. Laboratory requisition forms: Pregnancy test (HCG) VDRL or RPR HIV Hepatitis B 3 gonorrhea cultures 1 chlamydia test 9 Paper envelopes 2 Combs, new and unused 1 Tongue blade 6 twin-packs of cotton-tipped applicators, sterile 1 Flashlight 5 ml of distilled or sterile water (not saline) 3 glass microscope slides with the frosted ends labeled in pencil with the patient's last name and SSN 3 Slide holders (cardboard, not plastic). If only plastic are available, use them, but don't seal the ends...use cellophane tape to partially cover the end, allowing air to circulate freely, but disallowing the glass slide to fall out. 25 Labels, with name, SSN, date, identity, location, initials 2 pieces of filter paper 2 Red-top blood tubes 2 wooden toothpicks 1 vaginal speculum 1 pair of latex examination gloves Lubricating jelly (such as KY or Surgilube) 2 pieces of plain white paper, 8.5" x 11" 3 Chocolate Agar plates 1 Chlamydia test kit Fresh clothing for the patient Mouthwash and cup Toothbrush and toothpaste Betadine douche (mix small amount of Betadine with 100 ml water and load in a 30-50 ml syringe) Emesis basin or similar small basin Camera and color negative film for taking photographs of traumatized areas, if indicated History Find out from the patient what happened. She will need to be as specific as possible about exactly what was done to her, when, where, by whom, etc. Write down her description of what happened, but remember that you are not in a position to judge whether a rape or sexual assault occurred...you are simply repeating what the patient told you. For example, you might say, "Patient states she was raped today at 4:00 pm by an unknown person in Storage Room #3." You should not say, "The patient was raped at 4:00 pm," because that implies a legal conclusion on your part. You should also not say, "The patient was allegedly raped at 4:00 pm," because this use of the word "allegedly" has been interpreted by some people to imply that you didn't believe that a rape occurred. It is better to simply condense and repeat what the patient told you. Gynecologic History Particularly important are: LMP Use of contraceptives, such as BCPs Any significant past gynecologic history Sexual history: You need not obtain a detailed sexual history, but two issues are important to explore with the patient: first, whether she has ever had sexual intercourse prior to the sexual assault, and second, the last time sexual relations occurred within 72 hours prior to the assault. Clothing If any clothing contains moist or dry stains, remove the clothing, let it dry completely, and place it in a paper bag (not plastic). Use one paper bag for each piece of clothing. Seal each bag and label it. The clothing should be given to the law enforcement authorities and signed out using a chain of custody form. Give the patient a property receipt card for her clothing Physical Exam Start at the patient's head and work downward, explaining to her what you are doing as you examine her and collect specimens. If you encounter any physical evidence of trauma, you should draw a picture of your findings and, if possible, photograph the evidence. Photographs Ask your ship or unit photographer to explain the operation of the camera to you, but you should take the photographs yourself, without the photographer being present, particularly if the trauma involves areas around the breasts or perineum. Head Combings Lightly comb the patient's hair over a plain white sheet of paper. Fold the paper over the comb and any loose hairs and place everything in an envelope. Seal and label it. Do not pluck hairs from the head to serve as controls. While obtaining plucked hairs is recommended by some law-enforcement agencies, this is a painful and humiliating experience for the patient and almost never makes any difference in the final legal outcome of the case. If the law-enforcement jurisdiction in which you are located later requires plucked hairs, they can ask for them at that time. Mouth Using two dry cotton-tipped applicators, gently obtain a specimen from each side of the gums, both right and left, top and bottom. Smear the specimen on a glass slide and let it air-dry. Place the dried glass slide in a cardboard slide holder, label it and seal it. Let the cotton swabs air-dry and then place in an envelope, label it and seal it. Use another dry cotton swab to obtain a specimen for smearing on a chocolate agar plate to test for gonorrhea. Label the plate, discard the swab and send the plate to the laboratory. Ask the patient to place one piece of filter paper in her mouth to become saturated with saliva. She should not chew the filter paper. When saturated, ask her remove it from her mouth with her own fingers and place it in an envelope. Do not touch the filter paper yourself. Let the filter paper air-dry. Then seal it. Carefully inspect the oral cavity, using a tongue blade and flashlight, noting any evidence of trauma. After examining the mouth, offer the patient a toothbrush and toothpaste and mouthwash to rinse her mouth. Particularly if oral contact was involved in the assault, she will feel much better after cleansing her mouth. This will also give her a psychological break in the exam. Torso and Arms Inspect and palpate for any evidence of trauma, lacerations, bruises, abrasions, tenderness, etc. Record any significant findings. Hands Collect fingernail scrapings using the wooden toothpicks, one for each hand. The patient may do this herself with you observing. Place the scrapings and the toothpicks in two envelopes, one for the right hand and one for the left hand. Label and seal them. Pubic Hair Combings Lightly comb the pubic hair over a plain white piece of paper. Fold the comb and any loose hairs into the paper, place in an envelope, label and seal it. There may not be any loose hairs. Do not pluck hairs from the pubic area to serve as controls. While obtaining plucked hairs is recommended by some law-enforcement agencies, this is a painful and humiliating experience for the patient and almost never makes any difference in the final legal outcome of the case. If the law-enforcement jurisdiction in which you are located later requires plucked hairs, they can ask for them at that time. Inspect the Vulva Using good light, carefully inspect the vulva for signs of trauma, lacerations, bruises, abrasions, etc. Note the status of the hymen. Application of toluidine blue dye (rinsed with vinegar) can highlight recent trauma. Metabolically active cells retain the dye. Before Toluidine Blue DyeAfter Toluidine Blue Dye Visualize the Cervix Using good light, carefully inspect the vulva for signs of trauma, lacerations, bruises, abrasions, etc. Note the status of the hymen. After moistening the vaginal speculum with warm water, insert it into the vagina and inspect the vagina and cervix for signs of trauma. Vaginal Swab Using two dry cotton-tipped applicators, swab the vaginal walls and posterior fornix (area beneath the cervix). Smear this specimen on a glass slide, allow it to air-dry and place it in a cardboard slide holder. Label and seal the slide holder. Let the cotton swabs air-dry and then place them in an envelope. Label and seal the envelope. Do not try to examine the vaginal or cervical specimens for motile sperm unless you are experienced in this technique. Forensic pathologists will examine the dried slides and their skills are considerable. You may jeopardize later legal proceedings if you inartfully look for motile sperm and reach conclusions which are different than those of the forensic pathologist. From this perspective, it is better to leave the microscopic examinations to the experts unless you have experience and training in this area. Chlamydia Culture Use your chlamydia test kit to obtain a cervical specimen. Gonorrhea Culture Use a dry cotton swab and chocolate agar plate or other suitable sampling technique to obtain a specimen from the endocervical canal. Label the plate and send it to your laboratory. Rectal Examination In the case of rectal assault, inspect carefully for tears or breaks in the skin of the rectum. Toluidine Blue dye can be helpful. An anoscope can be used to inspect the lower rectum. Use two cotton-tipped applicators, moistened with distilled water, to obtain a specimen from just inside the rectal sphincter. Smear this specimen on a glass slide, allow it to air-dry and place it in a cardboard slide holder. Label and seal the slide holder. Let the cotton swabs air-dry and then place them in an envelope. Label and seal the envelope. Use another moistened cotton-tipped applicator and a chocolate agar plate to test your patient for gonorrhea. Send this specimen to your lab. Bimanual Exam After collecting all specimens, perform a bimanual exam. Using the lubricating jelly, palpate each of the pelvic structures, noting any enlargement or tenderness. Betadine Douche Once the pelvic examination is completed, the patient will generally appreciate a cleansing douche of Betadine mixed in water. 50 to 100 cc of solution can be used to rinse the vagina, using a 30 or 50 cc syringe. Collect the rinse in the emesis basin and discard. Let the patient shower This is very important for her psychological health. Usually, there are no major physical injuries after a sexual assault, but the psychological injuries can be great. A part of your treatment will be to reassure her that she's "OK" and to assist her in the cleansing process (physical and mental). Once the specimens are collected, she should be given the opportunity to shower and change clothes, in a sense "washing away" some of the unpleasantness of her recent experience. Some women will decline, preferring to shower later, but many will appreciate the offer and will feel better afterward. Blood and Urine Tests VDRL or RPR - repeat in 1 month Hepatitis B - repeat in 1 month HIV - repeat in 1 month and 6 months Pregnancy test - repeat weekly until next menstrual flow 1 extra red-top tube for the Investigator (MAA or NIS) Place 4-5 drops of the patient's blood (taken from the needle or drawn from one of the red-top tubes) on a piece of filter paper and let it air-dry. Place the filter paper in an envelope, label it and seal it. Offer Antibiotics The risk of acquiring gonorrhea from a sexual assault is approximately 6 to 12% (CDC), and the risk of acquiring chlamydia probably a little higher. The risk of acquiring syphilis is estimated at about 3%. The risk of developing AIDS from a sexual assault cannot be precisely estimated as it depends on too many factors but is considered to be quite low. Standard prophylaxis: Ceftriaxone 125 mg IM, plus Azithromycin 1 g PO once (or Doxycycline 100 mg PO BID x 7 days), plus Metronidazole 2 g PO once Alternative prophylaxis: Spectinomycin 2 gm IM, plus Doxycycline 100 mg PO BID x 7 days During Pregnancy: Ceftriaxone or Spectinomycin, plus Erythromycin 250 mg PO QID x 7 days Postexposure hepatitis B vaccination (without HBIG) should adequately protect against HBV. Hepatitis B vaccine should be administered to victims of sexual assault at the time of the initial examination. Follow-up doses of vaccine should be administered 1-2 and 4-6 months after the first dose. For those known to have completed a full HBV vaccination program, additional Hepatitis B vaccine need not be given. Emergency Contraception The exact risk of pregnancy following a sexual assault is estimated at about 2-4%, but depends to a large extent on where the woman was in her menstrual cycle and, of course, whether she was protected by some contraceptive method. Taking 2 medium-strength BCPs (Ovral) right away and again 12 hours later has been used successfully by many physicians to prevent pregnancy. Alternatively, 4 LoOvral can be taken immediately and again 12 hours later. Such a dosage is well-tolerated by most women, but half will experience nausea which might require anti-nausea medication. After using this protocol, the woman's normal menstrual cycle should not be disturbed and she will not have any withdrawal bleeding after she completes this 4-pill regimen. This method reduces the risk of pregnancy by 75%. Its exact mechanism of action is not known but may involve postponing ovulation and may involve prevention of implantation. Should a pregnancy occur despite the use of emergency contraception there is no convincing evidence of any harm to the fetus, although theoretical concerns will likely always be present. You need to advise your patient of these issues, and let her decide whether she wishes to take emergency contraception.. Whatever her decision, you should document in the medical record your discussion and her decision. Follow-up exam About 2 weeks after the assault, the patient should be re-examined for any lingering injury and also to provide reassurance that at least physically, everything is totally back to normal. At this time, she will have had a menstrual flow (typically), and she can have her follow-up labs (HIV, VDRL, Hep B) done at the same time. This will also allow you an opportunity to see how she is dealing with the psychological issues related to the assault. Ideally, serologic tests for syphilis and HIV infection should be repeated 6, 12, and 24 weeks after the assault if initial test results were negative For psychological reasons, some women may need to be seen earlier than 2 weeks to reassess their adaptation to this trauma. Medical Release After the patient has been examined and treated and all specimens collected, she may be released. She should not be released alone, but rather in the company of someone she knows and trusts. It is important that she feels she is going to a safe place. Write your Report Make this factual, but it need not be lengthy. Do not draw legal conclusions about whether a sexual assault occurred or did not occur. That is for the courts to decide. Give Evidence to Investigator Using a proper Chain-of-custody form, sign over the evidence to the MAA or other NIS representative, consisting of: Clothing Copy of Consent to Release Information Copy of your Medical Report Glass slide of oral specimen Glass slide of vaginal specimen Glass slide of rectal specimen Swabs of oral specimen Swabs of vaginal specimen Swabs of rectal specimen Filter paper with saliva Filter paper with 4-5 drops of patient blood Combings of head hair Combings of pubic hair 1 red-top tube of patient's blood Give Specimens to your Lab The laboratory specimens which you obtained for patient care reasons should go to your laboratory, but may be handled in the routine fashion and not following a Chain-of-Custody procedure. They will consist of: Gonorrhea plate from the mouth Gonorrhea plate from the cervix Gonorrhea plate from the rectum Chlamydia test kit from the cervix Pregnancy test specimen Red-top tube for VDRL, Hep B and HIV Give Instructions to Patient The patient should have everything she needs to get her follow-up medications. In addition, she should have written instructions on where to be and for what purpose: Antibiotics BCPs (antiemetics optional but recommended) Dates for weekly pregnancy tests Date for 2-week follow-up exam and labs (VDRL, Hep B and HIV) Date for 6, 12 and 24-week follow-up lab (VDRL, HIV) Name and phone number or location of law enforcement Investigator Name of Chaplain (or social service person) and phone number or location. The Special Case of Children Children who are victims of sexual assault need special attention and may require some modifications of the general outline. Small children may not have an appreciation of exactly what happened to them, or may be unable to express themselves. Some experienced examiners will have the child use dolls to demonstrate what happened During sexual assault of a prepubertal child, serious internal injuries may occur, including laceration of the vaginal wall and tearing of the uterus from its' supports at the top of the vagina. Rectal injury may occur. Because of this, it may be necessary to obtain other tests (upright abdomen looking for free air in the abdomen), or to examine a child under anesthesia to determine the extent of the injuries. Intra-abdominal injuries promptly diagnosed and treated will usually have an excellent prognosis. The same injuries diagnosed after peritonitis has become well-established are more grave. Normal Pregnancy Diagnosis of Pregnancy Pregnancy may be suspected in any sexually active woman, of childbearing age, whose menstrual period is delayed, particularly if combined with symptoms of early pregnancy, such as: Nausea (1st trimester) Breast and nipple tenderness (1st trimester) Marked fatigue (1st and 3rd trimesters) Urinary frequency (1st and 3rd trimesters) The patient thinks she's pregnant Early signs of pregnancy may include: Blue discoloration of the cervix and vagina (Chadwick's sign) Softening of the cervix (Goodell's sign) Softening of the uterus (Ladin's sign and Hegar's sign) Darkening of the nipples Unexplained pelvic or abdominal mass Pregnancy Tests The diagnosis of pregnancy is accurately made with a urine pregnancy test. Current test kits are highly specific and detect 35-30 mIU of HCG (human chorionic gonadotropin, the pregnancy hormone) per ml of urine. In other words, the pregnancy test will be turning from negative to positive at about the time of the first missed menstrual period. Collect a fresh urine specimen. First morning specimens are preferable in early pregnancy because they are more concentrated and more likely to be positive is only small amounts of pregnancy hormone are present. Place the correct number of drops of urine in the collecting area of the test kit. The precise number of drops, length of time to wait, and method of reading positive, negative, and control varies from manufacturer to manufacturer. In the event of an "equivocal" pregnancy test...one that is not really positive nor negative, additional urine can be put through the test kit to boost the sensitivity. Instead of using 3 drops of urine, you can use up to 6 drops of urine. This will virtually double the sensitivity of the test, while increasing the chance of a false positive by only a small amount. In an urgent situation, if a patient is unable to provide urine for the test, serum can be used in the urine test kit in place of urine. Draw blood into a test tube. Tape the test tube to the wall for about 10 minutes (allow it to clot). Using an eye dropper or a syringe with a needle, draw off a small amount of serum (the clear, watery part of the blood that's left at the top of the test tube after the blood has clotted). Use the serum instead of urine in the urine pregnancy test kit, drop for drop. If the test kit calls for 4 drops of urine, use 4 drops of serum. This is an imperfect solution, because the forms of HCG (pregnancy hormone) found in serum are somewhat different from the forms found in urine. Further, the serum proteins tend to sludge up the test kit, both mechanically and biochemically. That said, using serum instead of urine will work well enough for most purposes in an operational setting and can provide immediate insight into the patient's problem. Prenatal Care At the first prenatal visit, take a careful history, looking for factors that might increase the risk for the pregnant woman. Many providers use a questionnaire, filled out by the patient, as a starting point for this evaluation. A sample Prenatal Registration and Obstetrical Questionnaire form can be used for this purpose. One important aspect of prenatal care is education of the pregnant woman about her pregnancy, danger signs, things she should do and things she should not do. Many providers find it useful to give the woman printed material covering these issues that she can take with her. This allows her to read the material at a later time and to refer to it whenever she has questions. A sample Prenatal Information form can be printed and used. Routine visits: every 4 weeks until 28 weeks' gestation every 2-3 weeks until 36 weeks' gestation every week from 36 weeks to delivery At each prenatal visit: Check weight Typical weight gain is about a pound a week. This means 30 to 40 pounds for the entire pregnancy, although some physicians feel the ideal weight gain should be closer to 25 pounds. Weight gain is usually slow during the first 20 weeks. Then, there is usually rapid weight gain from 20 to 32 weeks. After that, weight gain generally slows and there may be little, if any weight gain during the last few weeks. If there is insufficient weight gain (below 13 pounds), there is concern that the baby may not be getting enough food. If there is sudden weight gain (more than 2 pounds in a week or more than 6 pounds in a month), this may be associated with the development of fluid retention due to pre-eclampsia (toxemia of pregnancy). Check blood pressure Blood pressure in early pregnancy will reflect pre-pregnancy levels. During the 2nd trimester, maternal blood pressures usually fall below prepregnancy levels. During the 3rd trimester, blood pressure usually goes back up to the pre-pregnancy level. Any sustained BP of 140/90 or greater is considered significant and may indicate the development of pre-eclampsia. Measure fundal height Use a tape measure to record the size of the uterus (technique described below). The fundal height, measured in cm, should be approximately equal to the weeks gestation, from mid-pregnancy until near term. Measurements falling within 1-3 cm of the expected value are considered normal. Fundal heights 4 cm different than expected are considered abnormal and suggest the need for further investigation. Listen for the heartbeat The normal rate is generally considered to be between 120 and 160 beats per minute. The rates are typically higher (140-160) in early pregnancy, and lower (120-140) toward the end of pregnancy. Past term, some normal fetal heart rates fall to 110 BPM. There is no correlation between heart rate and the gender of the fetus. Check for edema Swelling of the feet, ankles and hands is common during pregnancy. It can be uncomfortable for the patient, but she can be reassured that it will go away after delivery. Facial edema or any sudden increase in edema can be a sign of developing pre-eclampsia, so the BP should be checked. An effective treatment for edema is bedrest for 2-3 days, while drinking plenty of plain water and avoiding excessive salt. This will mobilize the extracellular salt and fluids, leading to a loss of several pounds through urination. In most cases, such treatment is not necessary as the edema itself is not medically threatening. Check protein and glucose A urine dipstick test for protein is generally negative or trace during pregnancy. If 1+ (30 mg/dl) or more, it is considered significant. Urine normally shows negative or trace glucose. If persistently 1/4 (250 gm/dl) or more, it is considered significant. Ask about fetal activity Although fetal movement can be documented by ultrasound as early as 7-8 weeks of pregnancy, fetal the mother does not usually feel movement until the 16th week (for women who have delivered a baby) to the 20th week (for women pregnant for the first time). Once they positively identify fetal movement, most women will acknowledge that they have been feeling the baby move for a week or two, but didn't realize that the sensation (fluttery movements) was from the baby. Movements generally increase in strength and frequency through pregnancy, particularly at night, when the woman is at rest. At the end of pregnancy (36 weeks and beyond), there is normally a slow change in movements, with fewer violent kicks and more rolling and stretching fetal movements. A sudden decrease in fetal movement is a danger sign that needs to be reported and investigated immediately. "Kick counts" are sometimes recommended to patients as a means of quantifying fetal movement. One common way of doing a kick count is to ask the woman to count each distinct fetal movement, starting from the time she awakens in the morning. When she reaches 10 movements or kicks, she is done counting for the day. If she gets to 12 noon and hasn't reached a count of 10 movements, she reports this to her provider and further testing is done. Any new symptoms The development of pain, bleeding, vaginal discharge or fluid loss, or neurologic symptoms (visual changes, disequilibrium) can be significant. Nutrition A pregnant woman should eat a normal, balanced diet for one person. This may prove difficult, particularly during the early part of the pregnancy when she may experience significant nausea. It may also prove difficult later in pregnancy when she feels hungry all the time. These women may find they do better by having more frequent (but smaller) meals, or snacks between meals of relatively nutritious but low caloric foods. Prenatal Vitamins It is customary for pregnant women to take a prenatal vitamin each day. In theory, it might be possible for a pregnant woman to obtain the right amount of essential vitamins and minerals through a careful and complete diet. In real life, it is difficult for most women to achieve such a diet, particularly the need for Folate. It is far simpler take a prenatal vitamin each day. Those living in nutritionally-deprived areas will particularly benefit from the addition of prenatal vitamins to their diet. Laboratory Tests Some routine lab tests are done on all pregnant women at different times during the pregnancy. Other tests are done for a specific indication. As early in pregnancy as feasible, obtain: Hemoglobin or hematocrit White blood count and platelet count Urinalysis Blood group and Rh type Atypical antibody screen Rubella antibody titer RPR or VDRL Hepatitis B screen HIV Pap Smear Chlamydia/Gonorrhea Subsequent lab tests consists of: Amniocentesis or CVS for women age 35 at 10-17 weeks Maternal serum AFP at 16-18 weeks Hemoglobin or hematocrit at 28 weeks Serum glucose at 1-hour post 50g glucose load at 28 weeks Administration of Rhogam to Rh negative women Other tests may be indicated, based on individual risk factors. These might include screening for Sickle Cell disease (or trait), thalassemia, G6PD, tuberculosis. Follow-up tests may also be needed, based on the original screen. For example, a woman found to be very anemic might be evaluated with serum folate and ferritin levels. A woman failing her glucose screening test will probably need a full glucose tolerance test. Ultrasound Scan Routine ultrasound scanning of all pregnant women early in pregnancy is recommended by some, but not all authorities in civilian settings. For women in an operational environment, a routine ultrasound scan early in pregnancy can be very useful, because it identifies those destined to miscarry, those with an ectopic pregnancy, and those whose gestational age does not agree with their LMP. Additional, medically-indicated ultrasound scans may also be appropriate. Ultrasound is used to evaluate vaginal bleeding or pain, and discrepancies between the measured size of the uterus and the expected size. It may be used to look for multiple gestations, such as twins or triplets, determine the position of the fetus, and assess fetal growth. Later in pregnancy, it may be used to evaluate fetal well-being, amniotic fluid volumes, and to estimate fetal weight. Estimating Gestational Age The estimated delivery date is calculated by adding 280 days to the first day of the last menstrual period. An alternative method of determining the due date is to add 7 days to the LMP, subtract three months, and add one year. These calculations are made easier with the use of a Gestational Age Calculator. One way to approximate a pregnancy's current gestational age is to use a tape measure to determine the distance from the pubic bone up over the top of the uterus to the very top. That distance, measured in centimeters, is approximately equal to the weeks of gestation, from about mid-pregnancy until nearly the end of pregnancy. This is known as MacDonald's Rule. If a tape measure is unavailable, these rough guidelines can be used: At 12 weeks, the uterus is just barely palpable above the pubic bone, using only an abdominal hand. At 16 weeks, the top of the uterus is 1/2 way between the pubic bone and the umbilicus. At 20-22 weeks, the top of the uterus is right at the umbilicus. At full term, the top of the uterus is at the level of the ribs. (xyphoid process). Ultrasound can be used to determine gestational age. Measurement of a crown-rump length during the first trimester (1-13 weeks) will give a gestational age that is usually accurate to within 3 days of the actual due date. During the second trimester (14-28 weeks), measurement of the biparietal diameter will accurately predict the due date within 10-14 days in most cases. In the third trimester, the accuracy of ultrasound in predicting the due date is less, with a plus or minus confidence range of as much as 3 weeks. A chart showing different ultrasound measurements at different gestational ages in shown in the Ultrasound Gestational Age Measurements chart. Fetal Heart Beat Although the fetal heart begins beating as early as the 5th week after the LMP, your ability to detect it will be limited by your equipment. An ultrasound machine usually will see a heartbeat by 5 to 6 weeks gestation if equipped with a vaginal probe. Abdominal ultrasound will usually see the heartbeat by the 7th-8th week of pregnancy. If you use a Doppler ultrasound fetal heartbeat detector, you can, with effort, usually hear the heartbeat by 12-14 weeks gestation and routinely after that. Using a DeLee stethoscope (equipped with a head-mount), you can sometimes hear the heartbeat by 16 weeks but unless you are practiced with it, you won't hear it until 20 weeks, at which time the mother can usually tell you that she feels the baby moving. Using a conventional stethoscope, you may never hear the fetal heartbeat. Disability Pregnancy causes many changes in women, not the least of which are change in weight and its' distribution, balance and increased vulnerability of ligaments and joints to stress. Because of these changes, the safe care of pregnant women requires that their normal work activities be modified. In the Navy, OPNAVINST 6000.1A is the instruction which provides the greatest detail of guidance for the administrative aspects of managing this disability. In the Marine Corps, MCO 5000.12d gives equivalent guidance. Maternal Skin Changes Over time, there is a darkening of the maternal skin, in predictable ways. Chloasma is a darkening of the facial skin, after the 16th week of pregnancy, particularly in women with darker complexions and significant exposure to the sun. After delivery, the skin clears, but for some individuals, a persistent darkening of the skin remains. Spider telangiectasias are small, bright red, star-shaped skin discolorations that blanch with direct compression and then return as soon as the compression is released. After delivery, they will largely resolve, but some may remain. Stretch marks occur primarily in late pregnancy and are due to a separation of the underlying collagen tissue. They are dark red. After delivery, they will gradually lighten, ultimately healing as fine, faint, silvery-gray lines. Who gets them and how severe they are is dependent on the genetic predisposition of the mother and the degree of mechanical stress placed on the skin. There are no scientifically-established methods to either prevent them or treat them. However, generations of women have applied cocoa butter to the skin in the belief that it is helpful. A "linea nigra" is a dark line running from the pubic bone up the center of the abdomen to the ribs. This appears late in pregnancy and is due to a combination of increasing concentration of melanocytes (skin cells capable of darkening) in that area, plus the high levels of melanocyte stimulating hormone produced by the placenta. Exercise in Pregnancy If the pregnancy is normal, moderate amounts of exercise are acceptable and desirable. Some restrictions are appropriate: Women should not start a new sport or exercise while pregnant, but may continue previous activities. Activities which require a fine sense of balance to preserve the woman's personal safety (horseback riding, downhill skiing, etc.) are inadvisable because pregnant women are inherently and unavoidably unstable in their balance. Because of pregnancy-induced changes in the supporting cartilage and ligaments (softening), the joints are relatively unstable. Thus, activities which place great stress on any joints are unwise. Nausea & Vomiting These are common during pregnancy but may be aggravated by strong smells (food, garbage, machine oil, etc.) and motion. Symptoms appear quite early and are usually mild, requiring no treatment, disappearing by the 16th week or sooner. Occasionally, these symptoms are severe and require intervention. If a pregnant woman states, "I can't keep anything down," and has ketones in her urine, she must be re-hydrated with crystalloid such as 5% dextrose in lactated Ringer's solution (D5LR). One liter is given in a short time (15-20 minutes), and the second liter given over an hour or two. Sometimes a third liter, given over several hours, will be necessary. While this rate of hydration would be much too fast for an older individual with heart disease, the cardiovascular system of a young, healthy, pregnant woman is very "stretchy" and will tolerate such rapid infusions well. After IV therapy, the woman is generally feeling much better and can return to her duties. If this rehydration is insufficient to suppress her symptoms, then a more prolonged course of therapy is recommended. Try to avoid antiemetics in the pregnant patient as the long-term consequences of most of the drugs on a developing pregnancy are not well established. Nonetheless, the long-term results of protracted vomiting, dehydration, electrolyte imbalance and ketosis are known and unfavorable to the pregnancy, so if it appears that IV hydration alone is not controlling the symptoms, move to antiemetics with dispatch. Conventional doses of Antihistamines (Benadryl), Anticholinergics (Scopolamine), Compazine, Phenergan, and others have all been used to good advantage in these situations. Heartburn This common pregnancy-related ailment is caused by leaking of stomach acid into an unprotected esophagus, causing a chemical burn known as heartburn. The best relief is obtained by sucking on an antacid tablet until the pain goes away (one or two tablets). Chewing and swallowing the tablets will also be effective but usually requires more tablets. If antacids are not available, eating or drinking anything will give some relief as it will partially buffer the acid in the esophagus and rinse it back down into the stomach. Pepcid AC can also be used safely during pregnancy. Sciatica Sciatica occurs in 30% of pregnant women and is characterized by sharp pains in the hip and buttock on one or both sides, shooting down the back of the thigh. There may also be numbness of the anterior thigh on the effected side. This is due to compression of the sciatic nerve as it exits the spinal column in the small of the back. It is provoked by pregnancy and disappears after delivery. Treatment of sciatica: Avoid standing for long periods of time. When sleeping, assume a semi-fetal position, with both knees drawn up and a pillow placed between the knees. When sitting, make sure the knees are slightly flexed so that the knees are at least level with the hips or slightly higher than the hips. Sleeping with one leg straight and the other knee drawn up is a bad position as far as the back is concerned. Torsion is placed on the lower spine, aggravating any pressure on the sciatic nerve that may be present. Sleeping on the side while pregnant is a good, idea, but both knees should be drawn up (flexing the thighs). Either side will work well. In order to maintain this semi-fetal position comfortably, it is necessary to place a small pillow, folded blanket or towel between the patient's knees. This will absorb moisture, separate the legs, minimizing skin-to-skin contact, and provide additional support to the legs. With practice, this position will become very comfortable. Carpal Tunnel Syndrome Approximately 30% of pregnant women will develop numbness in one or both hands following the distribution of the median nerve. (index finger, middle finger, and medial surface of ring finger, with sparing of the lateral surface of the ring finger and the little finger). This is due to swelling and compression of the median nerve as it passes through the "carpal tunnel" in the wrist. The dominant hand is more frequently effected. It is usually worse in the morning and improved in the evening. After delivery, the condition goes away gradually. No treatment is necessary for this condition, so long as the motor portion of the nerve is still functioning normally. When treatment is necessary, splinting the wrist in a "cockup splint" will be helpful. Injection of the carpal tunnel with steroids may also be done (after 24 weeks of pregnancy). Rarely, surgery may be necessary to free up the median nerve, although this is almost never required during pregnancy. Upper Respiratory Infections Most pregnant women will have at least one URI while pregnant. Drugs are to be avoided, but the following medications may be used to good advantage if necessary: PRIVATEAcetaminophen This will effectively relieve muscle aches and fever. It is considered safe during pregnancy. (Category B drug, the same as prenatal vitamins.)Guaifenesin This expectorant is considered safe during pregnancy.Pseudoephedrine This sympathomimetic is a very effective decongestant. Its use during the 1st trimester is sometimes restricted because of indirect data suggesting a slight increased risk of fetal malformations. Late in the third trimester, its' use is again restricted because of its' somewhat unpredictable cardiovascular effects.Triprolidine An effective antihistamine, it is considered safe during pregnancy. Antibiotics during Pregnancy Because of various infections, the need to place pregnant women on antibiotics may arise. While this listing is necessarily incomplete due to space considerations, it will give you a guide to selecting antibiotics for these women.
PRIVATEPenicillinsSafe during pregnancy. CephalosporinsSafe during pregnancy. ErythromycinSafe during pregnancy. AzithromycinSafe during pregnancy. Tetracycline (Doxycycline)UNSAFE AT ANY TIME DURING PREGNANCY. MetronidazoleSafe after 14 weeks. Avoid single-dose therapy. Safety prior to 14 weeks not well-established. AminoglycosidesBasically safe during pregnancy, but renal and ototoxicity are potential problems if the dose is high or prolonged. ClindamycinSafe during pregnancy. ChloramphenicolProbably safe prior to 28 weeks Sulfa drugsSafe prior to 34 weeks. After that, babies may develop jaundice if exposed to sulfa. QuinineOnly to be used in life-threatening, chloroquine-resistant P. Falciparum infections MiconazoleSafe during pregnancy. ClotrimazoleSafe during pregnancy. QuinacrineProbably safe during pregnancy. ChloroquineWith prolonged or high doses may cause congenital defects. PyrimethamineSafe after 1st trimester. Add folic acid supplement. TrimethoprimSafe after 1st trimester. Add folic acid supplement. PrimaquineMay cause hemolytic anemia in the presence of G6PD deficiency. You may use it if needed. 
Other Drugs during Pregnancy Local anesthetics (Xylocaine) may be used with safety, although the addition of epinephrine to them is problematic. Epinephrine may have unpredictable effects on the maternal cardiovascular system (and hence the blood flow to the baby), so epinephrine is generally to be avoided. Aspirin should not be taken as it may lead to significant fetal hemorrhage. Codeine, Demerol, Morphine and other narcotics may be used as needed at any stage of pregnancy, but the addictive potential should be recognized. Other than the risk of fetal drug withdrawal syndrome, these major pain relievers are considered safe for use during pregnancy. Immunization during Pregnancy
Tetanus BoosterSafe during pregnancy. Diphtheria ToxoidSafe during pregnancy. Hepatitis B vaccineMay safely be safely given to pregnant women who are at high risk of exposure.Influenza or pneumococcal immunizationMay be given to pregnant women if they are at increased risk of these conditions.Measles, mumps and rubella vaccineDo not be give to a woman while pregnant but defer until after the pregnancy.Yellow FeverCan and should be given to pregnant women traveling to areas where Yellow Fever endemic.PolioCan and should be given to pregnant women traveling to areas where polio is endemic.Anthrax ImmunizationDo not administer during pregnancy.Immune globulinMay be given any time it is clinically indicated.
Thermal Stress Fetal enzyme systems may not function properly if subjected to unusually high temperatures. In laboratory animals, elevation of core temperature is associated with fetal losses. For this reason, pregnant women are generally restricted from saunas and Jacuzzis. The important thing to avoid is elevation of the core temperature. Any activity which may lead to an elevation of core temperature should be restricted. This would include sedentary exposure to high ambient temperatures which would otherwise be tolerated by a non-pregnant person, or moderate exercise in moderately-elevated temperatures. Aboard warships, high ambient temperatures are often found in the: Engine spaces Laundry Mess decks Noise Pregnant women should wear hearing protection when exposed to ambient noise levels above 84dBA, including infrequent impact noise. (So should non-pregnant women and men.) Brief exposure (5 minutes per hour or less) of hearing-protected pregnant women to ambient noise above 84dBA in order to transit high noise areas is probably safe. Prolonged exposure to this level of noise is not recommended. Pregnant women should avoid any exposure to ambient noise greater than 104dBA (corresponding to the need for double hearing protection), unless absolutely essential for quickly moving through a high noise area. The abdominal wall muffles (attenuates) the noise only somewhat and these very noisy areas may pose significant problems for the developing fetus. Vibration Low-Frequency Whole Body Vibration is the type of shaking vibration one might experience if operating a jackhammer or driving at high speed over a highway with many potholes. It is to be avoided during pregnancy. Chemical Solvents Organic solvents, such as turpentine, fuel, oils, lubricants, and paint thinner may have adverse effects on a developing fetus. The greatest risk comes from ingestion of these solvents, or by chemical spills with contamination of the skin. Inhalation, though less likely to delivery significant quantities of the material, should also be avoided. Heavy Metals It is very important to avoid maternal exposure to lead, cadmium and mercury. X-rays during Pregnancy All things being equal (which they never are), it is better to avoid x-rays while pregnant. If indicated, (chronic cough, possible fracture, etc.), then x-rays are acceptable. If you need an x-ray for a pregnant patient, go ahead and get it, but try to shield the baby with a lead apron to minimize the fetal exposure. In your zeal to shield the pregnant abdomen, be careful not to shield so much that the value of the x-ray is diminished. If the shielding is too high while obtaining a chest x-ray, you will have to obtain a second x-ray to visualize the area shielded during the first x-ray. Radiation Exposure There appears to be a threshold for fetal malformation or death of at least 10 Rads, below which, biologic effects cannot be demonstrated. Allowing for a 10-fold margin of safety, it does not appear that any exposure below 1 Rad will have any harmful effects. It would take about a thousand chest x-rays to deliver this amount of radiation to the unshielded maternal pelvis. At the same time, our knowledge of the biologic effects or radiation may be incomplete, so it is better for pregnant women, as a rule, to avoid any unnecessary exposure to ionizing radiation, and to use appropriate shielding when it is necessary. CRT Use and Pregnancy There is no good evidence that working in front of a CRT (Cathode Ray Tube) poses any threat for the pregnant woman, either from electromagnetic radiation (EMR) or from eyestrain. Ergonomics are important for all sitting personnel, and particularly pregnant women. Good low back support, correct height for the CRT, wrist support and proper positioning of the legs (with the thighs flexed slightly so the knees are at least level with the hips, if not slightly higher than the hips), will contribute to the comfort and performance of these personnel. Diving while Pregnant Simply stated, pregnant women should not dive. It poses health risks to themselves and their fetus. Pregnant women have increased amounts of body fat and 3rd-space fluid retention, each of which tends to trap nitrogen and other gasses due to poor circulation through those areas. This predisposes them to decompression sickness and air embolism. While fetuses do not form gas bubbles more easily than women, even a few bubbles are likely to be very dangerous to the fetus because of fetal circulation. In adults, bubbles tend to be filtered by the pulmonary circulation through the lungs, but in fetuses, there is a bypass of the lung circulation through the foramen ovale and ductus arteriosus. This means that bubbles will not be filtered but may instead go directly to the brain or coronary vessels, possibly causing stroke or death. There is also evidence that diving may produce birth defects, including limb reductions, cardiac malformations, and other problems, although this area has not been carefully researched. Hyperbaric treatment The effects of controlled hyperbarism on pregnant women and fetal development are uncertain. In eastern Europe, scientists using relatively low pressures but repeatedly and for long periods of time have reported no particular problems with it. One study suggests that while in a hyperbaric atmosphere, the fetus changes its' circulatory flow in the direction of neonatal flow patterns (with narrowed or closed ductus arteriosus and foramen ovale). Upon return to normal barostatus, the flow again reverses to the normal fetal flow pattern. Whether this change poses any long-term problems for the fetus is unknown. Based on these concerns, it is inadvisable to allow any pregnant woman to dive or enter a hyperbaric chamber unless strongly indicated for medical reasons. If an accident occurs in which it would be desirable to place the pregnant woman in a hyperbaric chamber, the risks to the fetus (mainly theoretical) must be balanced against the risks to the mother of not undergoing hyperbaric treatment. Pregnant Aircrew Members Aircrew status while pregnant is a complex issue, involving fetal risks, maternal risks and aircrew performance. The maternal risks include decreased balance, decreased motion tolerance, and decreased g-tolerance, gas compression/recompression effects. During the second and third trimester, placental abruption caused by the shearing force of inadvertently falling or striking the abdomen violently is a relatively common occurrence. Fetal risks include exposure to noise, heat, chemicals, organic solvents, and low-frequency, whole-body vibration. For these reasons, there is general agreement among the services to restrict pregnant aircrewman from participating in high-performance aircraft flights. There is less agreement in the area of helicopters and multiengine, fixed-wing aircraft. Whether to allow a pregnant aircrewmember to continue her flight duties should be individualized, after considering the stage of pregnancy, the presence or absence of risk factors for her pregnancy or her flight crew performance, her individual service's rules, and the degree of exposure to potentially harmful stressors in the aviation environment. Abnormal Pregnancy Miscarriage Miscarriage is the layman's term for spontaneous abortion, an unexpected 1st trimester pregnancy loss. Since laymen may misunderstand the term spontaneous abortion, the word "miscarriage" is sometimes substituted. Abortion Loss of a pregnancy during the first 20 weeks of pregnancy, at a time that the fetus cannot survive. Such a loss may be involuntary (a "spontaneous" abortion), or it may be voluntary ("induced" or "elective" abortion). Abortions are further categorized according to their degree of completion. These categories include: Threatened Inevitable Incomplete Complete Septic Such losses are common, occurring in about one out of every 6 pregnancies. For the most part, these losses are unpredictable and unpreventable. About 2/3 are caused by chromosome abnormalities incompatible with life. About 30% are caused by placental malformations and are similarly not treatable. The remaining miscarriages are caused by miscellaneous factors but are not usually associated with: Minor trauma Intercourse Medication Too much activity Following a miscarriage, the chance of having another miscarriage with the next pregnancy is about 1 in 6. Following two miscarriages in a row, the odds of having a miscarriage with the next pregnancy is still about 1 in 6. After three consecutive miscarriages, the risk of having a fourth is greater than 1 in 6, but not very much greater. Threatened Abortion A threatened abortion means the woman has experienced symptoms of bleeding or cramping. At least one-third of all pregnant women will experience these symptoms. Half will go on to abort spontaneously. The other half will see the bleeding and cramping disappear and the remainder of the pregnancy will be normal. These women who go on to deliver their babies at full term can be reassured that the bleeding in the first trimester will have no effect on the baby and that you expect a full-term, normal, healthy baby. Treatment of threatened abortion should be individualized. Many obstetricians recommend bedrest in some form for women with a threatened abortion. There is no scientific evidence that such treatment changes the outcome of the pregnancy in any way, although some women may feel better if they are at rest. Other obstetricians feel that being up and active is psychologically better for the patient and will not change the risk of later miscarriage. Among these active women, strenuous physical activity is usually restricted, as is intercourse. In an operational setting, bedrest may prove very useful. While you are not changing the outcome of the pregnancy (abnormal chromosomes will remain abnormal despite increased maternal rest), you may effectively postpone the miscarriage until a safer time. (days to possibly a week or two) Complete Abortion A complete abortion means that all tissue has been passed through the cervix. This is the expected outcome for a pregnancy which was not viable from the outset. Often, a fetus never forms (blighted ovum). The bleeding and cramping steadily increases, leading up to an hour or two of fairly intense cramps. Then the pregnancy tissue is passed into the vagina. An examination demonstrates the active bleeding has slowed or stopped, there is no tissue visible in the cervix, and the passed tissue appears complete. Save in formalin any tissue which the patient has passed. Rh negative women receive an injection of Rhogam (hyperimmune Rh globulin) within 3 days of the abortion. It may still be effective in preventing Rh sensitization if given within 7-10 days. They are encouraged to have a restful day or two and a follow-up examination in a week or two. Bleeding similar to a menstrual flow will continue for a few days following the miscarriage and then gradually stop completely. A few women will continue to spot until the next menstrual flow (2-6 weeks later). Women seeking another pregnancy as soon as possible are often advised to wait a month or two to allow them to re-establish a normal uterine lining and to replenish their reserves. Prolonged waiting before trying again is not necessary. Some physicians recommend routinely giving a uterotonic drug (such a Methergine 0.2 mg PO TID x 2 days) to minimize bleeding and encourage expelling of any remaining fragments of tissue. It also may increase cramping and elevate blood pressure. Antibiotics (Doxycycline, amoxicillin) are likewise prescribed by some. While the usefulness of these medications in a civilian setting depends on circumstances, they are probably very wise in an operational setting, particularly where sanitation may be suboptimal. If fever is present, IV broad-spectrum antibiotics are wise, to cover the possibility that the complication of sepsis has developed. If the fever is high and the uterus tender, septic abortion is probably present and you should make preparations for D&C (or Medical Evacuation if D&C is not available locally. If hemorrhage is present, bedrest, IV fluids, oxygen, and blood transfusion may be necessary. Continuing hemorrhage suggests an "incomplete abortion" rather than a "complete abortion" and your treatment should be reconsidered. Incomplete Abortion With an incomplete abortion, some tissue remains behind inside the uterus. These typically present with continuing bleeding, sometimes very heavy, and sporadic passing of small pieces of pregnancy tissue. When available, ultrasound may reveal the presence of identifiable tissue within the uterus. Serial quantitative HCG levels can be measured if there is doubt about the completeness of a miscarriage. Left alone, some of these cases of incomplete abortion will eventually resolve spontaneously, but so long as there are non-viable pieces of tissue inside the uterus, the risks of bleeding and infection continue. Treatment consists of converting an incomplete abortion into a complete abortion. Usually, this is done with a D&C (dilatation and curettage). This minor operation can be performed under local anesthesia and takes just a few minutes. If D&C is not available, bedrest and oxytocin, 20 units (1 amp) in 1 Liter of any crystalloid IV fluid at 125 cc/hour may help the uterus contract and expel the remainder of the pregnancy tissue, converting the incomplete abortion to a complete abortion. Alternatively, ergonovine 0.2 mg PO or IM three times daily for a few days may be effective. If fever is present, broad-spectrum antibiotics are wise, particularly if D&C is not imminent. Any tissue fragments visibly protruding from the cervical os can be grasped with a ring or dressing forceps and gently pulled straight out. This simple and safe procedure will have a beneficial effect on the bleeding. Do not attempt to insert any instruments into the uterus unless you have had training to do this since you may cause more harm than simply leaving things alone. If hemorrhage is present, bedrest, IV fluids, oxygen, and blood transfusion may be necessary. The decision for medical evacuation is difficult. Moving the patient will usually increase the rate of bleeding. At the same time, uncontrolled hemorrhage will ultimately be fatal. In general, an easy MEDEVAC is preferable to continued bedrest in the face of unrelenting bleeding. If the MEDEVAC is dangerous, rough or lengthy, bedrest and medication may be more advisable. Inevitable Abortion Inevitable abortion means that a miscarriage is destined to occur, but no tissue has yet been passed. This is sometimes called a "missed abortion." This diagnosis is best made by ultrasonic visualization of the fetal heart and noting no movement. Alternatively, demonstrating no growth of the fetus over a one week period in early pregnancy confirms an inevitable abortion. When ultrasound is not available, the diagnosis of inevitable abortion is made clinically. This clinical diagnosis is based on the presence of life-threatening maternal hemorrhage, or bleeding and cramping associated with a dilated cervix. In such clinical circumstances, the diagnosis of inevitable abortion can be made with confidence. When bleeding is heavy, an inevitable abortion is treated as though it were an incomplete abortion. If bleeding is not heavy, then treatment may be postponed until the patient is transferred to a definitive care area. At the definitive care area, two alternative approaches are considered: D&C or awaiting a spontaneous abortion. Each approach has its own merits and limitations: Awaiting a spontaneous abortion offers the benefit of avoiding surgery, but commits the patient to a day or more of heavy bleeding and cramping. A few of these women will experience an incomplete abortion and will need to have a D&C anyway. Performing an automatic D&C has the benefit of quickly resolving the issue of a missed abortion, but commits the patient to a surgical procedure which carries some risks. Septic Abortion During the course of any abortion, spontaneous or induced, infection may set in. Fever, chills, uterine tenderness and occasionally, peritonitis characterize such infections. The responsible bacteria are usually a mixed group of Strep, coliforms and anaerobic organisms. These patients display a spectrum of illness, ranging from mild, to very severe. Usual treatment consists of bedrest, IV antibiotics, uterotonic agents, and complete evacuation of the uterus. If the patient does not respond to these measures and is deteriorating, surgical removal of the uterus, tubes and ovaries may be life-saving. If your patient responds well and quickly to IV antibiotics and bedrest, you may safely continue your treatment. Remember, though, that she has the potential for becoming extremely ill very quickly and transfer to a definitive care facility should be considered. Evacuation of the uterus can be initiated with oxytocin, 20 units (1 amp) in 1 Liter of any crystalloid IV fluid at 125 cc/hour or ergonovine 0.2 mg PO or IM three times daily. If the patient response is not favorable, D&C is the next step. IV antibiotics should be started immediately. Reasonable antibiotic choices parallel those for PID, and include (Center for Disease Control, 1998): Doxycycline 100 mg PO or IV every 12 hours, PLUS either: Cefoxitin, 2.0 gm IV every 6 hours, OR Cefotetan, 2.0 gm IV every 12 hours This is continued for at least 48 hours after clinical improvement. The Doxycycline is continued orally for 10-14 days. ALTERNATIVE ANTIBIOTIC REGIMEN: Clindamycin 900 mg IV every 8 hours, PLUS Gentamicin, 2.0 mg/kg IV or IM, followed by 1.5 mg/kg IV or IM, every 8 hours This is continued for at least 48 hours after clinical improvement. After IV therapy is completed, Doxycycline 100 mg PO BID is given orally for 10-14 days. Clindamycin 450 mg PO daily may also be used for this purpose. ANOTHER ALTERNATIVE ANTIBIOTIC REGIMEN: Ofloxacin 400 mg IV every 12 hours, PLUS Metronidazole 500 mg IV every 8 hours ANOTHER ALTERNATIVE ANTIBIOTIC REGIMEN: Ampicillin/Sulbactam 3 g IV every 6 hours, PLUS Doxycycline 100 mg IV or orally every 12 hours. ANOTHER ALTERNATIVE ANTIBIOTIC REGIMEN: Ciprofloxacin 200 mg IV every 12 hours, PLUS Doxycycline 100 mg IV or orally every 12 hours, PLUS Metronidazole 500 mg IV every 8 hours. Unruptured Ectopic Pregnancy A woman with an unruptured ectopic pregnancy may have the typical unilateral pain, vaginal bleeding, and adnexal mass described in textbooks. Alternatively, she may have minimal symptoms. A sensitive pregnancy is almost invariably positive. Patients with a positive pregnancy test and unilateral pelvic pain or tenderness may have an unruptured ectopic pregnancy and should have an ultrasound scan to confirm the placement of the pregnancy. If ultrasound is not available, then it is best to arrange for medical evacuation. Alternative diagnoses which can cause similar symptoms include a corpus luteum ovarian cyst commonly seen in early pregnancy, or occasionally appendicitis. PID is characterized by bilateral rather than unilateral pain. With a threatened abortion, the pain is central or suprapubic and the uterus itself may be tender. While awaiting MEDEVAC, the following are wise precautions: Keep the patient on strict bedrest. She is less likely to rupture while lying absolutely still. Keep a large-bore (#16) IV in place. If she should suddenly rupture and go into shock, you can respond more quickly. Know her blood type and have a plan for possible transfusion. A gentle, smooth MEDEVAC is preferable to a rough one, even if it takes longer. The vibration during a helicopter ride or the jostling over rough roads in an ambulance or truck may provoke the actual rupture. Try to minimize this risk and be prepared with IV lines, IV fluids, oxygen, MAST (PASG) equipment, etc. If she develops peritoneal symptoms (right shoulder pain, rigidity, or rebound tenderness), she may be starting to rupture and you should react appropriately. Ruptured Ectopic Pregnancy Women with a ruptured ectopic pregnancy will have pain, sometimes unilateral and sometimes diffuse. Right shoulder pain suggests substantial blood loss. Within a few hours (usually), the abdomen becomes rigid, and the patient goes into shock. Sensitive pregnancy tests are positive. Ultrasound can show fluid in the cul du sac but often fails to identify the ectopic pregnancy itself. Nonetheless, ultrasound, when available, can be a useful diagnostic aid in ruling out the presence of a normal, intrauterine pregnancy. When ultrasound is unavailable, culdocentesis can demonstrate the presence of significant amounts of non-clotting blood in the abdomen. While this doesn't confirm a ruptured ectopic pregnancy, it is strongly suggestive of that. It provides a strong indication for surgical intervention. Palpate the uterus to determine its' shape and orientation. Put a single-tooth tenaculum on the posterior lip of the cervix. Pull the cervix toward you, straightening the uterus and stabilizing the posterior vaginal fornix. After prepping with antiseptic, penetrate the posterior fornix in the midline with a spinal needle attached to a syringe. This will hurt. You will reach the peritoneal cavity in less than 1 cm. Aspirate for fluid. Clear peritoneal fluid means no internal bleeding. Blood-tinged fluid usually means a traumatic tap. Bloody fluid means some bleeding, but not much. Gross blood suggests active bleeding. If there is doubt about the concentration of the blood in the specimen, perform a hematocrit on the aspirated fluid and compare it to the patient's hematocrit. Treatment is immediate surgery to stop the bleeding. If surgery is not an available option, stabilization and medical evacuation should be promptly arranged. While awaiting MEDEVAC: Give oxygen, IV fluids and blood according to ATLS guidelines. Keep the patient at absolute rest. Monitor urine output hourly with a Foley catheter. Take frequent vital signs to detect shock. Consider MAST trousers (PASG). If abdominal surgery is not available, the outlook for a patient with a ruptured ectopic pregnancy is fair. Aggressive fluid and blood replacement, oxygen and complete bedrest will result in about a 50/50 chance of survival. If this approach is necessary, remember: Try to maintain the urine output between 30 and 60 ml/hour. If the pulse is >100 or urine output <30, she needs more fluid. If she becomes short of breath and the lung sounds become "crackly," slow down the fluids as she probably is becoming fluid overloaded. If she becomes short of breath and the lungs sounds dry, increase the fluids and give blood as she is probably anemic and in need of more oxygen carrying capacity. As she loses blood into the abdomen, she will become distended. If she becomes so distended she can't breath, put a chest tube into the abdomen through a small, midline incision just below the umbilicus to drain off fluid or blood so she can breath. A MAST or PASG Suit can be very helpful in tamponading the internal bleeding. Seriously consider it in this situation. She may ultimately require as many as 15 or 20 units of blood. Blood Transfusion Incomplete abortion and ruptured ectopic pregnancy are two of the most common medical emergencies requiring blood transfusion in women. In a hospital setting, standard blood banking procedures apply, with the use of carefully cross-matched blood components as needed by the clinical situation. In operational settings, standard blood banking procedures may not be applicable or available. In these cases, direct donor to victim transfusion can be life-saving. Use a donor with O negative blood ("Universal Donor"). Don't try to match, for example, a B+ victim to a B+ donor. While improvements in the accuracy of blood type records have been made, there is still a significant inaccuracy rate (as high as 5%) in the medical record laboratory reports and dog tags. If you try to match a B+ victim to a B+ donor (type-specific blood transfusion), you are twice taking a 5% risk of a mismatch. It is safer to take that risk only once. Arrange IV tubing so that there is a large-bore needle at each end. This is facilitated by use of a 3-way stopcock. If this is not available, you can simply cut off the tubing at the end and insert it into the hub of a needle. Sterile petroleum jelly can provide a seal and the needle is held tightly to the IV tubing with adhesive tape. Position the donor about 3 feet higher than the victim. With the victim in a lower bunk, the donor would be in an upper bunk. With the victim on the floor or on the deck, the donor would be on a cot or packing crate. Insert the IV into the donor and let the blood flow downhill through the tube until it reaches the other end. Clamp the tubing just long enough to insert the other end into the victims IV or vein. Unclamp the tubing and allow time for about 1 unit (500 cc) of blood to flow into the victim. The exact amount of time would depend on the caliber of the tubing and needle, length of the tubing, height of the donor above the victim and doubtless other factors. In practice, allow about 10 minutes, but be prepared to stop it earlier if the donor becomes light-headed or dizzy. Because fresh, whole blood has better oxygen-carrying capacity than banked units of packed RBCs, and it is prewarmed, and because it contains platelets, clotting factors and serum proteins, each unit has about twice the clinical impact of a unit of packed cells from the bank. If, based on your clinical observation, you believe a patient would benefit from two units of PRBCs from a blood bank, they will generally do well with a single unit of fresh, whole blood. After the patient is transferred to a definitive care facility, it will be easier for them to identify the true, native blood type (major and minor blood groups) if they have a sample of blood taken from the patient prior to any transfusions. If time permits and the tactical situation allows for it, try to draw a single red-topped tube of the victim's blood prior to transfusion that you can send along with the MEDEVAC for use by blood banks further up the line. First Trimester Trauma During the first trimester, the uterus is protected within the pelvic bones. Trauma during this time will either be so severe as to cause a miscarriage (spontaneous abortion or fetal death), or else it will have no effect. Miscarriage is a common event, normally occurring in one out of every 5 or 6 pregnancies. While trauma can cause 1st trimester pregnancy loss, it is exceedingly rare in comparison with other causes of miscarriage. Catastrophic trauma includes such types of injury as maternal death, hemorrhagic shock, multiple compound fractures of the extremities, liver and spleen ruptures, to name a few. Catastrophic trauma during the first trimester is associated with subsequent miscarriage. Non-catastrophic trauma includes bumps, bruises, fractures of small bones (fingers, toes), minor burns, etc. While such non-catastrophic injuries may be serious enough to require treatment, they are not associated with miscarriages. Later Trauma Trauma occurring during the second and third trimester has different clinical consequences than during the first trimester. During the second and third trimester, even relatively minor trauma can have significant adverse effects on the fetus. Such adverse effects include placental abruption, preterm labor, premature rupture of the membranes, uterine rupture, and direct fetal injury. Rapid acceleration, deceleration, or a direct blow to the pregnant abdomen can cause shearing of the placenta away from its underlying attachment to the uterus. When this happens (placental abruption), the detached area will bleed and the detached area of the placenta will no longer function to supply oxygen to the fetus. A complete abruption is a disastrous event, life-threatening to both the fetus and the mother. Partial placental abruptions may range the full gamut from insignificant to the striking abnormalities seen in complete abruptions. Premature labor may be provoked. In these cases, regular uterine contractions begin shortly after the trauma (within 4 hours) and progress steadily and result in delivery. Premature rupture of the fetal membranes can also occur, within the first 4 hours of injury and usually result in a premature delivery. Direct fetal injury may occur, resulting in contusions, fractures or fetal death. Uterine rupture can occur and usually result in the loss of the fetus. The severity of the maternal injury may not correlate well with the frequency of adverse pregnancy outcome. Even minor trauma can have very serious consequences for the pregnancy. The adverse effects, when they occur, are immediate (within the first few days of the trauma). There is probably no increased risk of preterm delivery, depressed Apgar scores, cesarean section or neonatal length of stay, after excluding the following immediate adverse effects: Placental abruption within the first 72 hours of injury. Rupture of membranes within 4 hours of injury. Onset of labor within 4 hours of injury that resulted in delivery during the same hospitalization. Fetal death within 7 days of the traumatic event. Uterine contractions following trauma are common, although premature delivery caused by preterm labor is not. Actual preterm delivery resulting from premature labor (in the absence of abruption) probably occurs no more frequently among traumatized women than the general population. Placental Abruption Placental abruption is also known as a premature separation of the placenta. All placentas normally detach from the uterus shortly after delivery of the baby. If any portion of the placenta detaches prior to birth of the baby, this is called a placental abruption. A placental abruption may be partial or complete. A complete abruption is a disastrous event. The fetus will die within 15-20 minutes. The mother will die soon afterward, from either blood loss or the coagulation disorder which often occurs. Women with complete placental abruptions are generally desperately ill with severe abdominal pain, shock, hemorrhage, and a rigid and unrelaxing uterus. Partial placental abruptions may range from insignificant to the striking abnormalities seen in complete abruptions, Clinically, an abruption presents after 20 weeks gestation with abdominal cramping, uterine tenderness, contractions, and usually some vaginal bleeding. Mild abruptions may resolve with bedrest and observation, but the moderate to severe abruptions generally result in rapid labor and delivery of the baby. If fetal distress is present (and it sometime is), rapid cesarean section may be needed. Because so many coagulation factors are consumed with the internal hemorrhage, coagulopathy is common. This means that even after delivery, the patient may continue to bleed because she can no longer effectively clot. In a hospital setting, this can be treated with infusions of platelets, fresh frozen plasma and cryoprecipitate. In an operational setting where these products are unavailable, fresh whole blood transfusion will give good results. Patients in an operational setting thought to have at least some degree of placental abruption should be transferred to a definitive care setting. While transporting her, have her lie on her left side, with IV fluid support. Placenta Previa Normally, the placenta is attached to the uterus in an area remote from the cervix. Sometimes, the placenta is located in such a way that it covers the cervix. This is called a placenta previa. There are degrees of placenta previa: A complete placenta previa means the entire cervix is covered. This positioning makes it impossible for the fetus to pass through the birth canal without causing maternal hemorrhage. This situation can only be resolved through cesarean section. A marginal placenta previa means that only the margin or edge of the placenta is covering the cervix. In this condition, it may be possible to achieve a vaginal delivery if the maternal bleeding is not too great and the fetal head exerts enough pressure on the placenta to push it out of the way and tamponade bleeding which may occur. Clinically, these patients present after 20 weeks with painless vaginal bleeding, usually mild. An old rule of thumb is that the first bleed from a placenta previa is not very heavy. For this reason, the first bleed is sometimes called a "sentinel bleed." Later episodes of bleeding can be very substantial and very dangerous. Because a pelvic exam may provoke further bleeding it is important to avoid a vaginal or rectal examination in pregnant women during the second half of their pregnancy unless you are certain there is no placenta previa. The location of the placenta is best established by ultrasound. If ultrasound is not available, one reliable clinical method of ruling out placenta previa is to check for fetal head engagement just above the pubic symphysis. Using a thumb and forefinger and pressing into the maternal abdomen, the fetal head can be palpated. If it is deeply engaged in the pelvis, it is basically impossible for a placenta previa to be present because there is not enough room in the birth canal for both the fetal head and a placenta previa. An x-ray of the pelvis (pelvimetry) can likewise rule out a placenta previa, but only if the fetal head is deeply engaged. Otherwise, an x-ray will usually not show the location of the placenta. Patients suspected of having a placenta previa in an operational setting need expeditious transport to a definitive care setting where ultrasound and full obstetrical services are available. Toxemia of Pregnancy Toxemia of pregnancy is a clinical syndrome characterized by elevated blood pressure, protein in the urine, fluid retention and increased reflexes. It occurs only during pregnancy and resolves completely after pregnancy. It is seen most often as women approach full term, but it can occur as early as the 22nd week of pregnancy. Its cause is unknown, but it occurs more often in: Women carrying their first child Multiple pregnancies Pregnancies with excessive amniotic fluid (polyhydramnios) Younger (<17) and older (>35) women Ordinarily, blood pressure decreases during the middle trimester, compared to pre-pregnancy levels. After the middle trimester, blood pressure tends to rise back to the pre-pregnancy levels. Sometimes, blood pressure becomes elevated. Sustained blood pressures exceeding 140/90 are considered abnormal and may indicate the presence of toxemia of pregnancy. For women with pre-existing hypertension, a sustained worsening of their hypertension over pre-pregnancy levels by 30 systolic and 15 diastolic is often used to indicate the possible presence of super-imposed toxemia. The presence of hypertension and proteinuria are essential to the diagnosis of toxemia of pregnancy. Pregnant women can normally lose up to 200 mg of protein in the urine in 24 hours. If protein loss exceeds 300 mg in 24 hours, this is considered proteinuria. Urine dipstick analysis for protein measures only a single point in time and does not necessarily reflect protein loss over 24 hours. Nonetheless, the following conversion can be made, assuming average urine production of about a liter a day, and consistent loss throughout the 24 hour period: ResultNeg.Trace1+2+3+4+Dipstick (mg/dl)<1515-2930100300>200024 Hour (mg)<150150-299 mg30010003 g>20 g Some but not all women with toxemia demonstrate fluid retention (as evidenced by edema or sudden weight gain exceeding 2 pounds per week). Some but not all women with toxemia will demonstrate increased reflexes (clonus). Pre-eclampsia Toxemia of pregnancy is subdivided into two categories: pre-eclampsia and eclampsia. The difference is the presence of seizures in women with eclampsia. The clinical course of pre-eclampsia is variable. Some women demonstrate a mild, stable course of the disease, with modest elevations of blood pressure and no other symptoms (mild pre-eclampsia). Others display a more aggressive disease, with deterioration of both maternal and fetal condition (severe pre-eclampsia). Some of the points of differentiation are listed here. Notice that there is no "moderate" pre-eclampsia, only mild and severe.
PRIVATEProblemMild Pre-EclampsiaSevere Pre-EclampsiaBlood Pressure>140/90>160/110Proteinuria1+ (300 mg/24 hours)2+ (1000 mg/24 hours)Edema+/-+/-Increased reflexes+/-+Upper abdominal pain-+Headache-+Visual Disturbance-+Decreased Urine Output-+Elevation of Liver Enzymes-+Decreased Platelets-+Increased Bilirubin-+Elevated Creatinine-+
The definitive treatment of pre-eclampsia is delivery. The urgency of delivery depends on the gestational age and the severity of the disease. Severe pre-eclampsia usually requires urgent delivery (within hours) more or less regardless of gestational age. In this situation, the risk of serious complications (placental abruption, growth restriction, liver failure, renal failure, hemorrhage, coagulopathy, seizures, and death) will generally take precedence over the fetal benefit of prolonging the pregnancy. Induction of labor is preferred, unless the maternal condition is so tenuous and the cervix so unfavorable that cesarean section is warranted. In milder cases, particularly if remote from term or with an unfavorable cervix, treatment may range from hospitalization with close observation to initial stabilization followed by induction of labor following preparation of the cervix over the course of several days. In the most mild, selected cases, outpatient management might be considered with careful monitoring of maternal and fetal condition. Traditionally, magnesium sulfate has been used to treat pre-eclampsia. Magnesium sulfate, in high enough doses, is a reasonably effective anti-convulsant, mild anti-hypertensive and mild diuretic. While other agents may be more potent in each of these individual areas, none combines all three of these features into a single drug. The world's experience with magnesium sulfate to treat pre-eclampsia is extensive and these unique features provide considerable reassurance in employing it in these clinical settings. Magnesium sulfate is given IM, IV or both. All are effective reasonably effective in preventing seizures. Because the risk of eclampsia continues after delivery, MgSO4 is frequently continued for 24 to 48 hours after delivery. Magnesium sulfate 10 gm in a 50% solution, one-half (5 gm) IM, injected deeply into each upper outer buttock quadrant. Every 4 hours thereafter, Magnesium sulfate 5 gm IM is injected into alternating buttocks. Repeat injections are postponed if patellar reflexes are absent. Because these injections are painful, 1 ml of 2% Xylocaine is sometimes added to the magnesium. This schedule gives therapeutic levels of magnesium (4-7 meq/L) Because IM magnesium sulfate does not initially achieve its therapeutic levels for 30 to 45 minutes, in cases of severe pre-eclampsia, an IV bolus of magnesium sulfate can be added. 4 gm magnesium sulfate as a 20% solution can be given slowly over at least 5 minutes, followed by the IM injections described above. Magnesium sulfate 4 gm IV, slowly, over at least 5 minutes, followed by 2 gm IV/hour. The therapeutic margin (distance between effective dose and toxicity) is relatively thin with magnesium sulfate, so some precautions need to be taken to prevent overdose. The biggest problem with MgSO4 is respiratory depression (10 meq/L) and respiratory arrest (>12 meq/L). Cardiovascular collapse occurs at levels exceeding 25 meq/L. MgSO4 levels can be measured in a hospital setting, but clinical management works about as well and is non-invasive. The patellar reflexes (knee-jerk) disappear as magnesium levels rise above 10 meq/L. Periodic checking of the patellar reflexes and withholding MgSO4 if reflexes are absent will usually keep your patient away from respiratory arrest. This is particularly important if renal function is impaired (as it often is in severe pre-eclampsia) since magnesium is cleared entirely by the kidneys. In the case of respiratory arrest or severe respiratory depression, the effects of MgSO4 can be reversed by the administration of calcium. Calcium Gluconate (Ca++) 1 gm IV push. If BP is persistently greater than 160/110, administer an antihypertensive agent to lower the BP to levels closer to 140/90. One commonly-used agent for this purpose is: Hydralazine 5-10 mg IV every 15-20 minutes. Don't drop the pressure too far (below a diastolic of 90) as uterine perfusion may be compromised. Eclampsia Eclampsia means that maternal seizures have occurred in association with toxemia of pregnancy. These tonic/clonic episodes last for several minutes and may result in bite lacerations of the tongue. During the convulsion, maternal respirations stop and the patient turns blue because of the desaturated hemoglobin in her bloodstream. As the attack ends, she gradually resumes breathing and her color returns. Typically, she will remain comatose for varying lengths of time. If convulsions are frequent, she will remain comatose throughout. If infrequent, she may become arousable between attacks. If untreated, convulsions may become more frequent, followed by maternal death. In more favorable circumstances, recovery occurs. Eclampsia should be aggressively treated with magnesium sulfate (described above), followed by prompt delivery, often requiring a cesarean section. If convulsions persist despite MgSO4, consider: Valium 10 mg IV push HELLP Syndrome The HELLP Syndrome is characterized by: Hemolysis Elevated Liver Enzymes Low Platelets This serious condition is associated with severe pre-eclampsia and the treatment is similar...delivery with prophylaxis against maternal seizures. Unlike pre-eclampsia, patients with HELLP syndrome may continue to experience clinical problems for days to weeks or even months. If the HELLP syndrome is mild, it may gradually resolve spontaneously, but more severe forms often require intensive, prolonged care to achieve a favorable outcome. Normal Labor and Delivery Labor Labor consists of regular, frequent, uterine contractions which lead to progressive dilatation of the cervix. The diagnosis of labor may not be obvious for several reasons: Braxton-Hicks contractions are uterine contractions occurring prior to the onset of labor. They are normal and can be demonstrated with fetal monitoring techniques early in the middle trimester of pregnancy. These innocent contractions can be painful, regular, and frequent, although they usually are not. While the uterine contractions of labor are usually painful, they are sometimes only mildly painful, particularly in the early stages of labor. Occasionally, they are painless. Cervical dilatation alone does not confirm labor, since many women will demonstrate some dilatation (1-3 cm) for weeks or months prior to the onset of true labor. Thus, in other than obvious circumstances, labor will usually be determined by observing the patient over time and demonstrating progressive cervical changes, in the presence of regular, frequent, painful uterine contractions. The cause of labor is not known but may include both maternal and fetal factors. Latent Phase Labor The first stage of labor is that portion leading up to complete dilatation. The first stage can be divided functionally into two phases: the latent phase and the active phase. Latent phase labor (also known as prodromal labor) precedes the active phase of labor. Women in latent phase labor: Are less than 4 cm dilated. Have regular, frequent contractions that may or may not be painful. May find their contractions wax and wane Dilate only very slowly Can usually talk or laugh during their contractions May find this phase of labor lasting days or longer. Active Phase Labor Active phase labor is a time of rapid change in cervical dilatation, effacement, and station. Active phase labor lasts until the cervix is completely dilated. Women in active phase labor: Are at least 4 cm dilated. Have regular, frequent contractions that are usually moderately painful. Demonstrate progressive cervical dilatation of at least 1.2-1.5 cm per hour. Usually are not comfortable with talking or laughing during their contractions  Progress of Labor For a woman experiencing her first baby, labor usually lasts about 12-14 hours. If she has delivered a baby in the past, labor is generally quicker, lasting about 6-8 hours. These averages are only approximate, and there is considerable variation from one woman to the next, and from one labor to the next. During labor, the cervix dilates (opens) and effaces (thins). This process has been likened to the process of pulling a turtleneck sweater over your head. The collar opens (dilates) to allow your head to pass through, and also thins (effaces) as your head passes through. The process of dilatation and effacement occurs for both mechanical reasons and biochemical reasons. The force of the contracting uterus naturally seeks to dilate and thin the cervix. However, for the cervix to be able to respond to these forces requires it to be "ready." The process of readying the cervix on a cellular level usually takes place over days to weeks preceding the onset of labor. Descent means that the fetal head descends through the birth canal. The "station" of the fetal head describes how far it has descended through the birth canal. This station is determined relative to the maternal ischial spines, bony prominences on each side of the maternal pelvic sidewalls. "0 Station" ("Zero Station") means that the top of the fetal head has descended through the birth canal just to the level of the maternal ischial spines. This usually means that the fetal head is "fully" engaged (or "completely engaged"), because the widest portion of the fetal head has entered the opening of the birth canal (the pelvic inlet). If the fetal head has not reached the ischial spines, negative numbers, such as -2 (meaning the top of the fetal head is still 2 cm above the ischial spines) indicates this. If the fetal head has descended further than the ischial spines, positive numbers, such as +2 (meaning the top of the head is now 2 cm below the ischial spines) indicates this. Negative numbers above -3 indicate the fetal head is unengaged (floating). Positive numbers beyond +3 (such as +4 or +5) indicate that the fetal head is crowning and about to deliver. Women having their first baby often demonstrate deep engagement (0 or +1) for days to weeks prior to the onset of labor. Women having their second or third baby may not engage below -2 or -3 until they are in labor, and nearly completely dilated. Delivery of the Baby Delivery is also known as the second stage of labor. It begins with complete dilatation and ends when the baby is completely out of the mother. The exact time of delivery is normally taken at the moment the baby's anterior shoulder (the shoulder delivering closest to the mother's pubic bone) is out. As the fetal head passes through the birth canal, it normally demonstrates, in sequence, the "cardinal movements of labor." These include: Engagement (fetal head reaches 0 station.) Descent (fetal head descends past 0 station.) Flexion (head is flexed with the chin to its' chest.) Internal Rotation (head rotates from occiput transverse to occiput anterior.) Extension (head extends with crowning, passing through the vulva.) External Rotation (head returns to its' occiput transverse orientation) Expulsion (shoulders and torso of the baby are delivered.) As the fetal head descends below 0 station, the mother will perceive a sensation of pressure in the rectal area, similar to the sensation of an imminent bowel movement. At this time she will feel the urge to bear down, holding her breath and performing a valsalva, to try to expel the baby. This is called "pushing." The maternal pushing efforts assist in speeding the delivery. For women having their first baby, the second stage will typically take an hour or two. Delivery of the Placenta Immediately after delivery of the baby, the placenta is still attached inside the uterus. Some time after delivery, the placenta will detach from the uterus and then be expelled. This process is called the "3rd stage of labor" and may take just a few minutes or as long as an hour. Signs that the placenta is beginning to separate include: A sudden gush of blood Lengthening of the visible portion of the umbilical cord. The uterus, which is usually soft and flat immediately after delivery, becomes round and firm. The uterus, the top of which is usually about half-way between the pubic bone and the umbilicus, seems to enlarge and approach the umbilicus. Immediately after the delivery of the baby, uterine contractions stop and labor pains go away. As the placenta separates, the woman will again feel painful uterine cramps. As the placenta descends through the birth canal, she will again feel the urge to bear down and will push out the placenta. Managing Labor and Delivery Most labors and deliveries are safe, spontaneous processes, requiring little or no intervention, and result in a healthy mother and healthy baby. Some are not so safe and may not have the same good outcome. The two purposes of L&D management are: Monitoring the mother and baby for abnormalities which, through detection and treatment, will lead to a happy outcome for both. Applying knowledge and skills to improve on the quality of the experience or outcome which nature would otherwise provide. This would include such areas as pain relief, prevention or repair of lacerations, reducing fatigue, anemia, risk of infection, and injury to the mother and baby. Initial Evaluation An initial evaluation is performed to: Evaluate the current health status of the mother and baby, Identify risk factors which could influence the course or management of labor, and Determine the labor status of the mother. History Interview the patient as soon as she arrives. Certain key questions will provide considerable insight into the patient's pregnancy and current status: What brought you in to see me? Are you contracting? When did they start? Are you having any pain? Are you leaking any fluid or blood? When did that begin? Have there been any problems with your pregnancy? Has the baby been moving normally? When did you last eat? What did you have? Are you allergic to any medication? Do you normally take any medication? Have you ever been hospitalized for any reason? Risk Factors For some women, there is a greater chance of problems during labor than for other women. Various factors have been identified to try to predict those women who will experience problems and those who will not. These are called risk factors. Some are more significant than others. While most women with any of these factors will experience good outcomes, they may benefit from increased surveillance or additional resources. PRIVATEThe following are associated with a moderate increase in risk: Age < 16 or > 35 2 spontaneous or induced abortions < 8th grade education > 5 deliveries Abnormal presentation Active TB Anemia (Hgb <10, Hct <30%) Chronic pulmonary disease Cigarette smoking Endocrinopathy Epilepsy Heart disease class I or II Infertility Infants > 4,000 gm Isoimmunization (ABO) Multiple pregnancy (at term) Poor weight gain Post-term pregnancy Pregnancy without family support Preterm labor (34-37 weeks) Previous hemorrhage Previous pre-eclampsia Previous preterm or SGA infant Pyelonephritis Rh negative Second pregnancy in 9 months Small pelvis Thrombophlebitis Uterine scar or malformation Venereal disease These are associated with a higher increase in risk: Age >40 Bleeding in the 2nd or 3rd TM Diabetes Chronic renal disease Congenital anomaly Fetal growth retardation Heart disease class III or IV Hemoglobinopathy Herpes Hypertension Incompetent cervix Isoimmunization (Rh) Multiple pregnancy (pre-term) > 2 spontaneous abortions Polyhydramnios Premature rupture of membranes Pre-term labor (<34 weeks) Prior perinatal death Prior neurologically damaged infant Severe pre-eclampsia Significant social problems Substance abuse  Vital Signs Obtain a set of vital signs from the mother, including BP, pulse and temperature. Elevated BP suggests the presence of pre-eclampsia. Elevated temperature suggests the possible presence of infection. While a pregnant pulse of up to 100 BPM or greater may be normal, rapid pulse may also indicate hypovolemia. Contractions Check the frequency and duration of any uterine contractions. In some cases, the patient will have been timing the contractions. Placing your hand on the maternal abdomen, you will be able to feel each contraction as the normally soft uterus becomes firm and rises out of the abdomen. Time the contractions from the beginning of one to the beginning of the next one. Also note the duration of the contractions and their relative intensity (mild, mild-to-moderate, moderate, severe) Fetal Heart Rate Record the fetal heart rate. This can be done with a fetal Doppler device, and electronic fetal monitor, ultrasound visualization of the fetal heart, or a DeLee type stethoscope. Normal rates are between 120 and 160 BPM at full term. Post term babies may sometimes normally have rates as low as 110 BPM. Urine for Protein and Glucose Check the urine for protein and glucose. The presence of protein (1+ or greater) can suggest the presence of pre-eclampsia. The presence of glucosuria (1+ to 2+ or greater) can suggest the presence of diabetes. Estimated Fetal Weight An average baby at full term weighs 7 to 7 1/2 pounds. By feeling the maternal abdomen, an experienced examiner can often predict within a pound the actual birthweight. A woman who has delivered a baby in the past can often do about as well in predicting her current baby's weight if you ask her, "Is this baby bigger or smaller than your last?" Dilatation and Effacement Using sterile gloves and lubricant, perform a vaginal exam and determine the dilatation and effacement of the cervix. A small amount of bleeding during the days or hours leading up to the onset of labor is common and called "bloody show." Dilatation is expressed in centimeters. I have relatively large fingers, and for my hands, I make the following generalizations: 1.5 cm: One finger fits tightly through the cervix and touches the fetal head. 2.0 cm: One finger fits loosely inside the cervix, but I can't fit two finger in. 3.0 cm: Two fingers fit tightly inside the cervix. 4.0 cm: Two fingers fit loosely inside the cervix. 6.0 cm: There is still 2 cm of cervix still palpable on both sides of the cervix. 8.0 cm: There is only 1 cm of cervix still palpable on both sides of the cervix. 9.0 cm: Not even 1 cm of cervix is left laterally, or there is only an anterior lip of cervix. 10.0 cm: I can't feel any cervix anywhere around the fetal head. Effacement is easiest to measure in terms of centimeters of thickness, ie., 1 cm thick, 1.5 cm thick, etc. Alternatively, you may express the thickness in percent of an uneffaced cervix...ie, 50%, 90%, etc. This expression presumes a good knowledge of what an uneffaced cervix should feel like. Fetal Orientation By abdominal and pelvic examination, determine the orientation of the fetus. There are basically 3 alternatives: Cephalic (head first, or vertex) Breech (butt or feet coming first) Transverse lie (side-to-side orientation, with the fetal head on one side and the butt on the other) Most of the time, the fetus will be head first (vertex). The easiest way for a relatively inexperienced examiner to determine this presentation is by pelvic exam. The fetal head is hard and bony, while the fetal butt is soft everywhere except right over the fetal pelvic bones. When the baby is presenting butt first, the presenting part is very soft, but with hard areas within it (sacrum and ischial tuberosities). If one or both feet are presenting first, you will feel them. If you don't feel any presenting part (head or butt) on pelvic exam, there is a good chance the baby is in transverse lie (or oblique lie). Then things get a little more complicated. Transverse lie or oblique lie can be suspected if the fundal height measurement is less than expected and if on abdominal exam, the basic orientation of the fetus is side-to-side. More experienced examiners can tell much from an abdominal exam. Making a "V" with their thumb and index finger and pressing down just above the pubic bone, they can usually feel the hard fetal head at the pelvic inlet. Leopold's Maneuvers Leopolds' maneuvers are used to determine the orientation of the fetus through abdominal palpation. 1. Using two hands and compressing the maternal abdomen, a sense of fetal direction is obtained (vertical or transverse). 2. The sides of the uterus are palpated to determine the position of the fetal back and small parts. 3. The presenting part (head or butt) is palpated above the symphysis and degree of engagement determined. 4. The fetal occipital prominence is determined. Status of Fetal Membranes With a pelvic examination, determine the status of the fetal membranes (intact or ruptured). A history of a sudden gush of fluid is suggestive, but not convincing evidence of ruptured membranes. Sudden, involuntary loss of urine is a common event in late pregnancy. Usually, ruptured membranes are confirmed by a continuing, steady leakage of amniotic fluid, pooling of clear, and Nitrazine positive fluid in the vagina on speculum exam. Vaginal secretions are normally slightly acid, turning Nitrazine paper yellow. Amniotic fluid, in contrast, is a weak base, and will turn the Nitrazine paper a dark blue. Dried amniotic fluid forms crystals (ferning) on a microscope slide. Vaginal secretions do not. Blood Count Following admission, the hemoglobin or hematocrit may be useful. Women with significant anemia are more likely to have problems sustaining adequate uterine perfusion during labor. They also have less tolerance for hemorrhage than those with normal blood counts. Women with no prenatal care should, in addition, have a blood type, Rh factor, and atypical antibody screen performed. Other tests may be indicated, based on individual histories. Management of Early Labor If the patient is in early labor, with a normal pregnancy, and intact membranes, she may feel like ambulating and this is very acceptable. Not all women in early labor feel like walking and she need not be forced out of bed. Some patients, particularly those with ruptured membranes and those with certain risk factors are probably better off staying in bed, even during early labor. While in bed, it is preferable, in women without continuous electronic fetal monitoring, to have them lie on one side or the other, but to avoid being on their back. Such lateral positioning maximizes uterine blood flow and provides a greater margin of safety for the baby. Women with continuous electronic fetal monitoring may choose whatever position is most comfortable. If there is a problem with uterine blood flow, it will be demonstrated on the fetal monitoring strip and appropriate position changes can be undertaken. Recheck the maternal vital signs every 4 hours. Elevation of blood pressure may indicate the onset of pre-eclampsia. Elevation of temperature >100.4 may indicate the development of infection. Because of the risk of vomiting and aspirating later in labor, it is best to avoid oral intake other than small sips of clear liquids or ice chips. If labor is lengthy or dehydration becomes an issue, IV fluids are administered. Lactated Ringer's or Lactated Ringer's with 5% Dextrose at 125 cc/hour (6-hours for 1 L) are good choices. Periodic pelvic exams are performed using sterile gloves and a water-soluble lubricant. The frequency of such exams is determined by individual circumstances, but for a normal patient in active labor, an exam every 2-4 hours is common. In active labor, progress of at least 1 cm per hour is the expected pattern. If the patient feels rectal pressure, an exam is appropriate to see if she is completely dilated. Some women experience difficulty emptying their bladder during labor. Avoiding overdistension of the bladder during labor will help prevent postpartum urinary retention. If the patient is uncomfortable with bladder pressure and unable to void spontaneously, catheterization will be welcomed. Monitor the Fetal Heart Prior to active labor, the fetal heart rate for low risk patients is usually evaluated every hour or two. Once active labor begins for these women (4 cm dilated, with regular, frequent contractions), the fetal heart rate is evaluated every 30 minutes. This can be done by looking at the electronic fetal monitor (if used), or by measuring the fetal heart rate following a contraction. Fetal jeopardy is likely if the auscultated fetal heart rate is less than 100 BPM, even if it later rises back to the normal range of 120-160. Persistent fetal tachycardia (greater than 160 BPM) is also of concern. For women with significantly increased risks, it is better to evaluate the fetal heart rate every 15 minutes during the active phase of labor. Women in the second stage of labor (completely dilated but not yet delivered) usually have their fetal heart rate evaluated every 5 minutes until delivery. Electronic Fetal Monitors Electronic fetal monitors continuously record the instantaneous fetal heart rate on the upper channel and uterine contractions on the lower channel. They do this by attaching, either externally (and non-invasively) or internally, to detect the fetal heart and each uterine contraction. A normal contraction pattern in active labor shows contractions occurring about every 2-3 minutes and lasting about 60 seconds. The normal fetal heart rate baseline is 120-160 BPM and has both short and long-term "variability." Short term variability means that from one moment to the next, the fetal heart speeds up slightly and then slows down slightly, usually with a range of 3-5 BPM from the baseline. Reduced variability occurs normally during fetal sleep and usually returns after 20 to 40 minutes. It also may be present with fetal anomalies or injury. Persistent or progressively reduced variability is not, by itself, a sign of fetal jeopardy. But in combination with other abnormalities (see below), it may indicate fetal intolerance of labor. Long-term variability represents broad-based swings in fetal heart rate, or "waviness," occurring up to several times a minute. One form of long-term variability of particular significance is a fetal heart "acceleration." These usually occur in response to fetal movement, and are 15 BPM above the baseline or more, lasting 10-20 seconds or longer. They can often be provoked by stimulating the fetal scalp during a pelvic examination, or by acoustically stimulating the fetus with a loud, obnoxious noise. The presence of fetal accelerations is reassuring that the fetus is healthy and tolerating the intrauterine environment well. During labor, no significance is attached to the absence of fetal accelerations. Tachycardia is the sustained elevation of fetal heart rate baseline above a 160 BPM. Most tachycardias are not indicative of fetal jeopardy. Causes include: PRIVATEMaternal fever Chorioamnionitis Maternal hypothyroidism Drugs (tocolytics, Vistaril, etc.) Fetal hypoxia Fetal anemia Fetal heart failure Fetal arrhythmias Bradycardia is the sustained depression of fetal heart rate baseline below 120 BPM. Most of these are caused by increased vagal tone, although congenital cardiac abnormalities can also be responsible. Mild bradycardia (to 80 or 90 BPM) with retention of beat-to-beat variability is common during the second stage of labor and not of great concern so long as delivery occurs relatively soon. Moderate to severe bradycardia (below 80 BPM) with loss of beat-to-beat variability, particularly in association with late decelerations, is more troubling and may indicate fetal distress, requiring prompt resolution. Early decelerations are periodic slowing of the fetal heartbeat, synchronized exactly with the contractions. These dips are rarely more than 20 or 30 BPM below the baseline. These innocent changes are thought to be due, in many cases, to fetal head compression within the birth canal. Variable decelerations are variable in onset, duration and depth. They may occur with contractions or between contractions. Typically, they have an abrupt onset and rapid recovery (in contrast to other types of decelerations which gradually slow and gradually recover. Variable decelerations are thought to represent a vagal response to some degree of umbilical cord compression. They are not caused by hypoxia, although if severe enough, frequent enough and persistent enough, can ultimately lead to some degree of fetal acidosis. Mild or moderate variable decelerations are common and not considered threatening. Mild variable decelerations do not dip below 70 BPM and last less than 30 seconds. Severe variable decelerations dip below 60 BPM for at least 60 seconds ("60 x 60"). If persistent and not correctable by simple means, they can be threatening to fetal well-being. Late decelerations are repetitive, gradual slowing of the fetal heartbeat toward the end of the contraction cycle. They are felt to represent some degree of utero-placental insufficiency. If persistent and not correctable, they represent a threat to fetal well-being. Prolonged decelerations last more than 60 seconds and occur in isolation. Causes include maternal supine hypotension, epidural anesthesia, paracervical block, tetanic contractions, and umbilical cord prolapse. Some of these are largely self-correcting, such as the deceleration following paracervical block, while others (maternal supine hypotension) respond to simple measures such as repositioning. Other causes (such as umbilical cord prolapse) require prompt intervention to avoid or reduce the risk of fetal injury. Pain Relief Various cultures approach the pain of labor differently and individuals vary in their responses to labor pains. Some women will need little or no help with pain relief, while others will benefit from it. While no analgesic is 100% safe 100% of the time, pain relief is generally very safe and provides for a much happier experience for the woman and her family. The following principles may be helpful: A small number of women in labor will have virtually no pain and they do not need any analgesia. The majority of women will have moderate discomfort, particularly toward the end of labor and they will generally appreciate some analgesia. Some women will experience severe pain during labor and they will benefit from your most intensive efforts. Giving analgesics prior to the onset of active labor (before 4 cm dilatation) will usually slow the labor process, although for some (those with a prolonged latent phase), it may actually speed up labor. Focused breathing (Lamaze techniques) during contractions can be very helpful in reducing or eliminating the need for pharmacologic analgesia. Hypnotherapy can provide similar relief, as can massage therapy. Narcotic analgesics can be highly effective at treating the pain of labor. They are generally safe for the baby, although it is better to avoid large doses toward the end of labor in order to avoid respiratory depression in the newborn. The greatest safety with narcotics is achieved when an antagonist (naloxone or Narcan) is available to treat the baby should depression appear. Good dosages for this purpose include: Dilaudid (butorphanol) 1-2 mg IM Q 3-4 hours Dilaudid (butorphanol) 1 mg IM and 1 mg IV every 3-4 hours Demerol (meperidine) 12-25 mg IV every 60-90 minutes Demerol (meperidine) 50-100 mg IM every 3-4 hours Demerol (meperidine) 50 mg plus Vistaril (promethazine) 50 mg IM every 3-4 hours Morphine 2.5-5 mg IV every 60-90 minutes Morphine 7.5 - 15 mg IM every 3-4 hours More frequent, smaller doses are better than larger, less-frequent doses. Smaller doses given IV are immediately effective, but wear off quickly. Whether that is an advantage or disadvantage depends on how close the woman is to delivery and her need for immediate pain relief. Paracervical blocks (up to 20 cc of 1% Lidocaine in divided doses) can stop the pain of contractions for up to an hour and a half. Care must be taken to prevent excessive fetal uptake of the Lidocaine, which can lead to fetal bradycardia. Continuous lumbar epidural anesthetic is effective and versatile, but requires skilled providers. In some settings, this can be very appropriate, but in other operational settings, these resources may not be available. Inhalation of 50% nitrous oxide with 50% oxygen, can give very effective pain relief during labor and is safe for the mother and baby. It is safest when self-administered by the mother, under the guidance of her birth attendant. If she feels dizzy or starts to achieve anesthetic levels of the nitrous, she will naturally release the mask, reversing the effects of the nitrous oxide. Less commonly used is a self-administered volatilized gas of methoxyflurane. It is capable of achieving anesthetic levels and so must be very closely monitored. Second Stage Labor On reaching complete cervical dilatation, the woman has entered the second stage of labor. The second stage lasts until the delivery of the baby. During the second stage, try to measure the fetal heart rate every 5 minutes. During the second stage of labor, the woman will feel the uncontrollable urge to bear down. This valsalva has the effect of increasing the expulsive forces and speeding the delivery process. For most women, the most effective way to push is in the semi-recumbent position. With the onset of a contraction, she takes several, rapid, deep breaths. Then she holds her breath and tightens her stomach muscles, as though she were trying to move her bowels. She pushes for 10 seconds, relaxes, takes another breath, and pushes for another 10 seconds. Most women can get three or four pushes into a single contraction. She will usually push more effectively if her knees are pulled back towards her shoulders. Some women find they are not comfortable in the semi-reclining position and they may push while tilted toward one side or the other. Some women prefer to deliver on their side, with one knee drawn up and the other leg straightened (the Sims position). Some women prefer to deliver in the sitting or squatting position. Duration of the second stage is typically an hour or two for a woman having her first baby. For a woman having a subsequent baby, the second stage is usually shorter, less than an hour. Preparing for the Delivery Ideally, you will have a sterile field (sterile towels, drapes, and equipment), but a clean field is nearly as good. Preparation of the vulva with antiseptic solution, shaving of pubic hairs and evacuating the bowels with an enema is not generally necessary, but might be a good idea in selected operational settings where contamination may be significant. For an uncomplicated delivery, you will need: Latex gloves Two baby blankets (one to initially receive and dry the baby and the other for after the baby is dried). Something to clamp the umbilical cord (2 hemostats, 2 shoestrings, 2 ligatures, 2 parachute cords, etc.). Something to cut the umbilical cord (scissors, scalpel, K-Bar, pocket knife, etc.) Something to suction the baby's nose and mouth (bulb syringe, suction tubing, DeLee Trap, etc.) Something in which to place the placenta (basin, bowel, mess kit, etc.) Something to wipe up and absorb blood from the field (4x4 gauze sponges, sanitary pads, towels, small or medium battle dressings, etc.) Injectable Lidocaine (for the delivery or repair of lacerations) Suture (2-0 or 3-0 chromic, plain, or synthetic absorbable) for repair of any lacerations Delivery During the delivery, the fetal head emerges through the vaginal opening, usually facing toward the woman's rectum. As the fetal head delivers, support the perineum to reduce the risk of perineal laceration from uncontrolled, rapid delivery. After the fetal head delivers, allow time for the fetal shoulders to rotate and descend through the birth canal. This pause also allows the birth canal to squeeze the fetal chest, forcing amniotic fluid out of the baby's nose and mouth. After a reasonable pause (15-30 seconds), have the woman bear down again, delivering the shoulders and torso of the baby. Episiotomy Sometimes, a small incision is made in the perineum to widen the vaginal opening, reduce the risk of laceration, and speed the delivery.  There are two forms, midline and mediolateral. A midline episiotomy is safe, and avoids major blood vessels and nerves. It heals well and quickly and is reasonably comfortable after delivery. If the fetal head is still too big to allow for delivery without tearing, the lacerations will likely extend along the line of the episiotomy. Lacerations through the rectal sphincter and into the rectum are relatively common with this type of episiotomy. A mediolateral episiotomy avoids the problems of tearing into the rectum by directing the forces laterally. However, these episiotomies bleed more, take longer to heal, and are generally more uncomfortable after delivery. In an operational setting, the major question is not so much where to put the episiotomy, but whether to perform this procedure at all. If you don't perform an episiotomy, you are increasing the risk of vulvar lacerations, but these are usually (not always) small, non-threatening lacerations that will heal well without further complications. If you perform a midline episiotomy, you will have fewer vulvar lacerations, but the few you have are more likely to be the trickier 3rd and 4th degree lacerations involving the anal sphincter and rectum. If you perform a mediolateral episiotomy, you will avoid the 3rd and 4th degree lacerations, but you may open the ischio-rectal fossa to contamination and infection and increase the intrapartum The best approach is an individualized one, that takes into account your own training and expertise, the clinical circumstances, and the operational circumstances. Anesthesia Although the perineum of a full-term patient is stretchy and compliant, the passage of a baby through the birth canal and vulva is usually uncomfortable. In a hospital setting, anesthesia for the delivery might consist of: Local infiltration Pudendal block Epidural Spinal (saddle block) General anesthetic In many operational settings, the only available anesthesia for delivery will be local infiltration. Use 1% Lidocaine and inject just beneath the skin. Don't inject into the deeper tissues because there are no significant numbers of nerves there. Use 10-20 cc total. The maximum dose of Lidocaine you can give at any one time to avoid Lidocaine toxicity is 50 cc of 1% Lidocaine. Try not to use the whole 50 cc for the delivery as you may need more for the repair of any lacerations. Clamp and Cut the Cord After the baby is born, leave the umbilical cord alone until the baby is dried, breathing well and starts to pink up. During this time, keep the baby more or less level with the placenta still inside the mother. Once the baby is breathing, put two clamps on the umbilical cord, about an inch (3 cm) from the baby's abdomen. Use scissors to cut between the clamps. If you don't have clamps and scissors, use anything available to accomplish the same purpose. In this example, the radio-opaque threads from a 4 x 4 gauze pad have been removed and used to tie the cord before cutting it with a pocket knife. The Placenta Anywhere from a few minutes after delivery to an hour later, the placenta will separate and deliver. While you are awaiting delivery of the placenta, don't pull on the cord or massage the uterus to try and make it deliver more quickly. Pulling to vigorously on the cord, in the right clinical setting, may lead uterine inversion (the uterus turns inside out), a very serious and dangerous complication. Massaging the uterus often only causes uncoordinated contractions which slow a clean shearing of the placenta. As the placenta detaches and descends through the birth canal, the woman will again feel contractions and the urge to bear down. As she does this, the placenta will be expelled. Make sure all the fetal membranes come out with the placenta. Inspect the placenta for completeness. If a portion is missing, she will need to have her uterus explored and the missing piece removed. Also inspect the cord to make sure there are 3 blood vessels present (2 arteries and 1 vein). Two-vessel cords are associated with certain congenital anomalies. Uterine Massage After delivery of the placenta, the uterus normally contracts firmly, closing off the open blood vessels which previously supplied the placenta. Without this contraction, rapid blood loss would likely prove very problematic or worse. To encourage the uterus to firmly contract, oxytocin 10 mIU IM can be given after delivery. Alternatively, oxytocin 10 or 20 units in a liter of IV fluids can be run briskly (150 cc/hour) into a vein. Breast feeding the baby or providing nipple stimulation (rolling the nipple between thumb and forefinger) will cause the mother's pituitary gland to release oxytocin internally, causing similar, but usually milder effects. A simple way to encourage firm uterine contraction is with uterine massage. The fundus of the uterus (top portion) is vigorously massaged to keep it the consistency of a tightened thigh muscle. If it is flabby, the patient will likely continue to bleed. Post Partum Care Lochia is the name for vaginal discharge following delivery. For several days, vaginal bleeding will persist, similar to a heavy menstrual period (lochia rubra). Then, it will thin and become more pale in color (lochia serosa). By the 10th day, it will take on a white or yellow appearance due to the admixture of white blood cells (lochia alba). If it has a foul smell at any time, the odor suggests the presence of infection. Maternal temperature should be periodically assessed. Any persistent fever (>100.4 twice over at least 6 hours) indicates the possibility of infection and should be investigated. Blood pressure should also be checked several times during the first day and periodically thereafter. Abnormally high blood pressure can indicate late-onset pre-eclampsia. Low blood pressure may indicate hypovolemia. For the first several days after delivery, the breasts produce a clear, yellow liquid known as colostrum. For nursing mothers, colostrum provides some nutrition and significant antibodies to their babies. Then, the breasts will swell (engorge) with milk, white in color, and containing more calories (fat) and volume. The initial engorgement can be uncomfortable. Nursing relieves this discomfort. For women not breast-feeding, firm support of the breasts and ice packs will help relieve the discomfort, which will disappear within a few days in any event. Nipples should be kept clean and dry. It is important to establish bladder function early in the post partum phase. Because bladder distention due to post partum bladder atony or urethral obstruction is common, encourage the woman to void early and often. Any evidence of significant urinary retention should be treated with catheterization and prompt resolution is expected. When cleansing the vulva, avoid rectal contamination of the vagina or urethra. Aftercramps are common, crampy pains originating in the uterus. They are less common among first-time mothers, and more common when nursing. They are annoying but not dangerous and will usually disappear within a few days. Oral analgesics, such as acetaminophen with codeine, or ibuprofen are appropriate and will ease the pain of vulvar lacerations, aftercramps, and the various muscle aches related to a physically demanding labor and delivery. Rarely will these medications need to be continued beyond the first few days. Swelling of the hands, ankles and face in the first few days following delivery is common, particularly if IV fluid have been given. In the absence of other indicators of pre-eclampsia (elevated blood pressure and proteinuria), it is of no clinical significance, but may be distressing to the patient. Reassure the patient that this is a normal, expected event and will resolve spontaneously. Rh negative women who deliver Rh positive babies should receive an injection of Rh immune globulin (Rhogam) to prevent Rh sensitization in later pregnancies. This is best done within 3 days of delivery. In operational settings where the Rh type of the infant is not known, it is safe to give Rhogam to all Rh negative women following delivery. Those with Rh positive babies will benefit and those with Rh negative babies will not be harmed. After delivery, the mother needs time to rest, sleep, and regain her strength. She may eat whatever appeals to her and can get up and move around whenever she would like. Prolonged bedrest is neither necessary nor desirable. There are a few cautionary notes: While she may be up walking, strenuous physical activity will increase her bleeding and is not a good idea. The first time she gets up, someone should be with her to assist in getting her back down if she feels light-headed. She may shower or bathe freely, but prolonged standing in a hot shower may lead to dizziness, in this setting of borderline hypovolemia and vasodilatation. After 3 weeks, the uterine lining is normally completely healed and a new endometrium regenerated. At this point, most normal activities can be resumed, although strenuous physical activity is usually restricted until after 6 weeks. In normal circumstances, women can resume sexual activities whenever they feel like it. Most women won't feel like it for a while, and perineal lacerations generally take 4-6 weeks to completely heal. Even then, intercourse may be uncomfortable, due to residual irritation around any laceration sites, vaginal dryness due to the natural estrogen suppression after delivery, or psychological factors surrounding resumption of intercourse. Patients can be reassured that this is common, temporary, and very much improved with the use of water-soluble lubricants, such as KY Jelly or Surgilube. Oral contraceptive pills, if desired, can be started any time during the first few days post partum and are compatible with breast feeding. Alternatively, their use may be postponed until the 6-week examination, a common time for follow-up care. Problems During Labor and Delivery Preterm Labor Most labors occur within 2 weeks of the due date. Labor occurring prior to the 38th week of pregnancy is preterm labor, although definitions vary depending on the clinical circumstances. While delivering a little bit early usually poses no particular problem for the mother or the baby, more significant amounts of prematurity pose more significant risks for the infant. Of these, immaturity of the respiratory tree is among the most hazardous, but other organs can also be a problem. The cause of preterm labor is unknown, but in about half the cases, it is associated with detectable intrauterine infection. Another significant number are associated with placental abruption. Our instincts are to try to prevent preterm delivery to avoid the morbidity associated with it. This instinct is based on the premise that the problem is primarily one of prematurity. If, however, preterm labor in a particular patient is just a symptom of an underlying problem (infection, fetal stress, etc.), then vigorous attempts to prevent delivery, when successful, may only delay treatment of the underlying problem. Further, the medications commonly used to prevent premature delivery have significant side effects and risks. For these reasons, judgment is used to decide who should be treated for preterm labor and who shooed be allowed to deliver. In many civilian hospitals, no attempt is made to arrest labor after the 34th week. Threatened preterm labor consists of regular, frequent contractions (every 10 minutes) that do not lead to a change in the cervix. In many civilian hospitals, it is customary to withhold any labor-stopping medication until cervical change is noted. These civilian hospitals also have abundant resources to treat preterm labor and premature infants should labor unexpectedly progress rapidly. In an operational setting, such resources may not be available and earlier treatment may be indicated. In military settings, it is often helpful to postpone delivery long enough to get the patient to a definitive care setting, even if the patient is more than 34 weeks gestation. It is best to coordinate the use of these medications with the receiving facility. Any of the following treatments may effectively disrupt the labor process for 24-48 hours, and this is usually long enough to move the patient to an area of greater resource. Magnesium sulfate, 4 gm loading dose over at least 5 minutes, followed by 2 gm/hour in a steady IV drip. Watch for magnesium toxicity with diminished reflexes and respiratory depression, and treated with calcium. Ritodrine (Yutapar) 100 g/minute IV, increased every 15 minutes by 50 g to a maximum of 350 g/min. Titrate dosage to a maternal pulse of not less than 100 BPM and not greater than 120 BPM. Watch for pulmonary edema in the mother. Terbutaline 0.25 mg SQ, every 1-4 hours x 24 hours, total dose not to exceed 5 mg in 24 hours. May also be given PO in 2.5 - 7.5 mg doses, every 1.5 - 4 hours. Target maternal pulse rate is > 100 and < 120 BPM Indomethacin (Indocin), 50 mg PO (or 100 mg PR), followed by 25 mg PO every 4-6 hours for up to 48 hours. Watch for gastric bleeding, heartburn, nausea and asthma. Nifedipine, 10 -20 mg PO every 4-6 hours (Watch for headache, flushing and nausea). While postponing delivery, many fetuses less than 34 weeks gestation will benefit from administering steroids to the mother. The effect of the steroids on the fetus is to accelerate fetal pulmonary maturity, lessening the risk of respiratory distress syndrome of the newborn. Appropriate doses include: Betamethasone 12 mg IM, and repeated in 24 hours. Dexamethasone 6 mg IM Q 12 hours x 4 doses. When transporting the mother to a definitive care setting, have her remain way over on her left or right side, with a pillow between her knees, and an IV securely in place. If IV access is lost during a bumpy truck or helo ride, it will be nearly impossible to restart it without stopping or landing. Premature ROM Most women will rupture their membranes during labor. If membranes rupture prior to the onset of labor, this is called premature rupture of the membranes, or PROM. The obstetrical significance of PROM is that labor needs to begin promptly or infection will develop with bacteria ascending through the birth canal. In some cases of PROM, the reason the membranes rupture prematurely is because there is an established infection which has weakened the membranes. If the pregnancy is at full term and there is no evidence of infection, no treatment is necessary initially, because most women will go into spontaneous labor within the next 6 hours. After 6 hours of rupture, or in the face of infection or other pressing clinical circumstance, labor can be induced. Unless infection is evident, antibiotics are not helpful. When PROM occurs remote from term, two basic approaches can be taken...induce labor or wait for the fetus to mature further. There are pros and cons to each approach and the decision will hinge on individual clinical circumstances. This decision is best made in consultation with a definitive care facility. Confirmation of PROM is optimally made via a sterile speculum examination, looking for pooled amniotic fluid in the vagina, Nitrazine positive fluid, ferning positive fluid, and to obtain a culture of the fluid. Abnormal Presentation A fetus in transverse lie cannot deliver vaginally and requires a cesarean section to avoid uterine rupture during labor. Some of these women will also have a placenta previa (as the cause of the transverse lie). Others will need an urgent cesarean because of prolapsed cord. Without the fetal head or butt occupying the birth canal, it is relatively easy for an umbilical cord to prolapse through a widely dilated cervix with ruptured membranes. A compound presentation may be resolvable if the fetus can be encouraged to withdraw the hand, for example. If the fetus and arm are relatively small in comparison to the maternal pelvis, vaginal delivery may still be possible, but with some risk of injury to the arm. The bones of the fetal scalp are soft and meet at "suture lines." Over the forehead, where the bones meet, is a gap, called the "anterior fontanel," or "soft spot." This will close as the baby grows during the 1st year of life, but at birth, it is open. The anterior fontanel is an obstetrical landmark because of its' distinctive diamond shape. Feeling this fontanel on pelvic exam tells you that the forehead is just beneath your fingers. The occiput of the baby has a similar obstetric landmark, the "posterior fontanel." This is a crossing of suture lines in a Y shape that is very different from the anterior fontanel. In cases of fetal scalp swelling or significant molding, these landmarks may become obscured, but in most cases, they can identify the fetal head position as it is engaged in the birth canal. The fetal position is usually described using three letters. LOA means the fetal occiput is directed towards the mother's left, anterior (front) side. ROT means right occiput anterior. These anterior presentations are normal and usually are the easiest way for the fetus to traverse the birth canal. LOT (Left, Occiput, Transverse) position and its' mirror image, ROT, are common in early labor. As labor progresses and the fetal head descends, the occiput usually rotates anteriorly, converting this LOT to an LOA or OA as the head delivers. If the head fails to rotate despite steady descent, this is called a "deep transverse arrest," and is common among: Babies who are too big to come through, and Mothers with flat pelvises that favor a transverse delivery Women with this condition who fail to deliver spontaneously are treated with cesarean section, forceps, or vacuum extraction, depending on the clinical circumstances, available resources, and experience of the operator. LOP (Left Occiput Posterior) and ROP (Right Occiput Posterior) are positions favored by certain internal pelvic shapes. This position has some obstetrical significance. Normally, if the head is at 0 Station, the biparietal diameter is at the pelvic inlet and the head is fully engaged. In posterior positions, at 0 Station, the biparietal diameter is still a couple centimeters above the pelvic inlet, meaning that the head is not fully engaged. Babies can deliver in the posterior position, but the pelvis needs to be large enough and it usually takes longer. Forceps are often used to deliver babies in this position, but there is controversy whether the fetus should be delivered in the posterior position, or rotated with the forceps to the anterior position. Much depends on the clinical circumstances and the experience of the operator. Prolonged Latent Phase Labor Latent phase labor lasting longer than 20 hours in a woman having her first baby or more than 14 hours in other women is considered a "prolonged latent phase." Women with a prolonged latent phase risk exhaustion and an increased risk of uterine infection (chorioamnionitis). No single treatment of prolonged latent phase will necessarily be successful in nudging the patient into active phase labor, but each of the following have been successful in many patients: Rest Ambulation Hydration Analgesia (narcotics such as Demerol 50-100 mg IM, Morphine 7.5-15 mg IM, Dilaudid 1-2 mg IM, etc.) Oxytocin stimulation Arrest of Active Labor Normal labor progresses at a rate of no less than 1.2 cm/hour (for first babies) to 1.5 cm/hour (for subsequent babies). If active labor progresses more slowly than this, an "arrest of labor" has occurred. The arrest of labor may be simple slowing of the labor below the expected rate, or may represent a complete arrest, in which there is no further progress for at least 2 hours. There are essentially only two causes for an arrest of labor: Inadequate contractions, or Mechanical impediment to the progress of labor. Contractions may be inadequate because they are too infrequent (more than 4 minute intervals), or do not last long enough (less than 30 seconds). Often in this situation, they are neither frequent enough nor long enough. Mechanical impediments to labor may include: Absolute feto-pelvic disproportion, in which the maternal pelvis is not large enough to allow the baby to pass through the birth canal. Relative feto-pelvic disproportion, in which there is a snug fit, but given time and adequate contractions, the baby can safely negotiate the birth canal Fetal malposition, in which the fetal head is presenting in a less favorable position (for example, occiput posterior, or with fetal hand preceding the head, or a transverse lie) Asynclitism, in which the fetal head is angled slightly to one side, making it more difficult for a clear passage through the birth canal. Inadequate contractions are treated with uterine stimulation. This is generally accomplished with intravenous oxytocin, delivered in steady, small amounts with a controlled infusion pump. The dose is started relatively low, and then advanced gradually until the desired effect is achieved. Later in labor, the dosage is often adjusted downward or stopped altogether if the contractions are too close together (consistently more than 5 contractions every 10 minutes). In an operational setting where a controlled infusion pump is not available, two other options can be employed: 10 units of oxytocin are put in a 1-liter IV. With one hand on the maternal abdomen to palpate uterine contractions, the other hand adjusts to flow rate of the IV. Initially, just a few drops are infused and the effect assessed. If the patient shows no unusual degree of sensitivity, the IV flow rate is gradually increased until the desired effect is obtained. This will often take 45 minutes to an hour of careful adjustment. This technique is not as safe as a controlled infusion pump, but it is still safe enough to be used if the need for oxytocin is great and the resources are limited. A common occurrence with this technique is overstimulation of the uterus resulting in a prolonged, tetanic contraction. Usually this will resolve with time, but occasionally it is so severe as to cause a uterine rupture. For that reason, careful monitoring of the fetus during this application of oxytocin is very important and immediate availability of surgical resources is very desirable. Nipple stimulation (rolling the nipple back and forth with thumb and forefinger) will cause of release of the mother's own oxytocin from her pituitary gland. This will have the effect of stimulating contractions. Stimulating both nipples will have about double the effect as stimulating one nipple. After about 15-20 minutes of nipple stimulation you will have released about as much natural oxytocin as is available. Nipple stimulation can be repeated at a later time, after the natural oxytocin supply has been replenished. While this technique can be effective, the biggest problem is overstimulation of the uterus because of too much oxytocin. Rather than achieving more frequent, longer contractions, you will end up with a single, 3-5 minute contraction that is threatening to the fetus and the integrity of the uterus. With that warning in mind, if the need is great and resources are limited, nipple stimulation can be effective in stimulating labor. Start with stimulation of just one nipple. Have the mother perform this on herself. It usually takes 3-5 minutes of this before you will notice any effect on the uterus. If gentle nipple stimulation is not effective, increase the strength of the nipple massage. If there is still no result, you can try stimulating both nipples. Just make sure to give the uterus enough time to respond. The possibility of a mechanical impediment should be considered whenever arrest disorders occur. If the fetus is in a transverse lie, it will not be able to deliver vaginally and continuing labor will ultimately lead to uterine rupture. If the fetus is in an occiput posterior position, vaginal delivery may still be successful, but it will take longer. If the fetus is a little large for the birth canal, vaginal delivery may still be successful, but only with time and fetal molding to the shape of the pelvis. If there is a compound presentation (head and hand, for example), the baby may still come through, but it may take much longer. (Try pinching the hand to see if the fetus will react by pulling it up and out of the way.) Usually, there is no way to know in advance which labors will experience an absolute obstruction and those that will not. For this reason, a trial of labor is almost always indicated. Those patients with an absolute obstruction will demonstrate a complete arrest pattern and will need cesarean section. Shoulder Dystocia Shoulder dystocia means difficulty with delivery of the fetal shoulders. Although this is more common among women with gestational diabetes and those with very large fetuses, it can occur with babies of any size. Unfortunately, it cannot be predicted or prevented. After delivery of the head, the fetus seems to try to withdraw back into the birth canal (the "Turtle Sign"). Digital exam reveals that the anterior shoulder is stuck behind the pubic symphysis. In more severe cases, the posterior shoulder may be stuck at the level of the sacral promontory.  Excessive downward traction, applied to try to get the baby out, can lead to injury to the nerves in the neck and shoulder (brachial plexus palsy) and should be avoided. While most of these nerve injuries heal spontaneously and completely, some do not. A generous episiotomy can be helpful. If a spontaneous laceration has occurred, or if the perineum is very stretchy and offers no obstruction, it is not necessary to also perform an episiotomy. Gentle downward traction can be attempted initially to try to free the shoulder. If this has no effect, do not exert increasing pressure. Instead, try some alternative maneuvers to free the shoulder. The MacRobert's Maneuver involves flexing the maternal thighs tightly against her abdomen. This can be done by the woman herself or by assistants. By performing this maneuver, the axis of the birth canal is straightened, allowing a little more room for the shoulders to slip through. While in the MacRobert's position, gentle downward traction can again be attempted.  Suprapubic pressure can be applied to drive the fetal shoulder downward, clearing the pubic bone. It is usually easiest to have an assistant apply this downward pressure while the birth attendant applies coordinated, gentle downward traction. Sometimes, the suprapubic pressure is more effective if applied in a somewhat lateral direction, rather than straight down. This tends to nudge the shoulder into a more oblique orientation, which in general provides more room for the shoulder. Gentle downward traction on the fetal head in combination with this suprapubic pressure may relieve the obstruction. Often, the posterior arm has entered the hollow of the sacrum. By reaching in posteriorly and sweeping the arm up and out of the birth canal, enough additional space will be freed to allow the anterior shoulder to clear the pubic bone. Identify the posterior shoulder and follow the fetal humerus down to the elbow. Then you can identify the fetal forearm. Grasping the fetal wrist, draw the arm gently across the chest and then out. If you try to remove an electric light bulb by simply pulling it out, it won't work. If, however, you unscrew the light bulb, it comes out relatively easily. The concept of unscrewing the light bulb can be applied to shoulder dystocia problems. As the shoulder rotates, it comes up outside of the subpubic arch. At the same time, the stuck anterior shoulder is brought posteriorly into the hollow of the sacrum. As the rotation continues a full 360 degrees, both shoulders are rotated (unscrewed) out of the birth canal. Applying fundal pressure in coordination with other maneuvers may, at times, be helpful. Applied alone, it may aggravate the problem by further impacting the shoulder against the symphysis. Two variations on the unscrewing maneuver include: Shoving the shoulder towards the fetal chest ("shoving scapulas saves shoulders"), which compresses the shoulder-to-shoulder diameter, and Shoving the anterior shoulder rather than the posterior shoulder. The anterior shoulder may be easier to reach and simply moving it to an oblique position rather than the straight up and down position may be sufficient Breech Delivery Breech babies can present in a variety of ways, including buttocks first, one leg or both legs first. Frank breech means the buttocks are presenting and the legs are up along the fetal chest. This is the safest position for breech delivery. If either foot is presenting ("footling breech"), there are increased risks of umbilical cord prolapse and delivery of the feet through an incompletely dilated cervix, leading to arm or head entrapment. Because of the risks of breech delivery, in many civilian hospitals most or all breech babies are born by cesarean section. In operational settings, cesarean section may not be available or may be more dangerous than performing a vaginal breech delivery. The simplest breech delivery is called a spontaneous breech. The mother pushes the baby out with the normal bearing down efforts and the baby is simply supported until it is completely free of the birth canal. These babies pretty much deliver themselves. This works best with smaller babies, mothers who have delivered in the past, and frank breech presentation. If the breech baby gets stuck half-way out, or if there is a need to speed the delivery, an "assisted breech" delivery is performed. For this type of delivery, it is very helpful to have a second person to aid you. A generous episiotomy will give you more room to work, but may be unnecessary if the vulva is very stretchy and compliant. Grasp the baby so that your thumbs are over the baby's hips. Rotate the torso so the baby is face down in the birth canal. A towel can be wrapped around the lower body to give the you a more stable grip. Have your assistant apply suprapubic pressure to keep the fetal head flexed. Exert gentle outward traction on the baby while rotating the baby first clockwise and then counterclockwise a few degrees to free up the arms. If the arms are trapped in the birth canal, you may need to reach up along the side of the baby and sweep them, one at a time, across the chest and out of the vagina. It is important to keep you hands low on the baby's hips. If you grasp the baby above the hips, it is relatively easy to cause soft tissue injury to the abdominal organs, including the kidneys. During the delivery, always keep the baby at or below the horizontal plane or axis of the birth canal. If you bring the baby's body above the horizontal axis, you risk injuring the baby's spine. Only when the baby's nose and mouth are visible at the introitus is it wise to bring the body up. The application of suprapubic pressure by the assistant is important for keeping the head flexed against the chest, expediting delivery, and reducing the risk spinal injury. At this stage, the baby is still unable to breathe and the umbilical cord is likely occluded. Without rushing, move steadily toward a prompt delivery. Placing your finger in the baby's mouth may help you control the delivery of the head. Try not to let the head "pop" out of the birth canal. A slower, controlled delivery is less traumatic. Twin Delivery About 40% of twins present as cephalic/cephalic. The remainder pose some abnormal presentation of one or both twins. Because of the abnormal presentations and the complexities of delivering twins, many are delivered by cesarean section in civilian settings. Some physicians favor cesarean delivery for all twins. In many operational settings, this approach may not be available or wise, and vaginal delivery may be performed. Following delivery of the first twin, there is a period of time during which contractions slow or stop. Both placentas remain inside the uterus and attached. It is usually safest to make no attempt to speed up this process, but to await the resumption of contractions. This could take a few minutes or many minutes. While waiting, monitor the second twin's heart beat and if normal, continue to observe the patient. If contractions do not promptly resume, it is acceptable to stimulate the uterus with oxytocin. With your hand in the vagina, feel the fetal presenting part. If it is not engaged, try to guide it down to the pelvic inlet. Avoid rupturing membranes until the fetal presenting part is engaged in the birth canal. As the presenting part descends, ask the mother to bear down and usually the second twin will deliver as easily as the first twin. First twins are usually bigger than their sibling. Prolapsed Umbilical Cord If a portion of the umbilical cord comes out of the cervix or vulva ahead of the fetus, this is called a prolapsed umbilical cord. This can be a big problem for the fetus if the cord is compressed, blocking the flow of blood to the baby. Immediate delivery is the best solution to this problem. If immediate delivery is not available, put the mother in the knee-chest position and use your hand in her vagina to elevate the fetal head back up into the uterus. This action may relieve enough pressure on the umbilical cord that oxygen can still get through to the baby. Transport the mother in the knee-chest position and you with your hand elevating the fetal presenting part to the nearest facility in which immediate delivery is possible. Cord Around the Neck This is a frequent occurrence during delivery. Nearly half of babies have the umbilical cord wrapped around something (neck, shoulder, arm, etc.), and this generally poses no particular problem for them. In a few cases, the cord will be wrapped so tightly around the baby's neck (after delivery of the head but before the shoulders are delivered) that you cannot get the rest of the baby out without risk of tearing the umbilical cord. If you can easily slip the cord over the baby's head, go ahead and do that. If the cord is relatively loose, and allows the baby to be born with the cord around its' neck, go ahead and do that. If the cord is tight and disallows any manipulation, double clamp the cord and cut between the clamps. This will free the cord. With this approach, prompt delivery of the rest of the baby is important. Retained Placenta After delivery of the baby, the placenta will detach from the inside of the uterus and will be expelled, often with additional pushing efforts by the mother. Normally this occurs within a few minutes of delivery of the baby, but may take as long as an hour. Often after about 30 minutes of waiting, a manual removal of the placenta is undertaken. Anesthesia (regional or general) is typically used for this as manual removal causes a great deal of abdominal cramping. In operational settings, if necessary, it may be performed without anesthesia or with some IV narcotic analgesia. One hand is inserted through the introitus and into the uterine cavity. Grasp the edge of the placenta and use the side of your hand to sweep the placenta off the uterus. Then pull the placenta through the cervix. Most placentas can be easily and uneventfully removed in this way. A few prove to be problems. When you manually remove the placenta, be prepared to deal with an abnormally adherent placenta (placenta accreta or placenta percreta). These abnormal attachments may be partial or complete. If partial and focal, the attachments can be manually broken and the placenta removed. It may be necessary to curette the placental bed to reduce bleeding. Recovery is usually satisfactory, although more than the usual amount of post partum bleeding will be noted. If extensive or complete, you probably won't be able to remove the placenta in other than handfuls of fragments. Bleeding from this problem will be considerable, and the patient will likely end up with multiple blood transfusions while you prepare her for a life-saving, post partum uterine artery ligation or hysterectomy. If surgery is not immediately available, consider tight uterine and/or vaginal packing to slow the bleeding until surgery is available. Post Partum Hemorrhage Average blood loss following a delivery is about 500 cc. Bleeding that is significantly in excess of that is considered post partum hemorrhage. The uterus not contracting firmly after delivery causes most cases of post partum hemorrhage. In some cases, there is a retained blood clot inside the uterus which disallows a firm, tight contraction. Manually expressing the blood clot by squeezing the fundus will usually control bleeding from this source. Uterine massage is an immediate treatment, often very effective, in stopping the bleeding. Oxytocin can be added: Oxytocin 20 units in 1 liter of IV fluids, run briskly (wide open) for a few minutes will flood the mother with a strong uterotonic agent. Oxytocin 10 units IM will take longer to be effective, but will have a more sustained action and is immediately available without an IV. Methylergonovine maleate 0.2 mg IV or IM will firmly contract the uterus, but should be used cautiously if at all in women with pre-existing hypertension. Prostaglandin F-2-alpha can be effective but is rarely available in operational settings. Bimanual compression of the uterus is an effective way of slowing or stopping the bleeding associated with post partum hemorrhage. The uterus is elevated out of the pelvis by the vaginal hand, and compressed against the back of the pubic bone by the abdominal hand. Blood transfusion may be life saving in some of these patients. In a non-pregnant patient, the predictable signs of tachycardia, hypotension and tachypnea before confusion usually accompany progressive hypovolemia and loss of consciousness occur. Women with immediate post partum hemorrhage do not necessarily follow that path and may look surprisingly well until they collapse. Because of this, your decision to give or not give blood to these women should depend heavily on your estimated blood loss, clinical circumstances and likelihood of continuing blood loss, and less on her vital signs. Women who quickly lose half their blood volume (2500 out of 5000 ml) usually benefit from transfusion. In civilian settings, banked blood is usually given. In many operational settings, banked blood is not available and fresh, whole blood will be used. Chorioamnionitis Chorioamnionitis is an infection of the placenta and fetal membranes. In its' earliest stage, there may be no symptoms or clinical signs. As it becomes more advanced, clinical evidence of infection may appear, including: Elevated maternal temperature above 100.4. Elevated maternal white blood count Fetal tachycardia Foul-smelling amniotic fluid Uterine tenderness Chorioamnionitis may be a problem for both the mother and the fetus. Maternal infections can prove to be very serious. The fetus may suffer not just from infection, but also because of the elevated core temperature of the mother. Increased core temperatures lead to an increased metabolic rate of the fetal enzyme systems, which in turn need more oxygen than normal. At times, this increased oxygen demand cannot be met and the fetus may become progressively acidotic. Chorioamnionitis during labor is usually treated very aggressively, with broad-spectrum, intravenous antibiotics such as: Ampicillin 2 gm IV every 6 hours, plus gentamicin 1.5 mg/kg (loading dose) and 1.0 mg/kg every 8 hours Ampicillin/sulbactam 3 gm IV every 4-6 hours Mezlocillin 4 g IV every 4-6 hours Piperacillin 3-4 g IV every 4 hours Ticarcillin/clavulanic acid 3.1 gm IV every 6 hours Maternal temperature is treated with oral or rectal acetaminophen, 1 gm every 4 hours. Plans are made for prompt delivery. Group B Streptococcus GBS is a source of significant morbidity and sometimes mortality. Many women are asymptomatic carriers. A variety of schemes to reduce perinatal GBS infections have been proposed and used in different civilian settings. In operational settings, once good way of dealing with this issue is to treat on the basis of risk factors. Using this approach, women with any of the following risk factors are treated for possible GBS: Previous infant with invasive GBS disease Documented GBS bacteruria during this pregnancy Delivery at <37 weeks gestation Ruptured membranes 18 hours or longer Fever during labor of 100.4 or greater Treatment consists of: Penicillin G, 5 million units IV, followed by 2.5 million units IV every 4 hours until delivery, or Ampicillin 2 gm IV, followed by 1 gm IV every 4 hours until delivery, or Clindamycin 900 mg IV every 8 hours, or Erythromycin 500 mg IV every 6 hours until delivery, or Other broad-spectrum antibiotics if clinically indicated Post Partum Fever Maternal febrile morbidity is classically defined as temperatures exceeding 100.4 on at least two occasions, at least 6 hours apart. For patients with an obvious infection with high fever, localizing signs and septic in appearance, treatment is initiated prior to fulfillment of the 6-hour definition. Cultures from the urine and vagina (and sometimes blood) can be useful in civilian settings. In operational settings, their value may be limited. Similarly, a chest x-ray, which might be ordered and promptly obtained in a civilian setting may not be available or of any practical value in a military setting. Examine the patient, looking for localizing signs that will guide you in your therapy. Check for: Uterine tenderness, suggesting a uterine or endometrial source Flank tenderness, suggesting pyelonephritis Breast tenderness and redness, suggesting mastitis Perineum tenderness and redness, suggesting wound infection Pulmonary rales, rhonchi or wheezes, suggesting a respiratory source Calf tenderness, suggesting deep vein thrombophlebitis If a specific source is identified, treatment specific for that source can be employed. However, in operational settings, there is considerable risk of multiple sources and vigorous antibiotic therapy is generally initiated. Good choices for such therapy include: Ampicillin 2 gm IV every 6 hours, plus gentamicin 1.5 mg/kg (loading dose) and 1.0 mg/kg every 8 hours, plus clindamycin 900 mg IV every 6 hours Ampicillin/sulbactam 3 gm IV every 4-6 hours Mezlocillin 4 g IV every 4-6 hours Piperacillin 3-4 g IV every 4 hours Ticarcillin/clavulanic acid 3.1 gm IV every 6 hours Cefotetan 1-2 g IV every 12 hours Care of the Newborn Dry the Baby Immediately after delivery, the baby should be dried. Ideally, this is with a warm, soft towel, but don't delay in drying the baby while searching for a warm, soft towel. Any dry, absorbing material will work well for this purpose. This would include: Shirts T-shirts Gloves Battle dressings Jackets Socks Replace the Wet Towels Babies can lose a tremendous amount of heat very quickly, particularly if they are wet. By removing the wet towels and replacing them with dry towels, you will reduce this heat loss. Babies, during the first few hours of life, have some difficulty maintaining their body heat and may develop hypothermia if not attended to carefully. This is particularly true of premature infants. Position the Baby Babies should be kept on their backs or tilted to the side, but not on their stomachs. The orientation of the head relative to the body is important for breathing. In adults, this orientation is not usually crucial; adults tolerate a relatively wide range of head positioning without compromising their airway. Not so with newborns who have a relatively narrow range of head positioning that will permit air to move unimpeded through the trachea. The optimal position for the baby is with the head neither markedly flexed against the chest, nor extended with the chin up in the air. Instead, the head should be in a "military" attitude, looking straight up. Position the baby on its' back with the head looking straight up. This will usually provide for good airflow. If there is any airway obstruction, make small adjustments to the head position to try to straighten the trachea and eliminate the obstruction. Suction the Airway When babies are born, they need to clear the mucous and amniotic fluid from their lungs. Several natural mechanisms help with this: As the fetal chest passes through the birth canal it is compressed, squeezing excess fluid out of the lungs prior to the baby taking its' first breath. This is noticed most often after the fetal head is delivered but prior to delivery of the shoulders. After several seconds in this "partly delivered" position, fluid can be seen streaming out of the baby's nose and mouth. After birth, babies cough, sputter and sneeze, mobilizing additional fluid that may be in their lungs. After birth, babies cry loudly and repeatedly, clearing fluid and opening air sacs in the process. Crying is a reassuring event and does not indicate distress. Newborn grunting actions may further mobilize fluid, in addition to opening the air sacs in the lungs. While babies will, for the most part, bring the amniotic fluid out of the lungs on their own, they may need some assistance in clearing their airway of the mobilized fluid. This will require suctioning. Bulb syringes are commonly used for this purpose, suctioning both the nose and mouth of the baby. If a bulb syringe is not available, any suction type device may be used, including a hypodermic syringe without the needle. If no suction device is available, keep the baby in a slight Trendelenburg position (head slightly lower than the feet) and turn the baby to its' side to allow the fluids to drain out by gravity. Evaluate the Baby Evaluate the baby for breathing, color and heart rate. If the baby is not breathing well or is depressed, additional drying with a towel may provide enough tactile stimulation to cause the baby to gasp and recover. Babies are not slapped on their buttocks for this purpose, although flicking the soles of the feet with a thumb and forefinger can provide enough noxious stimulation. Color Asses the pinkness of the fetal skin. Although some newborn infants are uniformly pink in color, many have some degree of "acrocyanosis." This means that the central portion (chest) is pink, but the extremities, particularly the hands and feet, are blue or purple. Acrocyanosis is normal for a newborn during the first few hours, disappearing over the next day. It is due to relatively sluggish circulation of blood through the peripheral structures, related to immaturity or inexperience of the newborn blood flow regulatory systems. Central cyanosis is not normal and indicates the need for treatment. It is due to the accumulation of desaturated (oxygen-depleted) hemoglobin. Opening the airway treats cyanosis due to airway obstruction. Ventilating the baby treats cyanosis due to inadequate ventilations. In mild cases, cyanosis may be resolved by providing 100% oxygen to the baby. Ventilate if Necessary If, after a brief period of tactile stimulation, the baby is not making significant respiratory efforts, you should begin artificial ventilation, using whatever materials you have available to you. In ideal circumstances, this equipment would include a newborn mask, bag, 100% oxygen, pressure gauge, flowmeter, and flow control valve. In other than ideal circumstances, mouth-to-mouth ventilation may be the only available resource. Position one hand behind the newborn head and neck. This hand will make the small adjustments necessary to keep the airway open. Cover the newborn's nose and mouth with your own mouth. Use puffs of air to expand the baby's lungs. If you blow too forcefully or use too large a volume of air, you risk overexpanding the lungs, causing a pneumothorax. Check the Heartbeat The normal newborn heart rate is over 100 BPM. Pediatric stethoscopes can be used to listen to the heartbeat, but palpating the newborn pulse is easy to do and requires no special equipment. Even if the umbilical cord has been clamped and cut, the umbilical arteries can still be palpated. You will feel a strong tapping sensation if you feel the cord next to the baby with your thumb and forefinger. Alternatively, you can feel the brachial artery pulse, which courses down the medial aspect of the upper arm. If the pulse is less than 100 BPM, you should begin ventilating the baby artificially, using whatever equipment and skills that are available. Keep the Baby Warm Newborn hypothermia can occur quickly and depress breathing. It is very important to keep the newborn warm. This can be accomplished by covering the baby with clothing as soon as it is dried. Pay particular attention to keeping the head covered (but the airway open) as heat loss from the newborn head can be substantial. Typically, the baby is wrapped in warm, soft blankets and a head covering put in place. In sub-optimal circumstances, nearly any cloth material can be used keep the baby warm. Non-cloth material can also be effective in keeping the baby warm. Aluminum foil or Mylar reflective blankets provide satisfactory heat retention, particularly if used in air-trapping layers. If the mother is available, dry the baby, place the baby on the mother's chest, and cover both of them with blankets or clothing. The mother's body heat will help keep the baby warm. Check the baby's temperature several times during the first few hours of life. The normal range of newborn axillary temperature is about 36.5-37.4C (97.7-99.3F). Assign Apgar Score The Apgar score is a commonly-used method to assess the newborn status and need for continuing treatment. Points are assigned according to each of five categories. The total score is the sum of the points from each category, for a maximum of 10 points. The Apgar score is usually assigned at 1-minute after birth and again at 5-minutes after birth. Scores of 7 or more are considered normal. Those with normal scores may need some assistance and those with very low scores (0, 1 or 2) may need considerable assistance. Most newborn infants with low Apgar scores will be fine, once they are supported and resuscitated. Category0 Points1 Point2 PointsHeart RateAbsent<100>100Respiratory EffortAbsentSlow, IrregularGood, cryingMuscle ToneFlaccidSome flexion of ExtremitiesActive motionReflex IrritabilityNo ResponseGrimaceVigorous cryColorBlue, paleBody pink, Extremities blueCompletely pink Breast-feeding Babies can be breast-fed as soon as the airway is cleared and they are breathing normally. Some babies nurse vigorously while others are not particularly interested in feeding until several hours after birth. It is unwise to try to breast-fed babies with respiratory difficulties until the breathing problems are resolved. Breast-feeding babies generally make their needs known by crying when they are hungry. They also cry when they are uncomfortable from a wet or soiled diaper. Sometimes, they cry because they need to be picked up and held. Field-Expedient Bottle If the mother is not available for breast-feeding, alternative ways to feed the baby are nearly always possible. Essential to this process is an artificial nipple or nipple-like structure. In an operational setting, formula can be placed in a latex glove (after rinsing out any cornstarch or other material) and a small perforation made in the end of a finger. The baby can then suck on the fingertip. While this works acceptably, a big problem is that the nipple (latex glove) collapses as soon as the baby starts to suck. Some formula will come through, but it is not the same as a normal nipple and the baby will likely become very frustrated. Putting formula in a canteen and slipping the latex glove over the spout works better (it's harder to collapse the nipple). Try to warm the formula to body temperature before feeding. If formula is not available, sugar water can provide fluid and a few calories on a temporary basis. Cows milk should be avoided unless there is no other alternative and access to baby formula is not expected any time soon. Vernix Babies are usually born with a white, cheesy coating on their skin called "vernix." This is a combination of skin secretions and skin cells. While excess vernix can be cleaned from the baby, it is not necessary to remove all of it as it has a protective effect on the baby's skin. Meconium Meconium is the dark green fecal material that babies pass after delivery and sometimes before delivery. If the amniotic fluid is green colored, this is due to the presence of meconium and is found in as many as one in five deliveries. Babies subjected to intrauterine stress often pass meconium before delivery, but so do many non-stressed fetuses. The presence of meconium is significant because is indicates the need to thoroughly clear the airway of meconium. In a hospital setting, this is often accomplished with endotracheal visualization or intubation. In operational settings, endotracheal intubation of the newborn may not be an option and careful suctioning with any available device will be performed. Eye Prophylaxis Within an hour of birth, treat the newborn's eyes to prevent gonococcal infection. Alternative medications include: 1% silver nitrate solution 1% tetracycline opthalmic ointment 0.5% erythromycin opthalmic ointment (This also prevents chlamydial infections) Vitamin K During the first few hours following delivery, a single injection of 0.5 to 1.0 mg of natural vitamin K can help prevent hemorrhagic disease. Umbilical Cord Care Keep the cord stump clean and dry. Daily wiping of the cord with alcohol and leaving it open to the air facilitates drying and discourages bacterial growth. Topical application of antiseptics is usually not necessary unless the baby is living in a highly contaminated area. Medical Support of Women in Field Environments Pre-deployment Planning Planning for the medical support of women in operational environments is important for a successful operation. Four planning areas are particularly important: Supplementation of AMALs (standard equipment and supplies) and Sick Call Blocks to support female personnel Establish Command policy on deployment and medical evacuation of pregnant personnel Pre-deployment screening of deploying women Pre-deployment briefing of all personnel on women's health issues and host nation customs AMAL and Sick Call Block Knowing your available equipment and supplies is the first step. Perform a line-item review of AMAL contents by category to insure your familiarity with it. Frequently needed additional items include: Small size surgical gloves worn by female medical personnel and small males. Equipment required for pelvic exams. The need to provide for pelvic exams depends on your proximity to higher echelon operational and fixed MTF's (Medical Treatment Facilities). If a better equipped US Military facility nearby is able to provide this service, you may not need to establish this capability. Maintaining pelvic exam capability requires considerable logistical planning and funding. Do not assume that every higher echelon facility has this capability - check before you deploy. Speculums - small and medium. Disposable types are good because the ability to clean and repackage speculums in the field is limited. However, metal instruments may be the only type available and have the advantage of being reusable. Light source - You will need some type of light source that can be directed as needed. Goose neck or fiberoptic lights are nice but not always available. Automotive type caged "shop lights" provide excellent operational lighting, can be hung anywhere, and are inexpensive. Drapes - Some type of draping for exams should be provided, disposable or fabric. Disposable drapes are rarely available. Bed linens (sheets and blankets) are not included in AMALs. You'll need to obtain these from unit supply. Note: you'll need some means to wash non-disposable linens. Microscope - ideally needed to perform wet-preps of vaginal discharge, but this is optional as general clinical guidelines can be used for brief field operations. Consumable supplies - normal saline, KOH, microscope slides, coverslips, lens paper, large and small cotton tip applicators, K-Y Jelly, and stool guiaic kit. Equipment for early OB care. This capability should be taken into an operational setting only when large numbers (100+) of deployed women are to be supported in a highly isolated setting or when civilian humanitarian operations require. An OB "Wheel" is very helpful. Tape measure. It is helpful for measuring fundal heights and for assessing any structure that might be enlarging over time, such as masses, cysts, hematomas, etc. Fetal Doppler. There is no good substitute for a fetal Doppler. The DeLee stethoscopes are effective after 20 weeks of pregnancy, but require some practice to be proficient. A Doppler is much easier. Remember to bring ultrasonic conductive gel. If you don't have any, any water-soluble lubricant such as K-Y jelly, will serve reasonably well as a sonic conductor. Even water is better than nothing. Bedpan. This not only serves the obvious function but provides excellent buttocks elevation for pelvic exams and precipitous deliveries. For routine obstetrical care, it is useful to have some forms, including a prenatal risk assessment form and a standard pregnancy form. Bring a precipitous delivery package...just in case! Prenatal vitamins. Iron tablets. BCPs. Make sure to pack an adequate supply of birth control pills (Lo Ovral is a good, multipurpose BCP). Each deploying woman should bring enough BCPs to last for the entire deployment, but sometimes they get lost or damaged, and sometimes you'll need extra BCPs to treat specific problems such as bleeding, pain, or as emergency contraception. Have some antibiotics appropriate for urinary tract infections. Septra, Bactrim and Macrodantin all work well for this. Women have many more UTI's than men and are particularly vulnerable to them in a field environment. In addition to antibiotic, having a urinary tract analgesic will enable you to keep your patients with UTI's functional while treating their bladder infection. These turn the urine a vivid red-orange color and this is of clinical significance because: 1. Women who are not aware of the urinary color change caused by these dyes can be very alarmed. 2. Soldiers who are using the color of their urine to monitor their hydration status will be unable to use this method while taking the dye. Antifungal medication. Creams such as Monistat or GyneLotrimin work well, but are messy in the field environment. Diflucan tablets (150 mg PO once) are highly effective, take up very little space, but are relatively expensive. Women who have frequent yeast infections should bring their personal preference for antifungal medication with them. Metronidazole. It is very effective against many enteric infections, trichomonads and bacterial vaginosis (anaerobic vaginal bacterial infections). All of these are common in field situations, making Flagyl very useful. Lidocaine cream or gel, for genital herpes outbreaks can relieve discomfort and keep personnel functional. Sexual assault kit. These can usually be obtained free from the Naval Criminal Investigative Service. For major or remote deployments take a sexual assault kit even if you do not have pelvic exam capability. It is best not to rely on higher echelons for this. Pregnancy test kits. Urine HCG test capability is not included in the laboratory AMALs used by echelons 1 and 2. They are strongly recommended for units deploying with women. Urine dipsticks. These are useful for providing information regarding UTI's, renal stones, liver disease, and hydration status. Command Pregnancy Policy Establish Command Policy on deployment of pregnant women. Though some of the military services may allow for limited deployment of some pregnant women during early pregnancy, that does not mean it is a good idea for your particular deployment. The reasons for this are many: Ectopic pregnancy occurs relatively frequently (about one in one hundred pregnancies or more). Unless intrauterine pregnancy has been demonstrated by ultrasound prior to deployment, the risk of ectopic remains a possibility. Ruptured ectopics are life-threatening emergencies even in ideal circumstances. In isolated settings, they are particularly dangerous. One in five pregnancies ends in miscarriage in the 1st trimester. 50% of women with bleeding in the 1st trimester go on to have a miscarriage. Echelon 1 and 2 MTF's are not designed to manage miscarriages and likely will not be able to deliver optimal care for them. Miscarriage management requires the ability to not only perform dilatation and curettage if required, but also to type blood and administer Rhogam if needed. General Medical Officers do not typically possess the training and skills to confidently manage early pregnancy problems. Where GMO's have significant training in OB, their decision-making is based on the availability of hospital-type diagnostic information: qualitative and quantitative HCG, progesterone levels, and ultrasounds, none of which are usually available to them in operational settings. Many significant clinical care events occur in the first 20 weeks of pregnancy. Early OB patients must be monitored for timely appearance of fetal heart tones with doptone and fetoscope and quickening. They must be offered alpha fetoprotein and other tests within certain gestational windows for optimal management. Operationally deployed women may not have the opportunity to get this time-sensitive care by qualified providers. Emergency MEDEVAC of unstable obstetric patients is dangerous. Operational MEDEVACs often challenge aircraft range, occur in poor visibility and require take-off and landing on small, poorly appointed fields and pads. Exposure to extremes of temperature in uninsulated tactical aircraft may exacerbate shock in bleeding patients. Noise, vibration, poor patient access, and poor lighting further complicate patient management in flight. Routine transfer of stable pregnant patients is much safer for all and preserves warfighting assets. The operational setting is often environmentally challenging for pregnant women. Extreme heat may exacerbate risk of fainting (and falling). Complicating the management of morning sickness and potential dehydration are the realities of field chow, extreme heat, and porta-potties. Command Policy usually follows one of three directions: Immediate transfer out of the operational setting. In general, keeping the pregnant woman in the operational setting as long as service guidelines are met. Prompt transfer out of the operational setting when it is tactically convenient. Each of these approaches has its' merits and it may prove useful for you to discuss with your Command their preference in managing pregnancy. Cultural considerations: Some religions or cultures attach extreme negative stigma to pregnancy out of wedlock. In some countries, women and their children may be stoned to death for violation of this ethic. When unmarried women are referred to civilian hospitals in some countries for OB care, be very careful. Some US military providers in some countries routinely transfer their unmarried OB or potential OB patients to more moderate, neighboring countries with a diagnosis that, while technically correct, does not denote pregnancy. This diagnostic expedient allows for care to be provided discreetly. Unmarried pregnant personnel should be transferred out of all countries with such strong cultural beliefs ASAP to avoid problems. Details on the cultural aspects of care in specific countries can be obtained from a supporting Operations and Medical Intelligence Officer. Pre-deployment Screening Starting a reasonable time before deployment, it is important to review the medical records for a variety of gynecologic issues. Perform pre-deployment screening of deploying women for: Up to date Pap smear and pelvic exam with abnormals followed-up. Acute or chronic OB-GYN problems Contraception Pregnancy Pre-deployment Briefing Provide a pre-deployment briefing to all deploying women, considering issues related to women's health. Specific areas to brief include: Urination issues Menstruation issues Bathing Quarters Selection of clothing Liberty risks for deployed women Leadership Host Nation issues Pregnancy STDs and safe sex Urination Issues Urinating in a field environment is sometimes an unpleasant, difficult, time-consuming, and dangerous task for women. To obtain privacy may require the woman to separate from the unit, placing herself in some degree of danger. Undressing sufficiently to urinate without soiling her clothing and then redressing usually requires many minutes. Balancing while squatting to urinate is usually not a practiced skill, and usually requires her to lay down her weapon. Using a fallen log or rock for support is sometimes worse than squatting. Even when sitting-position field latrines are available, they often are no bargain as far as cleanliness, odor, or comfort are concerned. The point is: urinating in the field environment is a function most women seek to avoid or minimize to the greatest extent that is physiologically possible. For women in military aircraft (helos and C-130's), the situation is not appreciably better. The design of jump and flight suits makes it impossible for a woman to urinate without completely disrobing, an awkward, embarrassing, and time-consuming evolution in the tight quarters of these aircraft. The primary means by which women avoid this is to not drink any liquids. This can be very effective in limiting urination as it rather quickly leads to dehydration. There are three problems: Physical and mental health in the field depend on remaining well-hydrated. Physical performance suffers in the presence of dehydration. Urinary tract infections are much more common among poorly-hydrated women. Some women in field operations find it more convenient and private to remain in their tent to urinate. Some have used empty, standard coffee cans with plastic lids (obtained from mess supply). The tent provides privacy and security and the women can urinate into the coffee can, close the lid, and carry it to a latrine for disposal of the urine and rinsing so the can may be re-used at a later time. Other women have used 1-gallon Ziplock bags for the same purpose. They pre-pack their dry clothing and underwear in Ziplock bags for the deployment. As they use up their dry clothing, they have Ziplock bags left over. Inside their tent, they can urinate into an empty bag, zip it closed, and then carry it to the latrine for disposal. Two commercial products that have been successfully field-tested by military women are the "Lady J" and "Freshette." Both of these enable women to urinate while standing and without extensive disrobing. Each has beneficial features. After opening the BDU fly, the plastic funnel is slipped inside the pants and underwear and held tightly against the vulva. Released urine is caught by the funnel, which then drains out the spout. The few drops of urine remaining in the system are shaken loose. They may be rinsed and stored for future use. The Lady J, having a relatively short drain, may not clear the BDU clothing. This requires vigilance to avoid wetting the clothing. The Freshette has a longer spout, clears the BDU clothing, and can be aimed in nearly any direction. With both of these products, some practice is usually required to become proficient. It is important to stress to deploying men and women the need to stay well-hydrated and drink plenty of fluids. On a Command level, it is important to provide as much opportunity as the tactical situation allows for women to urinate privately, without harassment, in an area close enough to the unit to provide security. Menstruation Issues Consider the following information in the pre-deployment brief: Encourage BCP users to continue their use during deployment. BCP's minimize dysmenorrhea, produce lighter flows (which is much easier to cope with), and eradicates worry of unplanned pregnancy in case of planned or unplanned sex (including rape). Encourage women with dysmenorrhea, dysfunctional uterine bleeding, problems with Depo-Provera, chronic pelvic pain, and clear need for contraception (history of unplanned pregnancy, recent abortion or delivery, STD's, unprotected intercourse) to start BCP's prior to deployment and stay on them throughout. Discourage the use of DEPO-PROVERA on deployment unless the patient has been a long term user. DEPO-PROVERA causes a significant number of women to have dysfunctional bleeding which can be troublesome during a deployment. For short deployments, time DEPO-PROVERA shots for delivery in garrison. If you want it in the field, you will need to supplement your AMALs. Consider the option of prolonged or continuous BCP use without withdrawal. Operationally deployed women can safely use BCPs continuously for many cycles (without the break to allow for a menstrual flow). Insure women deploy with adequate feminine hygiene products for prolonged periods without resupply. Remind tampon users to change their tampons at least every 8 hours to avoid the risk of infectious complications (PID, toxic shock, etc.) Use non-deodorant tampons, pads, and panty liners since the perfume can cause a dermatitis or vaginitis, predisposing the individual to further problems. Whether to bring tampons or sanitary pads on deployment is a personal preference decision, but the following should be considered: When operating in the field, wearing full BDUs (Battle Dress, Utility), EWCS (Extreme Weather Clothing), boots, flack jacket and tactical equipment ("782 gear" or "Deuce Gear"), it is time-consuming, difficult, and exposing to undress sufficiently to remove and replace a tampon. It is easier and faster to pull out a pad and replace it. Pads provide some protection of the genital area against the muck and grime of some field environments. They also absorb physiologic discharge and any urine leaks. Tampons provide no such protection and may "wick" dirty water up through the string, inoculating the vagina with whatever micro-organisms are present in the water. A box of tampons is very small, and takes up very little space in your gear. This is most useful for extended deployments, but may be important for short deployments as well. A box of pads takes up much more room. Minipads or panty liners are a good solution for many field issues. Some women deploy with enough pantyliners to use a fresh one each day. These women plan to wear the pantyliners continuously, to provide protection of their clothing against physiologic discharge and urine leaks. They also provide some protection against vaginal contamination with field water. They reduce the need for field laundering of clothing. Other women use pantyliners only as needed, finding them hot and somewhat uncomfortable, particularly when exercising. Wet wipes ("Wipes," "Baby Wipes," "Wet Naps," etc.) are very useful during a deployment. They are used not only for genital cleansing (toilet paper is sometimes unavailable or its' quality suboptimal) but also for hand and face washing or "wash cloth baths." Experienced women usually plan on using about 5-6 per day during a field deployment when access to washing and bathing facilities are limited or non-existent. These are taken either in a "travel pack" or, more often, placed in a zip-lock bag. Bathing In some operational settings, bathing facilities are plentiful and not an issue. In many other settings, showers may not be available for several days or even a week. Even then, the shower facilities may be suboptimal (field showers are not the same as showers in the barracks), lacking access, and privacy. Regular bathing is important, both for physical hygiene (preventing skin disease) and mental hygiene. Bring your own soap to the field and a small bottle of your personal preference for shampoo as you can't count on either one being provided in the field. When privacy is an issue in the shower, wear a nylon, one-piece bathing suit. You can still get very clean, the bathing suit (Speedo type) weighs nearly nothing, and takes up virtually no space in your pack. Use a low perfume soap (Dove(TM) or Zest(TM) are among the lowest.) or hypoallergenic bar. Prolonged contact with the perfume can predispose the individual to contact dermatitis and a chemical vaginitis. Quarters One issue that sometimes proves troublesome in the quartering or housing of men and women together in field environments. Two general approaches are taken: House the men and women from the same unit together in the same spaces. This will promote unit cohesion and provide uniform protection of all personnel. While this can create some privacy issues for both the men and women, experience has shown that these issues can be largely overcome by artful draping of poncho liners or shelter halves, combined with a generally understood sensitivity to the issue. House the men and women separately. This largely solves the privacy issue, but can create issues of jealousy (your tent is nicer than my tent) and sometimes safety, particularly if the women are housed at some distance from the men. It also interferes with the normal bonding that occurs among members of the same unit. Because of the relatively few women officers and senior enlisted, an additional problem of housing the women separately is limited direct supervision and guidance for the women. The Commanding Officer will decide which approach is best for this particular operational deployment. Clothing It is very useful for a deploying female servicewoman to bring a modest, dark colored, 1 piece, nylon, swimsuit which can be worn for "bathing" if privacy is a problem. Women should leave fragile undergarments at home and opt for sturdier selections. More delicate clothing may be lost from the laundry or clothes line if it survives field laundry. Sports bras and panties with a high cotton content launder well, support well, and minimize infections (intertrigo and vaginitis). Wear BDU pants loose. They are normally tailored with a high crotch, which may lead to vulvar irritation and vaginitis unless worn loose in field settings. What type of underwear to bring is a matter of personal preference, but these issues should be considered: Cotton underwear absorbs moisture and "breathes," allowing for circulation of air and promoting dryness in the vulvar area. This, in turn, reduces the chance of developing heat and moisture problems such as intertrigo and monilial infections. However, when engaged in strenuous physical activity (and sweating) over a long period of time, the cotton tends to bunch up into a wet, abrasive mass, leading to chafing and skin abrasions so severe as to be temporarily disabling. It may be unwise to use cotton underwear in field environments in which heavy exercise or marching long distances is anticipated. Nylon or polypropylene underwear or Lycra work-out shorts do not absorb moisture, but rather conduct it. During heavy exercise in field operations, moisture is conducted through the nylon and ultimately is absorbed and evaporated by the cotton in the fatigues (BDUs). The underwear itself remains relatively dry. This property make these types of underwear preferred by many women for exercise-intensive field operations. For sitting around a bivouac area, however, nylon underwear is hot, tends to trap moisture and keep it on the vulva, and may prove uncomfortable. Men often deploy on field operations without using any underwear at all. Most women will not find this approach practical, due to the normal physiologic vaginal discharge, the normal occasional leakage of urine and spotting in some women during strenuous physical exercise, and the difficulty in laundering in a field environment. It is much easier to wash out a pair of panties and let them dry overnight than to try to wash BDU (Battle Dress, Utility) pants, which usually won't dry overnight. Liberty Risks The buddy system works best for members of the same sex on liberty. Specific problems encountered by women: In most cases the number of operationally deployed women is extremely small. It may be difficult for a woman to find another woman she knows who is off duty at the same time with whom to go on liberty. Mixing male and female "buddies" creates problems for both sexes. Men interested in "adult male entertainment" avoid having female buddies. Men and women sharing liberty can establish (or be accused of establishing) inappropriate relationships which can impact marriage and professional performance. Some Commanding Officers establish a policy that men must accompany all women going on liberty from the unit. This is obviously a judgment call by the CO, weighing the problems of mixed-gender buddies (above) against the protective effect afforded the women by the presence of the men. Most COs will appreciate your input into that judgment. The potential for rape on deployment is significant. Deploying personnel should know that every allegation of rape will be formally investigated, even if the alleged victim later recants. If a woman was raped, a serious crime has occurred. If a woman alleges rape when none occurred, that is also a serious crime. No one in the chain of command should ever discount or ignore a report of rape. Inform deploying personnel that all potential victims will be offered injury and STD evaluation, emotional support, and emergency contraception whether or not they submit to forensic rape examination and/or press charges. Men deploying with women need to be careful to avoid situations leading to "date rape" allegations (alcohol abuse and sharing hotel rooms for any reason.) Leadership In comparison to men, women in the military have relatively fewer leaders in garrison, and this gap widens dramatically during deployment. In the Marine Corps, most units deploy a very small number of very junior women (usually LCPL's). It is uncommon to find a female SNCO and rarity to find a female officer. Many women find they have no direct supervision or guidance from anyone senior, male or female. It is important to recognize this leadership void and correct it. Male SNCO's need to go out of their way to take care of subordinate women marines. Female SNCO's and officers need to serve as supervisors, mentors, and spokeswomen for women who do not normally fall within their chain of command. Women should be encouraged to work together for their mutual safety and comfort. Supervisors should try to schedule female colleagues to work together to facilitate "buddying-up" on liberty as well. Such scheduling also prevents a woman from being alone on duty in isolated areas or traveling to and from places of duty alone at night. Host Nation Issues Brief all personnel on the position and conduct of women in the host nation society and encourage American women to conform to local standards of modest female behavior. Remember that some foreigners equate American women to Sharon Stone, Demi Moore and other actresses they see in the movies. American women are sometimes perceived as extremely sexually liberated by others. In some parts of the world, American servicewomen may attract unwanted attention just by being in the US military. Wear of typical American casual clothes like short-shorts, bikini's and halter tops may be seen as provocative (i.e., "asking for it") in conservative societies. Although it's nice to make new friends, American women should avoid situations where they might end up alone with host nation men, especially, in male-dominated societies. Pregnancy Place women on light duty and restrict deployment as soon as the HCG is positive. The formal command notification will be made following the new OB appointment. The patient also provides her own official command notification as directed by MCO 5000.13 (Marine Corps), OPNAVINST 6000.1A (Navy), AFI 44-102 (Air Force), or AR 40-501 (Army). Usually, this includes and acknowledgment of her responsibility to provide a written plan to the command that describes how her dependent will be cared for in her absence for duty purposes. If the pregnancy was unplanned, ask if the patient is considering abortion or adoption. Despite you moral convictions, it is appropriate to refer the patient to a counselor if she would like to discuss options. Elective abortion is not widely available in military hospitals. Many patients seek an abortion at their own expense. Obtain information from your local MTF. It is at the discretion of the Command to allow a woman who is deployed to leave her place of duty to seek an abortion. This is not a MEDEVAC event although space-A travel is possible. Abortion laws and availability in the civilian sector vary throughout the world. Even in garrison there may be occupational risks to a woman or fetus in an "industrial" work place. Work with Occupational Health to identify risks that can be avoided. Restricting her from all duties is rarely necessary, will short-change the command and may sabotage the patient's career. Be specific in limitations. For example: "No work with toxic chemicals, no work around fumes in spaces with poor ventilation, no work at heights above 3 feet without adequate protection from falls, etc." Noise Pregnant women must wear hearing protection when exposed to ambient noise levels above 84dBA, including infrequent impact noise. Brief exposure (5 minutes per hour or less) of hearing-protected pregnant women to ambient noise above 84dBA in order to transit high noise areas is probably safe. Prolonged exposure to this level of noise is not recommended. Pregnant women should avoid any exposure to ambient noise greater than 104dBA (corresponding to the need for double hearing protection), unless absolutely essential for quickly moving through a high noise area. The abdominal wall muffles (attenuates) the noise only somewhat and these very noisy areas may pose significant problems for the developing fetus. Heat Most pregnant women tolerate exposure to extreme heat poorly, for several reasons. Among them are the thermogenic effects of progesterone, changes in surface area to mass ratios, and the cardiovascular changes accompanying the pregnancy. Elevations of maternal core temperatures above 102 degrees are associated with increased risk of fetal malformations and pregnancy loss. It is wise to restrict prolonged exposure of pregnant women to very high temperatures, such as might be found in a ship's laundry, scullery or engine spaces. Organic Solvents These should be avoided while pregnant. Fumes can be a problem, but probably more important are spills that contact the skin. Lead, Cadmium, Mercury These can be highly toxic to the fetus. LFWBV Low Frequency Whole Body Vibrations (LFWBV) are strong, repeated body shaking such as would occur while operating a jack hammer. They are ill-advised at any time during pregnancy, but is probably particularly important after the 20th week of pregnancy. Prolonged Standing This is associated with more frequent pregnancy problems and should be avoided. STDs and Safe Sex It is unlikely than any amount of advocacy will change the morality and sexual attitudes of an adult. Character is well-established long before a person enters the military and it is probably impossible to effectively dictate morality. However, as medical providers, we may need to tell military personnel the medical risks of unprotected sex. Discussions could focus on: Risk of death from HIV, Hepatitis B, syphilis and cervical cancer Risk of cervical cancer from HPV Risk of infertility, sometimes occult, which may follow gonorrhea or chlamydia infections. Condoms are reasonably good protection against pregnancy, GC, chlamydia, HIV, Hep B and syphilis. They are not particularly good protection against herpes or HPV. Any sexual activity that avoids contact with a partner's body fluids is safer than one that doesn't. Sexual abstinence during deployment is the most effective method of preventing STDs and pregnancy. Aerospace Medicine Issues The aerospace environment places unique physiologic, mechanical, and logistic stresses on the aviator, male or female. In several important areas, women react differently to these stresses than men, among them: G tolerance Altitude sickness Anthropometrics/strength differences Pregnancy concerns For many reasons, much of the scientific evidence in these areas is only partially developed. Future studies with larger numbers of participants well clarify many of these issues. Gravitational Forces In high performance aircraft, aviators and crewmembers can be subjected to 9 Gs (Hypergravity) on a regular basis. This means functioning while forces make them feel up to nine times heavier than normal. Without countermeasures, people can have physiologic symptoms (loss of vision and G induced loss of consciousness or G-LOC being the most critical) at as low as three Gs. Effective countermeasures include Anti-G Straining Maneuvers (tensing arm and leg muscles with a valsalva) and life support equipment. Improving muscle mass and strength with weight lifting will improve the straining maneuver capability, and good cardiac conditioning enhances endurance. Each individual aviator has a base line G-tolerance affected by internal and external factors. In general, women have a higher baseline tolerance than men; however, there appears to be variability over menstrual cycles. In one very small study, there appeared to be a slight decrease in G-tolerance during ovulation and menses, and with certain oral contraceptives. Dehydration causes loss of G-tolerance in men and women. However, women aviators are more likely to begin a flight in a dehydrated state due to the lack of urinary relief devices in high performance airframes. It is important to encourage adequate hydration and good availability of lavatory facilities close to the flight line. Decompression Sickness Hypoxia and decompression sickness may have a higher attack rate in women. Hypoxia is caused by a lack of oxygen to the tissues. Hypoxic hypoxia is caused by a decrease in the available atmospheric oxygen at increased altitudes. If someone is anemic, a more common condition among women, symptoms will occur faster, i.e. at a lower altitude. Decompression sickness may occur whenever an individual is rapidly exposed to an environment with less than half the initial atmosphere. For instance, if one starts flying at sea level, half of the atmosphere is lost at 18,000 feet. The most common form of decompression sickness in aviation is the "bends", caused by bubbles of nitrogen, usually localizing around joints and manifested by pain. People with more "fat" are at greater risk for developing the bends. Women, because of their higher body fat composition, are more likely to have intravascular nitrogen bubbles, as a group, than men. NASA reports while women are more likely to have nitrogen bubbles, they are less likely to report symptoms than men. Studies from Brooks AFB revealed different findings, with women reporting more symptoms than men. Motivation to continue flying may have played a part in these differences. Anthropometrics Anthropometrics (size and shape of personnel) affects not only equipment fit, but also cockpit "fit". Smaller stature aircrewmembers of both genders may have difficulty reaching certain controls while maintaining visual reference points in some aircraft. Life support equipment was designed to fit the 5th to the 95th percentile male in 1950. About half of women will require at some modification of their equipment to obtain a good fit. Pregnancy in Aviation In the Air Force, pregnant aircrew members are grounded from all fixed wing airframes during the first and third trimesters, and from ejection seat aircraft for the entire pregnancy. The first trimester grounding is due to increased susceptibility to airsickness and teratogenicity. The third trimester is due to ability to egress and reach controls. Hypergravity during the first three cellular divisions can lead to fetal loss or birth defects in laboratory animals (birds and amphibians). It is difficult know how to extrapolate these potential risks in humans. Aircrewmember who fly in airframes capable of pulling in excess of three Gs and who experience infertility or pregnancy losses may benefit from temporary grounding until the pregnancy issues are resolved. Helicopters are noisy and provide sustained low frequency, whole boy vibration. Fetal noise exposure (threatening to fetal hearing) is only modestly dampened inside the mother's abdomen. LFWBV is associated with placental abruptions. Largely for these reasons, the US Army and USAF bar pregnant women from helicopters for the duration of their pregnancy. This chapter was written by: Colonel Carla Hawley-Bowland, MC, USA Captain Michael John Hughey, MC, USNR Commander Tamara C. Babb, MC, USN, FS Lieutenant Colonel Susan E. Northrup, USAF, MC, SFS The Prisoner of War Experience Lieutenant Colonel Rhonda Cornum, PhD MD Medical Corps, United States Army The Prisoner of War We all hope that no American serviceman, male or female, will be taken prisoner. Historically however, the risk of capture is small but real in all conflicts. Treatment of repatriated POWs has been discussed exhaustively, but has focused on men. Women have represented a very small percentage of the military, and until recently, an even smaller percentage of prisoners. Most of the information is probably equally applicable to female as to male repatriated POWs, but there has been nothing written specifically about the repatriation of women ex-POWs. As the only woman ex-POW still on active duty, I would like to share my views on the repatriation process. Sexual Abuse The primary concern of many health care providers (when faced with a returning female POW) seems to be the possibility of sexual abuse. I believe this emphasis on female sexual abuse is primarily cultural. I further believe this emphasis is derived from concerns about potential psychological after-effects of sexual abuse, and that it is based on the model of civilian women. It is vital to recognize that sexual abuse in the context of the POW experience is very different, for several reasons. Women in the military are not necessarily representative of the average American woman. A military career is still not considered a traditional path for women, and women who choose a military career may have a different willingness to take risk than women in the general population. They may not react like the average woman in the civilian setting. Most women in the military recognize that they are engaged in a high-risk occupation, and accept that there is a small but real risk of death and capture. Women in the military may have different priorities. For example, I was captured after being wounded by small arms fire and involved in a very significant aircraft shoot-down. My primary concerns were first, those that were life threatening (bleeding and internal injuries), followed by those that could result in permanent disability (multiple long bone fractures in my case). While I was subjected to an unpleasant episode of sexual abuse during my captivity, it did not represent a threat to life, limb or chance of being released, and therefore occupied a MUCH lower level of concern than it might have under other circumstances. It is my opinion that sexual abuse should be considered just one of many potential physical and psychological torture techniques, whether the subject is male or female. The Total Soldier Importantly, the health care provider encountering repatriated POWs should evaluate their total condition, and not focus on any single aspect of their condition unless it is obvious (broken bone, diarrhea, pregnant, etc). The repatriated soldier (it is important to avoid the term patient) will tell you his or her primary concerns, and the health care system should respond to those needs if at all possible. Pre-deployment Planning On a practical level, deployed women may find it valuable to use a method of birth control that does not require either daily input (the pill) or voluntary use (condoms or diaphragms). I recommend the IUD, Norplant, or Depo-Provera, particularly for women at higher risk, especially aircrew. It is important to introduce this concept before deployment, as it can be a social problem for monogamous women to suddenly begin a contraceptive program if their spouse does not understand the risk issue. The Typical Repatriated Soldier Because the circumstances of captivity are so different, it is difficult to describe a typical repatriated soldier. Some have been subjected to prolonged isolation and others not. Some have been physically abused and others not. Some have been held captive for a very long time, while others have been held only a short time. Clinically, they should be approached as individuals, with unique experiences and clinical needs. Stresses of Captivity While individual experiences vary, many common stresses of captivity may need to be addressed. Among these* are the physical stresses of: Crowding Diarrhea Epidemic diseases Exhaustion Forced labor Infectious organisms Injuries Medical experimentation Nutritional deprivation Sleeplessness Torture Weather extremes Wounds and the psychological stresses of: Boredom Close long-term affiliation Confinement Danger Family separation Fear/terror Guilt Humiliation Isolation Threats Unpredictability Recovery Most former POWs will fully recover from these physical and psychological stresses. Many will find a lasting emotional strength from their experience. * Textbook of Military Medicine, Office of the Surgeon General, United States Army, The Prisoner of War, P. 435, 1995 DEPARTMENT OF THE NAVY Office of the Chief of Naval Operations Washington, DC 20350-2000 OPNAVINST 6000.1A OP-136C1 21 February 1989 From: Chief of Naval Operations To: All Ships and Stations Subj.: MANAGEMENT OF PREGNANT SERVICEWOMEN Ref: (a) MILPERSMAN (b) NAVMEDCOMINST 6320.3B (c) NAVMEDCOMINST 1300.1B (d) ENLTRANSMAN (e) MANMED, Article 15-19 and 15- 56 (NOTAL) (f) NAVMEDCOMINST 6320.1A (g) OPNAVINST 5100.23B Encl: (1) Management of Pregnant Servicewomen 1.Purpose. To provide administrative guidance for the management of pregnant servicewomen, and to promote uniformity in the medical-administrative management of normal pregnancies. This instruction has been substantially revised and should be read in its entirety. 2.Cancellation. OPNAVINST 6000.1A 3.Background a. Pregnancy, by itself, should not restrict tasks normally assigned to servicewomen. b. The establishment and maintenance of worksites that allow Navy servicewomen to perform their assigned tasks, without adverse job-associated consequences, are a primary responsibility of command. This includes the elimination of detectable hazards, the prevention of occupational illness and injury, and the earliest treatment of job-associated morbidity. c. Pregnant servicewomen may have a heightened susceptibility to certain stresses and the effects of a normal pregnancy may necessitate job and/or watch modification on an individual basis. d. The safe completion of a pregnancy includes consideration of multiple factors: (1) General health status/condition. (2) Fertility difficulties/current pregnancy status. (3) Job/rate/rank/NEC/tasks assigned. (4) Lifestyle (smoking, alcohol, medicines). (5) Worksite. (6) Adequate obstetrical care meeting American College of Obstetricians Gynecologists Guidelines (ACOG). e. The fertility/pregnancy status will not adversely affect the career pattern of the Navy servicewomen. 4.Actions a. Fertility/pregnancy status as a factor affecting task accomplishment must be known to designated command officials while assuring the servicewoman's privacy. b. All personnel involved in the management of pregnant servicewomen are to be made aware of this instruction to obtain consistency in the management of pregnant servicewomen. The chapters of enclosure (1) are formatted to provide answers to the questions that may arise when a servicewoman becomes pregnant. The overriding concern is to safeguard the health of the pregnant servicewoman and that of her unborn child. Of concern also is the maintenance of job performance for as long as possible. 5. Forms. DD 689, Individual Sick Slip, S/N 0102-LF-007-0101, is available in the Navy supply system per NAVSUP P-2002. SF 513, Medical Record, NSN 7540-00-634-4127, is available from the General Services Administration. J.M. BOORDA Deputy Chief of Naval Operations (Manpower, Personnel and Training) Distribution: SNDL Parts 1 and 2 MARCORPS Code H Commander Naval Data Automation Command (Code 813) Washington Navy Yard Washington, DC 20374-1662 (340 copies) Stocked: CO, NAVPUBFORMCEN 5801 Tabor Avenue Philadelphia, PA 19120-5099 (500 copies) TABLE OF CONTENTS FOREWORD REFERENCES Section 1 - Servicewoman's Commanding Officer 101 - Responsibilities 102 - Medical Considerations of Work Assignment and Training 103 - Administration 104 - Convalescent Leave 105 - Breast-Feeding Section 2 - Servicewoman 201 - Responsibilities 202 - Waiver Request 203 - Obstetrical Care 204 - Infants Placed For Adoption 205 - Convalescent Leave Section 3 - Health Care Provider 301 - Responsibilities 302 - Light Duty 303 - Problem Pregnancies 304 - Hospitalization 305 - Postnatal Care 306 - Termination of Pregnancy 307 - Weight Standards 308 - Pregnant Brig Prisoners 309 - Breast Feeding Section 4 - Occupational Health Professional 401 - Responsibilities 402 - Approach 403 - Prepregnancy/Preventive 404 - Early Pregnancy/Risk Management 405 - Pregnancy/Job Modification Appendix A - Naval Environmental Health Center (NEHC) Potential Reproduction Questionnaire Appendix B - Occupational Reproductive Questionnaire Appendix C - Pregnancy Notification to Commanding Officer FOREWORD This directive provides a single-source document for the commanding officer, health care provider, occupational health professional, pregnant servicewoman, and others involved in the administrative and health care management of pregnant servicewomen. Users of this directive are encourage to submit recommended changes and comments to improve the publication. Comments should be keyed to the specific page, paragraph, and line of the text in which the change is recommended. Reasons should be provided for each comment to ensure understanding and complete evaluation. Comments should be directed to Chief of Naval Operations (OP-136), Washington, DC 20350-2000, by letter. This directive is meant to provide guidance for all active duty members. Reserve members must provide documentation of notification and approval by their primary obstetrical/gynecological physician prior to participation in active duty functions.
PRIVATEREFERENCES (a) MILPERSMAN (NOTAL) (b) NAVMEDCOMINST 6320.3B (c) NAVMEDCOMINST 1300.1B (d) ENLTRANSMAN(e) MANMED, Article 15-19 and 15-56 (NOTAL) (f) NAVMEDCOMINST 6320.1A (g) OPNAVINST 5100.23B 
CHAPTER ONE COMMANDING OFFICER 101. Responsibilities. a. General. After a pregnancy diagnosis is made and confirmed by a military medical treatment facility (or civilian health care provider in cases of inaccessibility to military facilities), a servicewoman's commanding officer must assure that the servicewoman retains a high degree of commitment to fulfill professional responsibilities. No preferential treatment shall be given because of pregnancy status. Specific limitations for the pregnant servicewoman are provided in this instruction. Additional limitations will require the judgment of the commanding officer in consultation with the health care provider and the occupational health professional. b. Counselling (1) Commanding officers shall ensure that the provisions of this instruction and MILPERSMAN Articles 3620220, 3810170 and 3810180 are brought to the attention of any servicewoman desiring to serve in the naval service while pregnant in order that possible conflicts between the role of maintaining the Navy's posture of readiness and mobility and the role of parenthood are fully understood. (2) A pregnant servicewoman's commanding officer has responsibility for counselling the servicewoman once pregnancy has been confirmed. Counselors will discuss military entitlements to maternity care while on active duty (references (a) and (b)). The commanding officer should explain Navy policy on world-wide assignability which requires certain servicemembers to sign a page 13 appointing a guardian. Pregnant servicewomen ordered to overseas duty should be counselled concerning the decision to command sponsor/non-command sponsor their dependent per MILPERSMAN Article 1810550. (3) Servicewomen should be advised that requests for separation will not normally be approved. In those cases where extenuating circumstances exist, requests for separation should be submitted with adequate lead time (prior to the 20th week of pregnancy) to allow appropriate separation dates to be determined per Article 3620220 of reference (a). Pregnant servicewomen requesting separation will be counselled on the limited medical benefits available after separation. (4) Command counselling must be documented and recorded by service record entries. c. Work Reassignment. The commanding officer, with the health care provider and the cognizant occupational health professional, shall determine if any environmental hazards or toxins exist which may require work reassignment of the servicewoman, within the command, for the duration of the pregnancy. In cases where symptoms such as sudden lightheadedness, dizziness, nausea, easy fatiguablility, or loss of consciousness may impair performance, the servicewoman shall not be assigned to duties where she is a hazard to herself or others. Diving duty is hazardous and carries and increased hyperbaric risk to the fetus; therefore, diving during pregnancy is prohibited. If there is a question regarding assignment in these cases, the health care provider should be consulted. d. General Limitations. After confirmation of pregnancy, a pregnant servicewoman: (1) Shall be exempt from: (a) The regular physical training (PT) program of her unit. However, she shall be counselled and encouraged to participate in an approved American College of Obstetricians and Gynecologists (ACOG) exercise program, unless exempted by her health care provider for medical reasons. This program shall be made available through each military treatment facility providing prenatal care. (COM NAVMEDCOM will ensure that documentation for conducting this exercise program is provided to military treatment facilities.) (b) Physical readiness testing (PRT) during pregnancy and for six months following delivery. (c) Exposure to chemical or toxic agents and/or environmental hazards that are determined unsafe by the cognizant occupational health professional or the health care provider. (d) Standing at parade rest or attention for longer the 15 minutes. (e) All routine immunizations except tetanus-diphtheria unless clinically indicated. (f) Participation in weapons training, swimming qualifications, drown-proofing, and any other physical training requirements that may affect the health of the servicewoman and/or the fetus. (2) May be allowed to work shifts. (3) May be exposed to radio-frequency (RF) radiation 300Mhz and up to the same limits allowed in the non-pregnant state. The current limits allow for a whole-body Specific-Absorption Rate (SAR) not to exceed 0.4 W/kg when averaged over any six (6) minute period or a field strength measurement of 1mW/cm2. (4) May be exposed to ionizing radiation, but these exposures should be as limited as possible. The exposure should not exceed 0.5 rem (0.005 Sievert) during the entire gestation. Efforts should be made to avoid substantial variation above the uniform monthly exposure rate that would satisfy this limiting value. e. Specific Limitations. During the last three months of pregnancy (weeks 28 and beyond) the servicewoman shall be: (1) Allowed to rest 20 minutes every four hours (sitting in a chair with feet up is acceptable). (2) Limited to a forty hour work week. The forty hours may be distributed among any seven day period, but hours are defined by presence at servicewoman's duty station, and not type of work performed. Pregnancy does not remove a servicewoman from watchstanding responsibilities, but all hours shall count as part of the forty hour per week limitation. In instances where the unit work week and/or watchstanding requirements exceed forty hours, the commanding officer, in consultation with the health care provider and the occupational health professional, must be informed and approve, on a case-by-case basis, extension of the servicewoman's work week beyond forty hours. The servicewoman may request a work waiver to extend her hours beyond the stated forty hour week, if she is physically capable and her attending physician concurs. 102. Medical Considerations of Work Assignment and Training a. General. The commanding officer, in consultation with the health care provider and the occupational health professional (where appropriate), must determine whether or not the servicewoman requires a work reassignment. This may include complete reassignment to a different work environment or restriction(s) from performing specific types of tasks. b. Recommendations for Duty. In an uncomplicated pregnancy of a physically fit, trained servicewoman, working in a safe environment, there is probably little need for restriction of duty. c. Restrictions. These fall into four categories: (1) Medical. High blood pressure, bleeding, multiple pregnancy, or other indications as identified by the servicewoman's health care provider. (2) Environmental. Exposure to known toxins or hazardous conditions as determined by the appropriate occupational health professional. (3) Ergonomic. Instances where there may be no obvious medical contradictions but where individual's physical configuration and/or abilities preclude her from continuing with specific activities (such as lying in a prone position for weapons qualifications, diving duty, certain duty aboard ships, etc.) or where nausea or fatiguability would be hazardous to the servicewoman, the unborn child, and other servicemembers of the unit (e.g., air controller duties). (4) Other. Areas of questionably harmful effects such as nuclear, biological, and chemical (NBC) training, a regular unit physical training program, certain unit qualification tests or hands-on elements of skills qualification tests, potentially harmful environmental conditions, etc. 103. Administration a. Assignments. COMNAVMILPERSCOM shall limit overseas assignment of pregnant servicewoman as feasible, consistent with manning and readiness considerations. Based on medical considerations, no servicewoman may be assigned overseas or travel overseas after the beginning of the 28th week of pregnancy. Suitability screening for overseas duty, if properly conducted under procedures outlined in the TRANSMAN, assures that the assignment and transfer of pregnant servicewomen, officer and enlisted, conform with the following guidelines. (1) To an Overseas Duty Station/Geographically Isolated Duty Station. Servicewomen assigned to duty ashore in the 48 contiguous states, who are otherwise eligible for duty Outside Continental United States (OCONUS), and have not reached their 28th week of pregnancy, may be assigned for duty at an overseas installation except when any of the following conditions exist: (a) Adequate civilian/military medical facilities with obstetrical capabilities (meeting or equivalent to ACOG guidelines to provide care as required by reference (c)) are not available. (b) Servicewoman intends to place infant for adoption. In these cases the servicewoman will not be eligible for overseas/isolated duty until six months post-delivery. (c) Base or alternate civilian housing is not available. (2) Continental United States (CONUS). Servicewomen may be assigned in CONUS without restriction provided they do not have to fly after the 28th week of pregnancy. They will not be transferred to units that are deploying during the period from the 20th week of pregnancy through four months after the servicewoman's expected date of delivery. b. Specific Assignments (1) Initial Training. Servicewomen with pregnancies that existed prior to entrance (EPTE) or certified during initial training (e.g., recruit training or officer candidate school (OCS)) shall be discharged as unqualified for military service per Article 3810170 of reference (a). When certified as EPTE, the members shall be discharged without maternity benefits. The initial permanent duty station has the authority to discharge pregnant servicewomen when it is medically determined the they became pregnant during initial training. Discharged servicewomen shall not be prohibited from applying for reenlistment when no longer pregnant provided they are eligible for reenlistment in accordance with current directives. (2) Shipboard (a) The commanding officer in consultation with the health care provider and the appropriate occupational health professional shall decide whether the individual may safely continue in her shipboard assigned duties. This decision will be based on the servicewoman's condition and environmental toxins or hazards within the individual's workplace. (b) A pregnant servicwoman shall not remain aboard ship if the time for medical evacuation of the member to a treatment facility capable of evaluating and stabilizing obstetric emergencies is greater the 3 hours. (c) For enlisted servicewomen, commanding officers shall ensure that the enlisted availability report includes the date the pregnant servicewoman will be in her 20th week of pregnancy, and in the case of deploying units, the date of deployment. The servicewoman shall not remain on board beyond her 20th week of pregnancy. (d) Shipboard assignments are deferred up to a period of four months following delivery unless the servicewoman volunteers (waivers) for an earlier rotation. This time is meant to allow the delivered servicewoman time to regain her physical strength and stamina in order to perform the duties of her rate/rank. This does not preclude the stated six month waiver from physical readiness test participation, per paragraph 101d (1) (b). (3) Aviation Squadron (a) Pregnancy is considered disqualifying for designated flight status personnel including aircontrollers, however waivers may be requested up to the beginning of the third trimester. Flight personnel may be waived to Transport, Maritime, or Helo type aircraft with a cabin altitude less than 10,000 feet. Designated Naval Aviators (DNA) are waivered to Service Groups III (SG III) only. Pregnancy must be uncomplicated. No A-3 flights will be authorized. A local board of flight surgeons (LBFS), with the addition of a specialist in OB/GYN, must be held prior to any waiver request by the command. When LBFS has recommended waiver, an up chit may be issued at that time while awaiting passage of the waiver through channels. Maximum duration of this LBFS authorized up chit is 60 days. Notify Naval Aerospace Medical Institute (NAMI) Code 42 upon termination of pregnancy. Very close flight surgeon follow-up is mandatory. Ergonomic factors must be observed and flight status altered if the member cannot safely perform her duties due to the confines of her aircraft. (b) Aircontrollers may work up to the 28th week of pregnancy. From the 28th week and beyond, they may work in an administrative capacity only. Additionally, due to the building constraints that hamper medical evacuation, pregnant aircontrollers will normally be restricted from tower duties after their 27th week of pregnancy. (c) Servicewomen who become pregnant while assigned to sea duty aviation squadrons due for deployment, should be reassigned to a squadron not scheduled for deployment from the 20th week of pregnancy through recuperative period. (d) Aviation Waiver. Commanding officers of aviation crew or aircontrollers should submit waiver requests to OP-59 and NMPC-43B via Naval Aerospace Medical Institute (NAMI Code 42). (4) From and Within An Overseas Area (a) Servicewomen who are pregnant at the time of transfer will not be assigned to mandatory unaccompanied overseas duty stations, geographic locations that require the use of government quarters, nor areas that have inadequate OB/GYN facilities. Pregnant servicewomen will be deferred from overseas duty if they are in an advanced stage of pregnancy (greater than 28 weeks). (b) Servicewomen deferred from overseas transfer due to pregnancy will have their PRD adjusted to remain at their current duty station until 60 days following delivery. If conditions exist at their current duty station which preclude this extension, the servicewoman will be assigned Temporary Duty to another command until 60 days following delivery. At their adjusted PRD they will be assigned in accordance with the normal sea/shore rotation pattern of their rating. (c) Pregnant servicewomen stationed at an overseas duty station with adequate OB/GYN care and available housing (government or community) will remain at their current duty station. Pregnant servicewomen stationed at an overseas duty station without available housing (government or community) or adequate OB/GYN care, will be reassigned prior to their 20th week of pregnancy. (5) Reporting or Assigned as a Student (a) Assignment of a pregnant servicewoman will be handled on a case-by-case basis by her commanding officer. Consideration must be made for the course content and the limitations discussed in paragraphs 101c through 102. Additionally, the pregnant servicwoman will not be assigned to a school if her projected delivery date or recuperative period will occur during the course of instruction. (b) If a servicwoman becomes pregnant during training, the commanding officer of the training command will determine if she can complete her training, based on the discussion above. When disenrollment is required, it will be necessary to determine when training can be terminated. If possible, training will be terminated at a point where it will be academically feasible to reenter the training at a later date without repeating previouslycompleted portions of training. Based on this information and the projected delivery date, the commanding officer of the training command will determine the disenrollment date. (c) If disenrolled, the pregnant servicewoman will be returned to her parent command until fully recovered. If under Permanent Change of Station orders, final disposition will be determined by NMPC-4. (d) After returning to full duty, a servicewoman disenrolled for pregnancy will be afforded the opportunity to complete her training, consistent with manning and readiness conditions. Commander, Naval Education and Training will determine if enrollment will be necessary for the entire course of instruction or only for the portion lost as a result of disenrollment for pregnancy. c. Waivers (1) General. A waiver procedure has been established for use in unique circumstances. A servicewoman's commanding officer, if the circumstances warrant, may request a waiver on behalf of a servicewoman. See paragraph 202 under this instruction for details. (2) Aviation Waiver. See paragraph 103b (3) (c). d. Billeting. Commanding officers may, on a case by case basis, authorize pregnant servicewomen to move from barracks to the civilian community and receive appropriate allowances upon recommendation of medical and social work staff. e. Conduct and Discipline. Pregnant servicewomen have the same rights and responsibilities and are subject to the same administrative and disciplinary actions, as all other Naval personnel. An active duty servicewoman under court-martial charges or sentence of court-martial, who is certified by a military treatment facility physician as pregnant, may be discharged only with the written consent of the officer exercising general court-martial jurisdiction over her. f. Performance Evaluation. Commanding officers shall ensure that pregnant servicewomen are not adversely evaluated or receive adverse fitness reports as a consequence of pregnancy. Weight standards exceeded during pregnancy are not cause for adverse fitness reports or evaluations. Pregnant servicewomen and those who have recently delivered, who are otherwise fully qualified for and desire reenlistment, but who exceed acceptable weight standards of article 15-19 of reference (e), will be extended for the maximum of up to six months after delivery. g. Uniform. The proper wearing of the uniform during pregnancy is the concern and responsibility of the servicewoman and shall be addressed by the unit commanding officer. The maternity uniform is mandatory for all pregnant servicewomen in the Navy when a uniform is prescribed and regular uniforms no longer fit. This uniform, when worn, shall be labeled as a certified authorized naval garment and, as such, is the only style permitted to be worn with other naval accouterments. The outergarments (sweater, raincoat, overcoat, peacoat, and reefer) may be worn unbuttoned when the garment no longer fits properly buttoned. h. Maternity Care After Separation. Pregnant servicewomen may request separation from active duty. The information given to them, about continued maternity care at Government expense, usually plays a decisive role in making their decision. Thus, it is imperative that they fully understand the following information. Under the law, neither the military departments, CHAMPUS, nor the Veterans Administration has authority to pay civilian maternity care expenses for former servicewomen who separate from active duty while they are pregnant regardless of the circumstances requiring the use of civilian facilities. A former servicewoman loses her entitlement to all civilian maternity care at military expense upon receipt of discharge certificate (see Article 3620320 of reference (a) for effective time of discharge). (1) The Uniformed Services Voluntary Insurance Policy (90 day) medical insurance policy available to separating servicewomen will not cover pre-existing conditions such as pregnancy. This is also true of virtually all medical insurance programs in the private sector. Because of this, the service secretaries (under special administrative authority) allow former servicewomen, who separate under honorable conditions because of pregnancy, to receive maternity care for that pregnancy, up to 6 weeks following delivery, only in Armed Forces medical treatment facilities, on a space available basis. This care is available if: (a) The servicewoman presents documented evidence which reflects that a physical examination, given at an Uniformed Services Medical Treatment Facility, (USMTF) demonstrates that she was pregnant prior to her separation from active duty; and (b) The USMTF to which she applies for care has the capability of providing maternity care. Many USMTF's cannot provide maternity care. A pregnant servicewoman who elects to leave the service must first consider the distance between her home and the nearest USMTF which does have maternity care capability. She must consider the possibilities of premature delivery or other emergency maternity care needs. These factors could unexpectedly force her to use a civilian source of care. Should that happen, neither the military departments, CHAMPUS, nor the Veterans Administration has the authority to pay civilian maternity care expenses, regardless of the circumstances necessitating their use for either the servicewoman or the servicewoman's newborn infant. The servicewoman should be made aware that if the newborn infant requires care beyond that which is available at the USMTF, it may be necessary to transfer the infant to a civilian source of care (e.g., neonatal care) and these expenses will be the servicewoman's personal financial responsibility. However, every effort will be made to send this infant to a federal medical institution. (c) Before deciding to accept a discharge or resign from the service, a pregnant servicewoman should contact the Commanding Officer of the Uniformed Services Medical Treatment Facility she plans to use to determine if: (1) The facility provides maternity care; (2) The facility is close enough to her planned place of residence to provide her assurance that, barring emergency requirements, she can reach it expeditiously at time of birth; (3) The facility's workload will permit acceptance of her case. i. Medical Examination and Diagnosis for Separation (1) An examination for pregnancy will be conducted as part of the thorough medical examination required in article 15-56 of reference (e). The statement the servicewoman is required to read and attest an understanding of assures that the examining officer will be apprised if the servicewoman thinks that she may be pregnant. When such an examination results in the determination of pregnancy, no additional medical examination is required prior to separation provided there is no change in the woman's medical condition other than her pregnancy. The diagnosis will be certified by a physician on duty at a Uniformed Services Medical Treatment Facility as soon as possible. This does not preclude observation of the servicewoman for a reasonable period of time in which to ensure that the diagnosis is correct. In establishing the diagnosis, the physician may utilize biological or other tests for pregnancy without cost to the servicewoman. j. Evacuation of Pregnant Servicewomen. If noncombatant evacuation is ordered, all pregnant servicewomen who have reached the 20th week of pregnancy will be evacuated as noncombatants. This also applies to other pregnant servicewomen, on an individual basis, assigned to an area from which noncombatants are evacuated. The following applies to pregnant servicewomen who have not reached the 20th week of pregnancy: (1) The area commander will make the decision to evacuate servicewomen in the earlier (less than 20 weeks) stages of pregnancy. The area commander will consult with available medical authority and base a decision on: (a) Ability of the pregnant servicewoman to perform in her specialty. (b) Capability of field medical (or other support unit) to provide emergency obstetrical care. (c) Requirement for the servicewoman's duties. (d) Nearness of the hostilities. (e) Welfare of the unborn child. (2) Medical evacuation methods will not be used for pregnant servicewomen unless directed by a medical officer. (3) Pregnant servicewomen evacuated will be reported to and reassigned by COMNAVMILPERSCOM (NMPC-4). 104. Convalescent Leave. Post delivery convalescent leave of six weeks (42 days) will normally be granted by the servicewoman's commanding officer under the following: a. The servicewoman's commanding officer (upon advice of the attending physician), Commanding Officers of the USMTF, or Office of Medical Affairs (OMA) (for persons hospitalized in civilian facilities within their respective areas of authority), may grant convalescent leave to naval servicewomen following delivery provided: (1) Such convalescent leave is limited to a maximum of 42 days following any uncomplicated vaginal delivery or cesarean section. (2) The servicewoman is not awaiting disciplinary action or separation from the service for medical or administrative reasons. (3) The medical officer in charge certifies that the patient is not fit for duty, will not need hospital treatment during the contemplated leave period, and that such leave will not delay the final disposition of the patient. b. When considered necessary by the attending physician and approved on an individual basis by the commander of the respective geographic naval medical command, convalescent leave in excess of 42 days may be granted. Due to the time involved, this individual approval authority may not be redelegated to hospital commanding officers. The servicewoman's permanent command must be notified of such extensions (Article 3020360 of reference (a) refers). 105. Breast-feeding. Servicewomen wishing to breast-feed their infants may do so during times allotted for breaks or meals. Breast-feeding is not a reason for granting excessive time for meals or from work. Requests to breast-feed infants during duty hours should be handled on a case-by-case basis. CHAPTER TWO SERVICEWOMAN 201. Responsibilities. The individual servicewoman is responsible for: a. Planning her pregnancy to allow her to meet both her family and military obligation. b. Seeking confirmation of pregnancy at a military medical treatment facility. c. Notifying her commanding officer or officer in charge of her pregnancy. d. Performing her military duties within the limits established by her condition. e. Complying with worksite and task-related safety and health recommendations, made by appropriate occupational health professionals, including the use of personal protective equipment. 202. Waiver Request. Requests for a waiver of pregnancy policy restrictions shall be promptly to Commander, Naval Military Personnel Command (COMNAVMILPERSCOM) (NMPC-4) for officers and rated enlisted personnel, or the Enlisted Personnel Management Center (EPMAC) in the case of non-designated SN/AN/FN. The appropriate COMNAVMILPERSCOM (NMPC-4) detailer will screen the request and make the final determination regarding assignment eligibility. A medical waiver request should contain all information required by COMNAVMILPERSCOM along with the following items: a. Narrative of condition including number of weeks of gestation, present condition, special treatment requirements, and any anticipated future requirements other than normal delivery. b. Results of specialty consultation that include the medical officer's estimate of the servicewoman's ability to perform assigned duties, and when such duties should be terminated prior to the expected date of delivery. c. If the member is due to be stationed overseas, determination of the available medical care must be evaluated. This includes the facility's ability to treat the servicewoman for prenatal care, delivery, and postnatal care for servicewoman and infant. 203. Obstetrical Care a. In Vicinity of Servicewoman's Command. When pregnant servicewomen remain at their duty stations, maternity care will be provided at the USMTF designated, provided it has obstetrical-gynecological (OB-GYN) capability and the servicewoman resides in the facility's inpatient area. If that USMTF does not have OB-GYN capability and there is no other USMTF with OB-GYN capability serving her residence area, she may choose to deliver in a civilian hospital closer to her residence, or travel to the nearest or most accessible USMTF for delivery. See references (b) and (f) for procedures relative to receipt of payment for civilian care. Upon discharge from either the military or civilian inpatient facility following delivery, the servicewoman will be granted convalescent leave based on specific medical indications. Article 3020360 of reference (a) and paragraph 104 of this instruction provide guidance for the granting of convalescent leave. b. While in a Leave Status. If a servicewoman requests leave to return to her home (or other appropriate place) for the birth or other maternity care, and there is no USMTF serving the area of her leave address (or she does not intend to use the USMTF), the servicewoman shall obtain authorization under reference (f) if the Government is to assume financial responsibility for such care. (1) Prior to approving such leave, the servicewoman's commanding officer shall ensure that the servicewoman has received counseling, to include the local health benefits advisor (HBA) with regard to prenatal and postnatal care available in her leave area and the command or family services expert with regard to parental and financial responsibilities. Additionally, the servicewoman will be advised that she cannot report to an installation and request attachment solely to preclude continued loss of leave. Leave status can only be terminated when determined medically necessary by a physician. This normally should occur at the time of confinement for delivery. (2) When a servicewoman has been granted leave to cover the period of an imminent delivery, the servicewoman should request a copy of her complete prenatal care records from the attending physician. The attending physician should note in the record whether the servicewoman is medically cleared to travel. The servicewoman will obtain from the Patient's Administration Department, a statement bearing the name of the USMTF [may be an office of medical affairs (OMA)] having medical responsibility for the geographic area of the patient's leave address. If the servicewoman is receiving prenatal care from other than a USMTF, she should avail herself of the services of the nearest HBA to effect the aforestated services. This statement should be attached to the approved leave request. (3) Upon arrival at the designated leave address, servicewomen shall notify the USMTF indicated on the statement attached to their leave request. A determination will be made by that USMTF whether the servicewoman's condition can be adequately treated and her leave address falls within their inpatient area. If the local USMTF cannot meet the medical needs of the patient or the patient's leave address is outside the USMTF's inpatient area, the servicewoman will be given the opportunity to choose to deliver in a civilian hospital closer to her leave address or travel to the most accessible USMTF [under reference (c)] for maternity care. (4) When civilian medical care will be utilized, the member must notify the USMTF listed on the statement of any admission to the civilian facility. (a) Civilian maternity care for the servicewoman includes all charges for the servicewoman and the newborn as long as the mother remains hospitalized. Bills shall be submitted to the appropriate OMA per reference (f). (b) If the infant must remain in or is transferred to a civilian hospital after discharge of the mother, the infant's admission or transfer costs shall be cost-shared under the Civilian Health and Medical Program of Uniformed Services (CHAMPUS) under reference (f). (5) Upon discharge from the civilian hospital following delivery, the mother will be granted convalescent leave (by the USMTF listed on the statement attached to her leave request) or by the cognizant OMA following paragraph 104. The period, if any, between expiration of convalescent leave and the servicewoman's return to her parent organization is chargeable as ordinary leave. 204. Infants Placed For Adoption. Initial guidance and assistance for placing infants for adoption can be obtained from the local Navy Legal Support Office and the local Family Service Center. Servicewomen intending to place their infants for adoption will meet with the appropriate legal counsel and placement agencies to ensure specific state requirements are followed. Pregnant servicewomen are not eligible for OUTCONUS assignments until delivery and adoption requirements are completed. 205. Convalescent Leave a. A period of authorized absence granted for an active duty servicewoman under medical care and not fit for duty, may be granted by the servicewoman's commanding officer or the hospital's commanding officer following delivery. The length of convalescent leave will normally be 42 days following an uncomplicated vaginal delivery or cesarean section. The servicewoman may terminate such leave early with the attending physician's approval and making provisions for adequate child care. b. It is a responsibility of the servicewoman to report any complications or medical problems that she experienced during convalescent leave to her appropriate command to ensure the granting of appropriate convalescent leave. Upon return from convalescent leave: (1) One copy of leave papers of officers, bearing all endorsements, shall be forwarded to NMPC-4. (2) An entry shall be made on the administrative remarks page (page 13 for Navy personnel) of the service records of enlisted personnel that convalescent leave was granted and showing dates of departure and return. CHAPTER THREE HEALTH CARE PROVIDER 301. Responsibilities. a. Upon confirmation of pregnancy by a health care provider, written notification of the servicewoman's condition will be provided to the servicewoman's commanding officer per reference (b). The health care provider must ensure the privacy of the servicewoman while at the same time safeguarding both her welfare and that of her unborn child. b. When pregnancy is confirmed, there are many related matters, not strictly medical, about which the health care provider is called upon to aid in decision making. Each health care provider, with responsibility for pregnancy confirmation or prenatal care, should be familiar with the administrative and command requirements relating to pregnant servicewomen. The servicewoman's health care provider must provide timely guidance on work restrictions and the most effective job utilization of the pregnant servicewoman without undue stress to her or her unborn child. Additionally, the health care provider must monitor the health of the servicewoman to determine if additional convalescent leave is warranted. 302. Light Duty. Article 3810170 of reference (a) provides for placement of pregnant servicewomen in a light duty status with subsequent assignment to sick in quarters status (here designated as Quarters-OB) prior to hospitalization for delivery. Accordingly, light duty may be recommended to a pregnant servicewoman's commanding officer any time a health care provider determines that it is needed. Unless prescribed by the attending medical officer earlier in the pregnancy due to other than normal circumstances, pregnant servicewomen are usually placed in a light duty status between the 36th to the 38th week of pregnancy . Additionally, light duty may be prescribed for a maximum of 2 weeks for those servicewomen having completed convalescent leave, who are ready to report to the command, but can only work part time. 303. Problem Pregnancy. a. General. Some pregnant servicewomen will require significant amounts of time away from the work environments; e.g., past history of multi-problem pregnancy, bleeding or threatened abortions. In these instances, it is not unusual for the attending health care provider to order the servicewoman to bedrest for extended periods, or until delivery. The loss of such a servicewoman may adversely impact upon the command. In these instances the following disposition alternatives may be utilized: (1) Quarters-OB Status. See paragraph 303b. (2) Medical Holding Company. This may be utilized for those requiring extraordinary time in a Quarters-OB status. Placement as TEMDU in a medical holding company by a USMTF with an affiliated Medical Holding Company enables the parent command to gain relief for the loss of the servicewoman. Placement in this status should be done in consultation with the servicewoman's command. (The time limitations for remaining in a medical holding company are waived for pregnant servicewomen.) Once admitted to a medical holding company, the servicewoman should be assigned duties commensurate with the physical limitations directed by her attending health care provider. (3) Admission to an MTF. In those instances deemed appropriate and in keeping with utilization review standards, a servicewoman living in the barracks who requires extended bedrest may be admitted to an MTF. (4) Limited Duty Board. Some servicewomen may require a significant alteration in work assignment which may adversely impact the command. A limited duty board allows the command to gain a replacement. b. Quarters-OB (1) Policy. Pregnant servicewomen requiring extended bedrest who reside outside the barracks and who must be seen by their attending health care provider at least weekly may be placed in a Quarters-OB status at home. The attending health care provider must specifically certify that Quarters-OB is prescribed. (Consult the patient administration officer of any naval MTF for guidance.) A pregnant servicewoman will not be placed in a Quarters-OB status solely on the basis of her pregnancy, i.e., no complications or extenuating circumstances. The medical condition of the patient must dictate the length of time the patient should be allowed to remain in a Quarters-OB status. Accordingly, the normal 72-hour time limit for sick in quarters patients is waived for Quarters-OB patients. Granting this status should be reserved for those instances when, in the opinion of the health care provider responsible for providing prenatal care: (a) The servicewoman has become disabled. (b) There are complications present that would preclude any type of duty responsibilities and delivery is imminent. (c) There are complications or conditions caused by or directly related to the pregnancy (e.g., excessive vomiting, hypertension, or multiple pregnancy), although not precluding all duty responsibilities, could potentially lead to an adverse obstetrical outcome if the member was in a duty status. (2) Procedures. To place a patient in a Quarters-OB status, the health care provider shall record on the DD Form 689, Individual Sick Slip, the expected duration of Quarters-OB and if the period is to exceed 72 hours, the chief of the professional service or hospital commanding officer must sign the DD Form 689. When a pregnant servicewoman is placed in this status, it must also be noted on her Consultation Sheet (SF 513) and placed in her record. The reputation of the servicewoman and the credibility of medical care usually require an explanation to the servicewoman's commanding officer by the attending health care provider when complications of pregnancy are managed by a long-term (72 hours or longer) Quarters-OB status. 304. Hospitalization a. General. When it becomes necessary to hospitalize a pregnant servicewoman, because of complications or the onset of labor, the USMTF Commanding Officer will notify the service-member's commanding officer, citing the medical indication on which the decision is based (see reference (b) for notification requirements). Further information regarding hospitalization of pregnant servicewomen may be found in paragraph 203 of this instruction. 305. Postnatal Care a. Sick in Quarters. Since all pregnancy terminations do not require the same length of time before the servicewoman can resume her duties, the physician providing postnatal care may place a servicewoman sick in quarters when neither light duty, hospitalization, nor convalescent leave is indicated and the servicewoman may be capable of returning to full duty within, at most, a 72-hour period. Article 3020380 of reference (a) states that a servicewoman is in this status when excused from duty for treatment or medically directed self-treatment. The servicewoman may be in the home, barracks, or other non-hospital facilities (hotel, motel, occupying beds in dispensaries, etc.). At the discretion of the attending medical officer, such servicewomen may be placed sick in quarters after return to duty the same as any other servicewoman. The fact that she may have recently returned from convalescent leave shall not be cause for refusal to place a servicewoman sick in quarters. 306. Termination of Pregnancy a. General. Department of Defense (DoD) funds are not available for the elective termination of pregnancy except where the life of the mother would be endangered if the fetus were carried to term. b. Abortions (1) General (a) The performance of abortions at naval MTFs shall conform with the provisions of proposed SECNAVINST 6300., Subj: Navy Abortion Policy. (b) The use of appropriated funds to perform abortions is prohibited except where the life of the mother would be endangered if the fetus were carried to term. This limitation does not apply to medical procedures necessary for the termination of an ectopic pregnancy. (2) At Civilian Facilities. When available and adequate, civilian facilities will be used at the servicewoman's own expense. Except when a servicewoman must be admitted, ordinary leave will be granted in order to have the procedure accomplished. Any subsequent treatment or hospitalization required as a result of an abortion at a civilian facility will be managed as any other illness or disability under references (b) or (f), as appropriate. (3) Convalescent Leave. The requirements for convalescent leave shall be determined by the attending physician on an individual basis. 307. Weight Standards. Weight standards exceeded during pregnancy are not cause for adverse fitness reports or evaluations. Pregnant servicewomen and servicewomen who have recently delivered who are otherwise fully qualified for and desire reenlistment, but who exceed the acceptable weight standards of article 15-19 of reference (e), will be extended for the minimum period which will allow for birth of the child plus six months. 308. Pregnant Brig Prisoners. The care and management of pregnant servicewomen prisoners confined to a brig shall conform to the requirements of this instruction except that convalescent leave cannot be authorized. Pregnancy per se does not preclude confinement in a brig as long as appropriate prenatal care is provided and there is a medical treatment facility near the brig which can provide for labor, delivery, and the management of obstetric emergencies. 309. Breast-feeding. Mothers electing to breast feed their infants may do so during times allotted for breaks or meals. Breast-feeding is not a reason to grant excessive time from work. Request to breast-feed infants during duty hours should be submitted to the current command. CHAPTER FOUR OCCUPATIONAL HEALTH PROFESSIONAL 401. Responsibilities. a. General. The cognizant health professional is responsible for providing consultation to commanding officers to assist them in fulfilling their professional responsibilities to provide a safe and healthy workplace. This may include recommendations to guard the health of pregnant servicewomen and their unborn child. Depending on the circumstances and information required, the appropriate occupational health professional may be: an occupational physician, industrial hygienist, occupational health nurse, audiologist, radiation health officer, toxicologist, or environmental health officer. b. Naval Medical Commands. Onsite occupational health consultations are provided by the supporting Commander, Naval Medical Command USMTF. Additional support is available from the Navy Geographic Commands, the Navy Environmental Health Center, or the Navy Environmental and Preventive Medicine Units. c. NAVENVIRHLTHCEN. The Navy Environmental Health Center (NAVENVIRHLTHCEN) will develop a list of potential reproductive hazards based on professional review of the current literature and analysis of available data, to be updated January of each year. Where feasible, this list will include recommended exposure-limits. A provisional NAVENVIRHLTHCEN REPRODUCTIVE HAZARD LIST-88 is listed in Appendix (A). NAVENVIRHLTHCEN will provide guidance to medical departments on criteria for requesting occupational health consultation and will also provide generic reproductive hazard guidance on request or when indicated. d. COMNAVMEDCOM Industrial Hygienists. At the time of a baseline industrial hygiene survey, and during the periodic survey updates, the presence of possible reproductive hazards will be evaluated including potential exposure to agents on the NAVENVIRHLTHCEN list. Any positive findings will be brought to the attention of the commanding officer or designated safety/health official. e. TYCOM/Afloat Industrial Hygiene Officer (IHO). IHOs having cognizance over ships with assigned females will periodically evaluate the presence of shipboard reproductive hazards and make recommendations to the commanding officer and the medical department representative. The medical department representative should request an evaluation when interpretation of individual and group exposure data involving pregnant servicewomen is needed. 402. Approach. A three phased approach is necessary for optimal feto-maternal health promotion: Phase I: Prepregnancy/Preventive Phase II: Early Pregnancy/Risk Management Phase III: Pregnancy/Job Modification 403. Prepregnancy/Preventive. Naval personnel will be educated on their responsibilities in the prevention of adverse reproductive outcomes including worksite precautions as well as the reduction of alcohol intake and smoking cessation, using media developed by the Navy Health Sciences Education and Training Command in consultation with the Navy Environmental Health Center. The baseline industrial hygiene survey required by reference (g) for each Navy worksite will be reviewed periodically for possible reproductive hazards. Recommendations will be provided to Naval personnel requesting guidance prior to planned conception. 404. Early Pregnancy/Risk Management. The servicewoman should report as soon as possible to the supporting medical facility for assistance in evaluating her condition when pregnancy is suspected. The servicewoman's command should ascertain whether her worksite has had an industrial hygiene survey. Consultation with an occupational health professional, for evaluation of the survey, is available. Temporary removal of the pregnant servicewoman from an industrial setting may be indicated if the setting has not had a recent industrial hygiene evaluation. Certain elements in the early pregnant servicewoman's medical history, by themselves or in conjunction with the pregnant servicewoman's occupational health consultation. The outline contained in Appendix B may be used to identify the need for consultation and preliminary job/worksite modification. 405. Pregnancy/Job Modification. Occupational health consultation may be indicated during the pregnancy for updated review of previous job or personal protective equipment qualification/certification and for work/worksite modification recommendations. Interdisciplinary cooperation between obstetrics, occupational health, and the servicewoman's command is absolutely essential to responsible matching of job requirements and individual performance capabilities of the pregnant servicewoman. In most instances the pregnant servicewoman will be able to complete most of the required tasks of her originally assigned position with only minor modifications usually affected because of ergonomic rather than toxin avoiding considerations. Where potential reproductive hazards are identified that warrant significant job modification or exclusion, the commanding officer or designated representative will be notified. APPENDIX A NEHC POTENTIAL REPRODUCTIVE HAZARD LIST-88 PRIVATE AGENT PROVISIONAL EXPOSURE LIMIT  ADDITIONAL GUIDANCE LEAD.050 mg/m3 maternal blood Pb (30 gm/100ml) CADMIUM.010 mg/m3 MERCURYinorganic.05 mg/m3 organic-alkyl.01 mg/m3non-detectable exposure best organic-aryl.05 mg/m3BENZENE1 ppm CHLOROPRENE1 ppm DBCP1 ppb CHLORDANE0.5 mg/m3 CARBON DISULFIDE10 ppmETHYLENE OXIDE1 ppmETHYLENE THIOUREA not yet determined GLYCOL ETHERS2-ME5 ppm 2-EE5 ppm ETHYLENEDIBROMIDE 1 mg/m3 PERCHLORETHYLENE50 ppmPCBs42 percent CL1.0 mg/m354 percent CL0.5 mg/m3VINYL CHLORIDE1 ppmCARBARYL5 mg/m3 HALOG. ANESTH. GAS 2 ppmNITROUS OXIDE50 ppm APPENDIX B OCCUPATIONAL REPRODUCTIVE QUESTIONNAIRE This questionnaire is designed to help Medical Department personnel identify pregnant servicewomen who require occupational health consultation, the priority of such consultation and the need for job modification and/or exclusion until such consultation has been effected. NAME____________________________________________________SS#_________________ RATE/RANK______________________________________________BSC_________________ SERVICEWOMAN: Please CHECK the best answer to the following questions: 1. How old are you? a. 18-30 ( ): b. 31-40 ( ): c. over 40 ( ): 2. What one term best describes your job? a. industrial ( ) b. clerical/admin/staff ( ) c. professional ( ) d. technical ( ) e. other ( ) 3. What one term best describes where you spend most of your workday? a. office ( ) b. shipboard ( ) c. shop ( ) d. outdoors ( ) e. other ( ) 4. Are you currently enrolled in a medical surveillance program? Yes ( ) No ( ) Dont know ( ) 5. Are you required to use personal protective equipment in the normal course of your job? Yes ( ) No ( ) 6. Are you pregnant now? a. Yes ( ) No ( ) Unsure ( ) b. How far? (1) first month ( ) (2) 3-8 wks ( ) (3) beyond 8 wks ( ) c. Have you had a positive UCG (urine pregnancy test)? a. Yes ( ) No ( ) d. Have you had a previous pregnancy? Yes ( ) No ( ) (1) # of normal liveborn children: ( ) (2) # of children with birth defects: ( ) (3) # of stillbirths: ( ) (4) # of miscarriages: ( ) 7. Do you work with any of the chemicals on the NEHC POTENTIAL REPRODUCTIVE HAZARDS LIST? Yes ( ) No ( ) Dont know ( ) MEDICAL DEPARTMENT: Complete the following: 8. Has she had a recorded occupational illness or injury in the past year? Yes ( ) No ( ) 9. a. Has her present job/worksite had a current industrial hygiene (IH) survey? Yes ( ) No ( ) b. Does the IH survey reveal exposure to any agent on the NEHC POTENTIAL REPRODUCTIVE HAZARDS LIST? Yes ( ) No ( ) c. Does the IH survey reveal any other reproductive hazards? Yes ( ) No ( ) 10. a. Is there Industrial Hygiene data listed in the medical record? Yes ( ) No ( ) b. Are there any exposures above the Permissible Exposure Limit (PEL)? Yes ( ) No ( ) 11. Any chemical spills at the servicewoman's worksite in the past year? Yes ( ) No ( ) 12. Any chronic illness that might complicate the pregnancy? Yes ( ) No ( ) 13. Does she regularly take any medications? Yes ( ) No ( ) 14. Any other medical conditions that might complicate the pregnancy? Yes ( ) No ( ) What?_______________________________ 15. Is there an up to date occupational history in the medical record? Yes ( ) No ( ) Directions: Qualitative evaluation of answers to the above questions will, in most cases, determine which cases may be a cause for concern. Occupational Health professionals supporting NAVMEDCOM MTF's or Navy Environmental Health Center are available to provide assistance in evaluating questionnaire responses. Specific questions or comments concerning the questionnaire should be directed to NEHC Code 03. APPENDIX C PREGNANCY NOTIFICATION TO COMMANDING OFFICER Suggested information to be included in Pregnancy Notification to Commanding Officer Date To: _______________________________________________________________________ Commanding Officer/Officer-in-charge From: _______________________________________________________________________ MTF/Physician Subj: _______________________________________________________________________ Member's Name _______________________________________________________________________ Social Security Number Ref: OPNAVINST 6000.1A This is to notify _________________________________ command of her pregnancy. Using current dating information, her Estimated Date of Confinement is _________________________. This would make her 20th week about ______________________ and her 28th week about ________________________. Pregnancy is a condition of several physiological changes which potentially require alterations in job function and hours. Please refer to OPNAVINST 6000.1A for guidelines. Certain unforeseen conditions may arise which warrant specific medical interaction. These conditions may require further constraints and are handled on a case-by-case basis. Ultrasound Measurements in Pregnancy These measurements (in mm) represent the mean values for each gestational age week. Gestational Age (Weeks)Sac SizeCRLBPDFemur LengthHead CircumferenceAbdominal Circumference43566147278829159332110311141125121870561371251184691428159881153218111931635211241051739241371171842271501291946301621412049331751522152361871642255391981752358422101862461442211972564472322082667492422192769522522292872542622402974562712503077592802603179612882703282632962803384653042903486673112993588683183093690703243183792723303273894733353363995753403454097763443544198783483624210079351371 Gestational Age is in weeks from the first day of the last menstrual period and assumes ovulation on day #14 of that cycle. Gestational sac size is based on the studies of Baltzer FR, et al: Am J Obstet Gynecol,146:973, 1983 BPD measurements are from outer to inner skull tables and are derived from Sabbagha RE and Hughey, Obstet Gynecol 52;402, 1978. Head circumference measurements are adapted from Hadlock FP, et al: AJR 138:649, 1982 Femur length measurements are adapted from Hadlock FP, et al: AJR 138, 875, 1982 Abdominal circumference measurements are adapted from Hadlock FP, et al, AJR 139:367, 1982 Gestational Age Calculator Find the 1st day of the last normal menstrual period (LMP). In the next column (EDC) is the corresponding estimated date of confinement (due date, or LMP plus 280 days). Julian DateLMPEDC11/110/721/210/831/310/941/410/1051/510/1161/610/1271/710/1381/810/1491/910/15101/1010/16111/1110/17121/1210/18131/1310/19141/1410/20151/1510/21161/1610/22171/1710/23181/1810/24191/1910/25201/2010/26211/2110/27221/2210/28231/2310/29241/2410/30251/2510/31261/2611/1271/2711/2281/2811/3291/2911/4301/3011/5311/3111/6322/111/7332/211/8342/311/9352/411/10362/511/11372/611/12382/711/13392/811/14402/911/15412/1011/16422/1111/17432/1211/18442/1311/19452/1411/20462/1511/21472/1611/22482/1711/23492/1811/24502/1911/25512/2011/26522/2111/27532/2211/28542/2311/29552/2411/30562/2512/1572/2612/2582/2712/3592/2812/4602/2912/5613/112/6623/212/7633/312/8643/412/9653/512/10663/612/11673/712/12683/812/13693/912/14703/1012/15713/1112/16723/1212/17733/1312/18743/1412/19753/1512/20763/1612/21773/1712/22783/1812/23793/1912/24803/2012/25813/2112/26823/2212/27833/2312/28843/2412/29853/2512/30863/2612/31873/271/1883/281/2893/291/3903/301/4913/311/5924/11/6934/21/7944/31/8954/41/9964/51/10974/61/11984/71/12994/81/131004/91/141014/101/151024/111/161034/121/171044/131/181054/141/191064/151/201074/161/211084/171/221094/181/231104/191/241114/201/251124/211/261134/221/271144/231/281154/241/291164/251/301174/261/311184/272/11194/282/21204/292/31214/302/41225/12/51235/22/61245/32/71255/42/81265/52/91275/62/101285/72/111295/82/121305/92/131315/102/141325/112/151335/122/161345/132/171355/142/181365/152/191375/162/201385/172/211395/182/221405/192/231415/202/241425/212/251435/222/261445/232/271455/242/281465/253/11475/263/21485/273/31495/283/41505/293/51515/303/61525/313/71536/13/81546/23/91556/33/101566/43/111576/53/121586/63/131596/73/141606/83/151616/93/161626/103/171636/113/181646/123/191656/133/201666/143/211676/153/221686/163/231696/173/241706/183/251716/193/261726/203/271736/213/281746/223/291756/233/301766/243/311776/254/11786/264/21796/274/31806/284/41816/294/51826/304/61837/14/71847/24/81857/34/91867/44/101877/54/111887/64/121897/74/131907/84/141917/94/151927/104/161937/114/171947/124/181957/134/191967/144/201977/154/211987/164/221997/174/232007/184/242017/194/252027/204/262037/214/272047/224/282057/234/292067/244/302077/255/12087/265/22097/275/32107/285/42117/295/52127/305/62137/315/72148/15/82158/25/92168/35/102178/45/112188/55/122198/65/132208/75/142218/85/152228/95/162238/105/172248/115/182258/125/192268/135/202278/145/212288/155/222298/165/232308/175/242318/185/252328/195/262338/205/272348/215/282358/225/292368/235/302378/245/312388/256/12398/266/22408/276/32418/286/42428/296/52438/306/62448/316/72459/16/82469/26/92479/36/102489/46/112499/56/122509/66/132519/76/142529/86/152539/96/162549/106/172559/116/182569/126/192579/136/202589/146/212599/156/222609/166/232619/176/242629/186/252639/196/262649/206/272659/216/282669/226/292679/236/302689/247/12699/257/22709/267/32719/277/42729/287/52739/297/62749/307/727510/17/827610/27/927710/37/1027810/47/1127910/57/1228010/67/1328110/77/1428210/87/1528310/97/1628410/107/1728510/117/1828610/127/1928710/137/2028810/147/2128910/157/2229010/167/2329110/177/2429210/187/2529310/197/2629410/207/2729510/217/2829610/227/2929710/237/3029810/247/3129910/258/130010/268/230110/278/330210/288/430310/298/530410/308/630510/318/730611/18/830711/28/930811/38/1030911/48/1131011/58/1231111/68/1331211/78/1431311/88/1531411/98/1631511/108/1731611/118/1831711/128/1931811/138/2031911/148/2132011/158/2232111/168/2332211/178/2432311/188/2532411/198/2632511/208/2732611/218/2832711/228/2932811/238/3032911/248/3133011/259/133111/269/233211/279/333311/289/433411/299/533511/309/633612/19/733712/29/833812/39/933912/49/1034012/59/1134112/69/1234212/79/1334312/89/1434412/99/1534512/109/1634612/119/1734712/129/1834812/139/1934912/149/2035012/159/2135112/169/2235212/179/2335312/189/2435412/199/2535512/209/2635612/219/2735712/229/2835812/239/2935912/249/3036012/2510/136112/2610/236212/2710/336312/2810/436412/2910/536512/3010/636612/3110/7 GYNECOLOGIC CONSULTATION Age: Grav: Temp: Allergies: DOB: Para: Pulse: Medications: Last Pap: AB: Resp: Smoking: LMP: Q____x____ BP: Alcohol: Contraception: Weight: Chief Complaint: History: Thyroid: Breasts: Abdomen: Pelvic: Impression: Plan: Menstrual Flow Record Year Name Phone Address Month12345678910111213141516171819202122232425262728293031Breast CheckJan.Feb.Mar.Apr.MayJun.Jul.Aug.Sep.Oct.Nov.Dec. Menstrual Flow Record Year Name Phone Address Month12345678910111213141516171819202122232425262728293031Breast CheckJan.Feb.Mar.Apr.MayJun.Jul.Aug.Sep.Oct.Nov.Dec. Menstrual Flow Record Year Name Phone Address Month12345678910111213141516171819202122232425262728293031Breast CheckJan.Feb.Mar.Apr.MayJun.Jul.Aug.Sep.Oct.Nov.Dec. Phone Numbers US Military Hospitals with OB-GYN Physicians Available for Consultation 
PRIVATEUnited States ArmyPRIVATEFort Belvoir, VADewitt U.S. Army Community HospitalOB-GYN Clinic(C) (703) 805-0808(DSN) 655-0808Labor & Delivery(C) (DSN)  PRIVATEFort Benning, GAMartin U.S. Army Community HospitalHospital(C) (706) 544-1209/1887(DSN) 784-1209Labor & Delivery(C) (706) 544-1621 (DSN) 784-1621 PRIVATEFort Bragg, NCWomack Army Medical CenterEmergency Room(C) (910) 432-1811(DSN) 432-1811Labor & Delivery(C) (910) 432-8426 (DSN) 239-8426 PRIVATEFort Campbell, KYBlanchfield U.S. Army Community HospitalOB-GYN Clinic(C) (502) 798-8151(DSN) 635-8151Labor & Delivery(C) (DSN) PRIVATEFort Carson, COEvans U.S. Army Community HospitalOB-GYN Clinic(C) (719) 526-7407/7456(DSN) 691-7407Labor & Delivery(C) (DSN)  PRIVATEFort Drumm, NYGuthrie Ambulatory Health Care clinicOB-GYN Clinic(C) (315) 772-4610-9868/4610(DSN) 341-4610Labor & Delivery(C) (DSN)  PRIVATEFort Gordon, GADD Eisenhower Army Medical CenterOB-GYN Clinic(C) (706) 787-7228/2921Labor & Delivery(C)  PRIVATEFort Hood, TXDarnell U.S. Army Community HospitalHospital -24 hour number(C) (254) 288-8000(DSN) 738-8000Labor & Delivery(C) (254) 288-8400 (DSN) 738-8400 PRIVATEFort Irwin, CAWeed U.S. Army Community HospitalOB-GYN Clinic(C) (760) 380-4048(DSN) 470-4048Labor & Delivery(C) (DSN)  PRIVATEFort Jackson, SCMoncrief U.S. Army Community HospitalHospital -24 hour number(C) (803) 751-2251(DSN) 734-2251Labor & Delivery(C) (DSN)  PRIVATEFort Knox, KYIreland U.S. Army Community HospitalOB-GYN Clinic(C) (502) 624-9196/9170(DSN) 464-9196Labor & Delivery(C) (DSN)  PRIVATEFort Leonard Wood, MOLeonard Wood U.S. Army Community HospitalOB-GYN Clinic(C) (573) 596-1770/1490(DSN) 581-1770Labor & Delivery(C) (DSN) PRIVATEFort Lewis, WAMadigan Army Medical CenterHospital -24 hour number(C) (235) 968-1110(DSN) 782-1110Labor & Delivery(C) (253) 968-1540 (DSN) 782-1540 PRIVATEFort Polk, LABayne-Jones U.S. Army Community HospitalOB-GYN Clinic(C) (318) 531-3705/3708(DSN) 863-3705/3708Labor & Delivery(C) (DSN)  PRIVATEFort Riley, KSIrwin U.S. Army Community HospitalHospital -24 hour number(C) (785) 239-3911(DSN) 856-3911Labor & Delivery(C) (785) 239-7164 (DSN) 856-7164 PRIVATEFort Sam Houston, TXBrooke Army Medical CenterOB-GYN Clinic(C) (210) 916-2525(DSN) 429-2525Labor & Delivery(C) (DSN)  PRIVATEFort Sill, OKReynolds U.S. Army Community HospitalOB-GYN Clinic(C) (405) 458-2276(DSN) 866-2276Labor & Delivery(C) (DSN) PRIVATEFort Stewart, GAWinn U.S. Army Community HospitalHospital -24 hour number(C) (912) 370-6666(DSN) 454-6666Labor & Delivery(C) (912) 370-6785/6786 (DSN) 454-6785 PRIVATEFort Wainwright, AKBassett U.S. Army Community HospitalOB-GYN Clinic(C) (907) 353-5253(DSN) 317-5253Labor & Delivery(C) (DSN) PRIVATEMadigan Army Medical Center, Tacoma, WAMadigan Army Medical CenterOB-GYN Clinic(C) (253) 968-1315/1735(DSN) 782-1315Labor & Delivery(C) (DSN)  PRIVATEWalter Reed AMC, Washington, DCWalter Reed Army Medical CenterOB-GYN Clinic(C) (202) 782-6201(DSN) 662-6201Labor & Delivery(C) 301-319-5000(C) 301-319-5000(DSN) 319-5000 PRIVATEWest Point, NYKeller U.S. Army Community HospitalOB-GYN Clinic(C) (914) 938-2606/4741(DSN) 688-2606Labor & Delivery(C) (DSN)  PRIVATEWilliam Beaumont AMC, El Paso, TXWilliam Beaumont Army Medical CenterHospital -24 hour number(C) (915) 569-2754/2090(DSN) 979-2754Labor & Delivery(C) (915) 569-2455/1822 (DSN) 979-2455 PRIVATEHonolulu, HITripler Army Medical CenterHospital -24 hour number(C) (808) 433-6661(DSN) 313-6661Labor & Delivery(C) (808) 433-5337/4178 (DSN) 313-5337 PRIVATEHeidelberg MEDDACHeidelberg MEDDAcHospital (C) 011-49-622-117-2287(DSN)Labor & Delivery(C) (DSN) PRIVATELandstuhl, GermanyLandstuhl Regional Medical Center OB-GYN Clinic(C) 011-49-6371-86-8157(DSN) Labor & Delivery(C)(DSN) 486-8208/8432 PRIVATE67TH Combat Support Hopital67th CSH, Wuerzburg, GermanyHospital (C) 011-49-931-804-3818/3716(DSN)Labor & Delivery(C) (DSN) PRIVATE121 Army Hospital, KoreaU.S. Army HospitalHospital -24 hour number(C) 011-822-7917 5400 (DSN) 695-0441 (Pentagon Switch) 315-737-5400Labor & Delivery(C) (DSN) 
PRIVATEUnited States Navy PRIVATEBeaufort, South CarolinaNaval HospitalHospital -24 hour number(C) 803-228-5600(DSN) 335-5600Labor Deck(C) 803-228-5571(DSN) 335-5571PRIVATEBethesda, MarylandNational Naval Medical CenterHospital -24 hour number(C) 301-295-4611(DSN) 295-4611Labor Deck*(C) 301-319-5000(C) 301-319-5000(DSN) 319-5000PRIVATEBremerton, WashingtonNaval HospitalHospital -24 hour number(C) 360-475-4232(DSN) 494-4232Labor Deck*(C) 360-475-4227(DSN) 439-4227PRIVATECamp Lejeune, North CarolinaNaval HospitalHospital -24 hour number(C) 910-451-4300(DSN) 484-4300Labor Deck(C) 910-451-4280(DSN) 484-4280 PRIVATECamp Pendleton, CaliforniaNaval HospitalHospital -24 hour number(C) 760-725-1288(DSN) 365-1288Labor Deck(C) 760-725-1509(DSN) 365-1509PRIVATECherry PointNaval HospitalHospital -24 hour number(C) 919-466-0266(DSN) 582-0266Labor Deck(C) 919-466-0460/0459(DSN) 582-0460/0459PRIVATEJacksonville, FloridaNaval HospitalHospital -24 hour number(C) 904-777-7301(DSN) 942-7301Labor Deck*(C) 904-777-7704(DSN) 942-7704PRIVATEPensacola, FloridaNaval HospitalHospital -24 hour number(C) 904-505-6601(DSN) 534-6601Labor Deck*(C) 904-505-6298(DSN) 534-6782PRIVATEPortsmouth, VirginiaNaval Medical CenterHospital -24 hour number(C) 757-953-5009(DSN) 564-5009**Labor Deck*(C) 757-953-5284(DSN) 564-5284**PRIVATESan Diego, CaliforniaNaval Medical CenterHospital -24 hour number(C) 619-532-6400(DSN) 522-6400Labor Deck*(C) 619-532-8865(DSN) 522-8865PRIVATETwentynine Palms, CaliforniaNaval HospitalHospital -24 hour number(C) 760-830-2190(DSN) 957-2190Labor Deck*(C) 760-830-2533/2534/2535(DSN) 957-2533/2534/2535 OUTCONUS PRIVATEGuam, Mariana IslandsNaval HospitalHospital -24 hour number(C) 011-671-344-9340(DSN) (NS) 344-9340Labor Deck(C) 011-850-505-6782/6789(DSN) (NS) 534-6782/6789PRIVATEGuantanamo Bay, CubaNaval HospitalHospital -24 hour number (ER)(C) 011-539-97-2690(DSN) 464-2690Labor Deck(C) 011-539-97-2063(DSN) 464-2063PRIVATEKeflavic, IcelandNaval HospitalHospital -24 hour number(C) 011-354-25-3300/3310(DSN) (NS) 450-320124-hour OB watchPRIVATENaples, ItalyNaval HospitalHospital -24 hour number(C) 011-39-81-724-4872(DSN) (NS) 625-4872Labor Deck(C) 011-39-81-724-4368/4399(DSN) (NS) 625-4368/4399PRIVATEOkinawa, JapanNaval HospitalHospital -24 hour number(C) 011-81-611-743-7555(DSN) (NS)643-7555Labor Deck*(C) 011-81-611-743-7597(DSN) (NS) 643-7597PRIVATERoosevelt Roads, Puerto RicoNaval HospitalHospital -24 hour number (ER)(C) 787-865-5767/5997(DSN) (NS) 831-5767/5997ISPU(C) 787-865-5911/5912(DSN) (NS) 831-5948PRIVATERota, SpainNaval HospitalHospital -24 hour number(C) 011-3456-82-3305(DSN) (NS) 727-3305Labor Deck(C) 011-3456-82-3655(DSN) (NS) 727-3655PRIVATESigonella, SicilyNaval HospitalHospital - 24 hour number(C) 011-39-95-56-4842(DSN) (NS) 624-4842Labor Deck(C) 011-39-95-56-4765(DSN) (NS) 624-4765PRIVATEYokosuka, JapanNaval HospitalHospital -24 hour number(C) 011-81-311-734-7144(DSN) (NS) 243-7144Labor Deck(C) 011-81-311-734-5311(DSN) (NS) 234-5311/7315
PRIVATEUnited States Air Force
PRIVATEAndrews Air Force Base, MDAir Force HospitalHospital - 24 hour number(C) (240) 857-5911(DSN) Labor & Delivery(C) (240) 857-5379(DSN) 857-5379 PRIVATEEglin Air Force Base, FLAir Force HospitalEmergency Room(C) (850) 883-8227(DSN) Labor & Delivery(C) (850) 883-8361/2(DSN) 875-8361/2 PRIVATEElmendorf Air Force Bace, AKAir Force HospitalEmergency Room(C) (907) 580-5555(DSN) Labor & Delivery(C) (907) 580-4595(DSN) 580-4595 PRIVATEGrand Forks Air Force Base, NDAir Force HospitalEmergency Room(C) (701) 747-5518(DSN) Family Medicine Clinic(C) (701) 747-5577(DSN) 362-5577 PRIVATEKeesler Air Force Base, MSAir Force HospitalEmergency Room(C) (228) 377-0500(DSN) Labor & Delivery(C) (228) 377-6228(DSN) 597-6228 PRIVATELackland Air Force Base, TXAir Force HospitalHospital Information(C) (210) 292-7412(DSN) Labor & Delivery(C) 210-292-7410/1(DSN) 554-7410/1 PRIVATELuke Air Force Base, AZAir Force HospitalEmergency Room(C) (623) 856-7506(DSN) Labor & Delivery(C) (623) 856-7565(DSN) 896-7565 PRIVATEMt. Home Air Force Base, IDAir Force HospitalEmergency Room(C) (208) 828-7100(DSN) Labor & Delivery(C) (208) 828-7170(DSN) 728-7170 PRIVATENellis Air Force Base, NVAir Force HospitalEmergency Room(C) (702) 653-2343(DSN) Labor & Delivery(C) (702) 653-3500(DSN) 348-3500 PRIVATEOffutt Air Force Base, NEAir Force HospitalEmergency Room(C) (402) 294-7333(DSN) Labor & Delivery(C) (402) 294-7391/2(DSN) 271-7391/2 PRIVATETravis Air Force Base, CAAir Force HospitalEmergency Room(C) (707) 423-3826(DSN) Labor & Delivery(C) (707) 423-3619(DSN) 799-3619 PRIVATEWright-Patterson Air Force Base, OHAir Force HospitalEmergency Room(C) (937) 257-0770(DSN) Labor & Delivery(C) (937) 257-1410(DSN) 787-1410 PRIVATEAviano, ItalyAir Force HospitalHospital - 24 hour number(C) (DSN) Labor & Delivery(C) (DSN) 314-632-5866 PRIVATEBitburg Air Force Base, GermanyAir Force HospitalHospital - 24 hour number(C) (DSN) Labor & Delivery(C) (DSN) 314-453-3500 PRIVATELakenheath, EnglandAir Force HospitalHospital -24 hour number(C) (DSN) 314-226-8386Labor & Delivery(C) (DSN)  PRIVATEMisawa, JapanAir Force HospitalHospital -24 hour number(C) (DSN) 315-226-6767Labor & Delivery(C) (DSN)  PRIVATEYokota, JapanAir Force HospitalHospital - 24 hour number(C) 702-653-3500(DSN) 315-225-3634Labor & Delivery(C) (DSN)  Table of Contents Page  PAGE iii Introduction Page  PAGE 3 PRIVATEBureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington, D.C 20372-5300Operational Obstetrics & Gynecology - 2nd Edition The Health Care of Women in Military Settings CAPT Michael John Hughey, MC, USNR NAVMEDPUB 6200-2A January 1, 2000 Routine Gynecologic Exam Page  PAGE 10 PRIVATEBureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington, D.C 20372-5300Operational Obstetrics & Gynecology - 2nd Edition The Health Care of Women in Military Settings CAPT Michael John Hughey, MC, USNR NAVMEDPUB 6200-2A January 1, 2000 Pap Smears Page  PAGE 27 Birth Control Pills Page  PAGE 40 Other Contraceptive Methods Page  PAGE 56 PRIVATEBureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington, D.C 20372-5300Operational Obstetrics & Gynecology - 2nd Edition The Health Care of Women in Military Settings CAPT Michael John Hughey, MC, USNR NAVMEDPUB 6200-2A January 1, 2000 Bleeding Page  PAGE 57 PRIVATEBureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington, D.C 20372-5300Operational Obstetrics & Gynecology - 2nd Edition The Health Care of Women in Military Settings CAPT Michael John Hughey, MC, USNR NAVMEDPUB 6200-2A January 1, 2000 Vaginal Discharge and Itching Page  PAGE 71 PRIVATEBureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington, D.C 20372-5300Operational Obstetrics & Gynecology - 2nd Edition The Health Care of Women in Military Settings CAPT Michael John Hughey, MC, USNR NAVMEDPUB 6200-2A January 1, 2000 Human Papilloma Virus Page  PAGE 74 PRIVATEBureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington, D.C 20372-5300Operational Obstetrics & Gynecology - 2nd Edition The Health Care of Women in Military Settings CAPT Michael John Hughey, MC, USNR NAVMEDPUB 6200-2A January 1, 2000 The Vulva Page  PAGE 92 PRIVATEBureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington, D.C 20372-5300Operational Obstetrics & Gynecology - 2nd Edition The Health Care of Women in Military Settings CAPT Michael John Hughey, MC, USNR NAVMEDPUB 6200-2A January 1, 2000 Problems with Menstruation Page  PAGE 97 PRIVATEBureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington, D.C 20372-5300Operational Obstetrics & Gynecology - 2nd Edition The Health Care of Women in Military Settings CAPT Michael John Hughey, MC, USNR NAVMEDPUB 6200-2A January 1, 2000 Abdominal and Pelvic Pain Page  PAGE 109 PRIVATEBureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington, D.C 20372-5300Operational Obstetrics & Gynecology - 2nd Edition The Health Care of Women in Military Settings CAPT Michael John Hughey, MC, USNR NAVMEDPUB 6200-2A January 1, 2000 Problems with Urination Page  PAGE 115 Breast Problems Page  PAGE 125 PRIVATEBureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington, D.C 20372-5300Operational Obstetrics & Gynecology - 2nd Edition The Health Care of Women in Military Settings CAPT Michael John Hughey, MC, USNR NAVMEDPUB 6200-2A January 1, 2000 Menopause Page  PAGE 131 PRIVATEBureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington, D.C 20372-5300Operational Obstetrics & Gynecology - 2nd Edition The Health Care of Women in Military Settings CAPT Michael John Hughey, MC, USNR NAVMEDPUB 6200-2A January 1, 2000 Sexual Assault Page  PAGE 141 PRIVATEBureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington, D.C 20372-5300Operational Obstetrics & Gynecology - 2nd Edition The Health Care of Women in Military Settings CAPT Michael John Hughey, MC, USNR NAVMEDPUB 6200-2A January 1, 2000 Normal Pregnancy Page  PAGE 155 PRIVATEBureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington, D.C 20372-5300Operational Obstetrics & Gynecology - 2nd Edition The Health Care of Women in Military Settings CAPT Michael John Hughey, MC, USNR NAVMEDPUB 6200-2A January 1, 2000 Abnormal Pregnancy Page  PAGE 169 PRIVATEBureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington, D.C 20372-5300Operational Obstetrics & Gynecology - 2nd Edition The Health Care of Women in Military Settings CAPT Michael John Hughey, MC, USNR NAVMEDPUB 6200-2A January 1, 2000 Normal Labor and Delivery Page  PAGE 187 PRIVATEBureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington, D.C 20372-5300Operational Obstetrics & Gynecology - 2nd Edition The Health Care of Women in Military Settings CAPT Michael John Hughey, MC, USNR NAVMEDPUB 6200-2A January 1, 2000 Labor and Delivery Problems Page  PAGE 200 PRIVATEBureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington, D.C 20372-5300Operational Obstetrics & Gynecology - 2nd Edition The Health Care of Women in Military Settings CAPT Michael John Hughey, MC, USNR NAVMEDPUB 6200-2A January 1, 2000 Care of the Newborn Page  PAGE 206 PRIVATEBureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington, D.C 20372-5300Operational Obstetrics & Gynecology - 2nd Edition The Health Care of Women in Military Settings CAPT Michael John Hughey, MC, USNR NAVMEDPUB 6200-2A January 1, 2000 Medical Support of Women in Field Environments Page  PAGE 220 PRIVATEBureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington, D.C 20372-5300Operational Obstetrics & Gynecology - 2nd Edition The Health Care of Women in Military Settings CAPT Michael John Hughey, MC, USNR NAVMEDPUB 6200-2A January 1, 2000 The Prisoner of War Experience Page  PAGE 223 Page  PAGE 221 OPNAVINST 6000.1A  PAGE 21 CAPT Michael John Hughey, MC, USNR Special Projects Officer for the Assistant Chief, Operational Medicine and Fleet Support Bureau of Medicine and Surgery Department of the Navy 2300 E Street NW Washington DC 20372-5300                                                    PRIVATE PRIVATE EMBED Word.Picture.8     (Y[efz{} y !7 (z(7 =K.#A#$$''p))*+]-|-Y/i/j/q/H0I0J0X0s22QAgAjB}BCCû CJOJQJOJQJhnH0J5<CJOJQJ 0J5<0JCJ$5CJ5CJCJ< jU B*CJ$H*B*CJ$CJ8 jUmHG()WXdeghi{~  ! !  ! ! $$$()WXdeghi{~'9KYm½|wrmh&4FXf  ''9KYm ,8CLT`n v ! !  ,8CLT`n 2G^zĿ~ytoje`[!8Mbv+3<GSaku}! 2G^z0=Oey  ! !  ! ! v ! ! 0=Oey  " + 6 C J ^ k ~   * 9 I W Ŀ~ytoje`[6FUe{!5<IT]hp0BOp!  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