ࡱ> ` bIbjbjss .Aa22222220t @@@8@4@KAAAAAAAAKKKKKKK$dMhO'K2AAAAA'K22AA 5 x ULN), treatment should be stopped. If muscular symptoms are severe and cause daily discomfort, even if CK levels are < 5 x ULN, treatment discontinuation may be considered. If myopathy is suspected for any other reason, treatment should be discontinued. eMC PIL - Zocor Tell your doctor quickly if you experience unexplained muscle pain, tenderness or weakness. This is because on rare occasions, there is a risk of muscle problems which may be serious, including muscle breakdown which can result in kidney damage. The doctor may perform a blood test to check the condition of your muscles before and after starting treatment. Things to note regarding muscle effects The risk of muscle breakdown is greater at higher doses of Zocor. The risk of muscle breakdown is greater in certain patients. Tell your doctor if any of the following applies to you: kidney problems thyroid problems you are more than 70 years old you have ever had muscle problems during treatment with cholesterol lowering medicines called "statins" (such as simvastatin, atorvastatin, pravastatin) or fibrates (such as gemfibrozil, bezafibrate). you or close family members have a hereditary muscle disorder. The risk of muscle problems can be greater if Zocor is taken with certain medicines NetDoctor: This medicine may occasionally have side effects on the muscles. For this reason you should inform your doctor immediately if you experience any unexplained muscular symptoms such as pain, tenderness, cramps or weakness while taking this medicine. Your doctor may need to check for side effects on the muscles by taking a blood test to measure the level of a compound called creatine kinase (CK) in your blood. If this is the case, the test should not be done following strenuous exercise. What advice would you give? Or would you refer? Statins may have very rare side effects on muscles. Advise that the husband see the GP immediately. The GP may advise that you stop this medication and may wish to do some blood test.      Role Preparation for Nurse Advisors: Handling Medicines Calls November 2007 v1.0   %&7fga s t  4 > ? 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