Advances in Systemic Cancer Therapy Alex A. Adjei
Advances in Systemic Cancer Therapy
Alex A. Adjei
ESMO Summit Africa
February 13, 2017 Cape Town, RSA
?2016 MFMER | slide-1
No conflicts of interest
?2016 MFMER | slide-2
Cancer Cells Adapt to Stress
?2016 MFMER | slide-3
Strategies for Targeting Hallmarks of Cancer
?2016 MFMER | slide-4
Novel Therapeutics
? Targets - multiple
? Methods of Inhibiting Targets ? limited
? Chemical therapy ? Small molecule inhibitors ? Monoclonal Antibodies ? Chimeric Antibodies ? Antibody Drug Conjugates ? Vaccines ? Adoptive T cell transfer ? Chimeric Antigen Receptor T-cells ? RNAi ? Gene Therapy ? Viral Therapies ? Clustered regularly interspaced short palindromic
repeats (CRISPR)
?2016 MFMER | slide-5
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