Statistical Modeling to Quantitate the Central Dogma
[Pages:19]Statistical Modeling to Quantitate the Central Dogma
Jingyi Jessica Li Department of Statistics University of California, Los Angeles May 21, 2018
What is Statistics?
16th-17th Century: Probability Theory (Mathematical Foundations of Statistics)
Jerome Cardan 1501-1576
Blaise Pascal 1623-1662
Pierre de Fermat 1607-1665
From Wikipedia 2
What is Statistics?
19th-20th Century: Emergence and Development of Statistics
Francis Galton 1822-1911
Karl Pearson 1857-1936
Ronald Fisher 1890-1962
From Wikipedia 3
What is Statistics?
21st Century: Computer Age of Statistics
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The Junction of Statistics and Biology
My Research Overview
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The Junction of Statistics and Biology
Our Team
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"The best thing about being a statistician is that you get to play in everyone's backyard." ? Dr. John W. Tukey
7
The Central Dogma
One of the Most Fundamental Principles of Modern Biological Sciences
[DNA]
transcription
[mRNA]
mRNA degradation
translation
protein degradation
[protein]
8
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