Feline Products - the meowing vet

Get Smart with Our

Chart: A Comparison

of Flea, Tick, and

Heartworm Products



Feline Products

Product &

Preventive vs.

Manufacturer Kills Only,

Mode &

Frequency of

Administration

Preventive

Activyl?

Topical

Spot-On for

Monthly

cats and

kittens

Merck

Advantage?II for cats

Bayer

Advantage

Multi? for

cats

May 5, 2017 ? 2016 The Meowing Vet.

All rights reserved.

Active

Ingredient(s)

(alphabetical

order)

Heartworm?

Fleas?

(adult,

larva,

pupa,

egg?)

Yes ¨C

adult fleas

and larva

Ticks?

Intestinal

Worms?

Other

Parasites?

Additional

Features &

Comments

Indoxacarb

No

No

No

No

Starts killing

fleas in 8

hours

Preventive

Topical

Monthly

Imidacloprid

No

Yes ¨C

all life

stages

No

No

Lice

Kills fleas in

12 hours,

they don¡¯t

have to bite;

may be toxic

to bees

Preventive

Topical

Monthly

Imidacloprid

Yes

Yes

No

Yes Roundworm

Hookworm

Ear mites

Also FDAapproved to

prevent fleas

and

heartworms

in ferrets

Pyriproxyfen

Moxidectin

Bayer

? The Meowing Vet ¨C Get Smart with Our Chart: A Comparison of Flea, Tick, and Heartworm Products ¨C ¨C CAT ¨C page 1

Product &

Preventive vs.

Manufacturer Kills Only,

Mode &

Frequency of

Administration

Preventive

Assurity?

Topical

for cats

Monthly

Elanco

Bravecto?

Topical

Solution

Merck

Capstar?

(Novartis)

Elanco

Preventive

Topical

3 months*

Active

Ingredient(s)

(alphabetical

order)

Heartworm?

Fleas?

(adult,

larva,

pupa,

egg?)

Yes ¨C

adult fleas

Ticks?

Intestinal

Worms?

Other

Parasites?

Spinetoram

No

No

No

No

Fluralaner

No

Yes

Yes* ¨C

No

Dermacentor

Ixodes

Rhipicephalus

Amblyomma*

May be

used offlabel to

treat

demodectic

mange

mites

Nitenpyram

No

Yes

No

No

*(only effective

for 2 months

against

Amblyomma

ticks, which can

transmit

Cytauxzoonosis)

Kills only

Oral

No

Additional

Features &

Comments

Kills 98100% of

fleas/ticks in

12 hours;

does not

repel insects;

may cause

vomiting;

safe for

pregnant and

nursing cats;

not for

younger

kittens

Starts

working in

30 minutes,

kills fleas in

2 hours; cats

may scratch

more

temporarily

after use as

fleas bite

more when

dying off

? The Meowing Vet ¨C Get Smart with Our Chart: A Comparison of Flea, Tick, and Heartworm Products ¨C ¨C CAT ¨C page 2

Product &

Preventive vs.

Manufacturer Kills Only,

Mode &

Frequency of

Administration

Preventive

Catego? for

Topical

cats

Monthly

Active

Ingredient(s)

(alphabetical

order)

Heartworm?

Fleas?

(adult,

larva,

pupa,

egg?)

Yes ¨C

all life

stages

Ticks?

Intestinal

Worms?

Other

Parasites?

Additional

Features &

Comments

Dinotefuran

No

Yes

No

Chewing

lice

Kills fleas in

6 hours, they

don¡¯t have to

bite; small

volume dose;

toxic to

rabbits

No

Yes

No

No

No

Preventive

Spinosad

Oral (with food)

Monthly

No

Yes

No

No

No

Preventive

Topical

Monthly

No

Yes ¨C

adult fleas

only

Yes

No

Chewing

lice

Kills fleas in

12 hours,

starts

working in

30 minutes;

small

volume dose

Starts killing

fleas in 30

minutes;

poor taste,

may cause

vomiting; do

not use on

pregnant or

nursing cats

Toxic to

rabbits

Fipronil

Pyriproxyfen

Ceva

Cheristin?

for cats

Preventive

Topical

Monthly

Spinetoram

Elanco

Comfortis?

Elanco

EasySpot?

for cats

Fipronil

Elanco

? The Meowing Vet ¨C Get Smart with Our Chart: A Comparison of Flea, Tick, and Heartworm Products ¨C ¨C CAT ¨C page 3

Product &

Preventive vs.

Manufacturer Kills Only,

Mode &

Frequency of

Administration

Preventive

EFFIPRO?

Topical

Topical

Monthly

Solution for

cats

Virbac

EFFIPRO

Plus?

Topical

Solution for

cats

Preventive

Topical

Monthly

Active

Ingredient(s)

(alphabetical

order)

Heartworm?

Fipronil

No

Fleas?

(adult,

larva,

pupa,

egg?)

Yes ¨C

adult fleas

only

Ticks?

Intestinal

Worms?

Other

Parasites?

Additional

Features &

Comments

Yes

No

Chewing

lice

Toxic to

rabbits

Mosquitoes

Firponil

Pyriproxyfen

No

Yes ¨C

all life

stages

Yes

No

Chewing

lice

Toxic to

rabbits

Mosquitoes

Virbac

A note on Frontline? topical products: Overall, these products are very safe for cats when used appropriately. However, with decades of use,

studies have shown decreased efficacy in some formulations. Kills ticks slowly (within 24-48 hours) compared to other products, perhaps

allowing various tick-borne infections to occur. Kills fleas in 8-24 hours.

Prevents flea

Preventive

Fipronil

No

Yes ¨C all

Yes

No

Chewing

Frontline?

re-infestation;

life stages

lice

Gold for cats Topical

toxic to

Monthly

Pyriproxyfen

rabbits

(S)-methoprene

Merial

? The Meowing Vet ¨C Get Smart with Our Chart: A Comparison of Flea, Tick, and Heartworm Products ¨C ¨C CAT ¨C page 4

Product &

Preventive vs.

Manufacturer Kills Only,

Mode &

Frequency of

Administration

Kills only

Frontline?

HomeGard

Household

spray

(do not apply

on your pet)

Active

Ingredient(s)

(alphabetical

order)

Heartworm?

Permethrin

No

Fleas?

(adult,

larva,

pupa,

egg?)

Yes ¨C

Ticks?

Intestinal

Worms?

Other

Parasites?

Additional

Features &

Comments

No

No

No

Use other

flea product

on pet at

least 3

months;

during use,

animals

should not

be in the

room,

humans

should leave

the room for

30 minutes

(until dried);

toxic to cats

when aerosol

or wet (cats

should avoid

contact until

product is

dried)

Toxic to

rabbits

kills adult

fleas on

contact and

disrupts the

development

of eggs and

larva

(S)-methoprene

Merial

Frontline?

Plus for cats

Merial

Frontline?

Spot On Cat

Preventive

Topical

Monthly

Fipronil

Preventive

Topical

Monthly

Fipronil

No

Yes ¨C

all life

stages

Yes

No

Chewing

lice

No

Yes ¨C

adult fleas

only

Yes

No

Chewing

lice

(S)-methoprene

Toxic to

rabbits; can

use on

pregnant or

nursing cats

Merial

? The Meowing Vet ¨C Get Smart with Our Chart: A Comparison of Flea, Tick, and Heartworm Products ¨C ¨C CAT ¨C page 5

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