CV - UT Southwestern Medical Center



Venkatesh Aiyagari, M.B.B.S., D.M., F.A.H.A.

PRESENT POSITION

Sept 2012-date Professor, Neurological Surgery and Neurology and Neurotherapeutics

Director, Division of Neurocritical Care

UT Southwestern Medical Center

Dallas, TX

EDUCATION AND TRAINING

Graduate

1980-1986 M.B.B.S.: Calcutta Medical College, Calcutta, West Bengal, India

Postgraduate

1987-1992 D.M. (Neurology): National Institute of Mental Health and Neurosciences, Bangalore, India

1994-1995 Intern: Department of Internal Medicine. Brooklyn Hospital Center, Brooklyn, NY.

1995-1997 Resident: Department of Neurology. New York University Medical Center, New York, NY.

1997-1998 Chief Resident: Department of Neurology. New York University Medical Center, New York, NY.

1998-2000 Fellow and Clinical Instructor: Neurology/Neurosurgery Intensive Care, Department of Neurology. Washington University School of Medicine, St. Louis, MO.

PREVIOUS EXPERIENCE

1992-1994 In-House Consultant: Department of Neurology, Manipal Hospital, Bangalore, India

2000-2005 Assistant Professor of Neurology and Neurosurgery

Washington University School of Medicine

St. Louis, Missouri

2005-2012 Associate Professor in Neurology (with tenure) and Co-director of Neurocritical Care

Department of Neurology and Rehabilitation

University of Illinois,

Chicago, Illinois

2012. Attending Physician

Resurrection Medical Center

Chicago, Illinois

BOARD CERTIFICATION AND MEDICAL LICENSURE

1993 Educational Commission for Foreign Medical Graduates

1999 Diplomate of the American Board of Psychiatry and Neurology

1998 Physician and Surgeon, Missouri, License # MD 114624 (inactive)

2005 Physician, Illinois, License # 36112951

2007 Certification in Neurocritical Care by the United Council for Neurologic Subspecialities

2008 Certification in Vascular Neurology by the American Board of Psychiatry and Neurology

2012 Physician, Texas, License# P4136

HONORS AND AWARDS

1978 National Scholar, India

1980 Senior Prosector Prize in Anatomy, Medical College, Calcutta

1980 Goodeve Silver Medal in Anatomy, Medical College, Calcutta

1981 Raye Testimonial Prize in Anatomy, Medical College, Calcutta

1981 Gold Medal In Anatomy, Medical College, Calcutta

1982 Senior Class Assistantship in Medicine, Medical College, Calcutta

1982 Senior Class Assistantship in Pathology, Medical College, Calcutta

1983 Girish Chandra Ghosh Prize (Silver Casket) in Pathology, Medical College, Calcutta

1984 Sir Frank Conner Memorial Prize in Surgery, Medical College, Calcutta

1985 Best outgoing student, Medical College, Calcutta

1985 Dr. Sailen Sen Memorial Medal in Medicine, Medical College, Calcutta

1986 Dr. B.C.Roy Memorial Medal And Prize awarded by the Prime Minister of India, Shree Rajiv Gandhi

1992 Silver Jubilee Award as best outgoing student of 1992 in D.M. (Neurology), National Institute of Mental Health and Neurosciences, Bangalore

2006 John S. Garvin MD Teacher of the Year Award, Department of Neurology, University of Illinois at Chicago

2010 John S. Garvin MD Teacher of the Year Award, Department of Neurology, University of Illinois at Chicago

2010 Fellow of the American Heart Association (Stroke Council)

2012 John S. Garvin MD Teacher of the Year Award, Department of Neurology, University of Illinois at Chicago

2012 Lifesaving Partners Award, Gift of Hope (Organ & Tissue Donor Network)

2017 Golden Pager Award, UT Southwestern Medical Center

PROFESSIONAL SOCIETIES AND ORGANIZATIONS

1995-date American Academy of Neurology

2000-2009

and

2012-date Society of Critical Care Medicine

2000-date American Academy of Neurology, Section on Critical Care and Emergency Neurology

2002-date American Heart Association (Stroke Council)

2002-date Neurocritical Care Society

2006-2009 Program Committee Member, International Stroke Conference – Category Chair: Intracerebral Hemorrhage

2007-2012 Member of nominating committee, Neurocritical care Society

HOSPITAL AND DEPARTMENTAL COMMITTES

2005-date Co-Director, Neurointensive Care, UIC Department of Neurology

2006-date Member, UIC Hospital Organ donation committee

2008-date Chairman, UIC Department of Neurology Website Committee

2008-2009

and

2010-2012 Chairman, UIC Department of Neurology Grand Rounds Committee

2013-date Member, Pharmacy & Therapeutics Committee: UT Southwestern Medical Canter

2013-date Member, Performance Improvement Committee, UT Southwestern Medical Center

2014-date Member, Critical Care Committee, UT Southwestern Medical Center

2018- Chairman, Critical Care Committee, UT Southwestern Medical Center

INVITED LECTURESHIPS AT INTERNATIONAL SYMPOSIA

2000 Medical Management of subarachnoid hemorrhage: Medical treatment of vasospasm, Society of Critical Care Medicine, San Francisco

2002 Postgraduate review course: Update on Neurological Critical Care – Acute Spinal Cord Compression, Society of Critical Care Medicine, San Diego

2003 Blood pressure in intracerebral hemorrhage, American Academy of Neurology, Honolulu

2004 Blood pressure in intracerebral hemorrhage, American Academy of Neurology, San Francisco

2005 3rd National workshop on Neurocritical Care, Hyderabad, India

2005 Blood pressure in intracerebral hemorrhage, American Academy of Neurology, San Francisco

2006 Brian Hypertension relationships: Acute intervention, American Society of Hypertension, New York

2007 Critical Care of Brain Hemorrhage: management of the Anticoagulated patient, American Academy of Neurology, Boston

2008 “The AHA Guidelines for Management of Blood Pressure in Patients with Acute Ischemic and Hemorrhagic Stroke” and “Should Blood Pressure Be Lowered or Elevated in Acute Ischemic or Hemorrhagic Stroke?” American Society of Hypertension, New Orleans

2008 “Acute management of intracerebral hemorrhage”, “Osmotic therapy and regulation of brain volume” and “Management of subarachnoid hemorrhage: The role of the intensivist”, Vivekananda Institute of Medical Sciences, Neuroupdate 2008, Kolkata, India

2011 Hypertension in the Neurological/Neurosurgical Patient, American Society of Nephrology, Philadelphia

2015 Intracerebral hemorrhage: Contemporary management and updates, American Academy of Neurology, Washington DC

2015 Neurocritical care Pearls, Indian Academy of Neurology, Agra, India

2105 Challenging Case, Indian Academy of Neurology, Agra, India

2016 Cerebrovascular Disease II: Hemorrhagic Stroke, American Academy of Neurology, Vancouver, Canada

2017 Cerebrovascular disease II: Hemorrhagic Stroke. Evidence-based diagnosis and management of intraparenchymal hemorrhage, American Academy of Neurology, Boston, USA

MAJOR INVITED LECTURESHIPS

2000 Critical Illness Neuropathy, Pulmonary and Critical Care Grand Rounds, St. Louis University School of Medicine

2003 Management of blood pressure after acute stroke, Neurology Grand Rounds, New York University, New York

2005 Management of blood pressure after acute ischemic stroke. Dr. M. S. Sanjeevi Rao Oration in Neurology, Nizam’s Institute of Medical Sciences, Hyderabad, India

2006 Osmotic therapy and regulation of brain volume, Neurology Grand Rounds, University of Illinois at Chicago

2007 Management of anticoagulant-associated cerebral hemorrhage, Neurology Grand Rounds, University of Illinois at Chicago

2007 Morbidity and mortality conference: An introduction, Neurology Grand Rounds, University of Illinois at Chicago

2007 Regulation and manipulation of brain volume, Nephrology Grand Rounds, University of Illinois at Chicago

2008 Acute management of Intracerebral Hemorrhage, Internal Medicine Grand Rounds, St. Mercy’s Hospital, Chicago, IL

2008 Intensive care Unit management of acute ischemic stroke, Neurovascular Symposium, Chicago IL

2009 Neurologic criteria for determination of death, Ethics Grand Rounds, University of Illinois at Chicago

2010 Neurological Emergencies, Medicine Grand Rounds, Thorek Hospital, Chicago

2010 Defining irreversible end of life (brain death): Medical and legal issues, University of Illinois, Chicago

2010 Radiation exposure from computed tomographic scans, Neurology Grand Rounds, University of Illinois at Chicago

2014 A history of vasospasm management, Neurosurgery Grand Rounds – Visiting Professor Series, University of Texas Southwestern Medical Center, Dallas, Texas

2015 Status epilepticus: Recent Advances, Santokba Durlabhji Hospital, Jaipur, India

2017 Management of Acute Neurological Injury – A Neuro-Intensivist Perspective. Cardiovascular & Neurovascular Symposium. Texas Health Presbyterian Hospital, Dallas, Texas

2017 Subarachnoid hemorrhage management– Parkland Stroke symposium, Dallas, Texas

2017 Management of cerebral edema and raised intracranial pressure. North Central Texas Trauma Regional Advisory Council Cardiac and Stroke Symposium, Grand Prairie, Texas

2017 Hypertension and Stroke. “Critical Decisions in Stroke”- Stroke Symposium. UT Southwestern Medical Center, Dallas, Texas.

EXPERIENCE TRAINING FELLOWS

1999-2001 Edgar Garcia-Morales, MD

2000-2001 Dean Roller, MD

2002-2003 Fransisco Gondim, MD

2002-2003 John Zurasky, MD

2003-2004 Wiley Hall, MD

2004-2005 Ykaterina Axelrod, MD

2005-2007 Kurian Thomas, MD

2007-2008 Fernando Testai, MD PhD

2008-2009 Aamir Badruddin, MD

2009-2010 Rebecca Griesewicz, DO

2010-2011 Noam Epstein, MD

2011-2012 Hermina Muqtadar, MD

2012-2013 Stephen Figueroa, MD

2012-2013 Bappaditya Ray, MD

2013-2014 Ashraf Ahmed, MD

2013-2015 Iswara R Sankara, MD

2014-2016 Junaid Kalia, MD

2014-2016 Naregnia Pierre-Louis, MD

2014-2016 Shraddha Mainali, MD

2015-2017 Claudia Perez, MD

2015-2017 Zakraus Mahdavi, MD

2016-2017 Bethany Lussier, MD

2016-2018 Adam Willis, MD

2016-2018 Mohammed Osman, MD

2017- Jia Romito, MD

2017- Lalith Premachandra, MD

2017- Ahmed Salem, MD

AD-HOC REVIEWER

Neurology

Journal of Critical Illness

Neurocritical Care

Annals of Neurology

Archives of Neurology

Stroke

Critical Care Medicine

Journal of Neurotrauma

Critical Care

JAMA Neurology

Journal of Critical Care

BMC Neurology

Journal of Cerebrovascular diseases and Stroke

ORAL PRESENTATIONS AT INTERNATIONAL CONFERENCES

2000 Safety of hemodynamic augmentation in patients treated with Guglielmi detachable coils following acute aneurysmal subarachnoid hemorrhage. American Academy of Neurology, San Diego, California.

2001 Hypernatremia in the Neurology-Neurosurgery Intensive Care Unit. American Academy of Neurology, Philadelphia.

2004 Blood pressure monitoring after IV tPA for stroke: Who needs it? American Academy of Neurology, San Francisco.

2010 Radiation exposure from computed tomography in patients with subarachnoid hemorrhage. International Stroke Conference, San Antonio

POSTER PRESENTATIONS AT INTERNATIONAL CONFERENCES

2009 Predictors of increased intracranial pressure in patients with intracerebral hemorrhage. Neurocritical Care Society, New Orleans

BIBLIOGRAPHY

A) PEER REVIEWED PUBLICATIONS

Gupta SK, Satishchandra P, Venkatesh A, Subbakrishna DK. Prognosis of single unprovoked seizure. Journal of Association of Physicians of India 1993; 41:709-710

Suresh TG, Gupta SK, Venkatesh A, Satishchandra P. Chronic Ischemic monomelic neuropathy. Journal of Association of Physicians of India 1993; 41:683-684

1. Jonas S, Aiyagari V, Viera D, Waterman P. Neuroprotection against cerebral ischemia. A review of animal studies and correlation with human trial results. Annals of the New York Academy of Sciences 1999; 890:2-3.

2. Diringer MN, Yundt K, Videen T, Adams RE, Zazulia AR, Deibert E, Aiyagari V, Dacey RG, Grubb RL, Powers WJ. No reduction in cerebral metabolism as a result of early moderate hyperventilation following severe traumatic brain injury. Journal of Neurosurgery 2000; 92:7-13.

3. Deibert E, Aiyagari V, Diringer MN. Reversible left ventricular dysfunction associated with raised troponin I after subarachnoid hemorrhage does not preclude successful transplantation. Heart 2000; 84:205-207.

4. Aiyagari V, Cross DT, Deibert E, Dacey RG, Diringer MN. Safety of hemodynamic augmentation in patients treated with Guglielmi detachable coils following acute aneurysmal subarachnoid hemorrhage. Stroke 2001; 32:1994-1997.

5. Diringer MN, Edwards DF, Aiyagari V, Hollingsworth H. Factors associated with withdrawal of mechanical ventilation in a neurology/neurosurgery intensive care unit. Critical care Medicine. 2001; 29: 1792-1797.

6. Jonas S, Aiyagari V, Vieira D, Figueroa M. The failure of neuroprotective agents versus the success of thrombolysis in the treatment of ischemic stroke. The predictive value of animal models. Annals of the New York Academy of Sciences 2001; 939: 257-267

7. Powers WJ, Zazulia AR, Videen TO, Adams RE, Yundt KD, Aiyagari V, Grubb RL Jr., Diringer MN. Autoregulation of cerebral blood flow surrounding acute (6 to 22 hours) intracerebral hemorrhage. Neurology 2001; 57:18-24

8. Zazulia AR, Diringer MN, Videen TO, Adams RE, Yundt K, Aiyagari V, Grubb RL Jr., Powers WJ. Hypoperfusion without ischemia surrounding acute intracerebral hemorrhage. Journal of Cerebral Blood Flow and Metabolism. 2001; 21:804-10

9. Diringer MN, Videen T, Yundt K, Zazulia AR, Aiyagari V, Dacey RG, Grubb RL, Powers WJ. Regional cerebrovascular and metabolic effects of hyperventilation after severe traumatic brain injury. Journal of Neurosurgery. 2002; 96:103-8

10. Diringer MN, Zazulia AR, Aiyagari V, Dacey RG, Grubb RL, Powers WJ. Hyperventilation: Response. Neurosurgical forum. Journal of Neurosurgery. 2002; 96:158-159

11. Aiyagari V, Diringer MN. Management of large hemispheric strokes in the neurological intensive care unit. The Neurologist 2002; 8:152-162

12. Deibert E, Barzilai B, Braverman A, Edwards DF, Aiyagari V, Garcia-Morales E, Dacey R, Diringer M. The clinical significance of elevated troponin – I in patients with nontraumatic subarachnoid hemorrhage. Journal of Neurosurgery 2003; 98:741-746

13. Qu F, Aiyagari V, Cross DT, Dacey RG, Diringer MN. Untreated subarachnoid hemorrhage: Who, Why and When? Journal of Neurosurgery 2004; 100:244-249

14. Aiyagari V, Gujjar A, Zazulia AR, Diringer MN. Hourly blood pressure monitoring after intravenous tissue plasminogen activator for ischemic stroke: Does everyone need it? Stroke 2004; 10:2326-2330

15. Zurasky J, Aiyagari V, Zazulia A, Shackelford A, Diringer MN. Early mortality following spontaneous intracerebral hemorrhage. Neurology 2005; 64:725-727

16. Brody DL, Aiyagari V, Shackelford AM, Diringer MN. Use of recombinant Factor VIIa in patients with warfarin-associated intracranial hemorrhage. Neurocritical Care 2005; 2:263-267

17. Aiyagari V, Menendez J, Diringer MN. Treatment of severe coagulopathy after gunshot wound to the head using recombinant activated factor VII. Journal of Critical Care 2005; 20:176-180

18. Jost SC, Diringer MN, Zazulia AR, Videen TO, Aiyagari V, Grubb RL, Powers WJ. Normal saline bolus increases cerebral blood flow in regions with low baseline flow in patients with vasospasm following subarachnoid hemorrhage. Journal of Neurosurgery 2005; 103:25-30

19. Gondim FAA, Aiyagari V, Shackelford A, Diringer MN. Osmolality does not predict mannitol-induced renal insufficiency. Journal of Neurosurgery 2005; 103:444-447

20. Aiyagari V, Deibert E, Diringer MN. Hypernatremia in the neurological intensive care unit: How high is too high? Journal of Critical Care 2006; 21:163-172

21. Diringer MN, Aiyagari V, Zazulia AR, Videen TO, Powers WJ. Effect of hyperoxia on cerebral metabolic rate for oxygen measured using positron emission tomography in patients with acute severe head injury. Journal of Neurosurgery 2007; 106:526-529

22. Mayer SA, Brun NC, Begtrup K, Broderick J, Davis S, Diringer MN, Skolnick BE, Steiner T; FAST Trial Investigators. Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage. N Engl J Med. 2008; 358:2127-37

23. Majic T, Aiyagari V. Cerebrovascular Manifestations of Pheochromocytoma and the Implications of a Missed Diagnosis. Neurocrit Care. 2008; 9:378-381

24. Powers W J, Videen TO, Diringer MN, Aiyagari V, Zazulia A. Autoregulation after ischemic stroke. Journal of Hypertension 2009; 27:2218-2222

25. Whited K, Aiyagari V, Calderon-Arnulphi M, Cursio J, Pandey D, Hillman M, Ruland S. Standardized admission and discharge templates to improve documentation of The Joint Commission on Accreditation of HealthCare Organization performance markers. Journal of Neuroscience Nursing 2010; 42:225-228

26. Testai FD, Aiyagari V. Dabigatran and other oral antithrombotic agents for the prevention of stroke in patients with atrial fibrillation. Res Rep Clin Cardio 2011:2 71–81

27. Testai FD, Aiyagari V, Hillmann M, Amin-Hanjani S, Dawson G, Gorelick P. Proof of concept: endogenous antiangiogenic factors predict the occurrence of symptomatic vasospasm post subarachnoid hemorrhage. Neurocrit Care. 2011;15:416-420

28. Carbunar O, Aiyagari V. Teaching neuroimages: an unusual case of syncope. Neurology 2012;78:e83-84

29. Aiyagari V, Pandey DK, Testai FD, Grysiewicz RA, Tsiskaridze A, Sacks C, Ogun Y, Ogunrin OA, Uthman BM, Lindsay P, Gorelick PB. A prototype worldwide survey of diagnostic and treatment modalities for stroke. J Stroke Cerebrovasc Dis 2015;24:290-296 epub Nov 2014

30. Olson DM, Stutzman S, Saju C, Wilson M, Zhao W, Aiyagari V. Interrater Reliability of Pupillary Assessments. Neurocrit Care. 2016;24:251-7 epub 2015

31. Zhao W, Stutzman S, DaiWai O, Saju C, Wilson M, Aiyagari V. Inter-device reliability of the NPi-100 pupillometer. J Clin NeuroSci. 2016;33:79-82

32. Derdeyn CP, Zipfel GJ, Zazulia AR, Davis PH, Prabhakaran S, Ivan CS, Aiyagari V, Sagar JR, Hantler N, Shinawi L, Lee JJ, Jafri H, Grubb RL Jr, Miller JP, Dacey RG J. Baseline Hemodynamic Impairment and Future Stroke Risk in Adult Idiopathic Moyamoya Phenomenon: Results of a Prospective Natural History Study. Stroke. 2017;48:894-899

33. Olson DM, Stutzman SE, Atem F, Kincaide JD, Ho T, Carlisle BA, Aiyagari, V. Establishing Normative Data for Pupillometer Assessment in Neuroscience Intensive Care: The “END-PANIC” Registry. Journal of Neuroscience Nursing. 2017;49:251-254

34. Mahdavi ZK, Narayan R, Mainali S, Greenberg BM, Aiyagari V, McDonagh DL.A callosal catastrophe: Toxic encephalopathy associated with thermogenic weight loss supplement use. Neurocrit Care. 2017, Oct 18. Doi 10.1007/s12028-017-0473-9. [Epub ahead of print]

35. Aiyagari V, Rhines B. Unwrap the Brain With Rap. Journal of Neuroscience Nursing, 2018 Publish Ahead of Print. doi:10.1097/jnn.0000000000000332

B) INVITED PUBLICATIONS

1. A Venkatesh, Deibert E, Diringer MN. Hemodynamic Manipulation in the Neurological Intensive Care Unit. Neurology India 2001 49(Suppl. 1):S9-S18

2. Aiyagari V, Diringer MN. Take Notice Technology Cool Gard/Cool Line TM. Neurocritical Care 2004; 1:209-211

3. Aiyagari V, Diringer MN. Fever control and its impact on outcomes: What is the evidence? Journal of Neurological Sciences 2007; 261:39-46

4. Ruland S, Aiyagari V. Cerebral autoregulation and blood pressure lowering. Hypertension 2007; 49:977-8

5. Testai FD, Aiyagari V. Acute hemorrhagic stroke pathophysiology and medical interventions: blood pressure control, management of anticoagulant-associated brain hemorrhage and general management principles. Neurol Clin 2008; 26:963-985

6. Aiyagari V, Badruddin A. The management of hypertension in acute stroke. Expert Review of Cardiovascular Therapy 2009; 7:637-646

7. Aiyagari V, Testai F. Correction of coagulopathy in warfarin associated cerebral hemorrhage. Current Opinion in Critical Care 2009; 15:87-92

8. Aiyagari V. Correction of coagulopathy secondary to oral and parenteral anticoagulants. Continuum Lifelong Learning Neurol 2009;15:130-57

9. Aiyagari V, Gorelick PB. Management of blood pressure for acute stroke and recurrent stroke prevention. Stroke 2009; 40:2251-6

10. Pandey D, Aiyagari V. Prevention of second strokes through blood pressure lowering: update for 2011. Curr Cardiovasc Risk Rep 2011;5:299–306

11. Goerlick PB, Aiyagari V. The management of hypertension for acute stroke: What is the blood pressure goal? Curr Cardiol Rep 2013;15:366

12. Figueroa SA, Zhao W, Aiyagari V. Emergency and critical care management of acute ischaemic stroke. CNS Drugs 2015; 29:17-28

13. Aiyagari V, Diringer M. Cognition and Quality-of-Life Outcomes in the Targeted Temperature Management Trial for Cardiac Arrest. JAMA Neurol. 2015;72:628-30

14. Aiyagari V. The clinical management of acute intracerebral hemorrhage. Expert Rev Neurother. 2015;15:1421-32

15. Perez CA, Samudra N, Aiyagari V. Cognitive and Functional Consequence of Cardiac Arrest. Curr Neurol Neurosci Rep. 2016;16:70

C) TEXTBOOKS

Hypertension and Stroke: Pathophysiology and Treatment (Clinical Hypertension and Vascular Diseases). Editors: Venkatesh Aiyagari and Philip B Gorelick. Humana Press, 2011

Hypertension and Stroke: Pathophysiology and Management (Clinical Hypertension and Vascular Diseases). Second Edition. Editors: Venkatesh Aiyagari and Philip B Gorelick. Humana Press, 2016

D) BOOK CHAPTERS

1. Aiyagari V. Contibuting Editor for Neurologic Care. The Year Book of Critical Care Medicine. Editors-in-Chief: R. Phillip Dellinger, MD and Joseph E. Parrillo, MD. June 2004. Elsevier Science, Philadelphia PA.

2. Aiyagari V, Powers W, Diringer M. Cerebrovascular disease. Principles of Critical Care. Editors: Jesse B. Hall, Gregory A. Schmidt, Lawrence D. Wood. 3rd edition. July 2005. McGraw Hill Professional, New York NY.

3. Aiyagari V. Raised intracranial pressure – Pathophysiology and management principles. Neurology in Neurosurgical Practice. Editor: Ambar Chakravarty. 2005. Journal of Association of Neuroscientists of Eastern India, Kolkata India.

4. Diringer MN and Aiyagari V. Disturbances of fluid and electrolytes in critically ill neurological patients. Neurological Therapeutics: Principles and Practice. Editor-in-chief: Noseworthy J. 2nd edition, Abingdon, Oxon, UK, Informa Healthcare, New York, NY, Taylor & Francis, 2006.

5. Aiyagari V and Ruland S. Neurogenic Hypertension including following Stroke and Spinal Cord Injury. Comprehensive Clinical Nephrology. Editors: John Feehally, Jurgen Floege, Richard J. Johnson. 3rd Edition. Mosby, 2007.

6. Aiyagari V, Ruland S and Gorelick PB. Neurogenic Hypertension including following Stroke and Spinal Cord Injury. Comprehensive Clinical Nephrology. Editors: John Feehally, Jurgen Floege, Richard J. Johnson. 4th Edition. Elsevier, 2010

7. Bansal V, Aiyagari V, Ruland S. Disorders of Consciousness. Clinical Neurology 2nd ed. Editors: Philip B. Gorelick and Fernando D Testai. Manson Publishing, 2014

8. Aiyagari V. Acute blood pressure management after ischemic stroke. Editors: Venkatesh Aiyagari and Philip B. Gorelick. Humana Press, 2011

9. Aiyagari V, Gorelick PB. Recurrent Stroke Prevention II: Angiotensin Receptor Blockers (ARBs) – The LIFE, MOSES and PROFESS Trials. Editors: Venkatesh Aiyagari and Philip B. Gorelick. Humana Press, 2011

10. Aiyagari V. Acute blood pressure management after intracerebral hemorrhage. Hypertension and Stroke: Pathophysiology and management. 2nd edition. Editors: Venkatesh Aiyagari and Philip B. Gorelick. Humana Press, 2016

E) BOOK REVIEWS

1. Aiyagari V. Book review. Neurology of Breathing. Annals of Neurology 2004; 56:312-313

F) LETTERS TO THE EDITOR

1. Aiyagari V, Diringer MN. Response to discussion by Dr. Philip Hebert. Journal of Critical Care 2006; 21:115-116

2. Aiyagari V. Counteracting the effects of anticoagulants and antiplatelet agents during neurosurgical emergencies. Neurosurgery. 2006 Nov;59(5):E1152

G) ABSTRACTS

1. Rajan AB, Carniciu S, Aiyagari V, Weinreb HJ. Aortic atherosclerosis is an independent risk factor for stroke. Annals of Neurology 1997; 42:440

2. Deibert E, Aiyagari V, Braverman A, Barzalai B, Cryer P, Dacey R, Diringer MN. Troponin-I is a more sensitive marker than creatinine kinase-MB isoenzyme of left ventricular dysfunction in patients with acute subarachnoid hemorrhage. Critical Care Medicine 1999;S(27);A59

3. Aiyagari V, Cross DT, Deibert E, Diringer MN. Safety of hemodynamic augmentation in patients treated with Guglielmi detachable coils following acute aneurysmal subarachnoid hemorrhage. Neurology 2000;54(Suppl 3):A228

4. Deibert EM, Edwards DF, Hart J, Krupp J, Ball C, Kremen S, Aiyagari V, Diringer MN. Development of a bedside cognitive scale for acutely ill neurology/neurosurgery patients. Neurology 2000; 54(Suppl 3):A310

5. Diringer MN, Yundt K, Videen T, Adams RE, Zazulia AR, Deibert E, Aiyagari V, Dacey RG, Grubb RL, Powers WJ. Effect of hyperventilation on cerebral hemodynamics and oxygen metabolism following acute brain injury. Stroke 2000; 31:296

6. Zazulia AR, Diringer MN, Videen TO, Aiyagari V, Deibert EM, Powers WJ. Acute intracerebral hemorrhage does not produce peri-clot ischemia. Neurology 2000; 54(Suppl 3):A261

7. Zazulia AR, Videen TO, Diringer MN, Deibert EM, Aiyagari V, Powers WJ. Early increase in cerebral blood flow after intracerebral hemorrhage is not associated with clinical improvement. Stroke 2000; 31:333

8. Diringer MN, Zazulia AR, Videen TO, Grubb RL, Aiyagari V, Powers RJ. Hyperventilation of traumatic brain injury patients lowers cerebral blood flow below 20 ml/100g/min without impairing regional cerebral metabolism. Neurology 2001;56:A468

9. Aiyagari V, Diringer MN, Hypernatremia and Mortality in the Neurology/Neurosurgery Intensive Care Unit, Neurology 2001:56 A469.

10. Zazulia AR, Diringer MN, Videen TO, Adams RE, Yundt K, Aiyagari V, et al. Effects of acute ICH on hemispheric blood flow and metabolism. Stroke 2001;32:338

11. Zazulia AR, Diringer MN, Videen TO, Adams RE, Yundt K, Aiyagari V, Grubb RL, PowersWJ, Peri-Clot CMRO2 as a Measure of Ongoing Tissue Injury after Acute Intracerebral Hemorrhage, Neurology 2001:56 A434.

12. Diringer MN, Zazulia AR, Aiyagari V, Videen TO, Deibert E, Powers WJ. Large fluid bolus does not improve cerebral blood flow in patients with clinical and angiographic vasospasm following subarachnoid hemorrhage. Neurology 2002;58(7):A94

13. Diringer MN, Zazulia AR, Aiyagari V, Videen TO, Deibert E, Dacey RJ, et al. Large fluid bolus does not improve cerebral blood flow in patients with clinical and angiographic vasospasm following subarachnoid hemorrhage. Stroke 2002;33(1):379

14. Diringer MN, Aiyagari V, Shackleford AM, Brody DL, Use of Recombinant Factor VIIa in Patients with Warfarin-Associated Intracranial Hemorrhage. Blood 2003: 102(11).

15. Aiyagari V, Gujjar AR, Zazulia A, Diringer MN. Blood pressure monitoring after IV-tPA for acute ischemic stroke: who needs it? Neurology 2004;62(Suppl 5) A449

16. Gondim FAA, Aiyagari V, Shackleford A, Diringer M. Predictors of mannitol-induced renal insufficiency in a neurological/neurosurgical intensive care unit. Neurology 2004;62(Suppl 5) A367

17. Zurasky J, Aiyagari V, Hall W, Shackleford A, Zazulia A, Diringer MN. Cause of death in intracerebral hemorrhage. Neurology 2004;62(Suppl 5) A447

18. Diringer M, Aiyagari V, Videen T, Zazulia A, Powers W. Hyperoxia Does Not Increase Cerebral Metabolic Rate for Oxygen in Traumatic Brain Injury. Neurology 2006

19. Pandey DK, Ruland S, Aiyagari V, Cursio J, Gorelick PB. Prior anticoagulation therapy is associated with higher risk of death in acute intracerebral hemorrhage: IL capture stroke. Circulation 2008; 117 (21): 49.

20. Stone JL, Roitberg BZ, Calderone-Arnulphi M, Herrera S, Munson T, Emechebe-Kennedy O, Aiyagari V, Ruland S. A non-invasive intracranial pressure monitor utilizing modified brainstem auditory responses. J Neurosurg 2009;110:A1085

21. Pandey D, Aiyagari V. Does race influence disability and hospital disposition after cerebral hemorrhage? Results form a community-wide registry. Presented at Quality of Care and Outcomes Research in Cardiovascular Disease and Stroke. May 19-21, 2010. Washington DC

22. McConeghy K, Kim K, Tesoro E, Mucksavage J, Khaja A, Aiyagari V, Ruland S. Effect of home beta-blocker use in patients presenting with subarachnoid hemorrhage. Presented at the Annual meeting of the American College of Clinical Pharmacy, Pittsburgh, PA October 16-19, 2011

23. Derdyn C, Sagar J, Lee J, Aiyagari V, Davis P, Ivan C, Prabhakaran S, Shinawi L, Hantler N. The impact of hemodynamic factors on stroke risk in Moyamoya phenomenon: A prospective natural history study. Presented at the International Stroke Conference, New Orleans LA, Feb 1-3, 2012

24. Sagar J, Lee J, Shimony J, Zazulia A, Davis P, Aiyagari V, Ivan C, Prabhakaran S, Zipfel G, Derdeyn C. High resolution MR imaging of intracranial arterial vessel walls in Moyamoya disease. Presented at the International Stroke Conference, New Orleans LA, Feb 1-3, 2012

25. Testai FD, Aiyagari V, Hillmann M, Amin-Hanjani S, Max J, Dawson G, Gorelick PB. Relative deficiency of vascular endothelial growth factor (VGEF) in subarachnoid hemorrhage. Presented at the International Stroke Conference, New Orleans LA, Feb 1-3, 2012

26. Figueroa SA, Olson DM, Aiyagari V, Hall C, Correlation of Brain Tissue Oxygenation and Intracranial Pressure Monitoring in Severe Traumatic Brain Injury. Neurocritical care society 11th annual meeting. Neurocritical care. 2013;19:1-331

27. Sankara I R, Aiyagari V. An unusual case of hypotension in a patient with aneurysmal subarachoid hemorrhage. Presented at the Neurocritical Care Society Annual Meeting, Seattle, Sept 11-14, 2014

28. Stutzman SE, Olson DM, Saju C, Wilson M, Aiyagari V. Interrater reliability of pupillary assessments among physicians and nurses. Presented at the Neurocritical Care Society Annual Meeting, Seattle, Sept 11-14, 2014

29. Mahdavi Z, Figueroa S, Olson D, Hall C, Aiyagari V. Association patterns of intraventricular and intraparenchymal simultaneous ICP measurements. Presented at the American Academy of Neurology Annual Meeting, Washington DC, April 18-24, 2015

30. Mainali S, Thomas J, Aiyagari V, Figueroa SA, Welch B. Natural History and Etiology of Subarachnoid Hemorrhage Associated with Sexual Activity: Single Center Observational Study and Review of the Literature. Neurocritical care society 13th annual meeting. Neurocritical care. 2015

31. Zhao W, Olson D, Stutzman S, Saju C, Wilson M, Aiyagari V. Inter-Rater Reliability of Automated Pupillometer Assessments. Presented at the American Academy of Neurology Annual Meeting, Washington DC, April 18-24, 2015

32. Liu MA, van de Bruinhorst K, Olson D, Aiyagari V. 904: IMPROVING HAND HYGIENE COMPLIANCE IN HOSPITAL CARE. Crit Care Med. 2015 Dec;43(12 Suppl 1):227-228.

33. Madhavi Z, Mainali S, Narayan R, McDonagh D, Greenberg M, Aiyagari V. A Collosal catastrophe: Toxic leukoencephalopathy in the setting of diet drugs. Presented at the Neurocritical Care Society Annual Meeting, Washington, DC, September 16-18, 2016

34. Panter M, Olson D, Stutzman S, Aiyagari V. Is an Algorithm for Deciding PICC vs. Midline IV Access Superior to Medical Experience? Presented at the Neurocritical Care Society Annual Meeting, Washington, DC, September 16-18, 2016

35. Saherwala A, Stutzman S, Kalia J, Figueroa S, Aiyagari V, Olson D. Exploring Associations between Invasive and Non-Invasive BP Monitoring in Patients Receiving Vasoactive Medication Infusion. Presented at the Neurocritical Care Society Annual Meeting, Washington, DC, September 16-18, 2016

36. Doyle B, Rogers M, Olson D, Aiyagari V. Electronic Health Record (EPIC systems) Tool Facilitates Nurse Handover and Nurse-Led Neurocritical Care Rounds. . Presented at the Neurocritical Care Society Annual Meeting, Washington, DC, September 16-18, 2016

37. Perez C, Tian F, Olson D, Aiyagari V, Stutzman S, Griffin J, Kalia J, Zhang R, Ding K . Dynamic interaction between EEG and ICP: a pilot study based on wavelet coherence. Presented at the American Academy of Neurology Annual Meeting, Boston, MA. April 2017

38. Olson DM, Aiyagari V, Carlisle B, Ho TT, Atem F, Stutzman SE. Eye color does not alter pupilometer readings. Mayo Clinic Neurocritical Care Meeting. Orlando FL. May 2017

39. Olson DM, Aiyagari V, Carlisle B, Ho TT, Stutzman SE. Normative Data of Pupillary Reading in Neurocritical Care Patients. World Federation of Neuroscience Nurses 12th Quadrennial Congress. Opatija Croatia. September 2017

40. Ho TT, Stutzman SE, Atem F, Carlisle B, Olson DM, Aiyagari V. Is Variance in Pupillary Function Associated with Discharge Outcomes?  World Federation of Neuroscience Nurses 12th Quadrennial Congress. Opatija Croatia. September 2017

41. Stutzman SE, Aiyagari V, Hill M, Miller C, Atem F, Olson DM. Incongruence in Constriction Velocity and Neurological Pupil Index. Neurocritical Care Society Conference. Waikoloa, Hawaii. October 2017

H) GRANT SUPPORT

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Sponsor: American Heart Association. Beginning Grant-in-Aid (PI – Venkatesh Aiyagari, MBBS, DM)

Grant no: 0360008Z

Role: Principal Investigator

Title: Autoregulation of cerebral blood flow in acute ischemic stroke

Date: 1/1/2003 – 8/15/2003 (Award given up for competing support with subsequent award)

Goal: The goal of this project is to determine if it is safe to lower blood pressure immediately after an acute ischemic stroke

Sponsor: National Institutes of Health. Program Project Grant (PI – William Powers, MD)

Grant no.: 2 PO1 NS35966-06

Role: Co-Investigator (Project 2)

Title: Autoregulation of cerebral blood flow in acute ischemia

Date: 9/1/97-5/31/08 (left institution on 2/28/2005)

Goal: The goal of this project is to determine if it is safe to lower blood pressure immediately after an acute ischemic stroke

Sponsor: Novo Nordisk, Inc

Grant no: F7ICH-1641

Role: Local site PI

Title: Randomized, double blind, placebo controlled, multi center, parallel groups, confirmatory efficacy and safety trial of activated recombinant factor VII (Novoseven®/Niastase) in acute intracerebral hemorrhage

Date: 4/12-2006-4/13/2007

Goal: The goal of this project is to confirm the safety and efficacy of recombinant factor VII in the treatment of intracerebral hemorrhage

Sponsor: National Institutes of Health. (PI – Colin Derdeyn, MD)

Grant no.: 1R01NS051631-01A2

Role: Local site PI

Title: The role of cerebral hemodynamics in moya moya disease

Date: 9/18/2006-5/31/2011

Goal: The goal of this project is to determine the role of cerebral hemodynamic factors in the pathogenesis of stroke in patients with moya moya disease

Sponsor: National Institutes of Health. (PI – Daniel F. Hanley, MD)

Grant no.: 1U01NS062851-01A1

Role: Local site PI

Title: Clot lysis: Evaluating accelerated resolution of IVH Phase III (Clear III)

Date: 7/01/200-6/30/2012

Goal: The goal of this project is to determine if intraventricular tPA improves outcomes in patients with intraventricular hemorrhage

Sponsors: World Federation of Neurology and World Stroke Organization

Role: PI

Title: Prototype Survey of Diagnostic and Management Capabilities for Neurological Disorders

Date: 9/2011-9/2013

Goal: To conduct a worldwide survey of neurologists to ascertain the diagnostic and management options available for stroke patients in different countries

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