Katie Silasiri



Project 6.1.1: Student Response Sheet IntroductionAnna Garcia was only 38 when she died, meaning that at least one of her body systems was no longer able to support life. The failure of one or more of her body systems may be the result of injury due to an accident or could be the result of an illness or a combination of illnesses. Before we can determine which system or systems failed or what caused the failure which led to her death, we have to learn more about the human body.The human body is an amazing machine composed of many interrelated systems which are in turn composed of cells, tissues, and organs that act independently and interdependently within the body. No individual component of a human body works alone. Components of each system in the body affect or interact with every other system. The body is dependent upon the many interactions between all systems and structures to maintain homeostasis and health. In this activity you will investigate the different body systems that make up the human body and explore all of the ways Anna’s various illnesses affected each body system, potentially resulting in her premature death.Procedure: Look back in your course file and list all of the ways each body system was impacted by the illness or disease Anna Garcia experienced in her life. Reference Autopsy Reports, Medical Histories and past lab activities to help you organize this information. Record any evidence that shows how the illness or disease may have been involved with her untimely death. Be specific about relationships between body systems and illness. You will use this chart to help construct your final timeline that explains how Anna died. You will need to eventually upload this document to your e-portfolio under Anna’s Cause of Death. Part II: Anna’s IllnessesIllnesses’ Effect on System (if applicable)DiabetesSickle Cell AnemiaHeart DiseaseUrinary Tract InfectionCardiovascularHigh blood glucose erodes blood vessels. Fat deposits from high glucose levels can block arteries (possibly lead to stroke)High Blood Pressure (Hypertension) because diabetes damages arteries, making them a target for hardening.Blood clots are a major cardiovascular risk due to the increased hydrophobicity of RBC’s (Sticky). Stroke is a major complication that can arriseHigh Cholesterol and Familial Hypercholesterolemia. Atherosclerosis= The hardening of arteries due to plaques, which are cause by high cholesterol.Heart attacks from clots due to high cholesterol. Strokes can also occur from high cholesterol resulting in plaques forming clots.Tachycardia=high heart rateAn infection can increase heart rate and blood pressure.DigestiveHigh blood glucose levels can cause oral health problems. Errodes blood vessels. Immune system is compromised. Bacteria grows fast, decaying gums and teeth (destroys bone)-Dry mouth, gingivitis, thrush, ulcers, infections, cavities. Can cause problems with eating (Digestion)Bilirubin gallstones - sickle cells die in 20 days; liver breaks down the bilirubin; extra bilirubin can become a gallstone in the gallbladder(bilirubin forms bile)Cholesterol is what aids bile in emulsifying fats due to its amphipathic properties.Waste that isn’t used in digestion is removed through the urinary system. Urination can cause pain durng a UTIImmuneImmune system is compromised due to the erosion of blood vessels.Seen in Oral Health complications, causint bacteria to grow fast. Sickle Cell causes an increase in WBC count. Also can cause the Spleen to enlarge or burst. Cholesterol is a precursor of Vitamin D. Imoprtant with (low ammounts of vitamin D result in) auto immune diseases, diabetes, heart disease, cancer, chronic pain, etc.Increased production of lymphocytes (B & T cells) and antibodies against the bacteria; Inflammatory response (may increase additional UTI and/or damage to urinary tract structures.NervousNeuropathy: Damaged blood vessles causes nerve death due to malnourished nerves. Can result in numbness and tingling.Stroke is another complication (Brain Damage)Sickle Shaped cells cause clots and can lead to Strokes, which can lead to the death of brain tissue. Low oxygen levels can also negatively effect the brain and its functioning. Cholesterol is used in the myelin sheath and is important for synaptic functioning. Memory B cells are controlled by the central nervous system and are used to fight infectionsRespiratoryKetoacidosis can cause gasping breathing due to the body burning fatty acids due to the inability to absorb glucose.Can cause Acute Chest Syndrome, which happens when lung tissue is deprived of oxygen. Pulmonary Hypertension can occur as well. Happens when the arterial pressure in the lungs increases. Shortness of breath and difficulty breathing can be a result of atherosclerosis (difficulty carrying O2) due to high cholesterol and plaque build up in blood vessels. N/AUrinaryKidney Disease can evolve from diabetes. Kidneys can be overworked from filtering too much blood. Waste build up in blood can lead to kidney failure due to the kidneys loosing filtering ability.Slowed blood flow can lead to a slower immune response, delaying the killing of bacteria and resulting in an increased risk for a UTIDamaged blood vessels due to atherosclerosis and hypertension can cause kidneys to not function normally (aren’t as efficient in removing waste)Untreated UTI’s can lead to Kidney infections Sources Used: ................
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