Designing Organic Synthesis
Designing Organic Synthesis
Krishna P. Kaliappan Department of Chemistry Indian Institute of Technology-Bombay Mumbai 400 076 INDIA
kpk@chem.iitb.ac.in
CH-588: Organic Synthesis Course Slides. Instructor: Krishna P. Kaliappan
Role of Synthetic Chemistry
Biology
Synthetic Chemistry
Materials
Medicine Chemistry
CH-588: Organic Synthesis Course Slides. Instructor: Krishna P. Kaliappan
Synthesis: An Ever Challenging and Exciting Science
Introduction Technical terms Why to do synthesis? History of synthesis
Designing synthetic strategy
Retrosynthetic analysis
Practice of total synthesis (analysis and synthesis) Linear and convergent synthesis Examples
CH-588: Organic Synthesis Course Slides. Instructor: Krishna P. Kaliappan
Technical Terms
? Organic Synthesis-means the same as synthetic organic chemistry
? Total Synthesis: The chemical synthesis of a molecule from a relatively simpler starting materials
? Semisynthesis: the synthesis of a given molecule from an advanced precursor related to it
? Formal Synthesis: the synthesis of a key intermediate that has been already converted into the target molecule
? Partial Synthesis: the synthesis of a portion of the naturral product
CH-588: Organic Synthesis Course Slides. Instructor: Krishna P. Kaliappan
Basic Requirements
Knowledge Creativity Artistic Taste Persistence Stamina Experimental Skill Courage and Character
CH-588: Organic Synthesis Course Slides. Instructor: Krishna P. Kaliappan
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