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APRIL 2018

COMMERCIAL INSIGHTS FOR THE C-SUITE

VOLUME 38, NUMBER 4

Wo20m18aHnBoAf the Year

Julie Gerberding

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From the Editor 3

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The New Talent Trajectory

IF YOU HAVE EVER DRIVEN ON THE BACK ROADS OF LANCASTER, PA, you'll see deep ruts on the edge of the roadway caused from the horse-pulled carriages led by the Amish. The ruts have worn the pavement over time. Same principle with the neural pathways in our brain. We do something the same way over and over, and it becomes routine, almost without thought. To create new pathways, you need to change things up and do things differently, which can be easier said than done. This also applies to careers, which used to be long-standing in one company. Now, the average person changes jobs 12 times in their career. In the pharma industry, as noted in the first article of our talent section (see page 16), companies tended to only hire people that were from other pharmas.

B ut that has changed within the past five to six years. Now, executives are seeing an evolving landscape that is creating a need to hire experts from outside of pharma, as well as create new pathways for traditional roles, or roads to another arm of life sciences.

In a recent webcast (), the topic was CRO consolidation, and it covered a lot of ground; suffice to say that issues of venture capital, M&As, and outsourcing were all in the mix. During the Q&A, the question was asked, "When we discuss the increase of expertise and skills in the new `mega' CROs, does this subtly imply that the pharma sponsors run the risk of losing those skills and expertise as they shift more of their workflow to CROs?"

Jeffrey Kasher, president, Patients Can't Wait, and previous to that a 28-year veteran of Eli Lilly, responded, "That's already happened. It started in the preclinical and toxicology space, when all big pharma outsourced those packages. What they've seen over time is they lose that expertise inside and all of a sudden they don't know what good looks like."

He continued, "You lose capabilities, number one, and, number two, you lose your traditional pipeline of developing people. So, I think what you're going to end up seeing is instead of people going from pharma to CROs, you're going to see more of a cycle where people come in and learn at CROs and go work for pharma companies and go back. ... It's not going to be a one-way street anymore."

And it's not only CROs that are gaining more from pharma outsourcing, though development has more penetration at 70%. But with the addition of the "mega" CROs, like the newly renamed Syneos Health and IQVIA, who have added commercial outsourcing capabilities to their mix for end-to-end offerings, it can take advantage of the development relationships sooner in the drug's lifecycle.

If Kasher sees paths from CRO to pharma and back, there is a definite move from pharma to biotech. In our talent section, Senior Editor Michelle Maskaly outlines a few routes that for-

mer pharma executives have taken to reach their new future in biotech (see article on page 20). Recruiters that I interviewed said that the world of biotech, full of venture capital and vision, is a very fertile area for former big pharma executives. But one warned that, if you are going to go to biotech, be prepared to wear many hats and not have access to the larger budgets you might be used to.

Pharma companies are also now more open to hiring outside of life sciences altogether. People who are in consumer goods or retail, or those with digital and data experience, may find the doors of pharma more available than in the past. As noted, GSK's new CEO has hired the former CIO of Walmart and appointed its chief digital officer from Google.

The rest of our talent section this month touches on the new role of data scientist; the revamped role of medical affairs; an uptick in the education of and need for HEOR professionals; and how sponsorship, rather than traditional mentorship, has become more necessary for not only diversity but toward helping create opportunities for a more inclusive company culture.

Pharmaceutical Executive regularly profiles executives in pharma and also biotech, healthcare, and related fields, so we see a lot of career paths and trajectories. Most are not hardened into a single line, but flow and move based on mentors, personal decisions, inspiration, or necessity.

As we continue to cover those C-suite executives, again we are turning our eye to the next generation of pharma leaders. Nominations for our annual Emerging Pharma Leaders are now open. You can submit your nominations at leaders2018.

Who's destined to change the face of pharma? Can you make the tough decisions that face manufacturers? Do you navigate the commercial, financial, scientific, and R&D market landscape with leadership and inspiration? Do you have what it takes to get to the C-suite? Winners will be featured in the October issue of Pharmaceutical Executive.

LISA HENDERSON Editor-in-Chief lisa.henderson@ Follow Lisa on Twitter:

@trialsonline

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PHARMACEUTICAL EXECUTIVE APRIL 2018

VOLUME 38, NUMBER 4

Pharmaceutical Executive's 2018 Editorial Advisory Board is a distinguished group of thought leaders with expertise in various facets of pharmaceutical research, business, strategy, and marketing. EAB members suggest feature subjects relevant to the industry, review article manuscripts, participate in and help sponsor events, and answer questions from staff as they arise.

MURRAY L. AITKEN Senior Vice President, Healthcare Insight, QuintilesIMS

INDRANIL BAGCHI Vice President and Franchise Head, Global Value and Access, Novartis

FREDERIC BOUCHESEICHE Chief Operating Officer, Focus Reports Ltd.

LES FUNTLEYDER Portfolio Manager, Esquared Asset Management

JOHN FUREY Chief Operating Officer, Spark Therapeutics

JAMES J. GALEOTA, JR. (JAY) President and Chief Operating Officer, G&W Laboratories

STEVE GIRLING President, IPSOS Healthcare North America

ADELE GULFO Executive Vice President and Chief Strategy Officer, Mylan

NICOLE HEBBERT Vice President, Patient Access and Engagement, UBC--an Express Scripts Company

MICHELE HOLCOMB Head, Strategy & Corporate Development, Cardinal Health

BOB JANSEN Principal Partner, Zensights LLC

KENNETH KAITIN Director & Professor, Center for the Study of Drug Development, Tufts University

CARRIE LIASKOS Vice President, Market Engagement, Syneos Health

JULIE C. LOCKLEAR Vice President & Head, Health Economics & Outcomes Research, EMD Serono

CHANDRA RAMANATHAN Head, East Coast Innovation Center, Bayer U.S.

BARBARA RYAN Partner, Clermont Partners

SANJIV SHARMA Vice President, North America Commercial Operations, HLS Therapeutics

TERESE WALDRON Director, Executive MBA Programs, St. Joseph's University

PETER YOUNG President, Young & Partners

GROUP PUBLISHER Todd Baker

EDITOR-IN-CHIEF Lisa Henderson

MANAGING EDITOR Michael Christel

EUROPEAN & ONLINE EDITOR Julian Upton

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Table of Contents 5

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Talent

Rewriting Pharma's Talent Blueprint

Lisa Henderson, Editor-in-Chief

Amid rapid shifts in technology and consumer engagement, Pharm Exec explores how new models in hiring and recruitment--along with the evolution of the C-suite--are reshaping biopharma's talent path of the future.

16

2018 HBA WOTY: Unwavering Purpose

Michelle Maskaly, Senior Editor

Pharm Exec profiles Merck & Co.'s Julie Gerberding, this year's winner of the Healthcare Businesswomen's Association Woman of the Year award, who, from her early calling as a doctor to assuming critical leadership roles at the front lines of the world's most pressing population health issues, has remained steadfast in her life's mission--help the many, help the one.

12

Cover photo courtesy of Merck & Co.

Trading Big Pharma for Small Startup

Michelle Maskaly, Senior Editor Senior leaders in the life sciences share stories on making the jump from the pharma to biotech worlds--and the innate drivers behind such moves.

20

Evolving the HEOR Skill Set

Julian Upton, European and Online Editor The advent of health economics and outcomes research (HEOR) training in responding to advancing industry needs.

22

Aesthetics Matter

By Roger Humphrey Building a team isn't just about hiring the right people--offer a workplace that inspires to attract and keep the best talent.

28

NEWS & ANALYSIS

Washington Report

8 Drug Marketing and Advertising Under Fire

Jill Wechsler, Washington Correspondent

Global Report

10 A Plus ?a Change Feeling on European Pharma

Reflector, Brussels Correspondent

Emerging Markets

30 Is China Trending Up? The Four Growth Drivers

By Jin Zhang

STRATEGY & TACTICS

Marketing

32 The New (Augmented) Reality in Life Sciences

By Arno Sosna

Compliance

34 The Top Barriers to Patient Persistence

By Vickie Andros and Jake Caines

Digital Health

36 Staying Ahead of the Curve

By Kal Patel

INSIGHTS

From the Editor

3 The New Talent Trajectory

Lisa Henderson, Editor-in-Chief

Back Page

51 A Watchful Eye on AI

Julian Upton, European and Online Editor

Country Report: Poland

38 Solid Foundations, Grand Ambitions

Focus Reports, Sponsored Supplement

Still motivated by its challenging, underdog past, Poland has strengthened its economic engine in Europe, where the nation's pharmaceutical sector is increasingly pursuing enlightened approaches in areas such as market access and evidence-based decision-making.

PHARMACEUTICAL EXECUTIVE VOLUME 38, NUMBER 4 (Print ISSN 0279-6570, Digital ISSN: 2150-735X) is published monthly by UBM LLC 131 W. First St., Duluth, MN 55802-2065. Subscription rates: $70 (1 year), $125 (2 years) in the United States and Possessions; $90 (1 year), $145 (2 years) in Canada and Mexico; $135 (1 year), $249 (2 years) in all other countries. Price includes air-expedited service. Single copies (prepaid only): $7 in the United States, $9 in all other countries. Back issues, if available, are $20 for the United States and Possessions, $25 for all other countries. Include $6.50 per order plus $2 per additional copy for US postage and handling. If shipping outside the United States, include an additional $10 per order plus $3 per additional copy. Periodicals postage paid at Duluth, MN 55806 and additional mailing offices. POSTMASTER: Please send address changes to PHARMACEUTICAL EXECUTIVE, PO Box 6180, Duluth, MN 55806-6180. Canadian G.S.T. Number: r-12421 3133rt001, Publications mail agreements NO. 40612608. Return Undeliverable Canadian Addresses to: IMEX Global Solutions, P. O. Box 25542, London, ON N6C 6B2, Canada. Printed in the USA.

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