Why are we here - Amyloidosis Support Groups
[Pages:1]Why are we here
Dr. Gertz, Mayo Clinic Your potential to be eligible for a clinical trial. Effective treatments depend on trials. Survey opportunities ? so we can better understand the natural history of this disease There are many Amyloid subtypes. ATTR is about ? of the amyloid that Mayo Clinic sees. Primary amyloid (AL) is about 60% Age at diagnosis ? Mode in the US is in age 61-65, with about half form 56-70, and the rest about evenly divided before and after then (slightly more before) At Mayo, 2/3rd of pts. are men, although the gene is probably present 50/50 in the affected population Age at Sx onset ? mode is 60 yr. old, with about ? 55-60. The delay from Sx to Dx is understandable ? this is a rare disease, and most MDs may only see one patient for diagnosis in their career, so they often do not recognize it. Common symptoms ? Sx vary with ATTR variant. Common Sx are:
peripheral neuropathy,
autonomic neuropathy,
cardiomyopathy, weight loss
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