PDF Liver Cirrhosis: A Toolkit for Patients

Liver Cirrhosis: A Toolkit for Patients

Bring this book to every appointment

Division of Gastroenterology and Hepatology

Table of Contents:

Welcome and Phone numbers .............................................................2

What is the liver?.............................................................................................2 What is liver cirrhosis ...................................................................................4

Treating the complications of decompensated cirrhosis..............6

Preventing bleeding from esophageal varices ..................6 Managing ascites...........................................................8 Managing hepatic encephalopathy................................12 Managing jaundice.......................................................14

Living with Cirrhosis...............................................................................15

Diet ...........................................................................15 Medications ................................................................19 Surgery ......................................................................19 Hospital stays ............................................................19 Screening for liver cancer ............................................19 Vaccination ................................................................20

Your Cirrhosis Toolkit .........................................................................21

My healthcare team .....................................................21 Current Medication List........................................... .....22 My Appointment Planner ................. ...........................25 Weight Log..................................................................27 Schedule for Bloodwork .............................................29

Title page image: "Anatomy of the biliary tree, liver and gall bladder" ?Jiju Kurian Punnoose is licensed under a Creative Commons Attribution 3.0 Unported License.

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Welcome

Welcome to the Cirrhosis Management Program at the University of Michigan. As your healthcare team, we take pride in doing everything possible to maximize your health. However, we cannot do this alone. You, the patient, can make an enormous difference in your health by eating right, taking your medications properly, and taking control of your disease management. This toolkit provides you with the information and tools you need to make informed decisions, avoid hospital stays and ER visits, and improve your quality of life.

To schedule an appointment, call: 888-229-7408

To speak with a nurse, call: 800-395-6431

What is the liver?

The liver is the body's largest internal organ. It is an essential organ and the body cannot survive without it. The liver has many important functions including Preventing infections Removing bacteria and toxins from

the blood Digesting food and processing

medications and hormones Making proteins that help the blood

clot Storing vitamins, minerals, fats, and

sugars for use by the body

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What is liver cirrhosis?

When something attacks and damages the liver, liver cells are killed and scar tissue is formed. This scarring process is called fibrosis (pronounced "fi-bro-sis"), and it happens slowly over many years. When the whole liver is scarred, it shrinks and hardens. This is called cirrhosis, and usually this damage cannot be undone. Any illness that affects the liver over a long period of time may lead to fibrosis and, eventually, cirrhosis. Heavy drinking and viruses (like hepatitis C or B) are common causes of cirrhosis. However, there are other causes as well. Cirrhosis may be caused by a buildup of fat in the liver of people who are overweight or have diabetes. Some people inherit genes that cause liver disease. Other causes include certain prescribed and over-the-counter medicines, environmental poisons, and autoimmune hepatitis, a condition in which a person's own immune system attacks the liver as if it were a foreign body.

What happens when you have cirrhosis?

Cirrhosis causes the liver to become lumpy and stiff. This prevents blood from flowing through the liver easily and causes the build-up of pressure in the portal vein, the vein that brings blood to the liver. High pressure in the portal vein is called portal hypertension. To relieve this pressure, the blood goes around the portal vein, through other veins. Some of these veins, called varices, can be found in the pipe that carries food from your mouth to your stomach (the esophagus) or in your stomach itself.

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Portal hypertension also causes blood to back up into another organ called the spleen. This causes the spleen to get bigger and destroy more platelets than usual. Platelets are blood cells that help in blood clotting. With cirrhosis, blood is blocked from entering the liver and toxic substances that the liver normally filters escapes into general blood circulation.

Aside from the problems with liver blood flow, when cirrhosis is advanced, there aren't enough healthy liver cells to make good substances, such as albumin (a protein) and clotting factors that the liver normally makes. Another complication is Liver cancer, called hepatocellular carcinoma (HCC). This cancer can occur if some of the sick liver cells start to multiply out of control. Liver cancer, may occur in any stage of cirrhosis. There may be no signs of liver cancer until the cancer has grown very large and causes pain.

What are the symptoms of cirrhosis?

The early stage of cirrhosis is called compensated cirrhosis. At this stage you may have no symptoms at all. In fact, a person may live many years with cirrhosis without being aware that her liver is scarred. This is because the pressure in the portal vein is not yet too high and there are still enough healthy liver cells to keep up with the body's needs. But if nothing is done about the cause of cirrhosis (for example, if the person continues to drink alcohol, or if hepatitis or other causes of cirrhosis are not treated), the pressure in the portal vein gets higher and the few remaining healthy liver cells are not able to do all the work for the entire liver.

At that point, you may notice symptoms like low energy, poor appetite, weight loss, or loss of muscle mass. As the disease progresses symptoms become more severe and may be life threatening. Advanced cirrhosis is called decompensated cirrhosis. At this stage you can also develop the following

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