Animal toxins as medicine

    • [PDF File]Animal Venoms in Medicine - Zoltan Takacs

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      Current Medical Application of Animal Venom Toxins Diagnostics Toxins are used in approximately 15 diagnostic assays in clin ical hemostasis laboratories and as a test for myasthenia gravis. All toxins are originated from snake venoms (Table 1). The vertebrate hemostatic system, a delicate interaction


    • [PDF File]Animal Toxins: How is Complexity Represented in Databases?

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      significant proportion of sea anemone and snake toxins. The Swiss-Prot initiative was followed by the establishment of a few databases centered on toxins. Currently, three additional databases are available on the web. These are ConoServer, ArachnoServer and the Animal Toxin DataBase (ATDB). ConoServer [4] specializes in toxins from marine cone


    • [PDF File]Animal Toxins Can Alter the Function of Nav1.8 and Nav1

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      Toxins 2012, 4 621 suggest that these two Nav channel isoforms may also be expressed in tissues such as enteric neurons [7,8], heart [9], retina [10], dental pulp [11], and trigeminal ganglia [11 ...


    • [PDF File]Animal toxins: an overview - ResearchGate

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      bDepartment of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand Toxins in the environment, derived from animals, water and food, are a worldwide problem but much more


    • [PDF File]Use of Animal Venom Peptides/Toxins in Cancer Therapeutics

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      In addition, toxins enhance G0/G1 enrichment upon treatment of cancer cells. Further, encapsulated honey bee, wasp and scorpion venoms exert much potent anti-cancer effect on many cancer cells lines. Upon slight chemical modifications animal toxins could gear up higher selectivity, show much improved target specificity and lesser toxic


    • [PDF File]Animal Toxins Can Alter the Function of Nav1.8 and Nav1

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      Animal Toxins Can Alter the Function of Nav1.8 and Nav1.9 John Gilchrist 1 and Frank Bosmans 1,2,* 1 Department of Physiology, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA; E-Mail: john.gilchrist@jhmi.edu 2 Solomon H. Snyder Department of Neuroscience, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA


    • [PDF File]Editorial Animal Toxins and Their Advantages in Biotechnology and ...

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      Research regarding animal venoms generally focuses on the clinical features of human envenomation, the relation-ship between structure and function of animal toxins, bio-prospection of toxins with potential for the development of therapies,diagnostickitsforhumandiseases, andalternative or complementary therapies for envenomation. erefore,


    • Animal toxins: an overview - Pennsylvania State University

      Animal toxins: an overview Visith Sitprija a, Suchai Suteparak b aQueen Saovabha Memorial Institute, The Thai Red Cross Society, Bangkok 10330, bDepartment of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand Toxins in the environment, derived from animals, water and food, are a worldwide problem but much more


    • [PDF File]From Toxins to Drugs: Chemistry and Pharmacology of Animal Venom and ...

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      Animal venom use in folk medicine is well documented. Its use was reported for Ayurveda medicine, western traditional medicine and Chinese folk remedies [4,5]. ... Annu Amanjot. From Toxins to Drugs: Chemistry and Pharmacology of Animal Venom and other Secretions. On J Complement & Alt Med. 1(1): 2019. OJCAM.MS.ID.000505. DOI: 10.33552/OJCAM ...


    • [PDF File]From Animal Poisons and Venoms to Medicines ... - ResearchGate

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      Bordon et al. Animal Toxin-Based Drug Discovery Frontiers in Pharmacology | www.frontiersin.org 2 July 2020 | Volume 11 | Article 1132 TABLE 1 | Approved drugs and therapies for human use.


    • [PDF File]Animal Toxins Providing Insights into TRPV1 Activation Mechanism

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      animal toxins’ binding sites were found to reside in the outer pore domain. During TRPV1 gating, considerable rearrangements occur in the outer pore, pore helix, and selectivity filter, but not in transmembrane segments 1–4 as would be expected when compared to the structurally-similar voltage gated channels [11,12,20].


    • [PDF File]Animal Toxins Can Alter the Function of Nav1.8 and Nav1

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      Animal Toxins Can Alter the Function of Nav1.8 and Nav1.9 John Gilchrist 1 and Frank Bosmans 1,2,* 1 Department of Physiology, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA; E-Mail: john.gilchrist@jhmi.edu 2 Solomon H. Snyder Department of Neuroscience, School of Medicine, Johns Hopkins University, Baltimore, MD 21205, USA


    • Animal toxins: an overview - ResearchGate

      bDepartment of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok 10330, Thailand Toxins in the environment, derived from animals, water and food, are a worldwide problem but much more


    • [PDF File]Animal Venoms in Medicine

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      Current Medical Application of Animal Venom Toxins Diagnostics Toxins are used in approximately 15 diagnostic assays in clin ical hemostasis laboratories and as a test for myasthenia gravis. All toxins are originated from snake venoms (Table 1). The vertebrate hemostatic system, a delicate interaction


    • [PDF File]Animal Venoms in Medicine

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      Current Medical Application of Animal Venom Toxins Diagnostics Toxins are used in approximately 15 diagnostic assays in clin ical hemostasis laboratories and as a test for myasthenia gravis. All toxins are originated from snake venoms (Table 1). The vertebrate hemostatic system, a delicate interaction


    • [PDF File]Toxic Animal-Based Medicinal Materials Can Be Effective in ... - MDPI

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      Among the toxic animal-based medical materials, Hirudo was the most commonly used in medicinal decoctions [30. 33], followed by bufalin twice [28,29]. According to the eight studies, the underlying mechanisms of animal toxins against endometriosis were as follows: induction of apoptosis [28. 30], inhibition of angiogenesis


    • Why do we study animal toxins? - Bioline

      Evolution links animal toxins with humans Humans originated and live together with venomous animals. During evolution, the ancestors of humans and animal toxins were tightly associated with each other in terms of evolutionary conservation as well as mutual interactions. The natural and inherent links of animal toxins with humans were determined by


    • [PDF File]Animal protein toxins: origins and therapeutic applications - Springer

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      traditional Chinese medicine. Many important effects have been discoveredwhen studying the functionality of animal toxins. The high selectivity and potency make animal toxins as brilliant pharmacological tools and drug candidates. Proteins and peptides are the main active components in animal venoms (Fig. 1), which mostly contain multiple ...


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