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CT and MR findings of systemic lupus erythematosus ...
Page 2 of 15 Learning objectives To learn the spectrum of CT and MR findings of systemic lupus erythematosus involving the brain (CNS lupus). To know how to make the differential diagnosis of lesions of CNS lupus based on lesion

Central nervous system lupus: a clinical approach to therapy
PAPER Central nervous system lupus: a clinical approach to therapy G Sanna1¤, ML Bertolaccini2 and A Mathieu3 1Department of Rheumatology,Homerton University Hospital, LondonE9 6SR, UK; 2Lupus Research Unit, The Rayne Institute, St Thomas’ Hospital,

Alterações na Ressonância Magnética Cerebral nos Pacientes ...
to assess the outcome of treatment in neuropshychiatric SLE patients. Keywords: Systemic Lupus Erithematosus, neuropsychiatric symptoms, seizures, psychosis, …

[PDF File]Managing CNS involvement in systemic lupus erythematosus
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Managing CNS involvement in systemic lupus erythematosus Epidemiology Systemic lupus erythematosus (SLE) is a sys-temic connective tissue disease with a broad range of clinical manifestations characterized by inflammatory and immune-mediated patho - genetic mechanisms. Since the first report of stupor and coma in the 19th century, several

Neuronal and Astrocytic Damage in Systemic Lupus ...
Without treatment, CNS lupus is one of the major causes of morbidity and mortality in SLE. In recent years, CNS lupus has been treated with cytotoxic drugs, which improve the disease outcome (6). The availability of beneficial treatment remedies increases the need for early recognition of CNS manifestations in lupus, as well as an evaluation of

[PDF File]Complications of Systemic Lupus Erythematosus in the ...
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Lupus Erythematosus in the Emergency Department Joanna L. Marco, MD; Christine L. Chhakchhuak, MD Understanding and differentiating common from emergent complications of systemic lupus erythematous assists the clinician in recognizing and making appropriate treatment decisions in this complex patient population. S ystemic lupus erythematosus (SLE)

Corticosteroids in Lupus Nephritis and Central Nervous ...
vous system (CNS) lupus includes corticosteroids in high doses for immunosuppression. Despite the potential to be lifesaving in cases of lupus nephritis and CNS lupus, cortico-steroids are also associated with long-term damage and early mortality. The goal of lupus therapy remains elimination of corticosteroids when possible.

[PDF File]20 and Clinical Features Systemic Lupus Erythematosus ...
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Systemic Lupus Erythematosus: Pathogenesis and Clinical Features 477 disease starts with a preclinical phase characterised by autoantibodies common to other systemic autoimmune diseases and proceeds with a more disease-specifi c clinically overt autoimmune phase (Bertsias et al 2010a).

[PDF File]Paranoia and suicidality after starting treatment for lupus
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treatment for lupus Erin A. Kindred, MD, Stephanie Sutton, MD, and Ashish Sharma, MD CASE Unusual behavior, thoughts Mr. L, age 28, an immigrant from Burma, is brought to his primary care physician’s clinic by his wife for follow-up on a rash. During the evaluation, his wife reports that Mr. L recently has had suicidal ideation, depres-

[PDF File]Treatment of Neuropsychiatric lupus
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In patients with lupus all headache types was not different from controls . Usually it does not require further investigation and it should be classified according to IHS criteria and managed as a primary headache . Headache might be the heralding symptom of a more complex CNS syndrome. Brain127,1200–1209 (2004).

Cns lupus treatment