Fatty acid synthase pathway
Abstract - ResearchGate
Horiguchi A, Asano T, Asano T, Ito K, Sumitomo M, Hayakawa M. Fatty acid synthase over expression is an indicator of tumor aggressiveness and poor prognosis in renal cell carcinoma. The Journal of urology. 2008; 180: 1137-40.
[DOC File]Stage (Location) - UCSB
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6. Endogenous fatty acid/TAG generation in breast alveolar cell: fatty acids are made by acetyl CoA via acetyl CoA carboxylase, fatty acid synthase, and thioesterase II. This makes medium chain fatty acids which are then incorporated into triacylglycerol molecules for …
Fatty acid synthesis - Wikipedia
Palmitate (16:0), the normal product of the fatty acid synthase pathway, is the precursor of longer chain saturated and unsaturated. fatty acids through the actions of elongases and desaturases-Elongases are present in both the mitochondrion and the ER but the mechanisms differ to add or remove carbons
[DOC File]Chapter 25
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B) Fatty acid synthesis occurs in the mitochondrial matrix and β-oxidation occurs in the cytosol. C) The carboxylation of acetyl CoA to malonyl CoA is the committed step in β-oxidation. D) The fatty acid chain is elongated by 3 carbons during each round of synthesis. E) FAD and NAD+ are co-factors in fatty acid synthesis, while NADPH is a co ...
[DOC File]Biochemistry Objectives 51 - University of Arizona
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4. Consider the role of the pantothenic acid groups in animal fatty acyl synthase and the size of the pantothenic acid group itself, and estimate a maximal separation between the malonyl transferase and the ketoacyl-ACP synthase active sites. Answer: In fatty acyl synthase, pantothenic acid is attached to a serine residue as shown below.
[DOC File]Role of Insulin and Glucagon in the regulation of metabolism
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Fatty Acids. Glycerol Glucose (monosaccharides) Phe as example (Amino Acids) 2 Formation of Acetyl-CoA acyl-CoA synthase ↓ CoASH → ADP, HPO42- glycerol kinase ↓ ATP, Mg2+ → ADP hexokinase ↓ ATP, Mg2+ → ADP phenylalanine hydroxylase ↓ fatty acid acyl-CoA (a thioester) glycerol-3-phosphate glucose-6-phosphate
[DOC File]Exam #1
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Fatty acid synthase. FAS inhibitors orlistat, cerulenin, CM-55 and C75. ... tumor cells used the fermentative pathway from glucose to lactic acid in a much higher proportion than normal cells ...
[DOC File]Cellular Biochemistry Notes
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↑ activity of fatty acid synthase ↑ activity of lipoprotein lipase. Uptake of glucose into muscle and adipose tissue ↑ recruitment of GLUT4 glucose transporters to the plasma membrane of muscle and fat cells. Describe how glucagon stimulates glycogen breakdown, gluconeogenesis and fatty acid oxidation. Glycogenolysis. inhibits glycogen ...
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