Glucocorticoid mechanism of action
Glucocorticoids: List, Uses, Side Effects, and More
Glucocorticoid hormones (GCs) are pleiotropic hormones essential in all aspects of human physiologic functions in health and disease. They regulate a variety of essential biological functions.
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They all have the same mechanism of action . Glucocorticoid effects; which are incorrect (question may have been slightly different?) increased protein catabolism – correct. increased glucose 6 phosphatase – yes. increased transamination / deamination of amino acids – probably.
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Glucocorticoid Excess - has . fat redistribution - glucocorticoids work peripherally, insulin better centrally. Appearance - patient will have thin arms & legs, but fat torso. Mechanism - glucocorticoids induce . hyperglycemia ( insulin released, but works best central. Clinical Administration - can be given orally/parenterally, topically, or ...
[DOC File]glucocorticoid enhancing-effect of modafinil, in control ...
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Mechanism of Action: affects fluid and electrolyte balance. Uses: Addisons Disease. Salt losing adrenogenital syndrome. Examples: Desorycortisone (DOCA) IM Florinif PO. synthetic potent mineralocorticoid and weak glucocorticoid, Action. Helps retain sodium, increases blood pressure in Addison's Disease and adrenogenital syndrome. Side effects ...
[DOC File]PRINCIPLES OF CELLULAR FUNCTION - Doctorswriting
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Mechanism of Action. Anti-Tuberculosis Drugs. Tuberculocidal. Isoniazid . CYP450 Inhibitor . Metabolize through acetylation, highly genetic polymorphism . Side Effects . Peripheral neuropathy – supply Vit B6. Hepatotoxic . Mycolic Acid synthesis inhibitor . Spectrum of Activities . Kill extracellular bacteria . Weakens intracellular bacteria ...
[DOC File]Curvitae JHU promotion 2000 - Hopkins Medicine
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(Classify the drugs, explain their mechanism of action and justify your conclusion)? (15) Loratidine: H1-R antagonist. Prednisone: Glucocorticoid R agonist. Glucocorticoid Rs are nuclear receptors/transcription factors => responses mediated via transcriptional modulation => requires time => H1-R antagonists act quicker
[DOC File]PRINCIPLES OF CELLULAR FUNCTION - Doctorswriting
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They all have the same mechanism of action . Glucocorticoid effects; which are incorrect (question may have been slightly different?) increased protein catabolism . increased glucose 6 phosphatase . increased transamination / deamination of amino acids . increased peripheral glucose utilisation .
[DOC File]PRINCIPLES OF CELLULAR FUNCTION - EmergencyPedia
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Insulin is synthesised as a prohormone Which of the following does not utilise the same receptor in its mechanism of action insulin (tyrosine kinase) Glucocorticoid effects (↑ protein catabolism;↑ glucose 6 phosphatase;↑ trans/deamination of amino acids;↓ glycogen synthetase); which are . incorrect. increased peripheral glucose utilisation
[DOC File]3-03-08 Adrenal Physiology & Pharmacology
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Indeed, owing to both fat and protein mobilization, the primary mechanism of glucocorticoid effect is likely to enhance the rate of glucose production in the liver (Shephard 1987), and to increase plasma glucose, as well as glycerol and fatty acids concentrations, in the same manner as epinephrine does (Cerretelli 2002).
[DOC File]NUR 312: Pharmacology in Nursing II
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Stellato C. Blockade of chemokine production/function as an example of glucocorticoid anti-inflammatory actions. In: Inhaled Steroids in Asthma—Optimizing effects in the airways. RP Schleimer, O'Byrne PM, Szefler SJ, and R Brattsand, editors.
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