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[DOCX File]Australian public assessment for lixisenatide
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Oral administration of alogliptin to normoglycaemic rats, dogs, and monkeys effectively inhibited plasma DPP-4 activity. Toxicokinetics were performed in the monkey mechanistic study and 90% inhibition over the first 3 h was achieved at 1.7 mg/kg single oral dose which achieved an exposure 1.3 times the anticipated clinical AUC 0-24h .
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[DOC File]Primary Species – Dog (2007)
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Single-dose toxicity studies were conducted by the SC and IV routes in mice (≤500 μg/kg), rats (≤5000 μg/kg) and dogs (≤200 μg/kg SC and ≤100 μg/kg IV), and revealed no mortality or other notable findings apart from effects on body weight in rats (inhibition of body weight gain or small loss of body weight).
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Universiteit Utrecht
Tibial plateau leveling osteotomy (TPLO), esp. in large dogs; lateral fabellar surgery, esp. in small dogs Buckley et al. 2009. Massive transfusion and surgical management of iatrogenic aortic laceration associated with cystocentesis in a dog.
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[DOC File]STATIN-FIBRATE REPORT: Focus on Safety
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Neutrophilic patients, with a count greater than 12 x 109/l, controlled for sex and age, had a shorter survival time (p = < 0.01). In dogs, neutrophilia at presentation predicted a poor outcome, whereas the other haematological parameters were not prognostically informative.
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[DOC File]Fellowship examination in Veterinary Radiology 2001
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Small bowel obstruction is a known possible complication of jejunal feeding tubes in people but has not been reported in dogs.13,14,30-32 In people, the majority of obstructions were associated with older pigtailed catheters that led to intestinal intussusception in up to 15% of patients.13,24 It was speculated that pigtailed tubes would embed ...
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Pancreatitis in Dogs - Symptoms, Causes and Treatment
Discuss the usefulness of imaging studies in the evaluation of a dog suspected of having pancreatitis. Specific learning outcomes being tested: 2,4,7,8 Apportioned assessment: Factual: 20%
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[DOCX File]*Linda Morrison, BVMS, FRCPath, DiplECVP, MRCVS
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There is a small increase in uterine artery vascular resistance in Type 1 diabetes27 which is likely to reflect pre-gestational vasculopathy. It has been proposed that some of these alterations originate from inadequate opening of the spiral arteries by a too shallow
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[DOCX File]Australian public assessment report for Alogliptin (as ...
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Although clinical outcomes were measured, DAIS was not powered to observe a reduction in clinical outcomes. Patients on fenofibrate experienced less atherosclerotic progression (e.g. smaller increase in percent diameter stenosis and smaller decrease in minimum lumen diameter p=0.02, p=0.029, respectively) in the fenofibrate versus the placebo ...
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[DOCX File]www.research.ed.ac.uk
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Some authors advice to take one additional blood sample instead of the two as mentioned before after 20 and 40 minutes.4, 7, 10 Especially, for small breed dogs, in non-cooperative dogs, and dogs with coagulation disorders it would be a great advantage if one additional blood sample instead of two is sufficient to establish a reliable diagnosis.
can a dog survive pancreatitis

Pancreatitis outcomes in small dogs