Physiologic excreted activity
[DOC File]C H A P T E R 6 2
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Thus, CCK has some gastrin activity. The minimum fragment of CCK necessary for its biologic activity is the C-terminal heptapeptide [CCK-7]. CCK is secreted by the I cells of the duodenal and jejunal mucosa in response to two types of physiologic stimuli: monoglycerides and fatty acids (but not triglycerides), and . small peptides and amino acids.
Form A
The absorbed fluoride is distributed throughout the body via the circulatory system. Fluoride becomes incorporated systemically into the saliva, which continuously releases trace amounts of fluoride to the outer surfaces of erupted teeth. Some becomes incorporated in the unerupted teeth; and excess fluoride is excreted in the urine.
[DOC File]An evaluation of the activity of twice-weekly rifapentine ...
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Activity in the mouse model of once-weekly regimens including rifapentine and moxifloxacin during and after 6 months of treatment[18] ... CYP2C9, CYP2C19, or CYP1A2. The sulfate conjugate (M1) accounts for 38% of the oral dose, and is excreted in feces; about 14% of an oral dose is converted to the glucuronide conjugate (M2), and is excreted in ...
[DOC File]CHAPTER 79
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Thus, about 90 per cent (900 mg/day) of the daily intake of calcium is excreted in the feces (Figure 79-3). Almost all the calcium in the body (99 per cent) is stored in the bone, with only about 0.1 per cent in the extracellular fluid and 1 per cent in the intracellular fluid.
[DOC File]Nursing pharmacology - Al al-Bayt University
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Hepatic metabolism involves the activity of a very large class of enzymes as cytochrome P-450 enzymes. ... Drugs that have been made water soluble in the liver are often readily excreted from the kidney by glomerular filtration. ... The immaturity of organs is the physiologic factor most responsible for differences in the pharmacokinetic and ...
[DOC File]ODESSA STATE MEDICAL UNIVERSITY
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Historically more old is the humoral or chemical regulation mechanism. Humoral regulation - the regulation of physiologic processes, that takes place with the help of biologically or physiologically active substances, that are excreted into liquid environment of an organism. Hormones are included into them.
[DOC File]PHARMACOKINETICS
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Or: much of the drug undergoes metabolism, and the metabolites are excreted into urine “Compartmental” analysis - Based on model for physiologic processes - Observed data are fit to model; parameters such as AUC and Cmax are then calculated, assuming the model is correct - Less commonly used, because real-life data may not support model ...
[DOC File]Caveat: The following synopsis of normal liver physiology ...
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There are many substances which are first modified by the liver before being excreted by the kidney. Other substances are modified by the liver and then excreted by the liver into the bile. Included among the substances excreted by the liver are various hormones, such as the steroids. The liver is also a major organ in the excretion of calcium.
[DOC File]RENAL - ACID BASE – ADRENAL PHYSIOLOGY
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Jul 17, 2012 · The activity of the Na-K pump in the Loop of Henle decreases. 21. Which of the following returns closest to normal during chronic respiratory acidosis? ... c. the amount of ammonium ion excreted is reduces as urine pH increases. ... Proteins tend to have a negative charge at physiologic pH. Extracellular fluid constitutes 40% if the total body ...
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