The importance of clinical significance
[PDF File]Statistical Significance - Statistics Improves Health Care
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CLINICAL SIGNIFICANCE OF ALPHA-FETOPROTEIN 87 tients undergoing drug therapy, although newer, more effective drugs may even tually make this an important laboratory adjunct to the follow-up care of such pa tients. In understanding the significance of elevated AFP levels in patients with germ cell tumors of the ovary, testis, or
[PDF File]Differentiating statistical significance and clinical ...
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2. Statistical significance does not equal clinical importance. It only tells us that the observed differences in the outcome are unlikely to be due to "chance alone." This may be a useful first step in evaluating the importance of the observed differences, but it is important to examine the clinical importance of the observed differences.
[PDF File]P Values, Statistical Significance & Clinical Significance
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Clinical Significance • Marker of the effectiveness of an intervention, taking into account practical importance of treatment effects • Gives meaning to observed changes, in terms of implications for patient care • Comparative metric of treatment effectiveness between studies
[PDF File]The Clinical Significance of Patient-Reported Outcomes
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Nursing Research 101 Differentiating. statistical. significance. andclinical. significance. ByElizabethHeavey,PhD,RN,CNM . T. O IMPLEMENT. evidence-based practice, nurses must be able to comprehend and interpret research. That means you need to understand the distinction between statistical significance and clinical significance.
Clinical significance - Wikipedia
P Values, Statistical Significance & Clinical Significance When looking at the results of a research study, a practitioner has to answer two big questions: 1. Were the results due to chance? 2. Are the results big enough to matter to a patient? P values and Statistical Significance
Statistical Significance Versus Clinical Importance
synonymous with CS were the terms clinical importance, clinical relevance, and clinically meaningful. While these terms were interchanged with CS, it is notable that CS was used more exclusively when quantification, numbers or measures were applied to explain the importance of the fmding; this observation is further described in subsequent ...
CLINICAL, SIGNIFICANCE AS IT RELATED TO EVIDENCE BASED
Clinical significance is an important concept in research, particularly in education and the social sciences. The present article first compares clinical significance to other measures of “significance” in statistics. The major methods used to determine clinical significance are …
[PDF File]The clinical significance of human alpha-fetoprotein
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Using CI and minimal clinical importance difference (MCID), we can know the clinical significance of the study. MCID is a statistical method that defines the smallest change in a treatment outcome that a patient would identify as important. Study is clinically significant when it is 95% CI is higher than MCID.
[PDF File]Clinical Significance 1 Running Head: CLINICAL ...
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Clinical Importance of Drug-Drug Interactions Involving Antidiabetic Drugs Sean Hennessy, Pharm.D., PhD. ... clinical significance •Conduct in vitro, invivo, in silico, in populo (epidemiologic) studies • Identify clinical outcomes & significance of the suggested DDIs .
[PDF File]Clinical Importance of Drug-Drug Interactions Involving ...
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its surroundings, statisticians collaborate with health-care researchers to extract information from data, leading to treatments and information that reach the public more quickly. “Statistics Improves Health Care” is part of Statistical CARE: Significance, a series from the American Statistical Association
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