Types of clotting disorders
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Von Willebrand disease (VWD) is a genetic disorder caused by missing or defective von Willebrand factor (VWF), a clotting protein. VWF binds factor VIII, a key clotting protein, and platelets in blood vessel walls, which help form a platelet plug during the clotting process.
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– disorder of the blood; insufficient clotting factors can lead to significant blood loss from minor injuries. All cells have genetic markers on their surfaces that allow the body to recognize itself. Blood types. like ABO, +/- are determined by markers found on red blood cells.
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Clinically: mild form bleeding disorder, associated with nosebleeds, bruising, increased surgical bleeding, and excessive menstruation. Clotting factors are OK but platelet function is not. Three types: Type 1: Low levels of von Willebrand’s factor, but the protein is normal. Autosomal dominant, clinically mild
[DOC File]Emergency Care and Transportation of the Sick and Injured ...
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HEART DISORDERS. Cardiomegaly (Enlarged Heart) ... – decrease in VW factor or its function that causes abnormality in the platelet’s role in clotting. “Acquired” VWD appears in association with autoimmune and immune system diseases such as monoclonal gammopathy, myeloproliferative disorders and others. ... three broad types of hepatitis ...
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Congenital disorders e.g. Thrombocytopenia with absent radii (TAR), May-Hegglin anomaly rare Diagnosis made from clinical history, physical findings, peripheral blood count/film, bone marrow Treatment: treat underlying cause; platelet concentrates when necessary
[DOCX File]Hemophilia is an inherited blood clotting disorder that ...
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Clotting disorders: A group of conditions of the blood clotting (coagulation) system in which potentially dangerous blood clots can form. Cancer A disease that develops when cells in a part of the body begin to grow out of control. Types of cancer include breast, bone, bladder, brain, leukemia, lymphoma. Cardiovascular condition
[DOC File]Platelet and Coagulation Disorders - Josh Corwin
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Vascular disorders. Massive tissue injury. Laboratory Diagnosis. PT, PTT and TT are prolonged. Platelet count is reduced. Fibrinogen is decreased. FDP’s are increased. Blood film shows fragmentation, polychromasia (Haemolysis) (MAHA) Treatment. Treat the underlying disorder. Replacement therapy i.e. clotting factors (FFP), platelets and red cells
Types of Blood Clots
Acute and uncompensated DIC- Clotting factors are used more quickly than the body can replace them. Hemorrhage is predominant and overshadows thrombosis Chronic and compensated DIC- Body keeps up with clotting factor consumption, thrombosis is predominant
[DOC File]HAEMOTASIS III – Coagulation Disorders (Inherited)
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There are two types of hemophilia. Type A and B. The type depends on the clotting factor that is missing. There are thirteen clotting factors needed in the blood for normal clotting to occur. Type A hemophilia is missing factor VIII and type B is missing factor IX and is also called Christmas disease. __Child’s Name_____ has type ____.
[DOC File]Coagulopathy
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b. Hemostatic disorders. i. Bleeding and clotting abnormalities 2. A basic understanding of the hematopoietic system and hematologic disorders will help you to respond to these kinds of emergencies. a. The hematopoietic system consists of organs and tissues involved in the production of blood components. i. Primarily bone marrow, spleen, and ...
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