Whole body cooling in neonates
[DOC File]Rajiv Gandhi University of Health Sciences Karnataka
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All but three Infants underwent whole body cooling. The mean (SD) rectal temperature from 6 to 72 h of the cooling period was 33.57°C (0.51°C). The daily encephalopathy score fell from 11 (6–15), 9.7 (5–14), 8 (5–13) and 7 (2–12) on days 1–4 days after birth, respectively. 51% of the infants established full oral feeding by 9 (4–24) days. 26%
Chapter 16 Prof Hoek - South African Medical Association
Whole body or head cooling should be done under supervision of a paediatrician. Initiate within 6 hours of birth to maintain rectal (core) temperature at 33–34ºC for 72 hours. Slowly rewarm at a rate of 0.5ºC/hour until axillary or skin temperature is at 36.5–36.8ºC.
[DOC File]Homepage of the neonatal neuroscience research group …
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1) Systemic cooling without any efforts to achieve a temperature difference between head and rest-of-the body by cooling the head and to add radiative heat to the rest-of-the body. 2) Regulatory end-point is T rectal 33-34°C, a mean of 33.5 °C. 3) Routine analgesia and sedation in both groups with morphine.
[DOCX File]SHANDS AT THE UNIVERSITY OF FLORIDA
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Servo controlled cooling unit (see Appendix for Quick Start Instructions) ... Monitoring and care during body cooling. Cluster care and minimize stimulation as much as possible. ... Whole-Body Hypothermia for Neonates with Hypoxic-Ischemic Encephalopathy. N Engl J …
[DOCX File]Eprints
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According to Jacobs et al. (2013), two trials looked at selective head cooling instead of whole body cooling; however due to loss of follow up long term risks and benefits could not be ascertained. Whole body cooling was shown to offer a 25% reduction in death or severe neuro-disability by 18 months of age.
[DOC File]Inducing Hypothermia in Neonates on Extracorporeal ...
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Cooling a patient leads to a reduction in enzyme reactions and Ca 2+ signaling needed for platelet activation [3]. The greater the drop in core body temperature the greater the impact on the enzyme reactions and the Ca 2+ signal, and thus a greater the risk of bleeding [3].
[DOC File]Management of Infants with Moderate or Severe Perinatal ...
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3. Azzopardi D Et al. TOBY study. Whole body hypothermia for the treatment of perinatal asphyxial encephalopathy: Randomized controlled trial. BMC Pediatrics 2008, 8:17. 4. Jacobs SE et al. Cooling for newborn with hypoxic ischaemic encephalopathy: Cochrane database of systematic review. 2007, Issue 4, Art No.: CD003311. DOI: 10.1002/14651858.
CNN Research Meeting 2010 - Canadian Neonatal Network
One centre in the US is currently recruiting preterm infants 32-35 weeks GA with HIE in a pilot trial of selective head cooling, but whole body cooling for HIE has not been studied in this population till date. Hypothesis: Controlled whole body hypothermia at a target core temperature of 34°C±0.5°C (34°C-35°C) for 72 hours, started within ...
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