Benzyl alcohol toxicity in adults
[DOC File]GUIDELINE FOR GOOD CLINICAL PRACTICE
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Aug 12, 2003 · Benzyl alcohol lotion: Recommended for children > 6 mo. It kills the adults but not the eggs. Can cause irritation. Lindane shampoo 1%: Can cause neurologic toxicity in immunocompromised or vulnerable patients: premature infants, women pregnant or breastfeeding, HIV patients, people w/ sores, elderly, and underweight people (
[DOC File]Stanford University
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Uncorrected pernicious aplastic or normocytic anemias (neurological damage will progress despite correction of hematological abnormalities). Preparations containing benzyl alcohol should not be used in newborns. Onset/Peak/Duration: Onset: 30-60 min. Peak: 1 hour. Duration: unknown Key Patient Teaching Points:
[DOCX File]New generic antiretroviral products (2016)
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The toxicity of some excipients may vary across pediatric age groups and between pediatric and adult populations, e.g., benzyl alcohol is toxic in the preterm newborn. Depending on the active substance and excipients, appropriate use of the medicinal product in the newborn may require a new formulation or appropriate information about dilution ...
[DOCX File]Veterinary Medicines Directorate
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150mg benzyl alcohol, 3250mg macrogol 300, 1210mg absolute ethyl alcohol, citric acid and polysorbate 80. Intraventricular administration by Ommaya-Rickham reservoir. Sub-group analysis of 68 patients enrolled on the HIT-REZ-97 study (unable to locate this …
[DOC File]Pharmacy Benefits Management Services Home
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Benzyl alcohol (E1519) 220.0 mg. Butylhydroxytoluene (E321) 0.8 mg. ... In adults transient adverse reactions may occur at 3 times the recommended dose. ... bioaccumulative and toxic (PBT) substance. In particular, in acute and chronic toxicity studies with algae, crustaceans and fish, moxidectin showed toxicity to these organisms, yielding the ...
[DOCX File]Form for submission of comments - EFPIA
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Benzyl alcohol toxicity: Spinosad topical suspension contains benzyl alcohol and is not recommended for use in neonates and infants under the age of 6 months. Systemic exposure to benzyl alcohol has been associated with serious adverse reactions, including “gasping syndrome,” and death in neonates and low birth weight infants.3
Benzyl alcohol - Wikipedia
In addition, children, adolescents and adults are exposed daily to benzyl alcohol, as it is a natural constituent of a number of plants. It occurs, for example, in some edible fruits (up to 5 mg/kg). The toxicity of benzyl alcohol has been studied extensively, including acute, short-term and long-term toxicity, carcinogenicity, genotoxicity and ...
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