Lupus like disease
What treatments are available for lupus?
Several different types of medicines treat lupus. Your doctors and nurses may change the medicine they prescribe for your lupus as your symptoms and needs change. Nonsteroidal anti-inflammatory drugs (NSAIDs). Over-the-counter NSAIDs, such as ibuprofen and naproxen, help reduce mild pain and swelling in joints and muscles. Corticosteroids.
What are the causes of lupus?
The cause of lupus in most cases, however, is unknown. Some potential triggers include: Sunlight. Exposure to the sun may bring on lupus skin lesions or trigger an internal response in susceptible people. Infections. Having an infection can initiate lupus or cause a relapse in some people.
What are the types of lupus?
Lupus that only affects the skin is less common and is called cutaneous lupus erythematosus (CLE). There are three types of CLE – discoid lupus, subacute cutaneous lupus, and acute cutaneous lupus. Neonatal lupus and drug-induced lupus are the least common types of lupus.
What are the symptoms of lupus?
It can cause pain, tingling, and numbness in the hand and fingers. Lupus often causes myalgia, or aches and pains in the muscles. Less often, lupus can cause myositis, or inflammation in the muscles — usually in the hips, thighs, shoulders, and upper arms. The most common symptom of myositis is muscle weakness.
[PDF File]Lupus Information Sheet - Veterans Affairs
https://info.5y1.org/lupus-like-disease_1_3d78ef.html
Lupus is a chronic, autoimmune disease that can damage any part of the body (skin, joints, and/or organs inside the body). Chronic means that the signs and symptoms tend to last longer than six weeks and often for many years.
Lupus anticoagulants, anticardiolipin antibodies, and ...
a lupus anticoagulant (LA) or an abnormal anticardiolipin antibody (ACA). Four patients had lupus or a lupus-like illness, three had drug-induced lupus, and 16 had no overt evidence of collagen-vascular disease. Cerebral ischemic events were multiple in 71% of the patients; two patients presented with multi-infarct dementia.
[PDF File]Mouse models of lupus: what they tell us and what they don t
https://info.5y1.org/lupus-like-disease_1_6f12bd.html
Lupus is a complex heterogeneous disease characterised by autoantibody production and immune complex deposition followed by damage to target tissues. Animal models of human diseases are an invaluable tool for defining pathogenic mechanisms and testing of novel therapeutic agents.
[PDF File]Interferon pathway in SLE: one key to unlocking the mystery ...
https://info.5y1.org/lupus-like-disease_1_7a1531.html
The reasons behind the IFN signature in SLE are (1) the existence of endogenous IFN inducers, (2) activation of several IFN-producing cell types, (3) production of many different IFNs, (4) a genetic setup promoting IFN production and (5) deficient negative feedback mechanisms.
[PDF File]Wondering if it is Lupus? - Lupus Foundation of America
https://info.5y1.org/lupus-like-disease_1_4be228.html
Wondering if it is Lupus? Lupus is a serious disease that causes your body to attack itself. Lupus is a disease that affects the immune system, which protects the body from germs and infections. In a person with lupus, the immune system can’t tell the difference between these germs and the body’s healthy tissues and organs.
[PDF File]BCAP promotes lupus-like disease and TLR-induced IFNα ...
https://info.5y1.org/lupus-like-disease_1_a168dd.html
PI3K (BCAP) promoted many aspects of TLR7-driven lupus-like disease including Isg15 and Ifit1 expression in blood and an immature pDC phenotype associated with higher IFN production. BCAP-/-mice produced significantly less serum IFNa than WT mice after injection of TLR9
[PDF File]Living with systemic lupus erythematosus in 2020: a European ...
https://info.5y1.org/lupus-like-disease_1_d12c27.html
as duplicate records, 54 declared they had no lupus, 29 reported drug-induced lupus,5 342 had cutaneous lupus erythematosus (CLE) only, 256 selected the “lupus-like disease” option (no formal lupus diagnosis) and 251 did not mention any specific diagnosis. The remaining 4375 participants reported having physician’s diagnosis of SLE
[PDF File]Lamotrigine induced lupus like syndrome: a case report and ...
https://info.5y1.org/lupus-like-disease_1_a461d0.html
Lupus syndrome induced by thisdrug is rare.1We report a case of lamotrigine-inducedlupus-like syndrome, presented with arthralgias andraised antinuclear antibodies (ANA) titers. CASE REPORT 39-year-old male presented with arthralgias forabout a year in November 2009 (Table 1).
[PDF File]Inhibition of EZH2 ameliorates lupus-like disease in MRL/lpr
https://info.5y1.org/lupus-like-disease_1_403908.html
epigenetic changes in lupus CD4+ T cells. In this study, we sought to determine if inhibiting EZH2 ameliorates lupus-like disease in MRL/lpr mice. Methods: EZH2 expression levels in multiple cell types in lupus patients were evaluated using flow cytometry and mRNA expression data. Inhibition of EZH2 in MRL/ lpr
[PDF File]Could You Have Lupus? - Lupus Foundation of America
https://info.5y1.org/lupus-like-disease_1_990291.html
Lupus is a chronic autoimmune disease that causes inflammation in various parts of the body. The disease can range from mild to life-threatening. Ninety percent of those diagnosed with lupus are females between ages 15 and 44, but lupus also occurs in men, older people, and children.
[PDF File]Lupus Fact Sheet - Lupus Research Alliance
https://info.5y1.org/lupus-like-disease_1_cbee7d.html
Systemic lupus erythematosus (SLE), commonly referred to as lupus, is a debilitating autoimmune disease that affects each person differently and can change over time. This complexity makes it one of the hardest diseases to diagnose and treat.i What goes wrong with the immune system?
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