Statin induced polymyositis
[DOC File]Membership of the Royal Colleges of Physicians of the ...
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E polymyositis. Metadata. Domain= SCE Items. Topic= H.Neurology\13.Myopathy\6.Drug-induced myopathy. Objective=n/a. Item Status= Dataloaded. Keywords= 3583. Custom Item Label= 3583. Current Activity= n/a. Item Editor= Legacy Item Editor (J#) Template= Multiple Choice. Comments. n/a. Dimensions. Groups= Diagnosis. Groups= Interpretation. Groups ...
[DOCX File]University of Manchester
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The patient has the features of a statin-induced immune-mediated necrotizing myopathy (IMNM), recently described as being associated with the anti-HMGCR antibody. First-line immunotherapy with glucocorticoids is appropriate while further investigations are undertaken, although many cases of IMNM ultimately require more aggressive immunotherapy.
[DOCX File]MRCP Notes Compilation - Nigel Fong - Notes Site - Home
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(type V glycogen storage disorder) presents with exercise-induced muscle pain and stiffness with contractures that subside at rest. CK is elevated. Myoglobubinuria can occur. In normal patients there is a sustained increase in serum lactate after exertion but this does not occur in this syndrome. Diagnosis is confirmed by muscle biopsy.
[DOCX File]Title: Statin Induced Autoimmune Myopathy
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As such, it may be appropriate that statin-induced autoimmune myositis should be classified according to the criteria for adult dermatomyositis (DM) and polymyositis (PM) (17,18), which include symmetrical muscle weakness, proximal muscle involvement and elevated serum CK levels. Given that, to date, the anti-HMGCR
[DOC File]Rheum Tips For Int Med Boards
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A Quick Summary of Key Rheumatic Diseases [Bracketed numbers refer to linked MKSAP Board Review questions] Osteoarthritis Rx [3, 8, 13, 37] Initial Rx 2cd 3rd 4th Tylenol
[DOC File]A 48-year-old man comes to the clinic with symptoms of ...
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The most common cause of this in men is probably medication induced, however, he is on no medications. ... Therapy with a statin drug (choice C) is not appropriate at this time. ... Polymyositis (choice D) is a skeletal muscle disorder that is characterized by progressive proximal muscle weakness. Patients often complain of difficulty climbing ...
[DOCX File]Australian public assessment for...
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At 2.5 years, only 66% of the patients allocated to ezetimibe/simvastatin 10/20 mg were taking at least 80% of the study medication and another 6% were taking a non-study statin; in addition, 9% of the patients allocated to placebo were taking non-study statin.
University of Michigan
- In the absence of an action potential, ACh vesicles spontaneously leak into the NMJ and cause very small depolarizations (~0.5mV) in the postsynaptic membrane = the smallest possible depolarization which can be induced in a muscle.
[DOC File]University of Pittsburgh
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Adult polymyositis (PM) and adult dermatomyositis (DM) 2. 1.2. Inclusion body myositis (IBM) 3. 1.3. STATIN MYOPATHY 4. 2.0. Conclusion 8. bibliography 9 Introduction. Skeletal muscle is a dynamic and complex tissue that is composed of many structural proteins and metabolic pathways. Myopathy refers to a disorder of the skeletal muscle.
[DOC File]Neuromuscular Questions
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Polymyositis. Dermatomyositis. Inclusion Body Myositis. Statin Myopathy. Vasculitis has been associated with all the following except: Amphetamine use. Polyarteritis nodosa. Rheumatoid . Wegener’s granulomatosis. Polymyalgia rheumatica. The following are true in GBS electrophysiological studies except. Slowing of peripheral conduction velocity
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