Topical hemostatic agents in surgery
[DOC File]The Chief’s Story
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Mechanical hemostatic material prevent blood loss by forming a mechanical barrier and are usually in the form of powder, sponges, sheets, or micro particles, while active agents such as thrombin to enhance the effectiveness of wound healing by directly participating in the process of fibrin clot formation.
[DOCX File]Christina Fasulo - Welcome
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Topical thrombin, regardless of source, is FDA approved as an aid to hemostasis whenever oozing blood and minor bleeding from capillaries and small venules is accessible. In various types of surgery, solutions of thrombin may be used in conjunction with an absorbable gelatin sponge, USP for hemostasis.
Topical hemostatic agents in surgical practice - ScienceDirect
Control of liver hemorrhage: 14% of patients with hepatic injury undergo surgery in order to control bleeding. If there is major bleeding, techniques such as manual compression, topical hemostatic agents (physical agents that promote hemostasis or biologically active agents that enhance coagulation), or packing (applying physical pressure with several abdominal packs) are utilized.
[DOC File]VALVULAR CARDIAC SURGERY
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Topical hemostatic agents: gelfoam, avitene, surgicel, bone wax. Antibiotic irrigants. Topical papaverine for prevention of spasm during intracranial artery surgery. Methyl methacrylate with cranioplasty. Heparin saline irrigation again with intracranial artery surgery. Contrast solutions with cerebral arteriography. Gliadel wafers (tumor bed of glioblastoma)
[DOC File]National PBM Drug Monograph
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Topical hemostatic may be used (gelfoam pad strips with NS or thrombin) Patient may need to be defibrillated (have ready when closing aorta or atrium) CPB will be discontinued when patient is re-warmed (metz, tube clamps, metz) Pacing wires will be placed (atrial and ventricular) Chest tubes will be placed (1 mediastinal and 1 substernal)
[DOC File]NEUROSURGERY
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Grisson T, Fang R: Topical hemostatic agents and dressings in the prehospital setting. Curr Opin Anaesthesiol:2015;28:210-216. Grottke O, Fries D, Nascimento B: Perioperatively acquired disorders of coagulation. Curr Opin Anaesthesiol 2015;28:113-122
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