Acetyl coa carboxylase
[DOC File]Theranostics
https://info.5y1.org/acetyl-coa-carboxylase_1_784e3f.html
LONG CHAIN ACYL-COA INHIBITS FATTY ACID SYNTHESIS. Free fatty acid will be converted to the acyl-CoA by the reaction of Acyl-CoA synthetase. The long chain acyl-CoA produces metabolic feedback inhibition of the acetyl-CoA carboxylase which is the key enzyme for the fatty acids synthesis. 13.
[DOC File]Chapter 25
https://info.5y1.org/acetyl-coa-carboxylase_1_23280f.html
Answer: Acetyl-CoA carboxylase catalyzes the production of malonyl-CoA and inhibition of this enzyme will immediately inhibit fatty acid biosynthesis because malonyl-CoA is a substrate for fatty acid synthase. Malonyl has another regulatory role in fatty acid metabolism: it inhibits carnitine acyltransferase the enzyme responsible for fatty ...
[DOC File]Chapter 25
https://info.5y1.org/acetyl-coa-carboxylase_1_5f490d.html
Acetyl-CoA carboxylase (ACC) ACC, which carboxylates acetyl-CoA into malonyl-CoA, exhibits up-regulation in the breast, gastric, and lung cancers [68-70]. Furthermore, the distinctive elevation of ACC and FASN in iPSC emphasizes the importance of lipogenesis in stemness and beacons potential therapeutic utilization in CSCs.
Salih Wakil Lab
Acetyl-CoA carboxylase is active in a polymeric state. The equilibrium between active polymer and inactive protomers is affected by citrate and palmitoyl-CoA. Citrate is an allosteric activator of the enzyme and shifts the equilibrium to the polymer. Palmitoyl-CoA shifts the …
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