Dopamine levels and schizophrenia
[DOCX File]van Kammen DP, Kelley M. Dopamine and norepinephrine ...
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the side effects of reducing dopamine levels are unpleasant, (e.g. extrapyramidal dysfunction, dysphoria and anhedonia) especially in the periods in between acute episodes, where people with schizophrenia may revert to more ‘normal’ levels of dopamine; arguably typical anti-psychotics (i.e. dopamine antagonists) bring the person down to ...
[DOC File]The ‘Dopamine Hypothesis’ suggests that schizophrenia ...
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The evidence on the relationship between schizophrenia and dopamine levels is mostly correlation in nature. As a result, we do not know whether the changed dopamine activity in schizophrenics occurs before or after onset of the disorder. If it occurs after, then clearly dopamine plays a part in causing schizophrenic symptoms.
[DOC File]Treatment of Schizophrenia
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CSF dopamine ß-hydroxylase in schizophrenia: Associations with premorbid functioning and brain computerized tomography scan measures. Am J Psychiatry, …
[DOC File]Schizophrenia
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At the same time dopamine levels were elevated suggesting that a dysfunction of the prefrontal cortex is linked to dopamine abnormalities. Sigmundssen (2001) found that patients with type 2 schizophrenia have smaller amounts of grey matter and smaller temporal and frontal lobes.
[DOC File]Schizophrenic Disorders
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Furthermore, PET scans show that people with schizophrenia given amphetamines show higher levels of dopamine release in the basal ganglia than age-matched controls and are more likely to exhibit schizophrenic symptoms.
[DOCX File]Paper 2 Clinical: Studies – Carlsson et al (2000)
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Mar 30, 2016 · Drugs used to treat reduce dopamine (pleasure principle) and block receptors. Too much amphetamine (which raises dopamine levels) results in schizophrenic-like behavior called amphetamine psychosis Might be from brain structure – Schizophrenic patients tend to have enlarged ventricles (chambers in the brain filled with cerebral fluid).
What is the role of dopamine in schizophrenia?
The ‘Dopamine Hypothesis’ suggests that schizophrenia results from over-activity in the brain dopamine systems. Owen et al. (1978) found increased levels of dopamine and a relative excess of dopamine receptors in the brain tissue of schizophrenic patients.
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