Fatty acyl coa synthase
[DOC File]Chapter 22: Biosynthetic Pathways
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22.3 Biosynthesis of Fatty Acids. Acetyl CoA is the 2C starting material. This is used to add two carbons to growing Fatty Acid Stepwise. This explains why Fatty Acids always have an even number of carbons. This process occurs in the cytosol. Acyl Carrier Protein, ACP. Synthase is an enzyme that “holds” the growing Fatty Acid. CH3-C(O)-S ...
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A protein that carries the acyl groups during synthesis of fatty acids (coenzyme in fatty acid synthase complex) Give the names and formulas of the ketone bodies. Give the differences in the activities of phospholipase A 1 , A 2 , C and D.
[DOC File]Lipid Metabolism
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LONG CHAIN ACYL-COA INHIBITS FATTY ACID SYNTHESIS. Free fatty acid will be converted to the acyl-CoA by the reaction of Acyl-CoA synthetase. The long chain acyl-CoA produces metabolic feedback inhibition of the acetyl-CoA carboxylase which is the key enzyme for the fatty acids synthesis. 13.
[DOC File]University of Michigan
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Once in cell, acyl CoA synthase converts fatty acids to acyl CoA in the outer membrane of mitochondria or in ER. Any fatty acids C-12 or longer will use carnitine as a carrier to get into the mitochondrial matrix: carnitine palmitoyltransferase will transfer the acyl CoA (previously the fatty acid) onto carnitine, which will move through a ...
[DOC File]Exam #1
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A) malonyl-CoA synthase. B) acetyl CoA kinase. C) fatty acyl CoA synthetase. D) acetyl CoA carboxylase. E) acetyl CoA synthetase The following two questions refer to the pathway drawn above. 25) Which of the following statements describing the above pathway is correct? A) Acetyl CoA carboxylase attaches CoA to the free fatty acid to make ...
[DOC File]DESIGN OF ENERGY METABOLISM - USD Biology
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Acyl-CoA Synthetase in OMM and ER catalyzes: To get across mitochondrial membranes, carnitine serves as a carrier (reaction catalyzed by fatty acyl-CoA carnitine transferase) Once in mitochondrial matrix, reconverted to fatty acyl-CoA by acyl-CoA synthetase. (See Fig 6.11) Rate limiting step in (-oxidation is apparently (-hydroxyacyl CoA ...
[DOC File]E
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Understand importance of "priming" fatty acid with CoA to make fatty acyl-CoA. Transport fatty acid into mitochondria using carnitine acyltransferase (regulated step) -oxidation of fatty acids (breakdown) even # carbons - get acetyl CoA and FADH2 and NADH. odd # carbons - get acetyl CoA and FADH2 and NADH + succinyl CoA
[DOC File]Summary of key points:
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Fatty Acid Synthase . progressively adds 2 carbon units from malonyl CoA to a growing acyl chain to form the 16-carbon palmitic acid in process that requires 2NADPH for each addition. 4. Discuss the general mechanism of the fatty acid synthase reaction. Fatty Acid synthase. 2 components of the fatty acid complex are the . condensing enzyme (CE) and
[DOC File]Word count: 5713
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Fatty acids taken up by muscle from plasma and those derived from intracellular TG are "activated" by an enzyme called fatty acyl coenzyme A (CoA) synthase in the sarcoplasm of muscle. Activation involves reacting the fatty acid with CoA to produce fatty acyl CoA (activated fatty acid).
[DOC File]Hormones-Glycogen and Lipid Metabolism
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Fatty acids are degraded in mitochondria by the oxidation of the Acyl CoA (a thioester of the fatty acid) at the -carbon yielding Acetyl CoA which can be oxidized by the citric acid cycle. Before the can be -oxidized, the medium chain length FFA are converted into the fattyacyl CoA by acyl CoA synthase in the mitochondrial outer membrane (606).
[DOC File]Chapter 25
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Production of fatty acyl-CoA by acyl-CoA synthetase, which is used to activate fatty acids for beta oxidation, uses in effect two phosphoanhydride bonds to create the thioester bond. (As an interesting aside, synthase and synthetase both run reactions that join two substrates to form a product.
[DOC File]Chapter 20
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Fatty acyl-CoA dehydrogenase: Reduces coenzyme Q: No protons pumped. Complex III: Coenzyme Q-cytochrome c reductase. Components. Cytochromes bL and bH. Rieske protein: Fe-S protein. Q-cycle. Protons pumped. Complex IV: Cytochrome c oxidase. Components. Cytochrome a and CuA. Cytochrome a3 and CuB. Binuclear center: O2 consumption and H2O ...
[DOCX File]Clinical biochemistry / second stage Dr.Khawla A. Shemran
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The synthesis of fatty acids from acetyl-CoA and malonyl-CoA is carried out by fatty acid synthase (FAS). Note that this reaction is an energy requiring process (1 ATP per Malonyl-CoA formed). This multifunctional enzyme catalyzes the seven different reactions
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